Search Our Scientific Publications & Authors

J Pediatr Endocrinol Metab 2020 May 24. Epub 2020 May 24.

Department of Paediatric Endocrinology, Bristol Royal Hospital for Children, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.

Objectives Prader-Willi Syndrome (PWS) is characterised by hyperphagia often leading to obesity; a known risk factor for insulin resistance and type 2 (T2) diabetes. We present a prepubertal girl with PWS who developed diabetes. Case presentation Our case was diagnosed with PWS in infancy following investigation for profound central hypotonia and feeding difficulties. Read More

BMC Infect Dis 2020 Apr 19;20(1):287. Epub 2020 Apr 19.

Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen, 518036, China.

Background: Accurate identification Candida is important for successful therapy and epidemiology study. The aim of research is to study API 20C yeast identification system identification rate by using molecular identification as gold standard and tested the antifungal susceptibility of Candida from patients with vulvovaginal candidiasis (VVC).

Methods: In total, 3574 yeast isolates were obtained from patients with VVC. Read More

Benef Microbes 2020 May 4;11(3):303. Epub 2020 May 4.

John A Burns School of Medicine, University of Hawaii, 651 Ilalo Street, Honolulu HI, 96813, USA.

The recently published article by P. Tsimaris (2019) gave great prospective insight into non-traditional clinical applications of probiotic use as alternative and/or complementary therapeutics to traditional antibiotics for treatment of vulvovaginitis. However, these findings are too broad to be generalised as a treatment option for all women. Read More

Eur J Clin Microbiol Infect Dis 2020 Apr 30. Epub 2020 Apr 30.

Department of Bioscience Engineering, Research group Environmental Ecology and Microbiology, University of Antwerp, Antwerp, Belgium.

In vitro studies suggest that certain probiotic bacterial strains have potential activity against opportunistic infections such as Candida. There are few in vivo trials using probiotics as a single treatment for acute Candida vulvovaginitis (CV). In this open-label, proof-of-concept study, selected Lactobacillus strains were tested in women with acute Candida vaginitis. Read More

J Mycol Med 2020 Apr 5:100966. Epub 2020 Apr 5.

Department of Medical Mycology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran; Invasive Fungi Research Center, Mazandaran University of Medical Sciences, Sari, Iran.

Candida africana has been recovered principally as a causative agent of vulvovaginal candidiasis (VVC) from different countries, which is likely to be misidentified as the typical Candida albicans or Candida dubliniensis. The current study aimed to characterize C. albicans species complex obtained from VVC based on conventional and molecular assays. Read More

Clin Obstet Gynecol 2020 Apr 10. Epub 2020 Apr 10.

Department of Pediatrics, Division of Adolescent/Young Adult Health, Vanderbilt University Medical Center, Nashville, Tennessee.

Vulvovaginitis is a common gynecologic complaint in prepubertal girls. It typically presents with complaints of vulvovaginal itching, burning, irritation, discharge, or skin changes. Prepubertal females have anatomic, physiological, and behavioral factors that most often contribute to the development of symptoms. Read More

Pediatr Ann 2020 Apr;49(4):e170-e175

Vaginitis presents with vaginal discharge, odor, pruritis, and/or discomfort and affects up to 75% of girls and women over the course of their lifetimes, with most women experiencing their first episode during adolescence. Given the prevalence of this disorder, this article aims to provide an overview of vaginitis for the general pediatrician. We start with prepubertal etiologies of vaginitis, then discuss pubertal and normal physiologic discharge, and then focus on the most common etiologies of adolescent vulvovaginitis. Read More

Zhonghua Fu Chan Ke Za Zhi 2020 Mar;55(3):177-182

Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China.

To detect karyotype homology of vaginal isolates from patients with recurrent vulvovaginal candidiasis (RVVC) in recurrent episodes, and to discuss changes of susceptibility of Candida strains to antifungal drugs with clinical progress. s Ten patients were recruited from Beijing Obstetrics and Gynecology Hospital, Capital Medical University from September 2018 to June 2019, who were firstly diagnosed with RVVC. Vaginal discharges were collected before first treatment and after first relapse. Read More

Diagn Microbiol Infect Dis 2020 Jun 14;97(2):115024. Epub 2020 Feb 14.

Femicare Clinical Research for Women, Tienen, Belgium.

Background: It is commonly stated that Candida in the vagina prefers a low pH to develop infection. However, mixed infections of Candida with bacterial vaginosis (BV) and aerobic vaginitis (AV) are rather common and may challenge the rule that Candida should only be looked for in low vaginal pH settings. In this study we tested whether the vaginal pH in acute vaginal candidosis is lower than in women successfully treated to prevent Candida recurrences. Read More

Clinics (Sao Paulo) 2020 23;75:e1508. Epub 2020 Mar 23.

Departamento de Tocoginecologia, Faculdade de Ciencias Medicas, Universidade Estadual de Campinas, Campinas, SP, BR.

Objectives: Evidence suggests that infection or inflammation is a major contributor to early spontaneous preterm birth (sPTB). Therefore, this study aimed to investigate the development and causes of maternal infection associated with maternal and neonatal outcomes in women with sPTB.

Methods: This was a secondary analysis of a multicenter cross-sectional study with a nested case-control component, the Brazilian Multicentre Study on Preterm Birth (EMIP), conducted from April 2011 to July 2012 in 20 Brazilian referral obstetric hospitals. Read More

J Fungi (Basel) 2020 Mar 11;6(1). Epub 2020 Mar 11.

Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA 70112, USA.

Disease is a complex outcome that can occur as a result of pathogen-mediated damage, host-mediated damage or both. This has led to the revolutionary concept of the damage response framework (DRF) that defines microbial virulence as a function of host immunity. The DRF outlines six scenarios (classes) of host damage or beneficial outcomes, depending on the microbe and the strength of the immune response. Read More

Int J Womens Health 2020 30;12:49-57. Epub 2020 Jan 30.

Postgraduate Program in Health Sciences, Medical School, Federal University of Uberlândia, Uberlândia, Minas Gerais, Brazil.

Background: This study aims to investigate the occurrence of vulvovaginal infections, to describe and to relate the hygiene habits of women who were treated at the Units of Primary Attention to Family Health in a municipality in the interior of Brazil.

Methods: This was a cross-sectional study that was carried out in two Primary Health Care Units of the Family of Uberlândia, Minas Gerais, Brazil. The population sample consisted of 100 women who underwent gynecological consultation in the health units. Read More

Semergen 2020 Feb 20. Epub 2020 Feb 20.

Allergy Department, Hospital Universitario Ramón y Cajal, IRYCIS, ARADyAL, Madrid, Spain.

J Vasc Surg Cases Innov Tech 2020 Mar 1;6(1):1-5. Epub 2020 Feb 1.

West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Prepubertal vaginal discharge is most commonly caused by vulvovaginitis and is rarely caused by lymphatic malformations, resulting in chylous vaginal discharge. The diagnosis of chylous vaginal discharge remains a challenge because of a knowledge gap. We describe a 12-year-old girl with intermittent vaginal discharge for 10 years. Read More

J Med Life 2019 Oct-Dec;12(4):368-373

MedSwiss Medical Center, Moscow, Russian Federation.

Traditional therapy and extensive use of medications and intravaginal autolymphocyte therapy show different results of the treatment of vulvovaginal infections. The purpose of the article was to explore safe and highly effective methods to treat vulvovaginal infections and diseases of the pelvic organs. The standard clinical and laboratory screening of 70 patients of reproductive age was carried out to diagnose the diseases of the reproductive tract. Read More

BMC Complement Med Ther 2020 Jan 30;20(1):25. Epub 2020 Jan 30.

Botany and Microbiology Department, College of Science, King Saud University, P.O. 2455, Riyadh, 11451, Saudi Arabia.

Background: Candida vaginitis is a global health hazard that increases morbidity among women of childbearing age. Recent studies have revealed a high incidence of drug-resistant Candida strains. Additionally, treating Candida vulvovaginitis during pregnancy is challenging as antifungal therapy is associated with fetal abnormalities. Read More

Ann Clin Microbiol Antimicrob 2020 Jan 28;19(1). Epub 2020 Jan 28.

Department of Human Genetics, Guru Nanak Dev University, Amritsar, 143005, India.

Recurrent vulvovaginal infections (RVVI) has not only become an epidemiological and clinical problem but also include large social and psychological consequences. Understanding the mechanisms of both commensalism and pathogenesis are necessary for the development of efficient diagnosis and treatment strategies for these enigmatic vaginal infections. Through this review, an attempt has been made to analyze vaginal microbiota (VMB) from scratch and to provide an update on its current understanding in relation to health and common RVVI i. Read More

Support Care Cancer 2020 Jun 22;28(6):2507-2512. Epub 2020 Jan 22.

UOSD Ostetricia e Ginecologia - Procreazione Medicalmente Assistita, IRCCS Fondazione Policlinico "S. Matteo", Università degli Studi di Pavia, Pavia, Italy.

Purpose: VVA is a common disease, with approximately 50% of all postmenopausal women having related symptoms. VVA has a significant impact on the personal and sexual lives and on many aspects of women's self-esteem and emotional well-being. It is particularly frequent and severe in patients treated for BC, where it originates significant economic and social costs. Read More

Benef Microbes 2019 Dec;10(8):867-872

2nd Department of Obstetrics and Gynecology, Athens University, Medical School, Aretaieion Hospital, 76 Vassilissis Sofias Avenue, PC 11528, Athens, Greece.

Disruption of vaginal microbiota equilibrium promotes infectious clinical syndromes with annoying symptoms, such as vaginal discharge, odour, irritation, pruritus, and vulvar burning. Although identifying and eradicating the pathogen involved has been the standard of care, regional microbiota restoration with probiotics has been gaining ground in recent years. This study aimed to assess the effectiveness of topical treatment for patients exhibiting vaginal discomfort symptoms. Read More

BMC Infect Dis 2020 Jan 13;20(1):32. Epub 2020 Jan 13.

Department of Microbiology, Health Sciences Center, Kuwait University, Jabriya, Kuwait.

Background: Vaginal candidiasis is frequent in pregnant women and is associated with sepsis and adverse neonatal outcomes. This study determined the prevalence of candida species in symptomatic pregnant women and evaluated the antifungal susceptibility profile of the isolated Candida strains. It also aimed to explore whether Candida species predicts gestational complications and adverse neonatal outcomes. Read More

Eur J Med Res 2020 Jan 4;25(1). Epub 2020 Jan 4.

Microbiology Department, Regional Laboratory at King Saud Medical City, P.O. 2897, Riyadh, 11196, Saudi Arabia.

Background: Vulvovaginal candidiasis (VVC) represents a universal health hazard that contributes to significant morbidity in women. Resistance of Candida to antifungal therapy has been reported as a public health problem. So, the objective of our current study is to detect resistance profile of different candidal strains. Read More

Future Microbiol 2019 11 17;14:1349-1355. Epub 2019 Dec 17.

Fondazione Policlinico Universitario A Gemelli IRCCS, Dipartimento di Scienze di Laboratorio e Infettivologiche, Rome, Italy.

Mixed vaginitis is defined as the simultaneous presence of at least two different vaginal pathogens, both contributing to an abnormal vaginal milieu leading to signs and symptoms. Pathogen coinfection occurs frequently in women with vaginitis, and both coinfection and mixed vaginitis have relevant clinical and therapeutic implications. Fenticonazole, an imidazole derivative with a broad spectrum of antimycotic and antimicrobial activity, appears at least as effective as other topical antifungals in the treatment of vulvovaginal candidiasis and can also have a major role in the treatment of mixed infections or coinfections of the lower genital tract. Read More

J Sex Med 2020 Jan 4;17(1):117-125. Epub 2019 Dec 4.

School of Medicine, University of California San Francisco, San Francisco, CA.

Introduction: Clinical research and management of postmenopausal vaginal symptoms have been limited by the lack of validated measures for assessing symptom impact.

Aim: To evaluate convergent-divergent validity of the Day-to-Day Impact of Vaginal Aging (DIVA) questionnaire among postmenopausal women with moderate-to-severe vulvovaginal symptoms and identify demographic and clinical factors associated with greater symptom impact.

Methods: We examined baseline data from postmenopausal women with moderate-to-severe vulvovaginal itching, pain, irritation, dryness, or pain with intercourse in a randomized trial of vaginal estradiol, moisturizer, or placebo. Read More

J Pediatr Adolesc Gynecol 2020 Apr 22;33(2):120-124. Epub 2019 Nov 22.

Department of Gynecology, Fujian Provincial Maternity and Children's Hospital, Fuzhou, China. Electronic address:

Study Objective: This study characterizes the etiology, clinical features and outcomes of prepubescent vaginal bleeding and summarizes our experience.

Design: The data of patients who were hospitalized with vaginal discharge or bleeding treated from January 2012 to December 2018 were retrospectively reviewed.

Setting: A provincial Grade III Level A Maternity and Children's Hospital. Read More

PLoS One 2019 22;14(11):e0225036. Epub 2019 Nov 22.

Pediatrics Department, Botucatu Medical School, São Paulo State University (UNESP),Botucatu city, São Paulo State, Brazil.

Objective: To investigate the repercussion of periodontal disease (PD) in the pregnant woman health and the complications during pregnancy and delivery, as well as negative outcomes for the newborn (as infections, prematurity, low birth weight and fetal growth restriction).

Method: Retrospective cohort study, based on medical records of 142 pregnant women assisted at a prenatal service of usual risk between 2012-2014, with a dental evaluation for PD. Maternal variables, along with labor and newborn variables, were analyzed. Read More

Curr Infect Dis Rep 2019 Nov 9;21(11):44. Epub 2019 Nov 9.

Department of Internal Medicine, Wayne State University School of Medicine, 540 E. Canfield St., 1241 Scott Hall, Detroit, MI, 48021, USA.

Purpose Of Review: Goal was to review epidemiology, pathophysiology, and prevention of post-antibiotic Candida vulvovaginitis (VVC).

Recent Findings: Antibacterial therapy, whether systemic or locally applied to the vagina, represents the single most frequent and predictable cause or triggering mechanism of symptomatic vulvovaginal candidiasis (VVC). Such initiating mechanisms may precipitate sporadic or recurrent episodes of VVC. Read More

Lett Appl Microbiol 2020 Feb 5;70(2):95-101. Epub 2019 Dec 5.

The Department of Dermatovenereology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.

Candida albicans is an opportunistic fungus, which causes vulvovaginal candidiasis (VVC). The aim of this study was to evaluate Mrr2 mutation and its expression levels and Candida drug resistance 1 (Cdr1) in C. albicans associated with fluconazole (FCA) resistance. Read More

Gynecol Obstet Invest 2020 6;85(1):88-93. Epub 2019 Nov 6.

Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy.

Objectives: The aim of this work is to evaluate the susceptibility profile of the isolates against antifungal drugs and the level of virulent genes and resistant genes mRNA expression of Candida nivariensis.

Methods: We analyzed a collection of 9 C. nivariensis isolates from clinical isolates of Candida glabrata complex isolated from patients with vulvovaginal candidiasis (VVC). Read More

Appl Microbiol Biotechnol 2019 Nov 28;103(21-22):9037-9055. Epub 2019 Oct 28.

College of Life Science, Jiangsu Normal University, Xuzhou, 221116, Jiangsu Province, People's Republic of China.

The invasion of Candida albicans is one of the most common fungal infections seen in clinical practice, and serious drug resistance has been reported in recent years. Therefore, new anti-C. albicans drugs must be introduced. Read More

J Am Osteopath Assoc 2019 Nov;119(11):768-771

Pelvic malalignment is a somatic dysfunction that can lead to pelvic discomfort, despite normal genital examination findings. A 3-year-old girl presented with vulvar discomfort after a straddle injury sustained while riding a tricycle. The symptoms persisted despite standard medical treatment for vulvovaginitis and chronic vulvar irritation. Read More

BMC Infect Dis 2019 Oct 22;19(1):879. Epub 2019 Oct 22.

Department of Community Medicine, Faculty of Medicine, University of Science and Technology, Sana'a, Yemen.

Background: In Yemen, the underlying causes of infectious vaginitis have been neglected. Therefore, this study aimed to determine the prevalence and risk factors associated with bacterial vaginosis (BV), vulvovaginal candidiasis (VVC) and trichomonal vaginitis (TV) among non-pregnant reproductive-aged women.

Methods: A cross-sectional study was conducted among 347 non-pregnant reproductive-aged women seeking primary healthcare in Sana'a city, Yemen. Read More

Rev Colomb Obstet Ginecol 2019 03;70(1):49-56

Industrial Engineer, Master in Applied Statistics. Caribbean Infectious Diseases and Microbial Resistance Research Group, Universidad Metropolitana, Barranquilla (Colombia).

Objective: To determine the prevalence of potentially pathogenic microbiological agents in vaginal exudates in a sample of asymptomatic pregnant women in the Department of Atlantico, Colombia.

Methods: Descriptive cross-sectional study of a sample of asymptomatic pregnant women who attended a private primary healthcare institution in Barranquilla, Colombia, between 2014 and 2015. Pregnant women having received antimicrobial treatment within the last 30 days, with vaginal bleeding, mental disability or immunosuppression, were excluded. Read More

J Pak Med Assoc 2019 Aug;69(Suppl 3)(8):S50-S54

Department of Obstetrics & Gynecology, Al- Mustansiriya University, Baghdad, Iraq.

Objective: To investigate the effect of blood group ABO antigens on the risk of vaginosis.

Methods: The cross-sectional study was conducted at the Department of Obstetrics and Gynaecology, Al-Yarmouk Teaching Hospital, Baghdad, Iraq, from April 2016 to June 2017. Two vaginal swabs and 1ml of stimulated saliva from women aged16-46 years were collected. Read More

BMC Pregnancy Childbirth 2019 Sep 23;19(1):341. Epub 2019 Sep 23.

Kintampo Health Research Centre, P. O. Box 200, Kintampo, Bono East, Ghana.

Background: Vaginal infections usually caused by Candida sp, organisms responsible for bacterial vaginosis and Trichomonas vaginalis are associated with considerable discomfort and adverse outcomes during pregnancy and child birth. The study determined the prevalence of vulvovaginal candidiasis (VVC), bacterial vaginosis (BV) and trichomoniasis (TV) in pregnant women attending antenatal clinic at the Kintampo Municipal Hospital.

Methods: A study adopted a cross sectional design and recruited 589 pregnant women after seeking their informed consent from September, 2014 to March, 2015. Read More

Am J Obstet Gynecol 2020 02 9;222(2):114-122. Epub 2019 Sep 9.

Indiana University School of Medicine, Indianapolis, IN.

Vaginitis is one of the most common causes of patient visits to gynecologists, primary care providers, and urgent care centers. However, many women leave without a clear diagnosis or experience recurrent symptoms despite treatment. The 3 most common etiologies of vaginitis are trichomonas, bacterial vaginosis, and vulvovaginal candidiasis, which account for an estimated 70% of cases. Read More

J Womens Health (Larchmt) 2019 09;28(9):1179

Department Obstetrics, Gynecology and Reproductive Sciences, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey.

J Mycol Med 2019 Dec 27;29(4):317-319. Epub 2019 Aug 27.

Centre International de Recherches Médicales de Franceville, BP 769, Franceville, Gabon.

Background: Vulvovaginal candidiasis (VVC) is one of the most common lower genital tract infections in women; this unpleasant and extremely embarrassing pathology is one of the main reasons for gynaecological consultation. In Gabon, the prevalence of VVC remains poorly described even though VVC is known to be the leading gynaecological condition in several countries. This retrospective cross-sectional study sought to assess the prevalence of VVC among symptomatic women in southeastern Gabon. Read More

Infect Dis Obstet Gynecol 2019 28;2019:5016810. Epub 2019 Jul 28.

Faculty of Public Health, Lebanese German University (LGU), Sahel Alma, Lebanon.

Objective: species colonize the vagina in at least 20% of women, with rates rising to 30% during pregnancy. This study aimed at determining the prevalence and risk factors of vulvovaginal candidiasis (VVC) in pregnant women at 35-37 weeks of gestation. It also aims at finding possible correlations between VVC and vaginal colonization by other agents, such as Group B (GBS) and bacterial vaginosis. Read More

J Adv Vet Anim Res 2019 Mar 3;6(1):60-65. Epub 2019 Feb 3.

Fundamental and Applied Research for Animals & Health (FARAH), Sustainable Animal Production, Faculty of Veterinary Medicine, University of Liege, Liege, Belgium.

Objective: The present study was conducted to estimate the seroprevalence and associated risk factors of bovine herpesvirus 1 (BoHV-1) in a dairy herd in the northeast of Algiers, Algeria.

Materials And Methods: The target area is in the northeast of Algiers with humid to semi-dry climate and known for its economically important production of cattle. A total of 1,066 randomly selected individual blood samples of dairy herd collected at 120 dairy farms from rural districts of northeast of Algiers were evaluated with antibodies against BoHV-1 using commercial enzyme-linked immunosorbent assay kits, to determine the BoHV-1 infection status of the herds. Read More

J Pediatr Urol 2019 Dec 27;15(6):659.e1-659.e5. Epub 2019 Jul 27.

Child Health Literacy, Edge Hill University, Ormskirk, UK.

Introduction: Vulvovaginitis is described as a common self-limiting paediatric gynaecological condition. Parents' experiences of their child being diagnosed with this condition and subsequent treatment have not previously been described.

Aim: The aim of this study was to explore parents' experiences of their child's diagnosis and management of vulvovaginitis. Read More

BJOG 2019 12 18;126(13):1546-1552. Epub 2019 Sep 18.

Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, School of Medicine, the First Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang, China.

Background: Oral fluconazole is used to treat vulvovaginal candidiasis during pregnancy. However, there are concerns regarding the pregnancy outcomes following exposure to fluconazole.

Objectives: To evaluate the pregnancy outcomes associated with exposure to oral fluconazole during the first trimester of pregnancy. Read More

J Pediatr Adolesc Gynecol 2019 Dec 21;32(6):574-578. Epub 2019 Aug 21.

Laboratory Medicine, Lithuanian University of Health Sciences, Kaunas, Lithuania.

Study Objective: To evaluate genital microbiological findings in prepubertal girls with vulvovaginitis and in healthy controls.

Design: Prospective case-control study.

Setting: Pediatric Outpatient unit of the Department of Pediatrics of the Hospital of the Lithuanian University of Health Sciences Kauno Klinikos from November 2014 to May 2017. Read More

Contact Dermatitis 2020 Jan 28;82(1):57-59. Epub 2019 Aug 28.

Section of Dermatology, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.

Obstet Gynecol 2019 09;134(3):573-580

Department of Gynecology and Obstetrics, Emory University, School of Medicine, the Rwanda Zambia HIV Research Group, Department of Pathology & Laboratory Medicine, School of Medicine and Hubert Department of Global Health, Rollins School of Public Health, Emory University, and the Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia; the Department of Epidemiology, Ryals School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama; and the Department of Gynecology and Obstetrics, School of Medicine, University of Zambia, and the Ministry of Community Development, Mother and Child Health, Lusaka, Zambia.

Objective: To examine the relationship between hormonal contraception and vaginal infections with bacterial vaginosis, vaginal candidiasis, or trichomoniasis.

Methods: Couples who were human immunodeficiency virus (HIV) serodiscordant in Zambia were enrolled in a longitudinal cohort study. From 1994 to 2002, both partners were seen quarterly and received physical exams including genital examinations. Read More

J Midlife Health 2019 Apr-Jun;10(2):96-98

Department of Radiation Oncology, American Oncology Institute, Hyderabad, Telangana, India.

Amebiasis is a common protozoan disease with a worldwide distribution. It is endemic in tropical developing countries, and cases are being detected in subtropical countries as well. It usually presents with intestinal manifestations. Read More

Med Sante Trop 2019 May;29(2):195-199

Hôpital national Ignace-Deen, Conakry, Guinée.

Sexual violence is widespread in the world and has a negative impact on women's mental, social, and physical well-being. The purpose of this study was to describe the epidemiological and clinical aspects of the occurrence of sexual violence among patients seen in the Gynecology-Obstetrics department at Ignace Deen National Hospital. This is a cross-sectional, descriptive, observational study of victims of sexual violence seen in the department, directly or on court orders, during the two-year period from May 1, 2016, to April 30, 2018. Read More

Mycoses 2019 Nov 25;62(11):1043-1048. Epub 2019 Aug 25.

Department of Infectious Diseases, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

The aim of this study was to estimate the annual burden of fungal infections in Sweden using data mainly from 2016. Data on specific populations were obtained from Swedish national data registries. Annual incidence and prevalence of fungal disease was calculated based on epidemiological studies. Read More

Pathog Dis 2019 06;77(4)

School of Pharmacy, Health Science Center, Xi'an Jiaotong University, No. 76 YantaWestroad, Xi'an, People's Republic of China 710061.

External beam radiotherapy increases the risk of Candida vaginitis in cervical cancer patients, which brings a lot of insufferable influence to their life. Here, we explored the efficacy of alkannin in the treatment of Candida vaginitis after external beam radiotherapy. We exploit thermosensitive hydrogel-mediated alkannin as the topical formulation in a rat model established in our work. Read More

Future Microbiol 2019 07 2;14:839-846. Epub 2019 Aug 2.

School of Life Sciences, Jilin University, Changchun, 130012, Jilin Province, China.

The primary objective of this study was to evaluate the effects of polypeptide-enriched extracts (GE) on vulvovaginal candidiasis (VVC). A VVC model induced by () infection was successfully developed in BALB/c mice. After treatment, the colony-forming unit (CFU) of vaginal lavage was measured by plating. Read More

Eur Rev Med Pharmacol Sci 2019 Jul;23(14):6035-6044

Department of Surgical and Medical Sciences and Translational Medicine, Sant'Andrea University Hospital, Sapienza University of Rome, Rome, Italy.

Objective: This is a pilot study to evaluate the effectiveness of the treatment with Vaginal Soft gels technology in the improvement of common signs and symptoms in postmenopausal, postpartum and with recurrent vulvovaginitis patients. These conditions may cause the onset of Vulvovaginal Atrophy (VVA) with effects on sexual activity, self-confidence and daily activities. The main symptoms are itching, irritation and dryness. Read More