79,859 results match your criteria Wound Infection


External validation of a predictive model of adverse events following spine surgery.

Spine J 2021 Jun 8. Epub 2021 Jun 8.

Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA.

Background Context: We lack models that reliably predict 30-day postoperative adverse events (AEs) following spine surgery.

Purpose: We externally validated a previously developed predictive model for common 30-day adverse events (AEs) after spine surgery.

Study Design/setting: This prospective cohort study utilizes inpatient and outpatient data from a tertiary academic medical center. Read More

View Article and Full-Text PDF

Safety in Dermatologic Procedures: How to Prevent, Recognize, and Treat Bleeding Complications in Dermatologic Surgery.

Actas Dermosifiliogr 2021 Jun 8. Epub 2021 Jun 8.

Servicio de Dermatología. Complejo Hospitalario de Navarra, Pamplona, España.

Bleeding complications during dermatologic surgery are uncommon and usually minor, but bleeding occasionally leads to infection, wound dehiscence, or flap/graft necrosis. This review covers the keys to preventing, recognizing, and treating excessive bleeding during and after surgery. Read More

View Article and Full-Text PDF

Prophylactic dialysis improves short-term clinical outcome in patients with non-dialysis-dependent chronic kidney disease undergoing cardiac surgery: a meta-analysis of randomized controlled trials.

Coron Artery Dis 2021 Jun 10. Epub 2021 Jun 10.

Division of Nephrology, Beijing Anzhen Hospital, Capital Medical University, Beijing, P.R.China.

Background: Several studies have reported that prophylactic dialysis can reduce the mortality of non-dialysis-dependent chronic kidney disease (CKD) patients after cardiac surgery. However, the results of complications in these randomized controlled trials (RCTs) were not consistent. We aimed to perform a meta-analysis to systematically evaluate the effect of prophylactic dialysis in these non-dialysis-dependent CKD patients. Read More

View Article and Full-Text PDF

Closed non-suction drain placement as haematoma and seroma formation preventive measure post-nylon darn surgery for inguinoscrotal hernias in adults.

Hernia 2021 Jun 11. Epub 2021 Jun 11.

Department of Medical Laboratory Sciences, School of Biomedical and Allied Health Sciences, University of Ghana, Korle, Bu, Accra, Ghana.

Purpose: Inguinal hernia is a common male surgical disease. Intervention carries a wide range of complications such as scrotal haematoma and seroma which may require surgical re-intervention or predispose patients to developing infections, pains or feeling of mass. This could lead to long hospital stay. Read More

View Article and Full-Text PDF

Therapeutic efficacy of arthroscopy-assisted transosseous fixation with the Versalok suture anchor for tibial eminence fractures in adults.

Medicine (Baltimore) 2021 Jun;100(23):e26284

Department of Orthopedics, Second Affiliated Hospital of Soochow University, No.1055 Sanxiang Road, Suzhou.

Abstract: To investigate the clinical outcomes of arthroscopy-assisted transosseous fixation of tibial eminence fractures with the Versalok suture anchor in adults.A total of 23 adult cases of tibial eminence fractures treated between June 2016 and March 2019 were retrospectively analyzed. The results of the preoperative drawer test and Lachman test were positive. Read More

View Article and Full-Text PDF

Retrospective study of the efficacy of vascularized tissue transfer for treating antibiotic-resistant bacteria-infected wound: Comparison with clean and antibiotic-sensitive bacteria-infected wound.

Medicine (Baltimore) 2021 Jun;100(23):e25907

Department of Plastic and Reconstructive Surgery, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul.

Abstract: If wounds are infected with bacteria resistant to an empirical antibiotic regimen, effective wound treatment will be delayed. This can delay wound healing and lengthen hospital stays, increasing the costs to patients. Long-term antibiotic use can also result in minor and major complications, such as diarrhea, antibiotic resistance, or life-threatening leukopenia. Read More

View Article and Full-Text PDF

Comparison of Antibacterial Activity and Wound Healing in a Superficial Abrasion Mouse Model of Skin Infection Using Photodynamic Therapy Based on Methylene Blue or Mupirocin or Both.

Front Med (Lausanne) 2021 25;8:673408. Epub 2021 May 25.

Department of Microbiology, Hospital Universitario Miguel Servet, IIS Aragón, Zaragoza, Spain.

Antibiotic resistance and impaired wound healing are major concerns in superficial skin infections, and new therapies are needed. Antimicrobial photodynamic therapy (aPDT) is a new therapeutic approach for infections, but it also improves healing in many wound models. To compare the antimicrobial activity and the effects on wound healing of aPDT based on Methylene Blue (MB-aPDT) with mupirocin treatment, either alone or in combination, in superficial skin wounds of -infected mice. Read More

View Article and Full-Text PDF

Canibacter oris - a fairly unknown pathogenic agent of bite wound infections.

GMS Infect Dis 2021 22;9:Doc01. Epub 2021 Apr 22.

Sankt Vincentius Krankenhaus, Klinik für Rekonstruktive und Plastische Chirurgie, Handchirurgie, Speyer, Germany.

Here, we report on the second case of bite wound infection by . This bacterium belongs to the family of in the order of in the class of , which are prevalent in the oral flora. Possibly this bacterium has been overlooked until now, because it cannot be recognized by conventional differentiation methods. Read More

View Article and Full-Text PDF

Follow the Shoestring: A Unique Case of Bullet Extraction.

Cureus 2021 May 5;13(5):e14862. Epub 2021 May 5.

Emergency Medicine, Saint Louis University School of Medicine, St. Louis, USA.

Firearm-related injuries and deaths remain a major issue in the United States. Gunshot injuries to the foot can be particularly difficult to manage when they occur as they can cause fractures or devastating neurovascular damage. There are limited reasons for routine bullet removal in most cases. Read More

View Article and Full-Text PDF

Surgical site infection prevention and management in immunocompromised patients: a systematic review of the literature.

World J Emerg Surg 2021 Jun 10;16(1):33. Epub 2021 Jun 10.

General, Emergency and Trauma Surgery Department, Pisa University Hospital, Via Paradisa 1, 56100, Pisa, Italy.

Background: Immunocompromised patients are at higher risk of surgical site infection and wound complications. However, optimal management in the perioperative period is not well established. Present systematic review aims to analyse existing strategies and interventions to prevent and manage surgical site infections and other wound complications in immunocompromised patients. Read More

View Article and Full-Text PDF

Characterisation of baseline microbiological and host factors in an inception cohort of people with surgical wounds healing by secondary intention reveals circulating IL-6 levels as a potential predictive biomarker of healing.

Wellcome Open Res 2020 19;5:80. Epub 2020 Nov 19.

York Biomedical Research Institute, Hull York Medical School, University of York, York, YO10 5DD, UK.

More than 2 million people per year are treated for surgical wounds in the UK.  Over a quarter of these wounds are estimated to heal by secondary intention (from the "bottom up") resulting in further complications and requiring increased healthcare resources. Identification of microbiological or host biomarkers that can predict healing outcomes may help to optimize the management of surgical wounds healing by secondary intention. Read More

View Article and Full-Text PDF
November 2020

Protein signatures of remodeled airways in transplanted lungs with Bronchiolitis Obliterans Syndrome obtained using laser capture microdissection.

Am J Pathol 2021 Jun 7. Epub 2021 Jun 7.

Lung Biology Unit, Department of Experimental Medical Science, Lund University, Lund, Sweden. Electronic address:

Bronchiolitis obliterans syndrome (BOS), a common form of chronic lung allograft dysfunction, is the major limitation to long-term survival after lung transplantation. The histological correlate is progressive, fibrotic occlusion of small airways, obliterative bronchiolitis lesions, ultimately leading to organ failure. The molecular composition of these lesions is unknown. Read More

View Article and Full-Text PDF

Use of incisional preventive negative pressure wound therapy in open incisional hernia repair: Who benefits?

Wound Repair Regen 2021 Jun 10. Epub 2021 Jun 10.

Department of General, Visceral, Vascular, and Transplantation Surgery, University Medical Center Rostock, Rostock, Germany.

Complex surgery of abdominal wall hernia continues to bear the major concern of wound healing disorders. Technical modifications have not been able to sufficiently prevent wound healing impairments or infections, even in clean elective cases, especially when dealing with large-scale hernia defects. Incisional negative pressure wound therapy (iNPWT) in its intentional use as a preventive tool has recently found its way from theoretical and experimental advantages to the clinical routine. Read More

View Article and Full-Text PDF

30-Day Outcomes for Total Ankle Arthroplasty in Patients With Anemia.

Foot Ankle Int 2021 Jun 10:10711007211017512. Epub 2021 Jun 10.

Department of Orthopedic Surgery, Mayo Clinic, Phoenix, AZ, USA.

Background: While anemia has been associated with poor surgical outcomes in total knee arthroplasty and total hip arthroplasty, the effects of anemia on total ankle arthroplasty remain unknown. This study examines how preoperative anemia affects postoperative outcomes in total ankle arthroplasty.

Methods: A retrospective analysis was performed using the American College of Surgeons National Surgery Quality Improvement Project database from 2011 to 2018 for total ankle arthroplasty procedures. Read More

View Article and Full-Text PDF

Incidence and Risk Factors of In-Hospital Prosthesis-Related Complications Following Total Knee Arthroplasty: A Retrospective Nationwide Inpatient Sample Database Study.

Orthop Surg 2021 Jun 9. Epub 2021 Jun 9.

Division of Orthopaedic Surgery, Department of Orthopaedics, Nanfang Hospital, Southern Medical University, Guangzhou, China.

Objective: To examine the incidence and risk factors of in-hospital prosthesis-related complications (PRCs) following total knee arthroplasty (TKA) using a large-scale national database.

Methods: A retrospective database analysis was performed based on Nationwide Inpatient Sample (NIS) from 2005-2014. Patients who underwent TKA were included. Read More

View Article and Full-Text PDF

Recent advances in the development of nitric oxide-releasing biomaterials and their application potentials in chronic wound healing.

J Mater Chem B 2021 Jun 10. Epub 2021 Jun 10.

Department of Histology and Embryology, NMPA Key Laboratory for Safety Evaluation of Cosmetics, School of Basic Medical Sciences, Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases, The Third Affiliated Hospital of Southern Medical University, Southern Medical University, Guangzhou, China.

Chronic wounds, such as pressure ulcers, vascular ulcers and diabetic foot ulcers (DFUs), often stay in a state of pathological inflammation and suffer from persistent infection, excess inflammation, and hypoxia, thus they are difficult to be healed. Nitric oxide (NO) plays a critical role in the regulation of various wound healing processes, including inflammatory response, cell proliferation, collagen formation, antimicrobial action and angiogenesis. The important role of NO in wound healing attracts intensive research focus on NO-based wound healing therapy. Read More

View Article and Full-Text PDF

Pursuit of the ideal antiseptic irrigation solution in the management of periprosthetic joint infections.

J Bone Jt Infect 2021 26;6(6):189-198. Epub 2021 May 26.

Brigham & Women's Hospital, Department of Orthopedics, Boston, MA, 02115, USA.

Irrigation and debridement in the treatment of periprosthetic joint infection (PJI) serve an integral role in the eradication of bacterial burden and subsequent re-infection rates. Identifying the optimal irrigation agent, however, remains challenging, as there is limited data on superiority. Direct comparison of different irrigation solutions remains difficult because of variability in treatment protocols. Read More

View Article and Full-Text PDF

Surgical Takedown Approaches to Insertional Achilles Tendinopathy: A Systematic Review.

J Foot Ankle Surg 2021 Apr 30. Epub 2021 Apr 30.

Fellowship-Trained Foot and Ankle Surgeon, Orthopedic Foot and Ankle Center, Worthington, OH.

Various techniques of surgical detachment for treatment of insertional Achilles tendinopathy have been described, including lateral release, medial release, central tendon splitting (CTS), and complete detachment. A systematic review of electronic databases was performed, encompassing 17 studies involving 703 patients and 746 feet, to compare outcomes associated with surgical takedown techniques. Observed results include wound complication rates (CTS 2. Read More

View Article and Full-Text PDF

Impact of surgical site infection on patients' outcome after fixation of tibial plateau fractures: a retrospective multicenter study.

BMC Musculoskelet Disord 2021 Jun 9;22(1):531. Epub 2021 Jun 9.

Department of Orthopedics, Trauma and Plastic Surgery, University of Leipzig, Liebigstraße 20, 04103, Leipzig, Germany.

Background: Surgical site infection (SSI) occurs in 3-10 % of patients with surgically treated tibial plateau fractures. This study aimed to evaluate the impact of SSI on patients' outcome after fixation of tibial plateau fractures.

Methods: We conducted a retrospective multicenter study in seven participating level I trauma centers between January 2005 and December 2014. Read More

View Article and Full-Text PDF

Waterjet in Bacterial Clearance of Diabetic Lower Extremity Contaminated Wounds: A Retrospective Cohort Study.

Int J Low Extrem Wounds 2021 Jun 9:15347346211024204. Epub 2021 Jun 9.

92323Zhongshan Hospital, Fudan University, Shanghai, China.

The waterjet debridement is now a standard practice in contaminated or infected diabetic lower extremity wounds. The bacterial clearance of the waterjet debridement remains an important parameter that should be predicted in this application. This study aimed to investigate the waterjet in reducing the diabetic lower extremity wound contaminants. Read More

View Article and Full-Text PDF

Wound infections: an overview.

Authors:
Martha Williams

Br J Community Nurs 2021 Jun;26(Sup6):S22-S25

Senior Tissue Viability Nurse, Community Tissue Viability Service, Oxford Health NHS Foundation Trust, Abingdon.

In the ever-changing world of wound care and nursing, it remains apparent that chronic wounds are a growing challenge. Evidence shows that age increases the likelihood of developing a chronic wound, which supports the notion that the burden of these wounds on the NHS is likely to further intensify with the ageing population. There are many reasons why a wound may fail to progress, including wound aetiology, comorbidities and environmental and socio-economic factors. Read More

View Article and Full-Text PDF

Prolonged antibiotic prophylaxis in tissue reconstruction using autologous fat grafting: Is there a benefit for wound healing?

Int Wound J 2021 Jun 9. Epub 2021 Jun 9.

Department of Plastic, Reconstructive and Aesthetic Surgery, Medical University of Innsbruck, Innsbruck, Austria.

Fat grafting is a well-established method in plastic surgery. Despite many technical advances, standardised recommendations for the use of prophylactic antibiotics in fat grafting are not available. This retrospective multicentre study aims to analyse the use of prophylactic antibiotics in fat grafting and to compare complication rates for different protocols. Read More

View Article and Full-Text PDF

Exploring prevalence of wound infections and related patient characteristics in homecare using natural language processing.

Int Wound J 2021 Jun 9. Epub 2021 Jun 9.

School of Nursing, Columbia University, New York City, New York, USA.

We aimed to create and validate a natural language processing algorithm to extract wound infection-related information from nursing notes. We also estimated wound infection prevalence in homecare settings and described related patient characteristics. In this retrospective cohort study, a natural language processing algorithm was developed and validated against a gold standard testing set. Read More

View Article and Full-Text PDF

Wildfire Burn Patients: A Unique Population.

J Burn Care Res 2021 Jun 9. Epub 2021 Jun 9.

Department of Surgery, Division of Burn Surgery, University of California, Davis, California.

In the past ten years wildfires have burned an average of 6.8 million acres per year and this is expected to increase with climate change. Wildfire burn patient outcomes have not been previously well characterized. Read More

View Article and Full-Text PDF

Nursing care of a newborn with deep incisional surgical site infection: a case report.

Rev Esc Enferm USP 2021 4;55:e03769. Epub 2021 Jun 4.

Hospital Infantil Waldemar Monastier, Campo Largo, PR, Brasil.

Objective: To describe a case of deep incisional surgical site infection in a children's hospital in South Brazil, emphasizing the nursing care measures provided to the newborn.

Method: Case study with data collection from medical record, approved by the institution and the Human Research Ethics Committee.

Results: From the diagnosis of surgical site infection, a plan was established for specific care of the lesion using occlusive dressings made with technologies aimed at accelerating the second-intention healing process. Read More

View Article and Full-Text PDF

When Is It Safe to Operate After Therapeutic Carpal Tunnel Injections?

Hand (N Y) 2021 Jun 9:15589447211017229. Epub 2021 Jun 9.

Emory University, Atlanta, GA, USA.

Background: Recent studies suggest increased complications when surgery closely follows corticosteroid injection. The purpose of this study was to understand the occurrence of surgical site infection (SSI), wound complications, and reoperation rates after carpal tunnel release (CTR) when corticosteroid injections were given within 180 days preoperatively.

Methods: Data were collected from the Truven MarketScan database from 2009 to 2018. Read More

View Article and Full-Text PDF

Mortality incidence among critically ill burn patients infected with multidrug-resistant organisms: A retrospective cohort study.

Scars Burn Heal 2021 Jan-Dec;7:20595131211015133. Epub 2021 May 25.

Critical Care Departement, Al-Wakra Hospital, Hamad Medical Corporation, Doha, Qatar.

Introduction: Many risk factors have been reported to increase mortality among burn patients. Previously, a higher mortality incidence was reported in acute burn patients infected with multidrug-resistant organisms (MDROs) when compared to patients infected with non-MDROs. However, considering this as an independent risk factor for mortality in acute burn patients is not yet confirmed. Read More

View Article and Full-Text PDF

The efficacy of single suture for exit site wound closure and stabilization of hemodialysis central tunneled catheter.

SAGE Open Med 2021 28;9:20503121211019889. Epub 2021 May 28.

Department of Nephrology and Internal Medicine, Institute of Medical Sciences, University of Opole, Opole, Poland.

Introduction: The majority of the end-stage renal disease patients begin hemodialysis with the central tunneled catheter as a permanent or bridge vascular access. The procedure of central tunneled catheter insertion can be complicated by exit site bleeding, prolonged tunnel healing, and infection. The study aimed at evaluating whether the catheter exit site wound closing with a single-suture method is equally effective as the double suture method, which is most frequently applied. Read More

View Article and Full-Text PDF

A review of animal models from 2015 to 2020 for preclinical chronic wounds relevant to human health.

J Tissue Viability 2021 Jun 1. Epub 2021 Jun 1.

Louis Stokes Cleveland Veterans Affairs Medical Center (LSCVAMC), Cleveland, OH, USA; Dept of Orthopaedics & Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA. Electronic address:

Significance: Chronic wounds fail to heal in a timely manner and exhibit sustained inflammation with slow tissue repair and remodelling. They decrease mobility and quality of life, and remain a major clinical challenge in the long-term care of many patients, affecting 6.5 million individuals annually in the U. Read More

View Article and Full-Text PDF

Perioperative Management of Antirheumatic Medications in Patients with RA and SLE Undergoing Elective Foot and Ankle Surgery: A Critical Analysis Review.

JBJS Rev 2021 06 8;9(6). Epub 2021 Jun 8.

Department of Orthopaedic Surgery, University of Michigan Health System, Ann Arbor, Michigan.

»: Recent literature has shown that continued use rather than discontinuation of various antirheumatic agents throughout the perioperative period may present an opportunity to mitigate the risks of elective surgery.

»: For patients with rheumatoid arthritis and systemic lupus erythematosus, perioperative management of medication weighs the risk of infection against the risk of disease flare when immunosuppressive medications are withheld.

»: Broadly speaking, current evidence, although limited in quality, supports perioperative continuation of disease-modifying antirheumatic drugs, whereas biologic drugs should be withheld perioperatively, based on the dosing interval of the specific drug. Read More

View Article and Full-Text PDF