2,617 results match your criteria ablation modalities

Retrograde intrarenal surgery versus percutaneous nephrolithotomy in larger kidney stones. Could SuperPulsed Thulium-fiber laser change the game?

Cent European J Urol 2021 16;74(2):229-234. Epub 2021 May 16.

Institute for Urology and Reproductive Health, Sechenov University, Moscow, Russian Federation.

Introduction: The aim of this article was to compare retrograde intrarenal surgery (RIRS) and percutaneous nephrolithotomy (PCNL) efficacy and safety with SuperPulsed Thulium-fiber laser (SP TFL) for stones 20 mm and larger.

Material And Methods: Patients with large kidney stones (20 mm and larger) were recruited to undergo PCNL or RIRS with SP TFL lithotripsy. Both groups were comparable in terms of stone size and density, operation time, laser-on time (LOT), stone-free rate, residual fragments and complication rate. Read More

View Article and Full-Text PDF

Updates on the Diagnosis and Management of Hepatocellular Carcinoma.

Euroasian J Hepatogastroenterol 2021 Jan-Jun;11(1):32-40

The Aga Khan University Hospital, Karachi, Pakistan.

Introduction: Globally, the incidence, as well as mortality, related to hepatocellular carcinoma (HCC) is on the rise, owing to relatively few curative options. Underlying cirrhosis is the most common etiology leading to HCC, but risk factors of cirrhosis show great regional variability. Over the years, there has been a steady development in the diagnostic and therapeutic modalities of HCC, including the availability of a wide range of systemic chemotherapeutic agents. Read More

View Article and Full-Text PDF

Radiofrequency ablation may improve the beneficial results of vertebroplasty for vertebral hemangiomas: analysis of 46 patients.

Neurol Res 2021 Jul 27:1-6. Epub 2021 Jul 27.

Department of Neurosurgery, Faculty of Medicine, Suleyman Demirel Univercity, Isparta, Turkey.

Objectives: To evaluate the effect of vertebroplasty (VP) alone or combined therapy of radiofrequency ablation (RFA) with vertebroplasty on pain relief with visual analog scale (VAS) and Oswestry Disability Index (ODI) scores in vertebral hemangiomas.

Methods: Forty-six patients with hemangiomas were evaluated retrospectively: 20 males and 26 females were included. In group 1 ( = 25) only VP was performed, while RFA+VP were performed in the same treatment session in group 2 ( = 21). Read More

View Article and Full-Text PDF

Atrio-oesophageal fistula following atrial fibrillation ablation: how to manage this dreaded complication?

Interact Cardiovasc Thorac Surg 2021 Jul 27. Epub 2021 Jul 27.

Sorbonne Université, Assistance Publique-Hôpitaux de Paris, Pitié-Salpêtrière Hospital,Department of Cardiac Surgery, Paris, France.

Objectives: Atrio-oesophageal fistula is a rare but serious complication of radiofrequency catheter ablation of atrial fibrillation. Therapeutic options are surgery, oesophageal stenting and conservative treatment (antibiotics and anticoagulation). However, there are no guidelines available. Read More

View Article and Full-Text PDF

Combined utility of one lung ventilation and artificial pneumothorax in thermal ablation of hepatic dome tumor: a technical note.

Diagn Interv Radiol 2021 Jul;27(4):564-566

Department of Anesthesiology, Singapore General Hospital, Singapore.

Radiofrequency ablation and microwave ablation are established treatment modalities for smaller (<3 cm) or isolated hepatic tumors. Transthoracic ablation of hepatic dome lesions is a well described technique. We report the use of one lung ventilation to facilitate the successful percutaneous transthoracic microwave ablation of a segment 8 hepatic dome lesion after induction of artificial pneumothorax. Read More

View Article and Full-Text PDF

Methimazole Desensitization in a 4-Year-Old With Refractory Graves Disease.

AACE Clin Case Rep 2021 Jul-Aug;7(4):273-276. Epub 2021 Feb 20.

Department of Pediatrics, Division of Diabetes and Endocrinology.

Objective: To describe a 4-year-old girl with Graves disease and methimazole allergy who underwent desensitization, allowing continued methimazole use when other treatments were contraindicated.

Methods: We formulated a desensitization plan utilizing cetirizine and prednisone for a patient with previously diagnosed Graves disease who developed urticaria and arthralgias from methimazole. She was admitted for monitoring of rash, urticaria, angioedema, and anaphylaxis. Read More

View Article and Full-Text PDF
February 2021

Thermal ablation in non-small cell lung cancer: a review of treatment modalities and the evidence for combination with immune checkpoint inhibitors.

Transl Lung Cancer Res 2021 Jun;10(6):2842-2857

Department of Respiratory Medicine, Royal Melbourne Hospital, Melbourne, Australia.

Lung cancer is the leading cause of cancer death worldwide, with approximately 1.6 million cancer related deaths each year. Prognosis is best in patients with early stage disease, though even then five-year survival is only 55% in some groups. Read More

View Article and Full-Text PDF

Multimodal therapy for hepatocellular carcinoma: the role of surgery.

L Mocan

Eur Rev Med Pharmacol Sci 2021 Jul;25(13):4470-4477

"Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania,

Objective: Liver cancer is one of the widest spread malignancies in the world and its incidence is still on the rise. The surgical resection of liver cancer has become a widely performed procedure with considerably improved outcomes, low mortality rate, transfusions, and post-op bed stay.

Materials And Methods: Our goal with this paper was to conduct a narrative review of the literature in regard to the surgical treatment of hepatocellular carcinoma (HCC). Read More

View Article and Full-Text PDF

Treatment Options and Post-Treatment Malignant Transformation Rate of Actinic Cheilitis: A Systematic Review.

Cancers (Basel) 2021 Jul 4;13(13). Epub 2021 Jul 4.

First Department of Dermatology and Venereology, School of Medicine, Aristotle University of Thessaloniki, P.O. Box 54643 Thessaloniki, Greece.

Actinic cheilitis is a premalignant condition that may evolve to squamous cell carcinoma. A consensus on its management has not been established, and large clinical trials are lacking. We aimed to review the existing data regarding the treatment of actinic cheilitis with various modalities regarding safety, efficacy, recursions, and post-treatment malignant transformation. Read More

View Article and Full-Text PDF

An Unusual Finding in a Patient Presenting for Pulmonary Thromboendarterectomy: Pulmonary Venous Thrombosis.

J Cardiothorac Vasc Anesth 2021 Jun 22. Epub 2021 Jun 22.

Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN.

Pulmonary venous thrombosis (PVT) is a rare but potentially devastating disease state with a largely unknown incidence. The most common etiologies of PVT are secondary to complications of lung surgery, malignancy, catheter ablation for atrial fibrillation, and idiopathic causes. Diagnosis can be challenging because presenting symptoms often are vague and nonspecific, or even asymptomatic, and traditional diagnostic modalities, such as chest radiography and arterial phase computed tomography scans, are poor techniques for diagnosis. Read More

View Article and Full-Text PDF

The Role of Interventional Endoscopic Ultrasound in Liver Diseases: What Have We Learnt?

Can J Gastroenterol Hepatol 2021 28;2021:9948979. Epub 2021 Jun 28.

Department of Internal Medicine, Hepatobiliary Division, Dr. Cipto Mangunkusumo National General Hospital, Universitas Indonesia, Jakarta, Indonesia.

Chronic liver disease (CLD) is still a major problem, where the disease progression will lead to liver cirrhosis (LC) or hepatocellular carcinoma (HCC). Portal hypertension (PH) management and loco-regional therapy for HCC have become the cornerstones in advanced liver disease management. Recently, there are studies looking at the potential role of interventional endoscopic ultrasound (EUS) in liver diseases. Read More

View Article and Full-Text PDF

A clinical deep learning framework for continually learning from cardiac signals across diseases, time, modalities, and institutions.

Nat Commun 2021 07 9;12(1):4221. Epub 2021 Jul 9.

Department of Engineering Science, University of Oxford, Oxford, UK.

Deep learning algorithms trained on instances that violate the assumption of being independent and identically distributed (i.i.d. Read More

View Article and Full-Text PDF

Linac-based STereotactic Arrhythmia Radioablation (STAR) for ventricular tachycardia: a treatment planning study.

Jpn J Radiol 2021 Jul 9. Epub 2021 Jul 9.

Radiation Oncology Department, General Regional Hospital "F. Miulli", Acquaviva delle Fonti, Bari, Italy.

Object: To analyze geometrical approaches, prescription modalities, and delivery efficiency for linear accelerator (Linac)-based STereotactic Arrhythmia Radioablation (STAR) for ventricular tachycardia.

Methods: The anatomy and planning target volume (PTV) of the first Italian STAR patient were used. To assess geometrical approaches, 3 plans prescribed to 75% isodose-line, differing for number, length of arcs, and couch rotations, were generated and compared (Plans#1-3). Read More

View Article and Full-Text PDF

[Comparison of Quality of Life of Patients with Papillary Thyroid Microcarcinoma Treated by Different Modalities].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2021 Jun;43(3):328-337

Department of Ultrasound,the First Medical Center of Chinese PLA General Hospital,Beijing 100853,China.

Objective To compare the health-related quality of life(HRQoL)of patients with papillary thyroid microcarcinoma(PTMC)treated by different modalities. Methods The PTMC patients after treatment who came to our department for follow-up from October to December in 2019 were enrolled and assigned into three groups according to treatment modalities:radiofrequency ablation(RFA)group(=80), hemithyroidectomy(HT)group(=34), and total thyroidectomy(TT)group(=35).All patients completed three scales:short form 36-item health survey(SF-36), thyroid cancer-specific health-related quality of life questionnaire(THYCA-QoL), and fear of progression questionnaire-short form(FoP-Q-SF). Read More

View Article and Full-Text PDF

Outcomes From Pediatric Ablation: A Review of 20 Years of National Data.

JACC Clin Electrophysiol 2021 Jun 22. Epub 2021 Jun 22.

Department of Paediatric Cardiology, Bristol Royal Hospital for Children, Bristol Heart Institute, University Hospital Bristol, Bristol, United Kingdom.

Objectives: This study set out to examine outcomes from pediatric supraventricular tachycardia ablations over a 20-year period. This study sought to examine success rates and repeat ablations over time and to evaluate whether modalities such as 3-dimensional (3D) mapping, contact force, and cryotherapy have improved outcomes.

Background: Ablation of supraventricular tachycardia in pediatric patients is commonly performed in most congenital heart centers with excellent long-term results. Read More

View Article and Full-Text PDF

Fractional versus full ablative CO laser in recipient site of non-cultured melanocytes and keratinocyte transplantation in treatment of vitiligo.

J Cosmet Dermatol 2021 Jul 2. Epub 2021 Jul 2.

Dermatology and Venereology Department, Faculty of Medicine for girls, Alazhar University, Cairo, Egypt.

Background: Melanocyte-keratinocyte transplant procedure (MKTP) or non-cultured epidermal cell suspension transplantation is a very popular surgical modality for treating stable vitiligo. The recipient-site preparation is one potential determinant in the repigmentation outcomes.

Aim: To assess the efficacy of fractional CO (FCO ) laser in recipient-site preparation before MKTP and comparing it to the frequently used full surface laser ablation. Read More

View Article and Full-Text PDF

Annular Fiber Probe for Interstitial Illumination in Photoacoustic Guidance of Radiofrequency Ablation.

Sensors (Basel) 2021 Jun 29;21(13). Epub 2021 Jun 29.

Multi-Modality Medical Imaging, Technical Medical Center, Faculty of Science and Technology, University of Twente, 7522 NB Enschede, The Netherlands.

Unresectable liver tumors are commonly treated with percutaneous radiofrequency ablation (RFA). However, this technique is associated with high recurrence rates due to incomplete tumor ablation. Accurate image guidance of the RFA procedure contributes to successful ablation, but currently used imaging modalities have shortcomings in device guidance and treatment monitoring. Read More

View Article and Full-Text PDF

Ablation Modalities for Therapeutic Intervention in Arrhythmia-Related Cardiovascular Disease: Focus on Electroporation.

J Clin Med 2021 Jun 16;10(12). Epub 2021 Jun 16.

Physiology and Cellular Physiology Laboratory, CÚRAM SFI Centre for Research in Medical Devices, School of Medicine, Human Biology Building, National University of Ireland (NUI) Galway, H91 W5P7 Galway, Ireland.

Targeted cellular ablation is being increasingly used in the treatment of arrhythmias and structural heart disease. Catheter-based ablation for atrial fibrillation (AF) is considered a safe and effective approach for patients who are medication refractory. Electroporation (EPo) employs electrical energy to disrupt cell membranes which has a minimally thermal effect. Read More

View Article and Full-Text PDF

Arrhythmogenic Cardiomyopathy-Current Treatment and Future Options.

J Clin Med 2021 Jun 22;10(13). Epub 2021 Jun 22.

Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padova, Via Giustiniani 2, 35128 Padova, Italy.

Arrhythmogenic cardiomyopathy (ACM) is an inheritable heart muscle disease characterised pathologically by fibrofatty myocardial replacement and clinically by ventricular arrhythmias (VAs) and sudden cardiac death (SCD). Although, in its original description, the disease was believed to predominantly involve the right ventricle, biventricular and left-dominant variants, in which the myocardial lesions affect in parallel or even mostly the left ventricle, are nowadays commonly observed. The clinical management of these patients has two main purposes: the prevention of SCD and the control of arrhythmic and heart failure (HF) events. Read More

View Article and Full-Text PDF

Diagnostic and Interventional Role of Endoscopic Ultrasonography for the Management of Pancreatic Neuroendocrine Neoplasms.

J Clin Med 2021 Jun 15;10(12). Epub 2021 Jun 15.

Department of Human Pathology of Adult and Pediatric Age, University of Messina, 98100 Messina, Italy.

Pancreatic neuroendocrine neoplasms (PanNENs) are relatively rare, but their incidence has increased significantly in the last decades. Precise diagnosis and prognostic stratification are crucial for proper patient management. Endoscopic ultrasound (EUS) is the modality of choice for diagnosis of solid pancreatic tumors, showing a higher tumor detection rate than other imaging modalities, especially for small size lesions. Read More

View Article and Full-Text PDF

Magnetic Nanoparticles in Biology and Medicine: Past, Present, and Future Trends.

Pharmaceutics 2021 Jun 24;13(7). Epub 2021 Jun 24.

Center for Biomedical Engineering, School of Engineering, Brown University, 171 Meeting Street, Providence, RI 02912, USA.

The use of magnetism in medicine has changed dramatically since its first application by the ancient Greeks in 624 BC. Now, by leveraging magnetic nanoparticles, investigators have developed a range of modern applications that use external magnetic fields to manipulate biological systems. Drug delivery systems that incorporate these particles can target therapeutics to specific tissues without the need for biological or chemical cues. Read More

View Article and Full-Text PDF

Challenges Facing Percutaneous Ablation in the Treatment of Hepatocellular Carcinoma: Extension of Ablation Criteria.

J Hepatocell Carcinoma 2021 21;8:625-644. Epub 2021 Jun 21.

Department of Hepatobiliary and Pancreatic Surgery, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, Henan Province, 450008, People's Republic of China.

As an emerging minimally invasive treatment method, percutaneous ablation is more and more widely used in the treatment of liver tumors. It has been recommended by guidelines for diagnosis and treatment of hepatocellular carcinoma (HCC) as a curative treatment alongside surgical resection and liver transplantation. In recent years, with the continuous advancement and innovation of percutaneous ablation technologies, their clinical efficacy and safety have been significantly improved, which has led to the expanded application of percutaneous ablation in the treatment of HCC-more and more patients who were previously considered unsuitable for ablation therapies are now being treated with percutaneous ablation. Read More

View Article and Full-Text PDF

Image-Guided Surgical Simulation in Minimally Invasive Liver Procedures: Development of a Liver Tumor Porcine Model Using a Multimodality Imaging Assessment.

J Laparoendosc Adv Surg Tech A 2021 Jun 25. Epub 2021 Jun 25.

IHU-Strasbourg, Institute of Image-Guided Surgery, Strasbourg, France.

Image-guided liver surgery and interventions are growing as part of the current trend to translate liver procedures into minimally invasive approaches. Hands-on surgical training in such techniques is required. Consequently, a meaningful and realistic liver tumor model using multi-imaging modalities, such as ultrasound (US), computed tomography (CT), magnetic resonance (MR), cone beam-CT (CBCT), is mandatory. Read More

View Article and Full-Text PDF

Current Understanding of Ablative Radiation Therapy in Hepatocellular Carcinoma.

J Hepatocell Carcinoma 2021 14;8:575-586. Epub 2021 Jun 14.

Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, Ontario, Canada.

The role of ablative stereotactic body radiotherapy (SBRT) in hepatocellular carcinoma (HCC) has been evolving over the last few decades. SBRT has mostly been used in early stages of HCC, including few (≤ 3 in number) tumors, small tumours (< 3 cm in size), as well as larger tumours which are ineligible for other ablative modalities, mostly without vascular invasion. In early stage HCC, SBRT is used as a definitive treatment with curative intent or with intent to bridge to liver transplant. Read More

View Article and Full-Text PDF

Application of the woodchuck animal model for the treatment of hepatitis B virus-induced liver cancer.

World J Gastrointest Oncol 2021 Jun;13(6):509-535

Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC 20057, United States.

This review describes woodchucks chronically infected with the woodchuck hepatitis virus (WHV) as an animal model for hepatocarcinogenesis and treatment of primary liver cancer or hepatocellular carcinoma (HCC) induced by the hepatitis B virus (HBV). Since laboratory animal models susceptible to HBV infection are limited, woodchucks experimentally infected with WHV, a hepatitis virus closely related to HBV, are increasingly used to enhance our understanding of virus-host interactions, immune response, and liver disease progression. A correlation of severe liver pathogenesis with high-level viral replication and deficient antiviral immunity has been established, which are present during chronic infection after WHV inoculation of neonatal woodchucks for modeling vertical HBV transmission in humans. Read More

View Article and Full-Text PDF

Structure-Driven Unsupervised Domain Adaptation for Cross-Modality Cardiac Segmentation.

IEEE Trans Med Imaging 2021 Jun 23;PP. Epub 2021 Jun 23.

Performance degradation due to domain shift remains a major challenge in medical image analysis. Unsupervised domain adaptation that transfers knowledge learned from the source domain with ground truth labels to the target domain without any annotation is the mainstream solution to resolve this issue. In this paper, we present a novel unsupervised domain adaptation framework for cross-modality cardiac segmentation, by explicitly capturing a common cardiac structure embedded across different modalities to guide cardiac segmentation. Read More

View Article and Full-Text PDF

Functional roles of female sex hormones and their nuclear receptors in cervical cancer.

Essays Biochem 2021 Jun 22. Epub 2021 Jun 22.

Center for Nuclear Receptors and Cell Signaling, Department of Biology and Biochemistry, University of Houston, Houston, TX 77204, U.S.A.

There has been little progress for several decades in modalities to treat cervical cancer. While the cervix is a hormone-sensitive tissue, physiologic roles of estrogen receptor α (ERα), progesterone receptor (PR), and their ligands in this tissue are poorly understood. It has hampered critical assessments of data in early epidemiologic and clinical studies for cervical cancer. Read More

View Article and Full-Text PDF

The Efficacy of Sphenopalatine Ganglion Block and Radiofrequency Denervation in the Treatment of Cluster Headache: A Case Series.

Anesth Pain Med 2020 Dec 22;10(6):e104466. Epub 2020 Nov 22.

Department of Anesthesiology, Critical Care and Pain Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Background: Cluster headache is a variant of primary neurovascular headaches. some patients with cluster headache are not responsive to medical treatment and may benefit from interventional modalities, including sphenopalatine ganglion block and denervation.

Objectives: Our purpose was to evaluate the efficacy of sphenopalatine ganglion block/denervation in the treatment of cluster headache. Read More

View Article and Full-Text PDF
December 2020

Focused Ultrasound Ablation of an Arteriovenous Malformation Model.

Front Neurol 2021 3;12:671380. Epub 2021 Jun 3.

Department of Radiology, School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.

Brain AVMs are rare but serious vascular lesions that often pose a management dilemma between the risk of various treatment modalities and uncertain natural history during observation. We describe preliminary data on the use of focused ultrasound as a novel therapeutic strategy. In an AVM model, one session of ultrasound gradually reduced flow through the lesion without inducing rupture. Read More

View Article and Full-Text PDF

Contemporary practice patterns of transurethral therapies for benign prostate hypertrophy: results of a worldwide survey.

World J Urol 2021 Jun 18. Epub 2021 Jun 18.

Feinberg School of Medicine, Department of Urology, Northwestern University, 676 N. St. Clair, Suite 2300, Chicago, IL, 60611, USA.

Purpose: To perform a global survey to identify contemporary practice patterns of transurethral therapies for benign prostatic hypertrophy.

Methods: A REDCap survey was distributed to the ~ 3500 members of the Endourological Society. Surgeons completed demographic information and then selected the BPH therapies they perform 10 cases/year. Read More

View Article and Full-Text PDF