5,636 results match your criteria Vitreous Hemorrhage


Application of scanning electron microscopy in the auxiliary diagnosis of death caused by potassium chloride intravenous injection: a case report.

Int J Legal Med 2020 Jun 30. Epub 2020 Jun 30.

Department of Forensic Medicine, Faculty of Basic Medical Sciences, Chongqing Medical University, Chongqing, 400016, China.

To determine the cause of death, in addition to routine autopsy, some assisted techniques are imperative to achieve a definite diagnosis. Herein, we report a case of 36-year-old man who was found dead in his apartment. Medical drug containers (potassium chloride, zolpidem, and propofol) and medical instruments (syringes and indwelling needles) were also found at the scene. Read More

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http://dx.doi.org/10.1007/s00414-020-02361-6DOI Listing

Pars Plana Vitrectomy Reoperations for Complications of Proliferative Diabetic Retinopathy.

Clin Ophthalmol 2020 10;14:1559-1563. Epub 2020 Jun 10.

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.

Objective: To report visual acuity in patients undergoing pars plana vitrectomy (PPV) reoperations for complications of proliferative diabetic retinopathy (PDR).

Design: Retrospective case series.

Subjects: Diabetic patients undergoing reoperation with PPV between 2015 and 2018 at a university referral center. Read More

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http://dx.doi.org/10.2147/OPTH.S252285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293964PMC

Comparison of Characteristics and Clinical Outcomes in 27-Gauge versus 23-Gauge Vitrectomy Surgery.

Clin Ophthalmol 2020 9;14:1553-1558. Epub 2020 Jun 9.

Department of Special Surgery/Ophthalmology Division, School of Medicine, The University of Jordan, Amman, Jordan.

Purpose: To compare characteristics, clinical outcomes and complication profiles of a cohort of patients undergoing 27-gauge versus 23-gauge vitrectomy surgery at a tertiary medical center in the Middle East.

Methods: This is a retrospective comparative study of indication-matched patients undergoing 27-gauge versus 23-gauge pars plana vitrectomy for a set of predetermined diagnoses. Data including indications for surgery, clinical exams, visual outcomes, and complications were documented and analyzed. Read More

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http://dx.doi.org/10.2147/OPTH.S255162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293406PMC

Vitreous and Serum Concentrations of Vascular Endothelial Growth Factor and Platelet-Derived Growth Factor in Proliferative Diabetic Retinopathy.

Clin Ophthalmol 2020 9;14:1547-1552. Epub 2020 Jun 9.

Department of Ophthalmology, Faculty of Medicine, Hasanuddin University, Makassar, South Sulawesi, Indonesia.

Purpose: This study aimed to investigate the concentrations of vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) in vitreous and serum samples, analyze the ratio, and compare among proliferative diabetic retinopathy (PDR) subgroups.

Patients And Methods: This study included 17 eyes of patients with PDR, identified as the PDR group which was divided into three subgroups (vitreous hemorrhage [VH], VH with fibrotic tissues, and tractional retinal detachment), and five control eyes (nucleus and intraocular lens drop). Vitreous and serum samples were obtained on the same day. Read More

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http://dx.doi.org/10.2147/OPTH.S248812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293416PMC

8-0 Polypropylene Suture Looping and Overhand Knot: Transconjunctival Approach to Four-Point Scleral Fixation of an Akreos Adapt Intraocular Lens.

Retina 2020 Jun 26. Epub 2020 Jun 26.

Eye Hospital of Shandong First Medical University, State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China.

Purpose: To evaluate a novel surgical technique for transscleral fixation of the intraocular lens (IOL) with four hollow haptics using 8-0 polypropylene suture looping and overhand knot.

Methods: An 8-0 polypropylene suture was tied to a 10-0 polypropylene suture with an overhand knot. One set of 8-0 polypropylene suture was then passed through the IOL four haptics. Read More

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http://dx.doi.org/10.1097/IAE.0000000000002873DOI Listing

Ultra wide field angiography documented peripheral retinal eovascularization as cause of vitreous hemorrhage after scleral buckle surgery.

J Surg Case Rep 2020 Jun 19;2020(6):rjaa142. Epub 2020 Jun 19.

Department of Ophthalmology, Loma Linda University School of Medicine, Loma Linda, CA, USA.

We describe an unusual case of ultra wide fluorescein angiography (UWFA) documented peripheral retinal neovascularization (NVE) with delayed vitreous hemorrhage after placement of an encircling scleral buckle (a common procedure for repair of retinal detachment). Anterior segment ischemia is a rare complication after scleral buckle surgery for the treatment of retinal detachment and results from altered choroidal flow through the impingement of the anterior and long posterior ciliary arteries. UWFA performed for the evaluation of vitreous hemorrhage confirmed ischemia anterior to the scleral buckle and consequential NVE. Read More

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http://dx.doi.org/10.1093/jscr/rjaa142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303102PMC

Congenital Hypofibrinogenemia; An Unexpected Culprit Of Blindness In An Infant.

J Ayub Med Coll Abbottabad 2020 Apr- Jun;32(2):268-270

Department of Medicine, Khyber Teaching Hospital, Peshawar, Pakistan.

Congenital hypofibrinogenemia is a rare haematological disorder in which the production of functional fibrinogen is impaired because of the inherited mutation. Hypofibrinogenemia affects the coagulation cascade leading to bleeding diathesis and one of its manifestations can be recurrent Vitreous haemorrhages, sometimes leading to irreversible loss of vision. Therefore, Hypofibrinogenemia must be included in the differential diagnosis of Vitreous haemorrhage, particularly in young children. Read More

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Anti-Vascular Endothelial Growth Factor Therapy as an Alternative or Adjunct to Pan-Retinal Photocoagulation in Treating Proliferative Diabetic Retinopathy: Meta-Analysis of Randomized Trials.

Front Pharmacol 2020 5;11:849. Epub 2020 Jun 5.

Department of Ophthalmology, Ruijin Hospital Affiliated Shanghai Jiaotong University School of Medicine, Shanghai, China.

Aim: To compare anti-vascular growth factor (anti-VEGF) pharmacotherapy with pan-retinal photocoagulation (PRP) for proliferative diabetic retinopathy (PDR).

Method: PubMed, Embase, Medline, the ClinicalTrials.gov and the Cochrane Central Register of Controlled Trials were reviewed systemically. Read More

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http://dx.doi.org/10.3389/fphar.2020.00849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289996PMC

Management and Visual Outcomes of Acute Bacterial Endophthalmitis Following Intravitreal Injection of Contaminated Bevacizumab in a Single Day.

Ophthalmic Surg Lasers Imaging Retina 2020 Jun;51(6):346-352

Background And Objective: Bevacizumab requires compounding for off-label intravitreal injection, thus creating a risk of possible contamination during preparation.

Patients And Methods: This retrospective, consecutive case series from a single site included patients who developed culture-proven acute endophthalmitis after intravitreal injection with contaminated bevacizumab. All patients suspected of endophthalmitis had vitreous biopsy and microbial cultures prior to initiation of treatment and were managed with immediate tap and injection of antibiotics followed early by pars plana vitrectomy. Read More

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http://dx.doi.org/10.3928/23258160-20200603-05DOI Listing

[A Case of Radiation Necrosis in the Right Occipital Lobe Accompanied with Massive Hemorrhage:Histopathological Analysis].

No Shinkei Geka 2020 Jun;48(6):541-546

Department of Neurosurgery, Japanese Red Cross Fukuoka Hospital.

Radiation necrosis with massive hemorrhage is a rare complication of radiotherapy. We report the case of a male patient who had undergone radiotherapy therapy 18 years earlier and presently underwent gamma knife radiosurgery for a metastatic brain tumor in his right occipital lobe. The patient showed aberrant behavior with left homonymous hemianopsia and a gradual deterioration of cognitive function after radiotherapy. Read More

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http://dx.doi.org/10.11477/mf.1436204225DOI Listing

Surgical Treatment of Vitreoretinal Complications During Disseminated Intravascular Coagulation Secondary to Meningococcemia.

Retin Cases Brief Rep 2020 Jun 15. Epub 2020 Jun 15.

Department of Ophthalmology, Percy Military Hospital, 101 Avenue H. Barbusse, 92141 Clamart, France. Tel: +331.41.46.62.74. Fax : +331.41.46.64.91.

Purpose: To report a case of the surgical management of vitreoretinal complications during disseminated intravascular coagulation (DIC) secondary to meningococcemia.

Methods: Case report.

Results: A 25-year-old man presented with loss of vision due to retinal and vitreous hemorrhages during DIC secondary to meningococcemia. Read More

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http://dx.doi.org/10.1097/ICB.0000000000001017DOI Listing

Surgical management of uveitis-glaucoma-hyphema syndrome.

Int J Ophthalmol 2020 18;13(6):935-940. Epub 2020 Jun 18.

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

Aim: To report outcomes of patients after intraocular lens (IOL) repositioning or exchange for the version of the uveitis-glaucoma-hyphema (UGH) syndrome that does not include closed loop anterior chamber IOL (nUGH).

Methods: Chart review of patients with nUGH who underwent IOL repositioning or exchange by one surgeon were reviewed. The main outcome measures were best corrected visual acuity (BCVA) as a decimal fraction preoperatively and postoperatively after IOL repositioning or exchange. Read More

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http://dx.doi.org/10.18240/ijo.2020.06.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270258PMC

The BElfast Retinal Tear and detachment Score (BERT Score).

Eye (Lond) 2020 Jun 18. Epub 2020 Jun 18.

Royal Victoria Hospital, Belfast, UK.

Purpose: To establish a scoring system to triage patients presenting with symptoms of flashes and floaters to allow safe differentiation between those with retinal tears and detachments, versus uncomplicated posterior vitreous detachments (PVDs).

Methods: Prospective and retrospective audits of 153 patients presenting to eye casualty and vitreoretinal clinics to ascertain the clinical features most likely to be associated with retinal pathology, rather than simple PVD. We then developed a scoring system, which was applied to 160 patients in a further prospective audit. Read More

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http://dx.doi.org/10.1038/s41433-020-1025-7DOI Listing

Unusual Missed Diagnosis of Foreign Body: A Case Report.

Int Med Case Rep J 2020 19;13:187-190. Epub 2020 May 19.

Specialty Retina Centre, Coral Springs, FL, USA.

Background: Penetrating intraorbital foreign body (IOFB) is usually associated with high-velocity trauma forces around the eye. IOFB injury to globe or optic nerve is considered a surgical emergency; an immediate diagnosis and management plan is generally indicated.

Methods: A case report (design). Read More

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http://dx.doi.org/10.2147/IMCRJ.S246924DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245452PMC

Spontaneous Necrosis of a Large Choroidal Melanoma: Unusual Presentation in a 49-Year-Old Male.

Ocul Oncol Pathol 2020 May 5;6(3):174-179. Epub 2019 Dec 5.

St Paul's Eye Unit, Vitreoretinal Department and Liverpool Ocular Oncology Centre, Royal Liverpool University Eye Hospital, Liverpool, United Kingdom.

Purpose: To demonstrate a case of massive vitreous haemorrhage obscuring the underlying diagnosis of a large mixed-cell choroidal melanoma which had undergone spontaneous necrosis.

Case Report: A 49-year-old man in good general health suddenly lost vision in his right eye due to an extensive vitreous haemorrhage 1 day after a workout at the gym. He reported good vision prior to that without any symptoms of flashes, floaters, or shadows. Read More

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http://dx.doi.org/10.1159/000501522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250329PMC

Atypical ophthalmic manifestations of disseminated intravascular coagulation in a newborn.

J AAPOS 2020 Jun 3. Epub 2020 Jun 3.

Case Western Reserve University School of Medicine, Cleveland, Ohio; University Hospitals Eye Institute, Rainbow Babies and Children's Hospital, Cleveland, Ohio. Electronic address:

Ophthalmic manifestations of disseminated intravascular coagulation (DIC) in a newborn are rare. Ocular involvement typically involves the posterior segment bilaterally and manifests as choroidal and/or retinal hemorrhages associated with fibrin thrombi in the choriocapillaris. We present the case of a newborn girl with DIC secondary to sepsis who subsequently developed nonclearing hyphema, related secondary cataract, 360° posterior synechiae, and nonclearing vitreous hemorrhage in the right eye and diffuse retinal hemorrhage in the left eye. Read More

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http://dx.doi.org/10.1016/j.jaapos.2020.02.007DOI Listing

[Preventive laser treatment of tractional symptomatic retinal flap tears: long-term outcomes].

Vestn Oftalmol 2020 ;136(3):32-38

Tradomed Invest comp., Moscow, Russia.

Tractional flap tears are the main cause of the development of regmatogenic retinal detachment (RRD). The main immediate treatment method for it is laser retinal coagulation.

Purpose: Case monitoring of tractional symptomatic flap tears after laser treatment. Read More

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http://dx.doi.org/10.17116/oftalma202013603132DOI Listing
January 2020

Clinical and pathological characterization of persistent fetal vasculature associated with vitreous hemorrhage.

Am J Ophthalmol Case Rep 2020 Sep 18;19:100743. Epub 2020 May 18.

King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

Purpose: To provide clinical and pathological features of posterior persistent fetal vasculature (PFV) presenting with vitreous hemorrhage.

Observations: Case 1 was a one-year old male with PFV reaching up to the posterior lens capsule. Case 2 and 3 both had history of blunt trauma. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256462PMC
September 2020

Vitrectomy using the Eckardt temporary keratoprosthesis.

Am J Ophthalmol Case Rep 2020 Sep 1;19:100709. Epub 2020 May 1.

Bascom Palmer Eye Institute, Miami, FL, USA.

Purpose: to present the now vitrectomy technique through a limbus via preexisting holes in the Eckardt TKP.

Methods: the surgical technique performed in a case of four-year-old girl presented with a complete hyphema and vitreous hemorrhage in the left eye.

Results: the vitrectomy was performed vial a limbal approach from the TKP without making additional sclerotomies. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251374PMC
September 2020

Intravitreal ranibizumab alone or in combination with panretinal photocoagulation for the treatment of proliferative diabetic retinopathy with coexistent macular edema: long-term outcomes of a prospective study.

Acta Diabetol 2020 May 29. Epub 2020 May 29.

2nd Department of Ophthalmology, National and Kapodistrian University of Athens, Athens, Greece.

Aims: To compare intravitreal ranibizumab as monotherapy or in combination with panretinal photocoagulation (PRP) in patients with proliferative diabetic retinopathy (PDR) and coexistent diabetic macular edema (DME) in a long-term follow-up of 24 months.

Methods: Participants in this prospective study were 47 patients with PDR and concurrent DME, who were randomized at baseline into two groups: (i) the "ranibizumab alone" group (n = 23), which was treated with at least 3 intravitreal ranibizumab injections as a loading phase, and (ii) the "combination" group (n = 24), which was treated with PRP and at least 3 intravitreal ranibizumab injections. Thereafter, all patients were followed up at a pro re nata (PRN) basis, with regular monthly monitoring for 24 months. Read More

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http://dx.doi.org/10.1007/s00592-020-01548-yDOI Listing

Tubulointerstitial Nephritis and Uveitis Syndrome: Characterization of Clinical Features.

Ocul Immunol Inflamm 2020 May 28:1-6. Epub 2020 May 28.

Department of Ophthalmology, Northwestern University Feinberg School of Medicine , Chicago, Illinois, USA.

Purpose: To describe clinical manifestations of patients with tubulointerstitial nephritis and uveitis syndrome (TINU) with a focus on posterior segment findings.

Methods: Retrospective chart review.

Results: 17 patients were diagnosed with TINU. Read More

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http://dx.doi.org/10.1080/09273948.2020.1736311DOI Listing

B-HEX pupil expander in vitreoretinal surgery - A case series.

Indian J Ophthalmol 2020 Jun;68(6):1188-1191

Disha Eye Hospitals, Kolkata, West Bengal, India.

We describe the successful use of the B-HEX pupil expansion device in four cases of combined phacovitrectomy with significant cataract, non-dilating pupil, and surgical vitreoretinal pathologies including vitreous hemorrhage, inferior retinal detachment (RD) with proliferative vitreoretinopathy in an oil filled eye, recurrent rhegmatogenous RD, and macular hole with RD localized to the posterior pole in an eye with uveitic sequelae. The B-HEX remained well engaged and maintained excellent mydriasis throughout the surgery despite wide fluctuations in intraocular pressure and anterior chamber fluidics. This is the first series describing use of B-HEX for combined phacovitrectomy due to myriad causes. Read More

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http://dx.doi.org/10.4103/ijo.IJO_1675_19DOI Listing

Posterior segment complications following glaucoma surgeries.

Indian J Ophthalmol 2020 Jun;68(6):988-993

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS, New Delhi, India.

The present review describes the posterior segment complications following surgical management of glaucoma. Although the majority of glaucoma cases are managed medically, still a large number of patients may require surgery. Moreover, with the advent of newer surgical techniques and adjuncts, encountering retinal complications post-surgery is not uncommon. Read More

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http://dx.doi.org/10.4103/ijo.IJO_1040_19DOI Listing

Effectiveness of different silicone oil remove methods after vitrectomy and light silicone oil tamponade in elderly patients.

Ann Palliat Med 2020 May 8;9(3):1013-1019. Epub 2020 May 8.

Department of Ophthalmology, Liuzhou Hospital of Traditional Chinese Medicine, Liuzhou 545006, China.

Background: During the remove of oil from the silicone oil-filled eye after vitrectomy, perfusion fluid is often mistakenly aspirated when mechanical force is used to remove the oil. This leads to a sudden sharp drop in intraocular pressure and collapse of the eyeball, which may cause complications. The aspiration of perfusion fluid can be detected when the oil is removed manually, and the force of the hand and location of the aspiration can be adjusted to remove the silicone oil instead. Read More

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http://dx.doi.org/10.21037/apm-20-949DOI Listing

Adenoma and Adenocarcinoma of the Retinal Pigment Epithelium: A Review of 51 Consecutive Patients.

Ophthalmol Retina 2020 Mar 18. Epub 2020 Mar 18.

Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania. Electronic address:

Purpose: To describe the clinical and imaging characteristics, pathologic features, and management options of retinal pigment epithelium (RPE) adenoma/adenocarcinoma.

Design: Retrospective case series.

Participants: Fifty-one patients with RPE adenoma/adenocarcinoma. Read More

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http://dx.doi.org/10.1016/j.oret.2020.03.008DOI Listing

Relationships among Retinal Nonperfusion, Neovascularization, and Vascular Endothelial Growth Factor Levels in Quiescent Proliferative Diabetic Retinopathy.

J Clin Med 2020 May 13;9(5). Epub 2020 May 13.

Department of Ophthalmology, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea. #327 Sosa-ro, Wonmi-gu, Bucheon, Gyeonggi-do 14647, Korea.

Purpose: To investigate the relationships among the retinal nonperfusion (NP) area, neovascularization (NV) area, and aqueous humor vascular endothelial growth factor (VEGF) levels in quiescent proliferative diabetic retinopathy (PDR).

Methods: Forty-seven eyes from 47 patients with treatment-naïve PDR that did not show macular edema or vitreous hemorrhage were enrolled. NP area, NV number, and NV area were quantitatively measured using ultra-widefield fluorescein angiography in an automated manner. Read More

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http://dx.doi.org/10.3390/jcm9051462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290947PMC

Non-contact wide-angled visualization with chandelier-assisted scleral buckling for primary uncomplicated rhegmatogenous retinal detachment.

Graefes Arch Clin Exp Ophthalmol 2020 May 14. Epub 2020 May 14.

Asociados de Macula, Vitreo y Retina de Costa Rica, Primer Piso Torre Mercedes Paseo Colon, San Jose, Costa Rica.

Purpose: To report our experience in non-contact wide-angled visualization with chandelier-assisted scleral buckling (SB) in uncomplicated primary rhegmatogenous retinal detachments (RRD).

Methods: Retrospective case series of 282 eyes that underwent non-contact wide-angled visualization with chandelier-assisted SB and were followed for a mean of 13.5 months. Read More

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http://dx.doi.org/10.1007/s00417-020-04737-1DOI Listing

Modeling retinal detachment associated with hemorrhage by Monte Carlo simulation.

Authors:
Tarek A Al-Saeed

Appl Opt 2020 Apr;59(12):3614-3618

In this work we study fundus reflection in the case of retinal detachment. Vitreous humor builds up beneath the retina through a break in the retina or when there is traction on the retina. Further, we assume that this detachment is associated with hemorrhage in regions both above and below the retina. Read More

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http://dx.doi.org/10.1364/AO.385247DOI Listing

A Case of Choroidal and Vitreous Hemorrhage Following Micropulse Transscleral Cyclophotocoagulation.

J Glaucoma 2020 May 8. Epub 2020 May 8.

Department of Ophthalmology, University of North Carolina-Chapel Hill, Chapel Hill.

Choroidal hemorrhages involve bleeding into the potential space between the choroid and sclera and are a serious ocular complication. Common causes of choroidal hemorrhages include intraocular surgeries, such as scleral buckling, cataract extractions, and glaucoma filtering procedures, or trauma. We report a case of choroidal and vitreous hemorrhage after micropulse cyclophotocoagulation. Read More

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http://dx.doi.org/10.1097/IJG.0000000000001529DOI Listing

[Vitreous body hemorrhage-How long can one wait?]

Ophthalmologe 2020 May 8. Epub 2020 May 8.

Campus Kiel, Klinik für Augenheilkunde, Universitätsklinikum Schleswig-Holstein, Kiel, Deutschland.

In the case of acute vitreous body hemorrhage, the ophthalmologist is faced with the question of whether spontaneous absorption can be awaited or whether a vitrectomy is necessary. In addition to the intensity of the bleeding, the underlying cause also plays an important role. A thorough medical history is therefore important. Read More

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http://dx.doi.org/10.1007/s00347-020-01112-7DOI Listing

Early-onset type 2 diabetes: A high-risk factor for proliferative diabetic retinopathy (PDR) in patients with microalbuminuria.

Medicine (Baltimore) 2020 May;99(19):e20189

Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing.

We aim to explore the relationship between early-onset diabetes and proliferative diabetic retinopathy (PDR) in type 2 diabetes mellitus (T2DM) patients with microalbuminuria.A total of 461 T2DM patients with microalbuminuria were enrolled. Subjects were defined as early-onset or late-onset based on the age at which they were diagnosed with diabetes (<40 and ≥40 years, respectively). Read More

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http://dx.doi.org/10.1097/MD.0000000000020189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220424PMC

Efficacy and safety of Chinese medicines for vitreous hemorrhage: A protocol for systematic review and meta-analysis.

Medicine (Baltimore) 2020 May;99(19):e20086

Department of Ophthalmology, China-Japan Friendship Hospital, Beijing, China.

Background: Vitreous hemorrhage (VH) is a common ophthalmic disease with a high rate of blindness, which will seriously affect the quality of life of patients and bring great burden to patients' families and society. The treatment for VH contains medical therapy, lasers, and surgery. At present, there is no recognized western medicine with definite curative effect and little side effect for the treatment of VH. Read More

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http://dx.doi.org/10.1097/MD.0000000000020086DOI Listing

Henle fibre layer haemorrhage: clinical features and pathogenesis.

Br J Ophthalmol 2020 May 6. Epub 2020 May 6.

Retina Department, Vitreous Retina Macula Consultants of New York, New York, New York, USA.

Background: To describe the clinical presentation and characteristic imaging features of deep retinal haemorrhages primarily located in the Henle fibre layer (HFL) of the macula. The spectrum of aetiologies and a comprehensive theory of pathogenesis are presented.

Methods: This is a retrospective, multicentre case series evaluating eyes with retinal haemorrhage in HFL. Read More

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http://dx.doi.org/10.1136/bjophthalmol-2019-315443DOI Listing

Characteristics and treatments of ocular blast injury in Tianjin explosion in China.

BMC Ophthalmol 2020 May 6;20(1):185. Epub 2020 May 6.

Department of Ophthalmology, Tianjin Medical University General Hospital, No. 154, Anshan Road, Tianjin, 300052, China.

Background: To document characteristics and treatments of ocular blast injury from a fire and explosion.

Method: Authors retrospectively evaluated 116 patients with 166 eye injuries from six hospitals. Terminology of ocular injury referred to Birmingham Eye Trauma Terminology, and best-corrected visual acuity (BCVA) was categorized with the ocular trauma score (OTS) grading system. Read More

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http://dx.doi.org/10.1186/s12886-020-01448-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203803PMC
May 2020
1.075 Impact Factor

Plaque radiation for ciliary body medulloepithelioma presenting with neovascular glaucoma and vitreous hemorrhage in 13-year-old Asian girl.

Am J Ophthalmol Case Rep 2020 Jun 23;18:100719. Epub 2020 Apr 23.

L&T Ophthalmic Pathology Department, Sankara Nethralaya, 18 College Road, Chennai, 600006, Tamilnadu, India.

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http://dx.doi.org/10.1016/j.ajoc.2020.100719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191537PMC

Anterior Chamber Migration of Ozurdex Implants.

Turk J Ophthalmol 2020 Apr;50(2):115-122

Celal Bayar University Faculty of Medicine, Department of Ophthalmology, Manisa, Turkey.

We present patient characteristics and follow-up results of cases with anterior chamber dexamethasone implant migration. The common feature of all six presented cases was vitrectomized eyes. Four of the patients had sutured intraocular lens (IOL) implantation due to complicated cataract surgery, one had combined retinal detachment surgery with sutured IOL implantation, and one had vitrectomy for diabetic intravitreal hemorrhage cleaning and uncomplicated cataract surgery. Read More

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http://dx.doi.org/10.4274/tjo.galenos.2019.43778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204895PMC

Slit-shaped artificial pupil and very dense nuclear cataract after early iridoplasty: May consultation #1.

Authors:
Rupert Menapace

J Cataract Refract Surg 2020 May;46(5):797

A now-17-year-old girl was reportedly born with no pupil formed in her right eye. In her first week of life, she underwent attempted pupilloplasty at a foreign institution. Surgery was reported to have been complicated and followed by vitreous hemorrhage. Read More

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http://dx.doi.org/10.1097/j.jcrs.0000000000000199DOI Listing

Trans-scleral plugs fixated IOL: a new paradigm for sutureless scleral fixation.

J Cataract Refract Surg 2020 May;46(5):716-720

From the Department of Translational Surgery and Medicine, Ophthalmology, University of Florence, Careggi, Florence, Italy.

Purpose: To assess the surgical and refractive outcomes of a new technique of sutureless scleral fixation (SSF) using a single-piece foldable acrylic intraocular lens (IOL) (Carlevale).

Setting: Department of Translational Surgery and Medicine, Ophthalmology, University of Florence, Careggi, Florence, Italy.

Design: Prospective observational case series. Read More

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http://dx.doi.org/10.1097/j.jcrs.0000000000000135DOI Listing

Outcomes of Ahmed glaucoma valve in paediatric glaucoma following congenital cataract surgery in persistent foetal vasculature.

Eur J Ophthalmol 2020 Apr 30:1120672120919066. Epub 2020 Apr 30.

Hospital Universitario La Paz, Madrid, Spain.

Purpose: To evaluate the outcomes of primary Ahmed glaucoma valve in refractory secondary glaucoma following congenital cataract surgery, particularly in persistent foetal vasculature.

Method: Retrospective review of paediatric patients after Ahmed glaucoma valve implantation for refractory post-lensectomy glaucoma in a tertiary referral centre in Spain. Surgical complications, additional and/or replacements of Ahmed glaucoma valve, intraocular pressure, cup-to-disc ratio, glaucoma medications and final visual acuity were studied. Read More

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http://dx.doi.org/10.1177/1120672120919066DOI Listing

Quantification of Retinal Nonperfusion and Neovascularization With Ultrawidefield Fluorescein Angiography in Patients With Diabetes and Associated Characteristics of Advanced Disease.

JAMA Ophthalmol 2020 Apr 30. Epub 2020 Apr 30.

W. K. Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor.

Importance: Quantification of nonperfusion (NP) and neovascularization (NV) in diabetic retinopathy (DR) may identify better biomarkers of disease progression.

Objective: To identify demographic risk factors and markers of advanced DR that are associated with increased areas of NP and NV in eyes with disease ranging from no DR but diagnosed as having diabetes to proliferative DR (PDR) and to calculate a threshold total area of NP that may be associated with an increased risk of PDR.

Design, Setting, And Participants: This retrospective case series was performed on ultrawidefield fluorescein angiography (UWF FA) images from January 2009 to May 2018 at the University of Michigan Kellogg Eye Center. Read More

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http://dx.doi.org/10.1001/jamaophthalmol.2020.1257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193527PMC

ANATOMICAL AND VISUAL OUTCOMES IN STAGE 5 RETINOPATHY OF PREMATURITY WITH MICROINCISION VITRECTOMY SURGERY.

Retina 2020 Apr 28. Epub 2020 Apr 28.

Department of VitreoRetina, Shri Bhagwan Mahavir Vitreoretinal Services, Medical Research Foundation, Sankara Nethralaya, Chennai, India.

Purpose: To report anatomical and visual outcomes and potential prognostic factors with microincision vitrectomy surgery in Stage 5 retinopathy of prematurity.

Methods: The medical records of premature babies who underwent microincision vitrectomy surgery for Stage 5 retinopathy of prematurity using 23G, 25G, or 27G instrumentation and had a minimum follow-up of 6 weeks were, retrospectively, analyzed. Primary outcome measures were anatomical success at last follow-up defined as retinal attachment at the posterior pole and visual outcomes. Read More

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http://dx.doi.org/10.1097/IAE.0000000000002837DOI Listing

"Sutureless scleral fixation using Carlevale lens: surgical and refractive outcomes".

J Cataract Refract Surg 2020 Jan 21. Epub 2020 Jan 21.

Department of Translational Surgery and Medicine, Ophthalmology, University of Florence, Careggi, Florence, Italy.

Purpose: To assess the surgical and refractive outcomes of a new technique of sutureless scleral fixation (SSF) using a single-piece foldable acrylic Carlevale lens (Soleko) SETTING: Department of Translational Surgery and Medicine, Ophthalmology, University of Florence, Careggi, Florence, Italy DESIGN: Prospective observational case series METHODS: Thirty-two eyes of 32 patients with aphakia, dislocated IOL or subluxated lens who underwent sutureless scleral fixation (SSF) of a mono-piece hydrophobic acrylic Carlevale lens were studied. The patients' data including pre-operative and post-operative refractive status, complications during and after surgery were recorded. The intraocular lens tilt was evaluated using anterior segment (AS)- OCT. Read More

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http://dx.doi.org/10.1097/j.jcrs.0000000000000135DOI Listing
January 2020

Intraoperative Three-Dimensional Fluorescein Angiography-Guided Pars Plana Vitrectomy for the Treatment of Proliferative Diabetic Retinopathy: The Maximized Utility of the Digital Assisted Vitrectomy.

Retina 2020 Apr 17. Epub 2020 Apr 17.

Department of Surgery, Division of Ophthalmology, Kobe University Graduate School of Medicine, Kobe, Japan.

Purpose: To show the usefulness of the intraoperative three-dimensional fluorescein angiography (3D-FA)-guided pars plana vitrectomy.

Methods: The NGENUITY 3D visualization system was used for the digital assisted vitrectomy. Three-dimensional fluorescein angiography-guided pars plana vitrectomy was performed in three patients with vitreous hemorrhage secondary to proliferative diabetic retinopathy. Read More

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http://dx.doi.org/10.1097/IAE.0000000000002805DOI Listing

Combined aspirin and clopidogrel therapy in phacoemulsification cataract surgery: a risk factor for ocular hemorrhage?

Int Ophthalmol 2020 Apr 27. Epub 2020 Apr 27.

Department of Ophthalmology, Huashan Hospital, Fudan University, No. 12 Middle Urumqi Road, Shanghai, 200040, China.

Purpose: To evaluate the safety of phacoemulsification cataract surgery in the patients undergoing dual antiplatelet therapy with aspirin and clopidogrel.

Methods: Consecutive patients undergoing phacoemulsification cataract surgery with a clear corneal incision under topical anesthesia were eligible for inclusion in the study. Thirty-eight eyes from 38 patients on combined aspirin and clopidogrel therapy who continued the treatment were classified into the maintenance group, a matched group of 38 eyes from 38 patients on no antiplatelet/anticoagulant therapy as the control group. Read More

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http://dx.doi.org/10.1007/s10792-020-01378-5DOI Listing

Self-sealing posterior scleral perforation in airgun ocular trauma, surgical tip: a case report.

BMC Ophthalmol 2020 Apr 22;20(1):164. Epub 2020 Apr 22.

Department of Organ of Sense, Sapienza University of Rome, Viale del Policlinico, 155 00161, Rome, Italy.

Background: Intraorbital metallic foreign bodies have varied clinical presentations. Here, we report the unusual case of intraoperative evidence of spontaneously healed posterior scleral perforation in a severe ballistic trauma without previous instrumental signs of penetrating wound and complete visual restoration after surgery.

Case Presentation: The patient was hit by several lead hunting pellets in the chest, abdomen, limbs, face and orbit. Read More

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http://dx.doi.org/10.1186/s12886-020-01435-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178978PMC

Hemorrhagic complications associated with suprachoroidal buckling.

Int J Retina Vitreous 2020 16;6:10. Epub 2020 Apr 16.

1Department of Ophthalmology, Hôpital Maisonneuve-Rosemont, Université de Montréal, 5415 Assumption Blvd, Montréal, QC H1T 2M4 Canada.

Background: Multiple surgical techniques exist for the repair of rhegmatogenous retinal detachments (RRD). Suprachoroidal buckling (SCB), consisting of injecting viscoelastic material in the suprachoroidal space to allow chorioretinal apposition, has been recently described in the repair of RRD. The aim of this study is to report the complications of SCB and to propose measures to decrease their incidence during the learning curve. Read More

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http://dx.doi.org/10.1186/s40942-020-00211-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160972PMC

Primary Retinal Detachment Outcomes Study Report Number 2: Phakic Retinal Detachment Outcomes.

Ophthalmology 2020 Mar 9. Epub 2020 Mar 9.

Mid-Atlantic Retina, Philadelphia, Pennsylvania.

Purpose: Anatomically similar rhegmatogenous retinal detachments (RRDs) can be treated with scleral buckle (SB), pars plana vitrectomy (PPV), or SB combined with PPV (PPV/SB). This study compares moderately complex phakic primary RRD treated with SB, PPV, or PPV/SB to review anatomic and visual outcomes.

Design: Multicenter, retrospective, interventional cohort study. Read More

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http://dx.doi.org/10.1016/j.ophtha.2020.03.007DOI Listing

Critical analysis of techniques and materials used in devices, syringes, and needles used for intravitreal injections.

Prog Retin Eye Res 2020 Apr 18:100862. Epub 2020 Apr 18.

Department of Ophthalmology, Federal University of São Paulo, Rua Botucatu, 806, São Paulo, SP, Brazil; Department of Ophthalmology, SSM Health Saint Louis University Hospital, Saint Louis University, 1755, S. Grand Boulevard, Saint Louis, MO, USA.

Intravitreal injections have become the most commonly performed intraocular treatments worldwide. Because intravitreal injections may induce severe adverse events, such as infectious and noninfectious endophthalmitis, cataract, ocular hypertension, vitreous hemorrhage, or retinal detachment, appropriate awareness of the materials and techniques used are essential to reduce these sight-threatening complications. This review provides insights into the needles, syringes, silicone oil coating, sterilization methods, devices to assist intravitreal injections, scleral piercing techniques using needles, syringe handling, anesthesia, and safety issues related to materials and techniques. Read More

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http://dx.doi.org/10.1016/j.preteyeres.2020.100862DOI Listing
April 2020
8.733 Impact Factor

Demographic profile, clinical features, and outcome of peripapillary subretinal hemorrhage: an observational study.

BMC Ophthalmol 2020 Apr 19;20(1):156. Epub 2020 Apr 19.

Department of Ophthalmology, West China Hospital, Sichuan University, No. 37 Guoxue Lane, Chengdu, 610041, Sichuan, China.

Background: To evaluate the etiology, demographic profile, clinical features, and outcomes in patients with peripapillary subretinal hemorrhage (PSH).

Methods: Thirty-eight eyes of 37 consecutive patients with PSH were enrolled in this prospective observational study over 4 years; all were followed for 2 years. The main outcome measures were demographic profile, possible etiology, clinical features, outcome, and prognosis. Read More

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http://dx.doi.org/10.1186/s12886-020-01426-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168834PMC
April 2020
1.075 Impact Factor

Unusual presentation of early-onset X-linked retinoschisis: Report after 1 year of multimodal follow-up.

Eur J Ophthalmol 2020 Apr 20:1120672120916722. Epub 2020 Apr 20.

Department of Clinical Sciences and Community Health, Eye Clinic San Giuseppe Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Multimedica, University of Milan, Milan, Italy.

Purpose: To describe the unusual presentation, diagnosis, and clinical course of an early-onset X-linked infantile retinoschisis.

Case Report: A 6-month-old infant presented with strabismus and poor fixation. After the detection of bilateral intraretinal hemorrhage and diffuse dystrophic retinal pattern at indirect ophthalmoscopy, the patient received a complete evaluation under anesthesia. Read More

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http://dx.doi.org/10.1177/1120672120916722DOI Listing