Curr Med Res Opin 2020 09 28;36(9):1433-1439. Epub 2020 Jul 28.
Center for Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, China.
Objective: The sex, age, medical history, treatment, tobacco use, race risk (SAMe-TTR) Score; the sex, age, medical history, treatment, tobacco use, genotype combination (SAMe-TTG) Score; and the so-called modified SAMe-TTR scores have been proposed to predict the anticoagulation quality for patients with non-valvular atrial fibrillation (NVAF). The data from a prospective controlled study is used to validate the SAMe-TTR and SAMe-TTG scores in Chinese NVAF patients treated with warfarin and to evaluate the association of factors with time in therapeutic range (TTR) to predict the quality of oral anticoagulation control.
Methods: A total of 379 patients with NVAF under warfarin treatment for a three-month follow-up were included in this prospective, multicenter study. Read More