6,232 results match your criteria Yersinia Enterocolitica


Bloodstream infection caused by Yersinia enterocolitica in a host with ankylosing spondylitis: a case report and literature review.

Ann Palliat Med 2020 Jul 8. Epub 2020 Jul 8.

Department of Pharmacy, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China.

The extraintestinal infections caused by Yersinia enterocolitica are very rare, especially in the form of spontaneous bloodstream infection at people without history of blood transfusion. Their clinical symptoms and treatments are still not very clear for now. Here, we report a case of spontaneous bloodstream infection caused by Y. Read More

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http://dx.doi.org/10.21037/apm-20-256DOI Listing

The Podovirus ϕ80-18 Targets the Pathogenic American Biotype 1B Strains of .

Front Microbiol 2020 19;11:1356. Epub 2020 Jun 19.

Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland.

We report here the complete genome sequence and characterization of bacteriophage vB_YenP_ϕ80-18. ϕ80-18 was isolated in 1991 using a serotype O:8 strain 8081 as a host from a sewage sample in Turku, Finland, and based on its morphological and genomic features is classified as a podovirus. The genome is 42 kb in size and has 325 bp direct terminal repeats characteristic for podoviruses. Read More

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http://dx.doi.org/10.3389/fmicb.2020.01356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316996PMC

Identification of a Novel Strain from Bats in Association with a Bat Die-Off That Occurred in Georgia (Caucasus).

Microorganisms 2020 Jul 4;8(7). Epub 2020 Jul 4.

KB One Health LLC, Fort Collins, CO 80523, USA.

is a bacterial species within the genus , mostly known as a human enteric pathogen, but also recognized as a zoonotic agent widespread in domestic pigs. Findings of this bacterium in wild animals are very limited. The current report presents results of the identification of cultures of from dead bats after a massive bat die-off in a cave in western Georgia. Read More

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http://dx.doi.org/10.3390/microorganisms8071000DOI Listing

Synthesis of Functionalized Magnetic Nanoparticles, Their Conjugation with the Siderophore Feroxamine and its Evaluation for Bacteria Detection.

J Vis Exp 2020 Jun 16(160). Epub 2020 Jun 16.

Centro de Investigacións Científicas Avanzadas (CICA), Departamento de Química, Facultade de Ciencias, Universidade da Coruña;

In the present work, the synthesis of magnetic nanoparticles, its coating with SiO2, followed by its amine functionalization with (3-aminopropyl)triethoxysilane (APTES) and its conjugation with deferoxamine, a siderophore recognized by Yersinia enterocolitica, using a succinyl moiety as a linker are described. Magnetic nanoparticles (MNP) of magnetite (Fe3O4) were prepared by solvothermal method and coated with SiO2 (MNP@SiO2) using the Stöber process followed by functionalization with APTES (MNP@SiO2@NH2). Then, feroxamine was conjugated with the MNP@SiO2@NH2 by carbodiimide coupling to give MNP@SiO2@NH2@Fa. Read More

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http://dx.doi.org/10.3791/60842DOI Listing

Application of data science in risk assessment and early warning.

EFSA J 2019 Sep 17;17(Suppl 2):e170908. Epub 2019 Sep 17.

The food supply chain has been recognised by the EU as a critical infrastructure, and its complexity is the main cause of vulnerability. Depending on the food matrix, natural and/or deliberate contamination, food-borne diseases or even food fraud incidents may occur worldwide. Consequently, robust predictive models and/or software tools are needed to support decision-making and mitigating risks in an efficient and timely manner. Read More

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http://dx.doi.org/10.2903/j.efsa.2019.e170908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015521PMC
September 2019

UPΦ phages, a new group of filamentous phages found in several members of .

Virus Evol 2020 Jan 22;6(1):veaa030. Epub 2020 Jun 22.

Department of Biology, Loyola University Chicago, 1032 W Sheridan Rd, Chicago, IL 60660, USA.

Filamentous phages establish chronic infections in their bacterial hosts, and new phages are secreted by infected bacteria for multiple generations, typically without causing host death. Often, these viruses integrate in their host's genome by co-opting the host's XerCD recombinase system. In several cases, these viruses also encode genes that increase bacterial virulence in plants and animals. Read More

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http://dx.doi.org/10.1093/ve/veaa030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307601PMC
January 2020

Biological properties of sea buckthorn (Hippophae rhamnoides L.) derived products.

Acta Sci Pol Technol Aliment 2020 Apr-Jun;19(2):195-205

Department of Fruit Growing, Viticulture and Enology, Slovak University of Agriculture in Nitra, Slovakia.

Background: Sea buckthorn is a good and possible source of a wide range of bioactive compounds with     a positive effect on the human body, especially polyphenols and carotenoids.

Methods: The present study aimed to evaluate the antioxidant and antimicrobial activities of Hippophae rhamnoides L. products - 100% oil, 100% juice, dry berries, and tea (dry berries, leaves, and twigs). Read More

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http://dx.doi.org/10.17306/J.AFS.0809DOI Listing

Vaccine Potential of a Recombinant Bivalent Fusion Protein LcrV-HSP70 Against Plague and Yersiniosis.

Front Immunol 2020 12;11:988. Epub 2020 Jun 12.

Microbiology Division, Defence Research and Development Establishment, Gwalior, India.

To counteract the deadly pathogens, i.e., , and , we prepared a recombinant DNA construct encoding the bivalent fusion protein LcrV-HSP70. Read More

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http://dx.doi.org/10.3389/fimmu.2020.00988DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303293PMC

The application research of xTAG GPP multiplex PCR in the diagnosis of persistent and chronic diarrhea in children.

BMC Pediatr 2020 Jun 26;20(1):309. Epub 2020 Jun 26.

Department of Gastroenterology, Children's Hospital of Nanjing Medical University, 72 Guangzhou Road, Nanjing, 210008, Jiangsu Province, China.

Background: Persistent and chronic diarrhea is difficult to treat, and infection is still the main cause. In this study, we investigate the application value of xTAG gastrointestinal pathogen panel (xTAG GPP) multiplex PCR in the early diagnosis of persistent and chronic diarrhea in children and to understand the epidemiology of intestinal diarrhea pathogens.

Methods: One hundred ninety-nine specimens were collected from Nanjing Children's Hospital Affiliated to Nanjing Medical University (Nanjing, China). Read More

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http://dx.doi.org/10.1186/s12887-020-02206-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318512PMC

Analysis of the Relationship of Microbial Contamination with Temperature and Cleaning Frequency and Method of Domestic Refrigerators in Japan.

J Food Prot 2020 Jul;83(7):1234-1240

Faculty of Agriculture, Kindai University, 3327-204, Nakamachi, Nara-shi, Nara 631-8505, Japan (ORCID: https://orcid.org/0000-0002-9651-9856 [M.M.]).

Abstract: Hygiene management of domestic refrigerators is an important aspect of food poisoning prevention. The aim of the present study was to confirm the relationship between microbial contamination and hygiene management by measuring microbial levels and investigating temperature and cleaning frequency and method of domestic refrigerators in Japan. We analyzed three internal sections (the egg compartment, bottom shelf, and vegetable drawer) of 100 domestic refrigerators in Japan. Read More

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http://dx.doi.org/10.4315/0362-028X.JFP-19-322DOI Listing

Exploring the genetic determinants underlying the differential production of an inducible chromosomal cephalosporinase - BlaB in Yersinia enterocolitica biotypes 1A, 1B, 2 and 4.

Sci Rep 2020 Jun 23;10(1):10167. Epub 2020 Jun 23.

Department of Microbiology, University of Delhi South Campus, New Delhi, 110021, India.

Yersinia enterocolitica is an enteric bacterium which can cause severe gastroenteritis. Beta-lactams are the most widely used antibiotics against Y. enterocolitica. Read More

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http://dx.doi.org/10.1038/s41598-020-67174-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311522PMC

A Lactococcus lactis-vectored oral vaccine induces protective immunity of mice against enterotoxigenic Escherichia coli lethal challenge.

Immunol Lett 2020 Jun 20;225:57-63. Epub 2020 Jun 20.

College of Veterinary Medicine, Northeast Agricultural University, Harbin, China. Electronic address:

Enterotoxigenic Escherichia coli (ETEC) is a global primary pathogenic bacterium causing diarrhoea in human and a wide variety of neonatal animals. Lactococcus lactis as non-pathogenic and food-grade lactic acid bacteria has already been explored as a vector for mucosal vaccine. Here, the current study was undertaken to evaluate the live recombinant L. Read More

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http://dx.doi.org/10.1016/j.imlet.2020.06.007DOI Listing

Associations of Yersinia enterocolitica infection with autoimmune thyroid diseases: a systematic review and meta-analysis.

Endocr Metab Immune Disord Drug Targets 2020 Jun 21. Epub 2020 Jun 21.

Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran. Iran.

Introduction: Yersinia enterocolitica infection is reportedly associated with the development of autoimmune thyroid diseases (AITD). However, evidence that such infection can lead to AITD is controversial. Thus, this study was aimed to investigate the associations of Y. Read More

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http://dx.doi.org/10.2174/1871530320666200621180515DOI Listing

COVID-19 presenting as severe, persistent abdominal pain and causing late respiratory compromise in a 33-year-old man.

BMJ Case Rep 2020 Jun 16;13(6). Epub 2020 Jun 16.

Department of Infection & Tropical Medicine, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.

A 33-year-old man presented repeatedly with severe abdominal pain and diarrhoea. Renal colic was suspected, and he was admitted for pain management. Questioning elicited an additional history of sore throat and mild, dry cough. Read More

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http://dx.doi.org/10.1136/bcr-2020-236030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299013PMC

The role of osmoregulated periplasmic glucans in the biofilm antibiotic resistance of Yersinia enterocolitica.

Microb Pathog 2020 May 31;147:104284. Epub 2020 May 31.

Beijing Laboratory for Food Quality and Safety, College of Food Science & Nutritional Engineering, China Agricultural University, Beijing, 100083, China. Electronic address:

The formation of biofilms by bacteria is of great significance because it involves many physiological changes that serve to protect the cells from various stresses. One of the best-known biofilm-specific properties of bacteria is that bacteria that grow in biofilms are generally more resistant to antibiotics than their planktonic counterparts. In a previous study, osmoregulated periplasmic glucans (OPGs), catalyzed by the opgGH operon, were identified and found to function in Rcs signalling in Yersinia enterocolitica. Read More

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http://dx.doi.org/10.1016/j.micpath.2020.104284DOI Listing

A Siloxane-Bridged Glycosyl Donor Enables Highly Stereoselective β-Xylulofuranosylation.

J Org Chem 2020 Jun 17. Epub 2020 Jun 17.

Department of Chemistry, University of Alberta, Edmonton, Alberta T6G 2G2, Canada.

We report a siloxane-protected donor () for the highly stereoselective formation of β-(2,3-)-xylulofuranosyl bonds. Glycosylation reactions with gave >80% yields, and only β-xylulofuranosides were isolated in all cases. The utility of for the synthesis of complex glycans was shown by its successful application to the preparation of the repeating unit from the lipopolysaccharide O-antigen of serovars O:5/O:5,27. Read More

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http://dx.doi.org/10.1021/acs.joc.0c01008DOI Listing

Transcriptomic analysis reveals the role of RcsB in suppressing bacterial chemotaxis, flagellar assembly and infection in Yersinia enterocolitica.

Curr Genet 2020 Jun 3. Epub 2020 Jun 3.

Beijing Laboratory for Food Quality and Safety, College of Food Science and Nutritional Engineering, China Agricultural University, 17 Qinghua East Rd., P.O. Box 398, Beijing, 100083, China.

Defining the Rcs (Regulator of Capsule Synthesis) regulon in Enterobacteriaceae has been the major focus of several recent studies. The overall role of the Rcs system in Yersinia enterocolitica is largely unknown. Our previous study showed that RcsB inhibits motility, biofilm formation and c-di-GMP production by negatively regulating flhDC, hmsHFRS and hmsT expression. Read More

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http://dx.doi.org/10.1007/s00294-020-01083-xDOI Listing

Proteomic analysis reveals the damaging role of low redox laccase from Yersinia enterocolitica strain 8081 in the midgut of Helicoverpa armigera.

Biotechnol Lett 2020 May 29. Epub 2020 May 29.

Laboratory of Enzymology and Recombinant DNA Technology, Department of Microbiology, Maharshi Dayanand University, Rohtak, Haryana, 124001, India.

Objective: Earlier, we have found that the enteropathogenic Yersinia enterocolitica have evolved the survival mechanisms that regulate the expression of laccase-encoding genes in the gut. The present study aims to characterize the purified recombinant laccase from Y. enterocolitica strain 8081 biovar 1B and understand its effect on the midgut of cotton bollworm, Helicoverpa armigera (Hübner) larvae. Read More

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http://dx.doi.org/10.1007/s10529-020-02925-xDOI Listing
May 2020
1.591 Impact Factor

Pemphigus foliaceus complicated by sepsis of the aetiology of after eating cheesecake.

Postepy Dermatol Alergol 2020 Feb 11;37(1):111-113. Epub 2018 Oct 11.

Department of Dermatology, Poznan University of Medical Sciences, Poznan, Poland.

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http://dx.doi.org/10.5114/ada.2018.78880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247066PMC
February 2020

Potential probiotic of Lactobacillus strains isolated from the intestinal tracts of pigs and feces of dogs with antibacterial activity against multidrug-resistant pathogenic bacteria.

Arch Microbiol 2020 May 23. Epub 2020 May 23.

Department of Entomology, College of Agriculture and Natural Resources, National Chung Hsing University, Taichung, Taiwan.

The occurrence of multidrug-resistant pathogenic bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA), multidrug-resistant Acinetobacter baumannii (MDRAB), extended-spectrum β-lactamase (ESBL) Escherichia coli, and Pseudomonas aeruginosa, has become a serious problem in animals and public. The objective of this study was to identify and isolate lactic acid bacterial (LAB) strains from the intestinal tracts of pigs and feces of dogs and then characterize them as potential probiotics with antimicrobial activity against multidrug-resistant pathogenic bacteria. In a preliminary isolation screening, 45 of 1167 isolated LAB strains were found to have anti-S. Read More

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http://dx.doi.org/10.1007/s00203-020-01908-wDOI Listing

Isolation and identification of potential probiotic Lactobacillus species from feces of infants in southwest Iran.

Int J Infect Dis 2020 May 18. Epub 2020 May 18.

Abuzar Children's Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; Alimentary Tract Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Electronic address:

Objectives: To evaluate the potential probiotic properties ofLactobacillus strains isolated from feces of infants and also to determine their antimicrobial activity against some enteropathogenic bacteria.

Methods: The Fecal samples were prepared from 120 infants aged less than 24 months. In total,105 Lactobacillus strains were identified by phenotypic tests. Read More

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http://dx.doi.org/10.1016/j.ijid.2020.05.034DOI Listing
May 2020
2.330 Impact Factor

Evaluation of Reactivity of Monoclonal Antibodies Against Omp25 of spp.

Front Cell Infect Microbiol 2020 21;10:145. Epub 2020 Apr 21.

Department of Transfusion Medicine, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.

Brucellosis is a serious zoonosis occurring mainly in developing countries, and its diagnosis is largely dependent on serologic detection and bacterial culture. In this study, we developed the murine monoclonal antibodies (mAbs) against a conserved and major outer membrane protein 25 (Omp25) of species (. spp. Read More

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http://dx.doi.org/10.3389/fcimb.2020.00145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187720PMC

UV-C Irradiation of Rolled Fillets of Ham Inoculated with and .

Foods 2020 May 1;9(5). Epub 2020 May 1.

Institute for Food Quality and Food Safety, Foundation University of Veterinary Medicine Hannover, Bischofsholer Damm 15, 30173 Hannover, Germany.

Bacteria on ready-to-eat meat may cause diseases and lead to faster deterioration of the product. In this study, ready-to-eat sliced ham samples were inoculated with or and treated with ultraviolet (UV) light. The initial effect of a UV-C irradiation was investigated with doses of 408, 2040, 4080, and 6120 mJ/cm and the effect after 0, 7, and 14 days of refrigerated storage with doses of 408 and 4080 mJ/cm. Read More

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http://dx.doi.org/10.3390/foods9050552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278610PMC

Purification and characterization of a novel trypsin inhibitor from Solanum tuberosum subsp. andigenum var. overa: Study of the expression levels and preliminary evaluation of its antimicrobial activity.

Int J Biol Macromol 2020 Apr 28. Epub 2020 Apr 28.

Centro de Investigación de Proteínas Vegetales (CIProVe), Departamento de Ciencias Biológicas, Facultad de Ciencias Exactas, Universidad Nacional de la Plata, 47 y 115s/N, B1900AVW La Plata, Buenos Aires, Argentina. Electronic address:

Protease inhibitors (PIs) have been traditionally recognized by their potential biomedical application in events with exacerbation of endogenous proteases activity. Plant PIs have gained interest as naturally occurring molecules, which usually show lower environmental impact residual toxicity than synthetic compounds. In this work, we isolated, cloned, expressed and purified a novel trypsin inhibitor from S. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2020.04.217DOI Listing

The Prevalence of and in Small Wild Rodents in Poland.

Vector Borne Zoonotic Dis 2020 Apr 28. Epub 2020 Apr 28.

Department of Epizootiology, Faculty of Veterinary Medicine, University of Warmia and Mazury, Olsztyn, Poland.

Rodents are a large group of mammals that can be carriers of zoonotic pathogens such as strains that cause yersiniosis. The prevalence of and was determined in 214 small wild rodents from south-eastern Poland. Samples were analyzed by precultivation and PCR. Read More

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http://dx.doi.org/10.1089/vbz.2019.2586DOI Listing

Urease Expression in Pathogenic Strains of Bio-Serotypes 2/O:9 and 1B/O:8 Is Differentially Regulated by the OmpR Regulator.

Front Microbiol 2020 8;11:607. Epub 2020 Apr 8.

Department of Molecular Microbiology, Institute of Microbiology, Faculty of Biology, University of Warsaw, Warsaw, Poland.

exhibits a dual lifestyle, existing as both a saprophyte and a pathogen colonizing different niches within a host organism. OmpR has been recognized as a regulator that controls the expression of genes involved in many different cellular processes and the virulence of pathogenic bacteria. Here, we have examined the influence of OmpR and varying temperature (26°C vs. Read More

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http://dx.doi.org/10.3389/fmicb.2020.00607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156557PMC

[Comparing traditional and commercial molecular biology detection of gastrointestinal pathogens with AusDiagnostics panels in Motol University Hospital].

Klin Mikrobiol Infekc Lek 2019 Dec;25(4):132-139

Department of Medical Microbiology, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Czech Republic, e-mail:

Background: The aim was to do an internal audit of gastrointestinal pathogen detection at the Department of Medical Microbiology, Motol University Hospital between the years 2014 and 2018 and to test two commercial multiplex molecular biology assays potentially improving the diagnostic process and reducing costs.

Material And Methods: Based on data from a laboratory information system (LIS), a total of 45,888 samples were identified which had been tested for the presence of gastrointestinal pathogens using culture, immunochromatographic, microscopic and molecular biology techniques between 2014-2018. Novel multiplex molecular biology detection was used to test 182 nucleic acid isolates obtained from stool samples with the Enteric Viruses (8-well) assay (Viral Panel, EVP) or Faecal Pathogens M (16-well) assay (Microbial Panel, FPM) manufactured by AusDiagnostics. Read More

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December 2019

Aporphinoid alkaloids inhibit biofilm formation of Yersinia enterocolitica isolated from sausages.

J Appl Microbiol 2020 Apr 12. Epub 2020 Apr 12.

Instituto Multidisciplinario de Investigaciones Biológicas de San Luis-Consejo Nacional de Investigaciones Científicas y Técnicas (IMIBIO-SL-CONICET), San Luis, Argentina.

Aims Of The Study: The ability of Yersinia enterocolitica strains to form biofilms and the capacity of different alkaloids to inhibit biofilm formation were investigated.

Methods And Results: The capacity to form biofilm on polystyrene of 31 Y. enterocolitica strains was evaluated. Read More

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http://dx.doi.org/10.1111/jam.14664DOI Listing

Synthesis of 5-Aminolevulinic Acid-Based ALACELL Possessing Inhibitory Effect against : Whitening Effect and Protective Effect of UVB-Irradiated Damage Cells.

J Cosmet Sci 2020 Mar/Apirl;71(2):65-76

Department of Pharmaceutical Engineering, Dongshin University, Jeonnam, 58245 South Korea (H.-Y.K., S.-H.Y.), School of Biological Sciences and Biotechnology Graduate School, Chonnam National University, Gwangju, 61186 South Korea (S.-J.K.), Department of Beauty Science, Kwangju Women's University, Gwangju 62396, South Korea (H.-J.C.).

Five-aminolevulinic acid (5-ALA)-photodynamic therapy combined with infrared radiation is an effective and safe therapy for facial acne. Although there are various available agents for treating acne, therapies for resistant or severe strains have been limited. The aim of this study was to investigate the inhibitory efficacy of ALACELL synthesized by combining 5-ALA with Y-G-G-F-L peptide against , , , and , as well as . Read More

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Bioserotypes, Virulence Markers, and Antimicrobial Susceptibility of Strains Isolated from Free-Living Birds.

Biomed Res Int 2020 17;2020:8936591. Epub 2020 Mar 17.

Department of Epizootiology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Poland.

The risk of meat contamination with poses a threat to consumers and persons who come into contact with bird carcasses. The occurrence of . in the vast majority of migratory game species, the capercaillie, and the black grouse has never been studied in Poland, Europe, or in the world. Read More

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http://dx.doi.org/10.1155/2020/8936591DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103032PMC

Use of meat juice and blood serum with a miniaturised protein microarray assay to develop a multi-parameter IgG screening test with high sample throughput potential for slaughtering pigs.

BMC Vet Res 2020 Apr 6;16(1):106. Epub 2020 Apr 6.

Institute of Food Safety and Food Hygiene, Section Meat Hygiene, Freie Universität Berlin, Königsweg 67, D-14163, Berlin, Germany.

Background: Serological screening of pig herds at the abattoir is considered a potential tool to improve meat inspection procedures and herd health management. Therefore, we previously reported the feasibility of a miniaturised protein microarray as a new serological IgG screening test for zoonotic agents and production diseases in pigs. The present study investigates whether the protein microarray-based assay is applicable for high sample throughput using either blood serum or meat juice. Read More

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http://dx.doi.org/10.1186/s12917-020-02308-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137480PMC

Application of an -Linked Glycosylation System in Serotype O:9 to Generate a New Candidate Vaccine against .

Microorganisms 2020 Mar 20;8(3). Epub 2020 Mar 20.

State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Biotechnology, 20 Dongdajie Street, Fengtai, Beijing 100071, China.

Brucellosis is a major zoonotic public health threat worldwide, causing veterinary morbidity and major economic losses in endemic regions. However, no efficacious brucellosis vaccine is yet available, and live attenuated vaccines commonly used in animals can cause human infection. - and -linked glycosylation systems have been successfully developed and exploited for the production of successful bioconjugate vaccines. Read More

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http://dx.doi.org/10.3390/microorganisms8030436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7143757PMC

CLONAL SPREAD OF 1B/O:8 IN MULTIPLE ZOO SPECIES.

J Zoo Wildl Med 2020 Mar;51(1):170-176

University Nebraska Medical Center, 985900 Nebraska Medical Center, Omaha, Nebraska 68198-5900, USA.

(YE) bioserotype 1B/O:8 (YE 1B/O:8) was identified in routine culture of a variety of zoo species housed at Omaha's Henry Doorly Zoo and Aquarium (OHDZA) from April to July 2011. Animal cases representing 12 species had YE detected from 34 cases during routine fecal monitoring and/or during postmortem examination: Coquerel's sifakas (, two cases), black & white (BW) ruffed lemurs (, six cases), red ruffed lemurs (, seven cases), white handed gibbon one case), black lemurs ( three cases), mongoose lemurs (, two cases), African hunting dogs (, five cases), agile gibbons (, three cases), siamangs (, two cases), colobus monkey (, one case), argus pheasant (, one case), and orangutan (, one case). Most species were not symptomatic; however, three symptomatic cases in Coquerel's sifakas (two) and a white handed gibbon (one) showed clinical signs of diarrhea and lethargy that resulted in death for the Coquerel's sifakas. Read More

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http://dx.doi.org/10.1638/2019-0062DOI Listing

The Yersinia Phage X1 Administered Orally Efficiently Protects a Murine Chronic Enteritis Model Against Infection.

Front Microbiol 2020 6;11:351. Epub 2020 Mar 6.

Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.

is generally considered an important food-borne pathogen worldwide, especially in the European Union. A lytic Yersinia phage X1 (Viruses; dsDNA viruses, no RNA stage; Caudovirales; and Myoviridae) was isolated. Phage X1 showed a broad host range and could effectively lyse 27/51 strains covering various serotypes that cause yersiniosis in humans and animals (such as serotype O3 and serotype O8). Read More

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http://dx.doi.org/10.3389/fmicb.2020.00351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067902PMC

[Terminal ileitis due to Yersinia enterocolitica: differential diagnosis with Crohn´s disease in a 12-year-old male].

Arch Argent Pediatr 2020 04;118(2):e191-e193

Servicio de Gastroenterología, Hepatología y Nutrición, Sanatorio de Niños, Rosario, Santa Fe, Argentina.

Yersinia enterocolitica is a gram-negative rod causing intestinal infection in humans. It shows different clinical pictures with many different etiologies to be ruled-out, which sometimes makes it difficult to reach a timely and correct diagnosis. We report the case of an adolescent boy presenting with right lower quadrant pain from terminal ileitis with endoscopic findings akin to Crohn´s disease finally diagnosed as Yersinia enterocolitica, highlighting the usefulness of the different ancillary methods employed. Read More

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http://dx.doi.org/10.5546/aap.2020.e191DOI Listing

Animal agriculture exposures among Minnesota residents with zoonotic enteric infections, 2012-2016.

Epidemiol Infect 2020 03 16;148:e55. Epub 2020 Mar 16.

Foodborne, Waterborne, Vectorborne, and Zoonotic Diseases Section, Infectious Disease Epidemiology, Prevention and Control Division, Minnesota Department of Health, St. Paul, MN, USA.

Prospective, population-based surveillance to systematically ascertain exposures to food production animals or their environments among Minnesota residents with sporadic, domestically acquired, laboratory-confirmed enteric zoonotic pathogen infections was conducted from 2012 through 2016. Twenty-three percent (n = 1708) of the 7560 enteric disease cases in the study reported an animal agriculture exposure in their incubation period, including 60% (344/571) of Cryptosporidium parvum cases, 28% (934/3391) of Campylobacter cases, 22% (85/383) of Shiga toxin-producing Escherichia coli (STEC) O157 cases, 16% (83/521) of non-O157 STEC cases, 10% (253/2575) of non-typhoidal Salmonella enterica cases and 8% (9/119) of Yersinia enterocolitica cases. Living and/or working on a farm accounted for 61% of cases with an agricultural exposure, followed by visiting a private farm (29% of cases) and visiting a public animal agriculture venue (10% of cases). Read More

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http://dx.doi.org/10.1017/S0950268819002309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078579PMC

sp. nov., isolated from a human yersiniosis case.

Int J Syst Evol Microbiol 2020 Apr 11;70(4):2382-2387. Epub 2020 Mar 11.

UCD-Centre for Food Safety, School of Public Health, Physiotherapy & Sports Science, University College Dublin, Belfield, Dublin D04 N2E5, Ireland.

A Gram-negative rod from the genus was isolated from a clinical case of yersiniosis in the United Kingdom. Long read sequencing data from an Oxford Nanopore Technologies (ONT) MinION in conjunction with Illumina HiSeq reads were used to generate a finished quality genome of this strain. Overall Genome Related Index (OGRI) of the strain was used to determine that it was a novel species within , despite biochemical similarities to . Read More

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http://dx.doi.org/10.1099/ijsem.0.004047DOI Listing

Comparison of several Real-Time PCR Kits versus a Culture-dependent Algorithm to Identify Enteropathogens in Stool Samples.

Sci Rep 2020 Mar 9;10(1):4301. Epub 2020 Mar 9.

Facultad de Medicina, Universidad de Zaragoza, Zaragoza, Spain.

This study aims to validate the current diagnostic method for the clinical detection of gastroenteritis. We analyzed 400 stool samples to detect three of the most common enteropathogens: Salmonella spp., Campylobacter spp. Read More

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http://dx.doi.org/10.1038/s41598-020-61202-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062723PMC

β-Selective xylulofuranosylation via a conformationally-restricted glycosyl donor.

Org Biomol Chem 2020 03;18(12):2264-2273

Department of Chemistry, University of Alberta, Edmonton, Alberta, CanadaT6G 2G2.

Reported is the first stereoselective method for β-xylulofuranosylation, which employs 3,4-O-xylylene-protected thioglycoside donors. For most acceptors, the best results were observed with a donor (8) that possesses both the xylylene group and a benzoate ester at O-1. To demonstrate its utility, the methodology was applied to the first synthesis of the pentasaccharide repeating unit from the lipopolysaccharide O-antigen of Yersinia enterocolitica serovars O:5/O:5,27, a structure containing two β-xylulofuranose residues. Read More

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http://dx.doi.org/10.1039/d0ob00260gDOI Listing

Bacterial Infection Allows for Functional Examination of Adoptively Transferred Mouse Innate Lymphoid Cell Subsets.

Methods Mol Biol 2020 ;2121:129-140

Division of Developmental Immunology, La Jolla Institute for Immunology, La Jolla, CA, USA.

Innate lymphoid cells (ILCs) are important regulators of the early responses to infection at mucosal barriers, including the intestine. Recently, we have shown that specific ILC3 subsets protect against enteric bacterial pathogens. Here, we describe a mouse model of oral infection by Yersinia enterocolitica (Y. Read More

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http://dx.doi.org/10.1007/978-1-0716-0338-3_12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7234820PMC
January 2020

Characterization of the main immunogenic proteins in Brucella infection for their application in diagnosis of brucellosis.

Comp Immunol Microbiol Infect Dis 2020 Jun 29;70:101462. Epub 2020 Feb 29.

Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences (CAAS), Shanghai, 200241, China. Electronic address:

Brucellosis is an important zoonotic bacterial disease widespread in the world. The key step of control this disease is accurate diagnosis and elimination of diseased animals. The classic diagnostic methods, such as tube agglutination test, are inaccurate and nonspecific, because of cross-reaction with Yersinia enterocolitica serotype O:9. Read More

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http://dx.doi.org/10.1016/j.cimid.2020.101462DOI Listing

Dendritic Cells of Mesenteric and Regional Lymph Nodes Contribute to O:3-Induced Reactive Arthritis in Mice.

J Immunol 2020 Apr 2;204(7):1859-1868. Epub 2020 Mar 2.

Facultad de Química, Bioquímica y Farmacia, Universidad Nacional de San Luis, 5700 San Luis, Argentina; and

Dendritic cells (DCs) participate in the pathogenesis of several diseases. We investigated DCs and the connection between mucosa and joints in a murine model of O:3-induced reactive arthritis (ReA) in mice. DCs of mesenteric lymph nodes (MLN) and joint regional lymph nodes (RLN) were analyzed in and wild-type mice. Read More

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http://dx.doi.org/10.4049/jimmunol.1901137DOI Listing

Yersinia enterocolitica-specific modulation of innate immune responses in jejunal epithelial cells.

Vet Microbiol 2020 Mar 24;242:108596. Epub 2020 Jan 24.

Laboratory of Animal Welfare, Clinical Chemistry and Veterinary Immunology, Istituto Zooprofilattico Sperimentale Della Lombardia e Dell'Emilia-Romagna, via A. Bianchi 9, 25124, Brescia, Italy. Electronic address:

Gut is often subject to infection by different pathogens like Y. enterocolitica. To date, biotypes (BTs) 1A have been considered as non-pathogenic, because they do not express plasmid of virulence pYV; however, BTs 1A strains present other chromosomic virulence genes and recent studies suggest an implication of this microorganism in reactive arthritis. Read More

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http://dx.doi.org/10.1016/j.vetmic.2020.108596DOI Listing
March 2020
2.511 Impact Factor

Osmoregulated Periplasmic Glucans Transmit External Signals Through Rcs Phosphorelay Pathway in .

Front Microbiol 2020 5;11:122. Epub 2020 Feb 5.

Beijing Laboratory for Food Quality and Safety, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing, China.

Fast response to environmental changes plays a key role in the transmission and pathogenesis of . Osmoregulated periplasmic glucans (OPGs) are known to be involved in environmental perception of several pathogens; however, the biological function of OPGs in is still unclear. In this study, we investigated the role of OPGs in by deleting the operon encoding enzymes responsible for OPGs biosynthesis. Read More

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http://dx.doi.org/10.3389/fmicb.2020.00122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013093PMC
February 2020

Evaluation of the efficacy of commonly used disinfectants against isolated chlorine-resistant strains from drinking water used in Egyptian cattle farms.

Vet World 2019 Dec 21;12(12):2025-2035. Epub 2019 Dec 21.

Department of Microbiology, Faculty of Veterinary Medicine, Cairo University, Giza 11221, Egypt.

Background And Aim: Drinking water of poor microbiological quality contains high percentages of microbes causing outbreaks of mainly coliform-related diseases. These microbes could be controlled by many hygienic standards including disinfection, but disinfectants misuse causes the developing of disinfectant-resistant strains. The present study aimed to investigate drinking water bacterial profile, determine chlorine-resistant strains, and statistically correlate that with the used disinfectant and disinfection process variables. Read More

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http://dx.doi.org/10.14202/vetworld.2019.2025-2035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989312PMC
December 2019

Yersinia enterocolitica Infection Presenting as Incomplete Kawasaki Disease: 2 Cases and a Review of the Literature.

J Pediatric Infect Dis Soc 2020 Feb 21. Epub 2020 Feb 21.

Department of Pediatrics, State University of New York Upstate Medical University, Syracuse, New York, USA.

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http://dx.doi.org/10.1093/jpids/piaa016DOI Listing
February 2020

Comparative in-silico proteomic analysis discerns potential granuloma proteins of Yersinia pseudotuberculosis.

Sci Rep 2020 Feb 20;10(1):3036. Epub 2020 Feb 20.

Department of Biophysics, University of Delhi South Campus, New Delhi, 110021, India.

Yersinia pseudotuberculosis is one of the three pathogenic species of the genus Yersinia. Most studies regarding pathogenesis of Y. pseudotuberculosis are based on the proteins related to Type III secretion system, which is a well-known primary virulence factor in pathogenic Gram-negative bacteria, including Y. Read More

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http://dx.doi.org/10.1038/s41598-020-59924-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033130PMC
February 2020
5.078 Impact Factor

High seroprevalence of pathogenic Yersinia spp. in sheep and goats across nine government farms in the Pakistani Punjab.

J Infect Dev Ctries 2019 09 30;13(9):843-846. Epub 2019 Sep 30.

Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Institute of Bacterial Infections and Zoonoses, Naumburger, Jena, Germany.

Introduction: Seroprevalence of Y. enterocolitica and Y. pseudotuberculosis infections in animals and humans is not established in Pakistan. Read More

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http://dx.doi.org/10.3855/jidc.11289DOI Listing
September 2019

Isolate Specific Cold Response of in Transcriptional, Proteomic, and Membrane Physiological Changes.

Front Microbiol 2019 23;10:3037. Epub 2020 Jan 23.

Institute of Food Safety and Food Hygiene, Department of Veterinary Medicine, Freie Universität Berlin, Berlin, Germany.

, a zoonotic foodborne pathogen, is able to withstand low temperatures. This psychrotrophic ability allows it to multiply in food stored in refrigerators. However, little is known about the cold response. Read More

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http://dx.doi.org/10.3389/fmicb.2019.03037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990146PMC
January 2020