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    21466 results match your criteria Viral Hemorrhagic Fevers

    1 OF 430

    The Psychosocial Challenges of Caring for Patients with Ebola Virus Disease.
    Health Secur 2017 Jan/Feb;15(1):104-109
    Caring for highly infectious patients in biocontainment units is a new phenomenon, and little is known about the behavioral health of workers in this setting. This is a qualitative study exploring the unique experiences of workers involved in the care of patients with Ebola virus disease (EVD) at Nebraska Medicine during the 2014 Ebola outbreak. Twenty-one in-depth interviews were conducted focused on topics of personal memories, interpersonal experiences, stress response, and patient management. Read More

    Molecular docking based screening of compounds against VP40 from Ebola virus.
    Bioinformation 2016 15;12(3):192-196. Epub 2016 Jun 15.
    BioDiscovery Group, Agra, India.
    Ebola virus causes severe and often fatal hemorrhagic fevers in humans. The 2014 Ebola epidemic affected multiple countries. The virus matrix protein (VP40) plays a central role in virus assembly and budding. Read More

    A rare case of dengue encephalopathy complicating a term pregnancy.
    BMC Res Notes 2017 Feb 2;10(1):79. Epub 2017 Feb 2.
    Sri Jayewardenepura General Hospital, Sri Jayewardenepura, Kotte, Sri Lanka.
    Background: Dengue fever has an expanded clinical spectrum ranging from an asymptomatic infection to life threatening dengue hemorrhagic fever and refractory shock. Dengue infection in pregnancy can be a diagnostic dilemma, particularly considering the physiological changes in pregnancy and the obstetric complications encountered in clinical practice. Hence the knowledge of its diagnosis and management in its atypical presentations is of paramount importance. Read More

    Spatio-temporal analysis of the genetic diversity and complexity of Plasmodium falciparum infections in Kedougou, southeastern Senegal.
    Parasit Vectors 2017 Jan 19;10(1):33. Epub 2017 Jan 19.
    Institut Pasteur Dakar, Immunology Unit, 36 Avenue Pasteur, BP 220, Dakar, Senegal.
    Background: Genetic analyses of the malaria parasite population and its temporal and spatial dynamics could provide an assessment of the effectiveness of disease control strategies. The genetic diversity of Plasmodium falciparum has been poorly documented in Senegal, and limited data are available from the Kedougou Region. This study examines the spatial and temporal variation of the genetic diversity and complexity of P. Read More

    Antiviral effect of compounds derived from the seeds of Mammea americana and Tabernaemontana cymosa on Dengue and Chikungunya virus infections.
    BMC Complement Altern Med 2017 Jan 18;17(1):57. Epub 2017 Jan 18.
    Grupo de Investigación en Ciencias Animales-GRICA, Universidad Cooperativa de Colombia, Calle 30A # 33-51, Bucaramanga, Colombia.
    Background: The transmission of Dengue virus (DENV) and Chikungunya virus (CHIKV) has increased worldwide, due in part to the lack of a specific antiviral treatment. For this reason, the search for compounds with antiviral potential, either as licensed drugs or in natural products, is a research priority. The objective of this study was to identify some of the compounds that are present in Mammea americana (M. Read More

    Bilateral rectus sheath haematoma complicating dengue virus infection in a patient on warfarin for mechanical aortic valve replacement: a case report.
    BMC Res Notes 2017 Jan 7;10(1):26. Epub 2017 Jan 7.
    Internal Medicine, National Hospital of Sri Lanka, Colombo, Sri Lanka.
    Background: The management of Dengue virus infection can be challenging. Varied presentations and numerous complications intrinsic to dengue by itself increase the complexity of treatment and potential mortality. When burdened with the presence of additional comorbidities and the need to continue compulsory medications, clear stepwise definitive guidance is lacking and patients tend to have more complex complications and outcomes calling to question the clinical decisions that may have been taken. Read More

    High Triglycerides Are Associated with Low Thrombocyte Counts and High VEGF in Nephropathia Epidemica.
    J Immunol Res 2016 5;2016:8528270. Epub 2016 Dec 5.
    Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Tatarstan, Russia; University of Nevada, Reno, NV, USA.
    Nephropathia epidemica (NE) is a mild form of hemorrhagic fever with renal syndrome. Several reports have demonstrated a severe alteration in lipoprotein metabolism. However, little is known about changes in circulating lipids in NE. Read More

    Elevated thrombopoietin and platelet indices confirm active thrombopoiesis but fail to predict clinical severity of puumala hantavirus infection.
    Medicine (Baltimore) 2016 Dec;95(52):e5689
    aDepartment of Internal Medicine, Tampere University Hospital bSchool of Medicine, University of Tampere, Tampere cCoagulation Disorders Unit, Clinical Chemistry, HUSLAB Laboratory Services, Helsinki University Hospital dCoagulation Disorders Unit, Department of Hematology, Comprehensive Cancer Center, Helsinki University, and Helsinki University Hospital, Helsinki eSchool of Health Sciences, University of Tampere, Tampere fDepartment of Virology, Faculty of Medicine, University of Helsinki, Helsinki.
    We evaluated the mechanisms of thrombocytopenia and procoagulant changes in relation with clinical variables in a cohort of patients with acute hantavirus disease.Blood samples of 33 prospectively recruited, consecutive, hospitalized patients with acute Puumala virus-induced hemorrhagic fever with renal syndrome (HFRS) were collected acutely and at the recovery visit (control). Serum thrombopoietin (TPO) and activity of plasma microparticles (MPs) from various cell sources were measured with enzyme-linked immunosorbent assay-based methods. Read More

    Dengue Virus Serotypes Circulating in Khyber Pakhtunkhwa Province, Pakistan, 2013-2015.
    Ann Lab Med 2017 Mar;37(2):151-154
    Department of Virology, National Institute of Health, Park Road, Chak Shahzad, Islamabad, Pakistan.
    From 2013 to 2015, the National Institute of Health, Pakistan, received 1,270 blood samples of suspected dengue cases reported from inpatient and outpatient departments of various hospitals in Khyber Pakhtunkhwa (KPK) province. In this study, we determined the circulating dengue virus (DENV) serotypes using real-time reverse transcriptase (RT)-PCR to understand the serotype-based epidemiology of DENV. All four serotypes (DENV-1 [6%], DENV-2 [33%], DENV-3 [47%], and DENV-4 [0. Read More

    Ebola Virus Infection among Western Healthcare Workers Unable to Recall the Transmission Route.
    Biomed Res Int 2016 27;2016:8054709. Epub 2016 Nov 27.
    University College London, London, UK.
    Introduction. During the 2014-2016 West-African Ebola virus disease (EVD) outbreak, some HCWs from Western countries became infected despite proper equipment and training on EVD infection prevention and control (IPC) standards. Despite their high awareness toward EVD, some of them could not recall the transmission routes. Read More

    Merkel cell polyomavirus IgG antibody levels are associated with progression to AIDS among HIV-infected individuals.
    Arch Virol 2016 Dec 20. Epub 2016 Dec 20.
    Department of Virology, Iran University of Medical Sciences, Junction of Shahid Hemmat and Shahid Chamran Expressways, P.O. Box: 15785-6171, Tehran, 1449614535, Iran.
    The association of Merkel cell polyomavirus (MCPyV) with Merkel cell carcinoma (MCC) in immunocompromised individuals has been revealed in a number of surveys. The study of MCPyV specific antibody titers and viral loads in such patients has a great attraction for research groups interested in viral reactivation. In this cross-sectional study to evaluate MCPyV antibody titer, DNA prevalence and viral load in peripheral blood mononuclear cells (PBMCs), we examined 205 HIV-1 infected patients and 100 un-infected controls. Read More

    Comparison of N- and O-linked glycosylation patterns of ebolavirus glycoproteins.
    Virology 2017 Feb 13;502:39-47. Epub 2016 Dec 13.
    Center for Global Health, Division of Infectious Diseases, Department of Internal Medicine, University of New Mexico, Albuquerque, NM, USA. Electronic address:
    Ebolaviruses are emerging pathogens that cause severe and often fatal viral hemorrhagic fevers. Four distinct ebolaviruses are known to cause Ebola virus disease in humans. The ebolavirus envelope glycoprotein (GP1,2) is heavily glycosylated, but the precise glycosylation patterns of ebolaviruses are largely unknown. Read More

    Monitoring of Persons with Risk for Exposure to Ebola Virus - United States, November 3, 2014-December 27, 2015.
    MMWR Morb Mortal Wkly Rep 2016 Dec 16;65(49):1401-1404. Epub 2016 Dec 16.
    Division of State and Local Readiness, Office of Public Health Preparedness and Response, CDC.
    During November 3, 2014-December 27, 2015, CDC implemented guidance on movement and monitoring of persons in the United States with potential exposure to Ebola virus (Ebola) (1). Monitoring was concluded in December 2015. After CDC modified the guidance for monitoring travelers from Guinea (the last country for which monitoring of travelers was recommended) in late December 2015, jurisdictional reports were no longer collected by CDC. Read More

    Within-Host Evolution of Simian Arteriviruses in Crab-Eating Macaques.
    J Virol 2017 Feb 31;91(4). Epub 2017 Jan 31.
    Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, Wisconsin, USA
    Simian arteriviruses are a diverse clade of viruses infecting captive and wild nonhuman primates. We recently reported that Kibale red colobus virus 1 (KRCV-1) causes a mild and self-limiting disease in experimentally infected crab-eating macaques, while simian hemorrhagic fever virus (SHFV) causes lethal viral hemorrhagic fever. Here we characterize how these viruses evolved during replication in cell culture and in experimentally infected macaques. Read More

    Evaluation of a pan-serotype point-of-care rapid diagnostic assay for accurate detection of acute dengue infection.
    Diagn Microbiol Infect Dis 2017 Mar 30;87(3):229-234. Epub 2016 Sep 30.
    Division of Infectious Diseases, St. John's Research Institute, St. John's National Academy of Health Sciences, Bangalore, 560034, India; International Vaccine Access Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA. Electronic address:
    The catastrophic rise in dengue infections in India and globally has created a need for an accurate, validated low-cost rapid diagnostic test (RDT) for dengue. We prospectively evaluated the diagnostic performance of NS1/IgM RDT (dengue day 1) using 211 samples from a pediatric dengue cohort representing all 4 serotypes in southern India. The dengue-positive panel consisted of 179 dengue real-time polymerase chain reaction (RT-PCR) positive samples from symptomatic children. Read More

    RT-PCR using glycoprotein target is more sensitive for the detection of Ebola virus in clinical samples.
    Diagn Microbiol Infect Dis 2017 Mar 5;87(3):235-237. Epub 2016 Nov 5.
    Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, 100071, China; Key Laboratory of Zoonosis of Liaoning Province, College of Animal Science and Veterinary Medicine, Shenyang Agriculture University, 110866, Shenyang, China; China Mobile Laboratory Response Team for Ebola in Sierra Leone, Freetown, Sierra Leone. Electronic address:
    The recent largest ever Ebola virus disease (EVD) outbreak in West Africa has been of worldwide concern, causing huge economic losses and constituting serious threat to the local residents and health care workers. Rapid detection of Ebola virus (EBOV) using RT-PCR has been suggested to be of great value in stopping the outbreak, because it is highly sensitive and specific and can return results within hours. In this study, 210 clinical samples, including 109 blood and 101 nasopharyngeal swab samples were used to compare the performance of glycoprotein (GP) and nucleoprotein (NP) gene targets for the detection of EBOV. Read More

    The exploration of risk factors of concurrent bacteraemia in patients critically ill with severe dengue.
    J Med Microbiol 2016 Dec 7;65(12):1505-1511. Epub 2016 Nov 7.
    2​Department of Intensive Care Medicine, Chi-Mei Medical Center, Tainan, Taiwan, ROC 5​Department of Medicine, Taipei Medical University, Taipei, Taiwan, ROC.
    We investigated the clinical features of intensive care unit (ICU) patients with concomitant severe dengue infection and bacteraemia to identify risk factors for this comorbidity. The records of all ICU dengue patients admitted during the period of 31 July-30 November 2015 were reviewed. Patients with 'concurrent bacteremia' (positive bacterial blood culture within 72 h of ICU admission) were identified. Read More

    Four weeks of paritaprevir/ritonavir/ombitasvir plus dasabuvir encountering dengue fever resulted in sustained virological response in an HCV patient: A case report.
    Medicine (Baltimore) 2016 Nov;95(47):e5304
    aHepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University bFaculty of Internal Medicine, College of Medicine, Center for Infectious Disease and Cancer Research, Lipid Science and Aging Research Center, Kaohsiung Medical University cDepartment of Occupational Medicine, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University dDepartment of Laboratory Medicine, and Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University eInstitute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung fHealth Management Center, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University, Taiwan.
    Background: Direct antiviral agent (DAA) has been the standard of care for patients with hepatitis C virus (HCV) infection. Twelve weeks of paritaprevir/ritonavir/ombitasvir plus dasabuvir (PROD) with or without ribavirin has shown to have a sustained virological response at post-treatment 12 weeks (SVR12) rate of >90% in HCV genotype 1 (HCV-1) patients.

    Methods: We report a HCV-1b patient who received only 25 days of PROD treatment. Read More

    Fern-synthesized silver nanocrystals: Towards a new class of mosquito oviposition deterrents?
    Res Vet Sci 2016 Dec 17;109:40-51. Epub 2016 Sep 17.
    Insect Behavior Group, Department of Agriculture, Food and Environment, University of Pisa, via del Borghetto 80, 56124 Pisa, Italy. Electronic address:
    Mosquitoes act as vectors of devastating pathogens and parasites, representing a key threat for millions of humans and animals worldwide. Eco-friendly control tools are urgently required. We proposed a novel method of fern-mediated biosynthesis of silver nanoparticles (AgNP) using Dicranopteris linearis, acting as a reducing and capping agent. Read More

    Mild encephalitis/encephalopathy with reversible splenial lesion (MERS) due to dengue virus.
    J Clin Neurosci 2017 Feb 23;36:73-75. Epub 2016 Nov 23.
    Biomedical Imaging Department, University of Malaya Medical Centre, Kuala Lumpur, Malaysia.
    A 14-year-old girl presented with encephalopathy, delirium and ophthalmoplegia following a 3day history of high-grade fever. Brain MRI on day 6 of illness showed diffusion restricted ovoid lesion in the splenium of corpus callosum. Dengue virus encephalitis was diagnosed with positive PCR for dengue virus type-2 in both serum and cerebrospinal fluid. Read More

    Notice to Readers: Final 2015 Reports of Nationally Notifiable Infectious Diseases and Conditions.
    • Authors:
    MMWR Morb Mortal Wkly Rep 2016 Nov 25;65(46):1306-1321. Epub 2016 Nov 25.
    The table listed in this report on pages 1307-1321 presents finalized data, as of June 30, 2016, from the National Notifiable Diseases Surveillance System (NNDSS) for 2015. These data will be published in more detail in the Summary of Notifiable Infectious Diseases and Conditions - United States, 2015 (1). Because no cases were reported in the United States during 2015, the following diseases do not appear in this early release table: anthrax; dengue hemorrhagic fever; diphtheria; eastern equine encephalitis virus disease, nonneuroinvasive; poliomyelitis, paralytic; poliovirus infection, nonparalytic; severe acute respiratory syndrome-associated coronavirus disease (SARS-CoV); smallpox; western equine encephalitis virus disease, neuroinvasive and nonneuroinvasive; yellow fever; and viral hemorrhagic fevers. Read More

    Crimean-Congo hemorrhagic fever among children in Iran.
    Arch Virol 2016 Nov 22. Epub 2016 Nov 22.
    Department of Arboviruses and Viral Hemorrhagic Fevers (National Ref Lab), Pasteur Institute of Iran, 69 Pasteur Ave., Tehran, 1316943551, Iran.
    Crimean-Congo hemorrhagic fever (CCHF) is a viral zoonotic disease which is endemic in Iran. The etiological agent of CCHF is an RNA virus belonging to the genus Nairovirus of the family Bunyaviridae. CCHF virus (CCHFV) can be transmitted to humans through bites from infected ticks and direct contact with infected blood or tissues. Read More

    Trend and geographic analysis of the prevalence of dengue in Taiwan, 2010-2015.
    Int J Infect Dis 2017 Jan 16;54:43-49. Epub 2016 Nov 16.
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts, USA.
    Background: Dengue is the most rapidly spreading disease caused by a mosquito-borne virus in the world. The incidence of dengue globally has increased 30-fold in the last 50 years. Understanding the prevalence of dengue and its longitudinal trends can improve prevention and control strategies. Read More

    Dynamic expression of genes encoding subunits of inward rectifier potassium (Kir) channels in the yellow fever mosquito Aedes aegypti.
    Comp Biochem Physiol B Biochem Mol Biol 2017 Feb 9;204:35-44. Epub 2016 Nov 9.
    Department of Entomology, Ohio Agricultural Research and Development Center, The Ohio State University, Wooster, OH, United States. Electronic address:
    Inward rectifier potassium (Kir) channels play fundamental roles in neuromuscular, epithelial, and endocrine function in mammals. Recent research in insects suggests that Kir channels play critical roles in the development, immune function, and excretory physiology of fruit flies and/or mosquitoes. Moreover, our group has demonstrated that mosquito Kir channels may serve as valuable targets for the development of novel insecticides. Read More

    Dengue serotype-specific seroprevalence among 5- to 10-year-old children in India: a community-based cross-sectional study.
    Int J Infect Dis 2017 Jan 4;54:25-30. Epub 2016 Nov 4.
    Sanofi Pasteur Asia & JPAC Region, Singapore.
    Background: Dengue surveillance data in India are limited and probably substantially underestimate the burden of disease. A community-based study was undertaken to assess the prevalence of dengue-specific immunoglobulin G (IgG) antibodies in children across India and to examine historical dengue exposure rates. Potential associations between socio-economic factors and dengue seroprevalence were also assessed (registered at ctri. Read More

    Mosquito-transmitted viruses - the great Brazilian challenge.
    Braz J Microbiol 2016 Dec 27;47 Suppl 1:38-50. Epub 2016 Oct 27.
    Faculdade de Medicina de São José do Rio Preto (FAMERP), São José do Rio Preto, SP, Brazil. Electronic address:
    Arboviruses pose a serious threat to public health worldwide, overloading the healthcare system and causing economic losses. These viruses form a very diverse group, and in Brazil, arboviruses belonging to the families Flaviviridae and Togaviridae are predominant. Unfortunately, the number of arboviruses increases in proportion with factors such as deforestation, poor sanitation, climate changes, and introduction of new viruses like Chikungunya virus and Zika virus. Read More

    Acute pancreatitis complicating dengue hemorrhagic fever.
    Rev Soc Bras Med Trop 2016 Sep-Oct;49(5):656-659
    Department of Pediatrics, Jagadguru Sri Shivarathreeswara Medical College, Jagadguru Sri Shivarathreeswara University, Mysore, India.
    Dengue infection can have spectrum of manifestations, often with an unpredictable clinical progression and outcome. There have been increasing reports of atypical manifestations. Abdominal pain or tenderness and persistent vomiting (warning signs) are present in the majority of cases with severe dengue prior to clinical deterioration. Read More

    Notes from the Field: Rift Valley Fever Response - Kabale District, Uganda, March 2016.
    MMWR Morb Mortal Wkly Rep 2016 Nov 4;65(43):1200-1201. Epub 2016 Nov 4.
    On March 9, 2016, a male butcher from Kabale District, Uganda, aged 45 years, reported to the Kabale Regional Referral Hospital with fever, fatigue, and headache associated with black tarry stools and bleeding from the nose. One day later, a student aged 16 years from a different sub-county in Kabale District developed similar symptoms and was admitted to the same hospital. The student also had a history of contact with livestock. Read More

    Cannabidiol: a potential treatment for post Ebola syndrome?
    Int J Infect Dis 2016 Nov 26;52:74-76. Epub 2016 Sep 26.
    Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York, USA. Electronic address:
    Patients recovered from Ebola virus infection may experience short- and long-term physical, neuropsychological and social sequelae, including arthralgia, musculoskeletal pain, ophthalmic inflammation, auditory problems, fatigue, confusion, insomnia, short-term memory impairment, anxiety, depression and anorexia, all lasting from two weeks to more than two years. Currently there are no treatments for post Ebola sequelae. We hypothesize that cannabidiol (CBD) may attenuate some of these post Ebola sequelae, several of which have been postulated to result from inflammation and/or an autoimmune response. Read More

    Clinical presentations and outcomes of patients with Ebola virus disease in Freetown, Sierra Leone.
    Infect Dis Poverty 2016 Nov 3;5(1):101. Epub 2016 Nov 3.
    Chinese Military Medical Aid Team in Sierra Leone, The Beijing 302 Hospital, 100 XI-SIHUAN Middle Road, Beijing, 100039, China.
    Background: Clinical and laboratory data were collected and analysed from patients with Ebola virus disease (EVD) in Jui Government Hospital in Freetown, Sierra Leone, where patients with EVD were received and/or treated from October 1, 2014 to March 21, 2015 during the West Africa EVD outbreak.

    Methods: The study admitted 285 patients with confirmed EVD and followed them up till the endpoint (recovery or death). EVD was confirmed by quantitative RT-PCR assays detecting blood Ebola virus (EBOV). Read More

    Comparison of MagPix Assays and Enzyme-Linked Immunosorbent Assay for Detection of Hemorrhagic Fever Viruses.
    J Clin Microbiol 2017 Jan 28;55(1):68-78. Epub 2016 Dec 28.
    Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Maryland, USA
    Viral hemorrhagic fevers, because of their high mortality rates, the lack of medical countermeasures, and their potential use as instruments of bioterrorism, pose a significant threat to the developed and the developing areas of the world. The key to preventing the spread of these diseases is early and accurate detection. For decades, the gold-standard immunoassay for hemorrhagic fever detection has been the enzyme-linked immunosorbent assay (ELISA); however, newer technologies are emerging with increased sensitivities. Read More

    Aedes (Stegomyia) albopictus' dynamics influenced by spatiotemporal characteristics in a Brazilian dengue-endemic risk city.
    Acta Trop 2016 Dec 19;164:431-437. Epub 2016 Oct 19.
    Medical Entomology Laboratory, René Rachou Research Centre - FIOCRUZ-MG, Avenue Augusto de Lima, 1715, Barro Preto, Belo Horizonte, Minas Gerais, 30190-002, Brazil. Electronic address:
    Brazil reported the majority of the dengue cases in Americas during the last two decades, where the occurrence of human dengue cases is exclusively attributed to the Aedes (Stegomyia) aegypti (Linnaeus). Nowadays, other recognized Dengue virus (DENV) vector in Asian countries, Aedes (Stegomyia) albopictus (Skuse), has been detected in more than half of the 5565 Brazilian municipalities. Therefore, the aim of the present study was to investigate the presence of, and determine the Ae. Read More

    Characterization of the Glycoprotein Stable Signal Peptide in Mediating Pichinde Virus Replication and Virulence.
    J Virol 2016 Nov 28;90(22):10390-10397. Epub 2016 Oct 28.
    Department of Veterinary and Biomedical Sciences, University of Minnesota, Twin Cities, Minnesota, USA
    Arenaviruses can cause lethal hemorrhagic fevers in humans with few preventative and therapeutic measures. The arenaviral glycoprotein stable signal peptide (SSP) is unique among signal peptides in that it is an integral component of the mature glycoprotein complex (GPC) and plays important roles not only in GPC expression and processing but also in the membrane fusion process during viral entry. Using the Pichinde virus (PICV) reverse genetics system, we analyzed the effects of alanine substitutions at many conserved residues within the SSP on viral replication in cell culture and in a guinea pig infection model. Read More

    A spatial model of socioeconomic and environmental determinants of dengue fever in Cali, Colombia.
    Acta Trop 2016 Dec 9;164:169-176. Epub 2016 Sep 9.
    School of History and Social Sciences, Louisiana Tech University, Ruston, LA, 71272, USA, USA.
    Dengue fever has gradually re-emerged across the global South, particularly affecting urban areas of the tropics and sub-tropics. The dynamics of dengue fever transmission are sensitive to changes in environmental conditions, as well as local demographic and socioeconomic factors. In 2010, the municipality of Cali, Colombia, experienced one of its worst outbreaks, however the outbreak was not spatially homogeneous across the city. Read More

    Dengue virus surveillance: Detection of DENV-4 in the city of São José do Rio Preto, SP, Brazil.
    Acta Trop 2016 Dec 5;164:84-89. Epub 2016 Sep 5.
    Faculdade de Medicina de São José do Rio Preto (FAMERP), São José do Rio Preto, SP, Brazil. Electronic address:
    Dengue viruses are the most common arbovirus infection worldwide and are caused by four distinct serotypes of the dengue virus (DENV). In the present study, we assessed DENV transmission in São José do Rio Preto (SJRP) from 2010 to 2014. We analyzed blood samples from febrile patients who were attended at health care centers in SJRP. Read More

    Non-human primate antibody response to mosquito salivary proteins: Implications for dengue virus transmission in Puerto Rico.
    Acta Trop 2016 Dec 2;164:369-374. Epub 2016 Sep 2.
    Dengue Branch, Centers for Disease Control and Prevention, San Juan 00920, Puerto Rico. Electronic address:
    An important step to incriminate a mosquito as a vector of a disease pathogen is finding evidence of direct contact between the mosquito and humans. Typically, this is accomplished through landing/biting catches, or host blood meal analysis in engorged mosquitoes via immunologic assays. An alternate approach is to identify the presence of specific mosquito anti-saliva protein antibodies in the blood of exposed hosts. Read More

    Infectious diseases in Poland in 2014
    Przegl Epidemiol 2016;70(2):167-181
    National Institute of Public Health - National Institute of Hygiene in Warsaw, Department of Epidemiology
    Purpose Of The Study: The aim of the study is to assess epidemiological situation of infectious and parasitic diseases in Poland in 2014, and an indication of the potential health risks from communicable diseases occurring in other areas of the globe.

    Material And Methods: This paper is a summary of the analysis and evaluation of the results of epidemiological surveillance of infectious diseases in Poland in 2014, and those elements of European and global epidemiological background, which in this period had an impact on the epidemiological situation in Poland or constituted a threat. The main source of data for this study are statistical reports included in annual bulletins “Infectious diseases and poisoning in Poland in 2014” and “Immunizations in Poland in 2014” (NIPH-PZH, GIS, Warsaw 2015) and the data contained in the articles of „Epidemiological chronicle” presented in the Data on deaths are based on the statement of the Department for Demographic Research and Labour Market CSO presenting numbers of deaths from infectious and parasitic diseases registered in Poland in 2014, and in the previous years. Read More

    Plasmablasts During Acute Dengue Infection Represent a Small Subset of a Broader Virus-specific Memory B Cell Pool.
    EBioMedicine 2016 Oct 7;12:178-188. Epub 2016 Sep 7.
    Singapore Immunology Network, A*STAR, Singapore. Electronic address:
    Dengue is endemic in tropical countries worldwide and the four dengue virus serotypes often co-circulate. Infection with one serotype results in high titers of cross-reactive antibodies produced by plasmablasts, protecting temporarily against all serotypes, but impairing protective immunity in subsequent infections. To understand the development of these plasmablasts, we analyzed virus-specific B cell properties in patients during acute disease and at convalescence. Read More

    Identifying Areas Suitable for the Occurrence of Rift Valley Fever in North Africa: Implications for Surveillance.
    Transbound Emerg Dis 2016 Dec 6;63(6):658-674. Epub 2015 Feb 6.
    Unité Epidémiologie, Laboratoire de Lyon, Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), Lyon, France.
    Rift Valley fever (RVF) is a vector-borne zoonotic disease that has caused widespread outbreaks throughout Africa and the Arabian Peninsula, with serious consequences for livestock-based economies and public health. Although there have never been any reports of RVF in Morocco, Algeria, Tunisia and Libya, it is a priority disease in the Maghreb, due to the threat of introduction of the virus through transboundary livestock movements or infected mosquito vectors. However, the implementation of surveillance activities and early warning contingency plans requires better knowledge of the epidemiological situation. Read More

    The Ebola Virus VP30-NP Interaction Is a Regulator of Viral RNA Synthesis.
    PLoS Pathog 2016 Oct 18;12(10):e1005937. Epub 2016 Oct 18.
    Department of Immunology and Microbial Sciences, The Scripps Research Institute, La Jolla, California, United States of America.
    Filoviruses are capable of causing deadly hemorrhagic fevers. All nonsegmented negative-sense RNA-virus nucleocapsids are composed of a nucleoprotein (NP), a phosphoprotein (VP35) and a polymerase (L). However, the VP30 RNA-synthesis co-factor is unique to the filoviruses. Read More

    Risk of transmission of viral haemorrhagic fevers and the insecticide susceptibilitystatus of aedes aegypti (linnaeus) in some sites in Accra, Ghana.
    Ghana Med J 2016 Sep;50(3):136-141
    Noguchi Memorial Institute for Medical Research, Dept. of Parasitology, Legon, Accra, Ghana.
    Background: Dengue is one of the emerging diseases that can mostly only be controlled by vector control since there is no vaccine for the disease. Although, Dengue has not been reported in Ghana, movement of people from neighbouring countries where the disease has been reported can facilitate transmission of the disease.

    Objective: This study was carried on the University of Ghana campus to determine the risk of transmission of viral haemorrhagic fevers and the insecticide susceptibility status of Ae. Read More

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