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Bull Soc Pathol Exot 2018 ;111(1):1-4

Service dermatologie CHU de Treichville, université Félix Houphouët Boigny, Abidjan, Côte-d'Ivoire.

We have conducted a retrospective study in the dermatology department of the CHU Treichville in Abidjan during 4 years. Three hundred and fifty cases of venereal warts were recorded with a hospital frequency of 1.5%, an average age of 29. Read More

Acta Derm Venereol 2019 02 6. Epub 2019 Feb 6.

Department of Microbiology, University of Porto, Faculty of medicine, 4200-319 Porto, Portugal.

Human papillomavirus (HPV) infection is highly prevalent in the sexually active population. This study estimates the prevalence of HPV DNA in anal and oral samples from a cohort of men and women with incident anogenital warts. Anal and/or oral samples from 541 patients with anogenital warts were tested for 35 HPV genotypes using a PCR (polymerase chain reaction) assay. Read More

Sex Transm Infect 2019 Feb 5. Epub 2019 Feb 5.

Mortimer Market Centre, Institute for Global Health, University College London, London, UK.

Objectives: To estimate the prevalence of, and describe risk factors for, genital warts (GWs) in the British population, following the introduction of the bivalent (human papillomavirus (HPV)-16/18) vaccination programme in girls, and prior to the switch to quadrivalent (HPV-6/11/16/18) vaccine (offering direct protection against GWs) and compare this with GW diagnoses in the prevaccination era.

Methods: Natsal-3, a probability sample survey in Britain, conducted in 2010-2012, interviewed 9902 men and women aged 16-44. Natsal-2, conducted in 1999-2001, surveyed 11 161 men and women aged 16-44. Read More

JAMA 2019 02;321(5):520

Salud Publica Mex 2018 Nov-Dic;60(6):633-644

Center for Infection Research in Cancer, Moffitt Cancer Center and Research Institute.Tampa, Florida.

Objective: To determine external genital lesion (EGL) incidence -condyloma and penile intraepithelial neoplasia (PeIN)- and genital HPV-genotype progression to these EGLs.

Materials And Methods: Participants (healthy males 18- 74y from Cuernavaca, Mexico, recruited 2005-2009, n=954) underwent a questionnaire, anogenital examination, and sample collection every six months;including excision biopsy on suspicious EGL with histological confirmation.Linear array assay PCR characterized 37 high/low-risk HPV-DNA types. Read More

Salud Publica Mex 2018 Nov-Dic;60(6):624-632

Centro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública. Cuernavaca, Morelos, México.

Objective: To estimate the burden of genital warts (GW)in Mexico.

Materials And Methods: We estimated the annual incidence of GW based on data reported by specialist physicians. We also assessed GW treatment practices, the average cost of treatment, and the psychosocial burden of GW among patients. Read More

Hum Vaccin Immunother 2019 Jan 30. Epub 2019 Jan 30.

b Medical Department , MSD Spain , Madrid , Spain.

Human papillomavirus (HPV) is one of the main causes of infection-related cancer. The bivalent vaccine (2vHPV) (16/18) and quadrivalent (6/11/16/18) HPV vaccine (4vHPV) have been included in the Spanish vaccination calendar since 2007. The new nonavalent HPV vaccine (9vHPV), approved in Europe in 2015, includes nine HPV types 6/11/16/18/31/33/45/52/58 and has been available in Spain since May 2017. Read More

Hum Vaccin Immunother 2019 Jan 28. Epub 2019 Jan 28.

a Department of Cardiac, Thoracic and Vascular Sciences, Hygiene and Public Health Unit , University of Padua , Padua , Italy.

HPV is involved in cervical, anal, penile, vulvar and oropharyngeal cancers, as well as genital warts. It is important to investigate knowledge and attitudes among university students, considering in this age a shift in healthcare decision-making from parents to students themselves. The aim of this study was to estimate knowledge and perception of HPV in terms of potential shame for HPV-related conditions, trust in vaccine efficacy and worry for potential side effects. Read More

Sex Transm Infect 2019 Jan 24. Epub 2019 Jan 24.

Department of Cancer Control and Population Health, National Cancer Center Graduate School of Cancer Science and Policy, Goyang, Republic of Korea

Objective: We aimed to evaluate trends in the prevalence of human papillomavirus (HPV)-related diseases in the era before the introduction of organised HPV vaccination programmes in the Republic of Korea.

Methods: This cross-sectional study used National Health Insurance Service data from 2002 to 2015 and included participants who were diagnosed with the following HPV-related diseases (codes from the International Classification of Diseases, 10th Revision): genital warts (A63.0); cancer in the head and neck (C00-C10), anus (C21), vulva (C51), vagina (C52), cervix uteri (C53) and penis (C60); carcinoma in situ (CIS) of the lip/oral cavity/pharynx (D00. Read More

Paediatr Child Health 2018 Jul 12;23(4):262-265. Epub 2018 Jun 12.

Canadian Paediatric Society, Infectious Diseases and Immunization Committee, Ottawa, Ontario.

Human papillomavirus (HPV) is known to cause genital warts, cervical cancer, penile cancer, anal cancer and oropharyngeal cancer. In North America, the lifetime cumulative incidence of HPV infection is estimated at more than 70% for all HPV types combined. A safe and effective vaccine against nine HPV types is available. Read More

Hum Vaccin Immunother 2019 Jan 16. Epub 2019 Jan 16.

c Department of Pediatrics , Wake Forest School of Medicine and Brenner Children's Hosptial , Winston-Salem , NC , USA.

Purpose: To evaluate knowledge, attitudes and factors associated with acceptability of human papillomavirus (HPV) vaccine among undergraduate medical, dental, and nursing students in South India.

Methods: Using a post-test study design, a convenience sample of 988 students (age 18-26 years) were surveyed. The primary outcome was vaccine acceptability (likely to intend to receive the vaccine). Read More

Indian J Sex Transm Dis AIDS 2018 Jul-Dec;39(2):133-135

Department of Dermatology and Venereology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.

Genital warts have a big psychological impact on the affected individuals, as the treatment requires time and multiple sessions at a time. They can also increase the chances of acquiring other sexually transmitted diseases. Various treatment options are available including the topical application of imiquimod, podophyllin, trichloroacetic acid application, cryotherapy, and radiofrequency cautery. Read More

Drugs Context 2018 19;7:212563. Epub 2018 Dec 19.

Department of Pediatrics, The Chinese University of Hong Kong, Shatin, Hong Kong.

Background: Penile warts are the most common sexually transmitted disease in males. Clinicians should be familiar with the proper evaluation and management of this common condition.

Objective: To provide an update on the current understanding, evaluation, and management of penile warts. Read More

BMC Infect Dis 2019 Jan 7;19(1):27. Epub 2019 Jan 7.

Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, Baltimore, MD, USA.

Background: Genital warts are important causes of morbidity and their prevalence and incidence can be used to evaluate the impact of HPV vaccination in a population.

Methods: We enrolled 1020 women in a prospective cohort study in Nigeria and followed them for a mean (SD) of 9 (4) months. Nurses conducted pelvic examinations and collected ectocervical samples for HPV testing. Read More

J Egypt Public Health Assoc 2017 Dec 1;92(4):235-239. Epub 2017 Dec 1.

Department of Dermatology, King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia.

Background: Sexually transmitted infections (STIs) are increasingly becoming one of the most important health challenges , especially among women, as they bear long-term consequences such as infertility and cervical cancer owing to STIs. This study aimed to assess the knowledge and misconceptions of Saudi women about STIs.

Materials And Methods: A descriptive study was conducted among adult women attending the dermatology clinic at King Saud University Medical City, Riyadh, Saudi Arabia, for reasons other than STIs. Read More

Psychiatriki 2018 Jul-Sep;29(3):209-219

Hellenic Psychiatric Association, Athens, Greece.

This is a comparative study aiming to investigate quality of life (QoL) and depression in individuals diagnosed either with human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS), or genital warts (GW) and genital herpes (GH), in two healthcare settings, in the United Kingdom (UK) or in Greece (Gr). Using a matched-pairs design, two equalized patient samples with sexually transmitted infections (STI) were recruited: from UK (n=43) and from Greece (n=43). QoL was assessed with WHOQOL-HIV BREF for HIV patients and WHOQOL-STI BREF -a newly adapted instrument- for genital warts and genital herpes patients. Read More

J Korean Med Sci 2018 Dec 28;33(52):e331. Epub 2018 Nov 28.

Department of Obstetrics and Gynecology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

Human Papillomavirus (HPV) infection is the most common sexually transmitted infection and is associated with the development of cervical cancer. The purpose of this report is to provide the literature evidences on selecting the HPV vaccine for national immunization program (NIP) in Korea. To complete these tasks, we reviewed domestic and foreign literature on the current status of HPV infection, efficacy and effectiveness of HPV vaccine, safety of vaccine and cost effectiveness analysis of vaccination business. Read More

Photodiagnosis Photodyn Ther 2018 Dec 20. Epub 2018 Dec 20.

Department of Dermatology, the First Affiliated Hospital of Harbin Medical University, Harbin, 150001, China. Electronic address:

Background: Human papilloma virus (HPV) infection and condyloma acuminatum (CA) in the genital area are often existence in extensive and multi-point fashion. Laser ablation combined with topical photodynamic therapy (PDT) is a feasible approach for genital CA but its effectiveness and limitation need to be evaluated.

Methods: This single-arm prospective study consisted of 100 newly diagnosed CA cases of both sexes. Read More

Pan Afr Med J 2018 26;30:227. Epub 2018 Jul 26.

Department of Urology-Oncology, "Theageneio" Cancer Hospital of Thessaloniki, Thessaloniki, Greece.

Genital warts are a major worldwide healthcare problem of sexually active population. Apart from direct association with cervical cancer, male patients experience HPV-related condylomata in several locations in the anogenital area. Extensive growth, multifocality and difficult accessibility wart sites are demanding and often require multidisciplinary surgical management. Read More

Acta Dermatovenerol Alp Pannonica Adriat 2018 12;27(4):221-223

Department of Dermatology and Venereology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.

Lichen sclerosus (LS) is a chronic, inflammatory, mucocutaneous disorder of the genital and extragenital skin. Anogenital warts are benign proliferative lesions caused by human papillomavirus (HPV), which is found in > 95% of lesions. We present two cases of the coexistence of LS and genital warts: one patient with and one without a previous history of genital warts. Read More

Public Health Nurs 2018 Dec 11. Epub 2018 Dec 11.

Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia.

Objective: To increase our understanding about the health beliefs of African-American parents and their daughters toward HPV infection and HPV vaccine acceptance.

Methods: The Health Belief Model was used as a guiding framework. Principles of grounded theory, theoretical sampling, and constant comparison analysis were used to qualitatively analyze data generated from personal interviews of African-American parents (n = 30) and their 12- to 17-year-old daughters (n = 34). Read More

Expert Rev Vaccines 2018 Dec 10. Epub 2018 Dec 10.

c Department of Medicine B and Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Ramat-Gan; Sackler Faculty of Medicine , Tel-Aviv University , Tel-Aviv , Israel.

Introduction: If not properly treated, human papillomavirus (HPV) infection may evolve from a common sexually transmitted disease to genital warts and cervical cancer. Various prophylactic HPV vaccines (HPVv), approved to reduce the incidence of the infection, have been found to be effective and safe; however, accounts of post-vaccination autoimmune phenomena, including systemic lupus erythematosus (SLE), have been reported in genetically susceptible individuals. Areas covered: Infectious agents play a role in breaking the immunologic tolerance to self-antigens, resulting in autoimmune events. Read More

Int J Surg Case Rep 2019 27;54:7-9. Epub 2018 Nov 27.

Department of Plastic Surgery and Breast Surgery, Zealand University Hospital, Roskilde, Denmark.

Introduction: Verrucous carcinoma is an uncommon variant of low-grade squamous cell malignancy with a low malignant potential but a high risk of recurrence.

Presentation Of Case: We report a case of a Human Papilloma Virus negative local verrucous carcinoma in the perianal area of a 45-year old otherwise healthy female. The tumor presented clinically as a persistent genital wart not responding to usual dermatologic local therapy. Read More

J Infect Dis 2018 Nov 29. Epub 2018 Nov 29.

National Center for HIV/AIDS, Viral Hepatitis, STD, and TB; Centers for Disease Control and Prevention; Atlanta, GA, USA.

Background: Approximately 90% of genital warts are caused by human papillomavirus (HPV) types 6 and 11. In the US, HPV vaccination has been recommended for females ≤26 years; and since 2011, males ≤21 years and gay, bisexual, and other men who have sex with men (MSM) ≤26 years.

Methods: Data were obtained from 27 clinics participating in the STD Surveillance Network (SSuN). Read More

Asian Pac J Cancer Prev 2018 Nov 29;19(11):3039-3044. Epub 2018 Nov 29.

Pathology and Stem Cell Research Center, erman University of Medical Sciences, Kerman, Iran. Email:

Breast cancer is the first of the most important causes of the deaths of women in the world and in Iran. There are various causes and causes of this cancer, one of which has recently been described as a cause of breast cancer, is the human papillomavirus (HPV). The HPV is transmitted through sexual contact and skin lesions. Read More

Front Immunol 2018 12;9:2478. Epub 2018 Nov 12.

Department of Parasitology, Center of Research Excellence on Therapeutic Proteins and Antibody Engineering, Faculty of Medicine SIriraj Hospital, Mahidol University, Bangkok, Thailand.

Human papillomavirus (HPV) is a viral infection with skin-to-skin based transmission mode. HPV annually caused over 500,000 cancer cases including cervical, anogenital and oropharyngeal cancer among others. HPV vaccination has become a public-health concern, worldwide, to prevent the cases of HPV infections including precancerous lesions, cervical cancers, and genital warts especially in adolescent female and male population by launching national programs with international alliances. Read More

Int J Gynecol Pathol 2018 Nov 21. Epub 2018 Nov 21.

Departments of Pathology (S.I., A.K., W.G.M.) Dermatology (S.H.), Belfast Health and Social Care Trust Belfast Skin Clinic (P.M.) Centre for Medical Education, Queen's University (J.H.), Belfast Department of Pathology, Southmead Hospital, Bristol (K.M.) Department of Pathology, Antrim Area Hospital, Antrim, UK (J.J.).

Epidermolytic acanthoma is a rare benign lesion that most often presents as a solitary or multiple small papular lesions on the trunk, face, limbs or external male genitalia. Only a small number of cases have been reported occurring on the vulva and clinically and histologically they may mimic and be misdiagnosed as viral warts. We report 2 cases of multiple epidermolytic acanthomas localized to the vulva. Read More

J Surg Res 2018 Dec 11;232:629-634. Epub 2018 Aug 11.

Division of Colorectal Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin. Electronic address:

Background: Human papillomavirus is a common sexually transmitted infection that may affect the oropharynx, genitalia, or anus. Some strains of this virus may cause bulky growths around the anus known as giant anal condylomas. These can become large, disfiguring, and may cause bleeding, as well as difficulty with defecation and hygiene. Read More

Urologe A 2018 Dec;57(12):1499-1508

, Terpstig 55, 25980, Sylt OT Morsum, Deutschland.

Vaccination qualifies as the most effective medical procedure worldwide. Using the example of human papillomavirus(HPV)-associated benign and malignant diseases, the incidence, diagnostics, treatment, particularly however, the option of sustainable elimination of all these entities by achieving herd immunity by a gender balanced inoculation quota of 80% at the age of 9-17 years are shown. Read More

Acta Derm Venereol 2018 11 14. Epub 2018 Nov 14.

Department of Dermatology and Venereology, Skane University Hospital, SE-214 28 Malmö, Sweden. Department of Dermatology and Venereology, Skane University Hospital, SE-214 28 Malmö, Sweden.

Studies on risk factors for penile intraepithelial neoplasia have been small in size, have not distinguished penile intraepithelial neoplasia from invasive cancer, and have relied on self-reported information. This study investigated risk factors for penile intraepithelial neoplasia in a cohort of 580 penile intraepithelial neoplasia cases and 3,436 controls using information from 7 Swedish registers. Cases with penile intraepithelial neoplasia had increased odds ratios (ORs) for inflammatory skin diseases (14. Read More

PLoS One 2018 12;13(11):e0206726. Epub 2018 Nov 12.

Gonçalo Moniz Institute, Oswaldo Cruz Foundation, Salvador, Brazil.

Background: The World Health Organization has recommended the introduction of HPV vaccines into national immunization programme (NIP), but vaccination coverage remains low worldwide. We assessed the coverage and the parental acceptance of female and male HPV vaccination in Brazil after its introduction into the NIP.

Methods: We conducted a random-digit-dial survey of parents in seven major Brazilian cities from July-2015 to October-2016. Read More

Front Oncol 2018 26;8:422. Epub 2018 Oct 26.

School of Public Health, Texas A&M University, College Station, TX, United States.

People living with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) and, men who have sex with men (MSM) are disproportionately affected by genital warts and cancers caused by human papillomavirus (HPV). We assessed community-based HIV/AIDS service organizations' (ASOs) staff awareness, knowledge, attitudes, and beliefs about HPV and effective cancer prevention tools, namely HPV vaccination, Pap, and HPV tests. The potential engagement of ASO staff in future efforts to reduce the disproportionate burden of genital warts and HPV-related cancers among HIV-positive women and MSM was explored. Read More

Medicine (Baltimore) 2018 Oct;97(43):e12539

Department of Psychiatry, Chiayi Branch, Taichung Veterans General Hospital, Chiayi.

Depressive disorder is a severe mental disorder associated with functional and cognitive impairment. Numerous papers in the literature investigated associations between sexually transmitted infections (STIs) and psychiatric illnesses. However, the results of these studies are controversial. Read More

Sex Transm Infect 2018 Nov 8. Epub 2018 Nov 8.

Melbourne Sexual Health Centre, Alfred Health, Melbourne, Victoria, Australia

Objective: In mid-2017, the Victorian Government funded a free time-limited human papillomavirus (HPV) vaccination catch-up programme for gay and bisexual men who have sex with men (MSM) aged up to 26 years through sexual health clinics or other immunisation centres. We aimed to examine the uptake of the HPV vaccine among young MSM attending the Melbourne Sexual Health Centre (MSHC).

Methods: MSM aged ≤26 attending MSHC between 27 April 2017 and 31 December 2017 were included in the analysis. Read More

Medicine (Baltimore) 2018 Nov;97(45):e13201

Division of Infectious Diseases, Department of Internal Medicine.

Human papillomavirus (HPV) infection is associated with cancer and can be prevented through vaccination. Few studies from Taiwan have reported on HPV infection among human immunodeficiency virus (HIV)-infected subjects. The aim of this study was to examine the prevalence of HPV infection among men who have sex with men (MSM) with and without HIV infection in Taiwan, and explore the behavioral risk factors thereof. Read More

BMC Med Res Methodol 2018 Nov 6;18(1):125. Epub 2018 Nov 6.

UCL Centre for Clinical Research in Infection and Sexual Health, The Mortimer Market Centre, Institute for Global Health, University College London, London, WC1E 6JB, UK.

Background: Anogenital warts are the second most common sexually transmitted infection diagnosed in sexual health services in England. About 90% of genital warts are caused by human papillomavirus (HPV) types 6 or 11, and half of episodes diagnosed are recurrences. The best and most cost-effective treatment for patients with anogenital warts is unknown. Read More

Clin Colon Rectal Surg 2018 Nov 2;31(6):321-327. Epub 2018 Nov 2.

Division of Colon and Rectal Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri.

Human papillomavirus (HPV) infection is responsible for 4.3% of the global cancer burden. Since 2006, current HPV vaccines have reduced the prevalence of the virus in adolescent girls, reduced the prevalence of genital warts, and been proven to reduce the progression of anal intraepithelial neoplasia in men. Read More

Int J STD AIDS 2018 Nov 5:956462418796088. Epub 2018 Nov 5.

2 Center for Observational and Real-World Evidence, Merck & Co., Inc., Kenilworth, NJ, USA.

Genital warts (GW) are mucosal or skin lesions caused by sexual transmission of human papillomavirus (HPV). This study estimates the frequency of GW cases in physicians' clinics and physicians' usual practices of GW referral and diagnosis in Peru. Participants in this study were a convenience sample of 100 physicians in five specialties: primary care (17), gynecology (37), urology (10), dermatology (31), and infectious diseases (5). Read More

Zhonghua Zhong Liu Za Zhi 2018 Oct;40(10):724-728

Department of Cancer Epidemiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

Prophylactic HPV vaccine was a milestone in the prevention and control of HPV-related diseases, especially cervical cancer. The first HPV vaccine has been marketed in the world for more than 10 years. The follow-up study of HPV vaccine clinical trials further confirms the effectiveness and safety. Read More

J Infect Dis 2019 Feb;219(5):703-710

Instituto de Química, Departamento de Bioquímica, Universidade de São Paulo, Brazil.

Background: Genital wart (GW) incidence is high among men. The percentage and rate at which subsequent GW events occur are understudied. The purpose of this study was to describe the rate of subsequent GWs, associated human papillomavirus (HPV) types, and time to subsequent GW event among unvaccinated men. Read More

J Assoc Nurses AIDS Care 2018 Nov - Dec;29(6):942-948. Epub 2018 May 26.

We used a cross-sectional study in 2011 to estimate prevalence and risk behaviors for self-reported symptomatic sexually transmitted infections (STI) in rural settlers in Midwestern Brazil. There were 353 individuals recruited who had been living in the settlement for more than 6 months. The endpoint variable was having reported vaginal discharge, urethral discharge, genital ulcers, or anogenital warts in the previous 12 months. Read More

J Drugs Dermatol 2018 Oct;17(10):1100-1105

Background: Nitric oxide (NO), a free radical gas, is endogenously produced in human cells. In high concentration, NO neutralizes many disease-causing microbes. The topical investigational drug SB206 releases NO and has the potential to treat skin diseases caused by viruses. Read More

J Infect Dis 2019 Feb;219(5):682-684

Sexually Transmitted Infection Unit, Institut National de Santé Publique du Québec, Montréal, Canada.

SAGE Open Med Case Rep 2018 10;6:2050313X18802143. Epub 2018 Oct 10.

Division of Dermatology, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, AB, Canada.

Condyloma acuminata, also known as anogenital warts, represent a cutaneous infection caused by sexual transmission of the human papilloma virus. We present a case of overwhelming condyloma acuminata that was treated successfully without surgery using only topical imiquimod 3.75% cream. Read More

Clinics (Sao Paulo) 2018 10 11;73(suppl 1):e486s. Epub 2018 Oct 11.

Centro de Pesquisa Translacional em Oncologia, Instituto do Cancer do Estado de Sao Paulo (ICESP), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.

Human papillomavirus infection is associated with the development of malignant and benign neoplasms. Approximately 40 viral types can infect the anogenital mucosa and are categorized into high- and low-risk oncogenic human papillomavirus, depending on their association with the development of cervical carcinoma. High-risk human papillomavirus 16 and 18 are detected in 55% and 15% of all invasive cervical squamous cell carcinomas worldwide, respectively. Read More

Euro Surveill 2018 Oct;23(41)

Robinson Research Institute and Adelaide Medical School, University of Adelaide, North Adelaide, Australia.

Background: A National human papilloma virus (HPV) Vaccination Programme for the prevention of HPV infection and associated disease using the quadrivalent HPV vaccine (4vHPV) has been funded and implemented in Australia since 2007, initially for girls only and extended to boys in 2013, with uptake rates among the highest observed worldwide.

Aim: We report on the impact of this national programme on HPV prevalence and associated disease burden and estimate the potential impact of adopting a nonavalent HPV (9vHPV) vaccine.

Methods: We performed a non-systematic literature review of studies measuring the burden of HPV-associated disease and infection in Australia before and after introduction of HPV vaccination. Read More

Rev Med Brux 2018;39(4):352-358

Service de Maladies infectieuses et tropicales, CHU Ambroise Paré, Mons.

High-risk oncogenic HPVs (HR-HPV) are associated in men with pre-cancerous anal dysplasia, oropharyngeal, anal and penile cancer. Anogenital warts are induced by low-risk HPVs. These manifestations are increasing among men, and especially in some high-risk groups as men who have sex with men (MSM). Read More

Emerg Microbes Infect 2018 Sep 26;7(1):160. Epub 2018 Sep 26.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Life Sciences, Xiamen University, 361102, Xiamen, China.

Human papillomavirus (HPV) is the causative agent in genital warts and nearly all cervical, anogenital, and oropharyngeal cancers. Nine HPV types (6, 11, 16, 18, 31, 33, 45, 52, and 58) are associated with about 90% of cervical cancers and 90% of genital warts. HPV neutralization by vaccine-elicited neutralizing antibodies can block viral infection and prevent HPV-associated diseases. Read More

Int J Colorectal Dis 2019 Jan 22;34(1):47-54. Epub 2018 Sep 22.

Department of General and Colorectal Surgery, Kaiser Permanente San Diego, 4405 Vandever Avenue, Fourth Floor, San Diego, CA, 92120, USA.

Purpose: To determine the impact of expectant management surveillance for patients at risk for squamous cell carcinoma of the anus (SCCA).

Methods: Adult patients at risk for anal cancer, specifically those with human immunodeficiency virus (HIV) or known human papilloma virus (HPV) infections (anal dysplasia, anogenital warts, cervical dysplasia, or cervical cancer), underwent expectant management surveillance with targeted therapy of only grossly abnormal or symptomatic anoderm lesions. A retrospective analysis investigated the SCCA incidence in these surveilled populations and in the general population patients without known HIV or HPV infection. Read More