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    325 results match your criteria Vesicular Palmoplantar Eczema

    1 OF 7

    Dupilumab in the Treatment of Dyshidrosis: A Report of Two Cases.
    J Drugs Dermatol 2018 Mar;17(3):355-356
    Dupilumab (Dupixent, Regeneron Pharmaceuticals and Sanofi Genzyme) is a novel biologic medication recently approved by the FDA for the treatment of moderate-to-severe atopic dermatitis in adults who have not achieved adequate control with topical medications. Dyshidrotic eczema is a distinct entity, often considered on the spectrum of atopic dermatitis, that primarily effects the palms and soles; it is often associated with considerable morbidity yet is frequently challenging to treat. We report two cases of recalcitrant dyshidrotic eczema treated successfully with dupilumab at standard dosing. Read More

    Dyshidrotic Bullous Pemphigoid: Case Report and Review of Literature.
    J Cutan Med Surg 2018 Mar 1:1203475418763544. Epub 2018 Mar 1.
    1 Faculty of Medicine, Dalhousie University, Halifax, NS, Canada.
    Background: Dyshidrotic pemphigoid (DP) is a rare variant of bullous pemphigoid (BP) that affects the hands and feet and may resemble an acute vesicular eczema. While it can remain confined to hands and feet, spread that involves the entire body is described. BP and DP are associated with autoantibodies directed against hemidesmosomal proteins BP180 (collagen XVII) and BP230 (dystonin), which are transmembrane and intracellular proteins in the basement membrane zone, respectively. Read More

    Impetiginized Dyshidrotic Eczema.
    Open Access Maced J Med Sci 2017 Jul 19;5(4):539-540. Epub 2017 Jul 19.
    Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Friedrichstrasse 41, 01067, Dresden, Germany.
    A 16 years old female patient, affected by atopic dermatitis and rhinoconjunctivitis allergica since childhood, requested a dermatologic consultation for lesions which had appeared after 3 months of local treatment with clobethasole propionate. The histological analysis confirmed the diagnosis of dyshidrotic eczema and the microbiological smears demonstrated a significant infection with . The risk of developing corticosteroids' side-effects depends on the potency of the product, extended period of use and the volume of product applied. Read More

    Dermatitis of the Foot: Epidemiologic and Clinical Features in 389 Children.
    Pediatr Dermatol 2017 Sep 21;34(5):535-539. Epub 2017 Jul 21.
    Dermatology Department, Valencia University General Hospital, Valencia, Spain.
    Background/objectives: Footwear dermatitis is a form of contact dermatitis resulting from exposure to shoes. There have been only small studies regarding foot contact dermatitis in children. The present study was undertaken to define the prevalence and epidemiologic and clinical features of shoe dermatitis in children. Read More

    Dyshidrotic Eczema and Its Relationship to Metal Allergy.
    Curr Probl Dermatol 2016 30;51:80-5. Epub 2016 Aug 30.
    Department of Dermatology, National Defense Medical College, Tokorozawa, Japan.
    Dyshidrotic eczema, also known as dyshidrotic dermatitis or pompholyx, is characterized by pruritic, small tense vesicles mainly on the palmoplantar region and lateral and ventral surfaces of the fingers. While its etiology appears to be related to sweating, as dyshidrotic eczema often occurs in an individual with hyperhidrosis, and the spring allergy season, histologic examination shows an eczematous reaction around the sweat ducts which is not associated with abnormalities of the sweat ducts. More recently, the nomenclature of 'acute and recurrent vesicular hand dermatitis' has been proposed to reflect clinical features of dyshidrotic eczema. Read More

    Atypical Forms of Hand, Foot, and Mouth Disease: A Prospective Study of 47 Italian Children.
    Pediatr Dermatol 2016 Jul 13;33(4):429-37. Epub 2016 Jun 13.
    Dermatology Unit, Department of Specialistic, Diagnostic and Experimental Medicine, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
    Background: Atypical forms of hand, foot, and mouth disease (HFMD) caused by coxsackievirus A6 have been reported in recent years. High fever and severe cutaneous lesions are common, whereas neurologic complications are rare. Eczematous areas of patients with atopic dermatitis show more lesions. Read More

    Altered Levels of Serum Zinc and Cadmium in Patients with Chronic Vesiculobullous Hand and Feet Dermatitis.
    Dermatol Res Pract 2016 6;2016:3284937. Epub 2016 Apr 6.
    Department of Radiodiagnosis, King George Medical University, Lucknow, Uttar Pradesh 226003, India.
    Micronutrients serve many important functions in our body and altered levels of heavy and trace metals are associated with cutaneous and systemic disorders. Vesicular palmoplantar eczema is an entity whose etiopathogenesis is a mystery. In this prospective case-noncase study blood levels of Zinc and Cadmium in 37 patients of chronic vesiculobullous hand dermatitis were estimated and compared with 40 noncases with similar age and gender distributions. Read More

    Classification of hand eczema.
    J Eur Acad Dermatol Venereol 2015 Dec 15;29(12):2417-22. Epub 2015 Sep 15.
    Department of Social Medicine, Occupational and Environmental Dermatology, University Hospital, Heidelberg, Germany.
    Background: Classification of hand eczema (HE) is mandatory in epidemiological and clinical studies, and also important in clinical work.

    Objectives: The aim was to test a recently proposed classification system of HE in clinical practice in a prospective multicentre study.

    Methods: Patients were recruited from nine different tertiary referral centres. Read More

    Pseudocheckerboard pattern: an interesting histopathological finding in mechanic's hands.
    J Cutan Pathol 2016 Jan 30;43(1):5-11. Epub 2015 Sep 30.
    Division of Dermatology, Department of Medicine of Sensory and Motor Organs, Faculty of Medicine, Tottori University, Yonago, Japan.
    Background: Mechanic's hands are a well-known symptom often associated with dermatomyositis and are similar to hand eczema clinically. Histopathology of them usually shows hyperkeratosis, focal parakeratosis, psoriasiform acanthosis, basal vacuolar changes and necrotic keratinocytes in the epidermis and upper dermal mucin deposition. However, there have been few comparative histopathologic evaluations of mechanic's hands and palmoplantar eczema. Read More

    Dyshidrosis is a risk factor for herpes zoster.
    J Eur Acad Dermatol Venereol 2015 Nov 27;29(11):2177-83. Epub 2015 Apr 27.
    Graduate Institute of Clinical Medical Science and School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan.
    Background: Endogenous factors such as stress-induced immune system reactivity were also associated with dyshidrosis. Herpes zoster (HZ) incidence has been demonstrated to increase with immune deficiencies. Therefore, a relationship between dyshidrosis and HZ may exist. Read More

    A Severe Case of Recalcitrant Pompholyx.
    J Cutan Med Surg 2015 Sep-Oct;19(5):494-7. Epub 2015 Apr 15.
    The Ottawa Hospital, Ottawa, ON, Canada.
    Background: Pompholyx is an inflammatory vesiculobullous skin disease of the hands and feet belonging to the spectrum of eczema.

    Objective: To report a severe case of pompholyx, its clinical presentation, and its management.

    Methods: A medical chart review was conducted on a patient with this condition. Read More

    The key role of aquaporin 3 and aquaporin 10 in the pathogenesis of pompholyx.
    Med Hypotheses 2015 May 11;84(5):498-503. Epub 2015 Feb 11.
    Department of Dermatology, Case Western Reserve University, USA; The Murdough Family Center for Psoriasis, Cleveland, OH 44106, USA. Electronic address:
    Pompholyx remains a chronic skin affliction without a compelling pathophysiological explanation. The disease is characterized by the sudden onset of vesicles exclusively in the palms and soles which generally resolves. However, the disease may progress and the vesicles may expand and fuse; with chronicity there is deep fissuring. Read More

    A surprising case of Mycobacterium avium complex skin infection in an immunocompetent patient.
    J Drugs Dermatol 2014 Dec;13(12):1491-3
    An acute inflammatory nodule of unknown etiology can pose a formidable diagnostic challenge. Here, we highlight the importance of including Mycobacterium avium intracellulare complex (MAC) and other atypical mycobacterial infections in the differential diagnosis of a cutaneous nodule in an immunocompetent individual. We also explore the implications of eczema in the development of a mycobacterial infectious process. Read More

    Remarkable improvement of relapsing dyshidrotic eczema after treatment of coexistant hyperhidrosis with oxybutynin.
    Dermatol Ther 2014 Nov-Dec;27(6):365-8. Epub 2014 Jul 14.
    Department of Dermatology and Venereology, Hospital "Andreas Sygros", Athens, Greece.
    Dyshidrotic hand eczema is a common condition, which can be resistant to various treatments. Although a number of etiologic factors are involved in the pathogenesis of dyshidrotic eczema, hyperhidrosis is assumed to play a significant role. Oxybutynin is an alternative treatment for hyperhidrosis. Read More

    Pompholyx of the hands after intravenous immunoglobulin therapy for clinically isolated syndrome: a paediatric case.
    Int J Immunopathol Pharmacol 2014 Jan-Mar;27(1):127-30
    Institute of Dermatology, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
    Pompholyx is a common eruption of small vesicles on the palms, soles, and/or lateral aspects of the fingers. It has a multifactorial etiology, including genetic determinants, allergy to metals, and id reaction; rarely it is a drug-related side effect. We report a paediatric case of pompholyx of the hands related to the intravenous immunoglobulin (IVIG) therapy for Clinically Isolated Syndrome (CIS). Read More

    A comparison of inflammatory mediator expression between palmoplantar pustulosis and pompholyx.
    J Eur Acad Dermatol Venereol 2013 Dec 26;27(12):1559-65. Epub 2013 Jun 26.
    Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.
    Background: Both palmoplantar pustulosis (PPP) and pompholyx are clinically characterized by acute eruptions of vesicles or pustules on the palms or soles.

    Objectives: This study aims to compare the expression of certain inflammatory mediator genes and proteins between patients with PPP and pompholyx using skin tissue samples.

    Methods: Skin biopsies obtained from lesional skin from patients with PPP (n = 7) and pompholyx (n = 5) were analysed by quantitative RT-PCR to measure the mRNA levels of nine genes, including IL-4, IL-8, IL-9, IL-17, IL-22, IFN-γ, CCL-20, granzyme and perforin. Read More

    Dyshidrotic eczema associated with the use of IVIg.
    BMJ Case Rep 2013 Feb 15;2013. Epub 2013 Feb 15.
    Department of Neurology, Sakarya University Faculty of Medicine, Sakarya, Turkey.
    Intravenous immunoglobulin (IVIg) treatment is highly effective for autoimmune diseases including myasthenia gravis. Recovery is observed at approximately. 75% of myasthenia gravis patients through IVIg treatment. Read More

    Increase in vesicular hand eczema after house dust mite inhalation provocation: a double-blind, placebo-controlled, cross-over study.
    Contact Dermatitis 2013 Feb 10;68(2):76-85. Epub 2012 Oct 10.
    Department of Dermatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
    Background: It is unclear whether the respiratory tract is involved in eliciting or aggravating eczematous lesions in patients with vesicular hand eczema. Objectives. To investigate the effect of inhalation of house dust mite (HDM) on vesicular hand eczema. Read More

    Keratolysis exfoliativa (dyshidrosis lamellosa sicca): a distinct peeling entity.
    Br J Dermatol 2012 Nov 5;167(5):1076-84. Epub 2012 Oct 5.
    Centre for Blistering Diseases, Department of Dermatology, University of Groningen, University Medical Centre Groningen, Hanzeplein 1, 9700 RB Groningen, the Netherlands.
    Background: Keratolysis exfoliativa (KE), also known as dyshidrosis lamellosa sicca, is a palmoplantar dermatosis characterized by air-filled blisters and collarette desquamation. It has been regarded as a subtype of dyshidrotic eczema, a fungal infection or a dermatophytid reaction. KE may also resemble acral peeling skin syndrome and localized epidermolysis bullosa simplex. Read More

    Diagnosis and treatment of hand dermatitis.
    Adv Skin Wound Care 2012 Aug;25(8):371-80; quiz 381-2
    Toronto Regional Wound Clinic, Women's College Hospital, Toronto, Ontario, Canada.
    Purpose: To enhance the learner's competence with knowledge of hand dermatitis.

    Target Audience: : This continuing education activity is intended for physicians and nurses with an interest in skin and wound care.

    Objectives: After participating in this educational activity, the participant should be better able to: 1. Read More

    Retrospective long-term follow-up in patients with chronic palmoplantar dermatoses after good response to bath PUVA therapy.
    J Dtsch Dermatol Ges 2012 Nov 28;10(11):814-8. Epub 2012 Jun 28.
    Research Unit for Photodermatology, Department of Dermatology and Venereology, Medical University of Graz, Austria.
    Background: Numerous studies have confirmed the short-term effectiveness of 8-methoxypsoralen bath PUVA therapy in patients with chronic palmoplantar dermatoses; however, little is known about long-term results.

    Patients And Methods: In this retrospective study we examined the long-term results in 79 patients (mean age: 48 years) with chronic palmoplantar dermatoses who were treated with bath PUVA three times a week over an 8-year period. A good clinical response (a reduction of more than 50% of the skin lesions) occurred after a mean of 23 treatments and a mean cumulative UVA dose of 39 J/cm(2) in 51 patients (65%). Read More

    Histological differentiation between palmoplantar pustulosis and pompholyx.
    J Eur Acad Dermatol Venereol 2013 Jul 13;27(7):889-93. Epub 2012 Jun 13.
    Department of Dermatology, Seoul National University Boramae Hospital Seoul, Seoul, Korea.
    Background: Palmoplantar pustulosis (PPP) is a chronic and intensely inflammatory skin disease with pustules, erythema and scaling localized to the palms and soles. Pompholyx is characterized by recurrent crops of vesicles on the lateral aspects of the fingers and the palms and soles. Because both PPP and pompholyx share similar clinical and histological features, it is difficult to differentiate between these two diseases even for dermatologists. Read More

    [Tap water iontophoresis].
    Hautarzt 2012 Jun;63(6):462-8
    Klinik für Dermatologie und Allergologie, Klinikum Oldenburg, Rahel-Straus-Str. 10, 26133, Oldenburg, Deutschland.
    Since 1968, tap water iontophoresis has been employed as the method of choice for treating palmoplantar hyperhidrosis. Special electrodes also allow treatment of axillary hyperhidrosis. Tap water iontophoresis also can extend symptom -free intervals in dyshidrotic palmar eczema. Read More

    A case of acquired Zinc deficiency.
    Dermatol Online J 2012 May 15;18(5). Epub 2012 May 15.
    Boston University School of Medicine, Department of Dermatology, Boston, Massachusetts, USA.
    We report a case of adult-onset acquired zinc deficiency after bariatric surgery. Zinc deficiency may be inherited in the form of acrodermatitis enteropathica or acquired by low nutritional intake, malabsorption, excessive loss of zinc, or a combination of these factors. Read More

    Vesicular palmoplantar pityriasis rosea.
    Skinmed 2012 Mar-Apr;10(2):116-8
    Department of Dermatology, Venereology & Leprology, Gian Sagar Medical College & Hospital, Ram Nagar, Banur, Patiala, India.
    A 16-year-old young man presented with intensely itchy erythematous dermatitis on the body for 1 week and vesicular lesions on the palms and soles for 4 to 5 days. Lesions on the palms and soles were accompanied by severe burning and itching. The patient gave a history of sore throat and fever, 1 week prior to the onset of lesions. Read More

    Severe dyshidrotic eczema after intravenous immunoglobulin therapy for Kawasaki syndrome.
    Pediatr Dermatol 2013 May-Jun;30(3):e30-1. Epub 2012 Feb 3.
    Department of Dermatology, Fukushima Medical University, Fukushima, Japan.
    Dyshidrotic eczema is one of the rare cutaneous adverse effects of intravenous immunoglobulin therapy, usually seen in adults. We herein report the first pediatric case of severe dyshidrotic eczema occurring after intravenous immunoglobulin therapy for Kawasaki syndrome. Read More

    [Pompholyx-like reactions occurring early in treatment of severe atopic dermatitis in children and adolescence].
    Arerugi 2011 Nov;60(11):1543-9
    Division of Allergy, Department of Medical Specialties, National Center for Child Health and Development.
    Background: Pompholyx-like reactions may develop for aggressive atopic dermatitis treatments in the incipient phase despite of improvement of other skin symptoms.

    Methods: Eighty-nine patients admitted to National Center for Child Health and Development for treatment of atopic dermatitis between April 2007 and March 2009 were recruited.

    Results: Pompholyx-like reactions were seen in thirteen out of eighty-nine patients between 4 and 32 (mean 16. Read More

    Shape and configuration of skin lesions: grouped herpetiform.
    Clin Dermatol 2011 Sep-Oct;29(5):509-10
    Department of Endocrinological and Medical Sciences, Section of Dermatology, University of Genoa,Viale Benedetto XV No. 7, 16132 Genova, Italy.
    Lesions that may present in a grouped way include diseases with grouped vesicles such as dyshidrosis, nummular dermatitis, herpes simplex, and herpes zoster; diseases with grouped vesicobullae such as dermatitis herpetiformis, herpes gestationis, subacute lupus erythematosus in the bullous variant, and pemphigus herpetiformis; and diseases with grouped pustules such as pustular psoriasis, dermatitis continua of Hallopeau, and impetigo herpetiformis. Read More

    Diagnosing chronic hand eczema by an algorithm: a tool for classification in clinical practice.
    Clin Exp Dermatol 2011 Aug;36(6):595-601
    Department of Dermatology and Allergology, Ludwig Maximilian University, Munich, Germany.
    Background: Diagnostic classification of chronic hand eczema (CHE) represents a major clinical and taxonomic challenge because of its wide aetiological and clinical heterogeneity.

    Aim: To develop an algorithm for the diagnosis and classification of CHE.

    Methods: Well-defined aetiological, clinical and morphological criteria of CHE were arranged graphically in a diagnostic hierarchy, and validated in 137 German patients with hand eczema. Read More

    Pompholyx and eczematous reactions associated with intravenous immunoglobulin therapy.
    J Am Acad Dermatol 2012 Feb 20;66(2):312-6. Epub 2011 May 20.
    Department of Dermatology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
    Introduction: Intravenous immunoglobulin (IVIG) is used to treat many inflammatory and autoimmune disorders and although generally well tolerated, cutaneous side effects occur.

    Objective: We reviewed reports of pompholyx and eczematous reactions associated with IVIG.

    Methods: A literature search was performed using the PubMed and MEDLINE databases with the search terms "intravenous immunoglobulin pompholyx," "intravenous immunoglobulin eczema," "intravenous immunoglobulin cutaneous adverse effects," "intravenous immunoglobulin cutaneous effects," "intravenous immunoglobulin skin effects," and "intravenous immunoglobulin adverse effects. Read More

    A systematic approach to systemic contact dermatitis and symmetric drug-related intertriginous and flexural exanthema (SDRIFE): a closer look at these conditions and an approach to intertriginous eruptions.
    Am J Clin Dermatol 2011 Jun;12(3):171-80
    Department of Dermatology, Sunnybrook Hospital, University of Toronto, Ontario, Canada.
    Systemic contact dermatitis is a condition that occurs when an individual sensitized to a contact allergen is exposed to that same allergen or a cross-reacting molecule through a systemic route. Systemic exposure to allergens can include transcutaneous, transmucosal, oral, intravenous, intramuscular, and inhalational routes. Baboon syndrome is perhaps the most recognizable form of systemic contact dermatitis, presenting with diffuse, well demarcated erythema of the buttocks, upper inner thighs, and axillae. Read More

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