4,842 results match your criteria Wrist Arthritis


ERAMRS: a new MR scoring system for early rheumatoid arthritis of the wrist.

Eur Radiol 2019 Mar 14. Epub 2019 Mar 14.

Department of Medicine & Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, 30-32 Ngan Shing Street, Shatin, N.T., Hong Kong.

Purpose: To (i) devise a new semi-quantitative scoring system known as Early Rheumatoid Arthritis Magnetic Resonance Score (ERAMRS) to assess inflammation of the wrist on magnetic resonance imaging in early rheumatoid arthritis and to (ii) test ERAMRS and other MR scoring systems against everyday used clinical scorings.

Materials And Methods: One hundred six treatment-naïve patients (81 females, 25 males, mean age 53 ± 12 years) with early rheumatoid arthritis (ERA) underwent clinical/serological testing as well as 3-T MRI examination of the most symptomatic wrist. Clinical assessment included Disease Activity Score-28 and Health Assessment Questionnaire; erythrocyte sedimentation rate and C-reactive protein were measured. Read More

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http://dx.doi.org/10.1007/s00330-019-06060-8DOI Listing
March 2019
1 Read

Correlation between systemic osteoporosis and local bone erosion with rheumatoid arthritis patients in Chinese population.

Rheumatology (Oxford) 2019 Mar 7. Epub 2019 Mar 7.

Institute of Clinical pharmacology, Anhui Medical University.

Objective: RA is a systemic auto-immune inflammatory disease that can lead to local bone erosions and generalized osteoporosis (OP). The aim of this study was to investigate the relationship between systemic osteoporosis and local bone erosion with RA patients in the Chinese population.

Methods: In total, 1235 patients with RA and 158 normal subjects were enrolled in this study. Read More

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https://academic.oup.com/rheumatology/advance-article/doi/10
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http://dx.doi.org/10.1093/rheumatology/kez042DOI Listing
March 2019
2 Reads

Effect of Alendronic Acid on Fracture Healing: A Multicenter Randomized Placebo-Controlled Trial.

J Bone Miner Res 2019 Mar 7. Epub 2019 Mar 7.

Edinburgh Clinical Trials Unit, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.

There is a concern that bisphosphonates may impair fracture healing because of their inhibitory effects on bone turnover. Here we evaluated the effects of early bisphosphonate therapy on fracture healing and functional outcome following a fracture of the distal radius. The fracture and bisphosphonates (FAB) trial was a double-blind, randomized, placebo-controlled trial involving 15 trauma centers in the United Kingdom. Read More

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http://dx.doi.org/10.1002/jbmr.3679DOI Listing
March 2019
4 Reads
6.832 Impact Factor

Power-Doppler perfusion phenotype in RA patients is dependent on anti-citrullinated peptide antibody status, not on rheumatoid factor.

Rheumatol Int 2019 Feb 26. Epub 2019 Feb 26.

Department of Rheumatology, Medical Clinic II, University Clinic Würzburg, Oberduerrbacher Str. 6, 97080, Würzburg, Germany.

It is not known whether there are any consistent non-serological differences between seropositive and seronegative rheumatoid arthritis, and if any, whether they depend upon rheumatoid factor (RF), anti-citrullinated peptide antibodies (ACPA), or both. In a pilot study, we showed that the two forms could be differentiated using power-Doppler sonography (PDS), and that the difference is ACPA dependent. This extended study explored whether the previous findings could be confirmed. Read More

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http://dx.doi.org/10.1007/s00296-019-04256-1DOI Listing
February 2019
1 Read

Technique of Tendon Interposition Arthroplasty for Chronic Volar Dislocation of the Distal Radioulnar Joint.

J Hand Surg Am 2019 Feb 22. Epub 2019 Feb 22.

Case Western Reserve University School of Medicine, Cleveland, OH. Electronic address:

Volar distal radioulnar joint (DRUJ) dislocations are uncommon wrist injuries. Failed diagnosis or treatment can result in irreversible damage to the articulating surfaces and ultimately lead to chronic degenerative arthritis. When the DRUJ is reducible, and the cartilage is preserved, ligament reconstruction and ulnar osteotomy are surgical options for residual wrist instability or pain. Read More

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http://dx.doi.org/10.1016/j.jhsa.2019.01.007DOI Listing
February 2019
1 Read

Factors Associated With the Cost of Care for the Most Common Atraumatic Painful Upper Extremity Conditions.

J Hand Surg Am 2019 Feb 16. Epub 2019 Feb 16.

Department of Internal Medicine, Dell Medical School, The University of Texas at Austin, Austin, TX.

Purpose: To help strategize efforts to optimize value (relative improvement in health for resources invested), we analyzed the factors associated with the cost of care and use of resources for painful, nontraumatic conditions of the upper extremity.

Methods: The following were the most common upper extremity diagnoses in the Truven Health MarketScan database: shoulder pain and rotator cuff tendinopathy, shoulder stiffness, shoulder arthritis, lateral epicondylitis, hand arthritis, trigger finger, wrist pain, and hand pain. Multivariable generalized linear regression models were constructed accounting for sex, age, employment status, enrollment year, payer type, emergency room visit, joint injection, magnetic resonance imaging (MRI), physical or occupational therapy, outpatient and inpatient surgery, and insurance type. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03635023183050
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http://dx.doi.org/10.1016/j.jhsa.2019.01.001DOI Listing
February 2019
3 Reads

Evaluation of the PROMIS Upper Extremity Computer Adaptive Test Against Validated Patient-Reported Outcomes in Patients With Basilar Thumb Arthritis.

J Hand Surg Am 2019 Feb 15. Epub 2019 Feb 15.

Department of Orthopaedic Surgery, Thomas Jefferson University; and the Rothman Institute, Philadelphia, PA. Electronic address:

Purpose: The Patient-Reported Outcomes Measurement Information System (PROMIS) Upper Extremity (UE) computer adaptive test was developed to reduce test burden and improve precision. We hypothesized that, in patients with thumb basilar joint arthritis (BJA), (1) PROMIS UE would correlate with established patient-outcomes (PROs), (2) PROMIS UE would require less time and fewer questions than current metrics, (3) there would be no floor or ceiling effects, and (4) PROMIS UE would not correlate with radiographic disease severity.

Methods: Patients presenting with a primary diagnosis of thumb BJA completed the Quick Disabilities of the Arm Shoulder and Hand (QuickDASH), Thumb Disability Examination (TDX), Patient-Rated Wrist Hand Evaluation (PRWHE), and PROMIS UE. Read More

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http://dx.doi.org/10.1016/j.jhsa.2019.01.003DOI Listing
February 2019
3 Reads

What is the additional value of MRI of the foot to the hand in undifferentiated arthritis to predict rheumatoid arthritis development?

Arthritis Res Ther 2019 Feb 14;21(1):56. Epub 2019 Feb 14.

Department of Rheumatology, Leiden University Medical Centre, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.

Background: MRI-detected subclinical joint inflammation in the hand joints of patients with undifferentiated arthritis (UA) predicts progression to rheumatoid arthritis (RA). It is unknown if adding MRI of the foot increases predictive accuracy compared to the hand alone.

Methods: 1. Read More

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http://dx.doi.org/10.1186/s13075-019-1845-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376768PMC
February 2019
1 Read

Do musculoskeletal ultrasound and magnetic resonance imaging identify synovitis and tenosynovitis at the same joints and tendons? A comparative study in early inflammatory arthritis and clinically suspect arthralgia.

Arthritis Res Ther 2019 Feb 14;21(1):59. Epub 2019 Feb 14.

Department of Rheumatology, Leiden University Medical Centre, Leiden, The Netherlands.

Objective: Ultrasound (US) and magnetic resonance imaging (MRI) are recommended in the diagnostic process of rheumatoid arthritis. Research on its comparability in early disease phases is scarce. Therefore, we compared synovitis and tenosynovitis detected by US and MRI on joint/tendon level. Read More

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http://dx.doi.org/10.1186/s13075-019-1824-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376767PMC
February 2019
2 Reads

Characteristics of late-onset spondyloarthritis in Japan: A retrospective cohort study.

Medicine (Baltimore) 2019 Feb;98(7):e14431

Department of Immunology and Rheumatology, Unit of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences.

Spondyloarthritis may be increasingly present in older patients as life expectancy increases. We investigated clinical differences between early-onset and late-onset spondyloarthritis in Japan.We retrospectively reviewed 114 patients consecutively diagnosed with spondyloarthritis. Read More

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http://dx.doi.org/10.1097/MD.0000000000014431DOI Listing
February 2019
2 Reads

Men and women's occupational activities and the risk of developing osteoarthritis of the knee, hip or hands: A systematic review and recommendations for future research.

Arthritis Care Res (Hoboken) 2019 Feb 14. Epub 2019 Feb 14.

Occupational Science & Occupational Therapy, University of British Columbia, Vancouver, B.C., Canada.

Objective: To systematically review the evidence for an increased risk of osteoarthritis in the hip, knee, hand, wrist, finger, ankle, foot, shoulder, neck and spine related to men and women's diverse occupational activities and to examine dose response information related to the frequency, intensity, and duration of work exposures and the risk of OA.

Methods: Established guidelines for systematic reviews in occupational health and safety studies were followed. MEDLINE, EMBASE, CINAHL and Cochrane Library were searched from inception to December 2017. Read More

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http://dx.doi.org/10.1002/acr.23855DOI Listing
February 2019
1 Read

Routine musculoskeletal ultrasound findings impact diagnostic decisions maximally in autoantibody-seronegative early arthritis patients.

Rheumatology (Oxford) 2019 Feb 8. Epub 2019 Feb 8.

Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.

Objective: The diagnostic value added by musculoskeletal ultrasound (MSUS) over standard clinical and laboratory parameters has proved difficult to quantify. The additive contribution to diagnostic classification of a pragmatic, 15 min MSUS protocol was appraised in a large, unselected cohort of early arthritis clinic attendees.

Methods: Detailed baseline characteristics were recorded. Read More

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http://dx.doi.org/10.1093/rheumatology/kez008DOI Listing
February 2019
1 Read

Usefulness of composite indices in the assessment of joint involvement in systemic lupus erythematosus patients: correlation with ultrasonographic score.

Lupus 2019 Mar 11;28(3):383-388. Epub 2019 Feb 11.

Lupus Clinic, Reumatologia, Dipartimento Medicina Interna e Specialità Mediche, Sapienza Università di Roma, Viale del Policlinico 155 - 00161 Rome, Italy.

Specific indices are not available to evaluate systemic lupus erythematosus (SLE) joint involvement; indeed, the application of indices validated for rheumatoid arthritis has been suggested. We evaluated the usefulness of organ specific composite indices, i.e. Read More

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http://dx.doi.org/10.1177/0961203319828527DOI Listing
March 2019
2 Reads

Peripheral and Central Sensitization of Pain in Individuals with Hand Osteoarthritis and Associations with Self-Reported Pain Severity.

Arthritis Rheumatol 2019 Feb 11. Epub 2019 Feb 11.

Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway.

Objectives: Pain sensitization, an important osteoarthritis (OA) pain mechanism, has not been substantially investigated in persons with hand OA. It is unknown how peripheral and central sensitization is related to self-reported hand pain.

Methods: Persons with verified hand OA in the Nor-Hand study underwent quantitative sensory testing of pressure pain Thresholds (PPT) locally (painful and non-painful finger joint) and remotely (wrist, trapezius and tibialis anterior muscle), and temporal summation (TS), a manifestation of central sensitization. Read More

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http://dx.doi.org/10.1002/art.40850DOI Listing
February 2019
2 Reads

Death of an Extensor Pollicis Longus due to a Funeral.

J Orthop Case Rep 2018 Sep-Oct;8(5):89-91

Department of Orthopaedics, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Introduction: Traumatic and atraumatic rupture of the extensor pollicis longus (EPL) tendon has been described as a result of mechanical or biological stresses. Common mechanisms include fractures of the distal radius, rheumatoid arthritis, local injection of steroids, and repetitive motion activities at the wrist.

Case Report: We report a case involving the spontaneous rupture of the EPL tendon in a relative of a deceased person who carried her coffin in a wrong way with no other predisposing factors. Read More

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http://dx.doi.org/10.13107/jocr.2250-0685.1228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367279PMC
February 2019
2 Reads

Shoulder and thorax kinematics contribute to increased power output of competitive handcyclists.

Scand J Med Sci Sports 2019 Feb 10. Epub 2019 Feb 10.

Peter Harrison Centre of Disability Sport, School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, UK.

Current knowledge of recumbent handbike configuration and handcycling technique is limited. The purpose of this study was to evaluate and compare the upper limb kinematics and handbike configurations of recreational and competitive recumbent handcyclists, during sport-specific intensities. Thirteen handcyclists were divided into two significantly different groups based on peak aerobic power output (PO ) and race experience; competitive (n = 7; 5 H3 and 2 H4 classes; PO : 247 ± 20 W) and recreational (n = 6; 4 H3 and 2 H4 classes; PO : 198 ± 21 W). Read More

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http://doi.wiley.com/10.1111/sms.13402
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http://dx.doi.org/10.1111/sms.13402DOI Listing
February 2019
6 Reads

Correlation between high-frequency ultrasonography of patients with early rheumatoid arthritis and anti-CCP antibody.

Medicine (Baltimore) 2019 Feb;98(6):e14083

Department of Ultrasound Medicine, Gansu Provincial People's Hospital, Lanzhou, Gansu Province, P. R. China.

Objectives: To study the correlation between high-frequency ultrasonography of patients with early rheumatoid arthritis (RA) and anti-cyclic citrullinated peptide (CCP) antibody.

Methods: Two wrists, 1st to 5th metacarpal phalangeal (MCP) and 1st to 5th proximal interphalangeal (PIP) joints of 53 early RA patients treated from October 2015 to October 2017 and 30 healthy subjects were examined by high-frequency ultrasonography. The thicknesses of synovial membrane, sheaths of 1st to 5th extensor tendons, flexor tendons and ulnar wrist extensor tendons were measured. Read More

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http://dx.doi.org/10.1097/MD.0000000000014083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380833PMC
February 2019
4 Reads

The Twist X-Ray: A Novel Test for Dynamic Scapholunate Instability.

J Wrist Surg 2019 Feb 3;8(1):61-65. Epub 2018 Oct 3.

Division of Hand Surgery, Department of Orthopaedic Surgery, Dandenong Hospital, Monash University, Melbourne, Australia.

 Scapholunate instability (SLI) is the most common form of carpal instability. Early detection of SLI is imperative as early reconstructive procedures can potentially prevent the natural history of progressive degenerative arthritis. After wrist arthroscopy, magnetic resonance imaging (MRI) remains the next best noninvasive diagnostic option; however, access still remains costly and is often limited in many health care systems worldwide. Read More

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http://dx.doi.org/10.1055/s-0038-1673344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358452PMC
February 2019
1 Read

Distal Radioulnar Joint Replacement in the Scarred Wrist.

J Wrist Surg 2019 Feb 19;8(1):55-60. Epub 2018 Sep 19.

Department of Orthopaedic Surgery, Hand and Upper Extremity Service, Massachusetts General Hospital, Harvard Medical School, Yawkey Center, Boston, Massachusetts.

 Radiocarpal or midcarpal arthritis can occur simultaneously with arthritis of the distal radioulnar joint (DRUJ), leading to functional impairment of the wrist. Treatment often involves wrist arthroplasty or arthrodesis, either with simultaneous or secondary procedures, addressing the DRUJ. Successful treatment of solitary DRUJ arthritis with DRUJ replacement has been reported. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1670681
Publisher Site
http://dx.doi.org/10.1055/s-0038-1670681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358447PMC
February 2019
10 Reads

Survival Rate on a 10-Year Follow-Up of Total Wrist Replacement Implants: A 23-Patient Case Series.

J Wrist Surg 2019 Feb 7;8(1):24-29. Epub 2018 Aug 7.

Department of Hand Surgery, SOS main, CCOM, University Hospital of Strasbourg, FMTS, University of Strasbourg, Illkirch, France.

 According to current literature, the estimated average survival rate for Remotion, the total wrist implants, is above 90% on an 8-year follow-up. We examined our series of Remotion to calculate its survival rate on a 10-year follow-up.  A total of 23 cases of total wrist implants were reviewed. Read More

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http://dx.doi.org/10.1055/s-0038-1668152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358454PMC
February 2019
2 Reads

Comparative Fracture Risks among US Medicaid Enrollees with and without Systemic Lupus Erythematosus.

Arthritis Rheumatol 2019 Feb 4. Epub 2019 Feb 4.

Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

Objective: Poor bone health is common in SLE patients. We evaluated fracture risks among low-income SLE and lupus nephritis patients compared to those without SLE.

Methods: We performed a cohort study within Medicaid 2007-2010, among SLE patients and age- and sex-matched non-SLE comparators. Read More

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http://dx.doi.org/10.1002/art.40818DOI Listing
February 2019
1 Read

The Role of Additional K-Wires on AO Type C Distal Radius Fracture Treatment with External Fixator in Young Population.

Adv Orthop 2019 1;2019:8273018. Epub 2019 Jan 1.

Department of Orthopedic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

Objectives: Several methods have been proposed to treat AO type C distal radius fracture. External fixator has gained popularity for its simple procedure and rapid recovery. Some surgeons suggested that additional K-wires may play a critical role in the outcome. Read More

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http://dx.doi.org/10.1155/2019/8273018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332986PMC
January 2019
1 Read

Validity of the rheumatoid arthritis MRI score applied to the forefeet using the OMERACT filter: a systematic literature review.

RMD Open 2018 5;4(2):e000796. Epub 2018 Dec 5.

Department of Rheumatology, Leiden University Medical Centre, Leiden, The Netherlands.

Objective: MRI depicts inflammation and structural damage in rheumatoid arthritis (RA). The validity of MRI-scoring of wrist-joints and metacarpophalangeal-joints according to the RA MRI score(RAMRIS) has been demonstrated. The Outcomes in Rheumatology Clinical Trials (OMERACT) RAMRIS Working Group recently called for validation of the RAMRIS of the metatarsophalangeal (MTP)-joints. Read More

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http://dx.doi.org/10.1136/rmdopen-2018-000796DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336094PMC
December 2018
1 Read

Juvenile case of multiple morphea profunda resulting in joint contracture that was successfully treated with cyclosporin A: A case report and review of the published works.

J Dermatol 2019 Jan 31. Epub 2019 Jan 31.

Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.

Morphea profunda refers to inflammatory and sclerotic lesions that start primarily from the deep dermis, subcutaneous fat and fascia. Its pediatric case published work is limited. Here, we report the case of an 8-year-old girl with a 5-year history of multiple subcutaneous nodules on her extremities and a right wrist joint contracture who had been previously diagnosed with juvenile idiopathic arthritis and treated with salazosulfapyridine, low-dose prednisolone (PSL) and methotrexate. Read More

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http://dx.doi.org/10.1111/1346-8138.14801DOI Listing
January 2019
1 Read

Validation of the Fitbit Charge 2 compared to the ActiGraph GT3X+ in older adults with knee osteoarthritis in free-living conditions.

PLoS One 2019 30;14(1):e0211231. Epub 2019 Jan 30.

Orthopaedic and Arthritis Center for Outcomes Research and Policy and Innovation eValuation in Orthopaedic Treatments (PIVOT) Center, Department of Orthopaedic Surgery, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.

Objective: To evaluate physical activity (PA) and sedentary time in subjects with knee osteoarthritis (OA) measured by the Fitbit Charge 2 (Fitbit) and a wrist-worn ActiGraph GT3X+ (AGW) compared to the hip-worn ActiGraph (AGH).

Design: We recruited a cohort of subjects with knee OA from rheumatology clinics. Subjects wore the AGH for four weeks, AGW for two weeks, and Fitbit for two weeks over a four-week study period. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0211231PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353569PMC
January 2019
13 Reads

"Carpal tunnel syndrome:" A bibliometric study of 35 years of research.

Authors:
Shri Ram

Neurol India 2019 Jan-Feb;67(Supplement):S55-S61

Central Library, Thapar Institute of Engineering and Technology, Patiala, Punjab, India.

Carpal tunnel syndrome (CTS) is a disease caused by compression of the median nerve passing through the wrist. Patients suffer from severe pain and paresthesis in the median nerve. Compression of the median nerve occurs, with prolonged working on keyboards (computer or laptop or music players) being one of the reasons along with others such as diabetes or rheumatoid arthritis. Read More

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http://dx.doi.org/10.4103/0028-3886.250698DOI Listing
January 2019
7 Reads

The Capitate-to-Axis-of-Radius Distance (CARD): A New Radiographic Measurement for Wrist and Carpal Alignment in the Sagittal Plane.

J Hand Surg Am 2019 Jan 23. Epub 2019 Jan 23.

Roth McFarlane Hand and Upper Limb Centre, St. Joseph's Hospital, London, Ontario, Canada.

Purpose: To determine the reliability of a new radiographic index evaluating sagittal radiocarpal alignment, the capitate-to-axis-of-radius distance (CARD). A secondary purpose was to validate this index by comparing values between normal wrists and those with distal radial fractures (DRFs) and rheumatoid arthritis (RA).

Methods: The CARD is defined as the perpendicular distance from the center of the capitate head to the axis of the radius. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03635023163082
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http://dx.doi.org/10.1016/j.jhsa.2018.10.024DOI Listing
January 2019
9 Reads

Reduction in Upper Limb Joint Surgery among Rheumatoid Arthritis Patients: An Interrupted Time Series Analysis using Danish Health Care Registers.

Arthritis Care Res (Hoboken) 2019 Jan 25. Epub 2019 Jan 25.

Center for Rheumatology and Spine Diseases, Rigshospitalet - Gentofte, Copenhagen, Denmark.

Objectives: Joint replacement surgery is a proxy of severe joint damage in rheumatoid arthritis (RA). The aim of this study was to assess the impact of the introduction of biological DMARDs (bDMARDs) on the incidence rate (IR) of upper limb joint replacements among newly diagnosed RA patients.

Methods: Using the Danish National Patient Register, incident RA patients from 1996-2012 were identified. Read More

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http://dx.doi.org/10.1002/acr.23835DOI Listing
January 2019
2 Reads

Association of hand grip strength with disease activity, disability and quality of life in children and adolescents with Juvenile Idiopathic Arthritis.

Adv Rheumatol 2018 Jun 28;58(1):11. Epub 2018 Jun 28.

Rheumatology and Rehabilitation Department, Faculty of Medicine, Assiut University, Assiut, Egypt.

Background: Juvenile idiopathic arthritis (JIA) affects wrist and hand joints leading to decrease hand function and patients' daily living activities. The assessment of hand grip strength (HGS) in children and adolescents with JIA is of major importance, and the association of HGS with JIA disease activity, disability and quality of life has not been explored. The primary objective of this study was to evaluate hand grip strength (HGS) in children and adolescents with Juvenile Idiopathic Arthritis (JIA) compared to matched healthy peers. Read More

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https://advancesinrheumatology.biomedcentral.com/articles/10
Publisher Site
http://dx.doi.org/10.1186/s42358-018-0012-1DOI Listing
June 2018
10 Reads

Outcomes after Scaphoid Excision and Midcarpal Arthrodesis for SNAC and SLAC Wrist Arthritis.

Ortop Traumatol Rehabil 2018 Oct;20(5):389-399

Klinika Chirurgii Ogólnej i Chirurgii Ręki, Pomorski Uniwersytet Medyczny w Szczecinie, Polska / Department of General and Hand Surgery, Pomeranian Medical University in Szczecin, Poland.

Background: Persistent, long-lasting pseudoarthrosis of the scaphoid or scapholunate dissociation results in arthrosis of the radio-scaphoid joint termed scaphoid non-union advanced collapse (SNAC) or scapholunate advanced collapse (SLAC), which causes pain, reduction in wrist movements and weakness of the hand grip. Scaphoid resection followed by "four-corner" midcarpal arthrodesis is a recognized treatment for this condition.

Material And Methods: The study evaluated the results of treatment of 27 patients with arthrosis of the wrist type SNAC (n = 15) and SLAC (n = 12) after an average of 4 years after surgery (range from 2 to 8 years) Results. Read More

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http://dx.doi.org/10.5604/01.3001.0012.8275DOI Listing
October 2018
1 Read

Benefits of wrist splinting in patients with rheumatoid arthritis.

Reumatologia 2018 23;56(6):362-367. Epub 2018 Dec 23.

Rheumatology Clinic and Outpatient Department, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland.

Objectives: The goal was to present the use of a functional wrist splint and its impact on hand function in patients with rheumatoid arthritis (RA).

Material And Methods: The study group comprised 104 women aged 18-65 and diagnosed with RA, who were treated in the Rheumatology Clinic and Outpatient Department of the National Institute of Geriatrics, Rheumatology and Rehabilitation in Warsaw. The control group consisted of 40 healthy women in the same age group. Read More

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https://www.termedia.pl/doi/10.5114/reum.2018.80713
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http://dx.doi.org/10.5114/reum.2018.80713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330686PMC
December 2018
11 Reads

Use of Magnetic Resonance Imaging to Support Dose Selection in a Phase II Trial of Baricitinib Combined with Conventional Synthetic Disease-modifying Antirheumatic Drugs in Rheumatoid Arthritis.

J Rheumatol 2019 Jan 15. Epub 2019 Jan 15.

From Spire Sciences, Inc. Boca Raton, FL, USA, The Leeds Institute of Rheumatic & Musculoskeletal Medicine, University of Leeds, Leeds, UK, Division of Immunology and Rheumatology, Stanford University, Stanford, CA, USA, Department of Rheumatology, University of Toronto, Toronto, ON, Canada, Botnar Research Centre, University of Oxford, Oxford, UK, Eli Lilly and Company, Indianapolis, IN, USA, Incyte Corporation, Wilmington, DE, USA Note: Dr. DiCarlo was an employee of Spires Science, Inc. at the time of this study; Dr. Luchi was an employee of Incyte Corporation at the time the study). This study was funded by Eli Lilly and Company and Incyte Corporation.

Objective: Magnetic resonance imaging (MRI) was used in a Phase IIb study (NCT01185353) of baricitinib in patients with RA to support dose selection for the Phase III program.

Methods: 301 patients with active RA on stable methotrexate were randomized 2:1:1:1:1 to placebo or once-daily baricitinib (1-, 2-, 4-, or 8-mg) for up to 24 weeks. 154 patients with definitive radiographic erosion had MRI of the hand/wrist at baseline and weeks 12 and 24. Read More

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http://dx.doi.org/10.3899/jrheum.171469DOI Listing
January 2019
2 Reads

Volar Approach to Percutaneous Fixation of Acute Nondisplaced Fractures of the Scaphoid.

Tech Hand Up Extrem Surg 2019 Mar;23(1):6-9

Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN.

Scaphoid fractures typically occur in young, healthy males at the peak of their employment and productivity, and left untreated or inadequately treated will ultimately progress to nonunion and a "predictable" pattern of wrist arthritis and carpal collapse. Nonoperative treatment of these fractures requires prolonged cast immobilization, which can lead to wrist stiffness, loss of grip strength, muscle atrophy, and protracted loss of economic productivity. To prevent these devastating sequelae, percutaneous techniques for scaphoid fixation have been described and popularized; however, these techniques are technically demanding as optimal position of the compression screw is required to achieve bony union. Read More

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http://dx.doi.org/10.1097/BTH.0000000000000213DOI Listing
March 2019
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Association of Angiogenic and Inflammatory Markers with Power Doppler Ultrasound Vascularity Grade and DAS28-CRP in Early Rheumatoid Arthritis: A Comparative Analysis.

Biomed Res Int 2018 25;2018:6906374. Epub 2018 Nov 25.

DNB (Medicine), FRCP, Professor and Head, Department of Rheumatology, Institute of Postgraduate Medical Education and Research, SSKM Hospital, Kolkata, India.

Objective: Upregulation of various proinflammatory and angiogenic mediators orchestrates the typical pathological synovial alterations in rheumatoid arthritis (RA). DAS28-CRP is commonly used for assessment of RA disease activity and power Doppler ultrasonography (PDUS) is an important modality for assessing synovial vascularity. This study was intended to look for the association of various inflammatory and angiogenic mediators, with respect to different PDUS vascularity grades and disease activity status, in early RA patients. Read More

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http://dx.doi.org/10.1155/2018/6906374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286781PMC
November 2018
2 Reads

The value of joint ultrasonography in predicting arthritis in seropositive patients with arthralgia: a prospective cohort study.

Arthritis Res Ther 2018 Dec 19;20(1):279. Epub 2018 Dec 19.

Amsterdam Rheumatology and immunology Center | Reade, Dr. Jan van Breemenstraat 2, 1056 AB, Amsterdam, The Netherlands.

Background: The value of joint ultrasonography (US) in the prediction of clinical arthritis in individuals at risk of developing rheumatoid arthritis (RA) is still a point of debate, due to varying scanning protocols and different populations. We investigated whether US abnormalities assessed with a standard joint protocol can predict development of arthritis in seropositive patients with arthralgia.

Methods: Anti-citrullinated protein antibodies and/or rheumatoid factor positive patients with arthralgia, but without clinical arthritis were included. Read More

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http://dx.doi.org/10.1186/s13075-018-1767-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300036PMC
December 2018
6 Reads

Functional Outcome after Treatment of Aggressive Tumours in the Distal Radius: Comparison between Reconstruction using Proximal Fibular Graft and Wrist Fusion.

Malays Orthop J 2018 Nov;12(3):19-23

Department of Orthopaedics, Hospital Universiti Sains Malaysia, Kubang Kerian, Malaysia.

Restoration of a functional hand is the ultimate goal following a distal radius tumour resection. The early outcomes of mobile wrist reconstruction are satisfactory; however, long-term results are unpredictable due to late wrist instability and degenerative arthritis. Our aim is to compare mobile wrist reconstruction with wrist fusion (pan-carpal fusion) in our cohort of patients. Read More

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http://dx.doi.org/10.5704/MOJ.1811.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287129PMC
November 2018
2 Reads

[A Case of Rheumatoid Arthritis Developed during Treatment with Nivolumab for Renal Cell Carcinoma].

Hinyokika Kiyo 2018 10;64(10):397-401

The Department of Urology, Nara Medical University.

A 66-year-old man underwent nephrectomy for right renal cell carcinoma (cT3bNOMl (PUL)). Thereafter, he was treated with sunitinib for lung metastasis as the first-line therapy for 5 months and then axitinib as the second-line therapy for 2 months. Because lung metastasis progressed despite molecular targeted therapies, nivolumab was used as the third-line treatment. Read More

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http://dx.doi.org/10.14989/ActaUrolJap_64_10_397DOI Listing
October 2018
3 Reads

Musculoskeletal ultrasound as a biomarker of remission - results from a one-year prospective study in patients with rheumatoid arthritis.

Med Ultrason 2018 Dec;20(4):453-460

Medical University of Plovdiv, Medical Faculty, Department of Propedeutic of Internal Diseases; University Hospital "Kaspela'', Rheumatology Clinic.

Aims: To assess the role of musculoskeletal ultrasound (MSUS) as a biomarker of remission and to compare the rates of clinical and imaging remission in patients with rheumatoid arthritis (RA) on different types of treatment.

Material And Methods: One hundred and forty-one patients underwent physical and ultrasound examination at 5 visits (at baseline and after 1, 3, 6 and 12 months). Patients were divided into two groups according to the type of treatment, which involved synthetic (sDMARDs) and biologic (bDMARDs) disease-modifying antirheumatic drugs. Read More

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http://dx.doi.org/10.11152/mu-1609DOI Listing
December 2018
3 Reads

Combined synovectomy and extensor carpi radialis longus transfer to realign and stabilise the rheumatoid wrist.

Orthop Traumatol Surg Res 2018 Nov 29. Epub 2018 Nov 29.

Faculté de médecine de Tours, service d'orthopédie traumatologie, université François-Rabelais de Tours, CHRU de Trousseau, 1C, avenue de la République, 37170 Chambray-les-Tours, France.

Background: In patients with rheumatoid arthritis, the surgical treatment of wrist lesions relies on synovectomy combined with stabilisation and realignment of the carpal bones. The objective of this study was to evaluate the outcomes and define the indications of extensor carpi radialis longus (ECRL) transfer to the extensor carpi ulnaris (ECU) as described by Clayton and Ferlic.

Hypothesis: ECRL-to-ECU transfer combined with synovectomy can prevent the development and/or progression of rheumatoid deformities at the wrist. Read More

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http://dx.doi.org/10.1016/j.otsr.2018.08.020DOI Listing
November 2018
2 Reads

The Advantages of Type III Scaphoid Nonunion Advanced Collapse (SNAC) Treatment With Partial Carpal Arthrodesis in the Dominant Hand: Results of 5-year Follow-up.

Med Arch 2018 Oct;72(4):253-256

Department of Orthopedics and Traumatology, Vito Fazzi Hospital, Lecce, Italy.

Introduction: The SNAC wrist (Scaphoid nonunion advanced collapse) is one of the complications following scaphoid fractures treated conservatively and one of the causes of wrist arthritis that the hand surgeon has to face most frequently. In these cases surgical management is usually warranted.

Materials And Methods: In the set time frame of 6 years we treated 15 SNAC wrist cases. Read More

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http://dx.doi.org/10.5455/medarh.2018.72.253-256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194931PMC
October 2018
3 Reads

My personal experience with arthroplasties in the hand and wrist over the past four decades.

J Hand Surg Eur Vol 2019 Feb 4;44(2):129-137. Epub 2018 Dec 4.

Capio/CFR Hospital, Hellerup, Denmark.

I summarize my changing views and practices of arthroplasty in hand surgery over the past four decades. I recommend simple resection of the trapeziectomy for advanced arthritis of the first carpometacarpal joint, silicone implants for the metacarpophalangeal joints and the proximal interphalangeal joints, and the total wrist arthroplasty for advanced wrist arthritis and collapse. I also outline technical tips of these procedures. Read More

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http://dx.doi.org/10.1177/1753193418817172DOI Listing
February 2019
3 Reads

Pseudogout: An Autoimmune Paraneoplastic Manifestation of Myelodysplastic Syndrome.

Cureus 2018 Sep 27;10(9):e3372. Epub 2018 Sep 27.

Internal Medicine, University at Buffalo / Sisters of Charity Hospital, Buffalo, USA.

Myelodysplastic syndrome (MDS) is often associated with autoimmune paraneoplastic manifestations. Seronegative arthritis is among one of them. Very rarely, pseudogout demonstrated as paraneoplastic autoimmune manifestations of MDS has been adumbrated so far. Read More

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http://dx.doi.org/10.7759/cureus.3372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260197PMC
September 2018
15 Reads

Sequence of joint tissue inflammation during rheumatoid arthritis development.

Arthritis Res Ther 2018 Nov 21;20(1):260. Epub 2018 Nov 21.

Department of Rheumatology C1-R, Leiden University Medical Centre, PO Box 9600, Leiden, 2300RC, the Netherlands.

Objective: Subclinical joint inflammation in patients with arthralgia is predictive for progression to rheumatoid arthritis (RA). However, the time course of progression for bone marrow edema (osteitis), synovitis, and/or tenosynovitis is unsettled. This longitudinal study assessed the course of magnetic resonance imaging (MRI)-detected subclinical joint inflammation during progression to RA. Read More

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https://arthritis-research.biomedcentral.com/articles/10.118
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http://dx.doi.org/10.1186/s13075-018-1756-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249752PMC
November 2018
13 Reads

Articular abnormalities that may mimic arthritis.

J Ultrason 2018 ;18(74):212-223

Leeds Teaching Hospitals and Leeds University, Leeds, UK.

There are numerous abnormalities that present with similar signs and symptoms to arthritis. In this article some of these conditions that can masquerade as arthritis are discussed. Synovial osteochondromatosis is an uncommon benign disorder marked by the metaplastic proliferation of multiple cartilaginous nodules in the synovial membrane of the joints, bursae, or tendon sheaths. Read More

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http://jultrason.pl/index.php/issues/volume-18-no-74/articul
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http://dx.doi.org/10.15557/JoU.2018.0032DOI Listing
January 2018
14 Reads

A Familial Case of Multicentric Carpotarsal Osteolysis Syndrome and Treatment Outcome.

J Pediatr Genet 2018 Dec 16;7(4):174-179. Epub 2018 Jun 16.

Department of Genetics, University of Alabama at Birmingham, Birmingham, Alabama, United States.

Multicentric carpotarsal osteolysis syndrome (MCTO) is a rare skeletal disorder caused by heterozygous mutations in the gene (v-maf musculoaponeurotic fibrosarcoma oncogene ortholog B). This is an autosomal dominant condition with a high frequency of sporadic cases. MCTO is characterized by osteolysis of the carpal, metacarpal, and tarsal bones beginning in early childhood with musculoskeletal rheumatologic symptoms such as pain and disability. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1657760
Publisher Site
http://dx.doi.org/10.1055/s-0038-1657760DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234043PMC
December 2018
15 Reads

Anatomic Pyrocarbon Hemiarthroplasty for Thumb Carpometacarpal Osteoarthritis in Patients under 65 Years: Mid Term Results.

J Hand Surg Asian Pac Vol 2018 Dec;23(4):469-473

† School of Medicine, Deakin University, Waurn Ponds, Geelong, Australia.

Background: To assess the midterm outcome of patients under 65 who underwent anatomic pyrocarbon hemiarthroplasty for thumb carpometacarpal (CMC) osteoarthritis.

Methods: A prospective analysis was performed of a consecutive series of active patients, less than 65 years of age, with symptomatic osteoarthritis who had undergone a CMC hemiarthroplasty using a stemmed metacarpal based, anatomic pyrolytic carbon resurfacing with an additional one third flexor carpi radialis (FCR) tendon transfer to maintain stability. The Wrightington Hand Score, Disability Arm Shoulder and Hand (DASH) Score, and the Patient Rated Wrist Evaluation Score (PRWE) were utilised. Read More

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http://dx.doi.org/10.1142/S2424835518500443DOI Listing
December 2018
18 Reads

Surgical Strategy for Scaphoid Nonunion Treatment.

J Hand Surg Asian Pac Vol 2018 Dec;23(4):450-462

1 Department of Orthopaedic Surgery, Dongguk University College of Medicine, Dongguk University Ilsan Hospital, Goyang, Korea.

Scaphoid fracture is the most common carpal fracture. Nonunion rate has been reported around 10 to 15% of scaphoid fractures. Risk factors for scaphoid nonunion are known as location, displacement, poor vascularity, time to treatment etc. Read More

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http://dx.doi.org/10.1142/S2424835518300049DOI Listing
December 2018
20 Reads