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Explaining cross-cultural variation in mirror self-recognition: New insights into the ontogeny of objective self-awareness.

Dev Psychol 2021 May;57(5):625-638

Department of Human Behavior, Ecology and Culture, Max Planck Institute for Evolutionary Anthropology.

Mirror self-recognition (MSR) is considered to be the benchmark of objective self-awareness-the ability to think about oneself. Cross-cultural research showed that there are systematic differences in toddlers' MSR abilities between 18 and 24 months. Understanding whether these differences result from systematic variation in early social experiences will help us understand the processes through which objective self-awareness develops. Read More

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Numerical activities of daily living: a short version.

Neurol Sci 2021 Jun 23. Epub 2021 Jun 23.

Department of Neuroscience (Padova Neuroscience Center), University of Padova, Padua, Italy.

Specific impairments in numerical functions may cause severe problems in everyday life that cannot be inferred from the available scales evaluating instrumental activities of daily living. The Numerical Activities of Daily living (NADL) is a battery designed to assess the patient's performance in everyday activities involving numbers (Informal Test) and in more scholastic capacities (Formal Test). A downside of this battery is its duration (45 min). Read More

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MiR-137 inhibits the proliferation, invasion and migration of glioma via targeting to regulate EZH2.

Genes Genomics 2021 Jun 23. Epub 2021 Jun 23.

The Fourth Department of Neurosurgery, Tangshan Gongren Hospital, No. 27, Wenhua Road, North District, Tangshan, 063000, Hebei, People's Republic of China.

Background: Gliomas are common malignant tumors in the nervous system, known for poor prognosis and low survival rate.

Objective: This study aims to explore functions of miR-137 in glioma progression and identify messenger RNAs (mRNA) regulated by miR-137, which provides new ideas for further exploration of glioma therapeutic targets.

Methods: Gene expression data were downloaded from the Cancer Genome Atlas database, and abnormally expressed miRNAs and mRNAs in glioma were analyzed. Read More

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Limitation of microbial processes at saturation-level salinities in a microbial mat covering a coastal saltflat.

Appl Environ Microbiol 2021 Jun 23:AEM0069821. Epub 2021 Jun 23.

Max-Planck-Institute for Marine Microbiology, Celsiusstrasse 1, 28359 Bremen, Germany.

Hypersaline microbial mats are dense microbial ecosystems capable of performing complete element cycling and are considered analogs of Early Earth and hypothetical extraterrestrial ecosystems. We studied the functionality and limits of key biogeochemical processes, such as photosynthesis, aerobic respiration, and sulfur cycling in salt crust-covered microbial mats from a tidal flat at the coast of Oman. We measured light, oxygen, and sulfide microprofiles as well as sulfate-reduction rates at salt saturation and in flood conditions and determined fine-scale stratification of pigments, biomass, and microbial taxa in the resident microbial community. Read More

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Methanotrophic denitrification in wastewater treatment: microbial aspects and engineering strategies.

Crit Rev Biotechnol 2021 Jun 22:1-17. Epub 2021 Jun 22.

Department of Hydraulics and Sanitation, São Carlos School of Engineering (EESC), University of São Paulo (USP), São Carlos, Brazil.

Anaerobic technologies are consolidated for sewage treatment and are the core processes for mining marketable products from waste streams. However, anaerobic effluents are supersaturated with methane, which represents a liability regarding greenhouse gas emissions. Meanwhile, anaerobic technologies are not capable of nitrogen removal, which is required to ensure environmental protection. Read More

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Effects of bovine cancellous bone powder/ poly amino acid composites on cellular behaviours and osteogenic performances.

Biomed Mater 2021 Jun 22. Epub 2021 Jun 22.

School of Automation & Information Engineering, Sichuan University of Science and Engineering, No.519 Huixing Road, Zigong , China, 643000, Zigong, Sichuan, 643000, CHINA.

Xenogeneic bone has good biological activity, but eliminating immunogenicity, while retaining osteogenic abilities, is a challenge. By combining xenogeneic bone with poly amino acid (PAA) that has an amide bond structure, a new type of composite conforming to bionics and low immunogenicity may be obtained. In this study, according to the principles of component bionics, three composites of delipidized cancellous bone powder (DCBP) and PAA were designed and obtained by an in situ polycondensation method (IP), an extrusion moulding method (EM), and a solution-blend method (SB). Read More

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MiR-150 suppressed cell viability, invasion and EMT via HMGA2 in oral squamous cell carcinoma.

Eur Rev Med Pharmacol Sci 2021 Jun;25(11):3981-3989

Department of Stomatology, Yantaishan Hospital, Yantai, China.

Objective: Oral squamous cell carcinoma (OSCC) accounts for 90% of head and neck cancers, and its 5-year overall survival is very poor. MiR-150 is usually downregulated and acts as tumor suppressor in multiple cancers. The aim of our study is to explore the functions of miR-150 in OSCC. Read More

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Assessing the mechanism of barriers towards green finance and public spending in small and medium enterprises from developed countries.

Environ Sci Pollut Res Int 2021 Jun 22. Epub 2021 Jun 22.

Jiangsu University, Zhenjiang, China.

Due to their different abilities to improve financial growth and improve social development, small and medium enterprises (SMEs) have been referred to as the economy's backbone. Small- and medium-sized enterprises are crucial for both high- and low-income nations' financial development. Customers grow more conscious of their purchase choices, preferences, and environmental consequences. Read More

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Wiad Lek 2021 ;74(4):874-879


Objective: The aim: Is to study the level of knowledge, skills, abilities, and health indicators of students during the formation of their healthy lifestyle.

Patients And Methods: Materials and methods: The research was conducted at Zhytomyr Ivan Franko State University and Polissya National University in 2018-2020. Thus, 882 students (385 males and 497 females) of different specialties between the ages of 17 and 23 were examined. Read More

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The influential factors and intervention strategies that engage malignant cancer patients in health-promoting behaviors during PICC line maintenance.

Am J Transl Res 2021 15;13(5):5208-5215. Epub 2021 May 15.

Department of Breast and Thoracic Tumors Surgery, The First Affiliated Hospital of Hainan Medical University Haikou 570100, Hainan Province, China.

Objective: To analyze the influential factors and intervention strategies involved in engaging health-promoting behaviors (EHPD) during peripheral central venous catheter (PICC) line maintenance in malignant tumor patients.

Methods: 120 patients with malignant tumors who underwent PICC line maintenance in our hospital were prospectively analyzed. They were divided into a low and moderate level group (HPLP-II score ≤137) and a high level group (HPLP-II score >137) according to their Health Promoting Lifestyle Profile II (HPLP-II) questionnaire scores. Read More

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Word reading, vocabulary, and mental health problems in adolescent girls and boys with intellectual and developmental disabilities.

Int J Dev Disabil 2019 Jun 18;67(2):131-139. Epub 2019 Jun 18.

Speech and Language Pathology Unit & the Gillberg Neuropsychiatry Centre, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden.

Reading difficulties are linked to several disadvantages in the general population. Less is known about correlates of reading difficulties in individuals with intellectual and severe developmental disabilities (IDD). Vocabulary and word reading were assessed in 112 adolescents with IDD, recruited from Special needs comprehensive schools in Sweden ( in Swedish). Read More

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Predictive Value of Developmental Assessment in a Neonatal Intensive Care Unit (NICU) Follow-Up Clinic.

J Pediatr Psychol 2021 Jun 18. Epub 2021 Jun 18.

Department of Pediatrics, University of Minnesota Medical School.

Objective: Neonatal Intensive Care Unit (NICU) Follow-Up programs vary in the duration for which they monitor child development and neurocognitive outcomes. This study explores the early predictive value of a widely used developmental measure for intellectual functioning during early childhood to better inform whether there is value added in continued monitoring.

Methods: Participants were 209 children who had at least two assessments between the ages of 1 and 6 years old as part of NICU Follow-Up clinic. Read More

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The potential role of melatonin in retarding intervertebral disc ageing and degeneration: A systematic review.

Ageing Res Rev 2021 Jun 15;70:101394. Epub 2021 Jun 15.

Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Electronic address:

Intervertebral disc degeneration (IDD) is a common degenerative disease of the musculoskeletal system that develops with age. It is regarded as the main cause of chronic low back pain in the elderly. IDD has various causes, including ageing, mechanical overloading, and nutritional deficiency. Read More

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Proteomic responses of the coccolithophore Emiliania huxleyi to zinc limitation and trace metal substitution.

Environ Microbiol 2021 Jun 17. Epub 2021 Jun 17.

Dept. of Earth and Environmental Science, Rutgers University - Newark, Newark, NJ.

Zinc concentrations in pelagic surface waters are within the range that limits growth in marine phytoplankton cultures. However, the influence of zinc on marine primary production and phytoplankton communities is not straightforward due to largely uncharacterized abilities for some phytoplankton to access zinc species that may not be universally bioavailable and substitute zinc with cobalt or cadmium. We used a quantitative proteomic approach to investigate these strategies and other responses to zinc limitation in the coccolithophore Emiliania huxleyi, a dominant species in low zinc waters. Read More

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Effect of Working Memory Load and Typicality on Semantic Processing in Aphasia.

Am J Speech Lang Pathol 2021 Jun 17:1-18. Epub 2021 Jun 17.

Temple University, Philadelphia, PA.

Purpose This study evaluated the effects of a linguistic characteristic, typicality, and a processing variable, working memory on the abilities of people with aphasia (PWA) and neurologically intact adults to process semantic representations. This was accomplished using a newly developed assessment task, the Category Typicality Test, which was created for the Temple Assessment of Language and Short-Term Memory in Aphasia. Method A post hoc quasi-experimental design was used. Read More

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Literacy can enhance syntactic prediction in spoken language processing.

J Exp Psychol Gen 2021 Jun 17. Epub 2021 Jun 17.

Department of Psychology of Language.

Language comprehenders can use syntactic cues to generate predictions online about upcoming language. Previous research with reading-impaired adults and healthy, low-proficiency adult and child learners suggests that reading skills are related to prediction in spoken language comprehension. Here, we investigated whether differences in literacy are also related to predictive spoken language processing in non-reading-impaired proficient adult readers with varying levels of literacy experience. Read More

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Tuning Atomically Dispersed Fe Sites in Metal-Organic Frameworks Boosts Peroxidase-Like Activity for Sensitive Biosensing.

Nanomicro Lett 2020 Sep 23;12(1):184. Epub 2020 Sep 23.

Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan, 430079, People's Republic of China.

Although nanozymes have been widely developed, accurate design of highly active sites at the atomic level to mimic the electronic and geometrical structure of enzymes and the exploration of underlying mechanisms still face significant challenges. Herein, two functional groups with opposite electron modulation abilities (nitro and amino) were introduced into the metal-organic frameworks (MIL-101(Fe)) to tune the atomically dispersed metal sites and thus regulate the enzyme-like activity. Notably, the functionalization of nitro can enhance the peroxidase (POD)-like activity of MIL-101(Fe), while the amino is poles apart. Read More

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September 2020

miR-455 Inhibits the Viability and Invasion by Targeting RAB18 in Hepatocellular Carcinoma.

J Oncol 2021 27;2021:9923454. Epub 2021 May 27.

Department of Medical Insurance Office, Qilu Hospital of Shandong University, Jinan 250012, China.

Background: Hepatocellular carcinoma (HCC) has been regarded as the fifth most common cancer worldwide with a low prognosis. miR-455 usually played the role of a tumor suppressor in multiple cancers. The aim of this study was to investigate the roles of miR-455 in HCC. Read More

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Pannexin 1 mediates gastric cancer cell epithelial-mesenchymal transition via aquaporin 5.

Biol Pharm Bull 2021 Jun 16. Epub 2021 Jun 16.

Department of Thyroid and Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University.

Pannexin 1 (PANX1) has been implicated in cancer emergence and progression. However, its roles in gastric cancer remain unclear. In the present study, the function and molecular mechanisms of PANX1 in gastric cancer were investigated in vitro. Read More

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Development of a method for phycocyanin recovery from filamentous cyanobacteria and evaluation of its stability and antioxidant capacity.

BMC Biotechnol 2021 Jun 16;21(1):40. Epub 2021 Jun 16.

College of Agriculture, Ibaraki University, 3-21-1 Ami, Ibaraki 300-0393, Japan.

Background: Most commercial phycocyanins are extracted from a filamentous cyanobacterium, Arthrospira (Spirulina) platensis. Owing to the expenses of culture and complexities of the physical and chemical methods of phycocyanin purification, a more effective and simple method is required.

Results: We developed a new method for efficiently recovering the blue pigment protein, phycocyanin, from unique filamentous cyanobacteria, Pseudanabaena sp. Read More

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Cheese quality from cows given a tannin extract in 2 different grazing seasons.

J Dairy Sci 2021 Jun 11. Epub 2021 Jun 11.

Independent researcher at INRAE, Université Clermont Auvergne, Vetagro Sup, UMRH, 63122, Saint-Genès-Champanelle, France.

The aim of the present study was to compare the effect of dietary tannins on cow cheese quality in 2 different grazing seasons in the Mediterranean. Two experiments were performed on 14 dairy cows reared in an extensive system. The first experiment took place in the wet season (WS), and the second experiment took place in the dry season (DS). Read More

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Breastfeeding and employed mothers in Ethiopia: legal protection, arrangement, and support.

Int Breastfeed J 2021 Jun 14;16(1):45. Epub 2021 Jun 14.

College of Medicine and Health Science Ambo University, Ambo, Ethiopia.

Background: Breastfeeding is the single, most cost-effective intervention to reduce worldwide child mortality. Women empowerment interventions have positive impacts on child and maternal nutritional, and health status. Women's employment and economic participation in Ethiopia have shown progress over the past three decades. Read More

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Type 2 diabetes patients' views on prevention of hypoglycaemia - a mixed methods study investigating self-management issues and self-identified causes of hypoglycaemia.

BMC Fam Pract 2021 Jun 14;22(1):114. Epub 2021 Jun 14.

Unit of PharmacoTherapy, Epidemiology and Economics, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, The Netherlands.

Background: Hypoglycaemia is a common and potentially avoidable adverse event in people with type 2 diabetes (T2D). It can reduce quality of life, increase healthcare costs, and reduce treatment success. We investigated self-management issues associated with hypoglycaemia and self-identified causes of hypoglycaemia in these patients. Read More

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The effects of age and verbal ability on word predictability in reading.

Psychol Aging 2021 Jun 24;36(4):531-542. Epub 2021 May 24.

Department of Communication Sciences & Disorders, University of Iowa.

Increased predictability effects in older compared to younger adults have been mostly observed in late eye-movement measures during reading. However, it is unclear whether and how these effects may be related to verbal ability, which typically improves with age. Past studies have shown that verbal abilities modulate the predictability effect. Read More

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A Critical Review of Spatial Abilities in Down and Williams Syndromes: Not All Space Is Created Equal.

Front Psychiatry 2021 28;12:669320. Epub 2021 May 28.

Institute of Psychology, University of Lausanne, Lausanne, Switzerland.

Down syndrome (DS, Trisomy 21) and Williams syndrome (WS) are two neurodevelopmental disorders of genetic origin that are accompanied by mild to moderate intellectual disability but exhibit distinct cognitive profiles. In this review we discuss our recent work characterizing the real-world spatial learning and memory abilities of adult individuals with DS and WS. We used several different paradigms in which participants locomote freely and have access to coherent input from all sensory modalities to investigate their fundamental egocentric (body-centered or viewpoint-dependent) and allocentric (world-centered or viewpoint-independent) spatial abilities. Read More

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Therapeutic oxygen delivery by perfluorocarbon-based colloids.

Adv Colloid Interface Sci 2021 May 1;294:102407. Epub 2021 May 1.

Harangoutte Institute, 68160 Ste Croix-aux-Mines, France.

After the protocol-related indecisive clinical trial of Oxygent, a perfluorooctylbromide/phospholipid nanoemulsion, in cardiac surgery, that often unduly assigned the observed untoward effects to the product, the development of perfluorocarbon (PFC)-based O nanoemulsions ("blood substitutes") has come to a low. Yet, significant further demonstrations of PFC O-delivery efficacy have continuously been reported, such as relief of hypoxia after myocardial infarction or stroke; protection of vital organs during surgery; potentiation of O-dependent cancer therapies, including radio-, photodynamic-, chemo- and immunotherapies; regeneration of damaged nerve, bone or cartilage; preservation of organ grafts destined for transplantation; and control of gas supply in tissue engineering and biotechnological productions. PFC colloids capable of augmenting O delivery include primarily injectable PFC nanoemulsions, microbubbles and phase-shift nanoemulsions. Read More

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Core-Peripheral Temperature Gradient and Skin Temperature as Predictors of Major Adverse Events Among Postoperative Pediatric Cardiac Patients.

J Cardiothorac Vasc Anesth 2021 May 18. Epub 2021 May 18.

Department of Pediatric Intensive Care Unit, The Royal Children's Hospital, Melbourne, Victoria, Australia.; Department of Pediatrics, University of Melbourne, Melbourne, Victoria, Australia.; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.

Objective: During episodes of low cardiac output, sympathetic neurohumoral responses with peripheral vasoconstriction result in an increase in the core-peripheral temperature gradient (CPTG). However, assessment of CPTG as a surrogate of low cardiac output and a predictor of outcomes in pediatric cardiac patients rarely has been performed. In this retrospective study, the authors assessed the prognostic abilities of CPTG, skin temperature, and serum lactate level for predicting clinical outcomes. Read More

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High-efficiency removal of tetracycline by carbon-bridge-doped g-CN/FeO magnetic heterogeneous catalyst through photo-Fenton process.

J Hazard Mater 2021 Jun 7;418:126333. Epub 2021 Jun 7.

Jiangsu Baichuan High-Tech New Materials Co., Ltd, Nanjing, China.

Carbon-bridge-modified malonamide (MLD)/g-CN (CN) was prepared by copolymerization of MLD with urea and melamine and loaded with FeO for the high-efficiency removal of tetracycline (TC) in water under photo-Fenton. The prepared catalysts were characterized by SEM, TEM, N adsorption-desorption analysis, XPS, XRD, and FTIR, which proved that the modification method successfully introduced the C bridge into the carbon nitride molecular system and increased the structural defects of the catalyst. The Carbon-bridge-modified MLD/CN/FeO also had good visible-light response and charge-separation and transport abilities in the photoelectrochemical test. Read More

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Enhanced expression of miR-889 forecasts an unfavorable prognosis and facilitates cell progression in hepatocellular carcinoma.

Diagn Pathol 2021 Jun 11;16(1):51. Epub 2021 Jun 11.

School of Pharmacy, Harbin University of Commerce, 138 Tongda Street, Harbin, 150076, Heilongjiang, China.

Background: As a new type of molecular marker, microRNAs (miRNAs) can be used for early diagnosis and prognosis prediction of malignant tumors, and has broad clinical application prospects. This paper mainly studies the important role of miR-889 in the occurrence and development of hepatocellular carcinoma and the prognostic significance of miR-889 in hepatocellular carcinoma.

Methods: Quantitative real-time PCR analysis detected the expression levels of miR-889 in hepatocellular carcinoma tissues and cell lines. Read More

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