64 results match your criteria Warts Nongenital


Evaluation of intralesional Candida antigen in diabetic patients with multiple warts.

J Cosmet Dermatol 2021 Apr 24;20(4):1248-1253. Epub 2020 Sep 24.

Physiology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

Background: Treatment of warts in diabetic patients with ablative modalities poses a significant risk owing to increased possibility of secondary infection, slow healing, and recurrence. Intralesional immunotherapy has gained popularity in the treatment of warts due to its proven efficacy and good tolerability compared with destructive methods.

Aim: To evaluate the intralesional Candida antigen injection for the treatment of multiple warts in diabetic patients. Read More

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Genome-wide identification of methylated CpG sites in nongenital cutaneous warts.

BMC Med Genomics 2020 07 8;13(1):100. Epub 2020 Jul 8.

Department of Internal Medicine, Jordan University of Science and Technology, Irbid, 22110, Jordan.

Background: Low-risk HPV infection has not been the subject of epigenetic investigation. The present study was carried out in order to investigate the methylation status of CpG sites in non-genital cutaneous warts.

Methods: Genomic DNA was extracted from 24 paired epidermal samples of warts and normal skin. Read More

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CO laser treatment for plantar warts in children: A case series.

Dermatol Ther 2020 05 27;33(3):e13414. Epub 2020 Apr 27.

Molecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Several types of human papillomaviruses induce warts. Warts are one of the most common infections in childhood with a reported prevalence of up to 20%. Warts are divided clinically into genital and nongenital forms. Read More

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A comprehensive review of treatment options for recalcitrant nongenital cutaneous warts.

J Dermatolog Treat 2020 Mar 11:1-18. Epub 2020 Mar 11.

Division of Dermatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

The treatment of recalcitrant nongenital cutaneous warts has always been challenging for dermatologists as they often recur and relapse. Multiple treatment options have been investigated to improve the outcome. This review provides an overview of the current treatment modalities and summarizes the efficacy and side effects of each treatment option for recalcitrant nongenital cutaneous warts. Read More

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Evaluation of different concentrations of hydrogen peroxide solution (3% and 6%) as a potential new therapeutic option of nongenital warts: A randomized controlled triple-blinded clinical trial.

J Cosmet Dermatol 2020 Feb 8;19(2):416-422. Epub 2019 Jun 8.

Dermatology, Venereology and Andrology Department, Faculty of Medicine, Assiut University, Assiut, Egypt.

Background: Warts are common viral skin infections caused by human papillomavirus. None of the available treatment modalities fulfills the criteria of an ideal treatment option.

Objectives: To evaluate the efficacy and safety of hydrogen peroxide (HP) 3% and 6% solution as a topical treatment of nongenital warts. Read More

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February 2020

The Ring Verruca Plantaris in Cantharidin Use .

J Am Podiatr Med Assoc 2018 Mar;108(2):189-193

Verrucae (warts) are the most common viral infections of the skin, affecting 7% to 10% of the general population. Typically caused by human papillomavirus type 1, plantar warts manifest as benign proliferation of the epithelial cells on the feet. It has been cited that up to one-third of nongenital warts become recalcitrant, and biopsy is often required to confirm diagnosis and direct appropriate treatment. Read More

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Intralesional immunotherapy compared to cryotherapy in the treatment of warts.

Int J Dermatol 2017 Apr 21;56(4):474-478. Epub 2017 Jan 21.

Cutaneous Leishmaniasis Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Background: Warts are the most common clinical manifestation of the human papilloma-virus infection in the skin and mucous membranes. In spite of the various therapeutic modalities for nongenital skin warts, there is still no single method to be used as an approved treatment. In this study, we compared the efficacy of immunotherapy and cryotherapy on wart lesions. Read More

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Can We Predict the Effectiveness of Intralesional Immunotherapy in Recalcitrant Warts?

Skinmed 2016;14(6):413-421. Epub 2016 Dec 1.

Department of Dermatology, Maulana Azad Medical College, New Delhi, India.

Immunotherapy has been used for recalcitrant, large, and multiple warts, although it is difficult to predict which patient will respond. An open interventional cohort trial was conducted in 50 adult patients with recalcitrant multiple, nongenital warts in whom intralesional immunotherapy was given using the vaccine. The authors determined whether the wart resolution was dependent on the immune response. Read More

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September 2018

What works best for nongenital warts?

Can Fam Physician 2016 Dec;62(12):997

Associate Professor in the Department of Family Medicine, at the University of Alberta in Edmonton.

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December 2016

Laser Treatment of Nongenital Verrucae: A Systematic Review.

JAMA Dermatol 2016 09;152(9):1025-34

Department of Dermatology, University of California Irvine School of Medicine.

Importance: Although cutaneous warts are common lesions, full remission is not always achieved with conventional therapies. Laser modalities including carbon dioxide (CO2), erbium:yttrium-aluminum-garnet (Er:YAG), pulsed dye (PDL), and Nd:YAG have been investigated as alternative treatments for warts.

Objective: To review the use and efficacy of lasers for treating nongenital cutaneous warts. Read More

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September 2016

Clinicoepidemiological Study of Different Types of Warts.

Dermatol Res Pract 2016 7;2016:7989817. Epub 2016 Mar 7.

Department of Dermatology, Dr. D. Y. Patil Medical College and Hospital, Pimpri, Pune 411018, India.

Background. Warts are cutaneous and, sometimes, mucosal lesions caused by one of the several human papilloma viruses. Aim. Read More

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Human papillomavirus type 2 associated with pyogenic granuloma in patients without clinical evidence of warts.

Int J Dermatol 2016 Jul 22;55(7):745-50. Epub 2015 Oct 22.

Centro de Investigación y Desarrollo en Ciencias de la Salud (CIDICS), Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico.

Background: Pyogenic granuloma is a non-neoplastic lesion that frequently occurs in the skin and mucous membranes of children and pregnant women. The anatomical sites of pyogenic granulomas overlap with those of wart infections caused by the human papillomavirus (HPV).

Objective: This study assessed the presence of HPV DNA in pyogenic granuloma samples by polymerase chain reaction. Read More

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Metastatic Calcinosis Cutis: A Case in a Child with Acute Pre-B Cell Lymphoblastic Leukemia.

Case Rep Hematol 2015 5;2015:384821. Epub 2015 Aug 5.

Department of Dermatology, Hospital Central Dr. Ignacio Morones Prieto, Universidad Autónoma de San Luis Potosí, 78210 San Luis Potosí, SLP, Mexico.

Hypercalcemia in children with malignancy is an uncommon condition. It has been described in leukemia patients with impaired renal excretion of calcium or osteolytic lesions. Metastatic calcinosis cutis (MCC) may develop if hypercalcemia persists. Read More

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September 2015

HPV Carcinomas in Immunocompromised Patients.

J Clin Med 2015 Jan 29;4(2):260-81. Epub 2015 Jan 29.

Medical School, the University of Texas Health Science Center at Houston, 1401 Binz, Suite 200, Houston, TX 77004, USA.

Human papillomavirus (HPV) infection is the most common sexually transmitted disease worldwide and can result in pre-malignancies or overt malignancies of the skin and mucosal surfaces. HPV-related illnesses are an important personal and public health problem causing physical, mental, sexual and financial detriments. Moreover, this set of malignancies severely affects the immunosuppressed population, particularly HIV-positive patients and organ-transplant recipients. Read More

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January 2015

Maturation of the human papillomavirus 16 capsid.

mBio 2014 Aug 5;5(4):e01104-14. Epub 2014 Aug 5.

Imaging Sciences Laboratory, Center for Information Technology, NIH, Bethesda, Maryland, USA

Papillomaviruses are a family of nonenveloped DNA viruses that infect the skin or mucosa of their vertebrate hosts. The viral life cycle is closely tied to the differentiation of infected keratinocytes. Papillomavirus virions are released into the environment through a process known as desquamation, in which keratinocytes lose structural integrity prior to being shed from the surface of the skin. Read More

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Acquired progressive lymphangioma in the inguinal area mimicking giant condyloma acuminatum.

Cutis 2014 Jun;93(6):316-9

The Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Rd, Hangzhou, Zhejiang 310009, China.

Lymphangioma is a benign proliferation of the lymphatic vessels that accounts for approximately 4% of vascular malformations and 26% of benign vascular tumors. Compared to those arising in nongenital areas, lymphangiomas of the vulva and genital areas are more hyperplastic, possibly due to the loose connective tissue, which can cause a cauliflowerlike appearance and may easily be misdiagnosed as genital warts or molluscum contagiosum. We report a case of acquired progressive lymphangioma (APL) of the inguinal area that mimicked giant condyloma acuminatum and showed favorable results following surgical excision. Read More

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α- and β-papillomavirus infection in a young patient with an unclassified primary T-cell immunodeficiency and multiple mucosal and cutaneous lesions.

J Am Acad Dermatol 2014 Jul 4;71(1):108-15.e1. Epub 2014 Mar 4.

Virology Unit, Department of Translational Medicine, Medical School of Novara, Novara, Italy. Electronic address:

Background: Correlating human papillomavirus (HPV) type with the clinical and histopathological features of skin lesions (from genital and nongenital sites) can present a diagnostic challenge.

Objective: In this study, HPV infection patterns were correlated with pathology and clinical presentation in lesional and nonlesional body sites from a young patient with a primary T-cell immunodeficiency.

Methods: HPV infection was evaluated at both DNA and protein levels by polymerase chain reaction and immunohistochemistry. Read More

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Hyfrecation for recalcitrant nongenital warts.

Authors:
Lawrence Leung

J Family Med Prim Care 2013 Apr;2(2):141-4

Department of Family Medicine, Queen's University, Kingston, Ontario, Canada.

Background: Verruca vulgaris is a common skin condition in general practice, which often resolves without treatment. For lesions needing treatment, they often persist despite repeated treatment and become recalcitrant warts. Hyfrecation is a form of electrosurgery which has been used in treating common and recalcitrant warts. Read More

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Nongenital human papillomavirus disease.

Obstet Gynecol Clin North Am 2013 Jun 29;40(2):317-37. Epub 2013 Mar 29.

Department of Family Medicine, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA.

Human papillomavirus (HPV) is the most common viral cause of cancer, and is responsible for 5% of cancers worldwide. Following demonstration of the causative link between HPV and cervical cancer, HPV has been shown to be associated with several anogenital malignancies and with oral pharyngeal cancers. HPV-related anal and oral pharyngeal disease is rising in incidence and includes anal warts and neoplasia, recurrent respiratory papillomatosis, and oral pharyngeal neoplasia. Read More

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FPIN's clinical inquiries. Treatment of nongenital warts.

Am Fam Physician 2011 Dec;84(11):1290-1

Swedish Family Medicine, Seattle, WA, USA.

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December 2011

Treatment of nongenital cutaneous warts.

Am Fam Physician 2011 Aug;84(3):288-93

Oakland University William Beaumont School of Medicine, Rochester Hills, MI, USA.

Numerous treatments for nongenital cutaneous warts are available, although no single therapy has been established as completely curative. Watchful waiting is an option for new warts because many resolve spontaneously. However, patients often request treatment because of social stigma or discomfort. Read More

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Recalcitrant nongenital warts.

Authors:
Lawrence Leung

Aust Fam Physician 2011 Jan-Feb;40(1-2):40-2

Department of Family Medicine, Queen's University, Kingston, Ontario, Canada.

Nongenital warts are a common presentation in general practice. Despite treatment according to evidence based guidelines, a significant proportion of common warts fail to resolve, becoming recalcitrant. This poses a problem in clinical management. Read More

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Treating common warts - options and evidence.

Authors:
Lawrence Leung

Aust Fam Physician 2010 Dec;39(12):933-7

Department of Family Medicine, Queen's University, Kingston, Ontario, Canada.

Background: Nongenital warts are a common condition seen in general practice, affecting patients of all ages. There are many treatment options and patients often self medicate with remedies from folklore or tradition before presenting to their doctor.

Objective: This article attempts to summarise the quality of different treatments and to provide recommendations and a quick reference for treating common warts. Read More

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December 2010

Evaluation of a novel broad-spectrum PCR-multiplex genotyping assay for identification of cutaneous wart-associated human papillomavirus types.

J Clin Microbiol 2010 May 17;48(5):1706-11. Epub 2010 Mar 17.

DDL Diagnostic Laboratory, Fonteijnenburghlaan 7, 2275 CX Voorburg, Netherlands.

A large number of human papillomavirus (HPV) types, distributed over five papillomavirus genera, are detectable in the skin. HPV types belonging to the alpha, gamma, and mu genera have been detected in cutaneous warts. A state-of-the-art HPV genotyping assay for these cutaneous wart-associated HPV types does not exist although warts constitute a highly prevalent skin condition, especially in children (33%) and organ transplant recipients (45%). Read More

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Dermatologic manifestations of HPV in HIV-infected individuals.

Curr HIV/AIDS Rep 2009 Aug;6(3):130-8

University of Pennsylvania, Department of Dermatology, Philadelphia, PA 19104, USA.

Dermatologic human papillomavirus (HPV) infection in HIV patients manifests as both anogenital and nongenital skin disease. Anogenital HPV-related disease includes benign condyloma acuminata, the most common cutaneous manifestation of genital HPV infection; intermediate malignancy or premalignant conditions including giant condyloma acuminata (also called Buschke-Loewenstein tumor), anal intraepithelial neoplasia, penile intraepithelial neoplasia, and vaginal or vulvar intraepithelial neoplasia; and frankly malignant disease including Bowen's disease and invasive anal, penile, or vulvar carcinoma. Cutaneous HPV-related disease in nongenital skin is also increased in HIV-positive patients, in the form of benign common warts, epidermodysplasia verruciformis-like skin lesions, and nonmelanoma skin cancers. Read More

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Skin disease in HIV-positive persons living in Puerto Rico.

Adv Skin Wound Care 2007 Mar;20(3):149-50, 152-6

University of Puerto Rico, Medical Sciences Campus, School of Nursing, San Juan, PR.

Objectives: To determine the frequency of skin disease in persons infected with the human immunodeficiency virus (HIV), to validate the agreement of self-reported skin condition(s) versus objective data obtained by physical examination, and to describe the characteristics of HIV-positive persons with skin disease in Puerto Rico.

Design: Descriptive correlational design.

Setting And Participants: Ninety-five HIV-positive adults in San Juan, Puerto Rico. Read More

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Verruca vulgaris of the vulva in children and adults: a nonvenereal type of vulvar wart.

Am J Surg Pathol 2007 Apr;31(4):529-35

Department of Pathology, The Ohio State University Medical Center, Columbus, OH, USA.

Condyloma acuminata are common lesions of the vulva in adults, and associated with infection by human papillomavirus (HPV) types 6 and 11, which are acquired via sexual contact. The detection of an HPV 6/11 condyloma in the genital tract of a child, therefore, raises the question of sexual abuse. In this study, 29 genital warts in girls less than 5 years of age were examined for nongenital and genital tract HPVs by in situ hybridization. Read More

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Clinical inquiries. What nonpharmacological treatments are effective against common nongenital warts?

J Fam Pract 2006 Sep;55(9):801-2

Shenandoah Valley Family Practice Residency, Department of Family Medicine, Virginia Commonwealth University, Front Royal, VA USA.

Cryotherapy has similar cure rates to topical salicylate (a pharmacologic therapy) for nongenital common warts (strength of recommendation [SOR]: B, based on systemic review of variable quality randomized trials). Duct tape may be equivalent to cryotherapy (SOR: B, based on a single randomized trial). CO2 laser, photodynamic therapy, pulsed dye laser (PDL), and Er:Yag laser therapies may also be effective for recalcitrant warts (SOR: C, based on observational cohort studies). Read More

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September 2006