10,225 results match your criteria Vesicoureteral Reflux


Risk factors for obstructive complications after endoscopic correction of vesico-ureteral reflux using polyacrylate polyalcohol copolymer.

Medicine (Baltimore) 2020 May;99(22):e20386

Samara Regional Clinical Hospital, Samara, Russian Federation.

Use of polyacrylate-polyalcohol copolymer (PPC) after endoscopic correction (EC) of vesico-ureteral reflux (VUR) is highly effective but is associated with a higher risk of obstructive complications (OC) compared with other implants. We undertook a STROBE compliant retrospective investigation and studied the OC risk factors to increase the practical safety of PPC.Overall, 798 patients (464 [58. Read More

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http://dx.doi.org/10.1097/MD.0000000000020386DOI Listing

EAU-ESPU guidelines recommendations for daytime lower urinary tract conditions in children.

Eur J Pediatr 2020 May 29. Epub 2020 May 29.

Division of Pediatric Urology, Department of Urology, School of Medicine, Hacettepe University, Ankara, Turkey.

The objective is to review the literature related to lower urinary tract (LUT) conditions in children to conceptualize general practice guidelines for the general practitioner, pediatrician, pediatric urologist, and urologist. PubMed was searched for the last 15-year literature by the committee. All articles in peer-review journal-related LUT conditions (343) have been retrieved and 76 have been reviewed extensively. Read More

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http://dx.doi.org/10.1007/s00431-020-03681-wDOI Listing

[Aphallia - report of two cases].

Urologe A 2020 May 29. Epub 2020 May 29.

Klinik für Kinderchirurgie und Kinderurologie, Kinderkrankenhaus Amsterdamer Straße, Amsterdamer Straße 59, 50735, Köln, Deutschland.

Aphallia is an extremely rare congenital malformation of unknown cause. The incidence is reported in the literature to be 1 in 10-30 million live births. Almost 100 cases have been described to date. Read More

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http://dx.doi.org/10.1007/s00120-020-01244-3DOI Listing

A Particular Form of "Urolithiasis" in a Toddler.

Pediatrics 2020 Jun;145(6)

Department of Woman, Child and General and Specialist Surgery, Università degli Studi della Campania Luigi Vanvitelli, Naples, Italy.

Milk of calcium is a viscous colloidal suspension of calcium salts that forms in dilated cysts or cavities. We present, for the first time in literature, a toddler with isolated milk of calcium and treated with a conservative approach. A boy with a history of one urinary tract infection and recurrent fever without vesicoureteral reflux showed at the age of 14 months a left obstructive staghorn stone. Read More

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http://dx.doi.org/10.1542/peds.2019-3190DOI Listing

Contrast-enhanced voiding urosonography: A new, radiation-free, alternative method for imaging of urinary bladder and urethra in healthy dogs.

Vet Radiol Ultrasound 2020 May 27. Epub 2020 May 27.

School of Veterinary Medicine, Aristotle University of Thessaloniki, Stavrou Voutira, Thessaloniki, Greece.

Contrast-enhanced voiding urosonography (CE-VUS) has been generally considered as a promising tool to diagnose vesicoureteral reflux and abnormalities in lower urinary tract in human patients, especially in children. The purpose of this prospective study is to evaluate the quality of images of the urinary bladder and urethra obtained by CE-VUS using a second-generation ultrasound contrast agent (SonoVue®) in healthy dogs and to investigate the safety profile of SonoVue® after intravesical administration. Eighty-four CE-VUS examinations with SonoVue® were successfully performed in both unsedated (39/84) and sedated (45/84) dogs. Read More

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http://dx.doi.org/10.1111/vru.12867DOI Listing

Serum creatinine levels in cases of posterior urethral valve: 29 years experience of a pediatric urology reference center.

Low Urin Tract Symptoms 2020 May 19. Epub 2020 May 19.

Department of Urology, University of Health Sciences, Sultan Abdülhamid Han Education and Research Hospital, Istanbul, Turkey.

Objectives: The aim of this retrospective study is to describe the importance of serum creatinine levels for the long-term renal outcome in cases of posterior urethral valve.

Methods: Records of 94 patients who underwent cystoscopic valve ablation were evaluated retrospectively. Demographic variables, radiologic findings, and serum creatinine levels were recorded. Read More

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http://dx.doi.org/10.1111/luts.12316DOI Listing

Parental perception of bladder spasms and hematuria after surgery for vesicoureteral reflux: A prospective multicenter study.

J Pediatr Urol 2020 Apr 30. Epub 2020 Apr 30.

Virginia Commonwealth University, Division of Urology, Richmond, VA, USA.

Introduction: Anti-reflux surgery success has been well-documented in the literature. Little data exists about the characterization of the child's symptoms regarding pain, bladder spasms, and hematuria following these procedures. These symptoms may affect the choice of surgery for families and providers. Read More

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http://dx.doi.org/10.1016/j.jpurol.2020.04.024DOI Listing

Utility of the Society for Fetal Urology and Anteroposterior Pelvic Diameter Grading Systems for Estimating the Time to Resolution of Isolated Hydronephrosis: A Single-Center Study.

J Urol 2020 May 18:101097JU0000000000001140. Epub 2020 May 18.

Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Korea.

Purpose: We aimed to compare the Society for Fetal Urology (SFU) and Anteroposterior Pelvic Diameter (APPD) classification systems in predicting the time to resolution of isolated hydronephrosis.

Materials And Methods: We retrospectively reviewed isolated hydronephrosis cases prenatally detected and postnatally diagnosed between 1994 and 2018. Other urinary tract anomalies and vesicoureteral reflux were excluded. Read More

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http://dx.doi.org/10.1097/JU.0000000000001140DOI Listing

Variation in ureteric re-implantation for Australian children.

ANZ J Surg 2020 May 17. Epub 2020 May 17.

Department of Paediatric Surgery, Women's and Children's Hospital, Adelaide, South Australia, Australia.

Background: Management options for vesicoureteric reflux are numerous, increasingly diversifying and debated. There is longstanding anecdotal opinion of inexplicable regional variation in vesicoureteric reflux management in Australia. This study investigates temporal trends in ureteric re-implantation for children, and variation between states and territories. Read More

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http://dx.doi.org/10.1111/ans.15995DOI Listing

Neurophysiological control of urinary bladder storage and voiding-functional changes through development and pathology.

Authors:
Youko Ikeda

Pediatr Nephrol 2020 May 15. Epub 2020 May 15.

School of Medicine, Renal-Electrolyte Division, University of Pittsburgh, A1219 Scaife Hall, Pittsburgh, PA, 15261, USA.

The effective storage of urine and its expulsion relies upon the coordinated activity of parasympathetic, sympathetic, and somatic innervations to the lower urinary tract (LUT). At birth, all mammalian neonates lack the ability to voluntary regulate bladder storage or voiding. The ability to control urinary bladder activity is established as connections to the central nervous system (CNS) form through development. Read More

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http://dx.doi.org/10.1007/s00467-020-04594-4DOI Listing

Proprietary non-animal stabilized hyaluronic acid/dextranomer gel (NASHA/Dx) for endoscopic treatment of grade IV vesicoureteral reflux: Long-term observational study.

J Pediatr Urol 2020 Apr 13. Epub 2020 Apr 13.

Section of Urology, University Children's Hospital, Uppsala, Sweden.

Background: Since 1993, children aged >1 year with persistent grade III-V vesicoureteral reflux (VUR) and febrile urinary tract infections (UTIs) attending Uppsala University Hospital have undergone endoscopic injection with proprietary non-animal stabilized hyaluronic acid/dextranomer gel (NASHA/Dx; Deflux®).

Objective: Investigate long-term incidence of UTI, bladder dysfunction, ureteral reimplantation and overall clinical findings following endoscopic injection of NASHA/Dx.

Study Design: Children with grade IV VUR diagnosed by voiding cystourethrogram (VCUG) and dilating VUR persisting for >1 year were included in this study. Read More

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http://dx.doi.org/10.1016/j.jpurol.2020.04.008DOI Listing

Kidney triplication with ectopic ureterocele: a case report.

BMC Urol 2020 May 13;20(1):54. Epub 2020 May 13.

Urology Department, State Pediatric Medical University, 2 Litovskaya Street, build.2, St. Petersburg, Russian Federation, 194100.

Background: Kidney triplication is a rare urological abnormality. Association of triplex kidney and ureterocele is out of ordinary. Treatment of such patients usually implies heminephrureterectomy of the upper moiety. Read More

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http://dx.doi.org/10.1186/s12894-020-00625-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222539PMC

A quantitative grading system of vesicoureteral reflux by contrastenhanced voiding urosonography.

Med Ultrason 2020 Apr 14. Epub 2020 Apr 14.

Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Aims: Contrast-enhanced voiding urosonography (ceVUS) is a well-established imaging modality for the diagnosis of vesicoureteral reflux (VUR). However, discrepancies of grading diagnosis of VUR exist due to the qualitative grading criteria currently used in clinics. This study aimed to evaluate numerical markers for a quantitative VUR grading system. Read More

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http://dx.doi.org/10.11152/mu-2311DOI Listing

Assessment of the Etiologies and Outcomes of Antenatal Hydronephrosis in Patients at King Abdulaziz University Hospital.

Cureus 2020 Apr 10;12(4):e7615. Epub 2020 Apr 10.

Pediatrics, Faculty of Medicine, King Abdulaziz University, Jeddah, SAU.

Background Antenatal hydronephrosis (ANH) is the most common congenital abnormality. It is often detected during pregnancy through an antenatal ultrasound (US) examination. This condition is defined as the dilatation of the renal pelvis and/or calyces in neonates. Read More

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http://dx.doi.org/10.7759/cureus.7615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213646PMC

Massively Dilated Lower Pole Ectopic Megaureter with Involuted Lower Pole Renal Moiety and Collecting System: An Exception to the Meyer-Weigert Rule.

Cureus 2020 Apr 7;12(4):e7577. Epub 2020 Apr 7.

Surgery/Pediatric Urology, University of Nebraska Medical Center, Omaha, USA.

Duplicated collecting systems have a predictable draining pattern that is described by the Meyer-Weigert rule. When there are abnormalities associated with duplicating collecting systems, the upper pole moiety drains inferomedially (most commonly associated with obstruction), and the lower pole moiety drains superolaterally (most commonly associated with vesicoureteral reflux). We present a case of an infant with a duplicated collecting system that violates the Meyer-Weigert rule with lower pole megaureter with massive dilation, ectopic insertion, and associated involuted lower pole renal moiety. Read More

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http://dx.doi.org/10.7759/cureus.7577DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205359PMC

Antibiotic prophylaxis for prevention of urinary tract infections in the first year of life in children with vesicoureteral reflux diagnosed in the workup of antenatal hydronephrosis: a systematic review.

Pediatr Nephrol 2020 Apr 30. Epub 2020 Apr 30.

Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada.

Background: Children with antenatal hydronephrosis (ANH) diagnosed with postnatal asymptomatic vesicoureteral reflux (VUR) are thought to be at higher risk of urinary tract infection (UTI). As such, continuous antibiotic prophylaxis (CAP) is empirically recommended until age of toilet training; however, there are limited data to support this. The objective of this systematic review was to summarize the existing data and compare UTI rates in infants with asymptomatic VUR on CAP during the first year of life, to those not on CAP. Read More

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http://dx.doi.org/10.1007/s00467-020-04568-6DOI Listing
April 2020
2.856 Impact Factor

The changing resistance patterns of bacterial uropathogens in children.

Pediatr Int 2020 Apr 29. Epub 2020 Apr 29.

Ankara University School of Medicine, Department of Pediatrics, Division of Nephrology, Ankara, Turkey.

Background: Increased antimicrobial resistance is a problem in managing urinary tract infections (UTI). With this study, we assessed the resistance patterns of urinary isolates in children with UTI between January 2017 and January 2018.

Methods: A retrospective cohort study was conducted. Read More

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http://dx.doi.org/10.1111/ped.14270DOI Listing

Fulminant Emphysematous Pyelonephritis by Candida glabrata in a Kidney Allograft.

Nephron 2020 Apr 28:1-6. Epub 2020 Apr 28.

Nephrology Department, Hospital Universitario Fundación Alcorcón, Madrid, Spain.

Emphysematous pyelonephritis (EPN) is a rare and serious necrotizing infection that is potentially life-threatening. It has been seldom reported in kidney grafts and is usually caused by Gram-negative bacteria, with some case reports caused by anaerobic bacteria, and has been closely associated with poorly controlled diabetes mellitus (DM) and urinary tract structural abnormalities. There are no reports of EPN of fungal etiology in kidney grafts. Read More

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http://dx.doi.org/10.1159/000507259DOI Listing

Anterior urethral valves - A rare but challenging congenital pathology.

J Pediatr Urol 2020 Apr 4. Epub 2020 Apr 4.

Department of Surgery, Texas Children's Hospital, USA; Scott Department of Urology, Baylor College of Medicine, USA.

Background: Anterior urethral valves (AUV) and associated anterior urethral diverticula (AUD) are a rare cause of congenital lower urinary tract obstruction. They occur 25-30 times less frequently than posterior urethral valves (PUV) and historically tend to have a less aggressive presentation and outcome. However, due to the low incidence, little is known about management and long-term prognosis. Read More

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http://dx.doi.org/10.1016/j.jpurol.2020.03.024DOI Listing

Robotic Cystoprostatectomy With Intracorporeal Ileal Conduit Diversion in a Patient With Chronic Schistosomiasis.

Urology 2020 Apr 22. Epub 2020 Apr 22.

Department of Urology, University of Arizona College of Medicine Tucson, Tucson, AZ.

We present an interesting case of a patient who initially presented with urinary retention and was subsequently found to have bilateral grade 5 vesicoureteral reflux, a thick and noncompliant bladder, and biopsy proven ova of Schistosoma haematobium. This patient was subsequently managed surgically with a robotic radical cystoprostatectomy with intracorporeal ileal conduit diversion. Final pathology revealed chronic schistosomiasis with numerous ova present throughout the bladder. Read More

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http://dx.doi.org/10.1016/j.urology.2020.04.052DOI Listing

Vesicoureteral reflux is it important to find?

Pediatr Nephrol 2020 Apr 22. Epub 2020 Apr 22.

Pediatric Nephrology, Dialysis and Transplant Unit, Fondazione Ca' Granda IRCCS, Policlinico di Milano, Milan, Italy.

Vesico-ureteral reflux (VUR) has long been recognized as associated with urinary tract infections (UTIs), renal scarring, and chronic kidney disease (CKD). The concept of "reflux nephropathy" was born, whereby the VUR was considered the culprit, predisposing to recurrent UTIs and providing a conduit whereby the infection could ascend to the kidneys resulting in scarring and destruction. The more severe grades of reflux were thought to place the young child at particular risk of CKD. Read More

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http://dx.doi.org/10.1007/s00467-020-04573-9DOI Listing

Clinical Integration of Genome Diagnostics for Congenital Anomalies of the Kidney and Urinary Tract.

Clin J Am Soc Nephrol 2020 Apr 20. Epub 2020 Apr 20.

Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands

Revolutions in genetics, epigenetics, and bioinformatics are currently changing the outline of diagnostics and clinical medicine. From a nephrologist's perspective, individuals with congenital anomalies of the kidney and urinary tract (CAKUT) are an important patient category: not only is CAKUT the predominant cause of kidney failure in children and young adults, but the strong phenotypic and genotypic heterogeneity of kidney and urinary tract malformations has hampered standardization of clinical decision making until now. However, patients with CAKUT may benefit from precision medicine, including an integrated diagnostics trajectory, genetic counseling, and personalized management to improve clinical outcomes of developmental kidney and urinary tract defects. Read More

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http://dx.doi.org/10.2215/CJN.14661119DOI Listing
April 2020
4.613 Impact Factor

Endoscopic Dilatation of Stenotic Native Meatus of an Orthotopic Ureterocele: An Easy and Innovative Technique

Urol J 2020 04 20. Epub 2020 Apr 20.

Urology nephrology research center (UNRC), Shahid Labbafinejad medical center, Shahid Beheshti university of medical sciences, Tehran, Iran.

Background: This study presents initial experience in endoscopic meatal dilatation of obstructive ureterocele in adult patients.

Surgical Technique: During cystourethroscopy, we tried to find the orifice of ureterocele, passed a guide wire and introduce an 8 Fr ureteroscope in to the ureterocele orifice, going up to the renal pelvis as under vision dilatation of ureterocele meatus. Two Double-J stent were inserted and remained for six weeks to keep the meatus dilated. Read More

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http://dx.doi.org/10.22037/uj.v0i0.5808DOI Listing

Prevalence of Bladder and Bowel Dysfunction in Toilet-Trained Children With Urinary Tract Infection and/or Primary Vesicoureteral Reflux: A Systematic Review and Meta-Analysis.

Front Pediatr 2020 31;8:84. Epub 2020 Mar 31.

Division of Nephrology, Department of Pediatrics, ICMR Center for Advanced Research in Nephrology, All India Institute of Medical Sciences, New Delhi, India.

Urinary tract infection (UTI) in children leads to renal scarring in 10-15% of patients. Urinary tract anomalies and bladder and bowel dysfunction (BBD) are documented risk factors for recurrent UTIs. Estimates of baseline prevalence of BBD in children with UTI will help the clinician in the management strategy. Read More

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http://dx.doi.org/10.3389/fped.2020.00084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145391PMC

Minimally Invasive Treatment of Vesico-ureteral Reflux Using Endoscopic Injection of Polyacrylate-Polyalcohol Copolymer (Vantris) in Patients After Kidney Transplantation.

Transplant Proc 2020 Apr 13. Epub 2020 Apr 13.

Department of Urology, Medical University of Gdansk, Gdansk, Poland.

Background: Urinary tract infections (UTIs) are the most common infectious complications among kidney recipients. They occur due to the lack of an effective antireflux mechanism in the majority of techniques used during kidney transplantation. Subureteral injection of tissue bulking substance is a feasible alternative to open ureteral reimplantation. Read More

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http://dx.doi.org/10.1016/j.transproceed.2020.01.104DOI Listing

DNA copy number loss associated with pediatric urinary tract infection risk.

Innate Immun 2020 Apr 15:1753425920917193. Epub 2020 Apr 15.

Division of Epidemiology, Biostatistics and Environmental Health, School of Public Health, University of Memphis, USA.

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http://dx.doi.org/10.1177/1753425920917193DOI Listing

Urodynamic findings during the filling phase in neurogenic bladder patients with or without vesicoureteral reflux who have undergone sacral neuromodulation.

Neurourol Urodyn 2020 Apr 13. Epub 2020 Apr 13.

Department of Urology, China Rehabilitation Research Center, Beijing, China.

Aims: To assess the urodynamic findings during the filling phase in neurogenic bladder patients with or without vesicoureteral reflux (VUR) who underwent sacral neuromodulation (SNM).

Methods: We retrospectively reviewed the records of 19 patients with neurogenic lower urinary tract dysfunction (NLUTD) who underwent SNM at our center from July 2018 to July 2019. Clinical data and video-urodynamic parameters were collected. Read More

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http://dx.doi.org/10.1002/nau.24354DOI Listing
April 2020
2.873 Impact Factor

Ask-Upmark kidney in a girl with neurofibromatosis type 1.

CEN Case Rep 2020 Apr 10. Epub 2020 Apr 10.

Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan.

Ask-Upmark kidney (AUK) is a scarred segment of the kidney, characterized by formation of primitive tubular and glomerular structures, and sporadically diagnosed as a cause of hypertension (HTN). A 6-year-old girl with neurofibromatosis type 1 (NF1) and moyamoya syndrome had severe HTN. Based on past history, she had HTN at the age of 1. Read More

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http://dx.doi.org/10.1007/s13730-020-00470-0DOI Listing

Vesicoureteral reflux in patients diagnosed with pyeloureteral junction obstruction. Is screening justified?

Cir Pediatr 2020 Apr 1;33(2):71-74. Epub 2020 Apr 1.

Unidad de Gestión Clínica. Cirugía Pediátrica. Hospital Regional Universitario de Málaga. Málaga.

Introduction: The prevalence of vesicoureteral reflux (VUR) concomitant with pyeloureteral junction obstruction (PUJO) ranges from 5.2% to 18%. Today, there is no consensus on whether routine screening should be performed or not to rule out reflux, and it can be limited to selected patients. Read More

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Predicting Breakthrough Urinary Tract Infection: Comparative Analysis of Vesicoureteral Reflux Index, Grade and Ureteral Diameter Ratio.

J Urol 2020 Apr 3:101097JU0000000000001035. Epub 2020 Apr 3.

Emory University and Children's Healthcare of Atlanta, Atlanta, Georgia.

Purpose: Vesicoureteral Reflux Index (VURx) is a simple, validated tool for prediction of vesicoureteral reflux (VUR) resolution. Along with likelihood of spontaneous resolution, identification of children at risk for febrile urinary tract infection (fUTI) impacts management. We evaluated the utility of VURx as a predictive factor for breakthrough fUTI compared to VUR grade and distal ureteral diameter ratio (UDR). Read More

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http://dx.doi.org/10.1097/JU.0000000000001035DOI Listing

Guidelines for the medical management of pediatric vesicoureteral reflux.

Int J Urol 2020 Jun 1;27(6):480-490. Epub 2020 Apr 1.

Committee for the Formulation of Medical Management Guidelines for Pediatric Vesicoureteral Reflex, Japanese Society of Pediatric Urology, Osaka, Japan.

Urinary tract infection is a bacterial infection that commonly occurs in children. Vesicoureteral reflux is a major underlying precursor condition of urinary tract infection, and an important disorder in the field of pediatric urology. Vesicoureteral reflux is sometimes diagnosed postnatally in infants with fetal hydronephrosis diagnosed antenatally. Read More

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http://dx.doi.org/10.1111/iju.14223DOI Listing

mutation caused kidney hypoplasia and defective ureter-bladder connections in mice.

Int J Biol Sci 2020 12;16(9):1640-1647. Epub 2020 Mar 12.

Shanghai Kidney Development and Pediatric Kidney Disease Research Center, Children's Hospital of Fudan University, Shanghai 201102, China.

Limited genetic factors were uncovered for the development of congenital anomalies of the kidney and urinary tract (CAKUT). We previously reported that a Holliday junction resolvase was essential for early metanephric development in mice. This comprehensive follow-up study focused on the roles of in late metanephric development. Read More

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http://dx.doi.org/10.7150/ijbs.42855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097914PMC

Association of vesicoureteral reflux and gastroesophageal reflux disease in children: A population-based study.

Can Urol Assoc J 2020 Mar 30. Epub 2020 Mar 30.

Department of Urology, Dalhousie University, Halifax, NS, Canada.

Introduction: Practitioners have anecdotally hinted at a possible association between gastroesophageal reflux disease (GERD) and vesicoureteral reflux (VUR). We sought to identify an association in diagnosis between GERD and VUR using a population-based dataset in a well-defined geographic area covered by a single-payer healthcare system.

Methods: A retrospective review of individuals aged 0-16 years registered in the Nova Scotia Medical Service Insurance database from January 1997 to December 2012 was completed. Read More

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http://dx.doi.org/10.5489/cuaj.6308DOI Listing

Laparoscopic Extravesical Reimplantation in Children with Primary Obstructive Megaureter.

J Laparoendosc Adv Surg Tech A 2020 Mar 26. Epub 2020 Mar 26.

Department of Pediatric Surgery & Urology, University Hospital of Vall d'Hebron, Barcelona, Spain.

Conservative management of primary obstructive megaureter (POM) appears as the best option in patients with adequate ureteral drainage. Nevertheless, surgical intervention is indicated in cases of recurrent urinary tract Infections (UTIs), deterioration of split renal function, and significant obstruction. The gold standard includes: Ureteral reimplantation with or without tapering by open approach. Read More

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http://dx.doi.org/10.1089/lap.2019.0396DOI Listing

What urologists need to know about ketamine-induced uropathy: A systematic review.

Neurourol Urodyn 2020 Apr 25;39(4):1049-1062. Epub 2020 Mar 25.

Department of Urology, IRCCS INRCA, Ancona, Italy.

Aims: Ketamine is a general anesthetic. Dissociative effects and low cost led ketamine becoming an illegal recreational drug in young adults. Ketamine-induced uropathy (KIU) is one of the complications observed in abusers. Read More

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http://dx.doi.org/10.1002/nau.24341DOI Listing

Comparative Clinical Study Between Modified Ureteral Orthotopic Reimplantation and Cohen Method Under Pneumovesicum in Pediatric Patients With Hydroureteronephrosis.

Front Pediatr 2020 6;8:62. Epub 2020 Mar 6.

Department of Pediatric Surgery, Qilu Hospital, Shandong University, Jinan, China.

To report our initial experience with a modified ureteral orthotopic reimplantation technique under pneumovesicum and compare the outcomes vs. those obtained with the Cohen technique under pneumovesicum for the correction of primary obstructive megaureter (POM) or vesicoureteral reflux(VUR) in pediatric patients. A total of 46 patients (38 POM and 8 VUR; mean age: 16. Read More

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http://dx.doi.org/10.3389/fped.2020.00062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068794PMC

Robotic Ureteral Reimplantation.

J Endourol 2020 May 24;34(S1):S31-S34. Epub 2020 Mar 24.

Pediatric Urology, Children's Health Texas, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

Minimally invasive techniques have gained popularity in pediatric surgery. Among these, is the robotic approach for ureteral reimplantation in children with vesico-ureteral reflux. We describe main indications of this surgery, our surgical technique as well as trouble shooting of anatomical variants and the post-operative management. Read More

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http://dx.doi.org/10.1089/end.2019.0619DOI Listing

A Primer on Congenital Anomalies of the Kidneys and Urinary Tracts (CAKUT).

Clin J Am Soc Nephrol 2020 May 18;15(5):723-731. Epub 2020 Mar 18.

Department of Human Genetics, McGill University, Montreal, Quebec, Canada

Congenital anomalies of the kidneys and urinary tracts (CAKUT) are disorders caused by defects in the development of the kidneys and their outflow tracts. The formation of the kidneys begins at week 3 and nephrogenesis continues until week 36, therefore, the kidneys and outflow tracts are susceptible to environmental risk factors that perturb development throughout gestation. Many genes have been implicated in kidney and outflow tract development, and mutations have been identified in patients with CAKUT. Read More

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http://dx.doi.org/10.2215/CJN.12581019DOI Listing

Clinical Characteristics of Pediatric Pyelonephritis Without Pyuria or Bacteriuria.

Pediatr Infect Dis J 2020 May;39(5):385-388

From the Department of Pediatrics, National Hospital Organization, Kanazawa Medical Center.

Background: The gold standard for the diagnosis of acute pyelonephritis (APN) in children is the finding of both pyuria (P) and bacteriuria (B); however, some APN patients have neither of these findings [APN(P(-);B(-))].

Methods: In this study, we investigated APN patients who visited our hospital over 14 years to identify specific clinical characteristics of APN(P(-);B(-)).

Results: A total of 171 APN patients were included in the study, and of these 29 were APN(P(-);B(-)). Read More

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http://dx.doi.org/10.1097/INF.0000000000002609DOI Listing

An updated analysis of the surgical and urological complications of 789 living-related donor kidney transplantations: Experience of a single center.

Ulus Travma Acil Cerrahi Derg 2020 Mar;26(2):197-202

Department of Urology, İstanbul University İstanbul Faculty of Medicine, İstanbul-Turkey.

Background: This study aims to review retrospectively the surgical and urological complications encountered in 789 cases of living-related donor kidney transplantations (LRDKTs).

Methods: In this study, the clinical records of 789 LRDKTs, which were performed between 1983 and 2017, were reviewed retrospectively concerning surgical and urological complications.

Results: Overall, urological and surgical complications were encountered in 87 (11. Read More

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http://dx.doi.org/10.14744/tjtes.2019.78805DOI Listing
March 2020
0.379 Impact Factor

Accuracy of subjective vesicoureteral reflux timing assessment: supporting new voiding cystourethrogram guidelines.

Pediatr Radiol 2020 Mar 17. Epub 2020 Mar 17.

Division of Pediatric Urology, Department of Urology, Emory University School of Medicine, Children's Healthcare of Atlanta, 5730 Glenridge Dr., Suite 200, Atlanta, GA, 30328, USA.

Background: Bladder volume at the onset of vesicoureteral reflux (VUR) is an important prognostic indicator of spontaneous resolution and the risk of pyelonephritis.

Objective: We aim to determine whether pediatric urologists and pediatric radiologists can accurately estimate the timing of reflux by examining voiding cystourethrogram (VCUG) images without prior knowledge of the instilled contrast volume.

Materials And Methods: Total bladder volume and the volume at the time of reflux were collected from VCUG reports to determine the volume at the onset of VUR. Read More

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http://dx.doi.org/10.1007/s00247-020-04637-wDOI Listing

Emergence of as a Cause of Urinary Tract Infection: Results of the Routine Use of MALDI-TOF MS.

Microorganisms 2020 Mar 9;8(3). Epub 2020 Mar 9.

Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.

We analyzed the incidence and the clinical and laboratory characteristics of urinary tract infections (UTIs) during a 10-year period (2009-2018) and compared them with those of UTIs. A total of 38 and 162 episodes of and UTIs were observed. The number of UTIs was stable throughout the 10 years, whereas there was an obvious surge in the apparent number of UTIs since 2014, coinciding with the commencement of a routine use of MALDI-TOF MS. Read More

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http://dx.doi.org/10.3390/microorganisms8030381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7143294PMC

Myhre Syndrome Associated With Dunbar Syndrome and Urinary Tract Abnormalities: A Case Report.

Front Pediatr 2020 27;8:72. Epub 2020 Feb 27.

Department of Paediatrics, Medical School, Comenius University and National Institute of Children's Diseases, Bratislava, Slovakia.

Myhre syndrome is a rare condition caused by a mutation in the gene, which leads to a defective TGF-β/BMP signaling, resulting in the proliferation of abnormal fibrous tissues. Clinically, patients with Myhre syndrome manifest with defects of connective tissue (skin, muscles, joints), and cardiovascular and neurological impairment. In our report, we present a case of a 16-year-old female with skeletal abnormalities, reduced articular mobility, skin, and muscular hypertrophy and cardiovascular defects characteristic of Myhre syndrome. Read More

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http://dx.doi.org/10.3389/fped.2020.00072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057230PMC
February 2020

Associations of Plasma Neutrophil Gelatinase-associated Lipocalin, Anemia, and Renal Scarring in Children with Febrile Urinary Tract Infections.

J Korean Med Sci 2020 Mar 16;35(10):e65. Epub 2020 Mar 16.

Department of Pediatrics, Korea University Guro Hospital, Seoul, Korea.

Background: Neutrophil gelatinase-associated lipocalin (NGAL), a bacteriostatic agent, is known to inhibit erythropoiesis leading to anemia. We aimed to investigate the associations of NGAL, anemia, and renal scarring in children with febrile urinary tract infections (UTIs).

Methods: We retrospectively reviewed the medical records of 261 children with febrile UTIs. Read More

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http://dx.doi.org/10.3346/jkms.2020.35.e65DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073316PMC

Brazilian consensus on vesicoureteral reflux-recommendations for clinical practice.

Int Braz J Urol 2020 Jul-Aug;46(4):523-537

Universidade Federal da Bahia - UFBA, Salvador, BA, Brasil.

Introduction: Vesicoureteral Reflux (VUR) is characterized by a retrograde flow of urine from the bladder into the ureters and kidneys. It is one of the most common urinary tract anomalies and the major cause of urinary tract infection (UTI) in the first years of life. If not properly diagnosed and treated can lead to recurrent UTI, renal scar and, in severe cases, to end stage renal disease. Read More

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http://dx.doi.org/10.1590/S1677-5538.IBJU.2019.0401DOI Listing

Evolving surgical management of pediatric vesicoureteral reflux: is open ureteral reimplantation still the 'Gold Standard'?

Int Braz J Urol 2020 May-Jun;46(3):314-321

Department of Urology, Yale University School of Medicine, New Haven, CT 06520, USA.

Vesicoureteral reflux, the retrograde flow of urine from the bladder into the upper urinary tract, is one of the most common urologic diagnoses in the pediatric population. Once detected, therapeutic options for urinary reflux are diverse, ranging from observation with or without continuous low-dose prophylactic antibiotics to a variety of operative interventions. While a standardized algorithm is lacking, it is generally accepted that management be tailored to individual patients based on various factors including age, likelihood of spontaneous resolution, risk of subsequent urinary tract infections with renal parenchymal injury, and parental preference. Read More

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http://dx.doi.org/10.1590/S1677-5538.IBJU.2020.99.05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088498PMC
January 2020

Predictive factors for bacteremia in febrile infants with urinary tract infection.

Sci Rep 2020 Mar 11;10(1):4469. Epub 2020 Mar 11.

Department of Pediatrics, Yonsei University College of Medicine, Yonsei-ro 50, Seodaemun-gu, C.P.O. Box 8044, Seoul, 120-752, Korea.

This study aimed to investigate the predictive factors of concomitant bacteremia occurring in febrile infants who initially presented with pyuria and fever, and were subsequently diagnosed with culture-proven urinary tract infection (UTI). We conducted a retrospective cohort study for January 2010-October 2018 that included infants younger than six months with febrile UTI at a tertiary hospital. The study included 463 patients, of whom 34 had a concomitant bacteremic UTI. Read More

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http://dx.doi.org/10.1038/s41598-020-61421-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066144PMC
March 2020
5.078 Impact Factor

The Effectiveness of Sacral Neuromodulation on a Patient with a Previous Successful Cystoplasty Augmententation: a Case Report.

Urol J 2020 Feb 25. Epub 2020 Feb 25.

Urology and Nephrology Research Center, Shahid Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

This report is about the effectiveness of sacral neuromodulation in a 32-year-old woman with a history of augmented cystoplasty who required clean intermittent catheterization. She had referred to our center with a medical history of bilateral vesicoureteral reflux because of neuropathic lower urinary tract dysfunction. We successfully did a sacral neuromodulation on her which lead to a promising result. Read More

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http://dx.doi.org/10.22037/uj.v0i0.5439DOI Listing
February 2020

Urinary Tract Infection in Pediatric Patients on Clean Intermittent Catheterization via a Mitrofanoff port with Reused Catheters - Any Association with Catheter Sterility?

J Indian Assoc Pediatr Surg 2020 Mar-Apr;25(2):91-95. Epub 2020 Jan 28.

Department of Paediatric Surgery, PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu, India.

Objective: The objective of this study is to find out whether the reused catheters for clean intermittent catheterization (CIC) are colonized before insertion and its association with urinary tract infection (UTI).

Materials And Methods: This is a study conducted on 28 pediatric surgery patients who are on CIC via a Mitrofanoff port and who were reusing catheters, in a tertiary care private medical college hospital for 6-month period. Catheters to be used for the next catheterization were sent for culture along with urine culture. Read More

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http://dx.doi.org/10.4103/jiaps.JIAPS_10_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020673PMC
January 2020

Voiding Cystourethrogram in Children With Unilateral Multicystic Dysplastic Kidney: Is It Still necessary?

Urology 2020 May 18;139:156-160. Epub 2020 Feb 18.

Division of Pediatric Urology, Nicklaus Children's Hospital, Miami, FL; University of Miami Miller School of Medicine, Miami, FL; Division of Pediatric Urology, Joe DiMaggio Children's Hospital, Hollywood, FL. Electronic address:

Objective: To evaluate the value of the voiding cystourethrogram (VCUG) in children with multicystic dysplastic kidney (MCDK) who have a normal versus abnormal contralateral kidney and bladder ultrasound (US), and assess the risk of having vesicoureteral reflux (VUR) or urinary tract infection (UTI) based on the US results.

Methods: A retrospective chart review including children with unilateral MCDK with postnatal US and VCUG available at our institution between January 2008 and September 2017 was performed. Analysis was done to find association between abnormal contralateral US and contralateral VUR and UTI. Read More

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http://dx.doi.org/10.1016/j.urology.2020.02.005DOI Listing
May 2020
2.188 Impact Factor