37,749 results match your criteria abdominal muscle


Pathophysiological Aspects of the Development of Abdominal Aortic Aneurysm with a Special Focus on Mitochondrial Dysfunction and Genetic Associations.

Biomol Concepts 2021 Jun 11;12(1):55-67. Epub 2021 Jun 11.

Department of Basic Research, Institute for Atherosclerosis Research, Moscow121609, Russia.

Abdominal aortic aneurysm (AAA) is a complex degenerative vascular disease, with considerable morbidity and mortality rates among the elderly population. The mortality of AAA is related to aneurysm expansion (the enlargement of the aortic diameter up to 30 mm and above) and the subsequent rupture. The pathogenesis of AAA involves several biological processes, including aortic mural inflammation, oxidative stress, vascular smooth muscle cell apoptosis, elastin depletion, and degradation of the extracellular matrix. Read More

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Clinical utility of ultrasonography imaging in musculoskeletal conditions: A Systematic review and Meta-analysis.

J Med Ultrason (2001) 2021 Jun 11. Epub 2021 Jun 11.

School of Physiotherapy, D.Y. Patil University, Navi Mumbai, 400706, India.

Optimising ultrasonography imaging (UI) applications for clients is a highly specific and sensitive add-on method. The aim of this meta-analysis was to systematically evaluate the clinical utilisation of UI in musculoskeletal conditions by rehabilitation providers in the past decade. Two reviewers independently assessed relevant research articles from five databases electronically (Medline, Cochrane Library, EMBASE, ProQuest, EBSCO) and screened titles and abstracts based on predefined eligibility criteria (2010- 2020). Read More

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Caldesmon ablation in mice causes umbilical herniation and alters contractility of fetal urinary bladder smooth muscle.

J Gen Physiol 2021 Jul 11;153(7). Epub 2021 Jun 11.

Institute of Vegetative Physiology, Center of Physiology, Faculty of Medicine, University of Cologne, Cologne, Germany.

The actin-, myosin-, and calmodulin-binding protein caldesmon (CaD) is expressed in two splice isoforms: h-CaD, which is an integral part of the actomyosin domain of smooth muscle cells, and l-CaD, which is widely expressed and is involved in many cellular functions. Despite extensive research for many years, CaD's in vivo function has remained elusive. To explore the role of CaD in smooth muscle contraction in vivo, we generated a mutant allele that ablates both isoforms. Read More

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Effect of portable non-invasive ventilation on thoracoabdominal volumes in recovery from intermittent exercise in patients with COPD.

J Appl Physiol (1985) 2021 06 10. Epub 2021 Jun 10.

Department of Sport, Exercise and Rehabilitation, Northumbria University, Newcastle Upon-Tyne, United Kingdom.

Background: We previously showed that use of portable non-invasive ventilation (pNIV) during recovery periods within intermittent exercise improved breathlessness and exercise tolerance in COPD patients compared to pursed-lip breathing (PLB). However, in a minority of patients recovery from dynamic hyperinflation (DH) was better with PLB, based on inspiratory capacity. We further explored this using Optoelectronic Plethysmography to assess total and compartmental thoracoabdominal volumes. Read More

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Ovarian clear cell carcinoma with an immature teratoma component showing ARID1A deficiency and an identical PIK3CA mutation.

J Obstet Gynaecol Res 2021 Jun 9. Epub 2021 Jun 9.

Department of Pathology, Jichi Medical University, Tochigi, Japan.

We herein report a case of ovarian clear cell carcinoma with an immature teratoma component that exhibited aggressive behavior. A 47-year-old woman presented with abdominal distention, and computed tomography detected a cystic mass on the right ovary. The resected mass had mural nodules, most of which showed a pale-yellow appearance; some nodules had a heterogeneous cut surface with bright yellow and white areas. Read More

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Body Composition Parameters May Be Prognostic Factors in Upper Urinary Tract Urothelial Carcinoma Treated by Radical Nephroureterectomy.

Front Oncol 2021 24;11:679158. Epub 2021 May 24.

West China Hospital, Sichuan University, Chengdu, China.

Objective: This study assessed the association between body composition and prognosis of patients with upper urinary tract urothelial carcinoma (UTUC) patients treated by radical nephroureterectomy.

Methods: We retrospectively collected baseline data on age, sex, body mass index (BMI), hypertension, diabetes, and tumor-related factors. Computed tomography (CT) scans were performed to measure body composition parameters such as muscle attenuation (MA), total abdominal muscle area (TAMA), visceral fat area (VFA), intermuscular fat area (IMF), and lateral/posterior perirenal fat thickness (L/P PNF), visceral fat density (VD), and subcutaneous fat density (SD). Read More

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Intramuscular Expression of Plasmid-Encoded FVII-Fc Immunoconjugate for Tumor Immunotherapy by Targeting Tumoral Blood Vessels and Cells.

Front Oncol 2021 24;11:638591. Epub 2021 May 24.

National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, China.

Tissue factor (TF) has been confirmed to be specifically expressed by vascular endothelial cells (VECs) in solid tumors and certain types of malignant tumor cells. Coagulation factor VII (FVII) can specifically bind to TF with high affinity, so the FVII-TF interaction provides an ideal target for tumor therapy. Expression of proteins in skeletal muscles is a simple and economical avenue for continuous production of therapeutic molecules. Read More

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[A Case of Pelvic Unicentric Castleman Disease Treated by Preoperative Transcatheter Arterial Embolization and Tumor Complete Resection with Combined Lower Abdominal and Posterior Approach].

Hinyokika Kiyo 2021 Apr;67(4):157-162

The Department of Urology, Kyoto University Hospital.

A 22-year-old woman was referred to our hospital for further examination of an incidentally discovered hypervascular pelvic tumor with a maximum diameter of 10 cm. Although Castleman disease was suspected based on the imaging findings and pathologic findings of the needle biopsy, a definitive diagnosis was not made. Preoperative transcatheter arterial embolization was performed to decrease intraoperative bleeding, and tumor resection was performed on the following day. Read More

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Reference Values for Skeletal Muscle Mass at the Third Lumbar Vertebral Level Measured by Computed Tomography in a Healthy Korean Population.

Endocrinol Metab (Seoul) 2021 Jun 8. Epub 2021 Jun 8.

School of Computer Science and Engineering, Soongsil University, Seoul, Korea.

Background: Sarcopenia is defined as the loss of skeletal muscle mass and is associated with negative clinical outcomes. This study aimed to establish sex-specific cutoff values for the skeletal muscle area (SMA) and skeletal muscle index (SMI) at the third lumbar vertebral (L3) level using computed tomography (CT) imaging to identify sarcopenia in healthy Korean liver donors.

Methods: This retrospective study included 659 healthy liver donors (408 men and 251 women) aged 20 to 60 years who had undergone abdominal CT examinations between January 2017 and December 2018. Read More

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Impaired skeletal muscle fatigue resistance during cardiac hypertrophy is prevented by functional overload- or exercise-induced functional capillarity.

J Physiol 2021 Jun 9. Epub 2021 Jun 9.

School of Biomedical Sciences, University of Leeds, UK.

Key Points: Capillary rarefaction is hypothesised to contribute to impaired exercise tolerance in cardiovascular disease, but it remains a poorly exploited therapeutic target for improving skeletal muscle performance. Using an abdominal aortic coarctation rat model of compensatory cardiac hypertrophy, we determine the efficacy of aerobic exercise for the prevention of, and mechanical overload for restoration of hind limb muscle fatigue resistance and microvascular impairment in the early stages of heart disease. Impaired muscle fatigue resistance was found after development of cardiac hypertrophy, but this impairment was prevented by low intensity aerobic exercise and recovered after mechanical stretch due to muscle overload. Read More

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Comparison between skeletal muscle and adipose tissue measurements with high-dose CT and low-dose attenuation correction CT of F-FDG PET/CT in elderly Hodgkin lymphoma patients: a two-centre validation.

Br J Radiol 2021 Jun 9:20200672. Epub 2021 Jun 9.

Nuclear Medicine, University of Brescia and ASST Spedali Civili Brescia, Brescia, Italy.

Objectives: High-dose CT (HDCT) is considered the gold-standard imaging for the measurements of skeletal muscle area (SMA), visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT) and intramuscular adipose tissue (IMAT) areas in the abdomen. These parameters may reflect sarcopenia, which can have a prognostic impact in several oncological diseases. The aim of this study was to compare the agreement of measurements of SMA, VAT, SAT and IMAT areas between HDCT and low-dose CT (LDCT) of 18-fludeoxyglucose positron emission tomography (F-FDG PET)/CT in elderly patients affected by Hodgkin lymphoma (HL). Read More

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Cecal intubation time in screening colonoscopy.

Authors:
Hyun Young Kim

Medicine (Baltimore) 2021 May;100(19):e25927

Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea.

Abstract: The time required to intubate the cecum varies. The aim of this study was to determine whether demographic and anthropometric factors, such as body mass index (BMI), percent body fat, muscle mass, and fat mass, affect the cecal intubation time (CIT) during complete colonoscopy.A retrospective chart review of 1229 patients (aged 40-80 years) was performed. Read More

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Visceral adiposity and inflammatory bowel disease.

Int J Colorectal Dis 2021 Jun 9. Epub 2021 Jun 9.

Department of Gastroenterology, Beaumont Hospital, Beaumont Rd, Dublin, Ireland.

Background: Rates of obesity are increasing worldwide, as is the incidence of inflammatory bowel disease (IBD). Obesity is now considered an inflammatory state. Visceral adiposity in particular may be associated with a more severe inflammatory phenotype in IBD. Read More

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Malakoplakia mimicking a locally advanced colorectal neoplasm.

J Surg Case Rep 2021 Jun 4;2021(6):rjab225. Epub 2021 Jun 4.

Colorectal Surgery Unit, Surgery Service, Complejo Asistencial Doctor Sótero Del Río, Santiago 8207257, Chile.

Malakoplakia is a rare disease. Clinical presentation is non-specific, making its diagnosis an incidental finding on histopathological analysis. The aim of this case report is to describe a patient diagnosed with colon, renal and soft tissue malacoplakia mimicking a locally advanced colorectal cancer. Read More

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Erector spinae plane block: a new option for managing acute axial low back pain in the emergency department.

Pain Manag 2021 Jun 9. Epub 2021 Jun 9.

Department of Emergency Medicine, University of California San Diego, 200 West Arbor Drive, San Diego, CA 92103, USA.

To evaluate pain and length of stay outcomes in six patients who received an erector spinae plane block (ESPB) in the emergency department (ED) for low back pain. A case series of six patients who received unilateral or bilateral ESPB after presenting to the ED for acute atraumatic axial low back pain. The average visual analog scale pain score reduction was 81. Read More

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Atypical Polypoid Adenomyoma (APAM).

J Coll Physicians Surg Pak 2021 Jun;30(6):719-721

Department of Gynae Unit 1, Jinnah Hospital, Lahore, Pakistan.

Atypical polypoid adenomyoma (APAM) is a rare polypoidal benign tumor of uterus, which usually presents with irregular vaginal bleeding in women of reproductive age. It has the potential of malignant transformation but does not metastasise. It may coexist with endometrial hyperplasia and adenocarcinoma; and so, is usually misdiagnosed. Read More

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The role of estrogen in insulin resistance: a review of clinical and pre-clinical data.

Am J Pathol 2021 Jun 5. Epub 2021 Jun 5.

Thrombosis and Atherosclerosis Research Institute, , McMaster University, Hamilton, Ontario, Canada, 237 Barton Street East Hamilton, Ontario, Canada; Department of Medicine, McMaster University, Hamilton, Ontario, Canada, 237 Barton Street East Hamilton, Ontario, Canada. Electronic address:

Insulin resistance results when peripheral tissues, including adipose, skeletal muscle and liver, do not respond appropriately to insulin causing the ineffective uptake of glucose. This represents a risk factor for the development of type 2 diabetes mellitus. Along with abdominal obesity, hypertension, high levels of triglycerides, and low levels of high-density lipoproteins, insulin resistance is a component of a condition known as the metabolic syndrome, which significantly increases the risk of developing cardiometabolic disorders. Read More

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Ultrasound measurements of abdominal muscle thickness are associated with postmenstrual age at full oral feedings in preterm infants: A preliminary study.

Nutr Clin Pract 2021 Jun 8. Epub 2021 Jun 8.

Department of Pediatrics, University of Minnesota-Twin Cities, Minneapolis, Minnesota, USA.

Background: A premature infant's discharge from the neonatal intensive care unit (NICU) is dependent on factors such as respiratory stability, adequate growth, and the ability to consume oral feeds. Once infants have achieved respiratory stability, a tool that can better predict age at discharge is desirable. Thus, we conducted a secondary data analysis to assess the association between ultrasound measurements of abdominal muscle thickness and postmenstrual age (PMA) at full oral feedings. Read More

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What is the best method of rectovaginal fistula repair? A 25-year single-center experience.

Tech Coloproctol 2021 Jun 8. Epub 2021 Jun 8.

Division of Colon and Rectal Surgery, University of Illinois at Chicago, 840 S. Wood St., Suite 518E CSB (MC 958), Chicago, USA.

Background: The surgical treatment of rectovaginal fistula (RVF) remains challenging and there is a lack of data to demonstrate the best, single procedure. The aim of this study was to assess the results of different surgical operations for rectovaginal fistula.

Methods: Patients with RVF who underwent surgical repair between 1992 and 2017 at a single, tertiary care center were included. Read More

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[BCG-induced (bacillus Calmette-Guérin) abdominal granulomatosis after occult bladder perforation].

Urologe A 2021 Jun 8. Epub 2021 Jun 8.

Klinik für Urologie, Universitätsklinikum Tübingen, Hoppe-Seyler-Straße 3, 72076, Tübingen, Deutschland.

We present the case of a 57-year-old man who developed an intraperitoneal bladder fistula with BCG-induced (bacillus Calmette-Guérin) abdominal granulomatosis after transurethral resection of a papillary non-muscle invasive bladder cancer and subsequent BCG-instillation therapy. The bladder fistula was eliminated surgically. The detection of Mycobacterium tuberculosis in the operative sample drawings as well as the histological detection of BCG-granuloma led to specific treatment and a report to the responsible health department. Read More

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Metastases from renal cell carcinoma-Report of three unpredictable cases and literature review.

Indian J Cancer 2021 Apr-Jun;58(2):273-277

Department of Neurology, King George Medical University, Lucknow, Uttar Pradesh, India.

The capacity to metastasize after long periods of discovery and resection of the primary renal lesion or to present as metastasis with undisclosed primary lesions grant renal cell carcinomas (RCC) a formidable and unpredictable behavior. We report three unusual cases of metastasis from RCC. The first patient presented with metastatic clear cell adenocarcinoma in the right shoulder muscles, with unknown primary and revealed an undetected clear cell right RCC on radiology. Read More

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Ultrasound Measurement of the Transverse Abdominis, Internal Oblique, and External Oblique Muscles Associated with Forward Head Posture and Reduced Cranio-Vertebral Angle.

Med Sci Monit 2021 Jun 7;27:e928987. Epub 2021 Jun 7.

Department of Physical Therapy, College of Health Science, Cheongju University, Chungbuk, South Korea.

BACKGROUND Abnormal posture can affect the alignment of the cervical spine, which can lead to various physical problems. There are many ways to solve the problem by limiting the area around the neck to restore abnormal neck condition. However, there is a need to look at these problems from an enlarged perspective through the relationship between the cervical spine and trunk. Read More

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The performance of heparin modified poly(ε-caprolactone) small diameter tissue engineering vascular graft in canine-A long-term pilot experiment in vivo.

J Biomed Mater Res A 2021 Jun 7. Epub 2021 Jun 7.

School of Materials Science and Engineering, Beijing Institute of Technology, Beijing, China.

Long-term in vivo observation in large animal model is critical for evaluating the potential of small diameter tissue engineering vascular graft (SDTEVG) in clinical application, but is rarely reported. In this study, a SDTEVG is fabricated by the electrospinning of poly(ε-caprolactone) and subsequent heparin modification. SDTEVG is implanted into canine's abdominal aorta for 511 days in order to investigate its clinical feasibility. Read More

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A preliminary evaluation study of applying a deep learning image reconstruction algorithm in low-kilovolt scanning of upper abdomen.

J Xray Sci Technol 2021 Jun 3. Epub 2021 Jun 3.

GE Company, Beijing, China.

Objective: To investigate feasibility of applying deep learning image reconstruction (DLIR) algorithm in a low-kilovolt enhanced scan of the upper abdomen.

Methods: A total of 64 patients (BMI<28) are selected for the enhanced upper abdomen scan and divided evenly into two groups. The tube voltages in Group A are 100kV in arterial phase and 80kV in venous phase, while tube voltages are 120kV during two phases in Group B. Read More

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Prehabilitation program composed of blood flow restriction training and sports nutrition improves physical functions in abdominal cancer patients awaiting surgery.

Eur J Surg Oncol 2021 Jun 1. Epub 2021 Jun 1.

Department of Kinesiology and Health Education, USA. Electronic address:

Introduction: The impact of prehabilitation remains controversial due to a short presurgical waiting period and the diminished capacity of the patient population. A strategy to augment and optimize the effectiveness of prehabilitations for abdominal cancer patients may be found in the unlikely field of sport science. We investigated the use of blood flow restriction training and sport nutrition supplementation to augment functional capacity and increase muscle strength in twenty-four abdominal cancer patients awaiting surgery. Read More

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Abdominal Muscle Use during Spontaneous Breathing and Cough in Mechanically Ventilated Patients: a bi-center ultrasound study.

Chest 2021 Jun 3. Epub 2021 Jun 3.

Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada; Toronto General Hospital Research Institute, Toronto, Canada. Electronic address:

Background: Ultrasound may be useful to assess the structure, activity, and function of the abdominal muscles in mechanically ventilated patients.

Research Question: Does measurement of abdominal muscle thickening on ultrasound in mechanically ventilated patients provide clinically relevant information about abdominal muscle function and weaning outcomes?

Study Design And Methods: This study consisted of two parts, a physiological study conducted in healthy subjects and a prospective observational study in mechanically ventilated patients. Abdominal muscle thickness and thickening fraction (TF) were measured during cough and expiratory efforts in 20 healthy subjects and before and during a spontaneous breathing trial (SBT) in 57 ventilated patients. Read More

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Multidisciplinary consensus on nutritional and metabolic therapy in enhanced recovery after abdominal surgery programs: NutRICA Project.

Endocrinol Diabetes Nutr (Engl Ed) 2021 Jun 1. Epub 2021 Jun 1.

Unidad de Nutrición Clínica y Dietética, Hospital General Universitario Gregorio Marañón, Madrid, España.

Background: The Enhanced Recovery After Surgery (ERAS) care pathways include evidence-based items designed to accelerate recovery after surgery. Interdisciplinarity is one of the key points of ERAS programs.

Objective: To prepare a consensus document among the members of the Nutrition Area of the Spanish Society of Endocrinology and Nutrition (SEEN) and the Spanish Group for Multimodal Rehabilitation (GERM), in which the goal is to homogenize the nutritional and metabolic management of patients included in an ERAS program. Read More

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Woody breast myopathy broiler show age-dependent adaptive differential gene expression in Pectoralis major and altered in-vivo triglyceride kinetics in adipogenic tissues.

Poult Sci 2021 Mar 12;100(7):101092. Epub 2021 Mar 12.

Department of Poultry Science, Center of Excellence for Poultry Science, University of Arkansas, Fayetteville, AR 72701, USA. Electronic address:

A study was conducted to understand the differentially expressed genes in Pectoralis (P) major under woody breast (WB) myopathy condition in a high yielding broiler strain using RNA-sequencing at the growing (d 21) and finishing (d 42 and d 56) grow-out ages. Follow-up study was conducted to understand the in vivo triglyceride (TG) synthesis (d 49) occurring in adipogenic tissues using deuterium oxide (HO) as a metabolic tracer. Results indicated the top physiological systems affected in myopathy broiler were related to the musculo-skeletal system (d 21, 42, and 56) and cardiovascular system (d 42 and 56). Read More

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Expression analysis and single-nucleotide polymorphisms of and genes associated with thoracic vertebral numbers in sheep ().

Arch Anim Breed 2021 23;64(1):131-138. Epub 2021 Apr 23.

Key Laboratory of Animal Genetics and Breeding and Reproduction of the Ministry of Agriculture and Rural Affairs, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, P. R. China.

The objective of the current study was to analyze expression levels of synapse differentiation inducing 1-like () and unc-13 homolog C () genes in different tissues, while single-nucleotide polymorphisms (SNPs) of two genes were associated with multiple thoracic vertebrae traits in both Small-tailed Han sheep (STH) and Sunite sheep (SNT). The expression levels of and were analyzed in the brain, cerebellum, heart, liver, spleen, lung, kidney, adrenal gland, uterine horn, longissimus muscle, and abdominal adipose tissues of two sheep breeds with different thoracic vertebral number (TVN) sheep (T13 groups and T14 groups) by real-time quantitative polymerase chain reaction (RT-qPCR). Meanwhile, the polymorphisms of gene g. Read More

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Relationship between gait speed and trunk muscles in frail elderly individuals.

J Phys Ther Sci 2021 May 15;33(5):384-387. Epub 2021 May 15.

Department of Applied Biology, Kyoto Institute of Technology, Japan.

[Purpose] The external and internal abdominal muscles may be related to gait speed; however, this has not yet been elucidated. In this study, we aimed to clarify the relationship between gait speed and trunk muscle thickness in elderly individuals. [Participants and Methods] The participants were 12 elderly individuals (4 males and 8 females, mean age 83. Read More

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