J Coll Physicians Surg Pak 2017 Sep;27(9):S89-S91
Department of Pathology, Dow International Medical College, Dow University of Health Sciences, Ojha Campus, Karachi.
Langerhans cell histiocytosis (LCH) is the latest terminology for a disorder of reticulo-endothelial system, previously known as histiocytosis X, and marked by aberrant proliferation of bone marrow derived Langerhans cells with variable inflammatory infiltrate including neutrophils, lymphocytes, plasma cells, eosinophils, and multinucleated giant cells. Although rare, the disorder frequently inflicts children with peak incidence recorded in 2-4 years age group. LCH is rare in adults. Read More