Anal Chim Acta 2021 May 26;1160:338450. Epub 2021 Mar 26.
Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety, Tianjin Institute of Environmental and Operational Medicine, Tianjin, 300050, PR China. Electronic address:
T-2 toxin is a class A trichothecene mycotoxin produced by Fusarium, which exhibits genotoxic, cytotoxic, and immunotoxic effects in animals and humans. In this study, we developed an aptasensor for the sensitive detection of T-2 toxin, which was based on fluorescence resonance energy transfer (FRET), and acted by adjusting the electric potential on the surface of upconversion nanoparticles (UCNPs) and MIL-101(Cr). In addition, it combined the excellent spectral properties of UCNPs with the good adsorption quenching abilities of metal organic frameworks (MOFs). Read More