84,553 results match your criteria Wound Infection


Impact of closed-incision negative pressure wound dressings on surgical site infection following groin incisions in vascular surgery; a single-centre experience.

Vascular 2022 Jun 27:17085381221111007. Epub 2022 Jun 27.

Department of Vascular Surgery, Fiona Stanley Hospital, Perth, WA, Australia.

Objectives: Surgical site infection (SSI) is a common complication in vascular surgery, and is associated with increased patient morbidity, readmission and reintervention. The aim of this study was to assess the impact of closed-incision negative pressure wound therapy (CiNPWT) upon rate of SSI and length of hospital stay.

Methods: This study was reported in line with the STROBE guidelines. Read More

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Planar-/Curvilinear-Bioprinted Tri-Cell-Laden Hydrogel for Healing Irregular Chronic Wounds.

Adv Healthc Mater 2022 Jun 27:e2201021. Epub 2022 Jun 27.

Institute of Polymer Science and Engineering, National Taiwan University, No. 1, Sec. 4 Roosevelt Road, Taipei, 10617, Taiwan.

Chronic cutaneous wounds from tissue trauma or extensive burns could impair skin barrier function and cause severe infection. Fabrication of a customizable tissue-engineered skin is a promising strategy for regeneration of uneven wounds. Herein, we developed a planar-/curvilinear-bioprintable hydrogel to produce tissue-engineered skin and evaluated in rat models of chronic and irregular wounds. Read More

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A forgotten double-J ureteral stent resulting in an emphysematous perinephric abscess: A case report.

Medicine (Baltimore) 2022 Jun 24;101(25):e29418. Epub 2022 Jun 24.

Department of Internal Medicine, HANSUNG Union Internal Medicine Clinic and Dialysis Center, Daegu, Republic of Korea.

Rationale: Double-J stents (DJSs) are urologic devices widely used for urinary tract obstruction treatment. Perinephric abscess is a condition with purulent accumulation resulting from urinary tract infection retained between the renal capsule and Gerota's fascia. Emphysematous urinary tract infection in patients with a forgotten DJS is extremely rare. Read More

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Comparison of surgical morbidities between LigaSure™ and conventional techniques in inguinal or ilioinguinal lymph node dissection for skin cancer: A single center retrospective study.

J Dermatol 2022 Jun 27. Epub 2022 Jun 27.

Department of Skin Oncology/Dermatology, Saitama Medical University International Medical Center, Saitama, Japan.

Skin cancer patients with clinical nodal disease or whose positive sentinel nodes had great tumor burden remain candidates for regional lymph node dissections. Among these patients, inguinal or ilioinguinal lymph node dissection is frequently required in clinical practice, which is associated with significant postoperative morbidity-including lymphatic leakage. The aim of this retrospective study was to evaluate the efficacy of LigaSure™, an electrothermal bipolar vessel sealing system, in reducing lymphatic leakage in inguinal or ilioinguinal lymph node dissection. Read More

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Construction of multifunctional wound dressings with their application in chronic wound treatment.

Biomater Sci 2022 Jun 27. Epub 2022 Jun 27.

National Engineering Research Center for Biomaterials, Chuanda-Jinbo Joint Research Center, Sichuan University, Chengdu, 610064, China.

As the prevalence of diabetes increases year by year and the aging population continues to intensify in the world, chronic wounds such as diabetic foot ulcers and pressure ulcers have become serious problems that threaten people's health, and have brought an enormous burden to the world healthcare system. Conventional clinical treatment of chronic wounds relies on non-specific topical care (including debridement, infection/inflammation control, and frequent wound dressing changes), which can alleviate disease progression and reduce patient suffering to a certain extent, but the overall cure rate is less than 50% and the recurrence rate is high. Traditional wound dressings such as gauze, hydrocolloids, films and foams are single-function, acting as a physical barrier or absorbing exudates, and cannot meet all the needs of the entire chronic wound healing process. Read More

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Lower Extremity Salvage in a Diabetic Patient With Cutaneous Mucormycosis and COVID-19 After Open Patella Fracture.

Ochsner J 2022 ;22(2):163-168

Department of Plastic Surgery, Intermountain Medical Center, Murray, UT.

Cutaneous mucormycosis, while less common than sinonasal or pulmonary infections, can cause widespread tissue necrosis after seemingly innocuous encounters. The most common location of cutaneous mucormycosis is the extremities, and extensive infection has been reported after trauma or orthopedic procedures. A 60-year-old female with poorly controlled type 2 diabetes mellitus sustained an open patella fracture after a fall. Read More

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January 2022

Surgical Site Infection Following Single-Port Appendectomy: A Systematic Review of the Literature and Meta-Analysis.

Front Surg 2022 8;9:919744. Epub 2022 Jun 8.

Department of General, Visceral, Transplantation, Vascular and Pediatric Surgery, University Hospital, University of Wuerzburg, Wuerzburg, Germany.

Introduction: Surgical site infections (SSIs) are one of the most common postoperative complications after appendectomy leading to recurrent surgery, prolonged hospital stay, and the use of antibiotics. Numerous studies and meta-analyses have been published on the effect of open versus conventional laparoscopic appendectomy (CLA) reporting faster postoperative recovery and less postoperative pain for CLA. A development from CLA has been the single-port appendectomy (SPA), associated with a better cosmesis but seemingly having a higher risk of wound infections. Read More

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Identification of Important Modules and Biomarkers That Are Related to Immune Infiltration Cells in Severe Burns Based on Weighted Gene Co-Expression Network Analysis.

Front Genet 2022 9;13:908510. Epub 2022 Jun 9.

Department of Burns and Plastic and Wound Repair Surgery, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.

Immunosuppression is an important trigger for infection and a significant cause of death in patients with severe burns. Nevertheless, the prognostic value of immune-related genes remains unclear. This study aimed to identify the biomarkers related to immunosuppression in severe burns. Read More

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Sutureless socket technique after removal of third molars: a multicentric, open, randomized controlled trial.

BMC Oral Health 2022 Jun 26;22(1):256. Epub 2022 Jun 26.

Service de Chirurgie Orale, Department of Oral Surgery, CHU Nîmes, CHRU de Nîmes - Hôpital Universitaire Carémeau, University of Montpellier, Place du Professeur Debré, 30029, Nîmes Cedex 9, France.

Background: Although wisdom-tooth extraction is a routine intervention, the postoperative period remains marked by local inflammation classically manifesting as pain, edema and trismus. Furthermore, there is no consensus on the best operative techniques, particularly for the mucosal closure stage on impacted mandibular wisdom teeth.

Methods: This parallel, randomized, non-blinded study compared pain following removal of impacted third molars, with and without sutures. Read More

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Current status of interventional therapy for pulmonary emphysema with bronchoscopy.

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2022 May;47(5):665-672

Department of Respiratory Medicine, Branch of National Clinical Research Center for Respiratory Disease, Xiangya Hospital, Central South University, Changsha 410008.

Pulmonary emphysema is one of phenotypes of lung disease that can progress to chronic obstructive pulmonary disease (COPD). The pathogenesis is unknown, which may be closely related to smoking, infection, gene mutation, and air pollution. Pathological features of emphysema include the decreased airway elasticity at the distal end of the bronchioles and over-hyperinflation. Read More

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A case report of Actinomyces-associated vulvar necrotizing soft tissue infection: Aspects of multidisciplinary care.

Int J Surg Case Rep 2022 Jun 14;96:107314. Epub 2022 Jun 14.

Rochester General Hospital, Department of OBGYN, 1425 Portland Ave., Rochester, NY, 14621, United States of America. Electronic address:

Introduction And Importance: Necrotizing soft-tissue infections are life-threatening infections with significant morbidity and mortality.

Case Presentation: A 36-year-old female gravida 1 para 1001 with a history of intravenous drug use and homelessness presented to the emergency department for a three-day history of labial pain, swelling, and fevers. A contrast tomography scan revealed necrotizing soft tissue infection of the mons and vulva with subcutaneous gas. Read More

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Impact of systemic health on treatment outcomes in endodontics.

Int Endod J 2022 Jun 26. Epub 2022 Jun 26.

Endodontic Section, Department of Preventive and Restorative Dentistry, School of Dentistry, São Paulo State University (Unesp), R. José Bonifácio 1193, 16015-060-Araçatuba, São Paulo, Brazil.

The ultimate objective of root canal treatment (RCT) is the complete healing of periapical disease, with the restoration of tooth function. The healing of periapical lesions after RCT is not the result of the curative action of the treatment. The process of healing begins with inflammation, and is resolved by the clearance of the immunogen that induces the immune response. Read More

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Mini-plate versus reconstruction bar fixation for oncologic mandibular reconstruction with free fibula flaps: A systematic review and meta-analysis.

J Plast Reconstr Aesthet Surg 2022 May 6. Epub 2022 May 6.

Section of Plastic and Reconstructive Surgery, Memorial Sloan Kettering Cancer Center, NY, USA; Head and Neck Service, Memorial Sloan Kettering Cancer Center, NY, USA. Electronic address:

Introduction There is currently no consensus as to the comparative complication profiles of mini-plate (MP) and reconstruction bar (RB) osseous fixation in fibula flap mandibular reconstruction. The aim of this study is to compare complication rates associated with the use of MP versus RB fixation for vascularized fibula free flap (FFF) reconstruction of oncologic mandibular defects in an effort to better guide hardware utilization and pre-operative virtual surgical planning methods. Methods A systematic review and meta-analysis was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Read More

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Colistimethate sodium-chitosan hydrogel for treating Gram-negative bacterial wound infections.

Int J Biol Macromol 2022 Jun 22. Epub 2022 Jun 22.

Centre for Nanosciences and Molecular Medicine, Amrita Vishwa Vidyapeetham, Kochi 682041, India. Electronic address:

The drug resistance is higher among Gram-negative bacteria and demands the usage of strong antibiotics which can in turn result in systemic toxicity. In the treatment of the chronic wounds harboring pathogenic Gram-negative bacteria, the demand for an antimicrobial product that can be topically administered has been on the rise. In an effort to address the above issue, we have developed Colistimethate sodium (a high-end antibiotic) loaded chitosan hydrogel and characterized. Read More

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In-situ synthesis silver nanoparticles in chitosan/Bletilla striata polysaccharide composited microneedles for infected and susceptible wound healing.

Int J Biol Macromol 2022 Jun 22. Epub 2022 Jun 22.

Institute of Burn Research, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, PR China. Electronic address:

A novel antibacterial strategy is urgently required to develop for solving bacterial biofilm obstruction and bacterial drug resistance in the infected wound healing process. Herein, the Chitosan/Bletilla striata polysaccharide composited microneedles were prepared by chitosan, tannic acid, AgNO and Bletilla striata polysaccharide through step centrifugation. In our design system, the porous structure of microneedles gradually disappeared, and the mechanical properties were significantly improved after multiple fillings. Read More

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Long-term follow-up of the inside-out technique for treatment of preauricular sinuses: observational study.

Eur Arch Otorhinolaryngol 2022 Jun 25. Epub 2022 Jun 25.

Otorhinolaryngology-Head and Neck Surgery, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.

Purpose: This long-term follow-up study aims to externally validate the inside-out technique for surgical treatment of preauricular sinuses.

Methods: We analyzed the medical records of all patients who underwent the IO procedure at University Hospitals Leuven from 1 November 2005 to 30 November 2019 (N = 110). We were able to contact 77 of these 110 patients for a telephone interview, where we used a standardized questionnaire to evaluate recurrence, patient satisfaction and aesthetic result. Read More

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Tumor-Targeted Injectable Double-Network Hydrogel for Prevention of Breast Cancer Recurrence and Wound Infection via Synergistic Photothermal and Brachytherapy.

Adv Sci (Weinh) 2022 Jun 25:e2200681. Epub 2022 Jun 25.

Key Laboratory of Radiopharmacokinetics for Innovative Drugs, Chinese Academy of Medical Sciences, and Institute of Radiation Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, 300192, China.

The high locoregional recurrence rate and potential wound infection in breast cancer after surgery pose enormous risks to patient survival. In this study, a polyethylene glycol acrylate (PEGDA)-alginate double-network nanocomposite hydrogel (GPA) embedded with I-labeled RGDY peptide-modified gold nanorods ( I-GNR-RGDY) is fabricated. The double-network hydrogel is formed by injection of GPA precursor solutions into the cavity of resected cancerous breasts of mice where gelation occurred rapidly. Read More

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Necrotizing Fasciitis In A Patient with Metastatic Clear Cell Ovarian Carcinoma Treated with Bevacizumab.

Am J Case Rep 2022 Jun 25;23:e935584. Epub 2022 Jun 25.

Department of Internal Medicine, BronxCare Hospital, Affiliated with Icahn School of Medicine at Mount Sinai, Bronx, NY, USA.

BACKGROUND Necrotizing fasciitis is a life-threatening infection of the deep soft tissues that leads to progressive destruction of the fascia and subcutaneous fat. It typically spreads along the muscle fascia planes because of the relatively poor blood supply. Muscle tissue is usually spared because of its better blood supply. Read More

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Microbiology of surgical site infection in closed upper limb fractures: Data from a prospective trauma registry.

J Pak Med Assoc 2022 Jun;72(6):1184-1187

Department of Surgery, Aga Khan University, Karachi, Pakistan.

The current study aims to determine the rate of surgical site infection, causal microorganism, and antibiotic sensitivity pattern in operated upper limb closed fractures at the Aga Khan University Hospital, Karachi. Cases presenting between June 2015 to October 2019, were selected from a single-centre, longitudinal, prospective orthopaedic trauma registry. Infection rate, causal microorganism, and antibiotic sensitivity pattern were determined up to six months after surgery. Read More

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Combined anterior and posterior ring fixation versus posterior ring fixation alone in the management of unstable Tile B and C pelvic ring injuries: A randomized controlled trial.

Chin J Traumatol 2022 Jun 15. Epub 2022 Jun 15.

Department of Orthopedics and Traumatology, Faculty of Medicine, Ain Shams University, Cairo, 11522, Egypt.

Purpose: Combined anterior and posterior ring (APR) fixation is classically performed in Tile B2 and C1 injuries to achieve superior biomechanical stability. However, the posterior ring (PR) is the main weight bearing portion that is responsible for weight transmission from the upper parts of the body to the lower limbs through the sacrum and the linea terminalis. It is hypothesized that isolated PR fixation can achieve comparable radiological and clinical outcomes to APR fixation. Read More

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Chitosan-based composites reinforced with antibacterial flexible wood membrane for rapid hemostasis.

Int J Biol Macromol 2022 Jun 21;215:450-464. Epub 2022 Jun 21.

State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, PR China. Electronic address:

Irregular hemorrhagic traumas always threaten the health of patients due to uncontrollable bleeding and wound infections. The traditional hemostatic materials show dissatisfactory hemostatic efficiency and antibacterial activity in solving these potential bleeding dangers. Herein, we proposed a kind of composites based on flexible wood membrane (FWM) loaded with chitosan/alginate derivative for accelerating rapid hemostasis and preventing infection. Read More

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Do sclero-embolization procedures have advantages over surgical ligature in treating varicocele in children, adolescents and adults? Results from a systematic review and meta-analysis.

Andrologia 2022 Jun 24:e14510. Epub 2022 Jun 24.

Urology Unit, Azienda Ospedaliero-Universitaria Ospedali Riuniti di Ancona, Polytechnic University of the Marche Region, Ancona, Italy.

We aimed to systematically review complications, and recurrence rate of varicocele treatment by comparing the surgical ligature versus sclero-embolization techniques in children, adolescents and adults. The secondary outcomes were the evaluation of semen parameters and spontaneous pregnancy rate in adults. The review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses framework. Read More

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A Novel Non-Antibiotic Gut-Directed Strategy to Prevent Surgical Site Infections.

Ann Surg 2022 Jun 28. Epub 2022 Jun 28.

University of Chicago, Chicago, IL.

Objective: Determine the efficacy of an orally delivered phosphate rich polymer, Pi-PEG, to prevent surgical site infection (SSI) in a mouse model of spontaneous wound infection involving gut-derived pathogens.

Summary Background Data: Evidence suggests that pathogens originating from the gut microbiota can cause postoperative infection via a process by which they silently travel inside an immune cell and contaminate a remote operative site (Trojan Horse Hypothesis). Here we hypothesize that Pi-PEG can prevent SSIs in a novel model of postoperative SSIs in mice. Read More

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The problem of the risk of development of infection of surgical obstetric wound after cesarian section in women of the Kirov region.

Klin Lab Diagn 2022 Jun;67(6):374-379

Kirov State Medical University.

Over the past decade, the frequency of abdominal delivery in Russia has increased to an average of 25 %. The widespread use of abdominal delivery has not been without an increase in the incidence of complications. Among them is an infectious complication of a surgical obstetric wound (ICD O86. Read More

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Periocular non-tuberculous mycobacterial infection after autologous fat transfer with micro-needling and fractional radiofrequency skin resurfacing.

Orbit 2022 Jun 24:1-3. Epub 2022 Jun 24.

Consultants in Ophthalmic and Facial Plastic Surgery, P.C, Southfield, MI, USA.

A 59-year-old woman with prior bilateral lower eyelid autologous fat transfer, subdermal micro-needling and fractional radiofrequency skin resurfacing presented with delayed left-sided preseptal cellulitis with small multinodular abscesses unresponsive to oral outpatient antibiotic regimens and inpatient intravenous antibiotics. Wound culture revealed infection treated successfully with a 4-month regimen of clarithromycin and tedizolid without recurrence. This case highlights (1) the need for vigilance and a broad differential in delayed post-operative wound infections including non-tuberculous mycobacterial infections, (2) resolution of infection without recurrence on clarithromycin and novel tedizolid oral antibiotic therapy, and (3) that caution should be exercised when performing combination autologous fat transfers with subdermal micro-needling procedures as the breakdown in skin integrity may potentiate infection. Read More

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Prophylactic mesh placement in emergency midline laparotomy for intestinal perforation peritonitis: An appeal for caution.

Trop Doct 2022 Jun 23:494755221110831. Epub 2022 Jun 23.

Department of Surgery, 534313NSCB Government Medical College, Jabalpur, India.

Prophylactic mesh placement (PMP) is increasingly being used to reduce the incidence of incisional hernia after routine and emergency midline laparotomy (EML). However, such studies are not available for EMLs done solely for intestinal perforation. Patients who underwent non-absorbable PMP during EML for intestinal perforation (Group A, 15 patients) were compared with those who had a conventional abdominal wall closure (Group B, 20 patients). Read More

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Post-cesarean severe sepsis and uterine wound disruption presenting as abdominal wound abscess and peritonitis: A case report.

SAGE Open Med Case Rep 2022 16;10:2050313X221105922. Epub 2022 Jun 16.

Department of Obstetrics and Gynaecology, Faculty of Postgraduate Medicine, Khesar Gyalpo University of Medical Sciences of Bhutan, Thimphu, Bhutan.

With increasing rate of cesarean section in Bhutan, the complications are expected to rise. Uterine scar dehiscence is one of the immediate complications of cesarean section, which has high morbidity and mortality. Herein, we report a case of uterine wound dehiscence with pelvic abscess following cesarean section, who presented with paralytic ileus and surgical site infection. Read More

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An Evaluation of the Effect of the Use of N95 Respirators by Surgical Teams on Early Surgical Site Infections in Orthopedic Cases.

Cureus 2022 May 19;14(5):e25138. Epub 2022 May 19.

Orthopaedics and Traumatology, Hitit University Corum Erol Olcok Training and Research Hospital, Corum, TUR.

Background Surgical site infections (SSIs) are seen in the postoperative period in orthopedic and traumatology clinics. Just as in all surgical clinics, SSIs lead to patient dissatisfaction with the results, prolong the length of stay in the hospital, and increase treatment costs. SSIs are known to occur as a result of wound contamination through inoculation of microorganisms found mainly in the air or in the surgical area. Read More

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Management of Idiopathic Pyoderma Gangrenosum With Azathioprine As the Primary Adjunct in an Asian Man: A Case Report.

Cureus 2022 May 21;14(5):e25177. Epub 2022 May 21.

Medicine, Jinnah Hospital, Allama Iqbal Medical College, Lahore, PAK.

Pyoderma gangrenosum (PG) is a very rare, non-infectious, progressive inflammatory condition falling under the umbrella of neutrophilic dermatoses. It is an ulcerative condition with a wide variety of cutaneous manifestations and multiple clinical variants (classic ulcerative, pustular, bullous, and superficial granulomatous). Additionally, owing to similar patterns of mucocutaneous ulceration, it has certain overlaps with other neutrophilic diseases frequently observed in clinical practice. Read More

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A Novel Approach Combined with MIPO Technique for the Treatment of Type C Pilon Fractures.

Oxid Med Cell Longev 2022 14;2022:7427255. Epub 2022 Jun 14.

Department of Orthopedics, Chongqing University Three Gorges Hospital, Chongqing 404000, China.

Objective: Type C fracture is a complete intra-articular fracture, and the mainstay of treatment remains open reduction and internal fixation. The purpose of the study is to observe the clinical effect of an anterior ankle C approach (ankle-C) combined with minimal invasive plate osteosystems (MIPO) for tibial pilon fractures (AO/OTA 43C, combined with fibula fractures).

Methods: A retrospective comparative analysis was performed on the clinical data of 33 patients with C-type pilon fractures (combined fibula fractures) admitted to our department from July 2018 to July 2021, including 12 cases treated with ankle-C (a-C) approach and 21 cases with conventional approach (including combined approach). Read More

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