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Auris Nasus Larynx 2021 Apr 25. Epub 2021 Apr 25.

Department of Radiology, "Medikol" Policlinic Split, Split, Croatia.

This is a unique presentation of an acute vestibular syndrome (AVS) caused by vestibular neuronitis (VN) of a vestibular nerve (CNVIII) already affected by vestibular schwannoma (VS). A 48-year-old patient, formerly diagnosed with an intracanalicular VS, presented with AVS. The patient underwent clinical and neurotological examination including video Head Impulse Test and a 4-hour delayed-enhanced 3D-FLAIR MRI using intravenous gadolinium. Read More

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 Apr;35(4):289-292

Department of Otology，Qinhuangdao First Hospital，Qinhuangdao，066000，China.

To analyze results obtained from high frequency semicircular canal function test in patients with unilateral vestibular neuronitis in the acute phase, aiming to provide references for clinical vestibular rehabilitation. A total of 49 patients with unilateral vestibular neuronitis in the acute phase were enrolled in this study. They were subjected to video head impulse test（vHIT） and vestibular autorotation test（VAT）. Read More

Pan Afr Med J 2021 13;38:30. Epub 2021 Jan 13.

Department of Otolaryngology, Head and Neck Surgery, Cheikh Khalifa International University Hospital, Faculty of Medicine, Mohammed VI University of Health Sciences (UM6SS), Casablanca, Morocco.

SARS-CoV-2 is an infection due to a novel virus belonging to the coronavirus family. Since December 2019, first human cases of COVID-19 have been identified in Wuhan (China) and rapidly has been progressed to a global pandemic declared by the world health organization (WHO) on March 11 2020. The major complication of COVID-19, is pneumonia, but other presentations like cardiovascular and neurological complications have been reported. Read More

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 Mar;56(3):280-284

Department of Otorhinolaryngology Head and Neck Surgery, Tianjin First Central Hospital, Institute of Otolaryngology of Tianjin, Tianjin Key Laboratory of Auditory Speech and Balance Medicine, Key Clinical Discipline of Tianjin (Otolaryngology), Otorhinolaryngology Clinical Quality Control Centre of Tianjin, Tianjin 300192, China.

The aim of the study is to analyze the effects of vestibular spontaneous nystagmus(SN) on the smooth pursuit function of visual ocularmotor system. A total of 46 patients with acute unilateral peripheral vestibular syndrome with SN (26 cases of vestibular neuritis, 6 cases of Ramsay Hunt Syndrome (RHS) with vertigo, 14 cases of sudden deafness with vertigo) were included in this work. In the study group, the results of SPT and SN test with videonystagmography(VNG) were also reviewed. Read More

Infez Med 2021 Mar;29(1):117-122

Bay Area Hospital, Coos Bay, Oregon, USA.

Respiratory symptoms are the most common presentation of an acute COVID-19 infection, but thromboembolic phenomena, encephalopathy and other neurological symptoms have been reported. With these case series, we present multiple presentations of COVID-19 induced vestibular symptoms namely dizziness, vertigo and nystagmus. The patients reported in this case series are from different parts of the world, belong to different age groups and had manifested these symptoms in different periods of the pandemic. Read More

Neurologist 2021 Mar 4;26(2):36-40. Epub 2021 Mar 4.

Department of Neurology, Centro Hospitalar Universitário de Lisboa Central, Lisbon, Portugal.

Background: Acute vertigo (AV) is often a challenging condition. Because of its multiple causes, patients are frequently observed by neurologists and physicians from other areas of specialites, particularly Ear, Nose, and Throat (ENT). We aimed to assess the diagnostic accuracy of AV in patients observed by Neurology and other medical specialties. Read More

Zh Nevrol Psikhiatr Im S S Korsakova 2020 ;120(12):131-137

Pirogov Russian National Research Medical University, Moscow, Russia.

Chronic dizziness is defined as a complex of symptoms lasting months or years, including oscillopsia, nystagmus, and postural instability. Diagnostic search includes peripheral vestibulopathy - chronic unilateral vestibulopathy resulting from vestibular neuronitis, schwannoma of the 8th pair of cranial nerves, medical or surgical ablation of the labyrinth, and bilateral vestibulopathy; central vestibulopathy - syndromes accompanied by central vertical nystagmus, small vessel disease in patients with chronic cerebral ischemia; general somatic diseases, peripheral polyneuropathy, side-effects of medications as well as persistent postural-perceptual dizziness. Often, when collecting an anamnesis, it is not possible to identify specific features of dizziness and instability, therefore, clinical and instrumental examination of the patient is of particular importance. Read More

BMJ Case Rep 2021 Jan 11;14(1). Epub 2021 Jan 11.

General Medicine, Chiba University Hospital, Chiba, Japan.

Ear Nose Throat J 2021 Apr 9;100(2_suppl):163S-168S. Epub 2020 Dec 9.

Department of Otolaryngology-Head and Neck Surgery, 12967Nara Medical University, Kashihara, Nara, Japan.

Objectives: In the present report, we aimed to investigate the impact of the coronavirus disease (COVID-19) pandemic on vertigo/dizziness outpatient cancellations in Japan.

Methods: We examined 265 vertigo/dizziness outpatients at the ear, nose, and throat department of the Nara Medical University between March 01, 2020, and May 31, 2020, during the COVID-19 pandemic in Japan. We also focused on 478 vertigo/dizziness outpatients between March 01, 2019, and May 31, 2019, before the COVID-19 pandemic, to compare the number of cancellations between these 2 periods. Read More

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2020 Nov;34(11):990-992;998

Department of Otolaryngology Head and Neck Surgery，Dalian Municipal Central Hospital，Dalian，116000，China.

To detect the impairment degree and recovery process of the semicircular canals of patients with vestibular neuritis（VN） by video head impulse test（vHIT） over different periods. The clinical data of patients with VN, who were diagnosed by Vertigo clinic'physicians in the Department of ENT, Dalian Municipal Central Hospital from Sept. 2018 to Sept. Read More

Laryngorhinootologie 2021 03 9;100(3):195-201. Epub 2020 Nov 9.

Klinik für Hals-, Nasen-, Ohrenheilkunde, Campus Benjamin Franklin, Charité Universitätsmedizin Berlin, Berlin, Deutschland.

Introduction: The vestibular neuropathy (VN) is a frequently diagnosed, acute peripheral vestibular form of vertigo. Typical symptoms are spinning vertigo, ipsilateral tendency to fall with standing and gait insecurity, and vegetative side effects. Epidemiological studies of VN in the general population are rare and the little existing literature varies in results. Read More

Sci Rep 2020 10 26;10(1):18224. Epub 2020 Oct 26.

Department of Otorhinolaryngology-Head & Neck Surgery, Hallym University College of Medicine, Anyang, Korea.

The association of thyroid disease and Ménière's disease would suggest that both are autoimmune diseases. This study aimed to investigate the relation of goiter, hypothyroidism, thyroiditis, hyperthyroidism, and autoimmune thyroiditis with Ménière's disease. The Korean National Health Insurance Service-Health Screening Cohort data from 2002 through 2015 were used. Read More

Brain 2020 10;143(10):e82

Molecular Medicine Laboratory, Concord Repatriation General Hospital, Sydney, NSW, Australia.

Neurology 2020 12 10;95(22):e2988-e3001. Epub 2020 Sep 10.

From the Cantonal Hospital Baden (A.A.T.); Faculty of Medicine (A.A.T., C.J.B., K.P.W.), University of Zurich; Departments of Neurology (A.A.T., C.J.B., E.B., K.P.W.), Ophthalmology (C.J.B., K.P.W.), and Otorhinolaryngology (C.J.B.), University Hospital Zurich; and Clinical Neuroscience Center (A.A.T., C.J.B., K.P.W.), Zurich, Switzerland.

Objective: To test the hypothesis that patterns of semicircular canal (SCC) and otolith impairment in unilateral vestibular loss depend on the underlying disorders, we analyzed peripheral-vestibular function of all 5 vestibular sensors.

Methods: For this retrospective case series, we screened the hospital video-head-impulse test database (n = 4,983) for patients with unilaterally impaired SCC function who also received ocular vestibular-evoked myogenic potentials and cervical vestibular-evoked myogenic potentials (n = 302). Frequency of impairment of vestibular end organs (horizontal/anterior/posterior SCC, utriculus/sacculus) was analyzed with hierarchical cluster analysis and correlated with the underlying etiology. Read More

Phys Ther 2020 10;100(11):2009-2022

Dizziness and Balance Center, Emory Healthcare, Emory University.

Objective: The purpose of this study was to determine factors associated with rehabilitation outcomes following vestibular rehabilitation (VR).

Methods: In this prospective cohort study, 116 patients who completed at least 2 supervised sessions participated. Patient characteristics and comorbidities were recorded. Read More

Zh Nevrol Psikhiatr Im S S Korsakova 2020 ;120(6):125-130

Sechenov First Moscow State Medical University, Moscow, Russia.

Vestibular vertigo is most often caused by benign paroxysmal positional vertigo (BPPV), Meniere's disease, vestibular neuritis, vestibular migraine or stroke. Features, diagnosis and treatment of vestibular vertigo in patients with these diseases are discussed. The authors analyze common diagnostic errors based on the data of 700 outpatients (205 men and 495 women, aged 25-88 years, mean age 55 years). Read More

Otol Neurotol 2020 08;41(7):964-971

Department of Otolaryngology-Head and Neck Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Objective: To examine the importance of video head impulse test parameter for recovery of symptoms in acute vestibular neuritis (AVN).

Study Design: Prospective study.

Setting: Tertiary referral hospital. Read More

Otol Neurotol 2020 08;41(7):e952-e960

Division of Audiology and Neurootology, Department of Oto-Rhino-Laryngology, University of Basel Hospital, Basel, Switzerland.

Objective: Previous studies reported that balance deficits in pitch (sagittal) and roll (lateral) planes during stance and gait after onset of an acute unilateral peripheral vestibular deficit (aUPVD) due to vestibular neuritis are weakly correlated with deficits in commonly explored lateral canal vestibular ocular reflex (VOR) responses. Theoretically, stronger correlations with roll and pitch balance deficits could be expected for vertical canal VOR responses. Therefore, we investigated these correlations. Read More

Vestn Otorinolaringol 2020 ;85(3):32-35

Sverzhevsky Research Clinical Institute of Otorhinolaryngology of the Moscow Healthcare Department, Moscow, Russia.

Objective: To identify etiology, clinical symptoms of bilateral vestibulopathy (BV) depending on etiology.

Results: Idiopathic BV was identifies in one third of patients. The most common identified reasons are Meniere's disease, meningitis and ototoxicity. Read More

Eur Arch Otorhinolaryngol 2020 Nov 29;277(11):3205-3212. Epub 2020 May 29.

Fondazione Santa Lucia IRCCS, Rome, Italy.

Purpose: Evaluate the potential clinical application of the Suppression Head Impulse Paradigm (SHIMP) in evaluating the vestibulo-saccadic interaction in patients with vestibular neuritis (VN).

Methods: A retrospective study was performed. Fifteen patients diagnosed with unilateral VN were identified from a database of ENT vestibular clinic from January 2011 to February 2020. Read More

Neurology 2020 06 4;94(23):1042-1047. Epub 2020 May 4.

From the Department of Neurology (J.-Y.C., J.-S.K.), Seoul National University College of Medicine; and Dizziness Center, Clinical Neuroscience Center, Department of Neurology (J.-Y.C., J.-S.K.), and Research Administration Team (H.-J.K.), Seoul National University Bundang Hospital, Seongnam, Korea.

Int J Pediatr Otorhinolaryngol 2020 Jul 21;134:110048. Epub 2020 Apr 21.

Department of Otorhinolaryngology, Centro Hospitalar de Vila Nova de Gaia/Espinho, Rua Conceição Fernandes, S/n, 4434-502, Vila Nova de Gaia, Porto, Portugal.

Acute vestibular syndrome is most often caused by vestibular neuritis or stroke, although demyelinating diseases may be responsible for 4% of all AVS episodes. The authors present the case of a previously healthy 17-year-old female patient complaining of spontaneous vertigo and right-sided hearing loss. Otoneurological examination suggested a peripheral vestibular cause and video head impulse test revealed a reduced vestibulo-ocular reflex gain. Read More

Otol Neurotol 2020 07;41(6):836-842

Department of Otolaryngology-Head and Neck Surgery, Eulji University College of Medicine, Daejeon.

Objective: To assess factors predicting vestibular neuritis (VN) prognosis at an early stage.

Study Design: Retrospective chart review.

Setting: University hospital. Read More

Acta Otorhinolaryngol Ital 2020 Feb;40(1):19-25

ENT Division, University of Eastern Piedmont, Novara, Italy.

Endokrynol Pol 2020 ;70(1):76-86

Department of Otorhinolaryngology and Laryngological Oncology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Zabrze, Poland.

Vertigo and balance disorders are common symptoms reported by approximately 15-20% of the adult population worldwide. For many years thyroid diseases have been suspected as the cause of vertigo by ENT physicians. Almost every patient hospitalised due to severe vertigo is investigated for thyroid disease as a suspected cause of acute vestibulopathy. Read More

CMAJ 2020 02;192(8):E182-E186

Department of Emergency Medicine (Johns), University of Ottawa, Ottawa, Ont.; Department of Emergency Medicine (Quinn), Stanford University, Stanford, Calif.

Rofo 2020 Sep 20;192(9):854-861. Epub 2020 Feb 20.

Diagnostic and Interventional Radiology, University Hospital Ulm, Germany.

Purpose:  Sudden unilateral peripheral vestibular deficit is mostly termed vestibular neuritis (VN), even if its cause or the exact location of the lesion remains unclear. Thus, therapy is mostly symptomatic. We aimed to prove if there is peripheral atrophy after VN with persistent canal paresis. Read More

Brain 2020 02;143(2):480-490

Department of Neurology, School of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.

Ataxia, causing imbalance, dizziness and falls, is a leading cause of neurological disability. We have recently identified a biallelic intronic AAGGG repeat expansion in replication factor complex subunit 1 (RFC1) as the cause of cerebellar ataxia, neuropathy, vestibular areflexia syndrome (CANVAS) and a major cause of late onset ataxia. Here we describe the full spectrum of the disease phenotype in our first 100 genetically confirmed carriers of biallelic repeat expansions in RFC1 and identify the sensory neuropathy as a common feature in all cases to date. Read More

Brain 2020 02;143(2):386-390

Division of Neuro-otology & Neurogenetics, Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, USA.