568 results match your criteria Vestibuloocular Reflex Testing


Video-head impulse test results in patients with Menière's disease related to duration and stage of disease.

J Vestib Res 2019 Mar 7. Epub 2019 Mar 7.

Apeldoorn Dizziness Centre, Gelre Hospital, Apeldoorn, The Netherlands.

Background: The video-head impulse test employs the vestibulo-ocular reflex (VOR) to assess vestibular function. To this day, no consensus has been reached among scientists in terms of whether or not vHIT results change in MD patients as the disease progresses.

Objective: To assess whether the vHIT is more often abnormal in later stages of MD compared to earlier stages. Read More

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http://dx.doi.org/10.3233/VES-190654DOI Listing

[Functional vestibulo-ocular reflex test].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2019 Mar;33(3):213-215;219

In recent years, the diagnosis and treatment of vertigo and balance disorders have become a hot topic of multidisciplinary attention. The evaluation method of vestibular function has also been improved, providing important evidence for the diagnosis and differential diagnosis of vertigo related diseases. Vestibular rehabilitation is one of the important methods for the treatment of vertigo diseases. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2019.03.007DOI Listing

Clinical Validity of Quantified Visually Enhanced Vestibulo-ocular Reflex Test to Detect Horizontal Semicircular Canal Hypofunction.

Otol Neurotol 2019 Mar;40(3):365-371

Neurolotlogy Unit, ENT Department.

Objective: To investigate the clinical validity of the mathematical measured VVOR test results to detect horizontal semicircular canal hypofunction.

Study Design: Prospective, nonrandomized, observational study.

Setting: Tertiary referral center, hospital. Read More

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http://dx.doi.org/10.1097/MAO.0000000000002090DOI Listing

[Cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS): a case report].

Rinsho Shinkeigaku 2019 Jan 29;59(1):27-32. Epub 2018 Dec 29.

Department of Neurology, National Hospital Organization Minamikyushu National Hospital.

Cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS) is a rare form of multisystem ataxia defined by a triad of cerebellar impairment, bilateral vestibular hypofunction, and somatosensory deficit. Here we present a patient with CANVAS. A 76-year-old woman whose parents were cousins had noted slowly worsening gait imbalance since age 67. Read More

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http://dx.doi.org/10.5692/clinicalneurol.cn-001209DOI Listing
January 2019
1 Read

Surgery-free video-oculography in mouse models: enabling quantitative and short-interval longitudinal assessment of vestibular function.

Neurosci Lett 2019 Mar 28;696:212-218. Epub 2018 Dec 28.

Department of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, Guangdong 518055, China. Electronic address:

Vestibulo-ocular reflex (VOR) responding to acceleration stimuli is originated from the vestibular apparatuses and thus widely used as an in vivo indicator of the vestibular function. We have developed a vestibular function testing (VFT) system that allows to evaluate VOR response with improved efficiency. The previously required surgical procedure has been avoided by using a newly designed animal-immobility setup. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03043940183088
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http://dx.doi.org/10.1016/j.neulet.2018.12.036DOI Listing
March 2019
2 Reads
2.055 Impact Factor

The Gaze Stabilization Test Following Concussion.

J Am Acad Audiol 2018 Nov 29. Epub 2018 Nov 29.

Department of Physical Therapy, University of Pittsburgh, Pittsburgh, PA.

Background: Concussion can cause vestibular dysfunction and oculomotor abnormalities which can lead to dizziness and protracted recovery time. There are few clinically useful, functional measures of the vestibulo-ocular reflex (VOR) post-concussion.

Purpose: The purpose of this study was to examine the gaze stabilization test (GST) in those referred for vestibular physical therapy following concussion, to determine the association between GST and other measures of recovery following concussion, and to examine the effect of demographic variables on GST performance. Read More

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https://www.ingentaconnect.com/content/10.3766/jaaa.18015
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http://dx.doi.org/10.3766/jaaa.18015DOI Listing
November 2018
4 Reads

Assessment of vision in concussion.

Curr Opin Neurol 2019 Feb;32(1):68-74

Department of Neurology.

Purpose Of Review: To review emerging vision-based assessments in the evaluation of concussion.

Recent Findings: Involvement of the visual pathways is common following concussion, the mildest form of traumatic brain injury. The visual system contains widely distributed networks that are prone to neurophysiologic changes after a concussion, resulting in visual symptoms and ocular motor dysfunction. Read More

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http://dx.doi.org/10.1097/WCO.0000000000000654DOI Listing
February 2019
12 Reads

Superficial Siderosis of the Central Nervous System: Neurotological Findings Related to Magnetic Resonance Imaging.

Otol Neurotol 2019 Jan;40(1):31-37

Department of Otorhinolaryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, University of Bern, Switzerland.

Objective: To compare the neurotological results of five patients suffering from progressive hearing loss and ataxia due to superficial siderosis (SS) with the magnetic resonance imaging (MRI) findings.

Study Design: Retrospective case review.

Setting: Primary and hospital care center. Read More

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http://Insights.ovid.com/crossref?an=00129492-900000000-9657
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http://dx.doi.org/10.1097/MAO.0000000000002071DOI Listing
January 2019
12 Reads

Vertical head impulse and caloric are complementary but react opposite to Meniere's disease hydrops.

Laryngoscope 2018 Dec 4. Epub 2018 Dec 4.

Department of Otolaryngology, University of Tokushima School of Medicine, Tokushima, Japan.

Objectives/hypothesis: Meniere's disease (MD) patients can show normal head impulses despite poor caloric test results. This study aimed to investigate the discrepancy in the vestibulo-ocular reflex (VOR) in MD patients and whether endolymphatic hydrops (EH) influence the VOR.

Study Design: Prospective, cross-sectional observational study. Read More

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http://dx.doi.org/10.1002/lary.27580DOI Listing
December 2018
19 Reads

Functional Head Impulse Testing Might Be Useful for Assessing Vestibular Compensation After Unilateral Vestibular Loss.

Front Neurol 2018 19;9:979. Epub 2018 Nov 19.

Department of Clinical Sciences Lund, Faculty of Medicine, Skåne University Hospital, Lund University, Lund, Sweden.

Loss of the vestibulo-ocular reflex (VOR) affects visual acuity during head movements. Previous studies have shown that compensatory eye-saccades improve visual acuity and that the timing of the saccade is important. Most of the tests involved in testing VOR are made with passive head movement, that do not necessarily reflect the activities of daily living and thus not being proportionate to symptoms and distresses of the patients. Read More

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http://dx.doi.org/10.3389/fneur.2018.00979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252383PMC
November 2018
11 Reads

Effect of Intensity Level and Speech Stimulus Type on the Vestibulo-Ocular Reflex.

J Am Acad Audiol 2018 Nov 15. Epub 2018 Nov 15.

Department of Audiology and Speech Pathology, University of Tennessee Health Science Center, Knoxville, TN.

Background: Accurate vestibulo-ocular reflex (VOR) measurement requires control of extravestibular suppressive factors such as visual fixation. Although visual fixation is the dominant suppressor and has been extensively studied, the mechanisms underlying suppression from nonvisual factors of attention and auditory stimulation are less clear. It has been postulated that the nonvisual suppression of the VOR is the result of one of two mechanisms: (1) activation of auditory reception areas excites efferent pathways to the vestibular nuclei, thus inhibiting the VOR or (2) cortical modulation of the VOR results from directed attention, which implies a nonmodality-specific process. Read More

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http://dx.doi.org/10.3766/jaaa.18016DOI Listing
November 2018
12 Reads

Enhanced Vestibulo-Ocular Reflex Responses on vHIT. Is It a Casual Finding or a Sign of Vestibular Dysfunction?

Front Neurol 2018 15;9:866. Epub 2018 Oct 15.

Vestibular Research Laboratory, School of Psychology, The University of Sydney, Sydney, NSW, Australia.

In current clinical practice, when in response to vHIT testing the observed slow-phase eye-velocity responses are significantly higher than head velocity, the most probable cause is considered to be an inadequate collection method or a recording artifact. We present two cases with clinical diagnoses of Menière's Disease: for both cases, enhanced eye velocity responses were measured with a rigorous vHIT testing protocol. In the first case we measured these enhanced responses on each test performed during a 5 year time series; in the second case multiple measurements were obtained from a patient after the radiologic diagnosis of vestibulo-cochlear hydrops. Read More

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https://www.frontiersin.org/article/10.3389/fneur.2018.00866
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http://dx.doi.org/10.3389/fneur.2018.00866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196253PMC
October 2018
15 Reads

Oculomotor Function in Individuals With Rett Syndrome.

Pediatr Neurol 2018 Nov 30;88:48-58. Epub 2018 Aug 30.

Rett Expertise Centre Netherlands - GKC, Maastricht University Medical Center, Maastricht, The Netherlands.

Background: Individuals with Rett syndrome (RTT) are notoriously reliant on the use of eye gaze as a primary means of communication. Underlying an ability to communicate successfully via eye gaze is a complex matrix of requirements, with an intact oculomotor system being just one element. To date, the underlying neural and motor pathways associated with eye gaze are relatively under-researched in RTT. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08878994183070
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http://dx.doi.org/10.1016/j.pediatrneurol.2018.08.022DOI Listing
November 2018
16 Reads

An Assay for Systematically Quantifying the Vestibulo-Ocular Reflex to Assess Vestibular Function in Zebrafish Larvae.

Front Cell Neurosci 2018 21;12:257. Epub 2018 Aug 21.

Department of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, China.

Zebrafish () larvae are widely used to study otic functions because they possess all five typical vertebrate senses including hearing and balance. Powerful genetic tools and the transparent body of the embryo and larva also make zebrafish a unique vertebrate model to study otic development. Due to its small larval size and moisture requirement during experiments, accurately acquiring the vestibulo-ocular reflex (VOR) of zebrafish larva is challenging. Read More

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http://dx.doi.org/10.3389/fncel.2018.00257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113563PMC
August 2018
4 Reads

Usability of the Video Head Impulse Test: Lessons From the Population-Based Prospective KORA Study.

Front Neurol 2018 17;9:659. Epub 2018 Aug 17.

German Center for Vertigo and Balance Disorders, University Hospital Munich, Ludwig-Maximilians Universität München, Munich, Germany.

The video head impulse test (vHIT) has become a common examination in the work-up for dizziness and vertigo. However, recent studies suggest a number of pitfalls, which seem to reduce vHIT usability. Within the framework of a population-based prospective study with naïve examiners, we investigated the relevance of previously described technical mistakes in vHIT testing, and the effect of experience and training. Read More

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http://dx.doi.org/10.3389/fneur.2018.00659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107793PMC
August 2018
2 Reads

Dissociation between caloric and head impulse testing in patients with congenital abnormalities of the semicircular canals.

Authors:
B Shaw R S Raghavan

J Laryngol Otol 2018 Oct 8;132(10):932-935. Epub 2018 Aug 8.

Audiovestibular Medicine,Royal Surrey County Hospital,Guildford,UK.

Background: Dissociation between caloric and head impulse test results in patients with vestibular disorders has been well documented since the introduction of video head impulse testing. Prior to the introduction of video head impulse testing, vestibular diagnostic services relied mainly on caloric testing, and it is now known that the caloric testing shows more positive results than video head impulse testing. A dissipation model was proposed to explain this dissociation. Read More

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http://dx.doi.org/10.1017/S0022215118001317DOI Listing
October 2018
13 Reads

The video head impulse test: a right-left imbalance.

J Neurol 2018 Oct 6;265(Suppl 1):40-43. Epub 2018 Aug 6.

Department of Neurology and German Center for Vertigo and Balance Disorders, Campus Grosshadern, Ludwig Maximilians University, Munich, Marchioninistr. 15, 81377, Munich, Germany.

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http://dx.doi.org/10.1007/s00415-018-8986-5DOI Listing
October 2018
20 Reads

Head-Movement-Emphasized Rehabilitation in Bilateral Vestibulopathy.

Front Neurol 2018 17;9:562. Epub 2018 Jul 17.

German Center for Vertigo and Balance Disorders, Ludwig Maximilians University, Munich, Germany.

Although there is evidence that vestibular rehabilitation is useful for treating chronic bilateral vestibular hypofunction (BVH), the mechanisms for improvement, and the reasons why only some patients improve are still unclear. Clinical rehabilitation results and evidence fromeye-head control in vestibular deficiency suggest that headmovement is a crucial element of vestibular rehabilitation. In this study, we assess the effects of a specifically designed head-movement-based rehabilitation program on dynamic vision, and explore underlying mechanisms. Read More

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http://dx.doi.org/10.3389/fneur.2018.00562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057116PMC
July 2018
1 Read

Bilateral Vestibulopathy: Vestibular Function, Dynamic Visual Acuity and Functional Impact.

Front Neurol 2018 10;9:555. Epub 2018 Jul 10.

INSERM U1028, CNRS UMR5292, Lyon Neuroscience Research Center, Equipe IMPACT, Lyon, France.

Patients suffering from bilateral vestibular hypofunction (BVH) often experience ataxia as well as visual instability. Even though progress has been made in vestibular testing, insights regarding vestibular deficit in BVH remain incomplete since no method allows evaluation of frequency ranges of vestibular sensors in a continuous way. The aim of our study was to give a detailed description of the level of vestibular deficit in different ranges of vestibular stimulation and an exhaustive evaluation of the functional impact including dynamic visual acuity (DVA) in a cohort of BVH patients in different etiologies. Read More

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http://dx.doi.org/10.3389/fneur.2018.00555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048872PMC
July 2018
6 Reads

Long-term effects of vestibular rehabilitation and head-mounted gaming task procedure in unilateral vestibular hypofunction: a 12-month follow-up of a randomized controlled trial.

Clin Rehabil 2019 Jan 16;33(1):24-33. Epub 2018 Jul 16.

1 Department of Clinical Sciences and Translational Medicine, University of Rome "Tor Vergata," Rome, Italy.

Objective:: To investigate the long-term effects of adding virtual reality-based home exercises to vestibular rehabilitation in people with unilateral vestibular hypofunction.

Design:: Follow-up otoneurological examination in two randomized groups following a previous one-month trial.

Setting:: Tertiary rehabilitation center. Read More

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http://dx.doi.org/10.1177/0269215518788598DOI Listing
January 2019
3 Reads

The Early Postoperative Effects of Cochlear Implantation on Horizontal Semicircular Canal Function.

Otol Neurotol 2018 Aug;39(7):e524-e531

Department of Surgery (Otolaryngology) University of Melbourne.

Objectives: To use video head impulse testing to examine the effect of cochlear implantation (CI) on horizontal SCC vestibulo-ocular reflex (VOR) gain early after surgery, and to relate outcomes to subjective imbalance.

Study Design: Prospective cohort study.

Setting: Academic tertiary referral center. Read More

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http://dx.doi.org/10.1097/MAO.0000000000001840DOI Listing

Association of the Video Head Impulse Test With Improvement of Dynamic Balance and Fall Risk in Patients With Dizziness.

JAMA Otolaryngol Head Neck Surg 2018 Aug;144(8):696-703

Laboratory of Vestibular NeuroAdaptation, Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Importance: It is important to know whether recovery of the vestibuloocular reflex (VOR) as measured by the video head impulse test (vHIT) is associated with the recovery of dynamic balance. It is also critical to know how much change in VOR gain is clinically relevant for establishing the recovery of dynamic balance.

Objectives: To investigate the association between improved VOR gain as measured by the vHIT and improved dynamic balance (reduced fall risk) as measured by the dynamic gait index (DGI) and to calculate the minimal clinically important difference of VOR gain. Read More

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http://dx.doi.org/10.1001/jamaoto.2018.0650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143005PMC
August 2018
12 Reads

The Reliance on Vestibular Information During Standing Balance Control Decreases With Severity of Vestibular Dysfunction.

Front Neurol 2018 4;9:371. Epub 2018 Jun 4.

Department of Neurology, University Medical Center Freiburg, Freiburg, Germany.

The vestibular system is involved in gaze stabilization and standing balance control. However, it is unclear whether vestibular dysfunction affects both processes to a similar extent. Therefore, the objective of this study was to determine how the reliance on vestibular information during standing balance control is related to gaze stabilization deficits in patients with vestibular dysfunction. Read More

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http://dx.doi.org/10.3389/fneur.2018.00371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994722PMC
June 2018
8 Reads

Bilateral Vestibular Weakness.

Front Neurol 2018 31;9:344. Epub 2018 May 31.

Department of Neurology, Dr. Cesar Milstein Hospital, Buenos Aires, Argentina.

Bilateral vestibular weakness (BVW) is a rare cause of imbalance. Patients with BVW complain of oscillopsia. In approximately half of the patients with BVW, the cause remains undetermined; in the remainder, the most common etiology by far is gentamicin ototoxicity, followed by much rarer entities such as autoimmune inner ear disease, meningitis, bilateral Ménière's disease, bilateral vestibular neuritis, and bilateral vestibular schwannomas. Read More

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http://dx.doi.org/10.3389/fneur.2018.00344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990606PMC
May 2018
10 Reads

Neuro-ophthalmologic assessment and investigations in children and adults with cerebellar diseases.

Handb Clin Neurol 2018 ;154:305-327

Section of Pediatric Neurology, Department of Pediatrics and Child Health, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada. Electronic address:

In this chapter, we present the bedside assessment and laboratory tests that are available for the neuro-ophthalmologic evaluation of children and adults with cerebellar diseases. In the evaluation of a patient with cerebellar dysfunction, recognizing the pattern of ocular motor and / or vestibular impairment is often a key step to the correct diagnosis. The cerebellum is very important in processing a wide range of different eye movements, including angular vestibulo-ocular reflexes, otolith-ocular reflexes, fixation and gaze holding, smooth pursuit eye movements, saccadic eye movements, optokinetic response, ocular alignment, and vergence. Read More

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http://dx.doi.org/10.1016/B978-0-444-63956-1.00019-9DOI Listing
September 2018
5 Reads

Vestibular Function and Hippocampal Volume in the Baltimore Longitudinal Study of Aging (BLSA).

Otol Neurotol 2018 Jul;39(6):765-771

Department of Otolaryngology-Head and Neck Surgery.

Objective: This study evaluated whether reduced vestibular function in aging adults is associated with lower hippocampal volume.

Study Design: Cross-sectional study.

Setting: Baltimore Longitudinal Study of Aging, a long-running longitudinal cohort study of healthy aging. Read More

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http://Insights.ovid.com/crossref?an=00129492-201807000-0002
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http://dx.doi.org/10.1097/MAO.0000000000001838DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999049PMC
July 2018
2 Reads

Acute Bilateral Superior Branch Vestibular Neuropathy.

Front Neurol 2018 17;9:353. Epub 2018 May 17.

Johns Hopkins University, Otolaryngology, Baltimore, MD, United States.

The rapid onset of a bilateral vestibular hypofunction (BVH) is often attributed to vestibular ototoxicity. However, without any prior exposure to ototoxins, the idiopathic form of BVH is most common. Although sequential bilateral vestibular neuritis (VN) is described as a cause of BVH, clinical evidence for simultaneous and acute onset bilateral VN is unknown. Read More

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http://dx.doi.org/10.3389/fneur.2018.00353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966533PMC
May 2018
9 Reads

Characteristics of vestibular corrective saccades in patients with slow visual saccades, vestibular disorders and controls: A descriptive analysis.

PLoS One 2018 30;13(5):e0197079. Epub 2018 May 30.

Northwestern University, Chicago, Illinois, United States of America.

Objective: Our aim was to determine whether overt catch up saccades (OS) provoked by vestibular stimuli, as observed in the video head impulse test (vHIT), have comparable metrics as visually triggered horizontal saccades (VS), indicating a common saccadic brainstem generator.

Methods: Three groups of patients were studied: patients with neurological disorders causing slow saccades (group 1, n = 12), patients with peripheral vestibular lesions (group 2, n = 43), and normal controls (group 3, = 24). All patients underwent vHIT and Videooculographic testing. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0197079PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976173PMC
August 2018
4 Reads

[Etiology analysis and vestibular assessment of bilateral vestibular vestibulopathy].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Mar;32(5):379-382

Department of Otolaryngology Head Neck Surgery, Xijing Hospital, Medical University of the Air Force, Xi'an, 710032, China.

To define clinical and laboratory characteristics of bilateral vestibulopathy(BVP) and to propose diagnostic criteria of this disorder based on clinical and laboratory vestibular function test findings.Forty-two case series with a clinical suspicion of BVP were retrospectively analyzed, in an attempt to determine etiology. Presenting auditory-vestibular symptoms, bedside dynamic visual acuity tests and laboratory test were reviewed, including bithermal caloric test, rotatory chair tests, video head impulse test (vHIT), vestibular-evoked myogenic potentials (VEMP). Read More

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http://www.cnki.net/kcms/doi/10.13201/j.issn.1001-1781.2018.
Publisher Site
http://dx.doi.org/10.13201/j.issn.1001-1781.2018.05.015DOI Listing
March 2018
5 Reads

Video Head Impulse Testing in a Pediatric Population: Normative Findings.

J Am Acad Audiol 2018 May;29(5):417-426

Department of Audiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

Background: The video head impulse test (vHIT) is a new tool being used in vestibular clinics to assess the function of all six semicircular canals (SCCs) by measuring the gain of the vestibulo-ocular reflex (VOR) in response to rapid head turns. Whereas vHIT has been validated in adults for all SCCs, there are few studies describing the normal response in children, particularly for stimulation of the vertical canals.

Purpose: The purpose of this study was to characterize the normal vHIT response for all six SCCs in children aged 4-12 years. Read More

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http://dx.doi.org/10.3766/jaaa.17076DOI Listing
May 2018
4 Reads

Cerebellar ataxia, neuropathy, vestibular areflexia syndrome (CANVAS) with chronic cough and preserved muscle stretch reflexes: evidence for selective sparing of afferent Ia fibres.

J Neurol 2018 Jun 25;265(6):1454-1462. Epub 2018 Apr 25.

Service of Neurology, University Hospital "Marqués de Valdecilla (IDIVAL)", University of Cantabria, and "Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED)", Santander, Spain.

The aim of this study was to describe five patients with cerebellar ataxia, neuropathy and vestibular areflexia syndrome (CANVAS) with chronic cough and preserved limb muscle stretch reflexes. All five patients were in the seventh decade of age, their gait imbalance having been initiated in the fifth decade. In four patients cough antedated gait imbalance between 15 and 29 years; cough was spasmodic and triggered by variable factors. Read More

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http://link.springer.com/10.1007/s00415-018-8872-1
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http://dx.doi.org/10.1007/s00415-018-8872-1DOI Listing
June 2018
24 Reads

Hierarchical Cluster Analysis of Semicircular Canal and Otolith Deficits in Bilateral Vestibulopathy.

Front Neurol 2018 10;9:244. Epub 2018 Apr 10.

Department of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

Background: Gait imbalance and oscillopsia are frequent complaints of bilateral vestibular loss (BLV). Video-head-impulse testing (vHIT) of all six semicircular canals (SCCs) has demonstrated varying involvement of the different canals. Sparing of anterior-canal function has been linked to aminoglycoside-related vestibulopathy and Menière's disease. Read More

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http://dx.doi.org/10.3389/fneur.2018.00244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902493PMC
April 2018
6 Reads

Consensus Paper: Neurophysiological Assessments of Ataxias in Daily Practice.

Cerebellum 2018 Oct;17(5):628-653

Department of Neurology, Essen University Hospital, University of Duisburg-Essen, Essen, Germany.

The purpose of this consensus paper is to review electrophysiological abnormalities and to provide a guideline of neurophysiological assessments in cerebellar ataxias. All authors agree that standard electrophysiological methods should be systematically applied in all cases of ataxia to reveal accompanying peripheral neuropathy, the involvement of the dorsal columns, pyramidal tracts and the brainstem. Electroencephalography should also be considered, although findings are frequently non-specific. Read More

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http://dx.doi.org/10.1007/s12311-018-0937-2DOI Listing
October 2018
5 Reads

Range of Peak Head Velocity in Video Head Impulse Testing for Pediatric Patients.

Otol Neurotol 2018 Jun;39(5):e357-e361

Department of Otolaryngology and Communication Enhancement, Boston Children's Hospital, Waltham.

Objective: To examine peak head velocity in video head impulse testing of pediatric patients and its effect on vestibulo-ocular reflex (VOR) gain.

Study Design: Retrospective case review.

Setting: Tertiary referral center. Read More

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http://dx.doi.org/10.1097/MAO.0000000000001793DOI Listing
June 2018
4 Reads

Intratympanic Gentamicin for Intractable Ménière's Disease - A Review and Analysis of Audiovestibular Impact.

Authors:
Sertaç Yetişer

Int Arch Otorhinolaryngol 2018 Apr 17;22(2):190-194. Epub 2017 Jul 17.

Department of Otorhinolaryngology, Anadolu Saglik Merkezi, Gebze, Kocaeli, Turkey.

 Intratympanic gentamicin regulates the symptoms in most patients with incapacitating Ménière's disease. The treatment protocols have changed over the years from medical labyrinthectomy to preservation of vestibular function.  This study aims to review the audiovestibular response related to the effect of the drug in controlling vertigo. Read More

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http://dx.doi.org/10.1055/s-0037-1604064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882374PMC
April 2018
1 Read

The Video Head Impulse Test and the Influence of Daily Use of Spectacles to Correct a Refractive Error.

Front Neurol 2018 7;9:125. Epub 2018 Mar 7.

Division of Balance Disorders, Department of Otorhinolaryngology and Head and Neck Surgery, Faculty of Health Medicine and Life Sciences, School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, Netherlands.

Objective: To determine the influence of daily use of spectacles to correct a refractive error, on the vestibulo-ocular reflex (VOR) gain measured with the video head impulse test (vHIT).

Study Design: This prospective study enrolled subjects between 18 and 80 years old with and without a refractive error. Subjects were classified into three groups: (1) contact lenses, (2) spectacles, and (3) control group without visual impairment. Read More

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http://dx.doi.org/10.3389/fneur.2018.00125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863505PMC

Vestibular Dysfunction in Wernicke's Encephalopathy: Predominant Impairment of the Horizontal Semicircular Canals.

Front Neurol 2018 12;9:141. Epub 2018 Mar 12.

Department of Neurology, University Hospital Zurich, Zurich, Switzerland.

Background: Wernicke's encephalopathy (WE), a metabolic disorder due to thiamine deficiency, manifests with various neurological symptoms and signs. It has been known as a cause of vestibular dysfunction. Preliminary reports have proposed predominant involvement of the horizontal semicircular canals (HSCs). Read More

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http://dx.doi.org/10.3389/fneur.2018.00141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857915PMC
March 2018
9 Reads

The Dizziness Handicap Inventory does not correlate with vestibular function tests: a prospective study.

J Neurol 2018 May 20;265(5):1210-1218. Epub 2018 Mar 20.

Department of Neurology and German Center for Vertigo and Balance Disorders (DSGZ), Ludwig Maximilian University, Munich, Germany.

The Dizziness Handicap Inventory (DHI) is believed to quantitate the handicap related to the presence or severity of underlying vestibular dysfunction. However, patients with chronic vestibular diseases may manifest various degrees of behavioural and physiological adaptation resulting in variances of the DHI. Our primary study objective is to evaluate the correlation between the DHI and measurable vestibular parameters. Read More

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http://link.springer.com/10.1007/s00415-018-8834-7
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http://dx.doi.org/10.1007/s00415-018-8834-7DOI Listing
May 2018
8 Reads

Impact of NMDA Receptor Overexpression on Cerebellar Purkinje Cell Activity and Motor Learning.

eNeuro 2018 Jan-Feb;5(1). Epub 2018 Feb 12.

Department of Neuroscience, Erasmus Medical Centre, Rotterdam, The Netherlands.

In many brain regions involved in learning NMDA receptors (NMDARs) act as coincidence detectors of pre- and postsynaptic activity, mediating Hebbian plasticity. Intriguingly, the parallel fiber (PF) to Purkinje cell (PC) input in the cerebellar cortex, which is critical for procedural learning, shows virtually no postsynaptic NMDARs. Why is this? Here, we address this question by generating and testing independent transgenic lines that overexpress NMDAR containing the type 2B subunit (NR2B) specifically in PCs. Read More

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http://dx.doi.org/10.1523/ENEURO.0270-17.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815660PMC
January 2019
5 Reads

Neurological Manifestations Among US Government Personnel Reporting Directional Audible and Sensory Phenomena in Havana, Cuba.

JAMA 2018 03;319(11):1125-1133

Center for Brain Injury and Repair, University of Pennsylvania, Philadelphia.

Importance: From late 2016 through August 2017, US government personnel serving on diplomatic assignment in Havana, Cuba, reported neurological symptoms associated with exposure to auditory and sensory phenomena.

Objective: To describe the neurological manifestations that followed exposure to an unknown energy source associated with auditory and sensory phenomena.

Design, Setting, And Participants: Preliminary results from a retrospective case series of US government personnel in Havana, Cuba. Read More

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http://dx.doi.org/10.1001/jama.2018.1742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885885PMC
March 2018
10 Reads
1 Citation
35.290 Impact Factor

Vestibulo-ocular reflex gain values in the suppression head impulse test of healthy subjects.

Laryngoscope 2018 10 15;128(10):2383-2389. Epub 2018 Feb 15.

Department of Otorhinolaryngology, Clínica Universidad de Navarra, Madrid, Spain.

Objective: To assess whether there are differences in vestibulo-ocular reflex (VOR) gain for suppression head impulse (SHIMP) and head impulse (HIMP) video head impulse test paradigms, and if so, what are their causes.

Methods: Prospective multicenter observational double-blind nonrandomized clinical study was performed by collecting 80 healthy subjects from four reference hospitals. SHIMP data was postprocessed to eliminate impulses in which early SHIMP saccades were detected. Read More

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http://dx.doi.org/10.1002/lary.27107DOI Listing
October 2018
13 Reads

Vergence increases the gain of the human angular vestibulo-ocular reflex during peripheral hyposensitivity elicited by cold thermal irrigation.

J Vestib Res 2018 ;27(5-6):265-270

Department of Otolaryngology, Karl Landsteiner University Hospital Krems, Krems an der Donau, Austria.

Background: When viewing a far target, the gain of the horizontal vestibulo-ocular reflex (VOR) is around 1.0, but when viewing a near target there is an increased response. It has been shown that while this convergence-mediated modulation is unaffected by canal plugging and clinically practical transmastoid galvanic stimulation, it is eliminated by a partial peripheral gentamicin lesion. Read More

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http://www.medra.org/servlet/aliasResolver?alias=iospress&am
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http://dx.doi.org/10.3233/VES-170629DOI Listing
September 2018
4 Reads

Location and phase effects for ocular and cervical vestibular-evoked myogenic potentials evoked by bone-conducted stimuli at midline skull sites.

J Neurophysiol 2018 03 13;119(3):1045-1056. Epub 2017 Dec 13.

Prince of Wales Clinical School and Neuroscience Research Australia, University of New South Wales, Randwick, Sydney, New South Wales , Australia.

Our object was to investigate the effect of location and phase on the properties of oVEMPs and cVEMPs evoked by two bone conducted (BC) stimuli, 500 Hz and an impulsive stimulus for midline skull sites from Nz to Iz, in normal volunteers. Compressive and rarefactive onset phases were used and the induced linear and rotational accelerations measured. We confirmed our previous finding of marked changes in the polarity of oVEMPs with location. Read More

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http://www.physiology.org/doi/10.1152/jn.00695.2017
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http://dx.doi.org/10.1152/jn.00695.2017DOI Listing
March 2018
3 Reads

[Video-Head impulse test with little diagnostic impact in vertigo-patients].

Laryngorhinootologie 2018 03 19;97(3):181-188. Epub 2017 Dec 19.

Objective: Video-head impulse test (V-HIT) is more and more becoming a routine test in patients with vertigo, contributing information about the vestibulo-ocular reflex (VOR). According to Ewald's second law, the unilateral pathological test points to this side's peripheral organ as being diseased. The value in clinical routine is still unclear. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-122743
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http://dx.doi.org/10.1055/s-0043-122743DOI Listing
March 2018
6 Reads

Bilateral vestibulopathy: Diagnostic criteria Consensus document of the Classification Committee of the Bárány Society.

J Vestib Res 2017 ;27(4):177-189

Department of Otolaryngology, Maastricht, The Netherlands/Department of Medical Physics, Tomsk Research State University, Russian Federation.

This paper describes the diagnostic criteria for bilateral vestibulopathy (BVP) by the Classification Committee of the Bárány Society. The diagnosis of BVP is based on the patient history, bedside examination and laboratory evaluation. Bilateral vestibulopathy is a chronic vestibular syndrome which is characterized by unsteadiness when walking or standing, which worsen in darkness and/or on uneven ground, or during head motion. Read More

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http://www.medra.org/servlet/aliasResolver?alias=iospress&am
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http://dx.doi.org/10.3233/VES-170619DOI Listing
June 2018
16 Reads

Development of a new software and test setup for analyzing hVOR in very young children by vHIT.

J Vestib Res 2017 ;27(2-3):155-162

Section of Phoniatrics, Pedaudiology and Neurootology, Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Centre Mannheim, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.

Introduction: Earlier work revealed that vHIT examination is often difficult to perform on very young children. In particular, the calibration of the system can be difficult, as active cooperation of the patient is required. Additionally, the patient must be able to follow the examiner's instructions, which is challenging for very young children. Read More

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http://dx.doi.org/10.3233/VES-170611DOI Listing
June 2018
14 Reads

A low-cost video-oculography system for vestibular function testing.

Conf Proc IEEE Eng Med Biol Soc 2017 07;2017:4078-4081

In order to remain in focus during head movements, vestibular-ocular reflex causes eyes to move in the opposite direction to head movement. Disorders of vestibular system decrease vision, causing abnormal nystagmus and dizziness. To diagnose abnormal nystagmus, various studies have been reported including the use of rotating chair tests and videonystagmography. Read More

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http://dx.doi.org/10.1109/EMBC.2017.8037752DOI Listing
July 2017
3 Reads

Preferential Impairment of the Contralesional Posterior Semicircular Canal in Internuclear Ophthalmoplegia.

Front Neurol 2017 22;8:502. Epub 2017 Sep 22.

Department of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

Background: The vertical vestibulo-ocular reflex (VOR) may be impaired in internuclear ophthalmoplegia (INO) as the medial longitudinal fasciculus (MLF) conveys VOR-signals from the vertical semicircular canals. It has been proposed that signals from the contralesional posterior semicircular canal (PSC) are exclusively transmitted through the MLF, while for the contralesional anterior canal other pathways exist.

Objective: Here, we aimed to characterize dysfunction in individual canals in INO-patients using the video-head-impulse test (vHIT) and to test the hypothesis of dissociated vertical canal impairment in INO. Read More

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http://dx.doi.org/10.3389/fneur.2017.00502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614936PMC
September 2017
8 Reads

Video Head Impulse Tests with a Remote Camera System: Normative Values of Semicircular Canal Vestibulo-Ocular Reflex Gain in Infants and Children.

Front Neurol 2017 7;8:434. Epub 2017 Sep 7.

Center for Interdisciplinary Research in Biology (CIRB), College de France, CNRS, INSERM, PSL Research University, Paris, France.

The video head impulse test (VHIT) is widely used to identify semicircular canal function impairments in adults. But classical VHIT testing systems attach goggles tightly to the head, which is not tolerated by infants. Remote video detection of head and eye movements resolves this issue and, here, we report VHIT protocols and normative values for children. Read More

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http://journal.frontiersin.org/article/10.3389/fneur.2017.00
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http://dx.doi.org/10.3389/fneur.2017.00434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594068PMC
September 2017
7 Reads

RELATIONSHIPS AMONG COMMON VISION AND VESTIBULAR TESTS IN HEALTHY RECREATIONAL ATHLETES.

Int J Sports Phys Ther 2017 Aug;12(4):581-591

A.T. Still University, Mesa, AZ, USA.

Background: Disruption of the visual and vestibular systems is commonly observed following concussion. Researchers have explored the utility of screening tools to identify deficits in these systems in concussed patients, but it is unclear if these tests are measuring similar or distinct phenomena.

Purpose: To determine the relationships between common vestibular tests including the King-Devick (K-D) test, Sensory Organization Test (SOT), Head Shake-Sensory Organization Test (HS-SOT), and Dynamic Visual Acuity (DVA) test, when administered contiguously, to healthy recreational athletes aged 14 to 24 years. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534148PMC
August 2017
11 Reads