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    Cross-sectional associations between psychological traits, and HPV vaccine uptake and intentions in young adults from the United States.
    PLoS One 2018 23;13(2):e0193363. Epub 2018 Feb 23.
    Department of Epidemiology, University of Iowa, Iowa City, Iowa, United States of America.
    Human papillomavirus (HPV) is the most prevalent sexually transmitted infection worldwide and can lead to the development of genital warts, and cancers throughout the body. Despite the availability of HPV vaccines for over a decade, uptake in the United States among adolescents and young adults remains well below national targets. While most efforts to improve HPV vaccine uptake have rightly focused on adolescents, there is still a tremendous opportunity to improve vaccination among young adults who have not been vaccinated against HPV. Read More

    Resource Use and Cost of Treating Human Papillomavirus-Related Lesions in Japanese Women.
    Value Health Reg Issues 2017 Sep 1;15:56-62. Epub 2017 Sep 1.
    Health Economics, Vaccines Value and Health Science, GSK, Wavre, Belgium.
    Background: Human papillomavirus (HPV) infection is established as a necessary causal factor in several pathologies including cervical cancer (CC), which recorded over 11,000 new cases in 2011 in Japan. Nevertheless, cost burden data of human papillomavirus-related diseases in Japan are lacking.

    Objectives: To evaluate resource use and costs in women with HPV-related lesions. Read More

    Genital Wart and HPV Prevalence in Males in the United States from Penile Swabs: Results from NHANES.
    Sex Transm Dis 2017 Nov 16. Epub 2017 Nov 16.
    Department of Urology, SUNY Upstate Medical University, Syracuse, NY.
    Introduction: Human papillomavirus (HPV) is a common sexually transmitted infection in the US that can lead to both malignant (high risk) and benign (low risk) findings. These low risk findings include both genital condyloma, anal warts, and adult or juvenile papillomatosis, which are directly attributable to subtypes HPV 6 and HPV 11. We aim to estimate the prevalence of genital wart infections in males in the US population using a nationwide sample. Read More

    Characterization of HIV Recent Infection Among High-Risk Men at Public STI Clinics in Mumbai.
    AIDS Behav 2018 Feb 16. Epub 2018 Feb 16.
    University of California, San Francisco, San Francisco, CA, USA.
    We examined associations with HIV recent infection and estimated transmitted drug resistance (TDR) prevalence among 3345 men at sexually transmitted infection clinics in Mumbai (2002-2005). HIV seroincidence was 7.92% by the BED-CEIA and was higher at a clinic located near brothels (12. Read More

    Giant genital warts.
    Clin Case Rep 2018 Feb 5;6(2):444-445. Epub 2018 Jan 5.
    2nd Department of SurgerySchool of MedicineAretaieion University HospitalNational and Kapodistrian University of Athens University of Athens76 Vassilisis Sofia's AveAthens11528Greece.
    Genital warts are quite common and should be treated early with nonaggressive conservative or invasive methods. When they are severely neglected patients may be submitted to amputative surgical management. Preoperatively malignant transformation of the tumors cannot be excluded. Read More

    S2k guideline: HPV-associated lesions of the external genital region and the anus - anogenital warts and precancerous lesions of the vulva, the penis, and the peri- and intra-anal skin (short version).
    J Dtsch Dermatol Ges 2018 Feb;16(2):242-255
    Department of Dermatology, Venereology and Allergology, Division of Evidence-based Medicine in Dermatology (dEBM), Charité - Universitätsmedizin Berlin, corporate member of Free University Berlin, Humboldt University Berlin, and Berlin Institute of Health, Berlin, Germany.

    Incidence of diseases primarily affecting the skin by age group: population-based epidemiologic study in Olmsted County, Minnesota, and comparison with age-specific incidence rates worldwide.
    Int J Dermatol 2018 Jan 29. Epub 2018 Jan 29.
    Division of Clinical Dermatology, Mayo Clinic, Rochester, MN, USA.
    Understanding the effects of age on the epidemiology of diseases primarily affecting the skin is important to the practice of dermatology, both for proper allocation of resources and for optimal patient-centered care. To fully appreciate the effect that age may have on the population-based calculations of incidence of diseases primarily affecting the skin in Olmsted County, Minnesota, and worldwide, we performed a review of all relevant Rochester Epidemiology Project-published data and compared them to similar reports in the worldwide English literature. Using the Rochester Epidemiology Project, population-based epidemiologic studies have been performed to estimate the incidence of specific skin diseases over the past 50 years. Read More

    Self-reported genital warts among sexually-active university students: a cross-sectional study.
    BMC Infect Dis 2018 01 15;18(1):41. Epub 2018 Jan 15.
    Department of Cardiac, Thoracic and Vascular Sciences, Public Health Unit, University of Padua, Padua, Italy.
    Background: Genital warts are one of the most common forms of sexually-transmitted disease, but their epidemiology has yet to be thoroughly elucidated. The present study was designed to shed light on the prevalence of clinically-confirmed, self-reported genital warts (GWs) in a representative sample of the university population.

    Methods: In 2015, a cross-sectional survey was conducted on 11,096 individuals approached at the Students Information Bureau where they came to enroll for a university degree course. Read More

    HPV Unvaccinated Status and HPV Sexual Risk Behaviour are Common among Canadian Young Adult Women and Men.
    J Obstet Gynaecol Can 2017 Dec 21. Epub 2017 Dec 21.
    Department of Obstetrics and Gynaecology, Schulich School of Medicine and Dentistry, Western University, London, ON; Department of Psychology, Western University, London, ON.
    Objective: The current research focuses on sexual risk behaviour among young adult Canadians who have not been vaccinated against HPV.

    Methods: Six hundred and forty-six Canadian university undergraduates completed a self-administered survey assessing HPV vaccination status and sexual risk behaviour.

    Results: Five hundred and thirty-seven participants (154 men and 383 women aged 17-23) who met eligibility criteria were analyzed. Read More

    Clinical and economic impact of school-based nonavalent human papillomavirus vaccine on women in Singapore: a transmission dynamic mathematical model analysis.
    BJOG 2018 Mar;125(4):478-486
    Center for Observational and Real World Evidence, Merck & Co., Inc., Kenilworth, NJ, USA.
    Objective: To examine the epidemiological and economic impact of a nine-valent (nonavalent) human papillomavirus (HPV) 6/11/16/18/31/33/45/52/58 vaccine programme for young teenagers in Singapore.

    Design: Mathematical modelling.

    Setting: Pharmaco-economic simulation projection. Read More

    [Unusual location of giant seborrhoeic keratoses].
    Pan Afr Med J 2017 25;28:72. Epub 2017 Sep 25.
    Service de Dermatologie et Vénérologie, Centre Hospitalier Universitaire IBN Sina, Faculté de Médecine et de Pharmacie, Université Mohammed V, Rabat, Maroc.
    Seborrhoeic keratoses (SK) are benign tumors that mainly occur in the head and in the trunk. Their size generally varies from a few millimeters up to a few centimeters. Giant lesions are very rare but pose a problem in terms both of treatment and transformation. Read More

    Dermatologic manifestations among human immunodeficiency virus patients in Morocco and association with immune status.
    Int J Dermatol 2018 Feb 15;57(2):156-161. Epub 2017 Dec 15.
    Dermatology Department, Military Hospital Instruction Mohammed V, University Mohammed V, Rabat, Morocco.
    Objective: The objective was to determine if the type and number of skin diseases can be clinical indicators of underlying immune status in HIV1 disease by estimating and correlating with the CD4 count and CDC stage.

    Materials And Methods: This was a retrospective cross-sectional descriptive study. All consecutive patients infected with HIV1 followed at the Dermatology Department of Rabat Military Hospital between January 2008 and January 2017 were studied for dermatological manifestations, CD4 count and CDC clinical stage. Read More

    Annual prevalence and economic burden of genital warts in Korea: Health Insurance Review and Assessment (HIRA) service data from 2007 to 2015.
    Epidemiol Infect 2018 Jan 13;146(2):177-186. Epub 2017 Dec 13.
    Department of Interdisciplinary Programme in Biomedical Science,Soonchunhyang University Graduate School,Asan,Korea.
    This study evaluated the annual prevalence of anogenital warts (AGW) caused by human papillomavirus (HPV) and analysed the trend in annual per cent changes (APC) by using national claims data from the Health Insurance Review and Assessment of Korea, 2007-2015. We also estimated the socio-economic burden and co-morbidities of AGW. All analyses were performed based on data for primary A63. Read More

    Efficacy of pulsed dye laser treatment for common warts is not influenced by the causative HPV type: a prospective study.
    Lasers Med Sci 2017 Dec 7. Epub 2017 Dec 7.
    Photodermatoses Clinic, Laser Unit, Dermatology Department, Rabin Medical Center, Petach Tikva, Israel.
    Verruca vulgaris (VV) is a prevalent skin condition caused by various subtypes of human papilloma virus (HPV). The most common causes of non-genital lesions are HPV types 2 and 4, and to a lesser extent types 1, 3, 26, 29, and 57. Although numerous therapeutic modalities exist, none is universally effective or without adverse events (AE). Read More

    Modelling the effects of quadrivalent Human Papillomavirus (HPV) vaccination in Puerto Rico.
    PLoS One 2017 30;12(11):e0184540. Epub 2017 Nov 30.
    Health Outcomes Research Regional Lead, Latin America Medical Affairs, Merck & Co, San Juan, Puerto Rico.
    Background: No study has estimated the potential impact of Human Papillomavirus (HPV) vaccination in Puerto Rico, a population with considerable burden of HPV-related morbidities. We evaluated the health and economic impacts of implementing a vaccination strategy for females and males in Puerto Rico, with the quadrivalent HPV (HPV4) vaccine, under different vaccination scenarios.

    Methods: We adapted a mathematical model which estimates the direct and indirect health benefits and costs of HPV4 vaccination in a dynamic population. Read More

    Prevalence and correlates of cervical HPV infection in a clinic-based sample of HIV-positive Hispanic women.
    Papillomavirus Res 2017 Dec 19;4:39-44. Epub 2017 Jun 19.
    Maternal-Infant Studies Center (CEMI), Department of OB-GYN, University of Puerto Rico School of Medicine, San Juan, PR, United States; Department of OB-GYN, University of Puerto Rico School of Medicine, San Juan, PR, United States.
    Objectives: Puerto Rico (PR), is the fifth highest jurisdiction of the United States of America (US) with respect to HIV prevalence and the leading in cervical cancer incidence. This cross-sectional study describes the prevalence and correlates of cervical HPV infection among a clinic-based sample of 302 women living with HIV/AIDS in PR.

    Methods: Data collection included questionnaires, blood and cervical samples. Read More

    Dynamics of HPV Viral Loads Reflect the Treatment Effect of Photodynamic Therapy in Genital Warts.
    Photodiagnosis Photodyn Ther 2017 Nov 15. Epub 2017 Nov 15.
    Department of Dermatology and Venereology, Nanfang hospital, Southern Medical University, Guangzhou, 510515, China. Electronic address:
    Background: Photodynamic therapy (PDT) has demonstrated good clinical cure rates and low recurrence rates in the treatment of genital warts. Human papillomavirus (HPV) genotypes and viral load assays can reflect the status of persistent or latent infection and serve as a predictor of infection clearance.

    Methods: Specimens from 41 patients with HPV infection were obtained, and the HPV genotypes and viral load were analyzed using real-time polymerase chain reaction (PCR) assays. Read More

    Presence of infection and analysis of HPV subtypes in girls younger than 9 years old attended at a referral service in Espírito Santo, Brazil.
    J Med Virol 2018 Apr 28;90(4):761-766. Epub 2017 Nov 28.
    Núcleo de Genética Humana e Molecular, Departamento de Ciências Biológicas, Centro de Ciências Humanas e Naturais, Universidade Federal do Espírito Santo, Vitória, Espírito Santo, Brazil.
    Human papillomavirus (HPV) is found in adults and adolescents and is associated with genital warts and cervical cancer. However, it has been detected in girls younger than 10 years old. Currently, there are no prevention methods for this age group, since it is not considered a risk group. Read More

    A Prospective Study of the Incidence of Juvenile-Onset Recurrent Respiratory Papillomatosis After Implementation of a National HPV Vaccination Program.
    J Infect Dis 2018 Jan;217(2):208-212
    National HPV Vaccination Program Register, VCS, East Melbourne.
    Background: Recurrent respiratory papillomatosis is a rare but morbid disease caused by human papillomavirus (HPV) types 6 and 11. Infection is preventable through HPV vaccination. Following an extensive quadrivalent HPV vaccination program (females 12-26 years in 2007-2009) in Australia, we established a method to monitor incidence and demographics of juvenile-onset recurrent respiratory papillomatosis (JORRP) cases. Read More

    Multimodal Counseling Interventions: Effect on Human Papilloma Virus Vaccination Acceptance.
    Healthcare (Basel) 2017 Nov 6;5(4). Epub 2017 Nov 6.
    Department of Interdisciplinary Sciences, A. T. Still University, Mesa, AZ 85026, USA.
    Human papilloma virus (HPV) vaccine was developed to reduce HPV-attributable cancers, external genital warts (EGW), and recurrent respiratory papillomatosis. Adolescent HPV vaccination series completion rates are less than 40% in the United States of America, but up to 80% in Australia and the United Kingdom. Population-based herd immunity requires 80% or greater vaccination series completion rates. Read More

    [A man with strange genital warts].
    Ned Tijdschr Geneeskd 2017 ;161(0):D1715
    Catharina Ziekenhuis, afd. Dermatologie, Eindhoven.
    A 36-year-old man came to the outpatient dermatology department with asymptomatic, skin-coloured to white/yellow, firm papules on his prepuce. Over the last 10 years he had received different treatments for condylomata accuminata, with no effect. After shave excision, the diagnosis of idiopathic calcinosis cutis was made. Read More

    Burden of Disease of Human Papillomavirus (HPV): Hospitalizations in the Marche and Veneto Regions. An observational study.
    Clin Drug Investig 2018 Feb;38(2):173-180
    Hygiene and Public Health Unit, Department of Cardiac, Thoracic and Vascular Sciences, Institute of Hygiene, University of Padua, Via Loredan, 18, 35121, Padova, Italy.
    Background And Objectives: HPV (human papillomavirus) is the virus most often responsible for sexually transmitted infections. The burden of HPV-related diseases on hospital resources represents a major public health problem. The aim of this study was to assess the economic burden of HPV-related diseases (anal cancer, genital cancer, genital warts, oropharyngeal cancer) on hospital resources in two Italian regions. Read More

    Monitoring the impact of HPV vaccine in males-Considerations and challenges.
    Papillomavirus Res 2016 Dec 17;2:106-111. Epub 2016 May 17.
    University of British Columbia and BC Women's Hospital and Health Centre, 4500 Oak Street, Vancouver, BC, Canada V6H 3N1.
    In this article, we examine the issues involved if national or sub-national programs are considering extending post HPV vaccine introduction monitoring to include males. Vaccination programs are now being extended to include males in some countries, in order to improve population level HPV infection control and to directly prevent HPV-related disease in males such as anogenital warts and anal cancers. Coverage and adverse events surveillance are essential components of post-vaccination monitoring. Read More

    HPV knowledge, burden and genital wart location among heterosexually identified versus homosexually identified men who have sex with men in Lima, Peru: cross-sectional results from a cohort study.
    BMJ Open 2017 Oct 24;7(10):e017338. Epub 2017 Oct 24.
    Department of Social Medicine and Population Health, Center for Healthy Communities, School of Medicine, University of California, Riverside, California, USA.
    Objectives: The relationship between sexual practices, identity and role among Latino men who have sex with men (MSM) and HIV risk is the subject of ongoing investigation but less is known about how these aspects of sexuality relate to human papilloma-virus (HPV), an independent risk factor for HIV. This observational study investigated the relationship between HPV and sexual practices, identity and role as well as other sexually transmitted infection (STI)/HIV risk factors among HIV-negative heterosexually and homosexually identified Peruvian MSM.

    Setting: Community-based clinic for MSM in Lima, Peru. Read More

    How I treat warts, hypogammaglobulinemia, infections, and myelokathexis syndrome.
    Blood 2017 12 24;130(23):2491-2498. Epub 2017 Oct 24.
    Service d'Hémato-Oncologie Pédiatrique Registre des neutropénies congénitales, Hôpital Trousseau, Assistance Publique Hôpitaux de Paris, Paris, France.
    Warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome is a genetic disease characterized by neutropenia, lymphopenia, susceptibility to infections, and myelokathexis, which describes degenerative changes of mature neutrophils and hyperplasia of bone marrow myeloid cells. Some patients present with hypogammaglobulinemia and/or refractory warts of skin and genitalia. Congenital cardiac defects constitute uncommon manifestations of the disease. Read More

    The prevalence and concordance of human papillomavirus infection in different anogenital sites among men and women in Liuzhou, China: A population-based study.
    Int J Cancer 2018 Mar 17;142(6):1244-1251. Epub 2017 Nov 17.
    State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Strait Collaborative Innovation Center of Biomedicine and Pharmaceutics, School of Public Health, Xiamen University, Xiamen, 361102, Fujian, China.
    Human papillomavirus (HPV) infection is the pathogenesis of anogenital cancers and genital warts in both men and women, whereas there is a scarcity of large studies focused on HPV prevalence in different anogenital sites of both sexes in the same population. From May to July 2014, 2,309 men and 2,378 women aged 18-55 were enrolled from communities in Liuzhou, China. Penis/glans penis/coronary sulcus (PGC) and perianal/anal canal (PA) specimens of men, and vaginal (VA), vulvar (VU) and PA specimens of women, were collected and genotyped for HPV. Read More

    Awareness and Knowledge Levels of 18-Year-Old and Older Individuals Regarding Human Papillomavirus (HPV) and HPV Vaccine in Hatay, Turkey.
    J Cancer Educ 2017 Oct 23. Epub 2017 Oct 23.
    Faculty of Medicine, Department of Radiation Oncology, Mustafa Kemal University, Antakya, Hatay, Turkey.
    The aim of this study was to evaluate the knowledge and awareness levels of 18-year-old and older women and men on HPV infection, HPV vaccine, and the potential risk factors in Hatay, Turkey. In our study, it was found that overall 27.0 and 23. Read More

    Random Network Models to Predict the Long-Term Impact of HPV Vaccination on Genital Warts.
    Viruses 2017 Oct 16;9(10). Epub 2017 Oct 16.
    Departamento de Ciencias de la Computación, Arquitectura de Computadores, Lenguajes y Sistemas Informáticos, Estadística e Investigación Operativa, Universidad Rey Juan Carlos, Móstoles, 28933 Madrid, Spain.
    The Human papillomaviruses (HPV) vaccine induces a herd immunity effect in genital warts when a large number of the population is vaccinated. This aspect should be taken into account when devising new vaccine strategies, like vaccination at older ages or male vaccination. Therefore, it is important to develop mathematical models with good predictive capacities. Read More

    Treatment With Quadrivalent Human Papillomavirus Vaccine for Juvenile-Onset Recurrent Respiratory Papillomatosis: Case Report and Review of the Literature.
    J Pediatric Infect Dis Soc 2017 Nov;6(4):380-385
    Vaccine Education Center.
    Although juvenile-onset recurrent respiratory papillomatosis (JoRRP) generally involves a benign tumor on the larynx and other respiratory tract areas, almost all patients with this disease require repeated surgical intervention (to prevent airway obstruction during the course of illness) and various adjuvant therapies such as interferon, cidofovir, acyclovir, ribavirin, indole-3-carbinol, HspE7, mumps vaccine, photodynamic therapy, propranolol, cimetidine, and bevacizumab. Some case reports recently described the effectiveness of the quadrivalent human papillomavirus vaccine (HPV4) as an adjuvant therapy. On the basis of these reports, we administered HPV4 to a 2-year-old boy with JoRRP. Read More

    Estimating the burden of genital warts in Taiwan.
    Sex Health 2017 Nov;14(6):485-491
    Royal Women's Hospital, 20 Flemington Road, Parkville, Vic. 3052, Australia.
    Background This study aimed to estimate the prevalence of genital warts in Taiwan among those seeking healthcare, as well as genital-warts-related healthcare resource use and costs, and self-reported genital-warts-related psychosocial impact.

    Methods: Genital warts prevalence estimates were extracted from a daily record of patients examined from 31 October 2011 to 4 May 2012 by 67 physicians in Taiwan. Physicians recorded the total number of patients and genital warts patients seen daily for 2 weeks. Read More

    9-Valent human papillomavirus vaccine: a review of the clinical development program.
    Expert Rev Vaccines 2017 Nov 9;16(11):1119-1139. Epub 2017 Oct 9.
    a Merck & Co., Inc ., Kenilworth , NJ , USA.
    Introduction: The 9-valent human papillomavirus (9vHPV) vaccine covers the same HPV types (6/11/16/18) as the quadrivalent HPV (qHPV) vaccine and 5 additional cancer-causing types (31/33/45/52/58). Epidemiological studies indicate that the 9vHPV vaccine could prevent approximately 90% of cervical cancers, 70-85% of high-grade cervical dysplasia (precancers), 85-95% of HPV-related vulvar, vaginal, and anal cancers, and 90% of genital warts. Areas covered: Study design features and key findings from the 9vHPV vaccine clinical development program are reviewed. Read More

    Skin diseases of the male external genitalia in the Tanlangai Hospital in Brazzaville, Congo.
    Med Sante Trop 2017 Aug;27(3):296-300
    CHU Brazzaville, 13 avenue Auxence-IKonga, Brazzaville, Congo.
    To determine the frequency of diseases responsible for skin lesions of the male external genitalia. This descriptive retrospective study examined the medical records of patients older than 14 years treated for genital symptoms as outpatients at the Dermatology Department of Talangaï Hospital in Brazzaville in 2009-2011. Patients' sociodemographic, medical history, clinical, and laboratory data were collected on a standardized individual form. Read More

    Cost-effectiveness of HPV vaccination in the context of high cervical cancer incidence and low screening coverage.
    Vaccine 2017 Nov 9;35(46):6329-6335. Epub 2017 Sep 9.
    Institute of Family Medicine and Public Health, University of Tartu, Tartu, Estonia.
    Background: Estonia has high cervical cancer incidence and low screening coverage. We modelled the impact of population-based bivalent, quadrivalent or nonavalent HPV vaccination alongside cervical cancer screening.

    Methods: A Markov cohort model of the natural history of HPV infection was used to assess the cost-effectiveness of vaccinating a cohort of 12-year-old girls with bivalent, quadrivalent or nonavalent vaccine in two doses in a national, school-based vaccination programme. Read More

    Lifestyle factors and oncogenic papillomavirus infection in a high-risk male population.
    PLoS One 2017 12;12(9):e0184492. Epub 2017 Sep 12.
    Department of Urology, University Hospital of Vigo, Vigo, Spain.
    Background: High risk human papillomavirus (HR-HPV) infection in males is a health issue with implications for HPV-related lesions in their partners. The identification of risk factors for male infection may improve our understanding of HR-HPV transmission and prevention. The aim of this study was to evaluate the relationships between lifestyle, genital warts and HR-HPV infection. Read More

    Tumour virus vaccines: hepatitis B virus and human papillomavirus.
    Philos Trans R Soc Lond B Biol Sci 2017 Oct;372(1732)
    Department of Pathology, University of Cambridge, Cambridge CB2 1QP, UK
    Two of the most important human oncogenic viruses are hepatitis B virus (HBV) and human papillomavirus (HPV). HBV infection has been preventable by vaccination since 1982; vaccination of neonates and infants is highly effective, resulting already in decreased rates of new infections, chronic liver disease and hepato-cellular carcinoma. Nonetheless, HBV remains a global public health problem with high rates of vertical transmission from mother to child in some regions. Read More

    Attitudes towards Human Papilloma Virus Vaccination in the Latin American Andean Region.
    Healthcare (Basel) 2017 Sep 8;5(3). Epub 2017 Sep 8.
    Obstetrics and Gynecology Locum Tenens, Salinas, CA 93902, USA.
    This commentary explores the distribution of human papilloma virus (HPV) and HPV-related diseases, and factors affecting attitudes towards HPV, HPV-related diseases, and HPV vaccination in the Latin American Andean region. Lack of knowledge of HPV, known negative attitudes or incorrect assumptions about HPV, HPV-related diseases, and HPV vaccination provide a basis upon which to develop targeted HPV awareness and preventive health media campaigns. For maximal effect, media campaigns should use the internet, radio, and television to address health care providers, parents, and students. Read More

    Cost-effectiveness of human papillomavirus vaccination in Germany.
    Cost Eff Resour Alloc 2017 4;15:18. Epub 2017 Sep 4.
    Department of Health Economics and Health Care Management, School of Public Health, Bielefeld University, Universitätsstraße 25, 33615 Bielefeld, Germany.
    Background: The aim of this study was to assess the cost-effectiveness of human papillomavirus (HPV) vaccination in addition to the current cervical cancer screening programme in Germany using a dynamic transmission model.

    Methods: Based on a mathematical model simulating the transmission dynamics and the natural history of HPV infection and associated diseases (cervical intraepithelial neoplasia, cervical cancer, and genital warts), we estimated the epidemiological and economic consequences of HPV vaccination with both the quadrivalent and bivalent vaccines. In our base case analysis, we assessed the cost-effectiveness of vaccinating 12-year-old girls with a 3-dose schedule. Read More

    Understanding the Effects of Forced Sex on Sexually Transmitted Disease Acquisition and Sexually Transmitted Disease Care: Findings From the National Survey of Family Growth (2011-2013).
    Sex Transm Dis 2017 Oct;44(10):613-618
    From the *Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, GA; and †Oak Ridge Institute for Science and Education (ORISE), Oak Ridge, TN.
    Background: Although there is evidence for heightened sexually transmitted disease (STD) acquisition among women who experienced sexual violence, little is known about their patterns of STD testing, STD diagnosis, and STD treatment.

    Methods: Data was drawn from cycle eight of the National Survey of Family Growth (2011-2013). Logistic regression analyses used SUDAAN to examine the link between forced sex and risky sexual behavior as well as forced sex and STD testing, diagnoses, treatment, and connection to care. Read More

    Recurrence of Human Papillomavirus External Genital Wart Infection Among High-Risk Adults in Montréal, Canada.
    Sex Transm Dis 2017 Nov;44(11):700-706
    From the *Clinique Médicale l'Actuel; †Sexually Transmitted Infections Unit, Institut National de Santé Publique du Québec, Montréal; ‡JSS Medical Research, Saint-Laurent; and §Merck Canada, Montréal, Québec, Canada.
    Objectives: The incidence of recurrent genital warts is not well characterized; this is especially true in a post-human papillomavirus (HPV) vaccination era. The objectives of this study were to assess the incidence of subsequent HPV-related external genital warts (EGW) episodes in high-risk male and female adults, as well as ascertain patient profile and disease characteristics, in a real-world Canadian sexual health clinical setting.

    Methods: Retrospective chart review study conducted at Clinique médicale l'Actuel, a sexual health clinic in Montréal, Québec, Canada. Read More

    Topical Imiquimod is an Effective and Safe Drug for Molluscum Contagiosum in Children.
    Acta Dermatovenerol Croat 2017 Jul;25(2):164-166
    Efstathia Pasmatzi, MD, Department of Dermatology School of Medicine University of Patras, 26504 Rio-Patras, Greece;
    Dear Editor, Molluscum contagiosum (MC) is a very common skin infection caused by a molluscipox virus gene of the poxvirus family. It usually occurs in young children, sexually active adults, and immunocompromised individuals. The typical clinical picture of this infection is characterized by asymptomatic flesh-colored, single or multiple papules, measuring 2-6 mm in diameter with a central umbilication that occur on the skin and the mucous membranes. Read More

    Efficacy and Tolerability of Polyphenon E in "Difficult-to-Treat" Multiple Genital Warts in an HIV-Positive Male Subject.
    Case Rep Dermatol 2017 May-Aug;9(2):55-59. Epub 2017 Jun 27.
    Medical Department, Difa Cooper, Caronno, Italy.
    A 55-year-old man, nonsmoker, with a HIV-positive history came to our attention in February 2017. He was on treatment with Stribild, 1 capsule daily (150 mg elvitegravir, 150 mg cobicistat, 200 mg emtricitabine, and 245 mg tenofovir disoproxil). The CD4+/CD8+ cellular count was 326/µL (normal values: 404-1,612); the CD3+/CD8+ cellular count was 819/µL (normal values: 220-1,219). Read More

    Detection of human papillomavirus in urine among heterosexual men in relation to location of genital warts and circumcision status.
    Sex Transm Infect 2017 Sep 2. Epub 2017 Sep 2.
    Melbourne Sexual Health Centre, Alfred Health, Melbourne, Victoria, Australia.
    Objective: Human papillomavirus (HPV) surveillance is important to monitor the effectiveness of national HPV vaccination programmes. Positivity of HPV in urine in men varies with different sampling methods. We aimed to determine the positivity for detection of HPV-6/11 in urine samples among men in relation to the position of genital warts and circumcision status. Read More

    Prevalence of anogenital HPV infection, related disease and risk factors among HIV-infected men in inner-city Johannesburg, South Africa: baseline findings from a cohort study.
    BMC Public Health 2017 07 4;17(Suppl 3):425. Epub 2017 Jul 4.
    Wits Reproductive Health and HIV Institute (WRHI), Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
    Background: Persistent high-risk human papillomavirus (HR-HPV) infection is associated with the development of anogenital cancers, particularly in men living with HIV (MLWH). We describe the prevalence of anogenital HPV infection, abnormal anal cytology and anogenital warts (AGWs) in MLWH in Johannesburg, and explore whether HPV infection and receipt of antiretroviral treatment is associated with detection of abnormal anal cytology and AGWs.

    Methods: We enrolled a cohort of 304 sexually-active MLWH ≥18 years, who completed a questionnaire and physical examination. Read More

    "My mom said it wasn't important": A case for catch-up human papillomavirus vaccination among young adult women in the United States.
    Prev Med 2017 Dec 18;105:1-4. Epub 2017 Aug 18.
    Department of Community and Family Health, College of Public Health, University of South Florida, 13201 Bruce B. Downs Blvd. MDC 56, Tampa, FL 33612, USA. Electronic address:
    The human papillomavirus (HPV) vaccine prevents HPV-related diseases, including anogenital cancers and genital warts. In the United States, while it is recommended to adolescents ages 11 to 12, catch-up vaccination is available for those previously unvaccinated until age 26. Parental decisions or lack of provider recommendation during adolescence are barriers to on-time vaccination. Read More

    [Medical evaluation for suspected sexual violence against girls].
    Laeknabladid 2017 Juli;103(7-8):325-330
    Introduction: Sexual violence against children is a hidden problem. Medical examination and evaluation is needed to search for possible injuries, exclude infections, procure legal evidence and ensure the child´s welfare. We assessed medical evaluations done at Landspitali University Hospital and in the Reykjavik Children's House, a specialized clinic for childhood abuse cases. Read More

    Knowledge, Beliefs and Attitudes of Somali Men in Olmsted County, Minnesota, U.S., on the Human Papillomavirus Vaccine and Cervical Cancer Screening: January 17, 2015.
    J Immigr Minor Health 2017 Aug 16. Epub 2017 Aug 16.
    School of Public Health, University of Minnesota, Minneapolis, MN, USA.
    This study explores the general knowledge of Human Papillomavirus vaccine (HPV) and cervical cancer screening (CCS) among Somali men in the U.S., who are major decision-makers in Somali households. Read More

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