14,336 results match your criteria Vibrio Infections

Characterization of Prophylactic Antimicrobial Therapy Practices for Patients With Marine-Associated Injuries in the Emergency Department.

J Pharm Pract 2021 Jun 8:8971900211021058. Epub 2021 Jun 8.

College of Pharmacy, 2629University of South Carolina, Columbia, SC, USA.

Background: Centers for Disease Control and Prevention (CDC) recommendations for the treatment of marine-associated wound infections include empiric coverage for species with a combination of a third-generation cephalosporin and doxycycline. These recommendations are based on limited data and it remains unclear if this regimen is also indicated for prophylaxis.

Objective: The purpose of this analysis was to assess the antibiotic regimens used in the emergency department (ED) for prophylaxis of marine-associated injuries relative to the CDC recommendations and evaluate any clinical impact. Read More

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Biofilm inhibitory effect of alginate lyases on mucoid from a cystic fibrosis patient.

Biochem Biophys Rep 2021 Jul 26;26:101028. Epub 2021 May 26.

CSIR- Institute of Microbial Technology, Sector 39A, Chandigarh, 160036, India.

Chronic mucoid infections are a major scourge in cystic fibrosis patients. Mucoid displays structured alginate-rich biofilms that are resistant to antibiotics. Here, we have assessed the efficacy of a panel of alginate lyases in combating mucoid biofilms in cystic fibrosis. Read More

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Wiad Lek 2021 ;74(5):1241-1244


Objective: The aim: The aim of the research is to determine and systematize administrative and medical measures aimed at curbing cholera in the city of Kharkiv in the time of the Russian Empire, to assess the relevance of the experience in fighting the disease, to determine the impact of epidemics and anti-epidemic measures on Kharkiv residents' public health.

Patients And Methods: Materials and methods: General scientific and specific historical methods were used, and methods of related sciences were applied as well. The main methods of historical research included, in particular, historical analytical, chronological and comparative historical; methods of medical statistics, etc. Read More

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Outer Membrane Vesicles of Vibrio cholerae Protect and Deliver Active Cholera Toxin to Host Cells via Porin-Dependent Uptake.

mBio 2021 May 26:e0053421. Epub 2021 May 26.

Institute of Molecular Biosciences, University of Graz, Graz, Austria.

Outer membrane vesicles (OMVs) are an emerging research field due to their multifactorial composition and involvement in interspecies and intraspecies communication. Recent studies indicate that vesicle release by Gram-negative bacterial pathogens is increased during colonization, as exemplified by the facultative human pathogen Vibrio cholerae upon oral ingestion by the host. In this study, we investigate the fate of OMVs produced by the Gram-negative facultative pathogen V. Read More

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Prevalence and Antibiogram of and in the Flesh of Nile Tilapia, with Special Reference to Their Virulence Genes Detected Using Multiplex PCR Technique.

Antibiotics (Basel) 2021 May 30;10(6). Epub 2021 May 30.

Department of Biology, College of Science in Zulfi, Majmaah University, Majmaah 11952, Saudi Arabia.

and are major public health problems and the main cause of bacterial disease in Nile tilapia (). This study was conducted to determine the prevalence, antibiotic resistance and some virulence genes of both and isolates from Nile tilapia. From Manzala Farm at Dakahlia governorate, 250 freshwater fish samples were collected. Read More

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A Markerless Gene Deletion System in by Using the Copper-Inducible YoeB Toxin as a Counterselectable Marker.

Microorganisms 2021 May 19;9(5). Epub 2021 May 19.

College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.

is an important zoonotic pathogen causing severe infections in swine and humans. Induction of the YoeB toxin in resulted in cell death, leading to the speculation that YoeB can be a counterselectable marker. Herein, the counterselection potential of YoeB was assessed in . Read More

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Duplex On-Site Detection of and by Recombinase Polymerase Amplification and Three-Segment Lateral Flow Strips.

Biosensors (Basel) 2021 May 12;11(5). Epub 2021 May 12.

Key Laboratory of Molecular Biophysics of Ministry of Education, Department of Biomedical Engineering, College of Life Science and Technology, Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan 430074, China.

and are two most reported foodborne pathogens related to seafood. Due to global ocean warming and an increase in seafood consumption worldwide, foodborne illnesses related to infection of these two bacteria are growing, leading to food safety issues and economic consequences. Molecular detection methods targeting species-specific genes are effective tools in the fight against bacterial infections for food safety. Read More

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Sequencing Provides Insights Into the Pathogenicity of Foodborne .

Front Cell Infect Microbiol 2021 14;11:652957. Epub 2021 May 14.

Central Laboratory, The Sixth Medical Centre, Chinese PLA (People's Liberation Army) General Hospital, Beijing, China.

is a common pathogenic marine bacterium that causes gastrointestinal infections and other health complications, which could be life-threatening to immunocompromised patients. For the past two decades, the pathogenicity of environmental has increased greatly, and the genomic change behind this phenomenon still needs an in-depth exploration. To investigate the difference in pathogenicity at the genomic level, three strains with different hemolysin expression and biofilm formation capacity were screened out of 69 environmental strains. Read More

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Outbreak of vibriosis associated with Vibrio parahaemolyticus in the mud crab Scylla paramamosain cultured in China.

Dis Aquat Organ 2021 May 27;144:187-196. Epub 2021 May 27.

School of Marine Sciences, Ningbo University, Ningbo, Zhejiang Province 315832, PR China.

In this study, a Gram-negative bacterium was isolated from diseased Scylla paramamosain and tentatively named strain QX17. The bacterial isolate was identified as Vibrio parahaemolyticus based on morphological and biochemical characteristics and molecular identification with the 16S rRNA and HSP60 genes. In the challenge experiment, S. Read More

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Protection afforded by previous Vibrio cholerae infection against subsequent disease and infection: A review.

PLoS Negl Trop Dis 2021 May 20;15(5):e0009383. Epub 2021 May 20.

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.

Background: Cholera is an acute, diarrheal disease caused by Vibrio cholerae O1 or 139 that is associated with a high global burden.

Methods: We analyzed the estimated duration of immunity following cholera infection from available published studies. We searched PubMed and Web of Science for studies of the long-term immunity following cholera infection. Read More

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Application of MALDI-TOF MS Profiling Coupled With Functionalized Magnetic Enrichment for Rapid Identification of Pathogens in a Patient With Open Fracture.

Front Chem 2021 30;9:672744. Epub 2021 Apr 30.

Key Laboratory of Advanced Mass Spectrometry and Molecular Analysis of Zhejiang Province, Institute of Mass Spectrometry, School of Material Science and Chemical Engineering, Ningbo University, Ningbo, China.

Posttraumatic infections can occur in orthopedic trauma patients, especially in open fractures. Rapid and accurate identification of pathogens in orthopedic trauma is important for clinical diagnosis and antimicrobial treatment. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has been successfully used for first-line identification of pathogens grown on culture plates. Read More

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Influence of Community-Led Total Sanitation and Water Coverages in the Control of Cholera in Madarounfa, Niger (2018).

Front Public Health 2021 29;9:643079. Epub 2021 Apr 29.

Centre for Research on the Ecology and Evolution of Diseases (CREES), Montpellier, France.

Every year, cholera affects 1.3-4.0 million people worldwide with a particularly high presence in Africa. Read More

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TolCV1 Has Multifaceted Roles During Infection.

Front Cell Infect Microbiol 2021 30;11:673222. Epub 2021 Apr 30.

College of Pharmacy and Research Institute of Drug Development, Chonnam National University, Gwangju, South Korea.

RtxA1 is a major cytotoxin of () causing fatal septicemia and necrotic wound infections. Our previous work has shown that RpoS regulates the expression and secretion of RtxA1 toxin. This study was conducted to further investigate the potential mechanisms of RpoS on RtxA1 secretion. Read More

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Implication of the Type IV Secretion System in the Pathogenicity of , the Etiological Agent of Brown Ring Disease Affecting the Manila Clam .

Front Cell Infect Microbiol 2021 29;11:634427. Epub 2021 Apr 29.

Univ Brest, CNRS, IRD, Ifremer, UMR 6539 LEMAR, Plouzane, France.

is a Gram-negative bacterium that causes infections of mollusk bivalves and fish. The Brown Ring Disease (BRD) is an infection caused by that primarily affects the Manila clam . Recent studies have shown that a type IV secretion system (T4SS) gene cluster is exclusively found in strains of pathogenic to clams. Read More

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Reduced virulence of the MARTX toxin increases the persistence of outbreak-associated Vibrio vulnificus in host reservoirs.

J Biol Chem 2021 May 13:100777. Epub 2021 May 13.

Infection and Immunity Research Laboratory, Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Korea. Electronic address:

Opportunistic bacteria strategically dampen their virulence to allow them to survive and propagate in hosts. However, the molecular mechanisms underlying virulence control are not clearly understood. Here, we found that the opportunistic pathogen Vibrio vulnificus biotype 3, which caused an outbreak of severe wound and intestinal infections associated with farmed tilapia, secretes significantly less virulent multifunctional autoprocessing repeats-in-toxin (MARTX) toxin, which is the most critical virulence factor in other clinical Vibrio strains. Read More

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Prognostic Factors of Mortality in Sepsis and Soft Tissue Infections: Meta-Analysis.

Surg Infect (Larchmt) 2021 May 7. Epub 2021 May 7.

Tulane University, New Orleans, Louisiana, USA.

is a rare but life-threatening infection that effects the population near warm coastal areas. This infection could be fulminant and rapidly progress to severe sepsis and necrotizing soft tissue infection. Early diagnosis and treatment are critical to saving patients' lives. Read More

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Susceptibility variation to the main pathogens of Crassostrea gigas at the larval, spat and juvenile stages using unselected and selected oysters to OsHV-1 and/or V. aestuarianus.

J Invertebr Pathol 2021 May 5;183:107601. Epub 2021 May 5.

IHPE, Université de Montpellier, CNRS, Ifremer, Université de Perpignan Via Domitia, F-34090 Montpellier, France.

French commercial hatcheries are massively producing Crassostrea gigas selected for their higher resistance to OsHV-1, and soon should also implement selection for increasing resistance to Vibrio aestuarianus. The first objective of this study was to optimize the breeding programs for dual resistance to OsHV-1 and V. aestuarianus to determine the earliest life stage for which oysters are able to develop disease resistance. Read More

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Presence, seasonal distribution and biomolecular characterization of Vibrio parahaemolyticus and Vibrio vulnificus in shellfish harvested and marketed in Sardinia (Italy) between 2017 and 2018.

J Food Prot 2021 May 6. Epub 2021 May 6.

University of Sassari: Universita degli Studi di Sassari Veterinary Medicine Via Vienna 2 ITALY Sassari SS 07100 +393493726552.

In the present study, we aimed to investigate the presence, seasonal distribution and biomolecular characterization of Vibrio parahaemolyticus and Vibrio vulnificus in samples of bivalve molluscs ( Mytilus galloprovincialis, Crassostrea gigas, Ruditapes decussatus, Venus verrucosa and Solen vagina ) and gastropod molluscs (Murex brandaris) harvested and marketed in Sardinia (Italy) between 2017 and 2018. A total of 444 samples were submitted to qualitative determination of Vibrio spp., V. Read More

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pH-Controlled Release of Antigens Using Mesoporous Silica Nanoparticles Delivery System for Developing a Fish Oral Vaccine.

Front Immunol 2021 19;12:644396. Epub 2021 Apr 19.

Provincial University Key Laboratory of Cellular Stress Response and Metabolic Regulation, College of Life Science, Fujian Normal University, Fuzhou, China.

The development of effective vaccines and delivery systems in aquaculture is a long-term challenge for controlling emerging and reemerging infections. Cost-efficient and advanced nanoparticle vaccines are of tremendous applicability in prevention of infectious diseases of fish. In this study, dihydrolipoamide dehydrogenase (DLDH) antigens of were loaded into mesoporous silica nanoparticles (MSN) to compose the vaccine delivery system. Read More

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Prevalence, Genetic Diversity, Antimicrobial Resistance, and Toxigenic Profile of Isolated from Aquatic Environments in Taiwan.

Antibiotics (Basel) 2021 Apr 29;10(5). Epub 2021 Apr 29.

Department of Internal Medicine, National Cheng Kung University Hospital, Tainan 704, Taiwan.

is a gram-negative, opportunistic human pathogen associated with life-threatening wound infections and is commonly found in warm coastal marine water environments, globally. In this study, two fishing harbors and three tributaries of the river basin were analyzed for the prevalence of in the water bodies and shellfish that are under the pressure of external pollutions. The average detection rate of in the river basins and fishing harbors was 8. Read More

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Barbel steed (Hemibarbus labeo) NK-lysin protects against Aeromonas hydrophila infection via immunomodulatory activity.

Dev Comp Immunol 2021 Sep 1;122:104114. Epub 2021 May 1.

College of Ecology, Lishui University, Lishui, 323000, China.

NK-lysins (NKLs) are a family of multifunctional antimicrobial peptides that have activity against various microorganisms. However, the immunomodulatory activity of NKL in fish remains unclear. In this study, the cDNA sequence of barbel steed (Hemibarbus labeo) NKL gene was cloned. Read More

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September 2021

Succinate Promotes Phagocytosis of Monocytes/Macrophages in Teleost Fish.

Front Mol Biosci 2021 15;8:644957. Epub 2021 Apr 15.

Center for Proteomics and Metabolomics, State Key Laboratory of Biocontrol, Guangdong Key Laboratory of Pharmaceutical Functional Genes, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.

Development of immunity-based strategy to manage bacterial infection is urgently needed in aquaculture due to the widespread of antibiotic-resistant bacteria. Phagocytosis serves as the first line defense in innate immunity that engulfs bacteria and restricts their proliferations and invasions. However, the mechanism underlying the regulation of phagocytosis is not fully elucidated and the way to boost phagocytosis is not yet explored. Read More

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Hepatopancreatic transcriptome analysis and humoral immune factor assays in red claw crayfish (Cherax quadricarinatus) provide insight into innate immunomodulation under Vibrio parahaemolyticus infection.

Ecotoxicol Environ Saf 2021 Jul 27;217:112266. Epub 2021 Apr 27.

Aquaculture Research Lab, College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Taian 271018, China. Electronic address:

Red claw crayfish (Cherax quadricarinatus) is an economically and nutritionally important specie. We aimed to assess the immunostimulatory response to C. quadricarinatus infection with Vibrio parahaemolyticus. Read More

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The past and present of pandemic management: health diplomacy, international epidemiological surveillance, and COVID-19.

Flavio D'Abramo

Hist Philos Life Sci 2021 Apr 30;43(2):64. Epub 2021 Apr 30.

Max Planck Institute for the History of Science, Berlin, Germany.

The establishment of international sanitary institutions, which took place in the context of rivalry among the great European powers and their colonial expansion in Asia, allowed for the development of administrative systems of international epidemiological surveillance as a response to the cholera epidemics at the end of the nineteenth century. In this note, I reflect on how a historical analysis of the inception of international epidemiological surveillance and pandemic management helps us to understand what is happening in the COVID-19 pandemic today. Read More

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Etiological, epidemiological, and clinical features of acute diarrhea in China.

Nat Commun 2021 04 29;12(1):2464. Epub 2021 Apr 29.

The Institute for Disease Prevention and Control of PLA, Beijing, China.

National-based prospective surveillance of all-age patients with acute diarrhea was conducted in China between 2009‒2018. Here we report the etiological, epidemiological, and clinical features of the 152,792 eligible patients enrolled in this analysis. Rotavirus A and norovirus are the two leading viral pathogens detected in the patients, followed by adenovirus and astrovirus. Read More

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The Implication of Bacteria in the Winter Mortalities of the Critically Endangered .

Microorganisms 2021 Apr 26;9(5). Epub 2021 Apr 26.

Laboratory of Animal Physiology, Department of Zoology, Faculty of Science, School of Biology, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.

populations, constituting the largest bivalve mollusk endemic to the Mediterranean, is characterized as critically endangered, threatened by extinction. Among the various factors proposed as etiological agents are the and sp. parasites. Read More

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A Lymphoid Organ Specific Anti-Lipopolysaccharide Factor from Exhibits Strong Antimicrobial Activities.

Mar Drugs 2021 Apr 28;19(5). Epub 2021 Apr 28.

Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China.

Different shrimp species are known to possess apparent distinct resistance to different pathogens in aquaculture. However, the molecular mechanism underlying this finding still remains unknown. One kind of important antimicrobial peptides, anti-lipopolysaccharide factors (ALF), exhibit broad-spectrum antimicrobial activities. Read More

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Effect of Seawater Temperature Increase on the Occurrence of Coastal Cases: Korean National Surveillance Data from 2003 to 2016.

Int J Environ Res Public Health 2021 04 22;18(9). Epub 2021 Apr 22.

Department of Public Health, Korea University Graduate School, Seoul 02841, Korea.

The purpose of this study was to assess the association between seawater temperature and cases in coastal regions of Korea. All cases in coastal regions notified to the Korea Disease Control and Prevention Agency between 2003 and 2016 were included in this work. Data for seawater temperature on the south, west, and east coast during the study period were provided by the Korea Oceanographic Data Center of the National Institute of Fisheries Science. Read More

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Vaccine Efficacy of a Newly Developed Feed-Based Whole-Cell Polyvalent Vaccine against Vibriosis, Streptococcosis and Motile Aeromonad Septicemia in Asian Seabass, .

Vaccines (Basel) 2021 Apr 10;9(4). Epub 2021 Apr 10.

Aquatic Animal Health and Therapeutics Laboratory, Institute of Bioscience, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.

Multiple infections of several bacterial species are often observed under natural farm conditions. The infections would cause a much more significant loss compared to a single infectious agent. Vaccination is an essential strategy to prevent diseases in aquaculture, and oral vaccination has been proposed as a promising technique since it requires no handling of the fish and is easy to perform. Read More

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Bacterial RTX toxins and host immunity.

Curr Opin Infect Dis 2021 Jun;34(3):187-196

Laboratory of Molecular Biology of Bacterial Pathogens, Institute of Microbiology of the Czech Academy of Sciences, Vídeňská 1083, Prague, Czech Republic.

Purpose Of Review: RTX toxin action often defines the outcome of bacterial infections. Here, we discuss the progress in understanding the impacts of RTX toxin activities on host immunity.

Recent Findings: Bordetella pertussis CyaA activity paralyzes sentinel phagocytic cells by elevating cellular cAMP levels and blocks differentiation of infiltrating monocytes into bactericidal macrophages, promoting also de-differentiation of resident alveolar macrophages into monocyte-like cells. Read More

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