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Vet Comp Orthop Traumatol 2019 Jan 15;32(1):18-25. Epub 2019 Jan 15.

Virginia Veterinary Surgical Associates, a BluePearl Partner, Richmond, Virginia, United States.

Objective:  The main aim of this study was to evaluate the efficacy of a topical 2-octyl cyanoacrylate (2OC) tissue adhesive and an adhesive barrier dressing (BD) in minimizing the incidence of surgical site infections (SSI) in dogs undergoing a tibial plateau levelling osteotomy (TPLO).

Materials And Methods:  In a prospective clinical study, 437 client-owned dogs undergoing a TPLO as treatment for cranial cruciate ligament disease with or without concurrent patellar luxations from July 2015 to September 2016 were included. In each dog, the type of postoperative wound dressing was randomly selected as either no dressing (ND), a 2OC tissue adhesive or an adhesive BD. Read More

J Periodontol 2018 Dec 5. Epub 2018 Dec 5.

Department of Dental Diagnostic and Surgical Sciences, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba.

Background: The purpose was to compare patient-centered outcomes, early wound healing, and postoperative complications at palatal donor area of subepithelial connective tissue grafts (CTG) between cyanoacrylates tissue adhesives and polytetrafluoroethylene (PTFE) sutures.

Methods: Thirty-six patients who required harvesting of CTG were enrolled in this randomized clinical trial and assigned to one of two groups. In the "suture" group, wound closure was achieved with standardized continuous interlocking 6-0 PTFE sutures, while in the "cyanoacrylate" group, a high viscosity blend of n-butyl and 2-octyl cyanoacrylate was applied until hemostasis was achieved. Read More

Vet Surg 2018 Nov 10;47(8):1087-1093. Epub 2018 Oct 10.

Small Animal Department, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.

Objective: To compare cutaneous wound closure with mesh and 2-octyl cyanoacrylate (MOC) vs an intradermal suture pattern (ISP) in terms of time of application and biomechanical properties.

Sample Population: Experimental study with 12 female beagle dogs.

Methods: A skin incision was created from the xiphoid to the pubis as part of an ovariohysterectomy; the linea alba and subcutaneous tissue were closed routinely. Read More

Injury 2018 Oct 17;49(10):1942-1946. Epub 2018 Aug 17.

Department of Orthopaedic Surgery, Korea University Guro Hospital, 148 Gurodong-ro, Guro-gu, Seoul, 08308, Republic of Korea. Electronic address:

Meticulous skin closure is required to avoid wound problems after Achilles tendon surgery. The purpose of our study was to compare postoperative complication rate, operation time, clinical outcome and patient satisfaction with the wound among two topical skin adhesives (2-octyl cyanoacrylate and n-butyl cyanoacrylate) and conventional nylon skin sutures in Achilles tendon repair surgery. We retrospectively reviewed the records 122 consecutive patients (40 patient in nylon skin suture, 43 patients in 2-octyl cyanoacrylate and 39 patients in n-butyl cyanoacrylate) who underwent surgical repair for acute Achilles tendon rupture between 2012 and 2016. Read More

Plast Reconstr Surg 2018 10;142(4):850-856

New York, N.Y. From New York-Presbyterian Hospital/Columbia University Medical Center.

Background: An ideal wound closure system is one that is effective, consistent, and efficient. Recent studies have demonstrated the efficacy of octyl-2-cyanoacrylate and mesh (Dermabond Prineo) in the closure of surgical wounds. This study compared the use of Prineo to use of subcuticular suture closure in reduction mammaplasty. Read More

Surg Technol Int 2018 06;32:25-31

Lake Erie College of Osteopathic Medicine, Erie, Pennsylvania.

Traditionally, surgical procedures within the realm of both general and gynecological surgery employ the use of staples and interrupted sutures that run continuously with knot tying or subcuticular sutures to ensure closure of large wound incisions, subcuticular incisions, and fascial repair. However, these methods may not always be cosmetically favorable and, thus, result in an unpleasant outcome for the patient, adding to their surgery-related stress. It is, therefore, imperative that surgeons and gynecologists are aware of alternative methods of wound closure that are not only cosmetically favorable, but also ensure rapid wound recovery and infection control. Read More

J Surg Res 2018 06 22;226:166-172. Epub 2018 Feb 22.

Obstetrics, Gynecology, and Women's Health Institute, Cleveland Clinic Foundation, Cleveland, Ohio.

Background: Anastomotic leak after colorectal surgery is a significant cause of morbidity and mortality. The aim of this study was to evaluate the impact of a reinforced colo-colonic anastomosis with tissue adhesive, 2-octylcyanoacrylate (2-OCA), on the integrity of anastomotic healing as measured by anastomotic bursting pressure.

Methods: Sixty-eight female Sprague-Dawley rats underwent a rectosigmoid colon transection and a sutured end-to-end anastomosis followed by randomization to receive no further intervention or reinforcement with the tissue adhesive, 2-OCA. Read More

J Am Vet Med Assoc 2018 Jan;252(2):215-221

CASE DESCRIPTION 5 cats (9 eyes) were evaluated for surgical correction of bilateral eyelid agenesis. CLINICAL FINDINGS All eyes lacked > 25% of the temporal upper eyelid, and all cats had clinical signs attributable to chronic ocular exposure. Abnormalities were limited to the ocular surface in the 4 female cats, whereas the sole male cat had additional abnormalities consistent with anterior segment dysgenesis. Read More

Orthopedics 2018 Mar 22;41(2):e289-e291. Epub 2017 Sep 22.

Two-octyl cyanoacrylate is a popular skin adhesive used for closing surgical incisions. Since Food and Drug Administration approval in 1998, the few reports of adverse reactions following its use have primarily been limited to the nonorthopedic literature. The authors present a case series of contact dermatitis associated with 2-octyl cyanoacrylate following orthopedic surgery and a review of the literature on the diagnosis and treatment of this complication. Read More

J Arthroplasty 2017 12 18;32(12):3742-3747. Epub 2017 Jul 18.

Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.

Background: While studies have shown that postoperative wound complications can predispose to deep infection following orthopedic surgery, the best form of skin closure has not been elucidated. Furthermore, the unique risks and benefits of each type of wound closure have not been studied. The goal of this study is to present the diagnosis and treatment of patients with allergic contact dermatitis (ACD) from 2-octyl cyanoacrylate, a skin adhesive commonly used in wound closure. Read More

Orthopedics 2017 Sep 9;40(5):e784-e787. Epub 2017 Jun 9.

Wound closure in primary knee arthroplasty is important both for surgical success, by minimizing the risk of wound complications and infection, and for patient satisfaction with wound care and cosmesis. This article reports the use of a topical self-adhering, pressure-sensitive polyester mesh combined with 2-octyl cyanoacrylate adhesive for final skin closure of primary knee arthroplasty without external staples or sutures. During a 2. Read More

J Arthroplasty 2017 08 24;32(8):2431-2435. Epub 2017 Feb 24.

Department of Surgery, Western University, London Health Sciences Center, University Hospital, London, Ontario, Canada.

Background: There are various possible methods of skin closure in total hip arthroplasty (THA) through a lateral skin incision. The cost and time required for each can vary between techniques. The objective of this study was to determine whether there is a difference in patient and surgeon rating of scar outcome using a combination of subcuticular suture and skin adhesive (subcuticular MONOCRYL and DERMABOND [SMD]) vs staples for skin closure after THA. Read More

J Mater Sci Mater Med 2017 Apr 16;28(4):58. Epub 2017 Feb 16.

Networking Biomedical Research Centre on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain.

The less traumatic use of surgical adhesives rather than sutures for mesh fixation in hernia repair has started to gain popularity because they induce less host tissue damage and provoke less postoperative pain. This study examines the host tissue response to a new cyanoacrylate (CA) adhesive (n-octyl, OCA). Partial defects (3 × 5 cm) created in the rabbit anterior abdominal wall were repaired by mesh fixation using OCA, Glubran2(n-butyl-CA), Ifabond(n-hexyl-CA) or sutures. Read More

Am J Obstet Gynecol 2017 Apr 30;216(4):406.e1-406.e5. Epub 2017 Jan 30.

Department of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba, Israel; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Background: The optimal choice of skin closure at cesarean delivery has not yet been determined.

Objective: This study compared wound complications and scar healing following cesarean delivery between 2 methods of skin closure: glue (Dermabond; Ethicon, Somerville, NJ) and monofilament (Monocryl; Ethicon) epidermal sutures.

Study Design: We conducted a randomized controlled trial in which pregnant women undergoing a scheduled cesarean delivery were randomly assigned to skin (epidermis) closure with glue or with a monofilament synthetic suture. Read More

Phys Sportsmed 2017 05 25;45(2):195-198. Epub 2017 Jan 25.

a Department of Orthopaedic Surgery , NYU Langone Hospital for Joint Diseases , New York , NY , USA ​.

​We retrospectively reviewed the records of 3 patients (3 knees) with a delayed type hypersensitivity reaction following Dermabond exposure after an orthopaedic knee procedure. Delayed hypersensitivity reactions are mediated by CD4+ helper T cells. The use of skin adhesives in place of traditional sutures is increasing in popularity given Dermabond's potential benefits of decreased wound infection rate and better wound approximation. Read More

Pediatr Emerg Care 2019 Jan;35(1):75-77

Betsi Cadwaladr University Health Board, Emergency Department, Ysbyty Gwynedd, Bangor, Wales, United Kingdom.

Objectives: Nail bed injuries are common in children, with nail bed damage accounting for 15% to 24% of fingertip injuries. Our objective was to see whether medical adhesives, the cyanoacrylates including Histoacryl and Dermabond, could be used to fix nail bed lacerations as opposed to doing a primary repair with sutures, thus potentially being a quicker method for repair in the emergency department for these injuries.

Methods: We conducted a literature review using the search engines MEDLINE, PubMed, Web of Science, and Google Scholar, and the references within these articles were also integrated. Read More

J Vasc Interv Radiol 2017 Jan 9;28(1):111-116. Epub 2016 Nov 9.

Department of Radiology, Division of Vascular and Interventional Radiology, Duke University Medical Center, Box 3808, 2301 Erwin Road, Durham, NC 27710. Electronic address:

Purpose: To compare early outcomes of skin closure with octyl cyanoacrylate skin adhesive versus subcuticular suture closure.

Materials And Methods: Over a 7-month period, 109 subjects (28 men and 81 women; mean age, 58.6 y) scheduled to undergo single-lumen implantable venous port insertion for chemotherapy were randomly assigned to skin closure with either octyl cyanoacrylate skin adhesive or absorbable subcuticular suture after suturing the deep dermal layer. Read More

J Cutan Med Surg 2017 May/Jun;21(3):253-255. Epub 2016 Nov 4.

2 The Philadelphia Hand Center, P.C., Department of Orthopaedic Surgery, Thomas Jefferson University, Philadelphia, PA, USA.

Background: Friction blisters on the hand are challenging to treat as conventional dressings are prone to saturation, contamination, and loosening with active hand use and other mechanical stresses. Alternative methods and materials for dressing hand blisters warrant exploration.

Case Summary: A 48-year-old male surgeon presented with friction blisters over his bilateral thumbs. Read More

Ear Nose Throat J 2016 Oct-Nov;95(10-11):452-453

Department of Otolaryngology, Madigan Army Medical Center, 9040 Jackson Ave., Tacoma, WA 98431, USA.

Laryngeal trauma is a rare occurrence that can result in significant morbidity and mortality. Isolated cricoid cartilage fractures are exceedingly rare, and their treatment is highly variable. We describe a case of an isolated comminuted, uncalcified cricoid cartilage fracture in a 34-year-old man that responded well to novel management with suture and 2-octylcyanoacrylate tissue adhesive fixation intraoperatively and topical ciprofloxacin/dexamethasone applied to the airway postoperatively. Read More

Can J Rural Med 2016 ;21(4):113-6

Centre de santé et de services sociaux du Témiscamingue-et-de-Kipawa, Témiscaming, Que.

Int J Nanomedicine 2016;11:4213-20. Epub 2016 Aug 29.

Collaborative Innovation Center for Nanomaterials & Optoelectronic Devices, College of Physics, Qingdao University; Industrial Research Institute of Nonwovens & Technical Textiles, College of Textiles & Clothing.

Purpose: In this work, we propose an in situ precise electrospinning of medical glue fibers onto dural wound for improving sealing capability, avoiding tissue adhesion, and saving time in dural repair.

Methods: N-octyl-2-cyanoacrylate, a commercial tissue adhesive (medical glue), can be electrospun into ultrathin fibrous film with precise and homogeneous deposition by a gas-assisted electrospinning device.

Results: The self-assembled N-octyl-2-cyanoacrylate film shows high compactness and flexibility owing to its fibrous structure. Read More

Am J Surg 2017 Jan 16;213(1):151-158. Epub 2016 Jun 16.

Department of Surgery, Erasmus University Medical Center, Room Ee-173, Postbus 2040, 3000 CA Rotterdam, The Netherlands.

Background: Tissue adhesives (TAs) in gastrointestinal surgery are gradually gaining acceptance. Before implementation as colonic sealants, an evaluation of the sealing capability of a TA when in contact with fecal matter, as in a leaking anastomosis, is needed. In this study, we used clinically available TAs for the sutureless closure of colonic defects evaluating mechanical strength and tissue healing. Read More

Klin Khir 2016 Apr(4):61-3

Abstract Comparison of postoperative kinds of cicatrix was conducted in 60 patients, depending on the suture material applied. Best conditions for the operative wound healing, achievement of more esthetic normotrophic cicatrix were guaranteed by application of a cutaneous adhesive. Read More

Dermatitis 2016 Mar-Apr;27(2):75-6

Division of Clinical Dermatology Mayo Clinic Rochester, MN Division of Adult Reconstruction Mayo Clinic Rochester, MN.

J Wound Care 2016 Jan;25(1):40, 42-5

Department of Orthopaedics, Glasgow Royal Infirmary, 84 Castle Street, Glasgow, Scotland, G4 0SF.

Objective: This study compared three methods of surgical wound dressing in patients undergoing primary total hip arthroplasty to determine their effect on wound leakage.

Method: Total hip arthroplasties were randomised to 3 groups: 2-octyl cyanoacrylate (Dermabond-Ethicon Inc, G) with Opsite (Smith & Nephew; O) [G+O], 2-octyl cyanoacrylate with Tegaderm (3M; T) [G+T], and Opsite without 2-octyl cyanoacrylate [O]. Postoperative wound leakage was assessed and graded daily until discharge, the frequency of the dressing changes was also recorded. Read More

Can J Urol 2015 Oct;22(5):7995-9

Maine Medical Center, Portland, Maine, USA.

Introduction: Circumcision is the most commonly performed surgical procedures in male children. Maine is one of 18 states in the United States which does not pay for neonatal circumcisions. The aim of this study was to perform outcomes and cost analysis of a sutureless circumcision technique versus circumcision using sutures. Read More

BMC Musculoskelet Disord 2015 May 13;16:116. Epub 2015 May 13.

Center for Advanced Orthopaedic Studies, Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

Background: Hemostatic agents, tissue adhesives and sealants may contribute to a reduction in hemorrhage-associated morbidity and mortality. Towards this end, we have recently developed a lysine-based dendritic hydrogel (PEG-LysNH2) that can potentially be used in the management of severe trauma and/or intraoperative bleeding. As a first step in demonstrating the potential utility of this approach, our objective was to ascertain the ability of the PEG-LysNH2 to adhere to and seal injured tissues, as well as to maintain the seal under physiological conditions. Read More

Case Rep Med 2015 1;2015:642595. Epub 2015 Apr 1.

MUSC Division of Plastic Surgery, 96 Jonathan Lucas Street, CSB 404, MSC 613, Charleston, SC 29425, USA.

Background. Bilateral reduction mammoplasty is a common plastic surgery procedure that can be complicated by unfavorable scar formation along incision sites. Surgical adhesives can be utilized as an alternative or as an adjunct to conventional suture closures to help achieve good wound tension and provide an adequate barrier with excellent cosmesis. Read More

J Pediatr Urol 2015 Jun 20;11(3):147.e1-5. Epub 2015 Mar 20.

AZ St Lucas, Department of Urology, Groenebriel 1, 9000 Ghent, Belgium. Electronic address:

Introduction: Circumcision is the most common surgical procedure in male children in the world and is performed because of cultural, religious or medical reasons. Traditionally, interrupted sutures are used to close the wound, but 2-Octyl cyanoacrylate (2-OCA) tissue glue can be used as an alternative method to close the circumcision wound.

Objectives: To compare the use of 2-OCA with absorbable sutures in circumcision wound closure in prepubescent patients in terms of operative time, complication rate, postoperative pain and cosmetic results. Read More

J Emerg Med 2015 Jun 15;48(6):702-5. Epub 2015 Apr 15.

Department of Emergency Medicine, Kaiser Permanente, San Francisco, California and Emergency Department, University of California San Francisco, San Francisco, California.

Background: Distal fingertip pad dermal avulsion injuries can be challenging for emergency physicians. A common occurrence with these injuries is difficult-to-control bleeding. The nature of these wounds is such that conventional primary closure to achieve hemostasis is not feasible. Read More

Rev Bras Cir Cardiovasc 2015 Jan-Mar;30(1):119-26

Instituto de Infectologia Emílio Ribas, São Paulo, SP, Brazil.

Objective: To evaluate the behavior of castor oil-derived polyurethane as a hemostatic agent and tissue response after abdominal aortic injury and to compare it with 2-octyl-cyanoacrylate.

Methods: Twenty-four Guinea Pigs were randomly divided into three groups of eight animals (I, II, and III). The infrarenal abdominal aorta was dissected, clamped proximally and distally to the vascular puncture site. Read More

Br J Oral Maxillofac Surg 2015 Apr 14;53(4):358-63. Epub 2015 Feb 14.

Department of Regenerative Medicine, Graduate School of Medicine and Pharmaceutical Sciences for Research, University of Toyama, Japan.

The growth of maxillary bone and the development of dentition are often impaired in patients who have had pushback operations for repair of a cleft palate. There has been considerable discussion about the most suitable technique or material used in such repairs to resolve the problem. Hyperdry amniotic membrane, a new preservable material derived from human amnion, has recently been introduced in several procedures. Read More

Dermatol Surg 2015 Feb;41(2):294-6

Department of Dermatology, State University of New York at Stony Brook East Setauket, New York.

Minerva Pediatr 2015 Apr 21;67(2):111-6. Epub 2015 Jan 21.

Pediatric and Congenital Cardiac Surgery Unit, Department of Cardiac Thoracic and Vascular Sciences, University of Padua, Padua, Italy -

Aim: The aim of this paper was to evaluate the safety and cost-effectiveness of "2-octyl-cyanoacrylate" as skin adhesive in congenital heart surgery.

Methods: From April 2010 to December 2011, we collected data from 300 patients who underwent cardiac surgery for congenital heart disease. We divided our population into 3 groups: group-1 (N. Read More

In Vivo 2015 Jan-Feb;29(1):145-8

Unity of Plastic and Reconstructive Surgery, University of Study of Siena, Siena, Italy.

Unlabelled: Cyanoacrylate skin adhesive is increasingly used to ensure and stabilize wound closures. One of the documented favorable effects of these glues is to limit the risk of a surgical site infection by physically isolating the wound.

Patients And Methods: From January 2005 to January 2013, 900 patients requiring surgical treatment in the Structure of Plastic Surgery of the University of Sienna were enrolled for the study and divided in two groups; 450 patients treated with glue versus 450 controls. Read More

J Wound Care 2014 Sep;23(9):456-8, 460

Arthroplasty Fellow; Northwick Park Hospital, Harrow.

Objective: To compare the cosmetic results, complications and patient satisfaction of 2-octyl cyanoacrylate (Dermabond, Ethicon Inc. Somerville, NJ, USA), a liquid bonding agent, with 3-0 nylon sutures (Ethilon, Ethicon Inc) skin closure in two groups of patients undergoing elective knee arthroscopy at 6 weeks.

Method: The retrospective clinical audit recruited patients undergoing knee surgery for the first time between October 2010 and August 2011. Read More

Prehosp Disaster Med 2014 Oct 16;29(5):546-8. Epub 2014 Sep 16.

3Department of Radiology,Brigham and Women's Hospital,Harvard Medical School,Boston,MassachusettsUSA.

Wound closure with 2-octyl cyanoacrylate (Dermabond; Ethicon, Somerville, New Jersey USA) has recently increased in popularity across a wide spectrum of physicians ranging from surgeons to emergency medicine practitioners. Generally, very few complications are associated with Dermabond and are usually related to application techniques. Uncommonly, patients present with allergic reactions to the adhesive compounds; these allergies are often misdiagnosed as cellulitis or another infectious process, and are incorrectly treated. Read More

Insight 2014 ;39(3):11-3

Biomed Res Int 2014 26;2014:526590. Epub 2014 Jun 26.

Department of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, Ein-Kerem, Jerusalem, Israel.

Our objective was to evaluate the effectiveness of adhesive glue in repairing first degree perineal tears. We conducted a noninferiority prospective, randomized, controlled trial comparing adhesive glue with traditional suturing. Each case was evaluated immediately after birth and after the puerperium. Read More

Ann Plast Surg 2015 Jan;74(1):107-10

From the *Mayo Clinic Florida Department of General Surgery, and †Division of Plastic Surgery, Mayo Clinic Florida, Jacksonville, FL.

Introduction: The use of tissue adhesives for the closure of surgical incisions is increasing. Few studies directly compare tissue adhesives to one another or focus on the difference in wound closure time between tissue adhesives. We compared the use of N-butyl-2 cyanoacrylate (Histoacryl), octyl cyanoacrylate (Dermabond), or subcuticular suture in incisions resulting from reduction mammoplasty, mastopexy, panniculectomy, and abdominoplasty. Read More

Nanoscale 2014 Jul;6(14):7792-8

Institute & Hospital of Hepatobiliary Surgery, Key Laboratory of Digital Hepatobiliary Surgery of Chinese PLA, Chinese PLA Medical Academy, Chinese PLA General Hospital, Beijing 100853, P. R. China.

Rapid hemostasis of solitary organs is still a big challenge in surgical procedures or after major trauma in both civilians and on the battlefield. Here, we report the first use of an airflow-directed in situ electrospinning method to precisely and homogeneously deposit a medical glue of n-octyl-2-cyanoacrylate (OCA) ultrathin fibers onto a wound surface to realize rapid hemostasis in dozens of seconds. In vivo and in vitro experiments on pig liver resection demonstrate that the self-assembled electrospun OCA membrane with high strength, good flexibility and integrity is very compact and no fluid seeping is observed even under a pressure of 147 mm Hg. Read More

Dermatitis 2014 Mar-Apr;25(2):99-100

St Joseph Mercy Health System Ypsilanti, MI.

Eur Spine J 2014 Apr 1;23(4):854-62. Epub 2014 Feb 1.

Department of Orthopedic Surgery, Wakayama Rosai Hospital, 93-1 Kinomoto, Wakayama, Wakayama, 640-8505, Japan,

Background: Surgical site infection (SSI) after spinal surgery is a devastating complication. Various methods of skin closure are used in spinal surgery, but the optimal skin-closure method remains unclear. A recent report recommended against the use of metal staples for skin closure in orthopedic surgery. Read More

J Orthop Traumatol 2014 Sep 31;15(3):189-94. Epub 2013 Dec 31.

Metropolitian Orthopedics, Missouri Baptist Medical Center, 3009 Ballas Road, Suite 105 B, St. Louis, MO, 63131, USA.

Background: Recent publications have shown an infection rate of 5-7 % for acetabular fractures treated with the Kocher-Langenbeck (K-L) approach. Using metallic staples to close hip skin incisions has been considered the gold standard. The purpose of this study was to answer the following: (1) will closure of a K-L incision after acetabular fracture surgery with a running subcuticular monocryl suture, then sealing the wound with 2-octyl cyanoacrylate (OCA), result in a lower infection rate compared to metallic staple closure? (2) Do incisions closed with subcuticular monocryl and OCA exhibit decreased drainage? (3) Is there a cost difference between these two methods?

Materials And Methods: In a prospective clinical study, 103 patients with acetabular fractures treated using the K-L approach were randomized into two groups: skin closure with metallic staples (n = 52) versus subcuticular running monocryl suture sealed with OCA (n = 51). Read More

J Oral Maxillofac Surg 2013 Dec;71(12):2152.e1-8

Lecturer, Department of Oral and Maxillofacial Surgery, Himachal Pradesh Government Dental College and Hospital, Shimla, Himachal Pradesh, India. Electronic address:

Purpose: To compare octyl-2-cyanoacrylate (2-OCA) tissue adhesive with subcuticular suture for the closure of incisions in the maxillofacial region to determine 1) whether it is faster than traditional subcuticular suturing, 2) whether the number and length of incisions affect closure time, 3) wound morbidity, 4) patient satisfaction outcome, and 5) cosmetic outcome.

Material And Methods: In a prospective randomized clinical trial, 29 patients were allocated to 1 of 2 groups for the closure of skin incisions using 2-OCA or conventional subcuticular skin sutures. Postoperative follow-up evaluated wound healing at 5 to 10 days and at 3 months. Read More

J Minim Invasive Gynecol 2014 Mar-Apr;21(2):252-8. Epub 2013 Oct 12.

Department of Obstetrics and Gynecology, Royal Surrey County Hospital NHS Foundation Trust Guildford, Surrey, UK. Electronic address:

Study Objective: To compare LiquiBand Surgical S (LB) (Advanced Medical Solutions Ltd, Plymouth, UK) with High Viscosity Dermabond (DB) (Ethicon Inc., Kirkland, Scotland) for the closure of laparoscopic wounds.

Design: Prospective, multicenter, randomized, controlled trial (Canadian Task Force classification I). Read More

J Drugs Dermatol 2013 Jul;12(7):810-4

Beverly Hospital Oncology Care Center, Beverly, MA, USA.

Background: The use of medical adhesives for topical wound closure is gaining in popularity over conventional wound closure materials such as sutures and staples. Adhesives provide advantages in both wound closure and patient management with good cosmetic outcome and surgeon and patient satisfaction reported.

Objective: To compare the use of two currently marketed medical adhesives; LiquiBand® Flow Control and High Viscosity Dermabond ™ for the topical closure of surgical incisions. Read More

J Craniofac Surg 2013 Jul;24(4):1314-6

Department of Plastic Surgery, University of Virginia Health System, Charlottesville, VA 22908, USA.

Cerebrospinal fluid (CSF) fistulae are problematic because of the high risk of meningitis and other infectious complications, as well as the potential for critically delaying chemotherapy in cases associated with malignancy. The plastic surgical literature suggests vascularized autologous tissue for the treatment of chronically draining CSF fistulae. Many of these patients, however, are debilitated, have multiple comorbidities, and may have a limited life expectancy, making the lengthy surgery and the associated donor-site morbidity of a regional or free tissue transfer procedure unattractive. Read More

J Emerg Med 2013 Dec 1;45(6):846-8. Epub 2013 Jul 1.

Department of Emergency Medicine, State University of New York-Downstate/Kings County Hospital, Brooklyn, New York.

Background: Tongue lacerations provide a challenge for emergency physicians, especially in the case of pediatric patients. Traditional wound closure typically involves local anesthesia or procedural sedation in children, which is time consuming and often anxiety provoking for providers, patients, and parents. 2-Octyl cyanoacrylate (Dermabond(®); Ethicon, Inc. Read More