71,406 results match your criteria Wound Infection


Negative Pressure versus Conventional Sternal Wound Dressing in Coronary Surgery Using Bilateral Internal Mammary Artery Grafts.

Heart Surg Forum 2019 Feb 25;22(2):E092-E096. Epub 2019 Feb 25.

Division of Cardiovascular and Thoracic Surgery, Robert Debré University Hospital, Reims, France.

Background: Sternal wound infection (SWI) is a major complication occurring often after coronary artery bypass grafting (CABG) using bilateral internal mammary artery (BIMA) grafts. The aim of this study is to assess whether such a risk may be reduced by using incision negative pressure wound therapy (INPWT).

Methods: Data on patients undergoing isolated CABG using BIMA grafts at the Reims University Hospital, France, from 2013 to 2016 without or with INPWT was prospectively collected. Read More

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http://dx.doi.org/10.1532/hsf.2269DOI Listing
February 2019

Local Photothermal/Photodynamic Synergistic Therapy by Disrupting Bacterial Membrane to Accelerate Reactive Oxygen Species Permeation and Protein Leakage.

ACS Appl Mater Interfaces 2019 Apr 23. Epub 2019 Apr 23.

Bacterial infection is still a ticklish clinical challenge even though some advanced antibacterial materials and techniques have been put forwardd. This work reports that rapid and effective antibacterial performance is achieved by the synergistic local photothermal and photodynamic therapy (PTDT). Within 10 min light irradiation, both Escherichia coli (E. Read More

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http://dx.doi.org/10.1021/acsami.9b05787DOI Listing

Assessment of complications following urinary diversion for benign indications.

Can J Urol 2019 Apr;26(2):9720-9725

Department of Urology, University of Virginia, Charlottesville, Virginia, USA.

Introduction: To evaluate complications following urinary diversion for non-malignant conditions.

Materials And Methods: We performed a retrospective review of patients undergoing urinary diversion for benign indications between 2000 and 2017. Data collected including patient demographic and clinical characteristics, surgical characteristics, and complications. Read More

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Corneal cross-linking (CXL)-A clinical study to evaluate CXL as a treatment in comparison with medical treatment for ulcerative keratitis in horses.

Vet Ophthalmol 2019 Apr 23. Epub 2019 Apr 23.

Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden.

Objective: Compare CXL treatment with medical treatment alone in horses with stromal, ulcerative keratitis.

Animals Studied: 24 horses (24 eyes) with stromal, ulcerative keratitis were included.

Procedure: 12 horses were initially treated with CXL, and 12 horses were given conventional medical treatment. Read More

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http://dx.doi.org/10.1111/vop.12662DOI Listing

Factors associated with blood culture positivity in patients with complicated skin and skin structure infection-a population-based study.

Eur J Clin Microbiol Infect Dis 2019 Apr 22. Epub 2019 Apr 22.

Department of Infectious Diseases, Inflammation Center, Helsinki University Hospital and University of Helsinki, P.O. Box 372, 00029 HUS, Helsinki, Finland.

Skin and skin structure infection (SSSI) is classified as complicated (cSSSI) if it involves deep subcutaneous tissue or requires surgery. Factors associated with blood culture sampling and bacteremia have not been established in patients with cSSSI. Moreover, the benefit of information acquired from positive blood culture is unknown. Read More

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http://dx.doi.org/10.1007/s10096-019-03560-9DOI Listing

Does peritrochanteric fat thickness increase the risk of early reoperation for infection or wound complications following total hip arthroplasty?

J Orthop 2019 Sep-Oct;16(5):359-362. Epub 2019 Apr 8.

Rush University Medical Center, Department of Orthopaedic Surgery, Chicago, IL, USA.

Background: Radiographically measured subcutaneous peri-incisional tissue depth has been correlated with post-operative surgical site infection after cardiac, cervical spine, and total knee surgery. Its impact following primary total hip arthroplasty (THA) has not been studied. We compare the interobserver reliability of measuring peritrochanteric fat thickness on pre-operative radiographs and hypothesize that these measurements are a reproducible way to predict acute post-operative wound complications and infection in patients undergoing THA. Read More

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http://dx.doi.org/10.1016/j.jor.2019.03.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461593PMC

Natural fiber reinforced biodegradable staples: Novel approach for efficient wound closure.

Med Hypotheses 2019 May 22;126:60-65. Epub 2019 Mar 22.

Department of Medical Devices, National Institute of Pharmaceutical Education and Research-Ahmedabad, Opp. Airforce Station, Gandhinagar, Gujarat 382355, India. Electronic address:

Every year millions of lacerations and incisions taken place and require an effective methodology to manage the wound for a better life. The primary causes include mechanical trauma and surgical procedures. The rapid healing of the wound is critical to prevent further infection and reduction pain etc. Read More

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http://dx.doi.org/10.1016/j.mehy.2019.03.021DOI Listing

"Closed-Incision Negative-Pressure Therapy Efficacy in Abdominal Wall Reconstruction in High-Risk Patients: A Meta-Analysis".

J Surg Res 2019 Apr 19;241:63-71. Epub 2019 Apr 19.

Division of Plastic and Reconstructive Surgery, Department of Surgery, Rutgers New Jersey Medical School, Newark, New Jersey. Electronic address:

Background: Obesity is a known risk factor for surgical complications. Closed-incision negative-pressure therapy (ciNPT) has been used anecdotally in high-risk patients to prevent wound complications and infection. This meta-analysis aims to evaluate the efficacy of ciNPT in reducing the incidence of wound complications and infection in abdominal wall reconstruction. Read More

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http://dx.doi.org/10.1016/j.jss.2019.03.033DOI Listing

A Retrospective Database Review of the Indications, Complications, and Incidence of Subsequent Spine Surgery in 12,297 Spinal Cord Stimulator Patients.

Neuromodulation 2019 Apr 22. Epub 2019 Apr 22.

Department of Orthopaedic Surgery, University of Virginia, Charlottesville, VA, USA.

Study Design: Retrospective review.

Objective: To analyze the indications, incidence of minor and major complications, and rate of subsequent spinal surgery or revision after spinal cord stimulator (SCS) placement for degenerative spine disease.

Summary Of Background Data: Despite the application of SCS in various chronic pain conditions, there remains a growing debate on the efficacy and necessity of SCS in degenerative spine disease. Read More

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http://dx.doi.org/10.1111/ner.12952DOI Listing

Autologous Platelet-Rich Plasma and Fibrin Glue Decrease Pain Following Excision and Primary Closure of Pilonidal Sinus.

Adv Skin Wound Care 2019 May;32(5):234-237

In the Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran, Daryoush Hamidi Alamdari, PhD, is Associate Professor of Biochemistry; Mohamad Reza Motie, MD, is Associate Professor of Surgery; Nasim Kamalahmadi, MD, is a Medical Practitioner; and Mohsen Aliakbarian, MD, is Associate Professor of Surgery. Acknowledgments: The authors thank the patients who participated in the study and Ms M. Hassanpour for editing the manuscript. The study was supported by the Vice Chancellor for Research of Mashhad University of Medical Sciences (grant 88529). The authors have disclosed no other financial relationships related to this article. Submitted April 24, 2018; accepted in revised form June 8, 2018.

Background: Pilonidal sinus is one of the most complicated chronic wounds common in younger adults. This disabling condition affects the natal clefts of the buttocks and often requires surgery.

Objective: To investigate the effect of autologous platelet-rich plasma and fibrin glue (PRP-FG) on pain reduction and the healing process of pilonidal sinus after excisional surgery with primary closure. Read More

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http://dx.doi.org/10.1097/01.ASW.0000550589.23921.45DOI Listing

Candy Closure Technique for Chronic Open Infective Lateral Malleolus Bursitis.

Biomed Res Int 2019 17;2019:5490139. Epub 2019 Mar 17.

Department of Foot and Ankle Surgery, Eulji Medical Center, Eulji University, 68 Hangeulbiseok-ro, Nowoungu, 01830 Seoul, Republic of Korea.

The aim of this study was to report the effectiveness of the Candy closure technique as a treatment for chronic open infective lateral malleolus bursitis. From June 2014 to March 2018, we performed the Candy closure technique as a treatment for chronic open infective lateral malleolus bursitis in nine patients without secondary operation. We first performed infectious tissue debridement to control infection, and if primary closure was not possible, we performed the Candy closure technique for small wounds. Read More

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https://www.hindawi.com/journals/bmri/2019/5490139/
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http://dx.doi.org/10.1155/2019/5490139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441521PMC
March 2019
1 Read

Clinical and Radiological Outcomes of Oblique Lateral Lumbar Interbody Fusion.

Cureus 2019 Feb 7;11(2):e4029. Epub 2019 Feb 7.

Neurosurgery, Inspired Spine Health, Minneapolis, USA.

Oblique lateral lumbar interbody fusion (OLLIF) is a novel operation for fusions of the lumbar spine from T12-S1. In OLLIF, the disk is approached from an oblique lateral angle guided by electrophysiological monitoring and biplanar fluoroscopy; the disk space is accessed through Kambin's triangle. We present perioperative, clinical, patient-reported and radiological outcomes from a series of 303 OLLIF procedures on 568 levels performed by the same surgeon. Read More

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http://dx.doi.org/10.7759/cureus.4029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453614PMC
February 2019

Comparison of Vacuum-Assisted Closure Therapy and Conventional Dressing on Wound Healing in Patients with Diabetic Foot Ulcer: A Randomized Controlled Trial.

Niger J Surg 2019 Jan-Jun;25(1):14-20

Department of Preventive and Social Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

Background: Vacuum-assisted closure (VAC) therapy has been shown to be beneficial in a variety of wounds. However, evidence of its benefit in diabetic foot ulcers (DFUs), especially with respect to Indian population, is sparse.

Methodology: This randomized controlled trial included DFUs of Wagner's Grades 1 and 2. Read More

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http://www.nigerianjsurg.com/text.asp?2019/25/1/14/253776
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http://dx.doi.org/10.4103/njs.NJS_14_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452767PMC
April 2019
1 Read

Association of pneumonia, wound infection and sepsis with clinical outcomes after acute traumatic spinal cord injury.

J Neurotrauma 2019 Apr 22. Epub 2019 Apr 22.

St. Michael's Hospital, Division of Neurosurgery, Toronto, Canada ;

Pneumonia, wound infections and sepsis (PWS) are the leading causes of acute mortality after traumatic spinal cord injury (SCI). However, the impact of PWS on neurological and functional outcomes is largely unknown. The present study analysed participants from the prospective North American Clinical Trials Network (NACTN) registry and the Surgical Timing in Acute SCI Study (STASCIS) for the association between PWS and functional outcome (assessed as Spinal Cord Independence Measure subscores for respiration and indoor ambulation) at 6 months postinjury. Read More

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http://dx.doi.org/10.1089/neu.2018.6245DOI Listing

Direct superior approach with standard instrumentation for total hip arthroplasty: safety and efficacy in a prospective 200-case series.

Hip Int 2019 Apr 21:1120700019843120. Epub 2019 Apr 21.

1 Academic Orthopaedic Unit, Papageorgiou General Hospital, Aristotle University Medical School, Thessaloniki, Greece.

Introduction: Direct Superior Approach (DSA) is a muscle sparing approach for total hip arthroplasty (THA) implemented using special instrumentation. There is a lack of information in the literature concerning DSA with standard instrumentation.

Materials And Methods: 238 patients were recruited for primary THA by a single surgeon from January 2016 until May 2017. Read More

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http://dx.doi.org/10.1177/1120700019843120DOI Listing

Limberg flap reconstruction for sacrococcygeal pilonidal sinus disease with and without acute abscess: Our experience and a review of the literature.

Arch Plast Surg 2019 Apr 20. Epub 2019 Apr 20.

Long Island Plastic Surgical Group, Garden City, NY, USA.

Background: The efficacy of Limberg flap reconstruction for pilonidal sinus with acute abscess remains unclear. This study aimed to compare outcomes after Limberg flap reconstruction for pilonidal sinus disease with and without acute abscess. A secondary objective was to perform a review of the literature on the topic. Read More

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http://dx.doi.org/10.5999/aps.2018.01312DOI Listing

Prior Hip Arthroscopy Increases Risk for Perioperative Total Hip Arthroplasty Complications: A Matched-Controlled Study.

J Arthroplasty 2019 Apr 1. Epub 2019 Apr 1.

Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC.

Background: Arthroscopic hip surgery is becoming increasingly popular for the treatment of femoroacetabular impingement and labral tears. Reports of outcomes of hip arthroscopy converted to total hip arthroplasty (THA) have been limited by small sample sizes. The purpose of this study was to investigate the impact of prior hip arthroscopy on THA complications. Read More

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http://dx.doi.org/10.1016/j.arth.2019.03.066DOI Listing

Percutaneous CT guided bone biopsy for suspected osteomyelitis: Diagnostic yield and impact on patient's treatment change and recovery.

Eur J Radiol 2019 May 8;114:85-91. Epub 2019 Feb 8.

Radiology, UT Southwestern Medical Center, Dallas, TX, USA; Orthopedics, UT Southwestern Medical Center, Dallas, TX, USA.

Aim: To evaluate the utility of percutaneous CT guided bone biopsy (PCBB) for suspected osteomyelitis (OM) and its eventual impact on patient management and recovery.

Material And Methods: Patients who received a PCBB for suspected osteomyelitis from years 2012-2018. Patient demographics, lesion location, ulcer grade, signs of toxemia, serology, wound and blood cultures, bone biopsy and cross-sectional imaging results were recorded. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.01.032DOI Listing

Effective Topical Delivery of H-AgNPs for Eradication of Klebsiella pneumoniae-Induced Burn Wound Infection.

AAPS PharmSciTech 2019 Apr 19;20(5):169. Epub 2019 Apr 19.

Division of Pharmaceutics, University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India.

The aim of the present study was to explore the therapeutic efficacy of microemulsion-based delivery of histidine-capped silver nanoparticles in eradicating Klebsiella pneumoniae-induced burn wound infection. The developed microemulsion was characterized on the basis of differential light scattering, phase separation, refractive index, and specific conductance. Emulgel was prepared and characterized on the basis of thixotropy, texture, differential scanning calorimetry, and release kinetics. Read More

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http://dx.doi.org/10.1208/s12249-019-1350-yDOI Listing

Obstetric perineal tears: risk factors, wound infection and dehiscence: a prospective cohort study.

Arch Gynecol Obstet 2019 Apr 19. Epub 2019 Apr 19.

Department of Gynaecology and Obstetrics, Odense University Hospital, J.B. Winsløws Vej 4, 5000, Odense C, Denmark.

Purpose: To assess risk factors for perineal tears, wound infection and dehiscence among primiparous women.

Methods: A prospective cohort study at four Danish hospitals (Odense, Esbjerg, Aarhus and Kolding) among 603 primiparous women sampled in three groups: 203 with none/labia/1st degree, 200 with 2nd degree, and 200 with 3rd/4th degree tears included between July 2015 and January 2018. Baseline data were obtained and a clinical examination of perineal wound healing was performed 11-21 days postpartum. Read More

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http://link.springer.com/10.1007/s00404-019-05165-1
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http://dx.doi.org/10.1007/s00404-019-05165-1DOI Listing
April 2019
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Total Hip Arthroplasty Through the Direct Anterior Approach Using a Bikini Incision Can Be Safely Performed in Obese Patients.

J Arthroplasty 2019 Apr 2. Epub 2019 Apr 2.

Rothman Orthopaedic Institute, Philadelphia, PA.

Background: Direct anterior approach (DAA) total hip arthroplasty can be performed through a traditional vertical incision or a horizontal (bikini) incision. The purpose of this study is to compare the 2 approaches, performed by a single surgeon past the learning curve, in terms of (1) overall wound complications and (2) patient-reported esthetics at the 6-month follow-up.

Methods: A case-control retrospective study was conducted. Read More

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http://dx.doi.org/10.1016/j.arth.2019.03.060DOI Listing

Gender Differences for Hip and Knee Arthroplasty: Complications and Healthcare Utilization.

J Arthroplasty 2019 Apr 1. Epub 2019 Apr 1.

Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL.

Introduction: The influence of patient gender on complications and healthcare utilization remains unexplored. The purpose of the present study was to determine if patient gender significantly affected outcomes following total hip arthroplasty (THA) and total knee arthroplasty (TKA).

Methods: Retrospective cohort study of THA and TKA patients was performed using the Nationwide Inpatient Sample from 2002 to 2011. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08835403193032
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http://dx.doi.org/10.1016/j.arth.2019.03.064DOI Listing
April 2019
1 Read

Clinical outcome of V-Y flap with latissimus dorsi and gluteal advancement for treatment of large thoracolumbar myelomeningocele defects: a comparative study.

J Neurosurg Pediatr 2019 Apr 19:1-10. Epub 2019 Apr 19.

1Department of Neurosurgery.

OBJECTIVESurgical repair and closure of myelomeningocele (MMC) defects are important and vital, as the mortality rate is as high as 65%-70% in untreated patients. Closure of large MMC defects is challenging for pediatric neurosurgeons and plastic surgeons. The aim of the current study is to report the operative characteristics and outcome of a series of Iranian patients with large MMC defects utilizing the V-Y flap and with latissimus dorsi or gluteal muscle advancement. Read More

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http://dx.doi.org/10.3171/2019.1.PEDS18232DOI Listing

The application of moist dressings in wound care for tracheostomy patients: a meta-analysis.

J Clin Nurs 2019 Apr 19. Epub 2019 Apr 19.

Neurology Department, Tianjin Huanhu Hospital, Tianjin.

Aim: This meta-analysis was to evaluate the clinical application of moist wound dressings in wound care for patients with the tracheostomy.

Background: Tracheostomy patients may suffer from many complications. Moist dressings have been proposed to lower complication rates for patients with the tracheostomy. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jocn.14885
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http://dx.doi.org/10.1111/jocn.14885DOI Listing
April 2019
1 Read

Soft tissue free flap for reconstruction of upper extremities: A meta-analysis on outcome and safety.

Microsurgery 2019 Apr 19. Epub 2019 Apr 19.

Department of Hand, Plastic, and Reconstructive Surgery, Microsurgery, Burn Center, BG Trauma Center, Department of Plastic and Hand Surgery, University of Heidelberg, Ludwigshafen, Germany.

Background: The aim of this study was to evaluate outcome and safety of free flaps to the upper extremity by pooled, summarized rates, compared with the existing pooled results of the lower extremity from literature, and to improve the level of evidence in a meta-analysis.

Methods: A literature search of PubMed and Embase was conducted addressing publications between January 2000 and April 2018. Publications were selected by inclusion/exclusion criteria on safety and outcome. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/micr.30460
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http://dx.doi.org/10.1002/micr.30460DOI Listing
April 2019
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Outbreak of Nontuberculous Mycobacteria Joint Prosthesis Infections, Oregon, USA, 2010-2016.

Emerg Infect Dis 2019 May;25(5):849-855

We investigated a cluster of Mycobacterium fortuitum and M. goodii prosthetic joint surgical site infections occurring during 2010-2014. Cases were defined as culture-positive nontuberculous mycobacteria surgical site infections that had occurred within 1 year of joint replacement surgery performed on or after October 1, 2010. Read More

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http://wwwnc.cdc.gov/eid/article/25/5/18-1687_article.htm
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http://dx.doi.org/10.3201/eid2505.181687DOI Listing
May 2019
1 Read

Clinical Experience with Hemopatch® as a Dural Sealant in Cranial Neurosurgery.

Cureus 2019 Feb 4;11(2):e4013. Epub 2019 Feb 4.

Department of Neurosurgery, University Medical Centre of Regensburg, Regensburg, DEU.

Background: Herein, we report our clinical experience with the novel polyethylene glycol-covered matrix dural onlay, Hemopatch® (Baxter Deutschland GmbH, Unterschleißheim, Germany) for the prevention of postoperative cerebrospinal fluid (CSF) fistulas.

Methods: Retrospectively, 22 consecutive patients (11 females, 11 males, mean age: 49.8 years, range: 15-77 years) with oncological and vascular intracranial lesions were included in this study. Read More

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https://www.cureus.com/articles/17296-clinical-experience-wi
Publisher Site
http://dx.doi.org/10.7759/cureus.4013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450590PMC
February 2019
2 Reads

Outcome of Islanded Gastrocnemius Musculocutaneous Flap in Orthopaedic Practice.

Malays Orthop J 2019 Mar;13(1):25-29

Department of Surgery, International Islamic University of Malaysia, Kuantan, Malaysia.

Large wounds in the leg require combination of local flaps or free flap for wound coverage. Gastrocnemius musculocutaneous flap (GMCF) allows a large wound to be covered by a single local flap. However, the conventional GMCF is often associated with donor site morbidity where the exposed soleus raphe causes poor uptake of the skin graft. Read More

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http://www.morthoj.org/2019/v13n1/islanded-gastrocnemius.pdf
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http://dx.doi.org/10.5704/MOJ.1903.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459037PMC
March 2019
1 Read

A systematic review of foam dressings for partial thickness burns.

Am J Emerg Med 2019 Apr 11. Epub 2019 Apr 11.

Department of Emergency Medicine, State University of New York, Downstate Medical Center, Brooklyn, NY, USA. Electronic address:

Background: Partial thickness burns are the most common form of thermal burns. Traditionally, dressing for these burns is simple gauze with silver sulfadiazine (SSD) changed on a daily basis. Foam dressings have been proposed to offer the advantage of requiring less frequent dressing change and better absorption of exudates. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07356757193023
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http://dx.doi.org/10.1016/j.ajem.2019.04.014DOI Listing
April 2019
1 Read

The Safety and Effectiveness of the Percutaneous Flexor Tenotomy in Healing Neuropathic Apical Toe Ulcers in the Outpatient Setting.

Foot Ankle Spec 2019 Apr 19:1938640019843314. Epub 2019 Apr 19.

Podiatry and Foot Ulcer/Charcot's Specialist Clinic, Austin Health, West Heidelberg, Victoria, Australia.

Percutaneous flexor tenotomy is a minimally invasive procedure that involves cutting one or both flexor digitorum tendons underneath the toe. It is an alternative to open surgical procedures performed in an operating theatre. This project is a prospective case series investigating the utility, effectiveness, and participant satisfaction of the percutaneous flexor tenotomy when performed in the outpatient setting. Read More

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http://dx.doi.org/10.1177/1938640019843314DOI Listing
April 2019
1 Read

Cost-Effectiveness of Negative Pressure Incision Management System in Cardiac Surgery.

J Surg Res 2019 Apr 15;240:227-235. Epub 2019 Apr 15.

Division of Thoracic & Cardiovascular Surgery, Department of Surgery, University of Virginia, Charlottesville, Virginia.

Background: Sternal wound infections (SWIs) can be a devastating long-term complication with significant morbidity and health care cost. The purpose of this analysis was to evaluate the cost-effectiveness of negative pressure incision management systems (NPIMS) in cardiac surgery.

Materials And Methods: All cardiac surgery cases at an academic hospital with risk scores available (2009-2017) were extracted from an institutional database (n = 4455). Read More

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http://dx.doi.org/10.1016/j.jss.2019.02.046DOI Listing

Rigid Primary Sternal Fixation Reduces Sternal Complications among Patients at Risk.

Ann Thorac Surg 2019 Apr 15. Epub 2019 Apr 15.

Department of Cardiac Surgery, Quebec Heart and Lung University Institute, Quebec City, Quebec, Canada. Electronic address:

Background: The optimal sternal closure technique in patients at elevated risk post-cardiac surgery has not been elucidated.

Methods: Between January 2006 and July 2015, 15,048 consecutive adult patients underwent cardiac surgery via median sternotomy using cardiopulmonary bypass. Rigid sternal fixation utilizing three separate techniques (peristernal poly-ether-ether-ketone (PEEK) banding, titanium plating, and stainless-steel multibraided cables with cannulated screws) was used in 1,111 patients (Group A); conventional peristernal/transsternal wiring was used in the remainder (Group B, n=13,937). Read More

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http://dx.doi.org/10.1016/j.athoracsur.2019.03.046DOI Listing

Silica Coated Gold-Silver Nanocages as Photothermal Antibacterial Agents for Combined Anti-Infective Therapy.

ACS Appl Mater Interfaces 2019 Apr 18. Epub 2019 Apr 18.

Due to the abuse of antibiotics and the threats of antibiotic-resistance, bacterial infection is still one of the most difficult issues to be resolved. Thus, it is of great significance to explore novel antibacterial agents. In this paper, we investigate a type of silica coated gold-silver nanocages (Au-Ag@SiO2 NCs) as antibacterial candidates. Read More

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http://dx.doi.org/10.1021/acsami.9b01149DOI Listing

[Differentiated approach to treatment of decompensated lower limb ischaemia with the use of the WIFI classification system].

Angiol Sosud Khir 2019 ;25(1):9-16

Russian University of Friendship of Peoples, Moscow, Russia.

In the present article, the authors substantiate the necessity of subdividing a heterogeneous cohort of patients presenting with Fontaine-Pokrovsky grade IV critical limb ischaemia into subgroups with the aim of making an appropriate therapeutic decision and predicting the outcome. We also translated into the Russian language the WIfI classification system developed by the Society for Vascular Surgery (2014) in order to predict limb loss and feasibility of performing revascularization. This is followed by comments on the classification, accompanied by examples of own clinical case studies. Read More

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http://dx.doi.org/10.33529/angio2019101DOI Listing
January 2019
1 Read

Multicenter Phase II Study of Intraoperative Radiotherapy of Early Breast Cancer: Ipsilateral Tumor Recurrence.

Ann Surg Oncol 2019 Apr 16. Epub 2019 Apr 16.

Department of Breast Oncology, Aichi Cancer Center Hospital, Nagoya, Japan.

Background: We performed a multicenter phase II study on the efficacy and safety of intraoperative radiotherapy (IORT) as partial breast irradiation using multiple devices.

Methods: The primary endpoint was ipsilateral breast tumor recurrence (IBTR). Key inclusion criteria were T < 2. Read More

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http://dx.doi.org/10.1245/s10434-019-07350-7DOI Listing
April 2019
5 Reads

Operative vaginal delivery and post-partum infection.

Best Pract Res Clin Obstet Gynaecol 2019 Apr 29;56:93-106. Epub 2018 Sep 29.

National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, UK. Electronic address:

During the past decade, there has been an increase in the awareness of infections associated with pregnancy and delivery. The most significant cause of post-partum infection is caesarean section; 20-25% of operations are followed by wound infections, endometritis or urinary tract infections. Approximately 13% of women in the UK undergo operative vaginal delivery (OVD) with forceps or vacuum, which is also associated with an increased risk of infection, estimated at 0. Read More

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http://dx.doi.org/10.1016/j.bpobgyn.2018.09.005DOI Listing
April 2019
2 Reads

Efficacy of Antiseptic Solutions in Treatment of Infected Surgical Wounds with Patches of Vascular Graft: An Experimental Study in Rats.

Medicina (Kaunas) 2019 Apr 15;55(4). Epub 2019 Apr 15.

Vilnius University Faculty of Medicine, Vilnius, LT-03101, Lithuania.

Treatment of a prosthetic vascular graft infection (PVGI) remains a challenging problem in vascular surgery. The aim of this study was to design a novel rat model for treatment of peripheral vascular prosthesis infection caused by and to determine the efficacy of different antiseptic solutions in suppressing or eradicating infection from the wound and the graft material itself. A piece of Dacron vascular prosthesis was surgically implanted at the dorsum of 48 Wistar rats and the wounds were infected with 5 McFarland standard inoculum of . Read More

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http://dx.doi.org/10.3390/medicina55040106DOI Listing

Health-related Quality of Life and Wound Care Practices Among Patients With Chronic Wounds in a Southwestern Nigerian Community.

Wounds 2019 Mar 29. Epub 2019 Mar 29.

Obafemi Awolowo University Teaching Hospitals' Complex, Ile-Ife, Osun State, Nigeria.

Introduction: Chronic wounds (CWs) are a common problem around the world. Although known to affect quality of life, patients' perception may vary among cultures.

Objective: The purpose of this article is to determine the effects of CWs on health-related quality of life (HRQoL) and identify wound care practices among a select population in southwestern Nigeria. Read More

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March 2019
1 Read

Nosocomial infections in surgical intensive care unit: A retrospective single-center study.

Int J Crit Illn Inj Sci 2019 Jan-Mar;9(1):16-20

Department of Anaesthesiology and Critical Care, Smt. Kashibai Navale Medical College, Pune, Maharashtra, India.

Aims: This study aims to study the incidence, microbiological and antibiotic sensitivity and resistance profile and impact on intensive care units (ICUs) stay and mortality of nosocomial infections in patients admitted to surgical ICU of our hospital.

Methods: A retrospective analysis of all patients admitted, over the course of 1 year, in the surgical ICU was undertaken. All patients who developed nosocomial infections were included in the study. Read More

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http://www.ijciis.org/text.asp?2019/9/1/16/253764
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http://dx.doi.org/10.4103/IJCIIS.IJCIIS_57_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423928PMC
April 2019
3 Reads

Aesthetic Comparison between Subcuticular Suture and Staple Closure of Anterior Cervical Decompression and Fusion Incision Scars: A Prospective Controlled Single-blinded Trial.

Cureus 2019 Feb 1;11(2):e3996. Epub 2019 Feb 1.

Neurosurgery, Ascension Providence Hospital Michigan State University College of Human Medicine, Southfield, USA.

Introduction: Anterior cervical decompression and fusion (ACDF) procedures are common and neck scar appearance is important aesthetically. This study compared subcuticular suture closure with staple closure regarding the aesthetics of the neck incision scar.

Methods: A single-blinded comparative prospective study with two cohorts involving one facility and multiple surgeons was done to study all consecutive patients who underwent one/two-level ACDF operations from 2015-2016. Read More

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http://dx.doi.org/10.7759/cureus.3996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445560PMC
February 2019

Efficacy of local wound infiltration analgesia with ropivacaine and dexmedetomidine in tubercular spine surgery - A pilot randomised double-blind controlled trial.

Indian J Anaesth 2019 Mar;63(3):182-187

Department of Orthopaedics, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India.

Background And Aims: Regional analgesic techniques are difficult to use in tubercular spine patients due to distorted spinal anatomy and presence of infection. This study was conducted with the aim to evaluate analgesic efficacy of local wound infiltration before wound closure in tubercular spine patients.

Methods: This pilot randomised double-blind controlled study was conducted in 32 American Society of Anesthesiologists I-III patients, age ≥15 years, undergoing elective surgery for spinal tuberculosis. Read More

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http://dx.doi.org/10.4103/ija.IJA_780_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423940PMC
March 2019
1 Read

Treatment with the glycoside hydrolase PslG combats wound infection by improving antibiotic efficacy and host innate immune activity.

Antimicrob Agents Chemother 2019 Apr 15. Epub 2019 Apr 15.

Department of Microbiology, University of Washington, Seattle, Washington, United States of America

is an opportunistic, nosocomial bacterial pathogen that forms persistent infections due to the formation of protective communities, known as biofilms. Once formed, the bacteria embedded within the biofilm are recalcitrant to antimicrobial treatment and host immune defenses. Moreover, the presence of biofilms in wounds is correlated with chronic infection and delayed healing. Read More

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http://dx.doi.org/10.1128/AAC.00234-19DOI Listing

Care Bundle Approach to Minimizing Infection Rates after Neurosurgical Implants for Neuromodulation: A Single Surgeon Experience.

World Neurosurg 2019 Apr 12. Epub 2019 Apr 12.

Department of Neurosurgery, U.S. Department of Veterans Affairs Medical Center, Milwaukee, WI 53295; Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI 53226.

Introduction: Implant-related infections carry a high morbidity. Infectious rates for neuromodulation implants range from 1-9% for DBS, 0-10% for SCS systems, and 3-15% for IT pump systems. Meanwhile, studies on care bundles report infection rate reduction to 1. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.04.003DOI Listing

High prevalence of extended-spectrum beta-lactamase-producing Gram-negative pathogens from patients attending Felege Hiwot Comprehensive Specialized Hospital, Bahir Dar, Amhara region.

PLoS One 2019 15;14(4):e0215177. Epub 2019 Apr 15.

Department of Medical Microbiology, School of Biomedical and laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Background: Infections caused by extended-spectrum beta-lactamases (ESBL) producing Gram-negative bacteria has emerge as a global threat in clinical practices. The treat is more serious in developing countries due to inappropriate use, poor adherence, use of counterfeit, sub-standard antibiotics and poor infection control practices. Data on ESBL producing Gram-negative bacteria are limited in developing countries including Ethiopia. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215177PLOS
April 2019
3.234 Impact Factor

Contamination Risk During Fecal Management Device Removal: An In vitro, Simulated Clinical Use Study.

Wound Manag Prev 2019 Mar;65(3):30-37

ConvaTec, Deeside, UK.

Fecal management devices (FMDs) are used to drain and contain fecal matter in incontinent, often acutely or critically ill patients to protect their skin as well as the environment from contamination. However, there is potential for contamination and resultant infection at various stages of FMD use.

Purpose: This in vitro study was conducted to compare device removal factors and subsequent splash of simulated fecal matter of 3 different designs of FMDs using a simulated rectum. Read More

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March 2019
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The Polish Prevalence of Infection in Intensive Care (PPIC): A one-day point prevalence multicenter study.

Adv Clin Exp Med 2019 Apr 13. Epub 2019 Apr 13.

Department of Anesthesiology and Intensive Care, Wrocław University Hospital, Poland.

Background: Infections in critically ill patients are the main reasons for a lack of therapeutic success and increased mortality in intensive care units (ICUs). There have been many analyses of the incidence of infections in ICUs; however, no large studies of this kind have been conducted either in Poland or in Eastern and Central Europe.

Objectives: The aim of the research was to undertake a one-day study of the prevalence of infections in ICUs in Warsaw and the Mazovian region of Poland. Read More

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http://dx.doi.org/10.17219/acem/94147DOI Listing
April 2019
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Treatment experience for full-thickness wound dehiscence with cerebrospinal fluid leakage following posterior primary spine surgery: Three case reports.

Medicine (Baltimore) 2019 Apr;98(15):e15126

Department of Orthopedics, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China.

Rationale: Full-thickness wound dehiscence with cerebrospinal fluid (CSF) leakage following posterior spine surgery is a rare but troublesome complication. In the present study, 3 clinical cases associated with this entity are reported.

Patient Concerns: The first case developed incision effusion 5 days after posterior decompression and internal fixation for lumbar spinal stenosis. Read More

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http://dx.doi.org/10.1097/MD.0000000000015126DOI Listing
April 2019
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Temporary External Fixation Can Stabilize Hip Transposition Arthroplasty After Resection of Malignant Periacetabular Bone Tumors.

Clin Orthop Relat Res 2019 Apr 9. Epub 2019 Apr 9.

T. Kunisada, T. Fujiwara, J. Hasei, E. Nakata, T. Ozaki, Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan M. Senda, Department of Rehabilitation, Okayama University Hospital, Okayama, Japan.

Background: The choice of reconstructive procedure to restore limb function is challenging after internal hemipelvectomy. Hip transposition arthroplasty, also known as resection arthroplasty, removes a malignant or aggressive tumor of the pelvis and acetabulum after which the remaining femoral head is moved proximally to the lateral surface side of the sacrum or the underside of the resected ilium after internal hemipelvectomy. It may provide reasonable functional results and have some advantages such as lowering the risk of an infected implant compared with other reconstructions because no foreign implants are used. Read More

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http://dx.doi.org/10.1097/CORR.0000000000000764DOI Listing

Drain Use is Associated with Increased Odds of Blood Transfusion in Total Shoulder Arthroplasty: A Population-Based Study.

Clin Orthop Relat Res 2019 Apr 9. Epub 2019 Apr 9.

J. J. Chan, C. M. Cirino, B. O. Parsons, S. G. Anthony, L. M. Galatz, P. J. Cagle, Leni and Peter W. May Department of Orthopaedics, Icahn School of Medicine at Mount Sinai, New York, NY, USA H.-H. Huang, J. Poeran, Leni and Peter W. May Department of Orthopaedics / Institute for Healthcare Delivery Science, Department of Population Health Science & Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA M. Mazumdar, Institute for Healthcare Delivery Science, Department of Population Health Science & Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Background: In the absence of evidence supporting its benefit, the American Academy of Orthopaedic Surgeons (AAOS) strongly recommends against closed wound drainage in TKA; however, drain usage remains common in other joints, including the shoulder. While an extensive body of research exists for drain use in lower extremity joint arthroplasty, large-scale data on drain use and its association with benefits and complications in shoulder arthroplasties is lacking. Such data may be particularly valuable given the rapidly increasing demand for shoulder arthroplasties. Read More

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http://dx.doi.org/10.1097/CORR.0000000000000728DOI Listing

Risk Factors for Surgical Site Infection in Neonates: A Systematic Review of the Literature and Meta-Analysis.

Front Pediatr 2019 29;7:101. Epub 2019 Mar 29.

Division of General and Thoracic Surgery, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.

Surgical site infections (SSI) contribute to postoperative morbidity and mortality in children. Our aim was to evaluate the prevalence and identify risk factors for SSI in neonates. Using a defined strategy, three investigators searched articles on neonatal SSI published since 2000. Read More

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http://dx.doi.org/10.3389/fped.2019.00101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449628PMC