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Neurohospitalist 2022 Jul 4;12(3):520-523. Epub 2022 Mar 4.

Neurology Department, Haseki Research and Training Hospital, University of Health Science, Istanbul, Turkey.

COVID-19 has been associated with central nervous system manifestations; however, cerebral venous thrombosis is rarely reported. A 34-year-old woman was admitted to the hospital with headache and recurrent seizures; she was recently discharged after COVID-19 pneumonia. Cranial magnetic resonance imaging and magnetic resonance venography showed cortical vein thrombosis in the right frontal lobe. Read More

Cureus 2022 May 19;14(5):e25150. Epub 2022 May 19.

Cardiology, Nicosia General Hospital, Nicosia, CYP.

Coronavirus disease 2019 (COVID-19) is a viral respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The respiratory system is the main target of the virus; however, apart from lung disease, a relatively large proportion of patients develop thrombosis as well. We present the case of a 19-year-old male who was admitted after contracting community-acquired right-sided pneumonia. Read More

Biosensors (Basel) 2022 Jun 13;12(6). Epub 2022 Jun 13.

Beijing Key Laboratory for Separation and Analysis in Biomedicine and Pharmaceuticals, School of Life Sciences, Beijing Institute of Technology, Beijing 100081, China.

The SARS-CoV-2 coronavirus, also known as the disease-causing agent for COVID-19, is a virulent pathogen that may infect people and certain animals. The global spread of COVID-19 and its emerging variation necessitates the development of rapid, reliable, simple, and low-cost diagnostic tools. Many methodologies and devices have been developed for the highly sensitive, selective, cost-effective, and rapid diagnosis of COVID-19. Read More

BMC Pulm Med 2022 Jun 22;22(1):243. Epub 2022 Jun 22.

Division of Intensive Care, Department of Anaesthesiology, Intensive Care and Pain Medicine, Helsinki University Hospital, Helsinki, Finland.

Background: The significant morbidity caused by COVID-19 necessitates further understanding of long-term recovery. Our aim was to evaluate long-term lung function, exercise capacity, and radiological findings in patients after critical COVID-19.

Methods: Patients who received treatment in ICU for COVID-19 between March 2020 and January 2021 underwent pulmonary function tests, a 6MWD and CXR 6 months after hospital discharge. Read More

Eur Rev Med Pharmacol Sci 2022 Jun;26(11):4123-4130

2nd Department of Radiology, Medical University of Lublin, Lublin, Poland.

Objective: There are studies discussing the lung CT abnormalities persisting 3-4 months after COVID-19 pneumonia. Very few studies have evaluated the radiological changes in longer perspective, especially in patients with a severe form of the disease. The aim of our study was to show and qualify the persistent CT changes and to evaluate the dynamics of their evolution in convalescent patients after discharge from hospital post moderate and severe COVID-19 pneumonia. Read More

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2022 May;34(5):509-513

Department of Emergency and Critical Care Medicine, the First People's Hospital of Lianyungang, Institute of Emergency Medicine of Lianyungang, Lianyungang 222000, Jiangsu, China.

Objective: To explore the diagnosis process and treatment experience of severe coronavirus disease 2019 (COVID-19) patients with heparin resistance (HR).

Methods: The medical team of the First People's Hospital of Lianyungang admitted 2 severe COVID-19 patients with HR in intensive care unit (ICU) during their support to the designated hospital for the treatment of COVID-19 patients in Lianyungang City in November 2021. The clinical features, laboratory examinations, imaging features, treatment and prognosis of the two patients were analyzed. Read More

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2022 May;34(5):492-496

Department of Critical Care Medicine, Xinjiang People's Hospital, Urumqi 830001, Xinjiang Uygur Autonomous Region, China. Corresponding author: Hu Rui, Email:

Objective: To analyze the treatment process of a renal transplant patient infected with coronavirus disease 2019 (COVID-19), and discuss the management strategy for the immunocompromised hosts.

Methods: The diagnosis and treatment of a case of transplant patients with COVID-19 admitted to Horgos designated hospital of Xinjiang Uygur Autonomous Region in October 2021 were reviewed. The medical history and laboratory and imaging examination treatment and outcome of this case were analyzed. Read More

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2022 May;34(5):485-491

Department of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (originally named "Shanghai First People's Hospital"), Shanghai 201620, China.

Objective: To compare and analyze the clinical features of patients with severe coronavirus disease 2019 (sCOVID-19) and severe community acquired pneumonia (sCAP) who meet the diagnostic criteria for severe pneumonia of the Infectious Diseases Society of America/American Thoracic Society (IDSA/ATS).

Methods: A retrospective comparative analysis of the clinical records of 116 patients with sCOVID-19 admitted to the department of critical care medicine of Wuhan Third Hospital from January 1, 2020 to March 31, 2020 and 135 patients with sCAP admitted to the department of critical care medicine of Shanghai First People's Hospital from January 1, 2010 to December 31, 2017 was conducted. The basic information, diagnosis and comorbidities, laboratory data, etiology and imaging results, treatment, prognosis and outcome of the patients were collected. Read More

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2022 May;34(5):459-464

Intensive Care Unit, the Third Central Hospital of Tianjin, Tianjin 300170, China.

Objective: To analyze the epidemiological and clinical characteristics of patients infected by novel coronavirus Omicron variant, and also to analyze whether vaccination against novel coronavirus has an impact on the severity and prognosis of Omicron patients.

Methods: A prospective, single-center observational study was conducted to collect data of consecutive patients with Omicron variant infection admitted to the designated hospital for coronavirus disease 2019 (COVID-19) charged by Tianjin COVID-19 rescue medical team of Tianjin Third Central Hospital, from January 8 to February 2, 2022. The clinical characteristics of the patients were analyzed, and the influence of whether the patients were inoculated with booster vaccination on the condition and outcome was analyzed. Read More

Pediatr Int 2022 Jan;64(1):e15198

Department of Pediatrics, Iwaki City Medical Center, Iwaki-shi, Japan.

Radiology 2022 Jul;304(1):241-244

From the Department of Radiology, University of Ottawa, 501 Smyth Rd, Ottawa, ON, Canada K1H 8L6 (N.R., O.H.A., C.H.T.), and Department of Medical Imaging, The Ottawa Hospital, Ottawa, Canada (O.H.A., C.H.T.).

History: A 54-year-old man was found by paramedics in his home face-down at his computer desk with a substantially reduced level of consciousness. He had not contacted his family for more than 50 hours. The patient lived alone and was a heavy smoker with a history of alcohol abuse. Read More

Curr Med Imaging 2022 Jun 20. Epub 2022 Jun 20.

Laboratory of Neuroimaging, USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

In 2019, a series of novel pneumonia cases later known as Coronavirus Disease 2019 (COVID-19) were reported in Wuhan, China. Chest computed tomography (CT) has played a key role in the management and prognostication in COVID-19 patients. CT has demonstrated 98% Methods: We conducted a comprehensive literature review of 17 published studies, including focuses on three subgroups, pediatric patients, pregnant women, and patients over 60 years old, to identify key characteristics of chest CT in COVID-19 patients. Read More

Ulster Med J 2022 May 15;91(2):79-84. Epub 2022 Jun 15.

General and Colorectal Surgical Unit, Ulster Hospital, Dundonald, Belfast, UK.

Background: The COVID-19 pandemic is an evolving healthcare challenge causing secondary disruption of cancer services. Quantitative Faecal Immunochemical Testing (qFIT) has been established as a screening method in asymptomatic patients. We aim to assess its utility as a triage tool to prioritise investigations in symptomatic patients with suspected colorectal cancer. Read More

Ups J Med Sci 2022 10;127. Epub 2022 May 10.

Neurology, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.

Background: Neurological and psychiatric manifestations related to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection are widely recognised. Standard magnetic resonance imaging (MRI) investigations are normal in 40-80% of symptomatic patients, eventually delaying appropriate treatment when MRI is unrevealing any structural changes. The aim of this study is to investigate white matter abnormalities during an early stage of post-COVID-19 (coronavirus disease 2019) encephalitis while conventional MRI was normal. Read More

World J Methodol 2022 May 20;12(3):83-91. Epub 2022 May 20.

Instituto Multidisciplinar em Saúde , Universidade Federal da Bahia, Vitória da Conquista 45029-094, Bahia, Brazil.

Coronavirus disease-19 (COVID-19) has become a pandemic, being a global health concern since December 2019 when the first cases were reported. Severe acute respiratory syndrome coronavirus 2, the COVID-19 causal agent, is a β-coronavirus that has on its surface the spike protein, which helps in its virulence and pathogenicity towards the host. Thus, effective and applicable diagnostic methods to this disease come as an important tool for the management of the patients. Read More

Comput Intell Neurosci 2022 16;2022:9414567. Epub 2022 Jun 16.

Department of Information Technology, College of Computer and Information Sciences, Princess Nourah bint Abdulrahman University, P.O.Box 84428, Riyadh 11671, Saudi Arabia.

COVID-19 has remained a threat to world life despite a recent reduction in cases. There is still a possibility that the virus will evolve and become more contagious. If such a situation occurs, the resulting calamity will be worse than in the past if we act irresponsibly. Read More

Front Public Health 2022 2;10:854977. Epub 2022 Jun 2.

Department of Neurology, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, China.

Background: The COVID-19 pandemic has a serious impact on the mental health of the public due to its economic and social impact. And psychological effects have led to drug and alcohol abuse. After the city lifted the lockdown, we consecutively encountered several young nitrous oxide abusers admitted to hospital for neurological treatment. Read More

Lancet 2022 06;399(10343):2263-2264

Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK; Department of Ageing and Health, Guys and St Thomas' NHS Foundation Trust, London, UK. Electronic address:

Sci Rep 2022 Jun 18;12(1):10297. Epub 2022 Jun 18.

SENAI-CIMATEC, Salvador, 41650 -010, Brazil.

We classify the main variants of the SARS-CoV-2 virus representing a given biological sequence coded as a symbolic digital sequence and by its evolution by a cellular automata with a properly chosen rule. The spike protein, common to all variants of the SARS-CoV-2 virus, is then by the picture of the cellular automaton evolution yielding a visible representation of important features of the protein. We use information theory Hamming distance between different stages of the evolution of the cellular automaton for seven variants relative to the original Wuhan/China virus. Read More

PET Clin 2022 Jul;17(3):533-542

Division of Diagnostic Nuclear Medicine, Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi 110029, India. Electronic address:

The role of nuclear medicine for noninvasive assessment of infection and inflammation is well established. The role of nuclear medicine is limited to initial diagnosis, recurrence, and response assessment of infections and inflammations such as tuberculosis, sarcoidosis, vasculitis, osteomyelitis, immunoglobulin G4-related diseases, and coronavirus disease 2019, as the specificity is affected by false positivity due to physiologic fluorodeoxyglucose uptake in specific organ and nonspecific uptake in postoperative cases. PET with fludeoxyglucose F 18/CT is a well-established modality for diagnosis of fever of unknown origin helping in optimized management of the patient. Read More

BMC Anesthesiol 2022 Jun 16;22(1):186. Epub 2022 Jun 16.

Department of Anesthesiology, Hospital Universitari Vall d'Hebron, Passeig de la Vall d'Hebron 119, 08035, Barcelona, Spain.

Background: For patients with a clinical course of active SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection, there may be a higher risk of perioperative complications. Our main objective is to detect the residual pulmonary alterations in asymptomatic patients after SARS-CoV-2 infection undergoing surgery and determine their relationship with the clinical course of SARS-CoV-2 infection. The secondary aim is to investigate whether the presence of residual pulmonary alterations have any affects on the severity of postoperative pulmonary complications. Read More

Clin Sports Med 2022 Jul 17;41(3):455-472. Epub 2022 Feb 17.

Emory University School of Medicine, Emory Clinical Cardiovascular Research Institute, 1462 Clifton Road, NE, Suite 502, Atlanta, GA 30311, USA.

Myocarditis is a leading cause of sudden death in athletes. Early data demonstrating increased prevalence of cardiac injury in hospitalized patients with COVID-19 raised concerns for athletes recovered from COVID-19 and the possibility of underlying myocarditis. However, subsequent large registries have provided reassuring data affirming low prevalence of myocarditis in athletes convalesced from COVID-19. Read More

PLoS One 2022 16;17(6):e0270111. Epub 2022 Jun 16.

Epidemiology Unit, AUSL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.

Background: COVID-19 prognostic factors include age, sex, comorbidities, laboratory and imaging findings, and time from symptom onset to seeking care.

Purpose: The study aim was to evaluate indices combining disease severity measures and time from disease onset to predict mortality of COVID-19 patients admitted to the emergency department (ED).

Materials And Methods: All consecutive COVID-19 patients who underwent both computed tomography (CT) and chest X-ray (CXR) at ED presentation between 27/02/2020 and 13/03/2020 were included. Read More

BMC Infect Dis 2022 Jun 15;22(1):548. Epub 2022 Jun 15.

Department of Medical Microbiology, University of Pretoria, Pretoria, South Africa.

Background: Human immunodeficiency virus (HIV) contributes significantly to morbidity and mortality in South Africa. Pneumonia and opportunistic infections remain a major cause for hospital admission among those living with HIV, even in the era of the widespread availability of antiretroviral therapy.

Methods: In this retrospective cohort study, the records of patients admitted with HIV and severe pneumonia, requiring high care/intensive care admission, during a period of 12 months (February 2018 to January 2019) were reviewed. Read More

S D Med 2022 Feb;75(2):62-64

Department of Cardiovascular Medicine, Sanford Hospital, Sioux Falls, South Dakota.

Background: Coronavirus disease 2019 (COVID-19) has become a leading cause of morbidity and mortality worldwide. One of the major complications of COVID-19 infection is the hypercoagulability state. Cardiac thrombi and venous thromboembolism (VTE) have been documented with severe COVID-19 infection. Read More

Am Fam Physician 2022 Jun;105(6):625-630

Rutgers University Robert Wood Johnson Medical School, New Brunswick, NJ, USA.

Community-acquired pneumonia (CAP) is a common condition with a hospitalization rate of about 2% in people 65 years or older and is associated with a 30-day mortality rate of 6% in hospitalized patients. In studies conducted before the COVID-19 pandemic, a bacterial pathogen was identified in 11% of patients, a viral pathogen in 23% of patients, and no organism in 62% of patients. Certain signs and symptoms can be helpful in diagnosing CAP and selecting imaging studies. Read More

Arq Bras Cardiol 2022 10;118(6):1141-1143. Epub 2022 Jun 10.

Departamento de Cirurgia Cardiovascular, Hospital da Cidade de Ancara, Ancara - Turquia.

New Microbiol 2022 04;45(2):115-123

Multi-Specialist Clinical Institute for Orthopaedic Trauma Care (COT), Messina, Italy

Infectious diseases still register significant morbidity and mortality worldwide. Surveillance through a mandatory notification system allows the continuous analysis of the situation even at a local level and its importance has been highlighted by the recent COVID-19 pandemic. This paper aimed to outline the importance of the mandatory notification system as a Public Health tool in the continuous monitoring of infectious diseases. Read More

BMJ Open 2022 Jun 13;12(6):e059110. Epub 2022 Jun 13.

Instituto do Coração-Divisão de Pneumologia, Universidade de São Paulo Hospital das Clínicas, Sao Paulo, Brazil.

Objective: This study aimed to propose a simple, accessible and low-cost predictive clinical model to detect lung lesions due to COVID-19 infection.

Design: This prospective cohort study included COVID-19 survivors hospitalised between 30 March 2020 and 31 August 2020 followed-up 6 months after hospital discharge. The pulmonary function was assessed using the modified Medical Research Council (mMRC) dyspnoea scale, oximetry (SpO), spirometry (forced vital capacity (FVC)) and chest X-ray (CXR) during an in-person consultation. Read More

Contrast Media Mol Imaging 2022 31;2022:6964283. Epub 2022 May 31.

Tuberculosis Department, Shanxi Linfen Third People's Hospital, Linfen City, Shanxi Province 041000, China.

Medical image classification technology, preferably which is based on the deep learning, is not only a key auxiliary diagnosis and treatment method in clinical medicine but also an important direction of scientific research. With the intensification of social aging, the incidence of viral elderly pneumonia has been on the rise and needs dedication from the research community. Doctors rely on personal theories and experience to use traditional methods to check the computed tomography (CT) images of the lungs of elderly patients one by one, which is likely to cause diagnosis errors. Read More