578 results match your criteria Wells Syndrome Eosinophilic Cellulitis


Mepolizumab Therapy for Recalcitrant Eosinophilic Annular Erythema in an Adult: A Case Report and Review of Treatment Options.

Dermatol Ther (Heidelb) 2020 Jun 23. Epub 2020 Jun 23.

Department of Dermatology, University of Rzeszow, Rzeszow, Poland.

Eosinophilic annular erythema (EAE) is a rare condition with a chronic relapsing and remitting course, characterized by the presence of annular or polycyclic erythematous and plaque lesions and prominent tissue eosinophilia on histopathology. There is an ongoing discussion on whether EAE is a subset of Wells syndrome (eosinophilic cellulitis) or a separate entity. To date, few cases of EAE have been reported in the literature; of these, about 40 cases were in adults and fewer than ten cases were in children. Read More

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http://dx.doi.org/10.1007/s13555-020-00412-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308446PMC

Eosinophilic Dermatoses: Recognition and Management.

Am J Clin Dermatol 2020 May 11. Epub 2020 May 11.

Dermatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Eosinophilic dermatoses encompass a broad spectrum of diseases of different etiologies hallmarked by eosinophilic infiltration of the skin and/or mucous membranes, with or without associated blood eosinophilia. The wide range of dermatological manifestations of this spectrum, including nodules and plaques, pustules, blisters, ulcers, and urticarial lesions, is reflected in a non-univocal classification system. We identified six groups of eosinophilic dermatoses based on the predominant anatomic level of involvement: (1) epidermal; (2) of the dermal-epidermal junction; (3) dermal; (4) of the hypodermis and muscle fascia; (5) of the pilosebaceous unit; and (6) vascular/perivascular. Read More

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http://dx.doi.org/10.1007/s40257-020-00520-4DOI Listing

Mutation in the Gene in an Egyptian Patient with H Syndrome: A Case Report and Review of Literature.

J Pediatr Genet 2020 Jun 30;9(2):109-113. Epub 2019 Sep 30.

Department of Pediatrics, Faculty of Medicine, Cairo University, Cairo, Egypt.

Histiocytosis-lymphadenopathy plus syndrome (H syndrome) is caused by mutations in the gene that result in histiocytic infiltration of numerous organs. Patients suffering from this disorder can be easily mistaken for similar conditions such as Muckle-Wells syndrome. We present a 9. Read More

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http://dx.doi.org/10.1055/s-0039-1697900DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183402PMC

Wells' syndrome related to Mycoplasma pneumoniae in a 5-year-old boy.

Pediatr Int 2020 May 17;62(5):635-637. Epub 2020 Apr 17.

Department of Pediatrics, Medical Research Institute, Pusan National University School of Medicine, Pusan National University Hospital, Busan, Korea.

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http://dx.doi.org/10.1111/ped.14136DOI Listing

Off-Label studies on anakinra in dermatology: a review.

J Dermatolog Treat 2020 Apr 22:1-14. Epub 2020 Apr 22.

Department of Dermatology and Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Anakinra (Kineret) is an interleukin-1 receptor antagonist (IL-1Ra) FDA approved for use in rheumatoid arthritis and in neonatal-onset multisystem inflammatory disease (NOMID). It has been used off-label for a variety of dermatologic conditions. A review of the available studies and cases of these off-label uses would be valuable to the dermatologist considering alternative treatments for these oftentimes poorly studied conditions. Read More

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http://dx.doi.org/10.1080/09546634.2020.1755417DOI Listing

Muckle-Wells syndrome: manifestations and diagnosis in four generations of a Portuguese family.

World J Pediatr 2020 Apr 3. Epub 2020 Apr 3.

Rheumatology Department, Unidade Local de Saúde Do Alto Minho, Hospital Conde Bertiandos, 4990-041, Ponte de Lima, Portugal.

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http://dx.doi.org/10.1007/s12519-020-00358-0DOI Listing

[Wells syndrome misdiagnosed as bacterial cellulitis].

Rev Med Interne 2020 Feb 20. Epub 2020 Feb 20.

Service de dermatologie et vénéréologie, CHU de Ibn Rochd, Casablanca, Maroc.

Wells syndrome (WS), also called eosinophilic cellulitis is a rare inflammatory skin disease with about 200 cases reports in the literature. It is part of eosinophilic dermatoses and presents a diagnostic challenge. We report a case of WS presenting as bacterial cellulitis. Read More

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http://dx.doi.org/10.1016/j.revmed.2020.02.007DOI Listing
February 2020

Wells syndrome (eosinophilic cellulitis) following vaccination: Two pediatric cases with positive patch test to aluminium salts.

Contact Dermatitis 2020 Jun 20;82(6):401-402. Epub 2020 Feb 20.

Division of dermatology, CHU de Québec, Laval University, Québec, Canada.

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http://dx.doi.org/10.1111/cod.13485DOI Listing

Erysipelas-like presentation of Wells' syndrome (eosinophilic cellulitis).

Reumatismo 2020 Jan 28;71(4):226-229. Epub 2020 Jan 28.

Department of Internal Medicine, Groupe Hospitalier Sud Ile de France, Melun.

Wells' syndrome, also called eosinophilic cellulitis, is a rare eosinophilic dermatosis characterized by an unspecific inflammatory erythematous eruption often associated with systemic symptoms. Here we report the case of a 57-year-old female with bilateral painful pitting and pruritic feet progressive for two weeks despite one week of oral antibiotics. Skin biopsy was performed showing dermal eosinophilic infiltration. Read More

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http://dx.doi.org/10.4081/reumatismo.2019.1252DOI Listing
January 2020

Wells syndrome after radiation therapy.

J Dermatol 2020 Mar 21;47(3):e75-e77. Epub 2020 Jan 21.

Department of Dermatology, Fukushima Medical University, Fukushima, Japan.

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http://dx.doi.org/10.1111/1346-8138.15217DOI Listing

[SYSTEMIC REVIEW OF EOSINOPHILIC DERMATOSES PATIENTS TREATED WITH TNF-Α INHIBITORS AND USTEKINUMAB].

Harefuah 2020 Jan;159(1):34-37

Department of Dermatology, Emek Medical Center, Afula, Israel.

Aims: This study aims to critically review the pros and cons of biological drugs as treatments and triggers of eosinophilic dermatoses.

Background: Eosinophilic dermatoses syndromes are rare diseases with a prominent eosinophilic infiltration mechanism. These syndromes have several known treatments with limited success. Read More

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January 2020

Erratum: Muckle-Wells syndrome in an Indian family associated with NLRP3 mutation.

Authors:

J Postgrad Med 2020 Jan-Mar;66(1):59

[This corrects the article DOI: 10.4103/0022-3859.153107]. Read More

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http://dx.doi.org/10.4103/0022-3859.169506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970326PMC
January 2020

The color of skin: green diseases of the skin, nails, and mucosa.

Clin Dermatol 2019 Sep - Oct;37(5):516-519. Epub 2019 Jul 17.

Medical College, Kolkata, West Bengal, India.

Greenish staining of human skin may result from a gamut of causes, such as chlorosis, exogenous copper, resolving ecchymosis, drugs, green textile dyes, green tattoos, apocrine and eccrine chromhidrosis, hyper biliverdinemia, chloromas, use of green dyes during tube feeding in patient with multiorgan failure, Pseudomonas infections, and Wells' syndrome in its second stage. Physicians may rarely encounter patients with green skin, hair, nails, or mucosae. Read More

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http://dx.doi.org/10.1016/j.clindermatol.2019.07.012DOI Listing
June 2020
2.470 Impact Factor

The NLRP3 inflammasome: a new player in neurological diseases.

Turk J Biol 2019 13;43(6):349-359. Epub 2019 Dec 13.

Department of Molecular Biology and Genetics, Apoptosis and Cancer Immunology Laboratory (AKIL), Boğaziçi University, İstanbul Turkey.

Inflammasomes are supramolecular protein complexes implicated in the detection of pathogens or danger-associated molecules and are responsible for mounting the first line of innate immune response to counteract these signals and restore tissue homeostasis. Among different inflammasomes identified so far, NLRP3 is of main interest since mutations in Nlrp3 gene are associated with autoinflammatory diseases such as Muckle-Wells syndrome, neonatal onset multisystem inflammatory disease, and familial cold urticaria/autoinflammatory syndrome. On the other hand, whereas other inflammasomes are mainly detectors of specific molecular motifs, NLRP3 is acting as a general sensor of cellular perturbations including potassium efflux, lysosomal damage, and ROS production. Read More

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http://dx.doi.org/10.3906/biy-1909-31DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911260PMC
December 2019
1.343 Impact Factor

Cryopyrin-associated periodic fever syndrome in children: A case-based review.

Int J Rheum Dis 2020 Feb 19;23(2):262-270. Epub 2019 Dec 19.

Division of Rheumatology, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.

Cryopyrin-associated periodic fever syndrome (CAPS) represents an increasingly recognized disease group entity, with varied presentations. CAPS includes 3 clinical entities, namely, familial cold-induced autoinflammatory syndrome (FCAS; MIM #120100), Muckle-Wells syndrome (MWS; MIM #191900) and chronic inflammatory neurologic cutaneous and articular syndrome (CINCA; MIM #607115); which share several overlapping clinical features. These patients often present with early-onset episodes of fever and rash, and variable systemic signs and symptoms, making it a great mimicker of other systemic autoimmune diseases. Read More

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http://dx.doi.org/10.1111/1756-185X.13772DOI Listing
February 2020

Wells Syndrome - An Odyssey.

Open Access Maced J Med Sci 2019 Sep 30;7(18):3002-3005. Epub 2019 Jun 30.

Department of Dermatology and Allergology, Städtisches Klinikum Dresden, Academic Teaching Hospital, Dresden, Germany.

Background: Wells syndrome is a rare idiopathic dermatosis of the eosinophilic spectrum. Diagnostic criteria include cutaneous eruptions of variable morphology with eosinophilic infiltrates, peripheral blood eosinophilia, a relapsing, remitting course, and exclusion of systemic disease. Diagnosis is often delayed. Read More

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http://dx.doi.org/10.3889/oamjms.2019.572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910816PMC
September 2019

The Long-Term Efficacy of Cochlear Implantation for Hearing Loss in Muckel-Wells Syndrome.

J Int Adv Otol 2019 Dec;15(3):454-458

Department of Otolaryngology, Gifu University, Gifu, Japan.

Muckle-Wells syndrome (MWS), a subclass of cryopyrin-associated periodic syndrome (CAPS), sometimes includes complications of bilateral progressive sensorineural hearing loss. A 48-year-old woman had been diagnosed with pediatric rheumatic arthritis at aged 6 years; however, systematic therapy with prednisolone and methotrexate showed limited efficacy for her general fatigue and arthritic pain, and it never improved the hearing level. She underwent a cochlear implant surgery for progressive profound bilateral hearing loss. Read More

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http://dx.doi.org/10.5152/iao.2019.6871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937186PMC
December 2019

The NLRP3 p.A441V Mutation in -AID Pathogenesis: Functional Consequences, Phenotype-Genotype Correlations and Evidence for a Recurrent Mutational Event.

ACR Open Rheumatol 2019 Jun 6;1(4):267-276. Epub 2019 Jun 6.

Sorbonne Université INSERM, Hôpital Trousseau Paris France.

Objective: To determine the molecular and cellular bases of autoinflammatory syndromes in a multigenerational French family with Muckle-Wells syndrome and in a patient originating from Portugal with familial cold autoinflammatory syndrome.

Methods: Sequencing of exon 3 was performed in all accessible patients. Microsatellite and whole-genome single nucleotide polymorphism genotyping was used i) to test the intrafamilial segregation of the identified variant and ii) to look for a founder effect. Read More

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http://dx.doi.org/10.1002/acr2.1039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857991PMC

Recognising and understanding cryopyrin-associated periodic syndrome in adults.

Br J Nurs 2019 Oct;28(18):1180-1186

Honorary Research Associate, National Amyloidosis Centre, Division of Medicine, University College London.

Cryopyrin-associated periodic syndrome (CAPS) is a group of rare hereditary autoinflammatory diseases characterised by recurrent flares of mild to severe systemic inflammation and fever. CAPS is the umbrella term for a spectrum of individual conditions, namely familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS) and neonatal-onset multisystem inflammatory disease (NOMID), also known as chronic infantile neurologic, cutaneous and articular (CINCA) syndrome. The flare symptoms include fever, fatigue, rashes, headaches, arthralgia and myalgia that can last for a few hours or for several days. Read More

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http://dx.doi.org/10.12968/bjon.2019.28.18.1180DOI Listing
October 2019
1 Read

Eosinophilic dermatoses.

J Dtsch Dermatol Ges 2019 10 27;17(10):1039-1051. Epub 2019 Sep 27.

Department of Dermatology, University Hospital, Jena, Germany.

Eosinophilic dermatoses are a heterogeneous group of diseases, characterized by an eosinophil-rich infiltrate and/or degranulation of eosinophils. Blood eosinophilia may be an associated feature. Typical, albeit not specific histological findings include 'flame figures', which are caused by the accumulation of cationic proteins released by eosinophils and subsequent collagen denaturation. Read More

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http://dx.doi.org/10.1111/ddg.13943DOI Listing
October 2019
2 Reads

Long-term Remission of Wells Syndrome With Omalizumab.

J Investig Allergol Clin Immunol 2020;30(1):58-59. Epub 2019 Sep 18.

Division of Immunology and Allergology, Department of Internal Medicine, University Hospital and Medical Faculty, Geneva, Switzerland.

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http://dx.doi.org/10.18176/jiaci.0436DOI Listing
September 2019
2 Reads

Wells' syndrome associated with Trichophyton infection.

J Dermatol 2019 Dec 9;46(12):e451-e452. Epub 2019 Sep 9.

Department of Dermatology, Gifu University Graduate School of Medicine, Gifu, Japan.

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http://dx.doi.org/10.1111/1346-8138.15085DOI Listing
December 2019

Well Leg Compartment Syndrome After Prolonged Pelvic Surgery: Launch of United Kingdom and Ireland Multidisciplinary Clinical Guidelines.

Dis Colon Rectum 2019 10;62(10):1150-1152

Department of Colorectal and Intestinal Failure Surgery, Salford Royal National Health Service Foundation Trust, University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.1097/DCR.0000000000001463DOI Listing
October 2019
3 Reads

Erythema Nodosum, Early Stage-A Subcutaneous Variant of Leukocytoclastic Vasculitis? Clinicopathological Correlation in a Series of 13 Patients.

Am J Dermatopathol 2020 May;42(5):329-336

Clinical Department of Dermatology and Venereology, Medical University Innsbruck, Innsbruck, Austria.

Erythema nodosum (EN) is considered to represent a septal panniculitis. In a period from January 2000 until June 2018, we clinically and histopathologically investigated 124 patients with EN, 13 (10.5%) of them in an early stage demonstrating features of a leukocytoclastic vasculitis (LCV) around postcapillary venules of the subcutaneous fat. Read More

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http://dx.doi.org/10.1097/DAD.0000000000001469DOI Listing
May 2020
4 Reads

Recurrent pruritic multifocal erythematous rash.

Cutis 2019 Jun;103(6):E25-E27

Riddle Memorial Hospital, Media, Pennsylvania, USA.

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June 2019
1 Read

Insect bites as a trigger factor of eosinophilic cellulitis.

Ann Agric Environ Med 2019 Jun 30;26(2):256-259. Epub 2018 Oct 30.

Faculty of Medicine, Jan Kochanowski University, Kielce, Poland.

Introduction: The study presents the case report of a Wells Syndrome in a 18-year -ld female. Wells Syndrome is a rare inflammatory skin disorder which seems to present an abnormal eosinophilic response to a number of triggers.

Objective: The aim of the study is to discuss several problems related to the diagnosis and treatment of Wells Syndrome. Read More

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http://dx.doi.org/10.26444/aaem/97367DOI Listing
June 2019
13 Reads

Rapid and Sustained Long-Term Efficacy and Safety of Canakinumab in Patients With Cryopyrin-Associated Periodic Syndrome Ages Five Years and Younger.

Arthritis Rheumatol 2019 11 9;71(11):1955-1963. Epub 2019 Sep 9.

University of Toronto and the Hospital for Sick Children, Toronto, Ontario, Canada.

Objective: To assess long-term efficacy and safety of canakinumab and the response to vaccination in children ages ≤5 years with cryopyrin-associated periodic syndrome (CAPS).

Methods: CAPS patients (ages ≤5 years) received 2 mg/kg canakinumab subcutaneously every 8 weeks; patients with neonatal-onset multisystem inflammatory disease (NOMID) received a starting dose of 4 mg/kg in this open-label trial. Efficacy was evaluated using physician global assessment of disease activity and serum levels of C-reactive protein (CRP) and amyloid A (SAA). Read More

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http://dx.doi.org/10.1002/art.41004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899890PMC
November 2019
11 Reads

Wells syndrome and chronic spontaneous urticaria: report of four cases successfully treated with omalizumab.

J Eur Acad Dermatol Venereol 2019 10 3;33(10):e388-e391. Epub 2019 Jun 3.

Department of Dermatology, Hospital del Mar, IMIM, Universitat Autònoma, Barcelona, Spain.

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http://dx.doi.org/10.1111/jdv.15683DOI Listing
October 2019
3 Reads

CAPS and NLRP3.

J Clin Immunol 2019 04 10;39(3):277-286. Epub 2019 May 10.

Division of Pediatric Allergy, Immunology, and Rheumatology, Rady Children's Hospital of San Diego, University of California, San Diego, San Diego, CA, USA.

Cryopyrin-associated periodic syndrome (CAPS) is a rare inherited autoinflammatory disorder characterized by systemic, cutaneous, musculoskeletal, and central nervous system inflammation. Gain-of-function mutations in NLRP3 in CAPS patients lead to activation of the cryopyrin inflammasome, resulting in the inappropriate release of inflammatory cytokines including IL-1β and CAPS-related inflammatory symptoms. Several mechanisms have been identified that are important for the normal regulation of the cryopyrin inflammasome in order to prevent uncontrolled inflammation. Read More

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http://dx.doi.org/10.1007/s10875-019-00638-zDOI Listing
April 2019
6 Reads

Muckle-Wells Syndrome Across Four Generations in One Czech Family: Natural Course of the Disease.

Front Immunol 2019 16;10:802. Epub 2019 Apr 16.

Paediatric Rheumatology and Autoinflammatory Diseases Unit, Department of Paediatrics and Adolescent Medicine, First Faculty of Medicine, General University Hospital in Prague, Charles University, Prague, Czechia.

Muckle-Wells syndrome (MWS) represents a moderate phenotype of cryopyrinopathies. Sensorineural hearing loss and AA amyloidosis belong to the most severe manifestations of uncontrolled disease. Simultaneous discovery of MWS in four generations of one large kindred has enabled us to document natural evolution of untreated disease and their response to targeted therapy. Read More

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http://dx.doi.org/10.3389/fimmu.2019.00802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477140PMC
April 2019
9 Reads

Spectrum of the neurologic manifestations in childhood-onset cryopyrin-associated periodic syndrome.

Eur J Paediatr Neurol 2019 May 28;23(3):466-472. Epub 2019 Mar 28.

Department of Pediatric Neurology, Istanbul University-Cerrahpasa, Cerrahpasa Medical School, Istanbul, Turkey.

Objective: Neurologic complications of chronic infantile neurologic, cutaneous and articular syndrome (CINCA) are well-known, whereas there are scarce data regarding neurologic features of milder cryopyrin-associated periodic syndrome (CAPS) phenotypes. We aimed to review the neurologic features in detail and summarize the other CAPS-related manifestations in 12 children.

Methods: All children with CAPS that have been followed-up from pediatric rheumatology outpatient clinic, were enrolled to the study. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10903798183056
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http://dx.doi.org/10.1016/j.ejpn.2019.03.006DOI Listing
May 2019
26 Reads

State of care for patients with systemic autoinflammatory diseases - Results of a tertiary care survey.

World Allergy Organ J 2019 14;12(3):100019. Epub 2019 Mar 14.

Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Germany.

Background: Systemic autoinflammatory diseases (SAIDs) are rare debilitating disorders of which there is limited awareness and a significant delay in diagnosis. There is no uniform approach in the diagnosis and treatment of these disorders and the real life state of SAID patient care is poorly characterized. The aim of this study was to obtain data on the epidemiology, state of care and the perception of physicians who are involved in the care of SAID patients. Read More

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http://dx.doi.org/10.1016/j.waojou.2019.100019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439415PMC
March 2019
28 Reads

Vesicles and Bullae on the Right Cheek, Neck, and Both Hands.

JAMA Dermatol 2019 May;155(5):617-618

Department of Dermatology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.

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http://dx.doi.org/10.1001/jamadermatol.2018.5471DOI Listing
May 2019
1 Read

Ankyloblepharon-ectodermal dysplasia-clefting syndrome misdiagnosed as epidermolysis bullosa and congenital ichthyosiform erythroderma: Case report and review of published work.

J Dermatol 2019 May 27;46(5):422-425. Epub 2019 Feb 27.

Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

A Chinese female infant presented with ectodermal dysplasia, cleft palate and severe skin erosions at birth. Although all the typical clinical features of ankyloblepharon-ectodermal dysplasia-clefting (AEC) syndrome were present, the ankyloblepharon was not very marked. We misdiagnosed epidermolysis bullosa and congenital ichthyosiform erythroderma at first and confirmed the diagnosis of AEC syndrome only when she presented with the typical clinical manifestation of recurrent infected scalp erosions at 1 year of age. Read More

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http://dx.doi.org/10.1111/1346-8138.14837DOI Listing
May 2019
9 Reads

Diagnostic utility of a targeted next-generation sequencing gene panel in the clinical suspicion of systemic autoinflammatory diseases: a multi-center study.

Rheumatol Int 2019 05 19;39(5):911-919. Epub 2019 Feb 19.

Department of Molecular Biology-Genetics and Biotechnology, Dr. Orhan Öcalgiray Molecular Biology-Biotechnology and Genetics Research Centre, Graduate School of Science, Engineering and Technology, İstanbul Technical University, Ayazağa Campus, Maslak, 34469, Istanbul, Turkey.

Systemic autoinflammatory diseases (sAIDs) are a heterogeneous group of disorders, having monogenic inherited forms with overlapping clinical manifestations. More than half of patients do not carry any pathogenic variant in formerly associated disease genes. Here, we report a cross-sectional study on targeted Next-Generation Sequencing (NGS) screening in patients with suspected sAIDs to determine the diagnostic utility of genetic screening. Read More

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http://dx.doi.org/10.1007/s00296-019-04252-5DOI Listing
May 2019
16 Reads

Wells' Syndrome Induced by Ustekinumab.

Isr Med Assoc J 2019 Jan;21(1):65

Department of Dermatology, Emek Medical Center, Afula, Israel.

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January 2019
8 Reads

Ocular Involvement in Muckle-Wells Syndrome.

Ocul Immunol Inflamm 2020 17;28(1):70-78. Epub 2018 Dec 17.

Pediatric Allergy and Clinical Immunology, Uludag University School of Medicine, Bursa, Turkey.

: To present the ocular findings of the members of a family that has the diagnosis of Muckle Wells syndrome, a form of cryopyrin associated periodic syndrome (CAPS).: Nine patients with MWS were included in this study. Each study participant underwent a systemic evaluation, comprehensive ophthalmic examination, and auxillary testings. Read More

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https://www.tandfonline.com/doi/full/10.1080/09273948.2018.1
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http://dx.doi.org/10.1080/09273948.2018.1552305DOI Listing
December 2018
39 Reads

Canine Acute Eosinophilic Dermatitis with Edema (Wells-Like Syndrome).

Vet Clin North Am Small Anim Pract 2019 Jan;49(1):47-51

Department of Pathobiology, University of Pennsylvania, School of Veterinary Medicine, 3900 Delancey Street, Philadelphia, PA 19104-6051, USA. Electronic address:

Canine acute eosinophilic dermatitis with edema is an uncommon syndromic disorder in dogs with a unique clinical presentation. Most but not all dogs have a history of gastrointestinal upset preceding or concomitant with skin lesion onset. Affected dogs present with macular to generalized erythema that is most evident on the glabrous skin of the abdomen. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01955616183009
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http://dx.doi.org/10.1016/j.cvsm.2018.08.005DOI Listing
January 2019
53 Reads

Prolonged Treatment of Eosinophilic Erythema Annulare with Chloroquine.

Acta Dermatovenerol Croat 2018 Oct;26(3):262-263

Assoc. Prof. Suzana Ljubojević Hadžavdić, MD, PhD, Department of Dermatology and Venereology University Hospital Center Zagreb School of Medicine University of Zagreb, Šalata 4, 10000 Zagreb, Croatia;

Dear Editor,Eosinophilic annular erythema (EAE) is a rare figurate dermatitis of unknown etiology with prominent tissue eosinophilia. A 59-year-old male patient presented with a one-month history of itchy, polycyclic, annular, and partially serpiginous lesions involving the back, the gluteal region, and the extremities (Figure 1, a, b). There was no medical history of drug intake. Read More

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October 2018
82 Reads

Is chemotherapy the best option for chronic lymphocytic leukemia associated Wells' syndrome? Reply to "Case of Wells' syndrome: A rare association with the clinical course of chronic lymphocytic leukemia".

J Dermatol 2019 04 26;46(4):e146-e147. Epub 2018 Oct 26.

Division of Dermatology, Department of Surgery and Translational Medicine, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1111/1346-8138.14668DOI Listing
April 2019
7 Reads

Early canakinumab therapy for the sensorineural deafness in a family with Muckle-Wells syndrome due to a novel mutation of NLRP3 gene.

Clin Rheumatol 2019 Mar 18;38(3):943-948. Epub 2018 Oct 18.

Department of Pediatrics, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube, Yamaguchi, 755-8505, Japan.

Cryopyrin-associated periodic syndrome (CAPS) is one of the autoinflammatory disorders caused by mutations in NLRP3 gene. The over-production of interleukin (IL)-1β induced by NLRP3 gene mutations plays an important role in the pathophysiology of CAPS. We diagnosed 3 patients with CAPS, who were lineal family members having a novel mutation of NLRP3 gene. Read More

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http://link.springer.com/10.1007/s10067-018-4331-8
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http://dx.doi.org/10.1007/s10067-018-4331-8DOI Listing
March 2019
48 Reads
1.774 Impact Factor

Wells' syndrome associated with eosinophilic panniculitis presenting with multiple subcutaneous nodules.

Eur J Dermatol 2018 Oct;28(5):700-701

Department of Dermatology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.

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http://dx.doi.org/10.1684/ejd.2018.3379DOI Listing
October 2018
13 Reads

[Renal amyloidosis revealing a cryopyrin associated periodic syndrome].

Ann Pathol 2018 Dec 17;38(6):401-406. Epub 2018 Sep 17.

Service d'anatomie et cytologie pathologiques, CHU de Pontchaillou, 2, rue Henri-le-Guilloux, 35033 Rennes cedex 9, France.

Introduction: Cryopyrin associated periodic syndrome is a rare auto inflammatory disease including three clinical entities with a common genetic cause. Among these three entities, Muckle-Wells syndrome is described as an intermediate phenotype associated with a progressive sensorineural hearing loss and AA amyloidosis. The present case reports a renal AA amyloidosis associated with an IgA nephropathy, revealing a Muckle-Wells syndrome. Read More

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http://dx.doi.org/10.1016/j.annpat.2018.07.001DOI Listing
December 2018
22 Reads

A Case of Muckle-Wells Syndrome due to novel NLRP3 mutation.

J Dtsch Dermatol Ges 2018 Oct 29;16(10):1250-1252. Epub 2018 Aug 29.

Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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http://doi.wiley.com/10.1111/ddg.13640
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http://dx.doi.org/10.1111/ddg.13640DOI Listing
October 2018
21 Reads

Red-brown plaque on the leg.

Cutis 2018 Jun;101(6):400;405;406

Department of Dermatology, Oregon Health and Science University, Portland, USA.

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June 2018
10 Reads

Case of Wells' syndrome: A rare association with the clinical course of chronic lymphocytic leukemia.

J Dermatol 2019 Feb 31;46(2):e57-e59. Epub 2018 Jul 31.

Department of Dermatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

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http://dx.doi.org/10.1111/1346-8138.14579DOI Listing
February 2019
28 Reads

Wells syndrome in a patient receiving adalimumab biosimilar: A case report and review of literature.

Indian J Dermatol Venereol Leprol 2018 Sep-Oct;84(5):594-599

Department of Pathology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

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http://dx.doi.org/10.4103/ijdvl.IJDVL_636_17DOI Listing
August 2019
12 Reads