4,462 results match your criteria Warts Genital


The quadrivalent HPV vaccine is protective against genital warts: a meta-analysis.

BMC Public Health 2020 May 28;20(1):691. Epub 2020 May 28.

Department of Public Health, Faculty of Medicine, University of Szeged, Dóm tér 10, Szeged, 6720, Hungary.

Background: The quadrivalent human papillomavirus (HPV) vaccine has been assumed to give protection against genital warts (GW) as well as cervical cancer. Our main question was whether HPV vaccine has any effects on the prevention of GW reported in randomised controlled clinical trials (RCTs) and time-trend analyses.

Methods: This meta-analysis was performed according to the PRISMA guidelines using the PICO format. Read More

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http://dx.doi.org/10.1186/s12889-020-08753-yDOI Listing

Could the human papillomavirus vaccine prevent recurrence of ano-genital warts?: a systematic review and meta-analysis.

Int J STD AIDS 2020 May 21:956462420920142. Epub 2020 May 21.

Department of Dermatology and Venereology, Hospital de Baza, Granada, Spain.

Human papillomavirus (HPV) is the most prevalent sexually transmitted infection worldwide and ano-genital warts (AGWs) are highly infectious. This virus is transmitted through sexual, anal, or oral contact as well as skin-to-skin contacts. Treatment for this condition has significant morbidity and it can be frustrating in certain cases. Read More

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http://dx.doi.org/10.1177/0956462420920142DOI Listing

Atypical presentation of genital molluscum contagiosum mimicking genital warts.

Int J STD AIDS 2020 May 21:956462420920410. Epub 2020 May 21.

Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

A man in his 20s with a history of unprotected sex with a commercial sex worker three months before presented with a solitary slowly-growing, well-defined, non-tender, oval, verrucous lesion on the mucosal aspect of his prepuce. Dermoscopy revealed a polylobular, pinkish-white, amorphous structure in the centre with a surrounding crown of vessels that did not cross the centre of the lobules, and histopathology showed keratinocytes containing intracytoplasmic faintly granular eosinophilic inclusions and peripherally-pushed nuclei. A diagnosis of agminated genital molluscum contagiosum was reached on the basis of the above findings. Read More

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http://dx.doi.org/10.1177/0956462420920410DOI Listing

Self-efficacy and HPV Vaccine Attitudes Mediate the Relationship Between Social Norms and Intentions to Receive the HPV Vaccine Among College Students.

J Community Health 2020 May 16. Epub 2020 May 16.

Department of Psychology, Purdue School of Science, Indiana University-Purdue University Indianapolis, Indianapolis, IN, 46202, USA.

Human papillomavirus (HPV) has been linked to genital warts and multiple cancers affecting both men and women. Despite college students' high risk for HPV, their vaccination rates remain suboptimal. The current observational study examined the relationship between social norms and HPV vaccine intentions and potential mechanisms underlying this relationship among undergraduates. Read More

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http://dx.doi.org/10.1007/s10900-020-00837-5DOI Listing

HPV condylomatosis region treated with multiple sessions of MAL-PDT: a case report.

Photodiagnosis Photodyn Ther 2020 May 7:101812. Epub 2020 May 7.

Sao Carlos Institute of Physics, University of Sao Paulo, Brazil. Electronic address:

Condyloma or genital warts affect the tissues of the genital area due to infections induced by Human papillomavirus. There are some topical therapies indicated for condyloma lesions treatment but all of them present a high rate of recurrence. Photodynamic Therapy is proving to be an interesting strategy for treating these lesions, capable also to treat virus-infected cells on subclinical lesions. Read More

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http://dx.doi.org/10.1016/j.pdpdt.2020.101812DOI Listing

Non-participation in cervical cancer screening according to health, lifestyle and sexual behavior: A population-based study of nearly 15,000 Danish women aged 23-45 years.

Prev Med 2020 May 6;137:106119. Epub 2020 May 6.

Unit of Virus, Lifestyle, and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark. Electronic address:

High participation in cervical cancer screening is essential for an effective screening program. In this population-based study, we investigated associations between general health, lifestyle and sexual behavior, and non-participation in cervical cancer screening in Denmark. During 2011-2012, a random sample of women aged 18-45 years from the general female population were invited to participate in a survey regarding health, lifestyle and sexual habits. Read More

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http://dx.doi.org/10.1016/j.ypmed.2020.106119DOI Listing

Burden of HPV related anogenital diseases in young women in Germany - an analysis of German statutory health insurance claims data from 2012 to 2017.

BMC Infect Dis 2020 Apr 22;20(1):297. Epub 2020 Apr 22.

Department of Obstetrics and Gynecology, University Hospital of Duesseldorf, Duesseldorf, Germany.

Background: Most individuals are infected with human papillomavirus (HPV) at least once in their lifetime. Infections with low-risk types can cause genital warts, whereas high-risk types can cause malignant tumors. The aim of this study was to determine the burden of anogenital diseases potentially related to HPV in young women based on German statutory health insurance claims data. Read More

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http://dx.doi.org/10.1186/s12879-020-05002-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178589PMC

The Prevalence of Human Immunodeficiency Virus Infection in Patients with Sexually Transmitted Diseases.

Adv Biomed Res 2020 16;9:11. Epub 2020 Mar 16.

Brucellosis Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.

Background: Human immunodeficiency virus (HIV) transmission pattern in Iran has been changed from injection drug to sexual contact. Lack of accurate assessment of HIV in people with sexually transmitted diseases (STDs) in Iran prompted us to conduct this study to determine the frequency of HIV infection in these patients.

Materials And Methods: In this cross-sectional study which conducted in 2016-2017, overall, 190 patients with STDs referring to two hospitals of Hamadan were enrolled in the study. Read More

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http://dx.doi.org/10.4103/abr.abr_233_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147514PMC

Anogenital Papular Lesions in Children Five Year Old and Younger: Gender Differences.

Med Arch 2020 Feb;74(1):28-33

Department of Dermatology and Venereology, the Royal Medical Services (RMS), Amman, Jordan.

Introduction: Anogenital area is a small compartment in the human body. Recognition of various dermatological conditions affecting this area in children is essential for any physician involved in pediatric examination and evaluation.

Aim: To assess the nature, diagnoses, and gender differences of Anogenital lesions in pediatric patients presented to Royal Medical Services (RMS) general dermatology clinics, who were five year old and younger. Read More

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http://dx.doi.org/10.5455/medarh.2020.74.28-33DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164741PMC
February 2020

Scientific evidence supporting recommendations on the use of the 9-valent HPV vaccine in a 2-dose vaccine schedule in Australia.

Commun Dis Intell (2018) 2020 Apr 15;44. Epub 2020 Apr 15.

Vaccinology and Immunology Research Trials Unit, Women's and Children's Hospital and Robinson Research Institute and Adelaide Medical School, University of Adelaide, North Adelaide, South Australia.

The Australian Technical Advisory Group on Immunisation (ATAGI) updated recommendations on the use of human papillomavirus (HPV) vaccines in the Australian Immunisation Handbook in 2018, regarding the use of the recently available 9-valent (9vHPV) vaccine, Gardasil 9, and a 2-dose schedule for young adolescents for HPV vaccines. This report provides an overview of the relevant scientific evidence that underpinned these updated recommendations. The 9vHPV vaccine includes 5 HPV types (HPV 31, 33, 45, 52 and 58) additional to the 4 that are also covered by the 4vHPV (Gardasil) vaccine (HPV 6,11,16,18). Read More

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http://dx.doi.org/10.33321/cdi.2020.44.33DOI Listing

Are genital examinations necessary for STI screening for female sex workers? An audit of decriminalized and regulated sex workers in Melbourne, Australia.

PLoS One 2020 16;15(4):e0231547. Epub 2020 Apr 16.

Melbourne Sexual Health Centre, Alfred Health, Melbourne, Victoria, Australia.

Background: The Victorian legislation prohibits sex workers from working when they have visible anogenital herpes or warts. The aim of this study was to determine the proportion of asymptomatic female sex workers (FSW) diagnosed with anogenital herpes or warts by genital examination.

Methods: We analysed all computerised medical records of consultations with FSW at the Melbourne Sexual Health Centre (MSHC) in 2018. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0231547PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161967PMC

CO laser treatment for plantar warts in children: A case series.

Dermatol Ther 2020 Apr 14:e13414. Epub 2020 Apr 14.

Molecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Several types of human papillomaviruses induce warts. Warts are one of the most common infections in childhood with a reported prevalence of up to 20%. Warts are divided clinically into genital and nongenital forms. Read More

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http://dx.doi.org/10.1111/dth.13414DOI Listing

Assessing Gammapapillomavirus infections of mucosal epithelia with two broad-spectrum PCR protocols.

BMC Infect Dis 2020 Apr 7;20(1):274. Epub 2020 Apr 7.

Grupo Virología Humana, Instituto de Biología Molecular y Celular de Rosario (CONICET), Suipacha 590, 2000, Rosario, Argentina.

Background: Human papillomaviruses (HPVs) have been divided into mucosal and cutaneous types according to their primary epithelial tissue tropism. However, recent studies showed the presence of several cutaneous types in mucosal lesions and healthy mucosa from different anatomical sites.

Methods: Here, the HPV prevalence and type-specific distribution were assessed in a variety of mucosal samples from 435 individuals using a combination of two established broad-spectrum primer systems: Gamma-PV PCR and CUT PCR. Read More

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http://dx.doi.org/10.1186/s12879-020-4893-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140492PMC

Awareness of oral and genital human papillomavirus (HPV) infection in young adolescents prior to gender-neutral vaccination.

BMJ Sex Reprod Health 2020 Apr 2. Epub 2020 Apr 2.

Human Sciences Research Centre, University of Derby, Derby, UK.

Introduction: Oral human papillomavirus (HPV) and oropharyngeal cancer prevalence are increasing, particularly in men. Raising greater awareness of male HPV disease is perceived as an important intervention strategy. This study investigated the effectiveness of HPV education on adolescents' perception of HPV disease and the impact of HPV vaccination on their sexual health. Read More

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http://dx.doi.org/10.1136/bmjsrh-2019-200410DOI Listing

Prevalence of Cervico-vaginal High-risk HPV Types and Other Sexually Transmitted Pathogens in Anogenital Warts Patients.

Anticancer Res 2020 Apr;40(4):2219-2223

1 Department of Dermatology and Venereology, National and Kapodistrian University of Athens, "Andreas Sygros" Hospital for Skin and Venereal Diseases, Athens, Greece.

Aim: To investigate the prevalence of cervico-vaginal co-infection with high-risk (HR) HPV types and other sexually transmitted pathogens (STPs) in women with anogenital warts (AGWs).

Patients And Methods: In this cross-sectional study, cervico-vaginal smears of women with AGWs were examined with real-time polymerase chain reaction for the presence of HR-HPV types and common STPs. Women with recent cervical HPV infection and general population were used for comparisons. Read More

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http://dx.doi.org/10.21873/anticanres.14183DOI Listing

Influence of Gender and Undergraduate Course on the Knowledge about HPV and HPV Vaccine, and Vaccination Rate among Students of a Public University.

Rev Bras Ginecol Obstet 2020 Feb 30;42(2):96-105. Epub 2020 Mar 30.

Department of Obstetrics and Gynecology, Medical School, Universidade Estadual de Campinas, Campinas, SP, Brazil.

Objective:  To evaluate the knowledge related to human papillomavirus (HPV) infection and the rate of HPV vaccination among undergraduate freshmen and senior students of medicine, pharmacy, speech therapy, nursing and physical education in a Brazilian university.

Methods:  A questionnaire concerning sociodemographic aspects, sexual background, and knowledge about HPV and its vaccine was filled out by 492 students. Three months later, a second questionnaire, concerning the new rate of vaccination, was applied to 233 students. Read More

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http://dx.doi.org/10.1055/s-0040-1701466DOI Listing
February 2020

HPV genotypic spectrum in Jilin province, China, where non-vaccine-covered HPV53 and 51 are prevalent, exhibits a bimodal age-specific pattern.

PLoS One 2020 24;15(3):e0230640. Epub 2020 Mar 24.

Key Laboratory of Organ Regeneration & Transplantation of the Ministry of Education, Genetic Diagnosis Center, The First Hospital of Jilin University, Changchun, China.

Background: Human papillomavirus (HPV), the most common sexually transmitted disease, is involved in a series of other diseases. The persistent infection of high-risk HPVs (HR-HPVs) is considered to be the causative agent of cervical cancer, and it is related to noncervical cancers. The present study aims to estimate the HPV prevalence and genotype distribution in Jilin province, China, to guide HPV-related cervical cancer screening and HPV vaccination. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0230640PLOS

Condylomata acuminata: A retrospective analysis on clinical characteristics and treatment options.

Heliyon 2020 Mar 11;6(3):e03547. Epub 2020 Mar 11.

Department of Dermatology and Allergy, University Hospital of Munich (LMU), Munich, Germany.

Background: Anogenital HPV is the most frequent sexually transmitted disease (STD) worldwide. There is no obligation to officially register HPV infections in Germany and thus the epidemiology of condylomata acuminata (CA) is not well characterized.

Objectives: To provide a better understanding of the epidemiology of CA and outline the treatment options that are available to patients with this disease. Read More

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http://dx.doi.org/10.1016/j.heliyon.2020.e03547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068618PMC

Increased risk of dementia in patients with genital warts: A nationwide cohort study in Taiwan.

J Dermatol 2020 May 18;47(5):503-511. Epub 2020 Mar 18.

Department of Psychiatry, Tri-Service General Hospital, School of Medicine, Taipei, Taiwan.

Genital warts are a common sexually transmitted disease caused by human papillomavirus (HPV) infections. The prevalence of dementia is 4-8% in those aged 65 years or older in Taiwanese community studies, with a high social and economic burden for patients, family caregivers, the community and society. Previous studies have shown that viral infections such as herpes simplex and herpes zoster were associated with dementia. Read More

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http://dx.doi.org/10.1111/1346-8138.15277DOI Listing

Pan-urethral condylomata acuminata - A primary treatment recommendation based on our experience.

Urol Case Rep 2020 Jul 29;31:101149. Epub 2020 Feb 29.

Department of Urology, Austin Health, Heidelberg, VIC, Australia.

We present a case of a 28 year old man presenting with obstructive urinary tract symptoms and cystoscopic findings of pan-urethral, occlusive condylomata acuminata (urethral genital warts). We describe the in rooms administration process of 5-fluorouracil over an 8 week period with follow up cystoscopy results. Urine flow rates improved early in the treatment course from a maximum flow of 7ml/s to 19ml/s and a post void residual improvement from 311ml to 160ml. Read More

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http://dx.doi.org/10.1016/j.eucr.2020.101149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056647PMC

Transcriptome analysis of HPV-induced warts and healthy skin in humans.

BMC Med Genomics 2020 03 9;13(1):35. Epub 2020 Mar 9.

Department of Internal Medicine, Jordan University of Science and Technology, Irbid, 22110, Jordan.

Background: The human papillomaviruses (HPV) are a group of viruses that, depending on the strain, can cause cancer or the formation of benign growths known as warts. Scarce information exists with regard to the genetic nature of non-genital cutaneous warts induced by the human papillomavirus (HPV).

Methods: The main purpose of this study is to investigate the differences between the gene expression profiles of common warts and healthy skin in HPV-positive individuals by RNA sequencing on the Illumina HiSeq 2500. Read More

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http://dx.doi.org/10.1186/s12920-020-0700-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063766PMC

Aspects of Langerhans cells and TNF-α in the cutaneous immunity of anogenital warts.

An Bras Dermatol 2020 Mar - Apr;95(2):144-149. Epub 2020 Feb 12.

Pathology Laboratory, Santa Casa de Misericórdia de São Paulo, Vila Buarque, SP, Brazil.

Background: Anogenital warts are the leading sexually transmitted infection in patients seeking care at specialized clinics. They may display a vast array of forms, according to the interaction of the virus with the host's immunity. Cellular immunity is the epithelium's main form of defense against the virus, involving an active participation of the Langerhans cells and pro-inflammatory cytokines such as TNF-α. Read More

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http://dx.doi.org/10.1016/j.abd.2019.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175043PMC

The Use of Both Therapeutic and Prophylactic Vaccines in the Therapy of Papillomavirus Disease.

Front Immunol 2020 18;11:188. Epub 2020 Feb 18.

Department of Biology and Biotechnology "C. Darwin," Sapienza University, Rome, Italy.

Human papillomavirus (HPV) is the most common sexually transmitted virus. The high-risk HPV types (i.e. Read More

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http://dx.doi.org/10.3389/fimmu.2020.00188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040023PMC
February 2020

Prevention of Human Papillomavirus Infection. Beyond Cervical Cancer: A Brief Review.

Acta Med Port 2020 Mar 2;33(3):198-201. Epub 2020 Mar 2.

Department of Gynaecology. Hospital and University Centre of Coimbra. Coimbra. Department of Gynaecology. Faculty of Medicine. University of Coimbra. Coimbra. Portugal.

Introduction: Human papillomavirus is responsible for almost all cases of cervical cancer, an important portion of anogenital and oropharyngeal invasive and preinvasive lesions, as well as genital warts (condyloma acuminatum) and recurrent respiratory papillomatosis. Currently, three prophylactic vaccines against high-risk Human papillomavirus are commercialized in many countries worldwide.

Methods: To this non-systematic review the authors searched in MEDLINE/PubMed for systematic reviews, meta-analysis and randomized controlled trials, published in the last six years, using the terms "HPV", "non-cervical cancer" and "vaccine". Read More

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http://dx.doi.org/10.20344/amp.12259DOI Listing

Cure of condyloma acuminata covering the glans penis using aminolevulinic acid/photodynamic therapy.

Photodiagnosis Photodyn Ther 2020 Feb 26:101658. Epub 2020 Feb 26.

The First Affiliated Hospital of Zhengzhou University, China.

Condyloma acuminata are a type of verrucous hyperplasia in the genital and perianal areas caused by human papilloma virus (HPV) infection. Traditional treatment methods for condyloma acuminata, such as topical medications, carbon dioxide (CO) laser, cryotherapy, and surgical excision, can be effective at removing warts, however, they do not eliminate subclinical and latent HPV infection, resulting in a high recurrence rate and even leaving trauma and scars. We report a case of condyloma acuminata covering the glans penis, considering our patient had a singular, large lesion, thus, to reduce the risk of recurrence and minimize the trauma caused by treatment, we chose ALA/photodynamic therapy (ALA-PDT). Read More

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http://dx.doi.org/10.1016/j.pdpdt.2020.101658DOI Listing
February 2020

[HPV vaccination with quadrivalent or nonavalent vaccine: an opportunity to eliminate genital warts as well].

Ned Tijdschr Geneeskd 2020 Jan 9;164. Epub 2020 Jan 9.

Amsterdam UMC, locatie AMC, afd. Huisartsgeneeskunde, Amsterdam.

The impact of genital warts on psychological, social and sexual wellbeing is often overlooked, as is the magnitude of the problem. In 2017, the number of consultations in primary care in the Netherlands was 42,000. Real-world evidence shows compelling and impressive results regarding the reduction of genital warts in other countries. Read More

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January 2020

[Continue to use the bivalent HPV vaccine; bivalent vaccine more effective than expected].

Ned Tijdschr Geneeskd 2020 Jan 9;164. Epub 2020 Jan 9.

UMCG-Rijksuniversiteit Groningen, afd. Medische Microbiologie en Infectieppreventie,Groningen.

It is becoming clear that there are significant differences between the two principal human papillomavirus (HPV) vaccines, namely the bivalent vaccine and the quadrivalent vaccine. Both vaccines contain HPV16 and HPV18, together responsible for approximately 73% of cases of cervical cancer. The quadrivalent vaccine also contains HPV6 and HPV11, thus protecting against genital warts. Read More

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January 2020

Health students' knowledge of sexually transmitted infections and risky behaviors before participation to the health promotion program.

Med Mal Infect 2020 Jun 14;50(4):368-371. Epub 2020 Feb 14.

Service d'infectiologie, CHU de Saint-Étienne, Saint-Étienne, France; Institut de prévention en santé globale Présage, université de Lyon, UJM, Lyon, France. Electronic address:

Objectives: We aimed to evaluate knowledge of health students (HS) enrolled in a health promotion program about sexually transmitted infections (STIs) and the frequency of risky behaviors.

Methods: HS answered two anonymous questionnaires, a mandatory one about knowledge of STIs and STI prevention and an optional one about behaviors.

Results: Two-hundred and sixteen HS answered the first questionnaire and 183 answered the second one. Read More

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http://dx.doi.org/10.1016/j.medmal.2020.01.015DOI Listing

Topical application of temperature-sensitive caerin 1.1 and 1.9 gel inhibits TC-1 tumor growth in mice.

Am J Transl Res 2020 15;12(1):191-202. Epub 2020 Jan 15.

The First Affiliated Hospital/Clinical Medical School, Department of Nuclear Medicine, Guangdong Pharmaceutical University Guangzhou 510080, Guangdong, China.

Genital warts, which are one of the most common sexually transmitted diseases (STDs), result from persistent infection with human papillomavirus (HPV), especially subtypes 6 or 11. Topical application of 5% imiquimod cream is currently recommended as a first-line treatment choice for genital warts, but the clearance and patient compliance rates remain less than sufficient. In the current study, we developed a temperature-sensitive gel that contains the host-defense peptides caerin 1. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013226PMC
January 2020

Association of Atopic Dermatitis With Bacterial, Fungal, Viral, and Sexually Transmitted Skin Infections.

Dermatitis 2020 Mar/Apr;31(2):157-164

Departments of Dermatology, Preventive Medicine and Medical Social Sciences, Northwestern University Feinberg School of Medicine.

Background: Atopic dermatitis (AD) is associated with altered skin barrier, microbiome, and immune dysregulation that may increase risk of skin infections.

Objective: The aim of the study was to determine whether AD is associated with skin infections and related outcomes.

Methods: Data from the 2006 to 2012 National Emergency Department Sample were analyzed, including an approximately 20% sample of all US emergency department (ED) visits (N = 198,102,435 adults or children). Read More

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http://dx.doi.org/10.1097/DER.0000000000000526DOI Listing
February 2020

Assessment of Knowledge, Attitudes, and Propensity towards HPV Vaccine of Young Adult Students in Italy.

Vaccines (Basel) 2020 Feb 7;8(1). Epub 2020 Feb 7.

IRCCS San Martino Hospital, 16132 Genoa, Italy.

Background: Human Papillomavirus (HPV) is a common sexually transmitted infection (STI), representing the main cause of genital warts and cervical cancer. This cross-sectional study evaluated knowledge and attitudes about HPV infection, related diseases, and prevention and propensity towards HPV vaccine among undergraduate students.

Methods: An online and written survey about HPV and its prevention, targeted to young adults of both genders, was addressed to students attending health sciences and other schools at Universities of Genoa and Bari. Read More

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http://dx.doi.org/10.3390/vaccines8010074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157590PMC
February 2020

Successful Therapy with 5-ALA Photodynamic Therapy for Bowen's Disease in a Single Lobulated Nodule Mimicking Genital Warts.

Indian J Dermatol 2020 Jan-Feb;65(1):78-79

Dermatology Department of West China Hospital of Sichuan University, Chengdu, China. E-mail:

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http://dx.doi.org/10.4103/ijd.IJD_484_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986120PMC
February 2020

The Lady Garden Club: supporting women with vulval conditions and their partners.

J Eur Acad Dermatol Venereol 2020 Feb 6. Epub 2020 Feb 6.

Chelsea & Westminster Hospital NHS Foundation Trust, London, UK.

Background: Vulval conditions have been shown to have a significant impact on patients' quality of life and can affect their relationships. The Lady Garden Club (LGC) is peer support group that was set up by patients with vulval conditions and is supported by the vulval clinic physicians at Chelsea & Westminster Hospital.

Objectives: Our aim was to assess the efficacy of this peer support group and the physician contribution to it. Read More

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http://dx.doi.org/10.1111/jdv.16276DOI Listing
February 2020

Successful treatment of refractory genital warts using 0.5% podophyllotoxin-loaded nanostructured lipid carriers.

Dermatol Ther 2020 Mar 11;33(2):e13245. Epub 2020 Feb 11.

Department of Dermatology and Venereology, Nanfang Hospital, Southern Medical University, Guangzhou, China.

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http://dx.doi.org/10.1111/dth.13245DOI Listing

Enhanced Glycogen Metabolism Supports the Survival and Proliferation of HPV-Infected Keratinocytes in Condylomata Acuminata.

J Invest Dermatol 2020 Jan 29. Epub 2020 Jan 29.

Department of Dermatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address:

Condylomata acuminata (CA) is caused by human papillomavirus (HPV) infections of keratinocytes and is a common sexually transmitted disease. The main clinical feature and risk of CA is the high recurrence of genital warts formed by infected keratinocytes. Metabolic reprogramming of most types of mammalian cells including keratinocytes can provide energy and intermediates essential for their survival. Read More

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http://dx.doi.org/10.1016/j.jid.2020.01.010DOI Listing
January 2020

Skin Infections and Outpatient Burn Management: Fungal and Viral Skin Infections.

FP Essent 2020 Feb;489:16-20

Maine-Dartmouth Family Medicine Residency, 15 East Chestnut St, Augusta, ME 04330.

Fungal and viral skin infections are common and typically are managed by family physicians. The fungal skin infections commonly seen in family practice include the various forms of tinea: tinea corporis, tinea gladiatorum, tinea cruris, tinea pedis, tinea capitis, and tinea unguium (eg, onychomycosis). Common viral skin infections include herpes simplex virus infection, herpes zoster, cutaneous and genital warts, and molluscum contagiosum. Read More

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February 2020

Estimating nationwide cases of sexually transmitted diseases in 2015 from sentinel surveillance data in Japan.

BMC Infect Dis 2020 Jan 28;20(1):77. Epub 2020 Jan 28.

Department of Medical Statistics, Toho University, Tokyo, Japan.

Background: The rates of newly diagnosed cases of sexually transmitted diseases, including genital chlamydial infection and gonorrhea, are important for prevention and control of these diseases. However, nationwide rates are not reported in Japan.

Methods: We used the number of cases of sexually transmitted diseases reported by nationwide sentinel surveillance in 2015, together with the number of all disease outpatients in September 2014 at all medical institutions, drawn from the Survey of Medical Institutions of Japan. Read More

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http://dx.doi.org/10.1186/s12879-020-4801-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986098PMC
January 2020

Knowledge, information needs and behavior regarding HIV and sexually transmitted infections among migrants from sub-Saharan Africa living in Germany: Results of a participatory health research survey.

PLoS One 2020 27;15(1):e0227178. Epub 2020 Jan 27.

Robert Koch Institute, Department for Infectious Disease Epidemiology, Unit for HIV/AIDS, STI and Blood-borne Infections, Berlin, Germany.

Background: A total of 3,419 new HIV diagnoses were reported in Germany in 2016, with migrants from sub-Saharan Africa (misSA) accounting for 14.1%. To understand the driving factors behind the epidemiological situation, we conducted a quantitative cross-sectional survey on knowledge, attitudes, behavior, and practices regarding HIV and sexually transmitted infections (STIs) among misSA living in six German cities utilizing participatory health research. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0227178PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984683PMC

Human papillomavirus vaccination and prevention of intraepithelial neoplasia and penile cancer: review article.

Curr Opin Urol 2020 Mar;30(2):208-212

Uro-Oncology Department, Cancer Institute of Sao Paulo, Sao Paulo, Brazil.

Purpose Of Review: The objective of the current article is to promote a literature revision of the relationship between the prevention of intraepithelial neoplasms (PeIN) and invasive penile cancer, and human papillomavirus (HPV) vaccination, aiming to enumerate the pros and cons of immunization.

Recent Findings: The immunization against the HPV is sufficiently safe and many countries have incorporated the vaccine to their immunization calendar. Compared with men, the sampling size and the evidence quality of scientific researches among the female population are more robust. Read More

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http://dx.doi.org/10.1097/MOU.0000000000000730DOI Listing

Coexistence of Anogenital Psoriasis and Genital Warts - Is There an Optimal Treatment?

Acta Dermatovenerol Croat 2019 Dec;27(4):270-272

Assoc. Prof. Suzana Ljubojević Hadžavdić, MD, PhD, Department of Dermatology and Venereology, Zagreb University Hospital Center, University of Zagreb School of Medicine, Šalata 4, 10000 Zagreb, Croatia;

The prevalence of psoriasis is 2% of the world's population (1). Inverse psoriasis is characterized by the development of erythematous shiny plaques at intertriginous areas of the body. The prevalence of only anogenital involvement appears to be low, but involvement of the anogenital area together with other areas is found in up to 45% of patients with psoriasis (2). Read More

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December 2019

Clinical Efficacy of Combination Therapy with Podophyllotoxin and Liquid Nitrogen Cryotherapy in the Treatment of Genital Warts in Men.

Acta Dermatovenerol Croat 2019 Dec;27(4):250-259

Prof. Zoran Golušin, MD, PhD, University of Novi Sad, Faculty of Medicine, Hajduk Veljkova 3, 21000 Novi Sad, Serbia;

High prevalence, peculiar etiopathogenesis, and ineffective therapies have contributed to the fact that genital warts are one of the most challenging issues in modern medicine. This prospective study was aimed at determining the clinical efficacy of combination therapy with 0.5% podophyllotoxin solution and liquid nitrogen cryotherapy in the local treatment of genital warts in men. Read More

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December 2019

Intralesional Candida antigen versus intralesional tuberculin in the treatment of recalcitrant genital warts: A comparative study.

J Am Acad Dermatol 2020 Jun 7;82(6):1512-1514. Epub 2020 Jan 7.

Dermatology, Venereology and Andrology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

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http://dx.doi.org/10.1016/j.jaad.2019.12.050DOI Listing
June 2020
4.449 Impact Factor

The impact of HPV multi-cohort vaccination: Real-world evidence of faster control of HPV-related morbidity.

Vaccine 2020 Feb 6;38(6):1345-1351. Epub 2020 Jan 6.

HPV-related Epidemiological Research Unit, Department of Research, Cancer Registry of Norway, Oslo University Hospital, P.O. Box 5313 Majorstuen, N-0304 Oslo, Norway. Electronic address:

Background: In 2009, both Norway and Denmark initiated routine quadrivalent human papillomavirus vaccination (qHPV) for 12-year-old girls; however, Denmark also introduced free-of-charge multi-cohort vaccination for older age groups in 2008. We aim to describe trends in genital warts (GWs) incidence rates (IRs) among men and women and qHPV vaccine coverage among women in Norway and Denmark in 2006-2015.

Methods: We linked multiple national health registries in Norway and Denmark via national personal identifiers to access data on GWs incidence and qHPV vaccination among women and men aged 12-35 years residing in Norway and Denmark in 2006-2015. Read More

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http://dx.doi.org/10.1016/j.vaccine.2019.12.016DOI Listing
February 2020

Tuberculous Uveitis, Erythema Induratum, and Persistent Genital Warts in a Female Patient: A Rare Case Report.

Adv Biomed Res 2019 27;8:70. Epub 2019 Nov 27.

Psoriasis Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.

Uveitis and erythema induratum are two uncommon extrapulmonary manifestations of tuberculosis (TB). In most circumstances, we cannot isolate mycobacterium from those sites, so diagnosis is difficult. In the presented case, panuveitis, erythema induratum, and persistent anogenital warts were found concurrently in a 19-year-old girl who had a history of pulmonary TB 10 years ago. Read More

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http://dx.doi.org/10.4103/abr.abr_154_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909546PMC
November 2019

Prevalence of N. gonorrhoeae, C. trachomatis, M. genitalium, M. hominis and Ureaplasma spp. in the anus and urine among Japanese HIV-infected men who have sex with men.

J Infect Chemother 2020 Apr 25;26(4):403-406. Epub 2019 Dec 25.

Department of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Science, 13-1, Takaramachi, Kanazawa, Ishikawa, 920-8641, Japan.

The present study investigated the prevalence of Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium, M. hominis, and Ureaplasma spp. (biovars 1 and 2) in Japanese HIV-positive men who have sex with men (MSM). Read More

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http://dx.doi.org/10.1016/j.jiac.2019.12.007DOI Listing

Virus-like Particle-Based L2 Vaccines against HPVs: Where Are We Today?

Viruses 2019 Dec 23;12(1). Epub 2019 Dec 23.

Department of Biological Sciences, Michigan Technological University, Houghton, MI 49931, USA.

Human papillomaviruses (HPVs) are the most common sexually transmitted infections worldwide. Ninety percent of infected individuals clear the infection within two years; however, in the remaining 10% of infected individuals, the infection(s) persists and ultimately leads to cancers (anogenital cancers and head and neck cancers) and genital warts. Fortunately, three prophylactic vaccines have been approved to protect against HPV infections. Read More

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http://dx.doi.org/10.3390/v12010018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019592PMC
December 2019

The role of human papilloma virus test in men: First exhaustive review of literature.

Actas Urol Esp 2020 03 23;44(2):86-93. Epub 2019 Dec 23.

Departamento de Urología, Fundació Puigvert, Universitat Autònoma de Barcelona, Barcelona, España.

Human papilloma virus (HPV) infection is the most common sexually transmitted infection worldwide. There is a high detection rate in sexually active young people but the risk, in males, persists over years. Currently, the American Center for Disease Control and Prevention does not recommend the evaluation of men for HPV and, the extant bibliography, backs up this stance for several reasons. Read More

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http://dx.doi.org/10.1016/j.acuro.2019.08.010DOI Listing

[Prevalence and management of condylomas in consulting population in Chile: "DIACON study"].

Rev Chilena Infectol 2019 Jun;36(3):283-291

Unidad de Investigación Clínica Alemana, Facultad de Medicina, Universidad Finis Terrae, Chile.

Introduction: Condylomas or genital warts (GW) are the most frequently diagnosed sexually transmitted infection (STI) in STI centers in Chile, but there are no population statistics available.

Objectives: To describe the prevalence of GW in patients from 18-60 years of age who attend outpatient dermatology, gynecology and urology practice; the demographic characteristics of the patients and the diagnostic and treatment tools.

Methods: A sample of Chilean specialists stratified by region, population and gender of patients was provided with a logbook and answered a questionnaire. Read More

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http://dx.doi.org/10.4067/S0716-10182019000300283DOI Listing

HPV vaccines: alternative dosage schedules.

Authors:
Margaret Stanley

Expert Rev Vaccines 2019 12 26;18(12):1309-1316. Epub 2019 Dec 26.

Department of Pathology, University of Cambridge, Cambridge, UK.

: The randomized control trials (RCTs) that resulted in licensure of HPV VLP vaccines used a traditional prime, prime-boost schedule for a subunit protein vaccine. These vaccines delivered predominantly to 9-14-year-old females with this schedule have been shown to be highly effective against vaccine HPV-type disease (CIN and genital warts) and infection. A two-dose prime-boost schedule is immunologically non-inferior to 3 doses in 9-14-year-olds and is currently widely adopted. Read More

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http://dx.doi.org/10.1080/14760584.2019.1704261DOI Listing
December 2019

Efficacy and Tolerability of Topical Polyphenon E in Multiple "Seborrheic Keratosis-Like" Lesions of the Groin in an Immunocompetent 26-Year-Old Man.

Case Rep Dermatol 2019 Sep-Dec;11(3):310-316. Epub 2019 Nov 7.

Medical Department Cantabria Labs Difa Cooper, Caronno Pertusella, Italy.

Polyphenon E 10%, a green tea extract containing epigallocatechin gallate (EGCG) as the main active compound, is a topical formulation indicated for the treatment of genital warts. Polyphenon E has also shown to be very effective in the treatment of periungual and plane warts. Here, we report a dramatic clinical effect of topical treatment with polyphenon E in a subject with multiple "seborrheic keratosis-like" lesions of the genital area. Read More

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http://dx.doi.org/10.1159/000503989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902246PMC
November 2019