70,672 results match your criteria Wound Infection


Evidence for compromised data integrity in studies of liberal peri-operative inspired oxygen.

Anaesthesia 2019 Feb 17. Epub 2019 Feb 17.

Department of Anaesthesia and Pain Medicine, Royal Melbourne Hospital, Parkville, Vic., Australia.

In 2016 the World Health Organization recommended intra-operative ventilation with 80% inspired oxygen to reduce surgical site infection rates, based upon a meta-analysis of 15 randomised controlled trials, of which two were by Mario Schietroma's research group. Five trials by this group have been retracted for duplication, plagiarism, statistical error and lack of ethical approval. We analysed 40 papers by this group: 24 randomised controlled trials (5064 participants) and 16 observational studies (1847 patients). Read More

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http://dx.doi.org/10.1111/anae.14584DOI Listing
February 2019

Ankle fusion following failed initial treatment of complex ankle fractures in neuropathic diabetics.

Foot Ankle Surg 2019 Feb 5. Epub 2019 Feb 5.

The Department of Orthopaedic Surgery and Rehabilitation, Loyola University Health System, 2160 South First Avenue, Maywood, IL 60153, United States. Electronic address:

Background: Unstable ankle fractures in diabetics with peripheral neuropathy have an increased risk of postoperative complications, often leading to amputation. Primary ankle arthrodesis has been suggested as an alternative when acceptable reduction and mechanical stabilization cannot be obtained.

Methods: Over a fourteen year period, thirteen diabetic patients with peripheral neuropathy underwent an attempt at primary ankle arthrodesis following the early post-fracture development of acute neuropathic (Charcot) deformity of the ankle after sustaining a low energy unstable ankle fracture. Read More

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http://dx.doi.org/10.1016/j.fas.2019.01.010DOI Listing
February 2019

Adverse events and their risk factors 90 days after cervical spine surgery: analysis from the Michigan Spine Surgery Improvement Collaborative.

J Neurosurg Spine 2019 Feb 15:1-13. Epub 2019 Feb 15.

Departments of1Neurosurgery.

OBJECTIVEThe Michigan Spine Surgery Improvement Collaborative (MSSIC) is a statewide, multicenter quality improvement initiative. Using MSSIC data, the authors sought to identify 90-day adverse events and their associated risk factors (RFs) after cervical spine surgery.METHODSA total of 8236 cervical spine surgery cases were analyzed. Read More

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http://dx.doi.org/10.3171/2018.10.SPINE18666DOI Listing
February 2019

Efficacy of Pie-Crusting Technique on Soft Tissues in Distal Tibia and Fibula Fractures.

J Foot Ankle Surg 2019 Feb 13. Epub 2019 Feb 13.

Professor, Department of Orthopaedics and Traumatology, Faculty of Medicine, Mugla Sitki Kocman University, Mugla, Turkey.

Distal tibia and fibula fractures are challenging injuries to treat as evidenced by the high rates of wound complications because of vulnerable soft tissue coverage. The aim of this study was to examine the effect on soft tissue complications of the pie-crusting technique when applied between 2 incisions in distal tibia and fibula fractures treated with open reduction and internal fixation. We reviewed 34 patients with distal tibia and fibula fractures treated between September 2014 and March 2017. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10672516183043
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http://dx.doi.org/10.1053/j.jfas.2018.09.027DOI Listing
February 2019
5 Reads

A Macrophage-Pericyte Axis Directs Tissue Restoration via Amphiregulin-Induced Transforming Growth Factor Beta Activation.

Immunity 2019 Feb 6. Epub 2019 Feb 6.

Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FL, UK. Electronic address:

The epidermal growth factor receptor ligand Amphiregulin has a well-documented role in the restoration of tissue homeostasis after injury; however, the mechanism by which Amphiregulin contributes to wound repair remains unknown. Here we show that Amphiregulin functioned by releasing bioactive transforming growth factor beta (TGF-β) from latent complexes via integrin-α activation. Using acute injury models in two different tissues, we found that by inducing TGF-β activation on mesenchymal stromal cells (pericytes), Amphiregulin induced their differentiation into myofibroblasts, thereby selectively contributing to the restoration of vascular barrier function within injured tissue. Read More

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http://dx.doi.org/10.1016/j.immuni.2019.01.008DOI Listing
February 2019

Effectiveness of 80% vs 30-35% fraction of inspired oxygen in patients undergoing surgery: an updated systematic review and meta-analysis.

Br J Anaesth 2019 Mar 6;122(3):325-334. Epub 2019 Jan 6.

Department of Surgery, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Background: In 2016, the World Health Organization (WHO) strongly recommended the use of a high fraction of inspired oxygen (FiO) in adult patients undergoing general anaesthesia to reduce the risk of surgical site infection (SSI). Since then, further trials have been published, trials included previously have come under scrutiny, and one article was retracted. We updated the systematic review on which the recommendation was based. Read More

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http://dx.doi.org/10.1016/j.bja.2018.11.024DOI Listing

Safety of 80% vs 30-35% fraction of inspired oxygen in patients undergoing surgery: a systematic review and meta-analysis.

Br J Anaesth 2019 Mar 3;122(3):311-324. Epub 2019 Jan 3.

Norwich Medical School, University of East Anglia, Norwich, UK.

Background: Evidence-based guidelines from the World Health Organization (WHO) have recommended a high (80%) fraction of inspired oxygen (FiO) to reduce surgical site infection in adult surgical patients undergoing general anaesthesia with tracheal intubation. However, there is ongoing debate over the safety of high FiO. We performed a systematic review to define the relative risk of clinically relevant adverse events (AE) associated with high FiO. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00070912183135
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http://dx.doi.org/10.1016/j.bja.2018.11.026DOI Listing
March 2019
3 Reads

Airway macrophages as the guardians of tissue repair in the lung.

Immunol Cell Biol 2019 Feb 15. Epub 2019 Feb 15.

Inflammation, Repair & Development, National Heart & Lung Institute, Imperial College London, London, UK.

The lungs present a challenging immunological dilemma for the host. Anatomically positioned at the environmental interface, they are constantly exposed to antigens, pollutants and microbes, while simultaneously facilitating vital gas exchange. Remarkably, the lungs maintain a functionally healthy state, ignoring harmless inhaled proteins, adapting to toxic environmental insults and limiting immune responses to allergens and pathogenic microbes. Read More

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http://dx.doi.org/10.1111/imcb.12235DOI Listing
February 2019

Short-term Results After Totally Robotic Restorative Total Proctocolectomy With Ileal Pouch Anal Anastomosis for Ulcerative Colitis.

Surg Laparosc Endosc Percutan Tech 2019 Feb 12. Epub 2019 Feb 12.

Department of General Surgery, School of Medicine, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.

In this study, we aimed to present our initial experience on totally robotic total restorative proctocolectomy in ulcerative colitis (UC) patients. Patients undergoing a totally robotic restorative total proctocolectomy with ileal J-pouch anal anastomosis for UC between January 2015 and November 2017 were included. The da Vinci Xi was used for the operations. Read More

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http://dx.doi.org/10.1097/SLE.0000000000000645DOI Listing
February 2019

Bacteria-activated chlorin e6 ionic liquid based on cation and anion dual-mode antibacterial action for enhanced photodynamic efficacy.

Biomater Sci 2019 Feb 15. Epub 2019 Feb 15.

Department of pharmacy, The Fourth Military Medical University, Changlexilu 169, Xi'an city, China.

With the increase in antibiotic resistance, the development of new antibacterial agents is urgent. Photosensitizers with no detectable resistance are promising antibacterial agents. However, most photosensitizers are insoluble, structurally unstable and ineffective against Gram-negative bacteria due to their negatively charged cell wall that hinder their use. Read More

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http://dx.doi.org/10.1039/c8bm00990bDOI Listing
February 2019
1 Read

Treatment of diabetic foot wounds with acellular fish skin graft rich in omega-3: a prospective evaluation.

J Wound Care 2019 Feb;28(2):76-80

Consultant Vascular Surgeon; Department of Vascular Surgery, Royal Cornwall Hospital, UK.

Objective:: To evaluate the potential benefit of an intact fish skin graft rich in omega-3 (Kerecis Omega3), in the management of postoperative diabetic foot wounds.

Method:: Prospective evaluation in eight patients with diabetes following forefoot surgery. The dressing was applied weekly for a period of six weeks in the diabetic foot clinic. Read More

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http://dx.doi.org/10.12968/jowc.2019.28.2.76DOI Listing
February 2019

Pilot study to assess the use of a fluorescence imaging system for assessment of amputation healing.

J Wound Care 2019 Feb;28(Sup2):S24-S29

Michigan State University College of Human Medicine, Grand Rapids, Michigan, US.

Objective:: The purpose of this study was to use a fluorescence imaging system (FIS) (SPYElite, NOVADAQ, US) during lower extremity amputations and develop parameters to predict amputation healing, for which there are no proven, objective tests. We hypothesised that the FIS may identify areas of poor perfusion at the time of amputation and predict potential healing complications. There are no studies involving the FIS used in this study in lower extremity amputation. Read More

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http://dx.doi.org/10.12968/jowc.2019.28.Sup2.S24DOI Listing
February 2019

The role of collagenase ointment in acute burns: a systematic review and meta-analysis.

J Wound Care 2019 Feb;28(Sup2):S9-S15

Assistant Professor; Keck School of Medicine, University of Southern California, Los Angeles, US. Division of Plastic Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, US.

Objective:: A systematic review and meta-analysis was performed to summarise the state of the literature in regard to the efficacy and uses of clostridial collagenase ointment (CCO) in the burn patient.

Method:: A systematic review of articles available on PubMed, Scopus and OvidSP Medline was performed. Keywords used in the search process included burns, thermal injury, collagenase, enzymatic debridement, wound care. Read More

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http://dx.doi.org/10.12968/jowc.2019.28.Sup2.S9DOI Listing
February 2019

Skin integrity and infection prevention: ideas to action.

Authors:
Rachel Webb

J Wound Care 2019 Feb;28(Sup2):S3

Editor Journal of Wound Care.

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http://dx.doi.org/10.12968/jowc.2019.28.Sup2.S3DOI Listing
February 2019

Pentraxin-3: A new parameter in predicting the severity of diabetic foot infection?

Int Wound J 2019 Feb 15. Epub 2019 Feb 15.

Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Firat University, Elazig, Turkey.

This study was undertaken to evaluate the diagnostic and prognostic values of pentraxin-3 (PTX-3) in patients with infected diabetic foot ulcers (IDFU) as well as to assess the association between PTX-3 levels and IDFU severity. This study included 60 IDFU patients (Group 1), 45 diabetic patients without DFU (Group 2), and 45 healthy controls. Patients with IDFU were divided into mild, moderate, and severe subgroups based on classification of clinical severity. Read More

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http://dx.doi.org/10.1111/iwj.13075DOI Listing
February 2019

Electroceutical Treatment of Pseudomonas aeruginosa Biofilms.

Sci Rep 2019 Feb 14;9(1):2008. Epub 2019 Feb 14.

Department of Microbial Infection and Immunity, The Ohio State University, Columbus, Ohio, 43210, USA.

Electroceutical wound dressings, especially those involving current flow with silver based electrodes, show promise for treating biofilm infections. However, their mechanism of action is poorly understood. We have developed an in vitro agar based model using a bioluminescent strain of Pseudomonas aeruginosa to measure loss of activity and killing when direct current was applied. Read More

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http://dx.doi.org/10.1038/s41598-018-37891-yDOI Listing
February 2019
2 Reads

Evidence of sustained reductions in the relative risk of acute hepatitis B and C virus infections, and the increasing burden of hepatitis a virus infection in Egypt: comparison of sentinel acute viral hepatitis surveillance results, 2001-17.

BMC Infect Dis 2019 Feb 14;19(1):159. Epub 2019 Feb 14.

Ministry of Health and Population, Cairo, Egypt.

Background: Egypt ranks fifth for the burden of viral hepatitis worldwide. As part of Egypt's renewed national strategy for the elimination of viral hepatitis, surveillance for acute viral hepatitis (AVH) was re-established during 2014-2017 to describe the current epidemiology and associated risk factors, and changes from surveillance conducted during 2001-2004.

Methods: Patients with suspected AVH were enrolled, completed a questionnaire, and provided blood for testing for hepatitis viruses A (HAV), B (HBV), C (HCV), D, and E (HEV) infections by enzyme-linked immunosorbent assay. Read More

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http://dx.doi.org/10.1186/s12879-019-3806-9DOI Listing
February 2019

Carbapenem-resistant Acinetobacter baumannii isolates carrying the blaOXA genes with an upstream ISAba1: The first report of a novel OXA subclass from Iran.

J Glob Antimicrob Resist 2019 Feb 11. Epub 2019 Feb 11.

Infectious Diseases Research Center, Golestan University of Medical Sciences, Gorgan, Iran; Department of Microbiology, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran. Electronic address:

Objectives: Carbapenem-resistant Acinetobacter baumannii (CRAB) has emerged as a serious challenge and poses a threat to public health worldwide. This study aimed to determine drug susceptibility of A. baumannii, and then, investigate oxacillinase-encoding determinants and their association with ISAba1 sequence in CRAB isolates. Read More

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http://dx.doi.org/10.1016/j.jgar.2018.12.011DOI Listing
February 2019

Neurosurgical and Scalp Reconstructive Challenges During Craniotomy in the Setting of Cutis Verticis Gyrata.

World Neurosurg 2019 Feb 11. Epub 2019 Feb 11.

Department of Neurosurgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA. Electronic address:

Cutis verticis gyrata (CVG) is a rare condition of the scalp in which thickening of the dermis induces rigid folds and furrows resembling the cerebral cortex. Two forms of primary CVG exist, essential in which CVG is the only presenting problem and non-essential in which the scalp condition occurs along with neuropsychiatric ailments. CVG can also occur secondary to a variety of causes including inflammatory, neoplastic, and metabolic conditions or drug use. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.217DOI Listing
February 2019

Laparoscopic versus lichtenstein hernioplasty for inguinal hernias: a systematic review and Meta-analysis of randomized controlled trials.

Minim Invasive Ther Allied Technol 2019 Feb 14:1-8. Epub 2019 Feb 14.

a Department of Hernia and Abdominal Wall Surgery, Beijing Chaoyang Hospital , Capital Medical University , Beijing , China.

Background: This meta-analysis aimed to explore the safety and efficacy of Lichtenstein versus laparoscopic hernioplasty for inguinal hernias based on eligible randomized controlled trials (RCTs).

Material And Methods: We searched several electronic databases to identify eligible studies based on the index words updated to March 2018.We also searched related publication sources and only included eligible RCTs in the current analysis. Read More

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https://www.tandfonline.com/doi/full/10.1080/13645706.2019.1
Publisher Site
http://dx.doi.org/10.1080/13645706.2019.1569534DOI Listing
February 2019
1 Read

A neglected causative agent in diabetic foot infection: a retrospective evaluation of 13 patients with fungal etiology

Turk J Med Sci 2019 Feb 11;49(1):81-86. Epub 2019 Feb 11.

Background/aim: Clinicians often neglect fungal infections and do not routinely investigate deep tissue from the wound for fungal culture and sensitivity due to insufficient information in the literature. In this study, we aimed to evaluate fungal etiology of invasive fungal diabetic foot which is rarely reported in the literature.

Materials And Methods: The patients who were unresponsive to antibiotic therapy and those with positive fungal in bone or deep tissue culture were enrolled in the study. Read More

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http://dx.doi.org/10.3906/sag-1809-74DOI Listing
February 2019

Does lymphadenectomy effect postoperative surgical morbidity and survival in patients with adult granulosa cell tumor of ovary?

J Obstet Gynaecol Res 2019 Feb 13. Epub 2019 Feb 13.

Division of Gynecologic Oncology, University of Medical Sciences Tepecik Education and Research Hospital, Izmir, Turkey.

Aim: To evaluate the effect of lymphadenectomy on surgical morbidity and survival in adult granulosa cell tumor (AGCT) of the ovary.

Methods: Patients who underwent surgical treatment for AGCT between January 1993 and January 2016 were identified. Data were collected for patient age, menopausal status, surgical staging, lymphadenectomy, postoperative complications (anemia, wound infection, incisional hernia), length of hospital stay, follow-up duration, site and time for recurrence, management of recurrence and vital status. Read More

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http://dx.doi.org/10.1111/jog.13928DOI Listing
February 2019

Management of vulvar lymphedema of filarial origin in a pregnant woman and its outcome: A case report.

J Obstet Gynaecol Res 2019 Feb 13. Epub 2019 Feb 13.

Department of Obstetrics and Gynaecology, Jawaharlal Nehru Institute of Post Graduate Education and Research, Pondicherry, India.

Lymphedema of filarial origin affecting the vulva is extremely rare. It is a dilemma if seen in a pregnant woman as there are no guidelines regarding excision and the mode of delivery. With the World Health Organization-driven global program to eradicate filaria, it is unfortunate to see such cases. Read More

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http://dx.doi.org/10.1111/jog.13933DOI Listing
February 2019

Avoidance of general anesthesia for circumcision in infants under 6 months of age using a modified Plastibell technique.

Pediatr Surg Int 2019 Feb 14. Epub 2019 Feb 14.

Department of Surgery, New York Presbyterian Brooklyn Methodist Hospital, 506 6th street, Brooklyn, NY, 11215, USA.

Purpose: There is currently no gold standard for the type of analgesia or preferred circumcision technique in infants requiring circumcision after 1 month of age. Our study presents a modified Plastibell circumcision technique, which offers excellent surgical outcomes, and can be performed under local anesthesia until 6 months of age, thereby avoiding the risks of general anesthesia in delayed circumcision.

Methods: This is a retrospective case series of 508 consecutive male infants between 1 and 6 months of age, from one institution, who all underwent circumcision under local anesthesia, performed by the same pediatric surgeon, from 2013 to 2018. Read More

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http://dx.doi.org/10.1007/s00383-019-04452-xDOI Listing
February 2019

Intestinal Microbiota as a Host Defense Mechanism to Infectious Threats.

Front Microbiol 2018 23;9:3328. Epub 2019 Jan 23.

Department of Infectious Diseases, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.

The intestinal microbiota is a complex microbial community, with diverse and stable populations hosted by the gastrointestinal tract since birth. This ecosystem holds multiple anti-infectious, anti-inflammatory, and immune modulating roles decisive for intestinal homeostasis. Among these, colonization resistance refers to the dynamic antagonistic interactions between commensals and pathogenic flora. Read More

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http://dx.doi.org/10.3389/fmicb.2018.03328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362409PMC
January 2019

Drainage No Drainage after Laparoscopic Cholecystectomy for Acute Cholecystitis: A Meta-Analysis.

Am Surg 2019 Jan;85(1):86-91

To conduct a randomized controlled trial (RCT), meta-analysis to assess the effectiveness of drains in reducing complications after laparoscopic cholecystectomy (LC) for acute cholecystitis needs to be carried out. An electronic search of PubMed, Embase, Science Citation Index, and the Cochrane Library from January 1990 to January 2018 was performed to identify randomized clinical trials that compare prophylactic drainage with no drainage in LC for acute cholecystitis. The outcomes were calculated as odds ratios (ORs) with 95 per cent confidence intervals (CIs) using RevMan 5. Read More

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January 2019

Anal Sphincteroplasty in the Minimally Invasive Era: Assessment of National Trends and Complications.

Am Surg 2019 Jan;85(1):46-51

Fecal incontinence is a debilitating and underreported condition. Despite introduction of novel therapies in recent years, anal sphincteroplasty (AS) remains the surgical choice for certain patients. Previous reports have primarily focused on single-surgeon or single-center experience with AS. Read More

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January 2019

Robotic Surgery Is More Expensive with Similar Outcomes in Sleeve Gastrectomy: Analysis of the NIS Database.

Am Surg 2019 Jan;85(1):39-45

The aim of this study was to compare postoperative outcomes after robotic-assisted and laparoscopic bariatric sleeve gastrectomy (SG). Sleeve gastrectomy is traditionally performed using laparoscopic techniques. Robotic-assisted surgery enables surgeons to perform minimally invasive SG, but with unknown benefits. Read More

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January 2019

Effect of Negative Pressure Wound Therapy on Wound Complications Post-Pancreatectomy.

Am Surg 2019 Jan;85(1):1-7

Surgical site infection (SSI) and incisional hernia are common complications after major pancreatectomy. We investigated the effects of negative pressure wound therapy (NPWT) on short- and long-term wound outcomes in patients undergoing pancreatectomy. A randomized controlled trial comparing the effect of NPWT with standard surgical dressing (SSD) on wounds was performed in 265 patients undergoing open gastrointestinal resections from 2012 to 2016. Read More

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January 2019

Characterization of the clonal profile of methicillin resistant Staphylococcus aureus isolated from patients with early post-operative orthopedic implant based infections.

Ann Clin Microbiol Antimicrob 2019 Feb 13;18(1). Epub 2019 Feb 13.

Division of Bacteriology, National Institute of Cholera and Enteric Diseases, Kolkata, India.

Background: To analyze the molecular epidemiology and to compare between the major methicillin resistant Staphylococcus aureus biotypes for association with patient characteristics who had an implant for closed fracture and developed early post-operative wound infections (POWI) in a tertiary care hospital of India.

Methods: Pulsed-field gel electrophoresis (PFGE), antimicrobial resistance, accessory gene regulator (agr) and staphylococcal cassette chromosome mec (SCCmec) types, Paton-Valentine leukocidin (PVL) gene, toxin gene profiling, biofilm formation and patient demographics were correlated with MLST clonal complexes (CC).

Findings: Overall eight different sequence types (STs) were detected with a predominance of ST239 (66%), ST22 (18%) and some minor types ST772, ST30 (4% each) ST1, ST642, ST6, ST107 (2% each). Read More

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http://dx.doi.org/10.1186/s12941-019-0307-zDOI Listing
February 2019

Non-Uremic Calciphylaxis: A Rare Diagnosis with Limited Therapeutic Strategies.

Eur J Case Rep Intern Med 2018 27;5(12):000986. Epub 2018 Dec 27.

Unidade Funcional de Medicina 2.1, Hospital de Santo António dos Capuchos, Centro Hospitalar de Lisboa Central, Lisbon, Portugal.

Calciphylaxis is a rare condition characterized by the emergence of non-healing skin ulcers secondary to arterial calcification and thrombosis, typically diagnosed in patients with end-stage kidney disease (ESKD). When it develops in patients without ESKD, it is called non-uremic calciphylaxis (NUC). The latter is an even rarer diagnosis with an uncertain pathophysiology and a high mortality rate (52%), mainly due to sepsis (50%). Read More

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http://dx.doi.org/10.12890/2018_000986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346971PMC
December 2018

Determination of Tobramycin and Vancomycin Exposure Required to Eradicate Biofilms on Muscle and Bone Tissue .

J Bone Jt Infect 2019 1;4(1):1-9. Epub 2019 Jan 1.

School of Biological & Health Systems Engineering, Arizona State University, Tempe, AZ, USA.

: Bacterial biofilms cause chronic orthopaedic infections. Surgical debridement to remove biofilm can be ineffective without adjuvant local antimicrobials because undetected biofilm fragments may remain in the wound and reestablish the infection if untreated. However, the concentrations and duration of antimicrobial exposure necessary to eradicate bacteria from clinical biofilms remain largely undefined. Read More

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http://dx.doi.org/10.7150/jbji.29711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367195PMC
January 2019
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Do It Better: Cross Mattress for Chest Drain Insertion Site Security Offers Quality Outcome in Chest Trauma Patients Required Tube Thoracostomy.

Mymensingh Med J 2019 Jan;28(1):200-205

Dr Md Faizus Sazzad, Associate Consultant, Department of Cardiac Surgery, Ibrahim Cardiac Hospital & Research Institute, Dhaka, Bangladesh.

We examined the hypothesis that the cross mattress for chest drain insertion site security is better than that of polypropylene horizontal mattress in chest trauma patient required tube thoracostomy at the Department of Casualty Surgery, Dhaka Medical College Hospital, Dhaka, Bangladesh from January 2016 to June 2016. Accordingly we prospectively studied 50 consecutive patients who needed chest tube insertion. In 25 consecutive cases chest drain insertion site was secured with polypropylene horizontal mattress technique (Control- Group A) and another 25 consecutive patients had a cross-mattress with non-absorbable suture materials (Experimental- Group B). Read More

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January 2019

Outcome of Single Stage Correction of High Variety of Anorectal Malformation.

Mymensingh Med J 2019 Jan;28(1):8-14

Dr Sangul Islam, Medical Officer, SOPD, Mymensingh Medical College Hospital (MMCH), Mymensingh, Bangladesh.

The standard treatment of high variety anorectal malformation (ARM) is the staged approach. A growing interest in one stage correction of high variety ARM was noted recently. The aim of this study was to examine the feasibility, safety and outcome of single stage correction of High variety ARM. Read More

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January 2019

Sex-Related Differences in Patients Undergoing Thoracic Aortic Surgery: Evidence from the Canadian Thoracic Aortic Collaborative.

Circulation 2019 Feb 13. Epub 2019 Feb 13.

Surgery, London Health Sciences Center, Canada.

Background: Contemporary outcomes following surgical management of thoracic aortic disease have improved; however, the impact of sex-related differences is poorly understood.

Methods: A total of 1653 patients (498 (30.1%) female) underwent thoracic aortic surgery with hypothermic circulatory arrest between 2002 and 2017 in ten institutions of the Canadian Thoracic Aortic Collaborative. Read More

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.035805DOI Listing
February 2019
1 Read

A case of persistent fever, cutaneous manifestations and pulmonary and splenic nodules: clinical experience and a literature review.

Intern Med J 2019 Feb;49(2):247-251

Department of Respiratory, Peking University Shenzhen Hospital, Shenzhen, Gangdong, China.

Pyoderma gangrenosum (PG) is a rare and recurrent ulcerating, non-infectious, inflammatory dermatosis, with occasional concomitant extracutaneous manifestations. The pathogenesis and aetiology of PG are unknown. Moreover, early diagnosis is challenging because there are several visceral manifestations that may occur prior to the skin findings, such that misdiagnosis of PG as an infection is common. Read More

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http://dx.doi.org/10.1111/imj.14201DOI Listing
February 2019
1 Read

Postoperative Infection in Cementless and Cemented Total Knee Arthroplasty: A Propensity Score Matched Analysis.

J Knee Surg 2019 Feb 12. Epub 2019 Feb 12.

Department of Orthopaedic Surgery, Cleveland Clinic Foundation, Cleveland, Ohio.

The ongoing debate on fixation in total knee arthroplasty (TKA) has become increasingly relevant with its increased use in a younger patient population and the advent of novel cementless prostheses. Recent literature suggests modern cementless implants are comparable to their cemented counterparts in terms of survivorship and functional outcomes. What has not been well-assessed is whether the two modalities differ with respect to infection rates which was the purpose of this study. Read More

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http://dx.doi.org/10.1055/s-0039-1678678DOI Listing
February 2019
1 Read

[Imaging of bacteria in burn wounds treated with split-thicknessgrafts in MEEK/MESH technique: a pilot study with first experiences in clinical wound evaluation with autofluorescence].

Handchir Mikrochir Plast Chir 2019 Feb 12. Epub 2019 Feb 12.

Medizinische Hochschule Hannover, Klinik für Plastische, Ästhetische, Hand- und Wiederherstellungschirurgie, Replantationszentrum Niedersachsen, Schwerbrandverletztenzentrum Niedersachsen.

Background: Partial and full thickness burns require surgical treatment, such as early débridement and skin transplantation in MEEK/MESH technique or further reconstructive surgery. Infections of burns or transplanted areas limit surgical success and increase patient mortality. For split-thickness grafts in MEEK technique a superficial silk is applied as a protective on-top dressing, whereas in MESH technique fatty gauze and foam are used as standard protective covers over five to seven days. Read More

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http://dx.doi.org/10.1055/a-0584-7488DOI Listing
February 2019
1 Read

Occurrence and characterization of Escherichia coli ST410 co-harbouring blaNDM-5, blaCMY-42 and blaTEM-190 in a dog from the UK.

J Antimicrob Chemother 2019 Feb 6. Epub 2019 Feb 6.

Institute of Veterinary Science, University of Liverpool, Leahurst Campus, Cheshire, UK.

Background/objectives: Carbapenemase-producing Enterobacteriaceae (CPE) are a public health threat, and have been found in humans, animals and the environment. Carbapenems are not authorized for use in EU or UK companion animals, and the prevalence of carbapenem-resistant Gram-negative bacilli (CRGNB) in this population is unknown.

Methods: We investigated CRGNB isolated from animal specimens received by one diagnostic laboratory from 34 UK veterinary practices (September 2015-December 2016). Read More

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http://dx.doi.org/10.1093/jac/dkz017DOI Listing
February 2019
1 Read

Reversal of Diverting Loop Ileostomy Using Hand-Sewn Side-to-Side End-to-End Anastomosis after Low Anterior Resection for Rectal Cancer: A Single Center Experience.

Am Surg 2018 Nov;84(11):1741-1744

Construction of diverting loop ileostomy has become a common adjunct to low anterior resection for rectal cancer because it substantially reduces the severity of postoperative morbidity. Various trials have compared hand-sewn with stapled anastomotic techniques, but the existing evidence regarding different configurations of hand-sewn anastomoses is scarce. The aim of this study is to compare the early postoperative outcomes of loop ileostomy reversal using the hand-sewn end-to-end or side-to-side configuration. Read More

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November 2018
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Comparative Study of Nipple-Areola Complex Position and Patient Satisfaction After Unilateral Mastectomy and Immediate Expander-Implant Reconstruction Nipple-Sparing Mastectomy Versus Skin-Sparing Mastectomy.

Aesthetic Plast Surg 2019 Feb 11. Epub 2019 Feb 11.

Department of Plastic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, South Korea.

Background: Major surgical concerns associated with nipple-sparing mastectomy (NSM) are partial or total nipple-areola complex (NAC) loss, decreased sensation, and nipple malposition. Patient satisfaction and NAC outcomes including malposition in patients who have undergone unilateral expander-implant reconstruction after NSM as compared with skin-sparing mastectomy (SSM) remain unclear. Therefore, the aim of this study was to assess patient satisfaction and NAC outcomes of breast cancer patients who underwent spared or reconstructed NAC after unilateral NSM as compared with unilateral SSM. Read More

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http://dx.doi.org/10.1007/s00266-018-1217-8DOI Listing
February 2019
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Preoperative Malnutrition Negatively Correlates With Postoperative Wound Complications and Infection After Total Joint Arthroplasty: A Systematic Review and Meta-Analysis.

J Arthroplasty 2019 Jan 9. Epub 2019 Jan 9.

Complex Joint Reconstruction Center, Hospital for Special Surgery, New York, NY.

Background: Malnutrition continues to be prevalent in the general population. A variety of studies have correlated poor nutritional status with reduced perioperative outcomes. However, the correlation between serologic malnutrition and arthroplasty outcomes has not been systematically evaluated. Read More

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http://dx.doi.org/10.1016/j.arth.2019.01.005DOI Listing
January 2019
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Synthesis of photo-excited Chlorin e6 conjugated silica nanoparticles for enhanced anti-bacterial efficiency to overcome methicillin-resistant Staphylococcus aureus.

Chem Commun (Camb) 2019 Feb 11. Epub 2019 Feb 11.

Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics (SIIA), Chengdu University, Chengdu, 610052, Sichuan, P. R. China. and Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.

Multidrug resistant bacterial infection remains a significant public concern. In this report, photosensitizer Chlorin e6 doped silica was synthesized. This hybrid structure exhibits enhanced photostability and high antibacterial efficiency towards Staphylococcus aureus (S. Read More

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http://xlink.rsc.org/?DOI=C9CC00166B
Publisher Site
http://dx.doi.org/10.1039/c9cc00166bDOI Listing
February 2019
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Fasciitis and Streptococcal Toxic-shock Syndrome: The Importance of Early Diagnosis and Surgical Management.

J Orthop Case Rep 2018 Sep-Oct;8(5):57-60

Department of Orthopedics and Trauma, Carlos E. Ottolenghi, Hospital Italiano de Buenos Aires, Juan D. PeronStreet 4190, C1181ACH, Ciudad Autónoma de Buenos Aires, Argentina.

Introduction: Fasciitis of the limb and toxic-shock syndrome due to Streptococcus Pyogenes infection is considered a surgical emergency. This condition may occur in previously healthy patients. It is a life-threatening condition with high morbidity rates when treatment is delayed due to poor diagnosis and non-surgical intervention. Read More

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http://dx.doi.org/10.13107/jocr.2250-0685.1212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367280PMC
February 2019
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Postoperative Spine Infection - Postoperative MRSA Infection in a Wrongly Diagnosed Case of Spine Trauma.

Authors:
Suresh Pillai

J Orthop Case Rep 2018 Sep-Oct;8(5):54-56

Department of Spine, Aster MIMS Hospital, Govindapurasam, Calicut, Kerala, India.

Introduction: Pathological fractures resulting from trivial trauma may be overlooked, especially, when it is after a road traffic accident.

Case Report: A 56-year-old male was operated elsewhere for burst fracture L3 vertebra following a trivial road traffic accident. Due to the persistence of symptoms, he was reevaluated. Read More

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http://dx.doi.org/10.13107/jocr.2250-0685.1210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367292PMC
February 2019

Antibiotic Susceptibility Pattern of Bacterial Pathogens Isolated from Infected Lesions.

J Nepal Health Res Counc 2019 Jan 28;16(41):446-451. Epub 2019 Jan 28.

Department of Pathology, Kathmandu Medical College, Kathmandu, Nepal.

Background: Wound infection with multidrug resistant bacteria along with risk factors is a major burden and challenge to the health care persons. This study focuses on antibiotic susceptibility pattern of bacterial isolates and risk factors of patients with infected wounds.

Methods: This was a cross-sectional study conducted between November 2017 to June 2018 in Kathmandu University Hospital. Read More

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January 2019
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[Application of self-made chronic wound closure device in the repair of scarred lower extremity wounds].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2019 Feb;33(2):219-222

Department of orthopedics, the Joint Service Support Force 920 th Hospital of Chinese PLA, Kunming Yunnan, 650032, P.R.China.

Objective: To investigate the effectiveness of self-made limb chronic wound closure device in the treatment of scarred lower limbs and complex skin and soft tissue defects.

Methods: Between January 2014 and January 2017, 29 patients with complex fractures of the lower extremities and skin and soft tissue defects were treated. There were 19 males and 10 females with an average age of 31. Read More

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http://dx.doi.org/10.7507/1002-1892.201803045DOI Listing
February 2019
2 Reads

[Application of high frequency color Doppler ultrasound combined with wide-field imaging in the preoperative navigation of anterolateral thigh perforator flap surgery].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2019 Feb;33(2):190-194

Department of Burn and Plastic Surgery, Affiliated Hospital of Zunyi Medical College, Zunyi Guizhou, 563000, P.R.China.

Objective: To investigate the application of high frequency color Doppler ultrasound (HFCDU) combined with wide-field imaging in the preoperative navigation of anterolateral thigh perforator flap graft.

Methods: Between January 2017 and March 2018, 28 patients with skin and soft tissue defects were treated, including 22 males and 6 females, with an average age of 33.5 years (range, 17-66 years). Read More

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http://dx.doi.org/10.7507/1002-1892.201810025DOI Listing
February 2019
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A systematic review and meta-analysis of functional outcomes and complications following external fixation or open reduction internal fixation for distal intra-articular tibial fractures: an update.

Eur J Orthop Surg Traumatol 2019 Feb 9. Epub 2019 Feb 9.

Department of Orthopaedic Surgery and Traumatology, Odense University Hospital, Odense, Denmark.

Purpose: To conduct a systematic review and meta-analysis comparing physical function and complications following DIATF surgery with external fixation (EF) or open reduction internal fixation (ORIF).

Method: A search was conducted using PubMed, Embase, Cochrane CENTRAL, Open Grey and Orthopaedic Proceedings. Studies with a level of evidence of I-III on patients (≥ 18 years) with DIATFs operated on with either EF or ORIF were included. Read More

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http://dx.doi.org/10.1007/s00590-019-02368-9DOI Listing
February 2019

Polyglactin 910 suture compared with polyglactin 910 coated with triclosan in dental implant surgery: randomized clinical trial.

Int J Oral Maxillofac Surg 2019 Feb 6. Epub 2019 Feb 6.

Oral and Maxillofacial Surgery Department, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Antibacterial coating of surgical sutures is a suggested approach to prevent surgical site infections. The aim of this study was to compare the incidence of surgical site infection following the use of polyglactin 910 (Vicryl) and polyglactin 910 coated with triclosan (Vicryl Plus) sutures in dental implant surgery. This single-blind, randomized clinical trial evaluated patients who received three implants in the posterior mandible. Read More

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http://dx.doi.org/10.1016/j.ijom.2019.01.011DOI Listing
February 2019