Dev Neurobiol 2021 May 3. Epub 2021 May 3.
Department of Biomedical Engineering Sciences, School of Medicine, Loma Linda University, Loma Linda, CA, USA.
Oxidative stress (OS) is one of the most significant propagators of systemic damage with implications for widespread pathologies such as vascular disease, accelerated aging, degenerative disease, inflammation, and traumatic injury. OS can be induced by numerous factors such as environmental conditions, lifestyle choices, disease states, and genetic susceptibility. It is tied to the accumulation of free radicals, mitochondrial dysfunction, and insufficient antioxidant protection, which leads to cell aging and tissue degeneration over time. Read More