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    100 years of STIs in the UK: a review of national surveillance data.
    Sex Transm Infect 2018 Apr 13. Epub 2018 Apr 13.
    Public Health England, London, UK.
    Objectives: The 1916 Royal Commission on Venereal Diseases was established in response to epidemics of syphilis and gonorrhoea in the UK. In the 100 years since the Venereal Diseases Act (1917), the UK has experienced substantial scientific, economic and demographic changes. We describe historical and recent trends in STIs in the UK. Read More

    CHAPTER 8 HPV vaccines.
    Int J Gynaecol Obstet 2006 Nov;94 Suppl 1:S81-S88
    Vaccines to prevent infection with high-risk human papillomaviruses (HPV) will help protect women against cervical cancer, and some are likely to be available within the next year. One vaccine, a quadrivalent vaccine against HPV types 6, 11, 16 and 18 and known as Garadsil ©(Merck &Co., Inc), was approved by the Federal Drug Administration (FDA) for the prevention of cervical cancer, cervical cancer precursors and vulval and vaginal cancer precursors associated with HPV 16 and 18 in June 2006. Read More

    A4. Preinvasive lesions of the cervix.
    Int J Gynaecol Obstet 2006 Nov;94 Suppl 1:S44-S49
    Low-risk human papillomaviruses (HPVs) can cause genital warts which, although benign, may provoke psychological distress because they are sexually transmitted. High-risk HPVs can cause cervical intraepithelial neoplasia and cancer. Cytology-based screening programs have significantly reduced cervical cancer morbidity and mortality where the programs have been successfully implemented. Read More

    Low rate of human papillomavirus vaccination among schoolgirls in Lebanon: barriers to vaccination with a focus on mothers' knowledge about available vaccines.
    Ther Clin Risk Manag 2018 27;14:617-626. Epub 2018 Mar 27.
    Division of Infectious Diseases, Department of Internal Medicine, Makassed General Hospital, Beirut, Lebanon.
    Background: Human papillomavirus (HPV) infection is an established predisposing factor of cervical cancer. In this study, we assessed the awareness about genital warts, cervical cancer, and HPV vaccine among mothers having girls who are at the age of primary HPV vaccination attending a group of schools in Lebanon. We also assessed the rate of HPV vaccination among these girls and the barriers to vaccination in this community. Read More

    Human papillomavirus vaccine acceptability and decision-making among adolescent boys and parents: A meta-ethnography of qualitative studies.
    Vaccine 2018 Apr 3. Epub 2018 Apr 3.
    The University of Texas at Arlington, School of Social Work, 211 S. Cooper Street, Box 19129, Arlington, Texas, USA. Electronic address:
    Objective: Genital warts and human papillomavirus (HPV)-associated cancers in men can be substantially reduced through HPV vaccination; yet, globally, HPV vaccine uptake among boys remains low. This meta-ethnography synthesizes qualitative studies to understand, in-depth, HPV vaccine acceptability and decision-making among adolescent boys and/or their parents.

    Methods: A systematic search identified qualitative studies examining HPV vaccines from the perspectives of boys and/or boys' parents. Read More

    A case of oropharyngeal infection in a human immunodeficiency virus positive bisexual male co-infected with human papilloma virus and .
    JMM Case Rep 2018 Mar 10;5(3):e005132. Epub 2018 Jan 10.
    Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India.
    Introduction: Management strategies for sexually transmitted infections (STIs) in their extragenital forms address and alone; whereas increased rates of isolation of other STI agents have been reported from various parts of the world. Their extragenital presence as a reservoir of infection emphasizes the need to screen and treat them at these sites.

    Case Presentation: A 35-year-old human immunodeficiency virus 1 infected bisexual male presented with urethral discharge and multiple ano-genital warts. Read More

    Sinecatechins 10% ointment for genital warts: Case report of a beneficial reaction in an HIV-positive woman.
    Int J STD AIDS 2018 Jan 1:956462418763888. Epub 2018 Jan 1.
    Dermatology Unit, Department of Medical, Surgical and Neuro-Sciences, University of Siena, Siena, Italy.
    Patients with HIV infection are more likely to develop anogenital warts compared to HIV-negative people and are susceptible to treatment failures and recurrences. We report a case of extensive vulvar warts in an HIV-positive woman successfully treated with sinecatechins ointment. After the failure of a combination of cryotherapy and imiquimod 5% cream, we started therapy with sinecatechins 10% ointment. Read More

    Estimation of the individual residual risk of cervical cancer after vaccination with the nonavalent HPV vaccine.
    Hum Vaccin Immunother 2018 Mar 19:1-23. Epub 2018 Mar 19.
    k Cancer Research Epidemiology Program , Catalan Institute of Oncology, IDIBELL (Spain).
    Background: The nonavalent HPV (9vHPV) vaccine is indicated for active immunisation of individuals from the age of 9 years against cervical, vulvar, vaginal and anal premalignant lesions and cancers causally related to vaccine HPV high risk types 16, 18, 31, 33, 45, 52 and 58, and to the HPV low risk types 6 and 11, causing genital warts.

    Objective: To estimate the lifetime risk (up to the age of 75 years) for developing cervical cancer after vaccinating a HPV naïve girl (e.g. Read More

    Sinecatechins ointment 10% (Veregen®) for genital warts: percutaneous penetration of epigallocatechin gallate concentrations in the stratum corneum collected by adhesive tape stripping method.
    J Eur Acad Dermatol Venereol 2018 Mar 10. Epub 2018 Mar 10.
    Amsterdam Infection and Immunity Institute (AI&II), Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

    Self-perceived risk of STIs in a population-based study of Scandinavian women.
    Sex Transm Infect 2018 Mar 9. Epub 2018 Mar 9.
    Unit of Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark.
    Objective: This study examined the associations between current behaviours/characteristics and self-perceived risk for STIs, among randomly selected women aged 18-45 years from Denmark, Norway and Sweden.

    Method: A population-based, cross-sectional, questionnaire study (paper based, web based and telephone based) was conducted during 2011-2012. We compared medium-high STI risk perception with no/low risk perception. Read More

    Substantially reduced incidence of genital warts in women and men six years after HPV vaccine availability in Sweden.
    Vaccine 2018 04 6;36(15):1917-1920. Epub 2018 Mar 6.
    Dept. of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
    Background: Between 2007 and 2011, opportunistic HPV-vaccination was available in Sweden and partially subsidized to girls aged 13-17, reaching a ∼30% overall coverage.

    Methods: All Swedish women/men aged 15-44 were followed between 2006 and 2012 for condyloma. Average annual percent changes (AAPCs) in incidence were estimated. Read More

    Genital warts treatment: Beyond imiquimod.
    Hum Vaccin Immunother 2018 Mar 5:1-5. Epub 2018 Mar 5.
    a Institute of Molecular Diagnosis and Target Therapy, First Affiliated Hospital , Guangdong Pharmaceutical University , Guangzhou , Guangdong , China.
    Genital warts are one of the most common sexually transmitted diseases worldwide. The disease is a result of infection with low-risk types of human papillomaviruses, mostly type 6 and 11. Current therapies for genital warts are mainly ablative, or alternatively topical application of imiquimod cream and sinecatechin (polyphenon E) ointment to the warts. Read More

    Para - And Intraurethral Penile Tumor - Like Condilomatosis.
    Open Access Maced J Med Sci 2018 Jan 13;6(1):110-111. Epub 2018 Jan 13.
    "Onkoderma"- Policlinic for Dermatology and Dermatologic Surgery, Sofia, Bulgaria.
    Condyloma acuminata represents an epidermal manifestation, associated with the epidermotropic human papillomavirus (HPV). They have been reported as the most common sexually transmitted disease, with prevalence exceeding 50%, increased up to 4 times, within the last two decades, as the most common side of affection are the penis, vulva, vagina, cervix, perineum, and perianal area, with increased prevalence in young, sexually active individuals. Increased attention should be focused on lesions, caused by types, with moderate (33, 35, 39, 40, 43, 45, 51-56, 58) or high risk potential (types 16, 18) for malignant transformation, leading to further development of cancers of anus, vagina, vulva and penis, as well as cancers of the head and neck. Read More

    Primary Care Provider Practices and Perceptions Regarding HPV Vaccination and Anal Cancer Screening at a Boston Community Health Center.
    J Community Health 2018 Feb 26. Epub 2018 Feb 26.
    The Fenway Institute, Fenway Health, 1340 Boylston Street, Boston, MA, 02215, USA.
    Human papillomavirus (HPV) vaccination and anal cancer screening are valuable, yet underutilized, tools in prevention of HPV-related cancers among sexual and gender minority (SGM) populations. The aim of this study was to characterize primary care providers' (PCPs) practices and perceptions pertaining to HPV vaccination and anal cancer screening. A survey assessing self-reported practice characteristics related to HPV vaccination and anal cancer screening, as well as perceived barriers to vaccination and anal cancer screening at the patient-, provider-, and system-level was distributed to PCPs at a Federally-Qualified Health Center that specializes in care for SGM populations in the greater Boston area. Read More

    Giant Condylomata Acuminata of Buschke-Lowenstein Associated With Paraneoplastic Hypercalcemia.
    J Investig Med High Impact Case Rep 2018 Jan-Dec;6:2324709618758348. Epub 2018 Feb 15.
    Kern Medical Center, Bakersfield, CA, USA.
    Low-risk human papillomavirus types 6 and 11 can manifest as giant condylomata acuminata (GCA) of Buschke-Lowenstein. Up to 50% of GCA can slowly progress over years to fungating, invasive tumors. The malignant potential is attributed to unique immune evading abilities of the human papillomavirus. Read More

    Who calls the shots? The ethics of adolescent self-consent for HPV vaccination.
    J Med Ethics 2018 Feb 24. Epub 2018 Feb 24.
    Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, Texas, USA.
    While the human papillomavirus (HPV) vaccine is medically indicated to reduce the risk of genital warts and certain types of cancer, rates of HPV vaccination repeatedly fall short of public health goals. Individual-level factors contributing to low vaccination rates are well documented. However, system-level barriers, particularly the need for parental consent, have been less explored. Read More

    Cross-sectional associations between psychological traits, and HPV vaccine uptake and intentions in young adults from the United States.
    PLoS One 2018 23;13(2):e0193363. Epub 2018 Feb 23.
    Department of Epidemiology, University of Iowa, Iowa City, Iowa, United States of America.
    Human papillomavirus (HPV) is the most prevalent sexually transmitted infection worldwide and can lead to the development of genital warts, and cancers throughout the body. Despite the availability of HPV vaccines for over a decade, uptake in the United States among adolescents and young adults remains well below national targets. While most efforts to improve HPV vaccine uptake have rightly focused on adolescents, there is still a tremendous opportunity to improve vaccination among young adults who have not been vaccinated against HPV. Read More

    Resource Use and Cost of Treating Human Papillomavirus-Related Lesions in Japanese Women.
    Value Health Reg Issues 2017 Sep 1;15:56-62. Epub 2017 Sep 1.
    Health Economics, Vaccines Value and Health Science, GSK, Wavre, Belgium.
    Background: Human papillomavirus (HPV) infection is established as a necessary causal factor in several pathologies including cervical cancer (CC), which recorded over 11,000 new cases in 2011 in Japan. Nevertheless, cost burden data of human papillomavirus-related diseases in Japan are lacking.

    Objectives: To evaluate resource use and costs in women with HPV-related lesions. Read More

    Genital Wart and HPV Prevalence in Males in the United States from Penile Swabs: Results from NHANES.
    Sex Transm Dis 2017 Nov 16. Epub 2017 Nov 16.
    Department of Urology, SUNY Upstate Medical University, Syracuse, NY.
    Introduction: Human papillomavirus (HPV) is a common sexually transmitted infection in the US that can lead to both malignant (high risk) and benign (low risk) findings. These low risk findings include both genital condyloma, anal warts, and adult or juvenile papillomatosis, which are directly attributable to subtypes HPV 6 and HPV 11. We aim to estimate the prevalence of genital wart infections in males in the US population using a nationwide sample. Read More

    Characterization of HIV Recent Infection Among High-Risk Men at Public STI Clinics in Mumbai.
    AIDS Behav 2018 Feb 16. Epub 2018 Feb 16.
    University of California, San Francisco, San Francisco, CA, USA.
    We examined associations with HIV recent infection and estimated transmitted drug resistance (TDR) prevalence among 3345 men at sexually transmitted infection clinics in Mumbai (2002-2005). HIV seroincidence was 7.92% by the BED-CEIA and was higher at a clinic located near brothels (12. Read More

    Giant genital warts.
    Clin Case Rep 2018 Feb 5;6(2):444-445. Epub 2018 Jan 5.
    2nd Department of SurgerySchool of MedicineAretaieion University HospitalNational and Kapodistrian University of Athens University of Athens76 Vassilisis Sofia's AveAthens11528Greece.
    Genital warts are quite common and should be treated early with nonaggressive conservative or invasive methods. When they are severely neglected patients may be submitted to amputative surgical management. Preoperatively malignant transformation of the tumors cannot be excluded. Read More

    S2k guideline: HPV-associated lesions of the external genital region and the anus - anogenital warts and precancerous lesions of the vulva, the penis, and the peri- and intra-anal skin (short version).
    J Dtsch Dermatol Ges 2018 Feb;16(2):242-255
    Department of Dermatology, Venereology and Allergology, Division of Evidence-based Medicine in Dermatology (dEBM), Charité - Universitätsmedizin Berlin, corporate member of Free University Berlin, Humboldt University Berlin, and Berlin Institute of Health, Berlin, Germany.

    Incidence of diseases primarily affecting the skin by age group: population-based epidemiologic study in Olmsted County, Minnesota, and comparison with age-specific incidence rates worldwide.
    Int J Dermatol 2018 Jan 29. Epub 2018 Jan 29.
    Division of Clinical Dermatology, Mayo Clinic, Rochester, MN, USA.
    Understanding the effects of age on the epidemiology of diseases primarily affecting the skin is important to the practice of dermatology, both for proper allocation of resources and for optimal patient-centered care. To fully appreciate the effect that age may have on the population-based calculations of incidence of diseases primarily affecting the skin in Olmsted County, Minnesota, and worldwide, we performed a review of all relevant Rochester Epidemiology Project-published data and compared them to similar reports in the worldwide English literature. Using the Rochester Epidemiology Project, population-based epidemiologic studies have been performed to estimate the incidence of specific skin diseases over the past 50 years. Read More

    Self-reported genital warts among sexually-active university students: a cross-sectional study.
    BMC Infect Dis 2018 01 15;18(1):41. Epub 2018 Jan 15.
    Department of Cardiac, Thoracic and Vascular Sciences, Public Health Unit, University of Padua, Padua, Italy.
    Background: Genital warts are one of the most common forms of sexually-transmitted disease, but their epidemiology has yet to be thoroughly elucidated. The present study was designed to shed light on the prevalence of clinically-confirmed, self-reported genital warts (GWs) in a representative sample of the university population.

    Methods: In 2015, a cross-sectional survey was conducted on 11,096 individuals approached at the Students Information Bureau where they came to enroll for a university degree course. Read More

    HPV Unvaccinated Status and HPV Sexual Risk Behaviour are Common among Canadian Young Adult Women and Men.
    J Obstet Gynaecol Can 2017 Dec 21. Epub 2017 Dec 21.
    Department of Obstetrics and Gynaecology, Schulich School of Medicine and Dentistry, Western University, London, ON; Department of Psychology, Western University, London, ON.
    Objective: The current research focuses on sexual risk behaviour among young adult Canadians who have not been vaccinated against HPV.

    Methods: Six hundred and forty-six Canadian university undergraduates completed a self-administered survey assessing HPV vaccination status and sexual risk behaviour.

    Results: Five hundred and thirty-seven participants (154 men and 383 women aged 17-23) who met eligibility criteria were analyzed. Read More

    Clinical and economic impact of school-based nonavalent human papillomavirus vaccine on women in Singapore: a transmission dynamic mathematical model analysis.
    BJOG 2018 Mar;125(4):478-486
    Center for Observational and Real World Evidence, Merck & Co., Inc., Kenilworth, NJ, USA.
    Objective: To examine the epidemiological and economic impact of a nine-valent (nonavalent) human papillomavirus (HPV) 6/11/16/18/31/33/45/52/58 vaccine programme for young teenagers in Singapore.

    Design: Mathematical modelling.

    Setting: Pharmaco-economic simulation projection. Read More

    [Unusual location of giant seborrhoeic keratoses].
    Pan Afr Med J 2017 25;28:72. Epub 2017 Sep 25.
    Service de Dermatologie et Vénérologie, Centre Hospitalier Universitaire IBN Sina, Faculté de Médecine et de Pharmacie, Université Mohammed V, Rabat, Maroc.
    Seborrhoeic keratoses (SK) are benign tumors that mainly occur in the head and in the trunk. Their size generally varies from a few millimeters up to a few centimeters. Giant lesions are very rare but pose a problem in terms both of treatment and transformation. Read More

    Dermatologic manifestations among human immunodeficiency virus patients in Morocco and association with immune status.
    Int J Dermatol 2018 Feb 15;57(2):156-161. Epub 2017 Dec 15.
    Dermatology Department, Military Hospital Instruction Mohammed V, University Mohammed V, Rabat, Morocco.
    Objective: The objective was to determine if the type and number of skin diseases can be clinical indicators of underlying immune status in HIV1 disease by estimating and correlating with the CD4 count and CDC stage.

    Materials And Methods: This was a retrospective cross-sectional descriptive study. All consecutive patients infected with HIV1 followed at the Dermatology Department of Rabat Military Hospital between January 2008 and January 2017 were studied for dermatological manifestations, CD4 count and CDC clinical stage. Read More

    Annual prevalence and economic burden of genital warts in Korea: Health Insurance Review and Assessment (HIRA) service data from 2007 to 2015.
    Epidemiol Infect 2018 Jan 13;146(2):177-186. Epub 2017 Dec 13.
    Department of Interdisciplinary Programme in Biomedical Science,Soonchunhyang University Graduate School,Asan,Korea.
    This study evaluated the annual prevalence of anogenital warts (AGW) caused by human papillomavirus (HPV) and analysed the trend in annual per cent changes (APC) by using national claims data from the Health Insurance Review and Assessment of Korea, 2007-2015. We also estimated the socio-economic burden and co-morbidities of AGW. All analyses were performed based on data for primary A63. Read More

    Efficacy of pulsed dye laser treatment for common warts is not influenced by the causative HPV type: a prospective study.
    Lasers Med Sci 2017 Dec 7. Epub 2017 Dec 7.
    Photodermatoses Clinic, Laser Unit, Dermatology Department, Rabin Medical Center, Petach Tikva, Israel.
    Verruca vulgaris (VV) is a prevalent skin condition caused by various subtypes of human papilloma virus (HPV). The most common causes of non-genital lesions are HPV types 2 and 4, and to a lesser extent types 1, 3, 26, 29, and 57. Although numerous therapeutic modalities exist, none is universally effective or without adverse events (AE). Read More

    Modelling the effects of quadrivalent Human Papillomavirus (HPV) vaccination in Puerto Rico.
    PLoS One 2017 30;12(11):e0184540. Epub 2017 Nov 30.
    Health Outcomes Research Regional Lead, Latin America Medical Affairs, Merck & Co, San Juan, Puerto Rico.
    Background: No study has estimated the potential impact of Human Papillomavirus (HPV) vaccination in Puerto Rico, a population with considerable burden of HPV-related morbidities. We evaluated the health and economic impacts of implementing a vaccination strategy for females and males in Puerto Rico, with the quadrivalent HPV (HPV4) vaccine, under different vaccination scenarios.

    Methods: We adapted a mathematical model which estimates the direct and indirect health benefits and costs of HPV4 vaccination in a dynamic population. Read More

    Prevalence and correlates of cervical HPV infection in a clinic-based sample of HIV-positive Hispanic women.
    Papillomavirus Res 2017 Dec 19;4:39-44. Epub 2017 Jun 19.
    Maternal-Infant Studies Center (CEMI), Department of OB-GYN, University of Puerto Rico School of Medicine, San Juan, PR, United States; Department of OB-GYN, University of Puerto Rico School of Medicine, San Juan, PR, United States.
    Objectives: Puerto Rico (PR), is the fifth highest jurisdiction of the United States of America (US) with respect to HIV prevalence and the leading in cervical cancer incidence. This cross-sectional study describes the prevalence and correlates of cervical HPV infection among a clinic-based sample of 302 women living with HIV/AIDS in PR.

    Methods: Data collection included questionnaires, blood and cervical samples. Read More

    Dynamics of HPV viral loads reflect the treatment effect of photodynamic therapy in genital warts.
    Photodiagnosis Photodyn Ther 2018 Mar 5;21:86-90. Epub 2017 Dec 5.
    Department of Dermatology and Venereology, Nanfang hospital, Southern Medical University, Guangzhou, 510515, China. Electronic address:
    Background: Photodynamic therapy (PDT) has demonstrated good clinical cure rates and low recurrence rates in the treatment of genital warts. Human papillomavirus (HPV) genotypes and viral load assays can reflect the status of persistent or latent infection and serve as a predictor of infection clearance.

    Methods: Specimens from 41 patients with HPV infection were obtained, and the HPV genotypes and viral load were analyzed using real-time polymerase chain reaction (PCR) assays. Read More

    Presence of infection and analysis of HPV subtypes in girls younger than 9 years old attended at a referral service in Espírito Santo, Brazil.
    J Med Virol 2018 Apr 28;90(4):761-766. Epub 2017 Nov 28.
    Núcleo de Genética Humana e Molecular, Departamento de Ciências Biológicas, Centro de Ciências Humanas e Naturais, Universidade Federal do Espírito Santo, Vitória, Espírito Santo, Brazil.
    Human papillomavirus (HPV) is found in adults and adolescents and is associated with genital warts and cervical cancer. However, it has been detected in girls younger than 10 years old. Currently, there are no prevention methods for this age group, since it is not considered a risk group. Read More

    A Prospective Study of the Incidence of Juvenile-Onset Recurrent Respiratory Papillomatosis After Implementation of a National HPV Vaccination Program.
    J Infect Dis 2018 Jan;217(2):208-212
    National HPV Vaccination Program Register, VCS, East Melbourne.
    Background: Recurrent respiratory papillomatosis is a rare but morbid disease caused by human papillomavirus (HPV) types 6 and 11. Infection is preventable through HPV vaccination. Following an extensive quadrivalent HPV vaccination program (females 12-26 years in 2007-2009) in Australia, we established a method to monitor incidence and demographics of juvenile-onset recurrent respiratory papillomatosis (JORRP) cases. Read More

    Multimodal Counseling Interventions: Effect on Human Papilloma Virus Vaccination Acceptance.
    Healthcare (Basel) 2017 Nov 6;5(4). Epub 2017 Nov 6.
    Department of Interdisciplinary Sciences, A. T. Still University, Mesa, AZ 85026, USA.
    Human papilloma virus (HPV) vaccine was developed to reduce HPV-attributable cancers, external genital warts (EGW), and recurrent respiratory papillomatosis. Adolescent HPV vaccination series completion rates are less than 40% in the United States of America, but up to 80% in Australia and the United Kingdom. Population-based herd immunity requires 80% or greater vaccination series completion rates. Read More

    [A man with strange genital warts].
    Ned Tijdschr Geneeskd 2017 ;161(0):D1715
    Catharina Ziekenhuis, afd. Dermatologie, Eindhoven.
    A 36-year-old man came to the outpatient dermatology department with asymptomatic, skin-coloured to white/yellow, firm papules on his prepuce. Over the last 10 years he had received different treatments for condylomata accuminata, with no effect. After shave excision, the diagnosis of idiopathic calcinosis cutis was made. Read More

    Burden of Disease of Human Papillomavirus (HPV): Hospitalizations in the Marche and Veneto Regions. An observational study.
    Clin Drug Investig 2018 Feb;38(2):173-180
    Hygiene and Public Health Unit, Department of Cardiac, Thoracic and Vascular Sciences, Institute of Hygiene, University of Padua, Via Loredan, 18, 35121, Padova, Italy.
    Background And Objectives: HPV (human papillomavirus) is the virus most often responsible for sexually transmitted infections. The burden of HPV-related diseases on hospital resources represents a major public health problem. The aim of this study was to assess the economic burden of HPV-related diseases (anal cancer, genital cancer, genital warts, oropharyngeal cancer) on hospital resources in two Italian regions. Read More

    Monitoring the impact of HPV vaccine in males-Considerations and challenges.
    Papillomavirus Res 2016 Dec 17;2:106-111. Epub 2016 May 17.
    University of British Columbia and BC Women's Hospital and Health Centre, 4500 Oak Street, Vancouver, BC, Canada V6H 3N1.
    In this article, we examine the issues involved if national or sub-national programs are considering extending post HPV vaccine introduction monitoring to include males. Vaccination programs are now being extended to include males in some countries, in order to improve population level HPV infection control and to directly prevent HPV-related disease in males such as anogenital warts and anal cancers. Coverage and adverse events surveillance are essential components of post-vaccination monitoring. Read More

    HPV knowledge, burden and genital wart location among heterosexually identified versus homosexually identified men who have sex with men in Lima, Peru: cross-sectional results from a cohort study.
    BMJ Open 2017 Oct 24;7(10):e017338. Epub 2017 Oct 24.
    Department of Social Medicine and Population Health, Center for Healthy Communities, School of Medicine, University of California, Riverside, California, USA.
    Objectives: The relationship between sexual practices, identity and role among Latino men who have sex with men (MSM) and HIV risk is the subject of ongoing investigation but less is known about how these aspects of sexuality relate to human papilloma-virus (HPV), an independent risk factor for HIV. This observational study investigated the relationship between HPV and sexual practices, identity and role as well as other sexually transmitted infection (STI)/HIV risk factors among HIV-negative heterosexually and homosexually identified Peruvian MSM.

    Setting: Community-based clinic for MSM in Lima, Peru. Read More

    How I treat warts, hypogammaglobulinemia, infections, and myelokathexis syndrome.
    Blood 2017 12 24;130(23):2491-2498. Epub 2017 Oct 24.
    Service d'Hémato-Oncologie Pédiatrique Registre des neutropénies congénitales, Hôpital Trousseau, Assistance Publique Hôpitaux de Paris, Paris, France.
    Warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome is a genetic disease characterized by neutropenia, lymphopenia, susceptibility to infections, and myelokathexis, which describes degenerative changes of mature neutrophils and hyperplasia of bone marrow myeloid cells. Some patients present with hypogammaglobulinemia and/or refractory warts of skin and genitalia. Congenital cardiac defects constitute uncommon manifestations of the disease. Read More

    The prevalence and concordance of human papillomavirus infection in different anogenital sites among men and women in Liuzhou, China: A population-based study.
    Int J Cancer 2018 Mar 17;142(6):1244-1251. Epub 2017 Nov 17.
    State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Strait Collaborative Innovation Center of Biomedicine and Pharmaceutics, School of Public Health, Xiamen University, Xiamen, 361102, Fujian, China.
    Human papillomavirus (HPV) infection is the pathogenesis of anogenital cancers and genital warts in both men and women, whereas there is a scarcity of large studies focused on HPV prevalence in different anogenital sites of both sexes in the same population. From May to July 2014, 2,309 men and 2,378 women aged 18-55 were enrolled from communities in Liuzhou, China. Penis/glans penis/coronary sulcus (PGC) and perianal/anal canal (PA) specimens of men, and vaginal (VA), vulvar (VU) and PA specimens of women, were collected and genotyped for HPV. Read More

    Awareness and Knowledge Levels of 18-Year-Old and Older Individuals Regarding Human Papillomavirus (HPV) and HPV Vaccine in Hatay, Turkey.
    J Cancer Educ 2017 Oct 23. Epub 2017 Oct 23.
    Faculty of Medicine, Department of Radiation Oncology, Mustafa Kemal University, Antakya, Hatay, Turkey.
    The aim of this study was to evaluate the knowledge and awareness levels of 18-year-old and older women and men on HPV infection, HPV vaccine, and the potential risk factors in Hatay, Turkey. In our study, it was found that overall 27.0 and 23. Read More

    Random Network Models to Predict the Long-Term Impact of HPV Vaccination on Genital Warts.
    Viruses 2017 10 16;9(10). Epub 2017 Oct 16.
    Departamento de Ciencias de la Computación, Arquitectura de Computadores, Lenguajes y Sistemas Informáticos, Estadística e Investigación Operativa, Universidad Rey Juan Carlos, Móstoles, 28933 Madrid, Spain.
    The Human papillomaviruses (HPV) vaccine induces a herd immunity effect in genital warts when a large number of the population is vaccinated. This aspect should be taken into account when devising new vaccine strategies, like vaccination at older ages or male vaccination. Therefore, it is important to develop mathematical models with good predictive capacities. Read More

    Treatment With Quadrivalent Human Papillomavirus Vaccine for Juvenile-Onset Recurrent Respiratory Papillomatosis: Case Report and Review of the Literature.
    J Pediatric Infect Dis Soc 2017 Nov;6(4):380-385
    Vaccine Education Center.
    Although juvenile-onset recurrent respiratory papillomatosis (JoRRP) generally involves a benign tumor on the larynx and other respiratory tract areas, almost all patients with this disease require repeated surgical intervention (to prevent airway obstruction during the course of illness) and various adjuvant therapies such as interferon, cidofovir, acyclovir, ribavirin, indole-3-carbinol, HspE7, mumps vaccine, photodynamic therapy, propranolol, cimetidine, and bevacizumab. Some case reports recently described the effectiveness of the quadrivalent human papillomavirus vaccine (HPV4) as an adjuvant therapy. On the basis of these reports, we administered HPV4 to a 2-year-old boy with JoRRP. Read More

    Estimating the burden of genital warts in Taiwan.
    Sex Health 2017 Nov;14(6):485-491
    Royal Women's Hospital, 20 Flemington Road, Parkville, Vic. 3052, Australia.
    Background This study aimed to estimate the prevalence of genital warts in Taiwan among those seeking healthcare, as well as genital-warts-related healthcare resource use and costs, and self-reported genital-warts-related psychosocial impact.

    Methods: Genital warts prevalence estimates were extracted from a daily record of patients examined from 31 October 2011 to 4 May 2012 by 67 physicians in Taiwan. Physicians recorded the total number of patients and genital warts patients seen daily for 2 weeks. Read More

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