24 results match your criteria aβ1-40

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Detection of association of IL1β, IL4R, and IL6 gene polymorphisms with cervical cancer in the Bangladeshi women by tetra-primer ARMS-PCR method.

Int Immunopharmacol 2021 Jan 10;90:107131. Epub 2020 Nov 10.

Department of Pharmacy, Noakhali Science and Technology University, Noakhali 3814, Bangladesh. Electronic address:

Background: Cervical cancer (CC) is the main cause of cancer-related deaths among women in developing countries. It is the second leading female malignancy in Bangladesh in terms of incidence and mortality. Our present study aimed to investigate the association of IL1β (rs16944), IL4R (rs1801275), and IL6 (rs1800797) gene polymorphisms with the susceptibility of cervical cancer. Read More

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January 2021

Survival following abdominal aortic aneurysm repair in North Queensland is not associated with remoteness of place of residence.

PLoS One 2020 13;15(11):e0241802. Epub 2020 Nov 13.

Queensland Research Centre for Peripheral Vascular Disease, College of Medicine and Dentistry, James Cook University, Townsville, Queensland, Australia.

Objective: To assess whether survival and clinical events following elective abdominal aortic aneurysm (AAA) repair were associated with remoteness of residence in North Queensland, Australia.

Methods: This retrospective cohort study included participants undergoing elective AAA repair between February 2002 and April 2020 at two hospitals in Townsville, North Queensland, Australia. Outcomes were all-cause survival and AAA-related events, defined as requirement for repeat AAA repair or AAA-related mortality. Read More

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January 2021

Disparities in mortality after abdominal aortic aneurysm repair are linked to insurance status.

J Vasc Surg 2020 11 12;72(5):1691-1700.e5. Epub 2020 Mar 12.

Department of Anesthesiology, Weill Cornell Medicine, New York, NY; Department of Anesthesiology, NewYork-Presbyterian Hospital, New York, NY. Electronic address:

Objective: The objective of this study was to determine differences in mortality after abdominal aortic aneurysm (AAA) repair based on insurance type.

Methods: In this retrospective cohort study, data from all-payer patients in nonpsychiatric hospitals in New York, Maryland, Florida, Kentucky, and California from January 2007 to December 2014 (excluding California, ending December 2011) were extracted from the State Inpatient Databases, Healthcare Cost and Utilization Project, Agency for Healthcare Research and Quality. There were 90,102 patients ≥18 years old with available insurance data who underwent open AAA repair or endovascular aneurysm repair (EVAR) identified using International Classification of Diseases, Ninth Revision, Clinical Modification procedure codes 3844, 3925, and 3971. Read More

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November 2020

The Effect of Left Renal Vein Division on Renal Function Following Open Abdominal Aortic Surgery Using Propensity Score Matching Analysis.

Ann Vasc Surg 2020 Jan 7;62:232-237. Epub 2019 May 7.

Division of Vascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea. Electronic address:

Background: Open surgery of abdominal aortic aneurysm (AAA) or aortoiliac occlusive disease (AIOD) sometimes requires left renal vein division (LRVD) to gain adequate exposure of the abdominal aorta. The aim of this study is to evaluate the effect of LRVD on the postoperative renal function using propensity score matching (PSM).

Methods: From July 1996 to January 2018, we retrospectively reviewed 698 patients who underwent open aortic surgery, including 543 AAAs and 155 AIODs, at a single institution. Read More

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January 2020

Sex differences in national rates of repair of emergency abdominal aortic aneurysm.

Br J Surg 2019 01 5;106(1):82-89. Epub 2018 Nov 5.

School of Health and Related Research, University of Sheffield, Sheffield, UK.

Background: The aim of this study was to assess the sex differences in both the rate and type of repair for emergency abdominal aortic aneurysm (AAA) in England.

Methods: Hospital Episode Statistics (HES) data sets from April 2002 to February 2015 were obtained. Clinical and administrative codes were used to identify patients who underwent primary emergency definitive repair of ruptured or intact AAA, and patients with a diagnosis of AAA who died in hospital without repair. Read More

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January 2019

Outcomes and cost of fenestrated versus standard endovascular repair of intact abdominal aortic aneurysm in the United States.

J Vasc Surg 2019 Apr 3;69(4):1036-1044.e1. Epub 2018 Oct 3.

Johns Hopkins Bayview Vascular and Endovascular Clinical Research Center, Baltimore, Md. Electronic address:

Background: Fenestrated endovascular aneurysm repair (FEVAR) has expanded the indications of this minimally invasive procedure to include patients with pararenal aneurysms. The actual cost of this relatively newer technology compared with standard endovascular aneurysm repair (EVAR) has not been studied before. Thus, the aim of this study was to analyze in-hospital costs and adverse outcomes in patients undergoing FEVAR vs EVAR for intact abdominal aortic aneurysms (AAAs). Read More

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Chronic kidney disease measures and the risk of abdominal aortic aneurysm.

Atherosclerosis 2018 12 1;279:107-113. Epub 2018 Sep 1.

University of Minnesota School of Public Health, Division of Epidemiology and Community Health, Minneapolis, MN, USA.

Background And Aims: Despite its strong link to cardiovascular outcomes, the association of chronic kidney disease (CKD) with abdominal aortic aneurysm (AAA) has not been explicitly and comprehensively investigated.

Methods: In 10,724 participants in the Atherosclerosis Risk in Communities Study (aged 53-75 years during 1996-1998), we evaluated the associations of two key CKD measures - estimated glomerular filtration rate (eGFR) and urine albumin-to-creatinine ratio (ACR) - with incident AAA (AAA diagnosis in outpatient, hospitalization discharge, or death records). Additionally, we performed a cross-sectional analysis for the CKD measures and ultrasound-based abdominal aortic diameter in 4258 participants during 2011-2013. Read More

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December 2018

Influence of Interhospital Transfer on Outcomes of Symptomatic and Ruptured Abdominal Aortic Aneurysms.

Rev Port Cir Cardiotorac Vasc 2017 Jul-Dec;24(3-4):110

Centro Hospitalar de Lisboa Central, Hospital de Santa Marta, Portugal.

Introduction: Symptomatic or ruptured abdominal aortic aneurysms (rAAA) maintains a high mortality index despite technical advances in its treatment. The influence of patients' geographic location on rAAA outcomes, when the rupture occurs or when the AAA becomes symptomatic, has not been a commonly studied issue. Due to the lack of research on this matter, the impact of interhospital transfer on mortality is ambiguous. Read More

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Lp-PLA activity and mass for prediction of incident abdominal aortic aneurysms: A prospective longitudinal cohort study.

Atherosclerosis 2017 07 21;262:14-18. Epub 2017 Apr 21.

Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden; Department of Heart Failure and Valvular Disease, Skåne University Hospital, Lund, Sweden.

Background And Aims: The pathogenesis of abdominal aortic aneurysm (AAA) shares several common pathways with atherosclerosis. Prospective clinical plasma biomarker studies in AAA have been hampered by the need for very large cohorts and long follow-up time.

Methods: We analyzed a prospective longitudinal cohort of middle-aged individuals from the cardiovascular cohort of the Malmö Diet and Cancer study (n = 5551; 1991-94). Read More

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Influence of interhospital transfer on outcomes of symptomatic and ruptured abdominal aortic aneurysms.

Rev Port Cir Cardiotorac Vasc 2017 Jan-Jun;24(1-2):29-31

Serviço de Angiologia e Cirurgia Vascular, Centro Hospitalar de Lisboa Central, Hospital de Santa Marta, Lisboa, Portugal.

Objetive: Evaluate the influence of the geographic location of patients with symptomatic abdominal aortic aneurysms (AAA) or ruptured AAA (rAAA), on mortality.

Methods: Retrospective review of all cases of symptomatic AAA and rAAA submitted to surgery in a tertiary institution, between January 2011 and August 2017. The main outcome was in-hospital mortality. Read More

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Association of 1166A>C ATR, -1562C>T MMP-9, ACE I/D, and CCR5Δ32 Polymorphisms with Abdominal Aortic Aneurysm in Croatian Patients.

Genet Test Mol Biomarkers 2016 Oct 17;20(10):616-623. Epub 2016 Aug 17.

4 Department of Biochemistry and Molecular Biology, Faculty of Pharmacy and Biochemistry, University of Zagreb , Zagreb, Croatia .

Aim: The purpose of this case-control study was to assess the association of abdominal aortic aneurysm (AAA) in Croatian patients with four genetic polymorphisms: SNP 1166A>C in the angiotensin II type 1 receptor gene (ATR); SNP -1562C>T in the matrix metalloproteinase-9 gene (MMP-9); the deletion of 32 bp in the chemokine receptor 5 gene (CCR5); and the insertion/deletion (I/D) of 287 bp in the angiotensin-converting enzyme gene (ACE).

Methods: Case-control study conducted with 117 patients with confirmed AAA (AAA) and 117 control subjects (AAA). Genotyping was performed using PCR or PCR-RFLP analysis. Read More

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October 2016

Sex-related Outcome Inequalities in Endovascular Aneurysm Repair.

Eur J Vasc Endovasc Surg 2016 Oct 29;52(4):518-525. Epub 2016 Aug 29.

Department of Vascular Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.

Objective/background: Women are known to have a higher rate of postoperative complications and mortality following open abdominal aortic aneurysm (AAA) repair. It is less clear whether this remains true of endovascular aneurysm repair (EVAR). This study examines the association between sex and hospital length of stay (LoS), readmission rates, and mortality following elective EVAR in the population of England between April 2006 and March 2015. Read More

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October 2016

Endovascular anatomic reconstruction of the iliac bifurcation with covered stentgrafts in sandwich-technique for the treatment of complex aorto-iliac aneurysms.

Int J Cardiol 2016 Nov 1;222:332-339. Epub 2016 Aug 1.

Clinic for Diagnostic and Interventional Radiology, Saarland University Medical Center, 66421 Homburg, Saar, Germany. Electronic address:

Objective: Endovascular anatomic reconstruction of iliac artery bifurcation in aorto-iliac aneurysms using commercial stentgrafts in sandwich-technique by bilateral transfemoral approach.

Methods: 24 patients (mean 73.8±standard deviation 6. Read More

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November 2016

Family history of atherosclerotic vascular disease is associated with the presence of abdominal aortic aneurysm.

Vasc Med 2016 Feb 12;21(1):41-6. Epub 2015 Nov 12.

Division of Cardiovascular Diseases and the Gonda Vascular Center, Mayo Clinic, Rochester, MN, USA

We investigated whether family history (FHx) of atherosclerotic cardiovascular disease (ASCVD) was associated with presence of abdominal aortic aneurysm (AAA). The study cohort comprised of 696 patients with AAA (70±8 years, 84% men) and 2686 controls (68±10 years, 61% men) recruited from noninvasive vascular and stress electrocardiogram (ECG) laboratories at Mayo Clinic. AAA was defined as a transverse diameter of abdominal aorta ⩾ 3 cm or history of AAA repair. Read More

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February 2016

Finite element analysis of abdominal aortic aneurysms: predicted rupture risk correlates with aortic wall histology in individual patients.

J Endovasc Ther 2014 Aug;21(4):556-64

1 Department of Vascular and Endovascular Surgery, Ruprecht-Karls University Heidelberg, Germany.

Purpose: To evaluate a finite element analysis (FEA) model as a predictive tool for abdominal aortic aneurysm (AAA) rupture risk assessment.

Methods: FEA of asymptomatic infrarenal AAAs in 15 men (mean age 72 years) was performed preoperatively using semiautomatic finite element analysis software (A4clinics) to calculate peak wall stress (PWS) and regions of highest and lowest rupture risk index (RRI). The areas of high and low RRI identified on the preoperative FEA were sampled during open surgery; aortic wall specimens were prepared for histological analysis. Read More

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Reasons for non-participation in population-based abdominal aortic aneurysm screening.

Br J Surg 2014 Apr 26;101(5):481-7. Epub 2014 Feb 26.

Section of Vascular Surgery, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden; Department of Clinical Science and Education, Karolinska Institutet at Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.

Background: A population-based screening programme for abdominal aortic aneurysm (AAA) started in 2010 in Stockholm County, Sweden. This present study used individual data from Sweden's extensive healthcare registries to identify the reasons for non-participation in the AAA screening programme.

Methods: All 65-year-old men in Stockholm are invited to screening for AAA; this study included all men invited from July 2010 to July 2012. Read More

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Antismooth muscle and antiactin antibodies are indirect markers of histological and biochemical activity of autoimmune hepatitis.

Hepatology 2014 Feb 20;59(2):592-600. Epub 2013 Dec 20.

Universidade Federal de Minas Gerais, Department of Internal Medicine, School of Medicine, Belo Horizonte, Minas Gerais, Brazil; Universidade Federal de Minas Gerais, University Hospital, Alfa Institute of Gastroenterology, Belo Horizonte, Minas Gerais, Brazil.

Unlabelled: Reactivity and titers of autoantibodies vary during the course of autoimmune hepatitis (AIH), and some autoantibodies have been associated with disease activity and adverse outcomes after treatment. The aim of this study was to assess the autoantibody behavior in AIH and its significance as predictors of biochemical and histological remission. A total of 117 patients with AIH (mean age 18. Read More

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February 2014

Exploration of the mechanisms by which 3,4-benzopyrene promotes angiotensin II-induced abdominal aortic aneurysm formation in mice.

J Vasc Surg 2014 Feb 12;59(2):492-9. Epub 2013 May 12.

Department of Cardiology, The Second Hospital Affiliated to Wenzhou Medical College, Wenzhou, China. Electronic address:

Objective: This study examined the influence of 3,4-benzopyrene (BaP), a compound found in cigarette smoke, on the formation of angiotensin II (Ang II)-induced abdominal aortic aneurysm (AAA) formation in mice and the underlying mechanisms.

Methods: C57/B6n mice were divided into four groups. The control group received a weekly intraperitoneal injection of medium-chain triglycerides. Read More

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February 2014

Prevalence of Peripheral Arterial Disease and Abdominal Aortic Aneurysm among Patients with Acute Coronary Syndrome.

Med J Malaysia 2013 ;68(1):10-2

Kuala Lumpur Hospital, General Surgery, Jalan Pahang, Kuala Lumpur, Federal Territory 50586, Malaysia.

Introduction: Peripheral arterial disease(PAD) and abdominal aortic aneurysm(AAA) are two important underdiagnosed vascular pathologies. As they share common risk factors with coronary arterial disease, we conducted a study to look at their prevalence among patients with acute coronary syndrome(ACS).

Materials And Methods: Patients with ACS admitted to Queen Elizabeth Hospital, Malaysia, from February 2009 till August 2009 were screened prospectively for PVD and AAA. Read More

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Acute kidney injury after abdominal aortic aneurysm surgery: detailed assessment of early effects using novel markers.

Pol Arch Med Wewn 2012 22;122(7-8):353-60. Epub 2012 Jun 22.

Department of Internal Medicine and Metabolic Diseases, Clinical Hospital No. 7, Medical University of Silesia, Upper Silesian Medical Center, Katowice, Poland.

Introduction:  One of the most severe complications of repair surgery for abdominal aortic aneurysms (AAA) is acute kidney injury (AKI). Even small rises in serum creatinine after surgery are associated with increased mortality.

Objectives:  The aim of the study was to assess the dynamics of AKI after elective AAA surgery using novel markers. Read More

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December 2012

What is the relationship between ¹⁸F-FDG aortic aneurysm uptake on PET/CT and future growth rate?

Eur J Nucl Med Mol Imaging 2011 Aug 6;38(8):1493-9. Epub 2011 Apr 6.

Department of Vascular Surgery, Brighton and Sussex University Hospital, Eastern Road, Brighton BN2 5BE, UK.

Purpose: In this study we investigate the relationship between (18)F-fluorodeoxyglucose (FDG) metabolism and future aneurysm expansion measured by serial duplex ultrasound. Current screening programmes are increasing the identification of patients with abdominal aortic aneurysm (AAA). The management of these patients remains challenging and methods of risk stratification are sought. Read More

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Serum secreted phospholipase A2 is associated with abdominal aortic aneurysm presence but not progression.

Atherosclerosis 2011 Jun 18;216(2):458-60. Epub 2011 Feb 18.

Vascular Biology Unit, School of Medicine and Dentistry, James Cook University, Townsville 4811, Australia.

Objective: Secretory phospholipase A(2) (sPLA(2)) has been implicated in rodent models of abdominal aortic aneurysm (AAA). The aim of this study was to assess whether serum sPLA(2) activity was associated with AAA presence and progression.

Methods: Serum sPLA(2) activity was measured using a fluorometric assay in 1002 men of whom 310 had an AAA. Read More

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Laparoscopic aortic surgery in obese patients.

Ann Vasc Surg 2009 Nov-Dec;23(6):717-21

Department of Vascular Surgery, Ambroise Paré University Hospital, Assistance Publique Hôpitaux de Paris, Boulogne-Billancourt, France.

Background: Our objective was to demonstrate the feasibility of laparoscopic abdominal aortic aneurysm (AAA) repair in obese patients and to confirm advantages observed with laparoscopic techniques in other surgical specialties regarding pulmonary and parietal complications in this population.

Methods: Between November 2000 and December 2007 we performed 37 laparoscopic aortic reconstructions in obese patients (body mass index [BMI] > 30 kg/m(2)). Median BMI was 31. Read More

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January 2010

The impact of gender on presentation, therapy, and mortality of abdominal aortic aneurysm in the United States, 2001-2004.

J Vasc Surg 2007 May 28;45(5):891-9. Epub 2007 Mar 28.

University of Massachusetts Medical School, Department of Surgery, Worcester, MA 01655, USA.

Introduction: The elective repair of abdominal aortic aneurysms (AAA) may decrease a patient's risk of rupture and confers a significantly lower in-hospital mortality rate than emergency repair. Previous works have shown that AAA rupture rates are higher in women compared to men, and that women have higher associated in-hospital mortality rates. This study was performed to evaluate, currently, to what extent patient gender influences presentation and treatment of AAA and the associated outcomes in the United States. Read More

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