4,985 results match your criteria Vesicoureteral Reflux
Prog Urol 2018 Dec 27;28(17):943-952. Epub 2018 Nov 27.
Service d'urologie, université Paris-7, hôpital Bichat Claude-Bernard, AP-HP, 46, rue Henri-Huchard, 75018 Paris, France.
Objective: The aim of this work was to issue clinical practice guidelines on antibiotic prophylaxis in urodynamics (urodynamic studies, UDS).
Materials And Methods: Clinical practice guidelines were provided using a formal consensus method. Guidelines proposals were drew up by a multidisciplinary experts group (pilot group = steering group), then rated by a panel of 12 experts (rating group) using a formal consensus method, and then peer reviewed by a reviewing/reading group of experts (different from the rating group). Read More
Med Arch 2018 Oct;72(4):272-275
Clinic for Nuclear Medicine, Clinical Center University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Introduction: The objective of this research was to determine whether vesicoureteral reflux(VUR) was associated with evolution to renal scarring (RS) following a febrile urinary tract infection (UTI) in infants.
Materials And Methods: Our research included 100 infants, ages up to 1 year with a first febrile UTI. The diagnostic was based on results of: laboratory findings, ultrasonography (USG), voiding cystourethrography (VCUG) and initial and control renal scintigraphy (DMSA renal scan) withtechnetiumTcsuccimer (dimercaptosuccinic acid), to assess the acute pyelonephritis (APN), VUR and RS. Read More
J Pediatr Urol 2018 Nov 12. Epub 2018 Nov 12.
The Hospital for Sick Children, Toronto, Canada. Electronic address:
J Pediatr Urol 2018 Nov 3. Epub 2018 Nov 3.
McMaster Pediatric Surgery Research Collaborative (MPSRC), McMaster University, Hamilton, Ontario, Canada; McMaster University/McMaster Children's Hospital, Department of Surgery, Division of Urology, Hamilton, Ontario, Canada. Electronic address:
Introduction: Multicystic dysplastic kidney (MCDK) is the most common type of renal cystic disease. It is associated with urinary tract abnormalities in the contralateral kidney in up to 30% of cases, most commonly vesicoureteral reflux (VUR).
Objectives: The objective of this study were to describe the incidence and selected issues in management and evolution for each VUR grade in the contralateral kidney of patients with unilateral MCDK to strengthen the scientific basis regarding the need for voiding cystourethrography (VCUG) screening. Read More
Acta Paediatr 2018 Nov 25. Epub 2018 Nov 25.
Department of Paediatrics and Nephrology, Children's Clinical Hospital of the Medical University of Bialystok, Bialystok, Poland.
Aim: The etiology of micturition disorders in children is multifactorial and still unclear. The perinatal factors may play a role in the development of children's urinary incontinence. We compared each type of micturition disorders in terms of length of gestation, birthweight, family history of bed-wetting and delivery type. Read More
J Pediatr Urol 2018 Oct 27. Epub 2018 Oct 27.
Department of Urology, Hacettepe University School of Medicine, Ankara, Turkey.
Introduction: Vesicoureteral reflux (VUR) is an anatomic or functional disorder, and it is a condition associated with renal scarring, hypertension, and end-stage renal disease. Renal damage can be prevented by appropriate medical and surgical intervention for selected patients.
Objectives: The objective of this study was to retrospectively analyze the surgically treated patient group of this study in reference to the risk analysis criteria used in European Association of Urology (EAU), European Society for Paediatric Urology (ESPU) guidelines to see the outcome of the study management protocol within the last 15 years in respect to this risk analysis. Read More
Pediatr Clin North Am 2019 Feb;66(1):1-13
Nephrology Section, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43205, USA; Department of Pediatrics, Ohio State University School of Medicine, 700 Children's Drive, Columbus, OH 43210, USA; Center for Clinical and Translational Research, The Research Institute at Nationwide Children's Hospital, 700 Children's Drive, W308, Columbus, OH 43205, USA. Electronic address:
Urinary tract infection (UTI) is the second most common bacterial infection in children and is considered a public health threat given the mounting rates of antibiotic-resistance among uropathogens. This article highlights recent encouraging developments in UTI research. Further work is necessary to translate the discoveries into accessible, cost-effective technologies that will aid clinicians in real-time decision-making. Read More
J Pediatr Urol 2018 Sep 25. Epub 2018 Sep 25.
Division of Urology, Department of Surgery, Sidra Medical and Research Center, Doha, Qatar. Electronic address:
Introduction: Penile ischemic injury is a reported catastrophic complication after complete primary repair of exstrophy (CPRE). Aiming to improve the bladder exstrophy-epispadias repair outcomes, the study institution adopted a modified staged exstrophy repair to incorporate the advantages of CPRE by avoiding concurrent epispadias repair and adding bilateral ureteral re-implantation and bladder neck tailoring (staged repair of bladder exstrophy with bilateral ureteral re-implantation [SRBE-BUR]) at the initial repair. It was hypothesized that such modifications minimize penile complications and prevent upper tract deterioration while enhancing bladder resistance and consequent capacity. Read More
J Pediatr Urol 2018 Oct 14. Epub 2018 Oct 14.
Boston Children's Hospital and Harvard Medical School, Boston MA United States. Electronic address:
In this episode of Mythbusters the premise that among infants with prenatally identified urinary tract dilation (UTD), voiding cystourethrogram (VCUG) should be performed in those with higher grade UTD but not in those with lower grade UTD is critically examined. It is concluded that severity of dilation is not strongly associated with risk of vesicoureteral reflux or other anomalies diagnosed by VCUG. Therefore, using hydronephrosis grade to decide which infants with UTD should undergo VCUG is not evidence based. Read More
Int J Surg Case Rep 2018 Oct 29;53:238-241. Epub 2018 Oct 29.
Urology Department, Hospital de Braga, Braga, Portugal; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal. Electronic address:
Introduction: Vesicoureteral reflux (VUR) corresponds to the reflux of urine from the bladder into the upper urinary system. It can be a congenital or an acquired anomaly and although its incidence is high in children it is uncommon in the adult life. One of its presentations in the adult population is the presence of recurrent Pyelonephritis. Read More
Adv Urol 2018 21;2018:4948165. Epub 2018 Oct 21.
Urology Resident in Kermanshah University of Medical Sciences, Kermanshah, Iran.
Introduction: Vesicoureteral reflux (VUR) is a common urologic anomaly in children. Many techniques have been offered to manage this condition, in which one of them is modified Gil-Vernet antireflux surgery. The study fullfiled to evaluate the efficacy and safety of modified Gil-Vernet antireflux surgery in correction of high-grade VUR. Read More
Can Urol Assoc J 2018 Nov 5. Epub 2018 Nov 5.
Department of Urology, Children's Hospital of Orange County, University of California, Irvine, CA, United States.
Introduction: Variability in the success rates for the endoscopic correction of vesicoureteral reflux (VUR) has prompted a debate regarding the use of routine postoperative voiding cystourethrogram (VCUG). This study examines the predictive performance of intraoperative mound morphology (IMM) and the presence of a postoperative ultrasound mound (PUM) on radiologic success, as well as investigates the role of using these two predictive factors as a composite tool to predict VUR resolution after endoscopic treatment.
Methods: This retrospective study included children with primary VUR who underwent endoscopic correction with a double HIT technique and dextranomer/hyaluronic acid copolymer. Read More
J Am Coll Radiol 2018 Nov;15(11S):S232-S239
Specialty Chair, University of Alabama at Birmingham, Birmingham, Alabama.
Pyelonephritis refers to infection involving the renal parenchyma and renal pelvis. In most patients, uncomplicated pyelonephritis is diagnosed clinically and responds quickly to appropriate antibiotic treatment. If treatment is delayed, the patient is immunocompromised, or for other reasons, microabscesses that form during the acute phase of pyelonephritis may coalesce, forming a renal abscess. Read More
Urology 2018 Oct 29. Epub 2018 Oct 29.
Pediatric Urology, University of California San Diego, Rady Children's Hospital, San Diego, CA.
Objective: To determine whether vesicoureteral reflux (VUR) that occurs during either the filling or voiding phase on voiding cystourethrogram (VCUG) has prognostic significance on successful endoscopic treatment.
Materials And Methods: A retrospective review was performed of 299 patients (438 ureters) with VUR who underwent endoscopic treatment with dextranomer/hyaluronic acid copolymer (Deflux) at a single institution from 2010 to 2013. Success was defined as absence of VUR on 3-month follow-up VCUG. Read More
Eur J Pediatr Surg 2018 Oct 31. Epub 2018 Oct 31.
Department of Pediatric Surgery, Ankara Children's Health and Diseases Hematology and Oncology Training and Research Hospital, Ankara, Turkey.
Introduction: Detecting renal scar is important in pediatric patients with vesicoureteral reflux (VUR) for deciding on treatment option. The aim of this study is to detect whether freehand elastosonography technique could be an alternative to dimercaptosuccinic acid (DMSA) scan in determining renal scar formation.
Materials And Methods: Between November 2015 and April 2016, 25 VUR patients, age ranging from 3 to 17 years admitted to our clinic, had urinary ultrasound and elastosonography, and data of approximately 147 renal region were recorded. Read More
Georgian Med News 2018 Sep(282):25-29
Kharkiv Medical Academy Of Postgraduate Education; Kharkiv National Medical University; Petro Mohyla Black Sea National University, Mykolaiv, Ukraine.
Nowadays, ureteroscopy is highly effective and minimally invasive therapeutic and diagnostic method which is not connected with the risk of complications and with correlation of intracorporal lithotripsy and it is optimal at ureterolithiasis. The aim of the research is to analyze the causes and the character of late postoperative complications which occur in patients with ureterolithiasis after ureterorenoscopy and contact lithotripsy using ultrasound lithitriptor. After ureterorenoscopy with contact lithotripsy or lithoextraction from 1372 patients in 96 (6,9%) cases further postoperative complications were detected: in 81 (84,4%) vesicoureteral reflux was detected, and in 15 (15,6%) - ureteric stricture. Read More
Neurourol Urodyn 2018 Oct 23. Epub 2018 Oct 23.
Department of Urology, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
Aims: To evaluate the accuracy of dynamic ultrasonography (DUS), as a feasible alternative diagnostic method to identify detrusor overactivity (DO) in patients with neurogenic bladder.
Methods: We performed concurrent analysis of 81 pairs of urodynamic study (UDS) and DUS, in 63 patients with myelomeningocele (MMC), from June 2014 to February 2017. The assessment focused on bladder behavior during the filling phase, DO evaluation, DO with leakage, compliance, and maximum cystometric capacity (MCC). Read More
Pediatr Int 2018 Oct;60(10):989-990
Department of Urology, Osaka Women's and Children's Hospital, Osaka, Japan.
Front Pediatr 2018 5;6:275. Epub 2018 Oct 5.
Pediatric Urology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
To assess long-term effectiveness, complications, and outcomes of primary obstructive megaureter (POM) treated by endoscopic balloon dilation (EBD) in the largest series reported. Hundred POM in 92 consecutive patients were treated by EBD between years 2004 and 2016. A total of 79 POM (73 patients) with more than 18 months of follow-up after treatment have been analyzed. Read More
J Pediatr Urol 2018 Sep 18. Epub 2018 Sep 18.
Department of Urology, University of California, San Francisco, USA. Electronic address:
Background: The association between obesity and urinary dysfunction in childhood has been described, albeit through retrospective analysis, making temporal relationships difficult to establish.
Objective: The objective of this study was to determine risk factors for significant weight gain in children at risk for recurrent urinary tract infections.
Study Design: A secondary analysis of the Randomized Intervention for Children with Vesicoureteral Reflux and Careful Urinary Tract Infection Evaluation trials was conducted. Read More
J Pediatr 2018 Oct 16. Epub 2018 Oct 16.
University of Pittsburgh School of Medicine, Pittsburgh, PA; Division of General Academic Pediatrics, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA. Electronic address:
Objectives: To identify factors associated with delayed antimicrobial treatment in febrile children with urinary tract infection (UTI).
Study Design: We reviewed data from 802 children with UTI enrolled in 2 previously conducted prospective studies (Randomized Intervention for Children with Vesicoureteral Reflux and Careful Urinary Tract Infection Evaluation) and extracted data on possible predictors of delayed treatment including age, sex, history of UTI, ethnicity, race, primary caregiver's education level, insurance, and income. We used univariate and multivariable analyses to investigate the relationship between these predictors and treatment delay. Read More
J Ultrason 2018 ;18(73):120-125
Department of Pediatric Radiology, Medical University of Lublin, Lublin, Poland.
Background: By now, two-dimensional contrast-enhanced voiding urosonography (ceVUS) has become a well-established method for the diagnosis and treatment monitoring of vesicoureteral reflux in children, particularly after the recent approval for this application in children in the USA and in Europe. The introduction of three-dimensional static (3D) and real-time (4D) techniques with ultrasound contrast agents opens up new diagnostic opportunities for this imaging modality.
Objective: To analyze whether 3D and 4D ceVUS is a superior technique compared to standard 2D ceVUS in diagnosing vesicoureteral reflux in children. Read More
Int Braz J Urol 2018 Nov-Dec;44(6):1194-1199
Department of Pediatric Surgery, Ege University Faculty of Medicine, Izmir, Turkey.
Introduction: Various bulking agents were utilized for endoscopic correction of VUR. A study reviewing multi-institutional data showed that the amount of injection material has increased over time with the purpose of improving success rates, which also resulted in costs. We noticed an opposite trend in our center since we started using a new bulking agent. Read More
Int Braz J Urol 2018 Nov-Dec;44(6):1207-1214
Pediatric Urology and Regenerative Medicine Research Center, Children's Medical Center, Pediatric Center of Excellence, Tehran University of Medical Sciences, Tehran, Iran.
Objective: To determine the different urine flow patterns and active pelvic floor electromyography (EMG) during voiding in children with vesicoureteral reflux (VUR) as well as presenting the prevalence of lower urinary tract symptoms in these patients.
Materials And Methods: We retrospectively reviewed the charts of children diagnosed with VUR after toilet training from Sep 2013 to Jan 2016. 225 anatomically and neurologically normal children were included. Read More
Int Braz J Urol 2018 Nov-Dec;44(6):1200-1206
Department of Pediatric Urology, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey.
Objective: To identify how many endoscopic injection (EI) procedures, STING method, must be performed before reaching an ideal success rate when simulation training has not been received.
Materials And Methods: The EI procedures performed by two pediatric urology fellows were investigated. The study excluded patients without primary VUR and those with previous EI or ureteroneocystostomy, lower urinary tract dysfunction, and/or duplicate ureters. Read More
Turk J Pediatr 2018 ;60(2):180-187
Division of Pediatric Surgery, Department of Pediatrics, Marmara University School of Medicine, İstanbul, Turkey.
Karadeniz-Cerit K, Thomas DT, Ergun R, Yıldız N, Alpay H, İnanır S, Dağlı ET, Tuğtepe H. Positional installation of contrast (PIC) and Redo-PIC cystography for diagnosis of occult vesicoureteral reflux. Turk J Pediatr 2018; 60: 180-187. Read More
Tunis Med 2018 Jan;96(1):42-47
Introduction: Acute pyelonephritis (APN) results from bacterial invasion of the renal parenchyma. The aim of this study was to investigate the epidemiological, clinico-biological, therapeutic and evolutionary APN and to identify the risk factors of this renal disease.
Methods: We conducted a retrospective and descriptive study, over a period of 37 years (1977-2014), including 43 patients with APN, hospitalized in our Department. Read More
Pediatr Transplant 2018 12 15;22(8):e13299. Epub 2018 Oct 15.
Division of Kidney Transplantation, Lucile Packard Children's Hospital, Stanford, California.
Purpose: The treatment of VUR in children with UTI has changed significantly, due to studies showing that antibiotic prophylaxis does not decrease renal scarring. As children with kidney transplants are at higher risk for UTI, we investigated if select patients with renal transplant VUR could be managed without surgery.
Materials And Methods: A total of 18 patients with VUR into their renal grafts were identified, and 319 patients underwent transplantation from 2006 to 2016. Read More
Urol J 2018 Oct 8. Epub 2018 Oct 8.
Department of Urology, University Medical Centre Maribor, Ljubljanska ulica 5, SI-2000 Maribor, Slovenia.
Purpose: To compare the efficacy of two bulking agents, Dextranomer-Hyaluronic Acid (DxHA) and Polyacrylate-Polyalcohol Copolymer (PPC) used for endoscopic treatment of vesicoureteral reflux (VUR).
Materials And Methods: We endoscopically treated 125 patients (89 girls and 36 boys) diagnosed with VUR grades I-V, comprising a total of 174 refluxing ureters (RUs). Patients were categorized into two groups, 99 (56,9%) RUs were treated with DxHA (Group 1) and 75 (43,1%) RUs with PPC (Group 2). Read More
BMJ Case Rep 2018 Oct 12;2018. Epub 2018 Oct 12.
Pediatric Critical Care, Inova Children's Hospital, Falls Church, Virginia, USA.
Posterior urethral valves (PUV) are an important cause of paediatric obstructive uropathy. PUV are usually diagnosed by prenatal ultrasonography (US) revealing hydronephrosis and bladder distention. We describe a 17-day-old male infant with abdominal distention who had no hydronephrosis on prenatal US. Read More
Urol Clin North Am 2018 Nov 7;45(4):641-657. Epub 2018 Sep 7.
Pediatric Urology, Division of Urology, Department of Surgery, Children's Hospital of Richmond, Virginia Commonwealth University School of Medicine, VCU Medical Center, PO Box 980118, Richmond, VA 23298-0118, USA. Electronic address:
Urinary tract dilatation (UTD) is the most common congenital anomaly detected on prenatal ultrasonography (US), affecting 1% to 3% of all pregnancies. This article focuses on the prenatal detection of UTD and the postnatal evaluation and management based on the UTD grading system risk assessment. Prophylactic antibiotics and postnatal imaging are discussed. Read More
Urol Clin North Am 2018 Nov 7;45(4):525-538. Epub 2018 Sep 7.
Department of Urology, University of Iowa, Carver College of Medicine, 200 Hawkins Drive, 3RCP, Iowa City, IA 5224, USA. Electronic address:
Continuous antibiotic prophylaxis (CAP) for urinary tract infection prevention in children with vesicoureteral reflux, hydronephrosis, and hydroureteronephrosis is reviewed. A more selective use of CAP is advocated based on a review of known individual risk factors in each of these conditions that subsequently helps identify the children most likely to benefit from CAP. Both short-term and potential long-term side effects of CAP are reviewed, including the impact of prophylactic antibiotics on bacterial resistance and the microbiome. Read More
Biomed Mater Eng 2018 ;29(6):821-837
School of Industrial and Information Engineering, Polytechnic University of Milan, Milan, Italy.
Two common abnormalities in ureters include primary refluxing megaureter (PRM) and primary obstructed megaureter (POM). The aim of this study was to represent the numerical simulation of the urine flow at the end of the ureter with vesicoureteral reflux (VUR) and POM during peristalsis. Methodologically, the peristalsis in the ureter wall was created using Gaussian distribution. Read More
Cir Pediatr 2018 Aug 3;31(3):146-152. Epub 2018 Aug 3.
Servicio de Pediatría. Complejo Hospitalario Universitario de Albacete.
Objectives: To assess the utility of a new modality of video-urodynamic for study of lower urinary tract dysfunction and other uropathies in kids, replacing voiding cystourethrography by echo-enhanced cystosonography, without ionizing radiations.
Material And Methods: Prospective study with simultaneous performance of filling cystometry and cystosonography in 43 kids during the last two years. The sonographic contrast was infused trough the urodynamic catheter. Read More
Pediatr Nephrol 2018 Sep 25. Epub 2018 Sep 25.
Division of Nephrology and Rheumatology, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, 157-8535, Japan.
Background: The purpose of this study was to resolve the clinical question as to whether all patients with unilateral multicystic dysplastic kidney (MCDK) should receive voiding cystourethrography (VCUG).
Methods: This is a retrospective study using cross-sectional analysis. Seventy-five children with unilateral MCDK were enrolled, excluding patients with other genetic or chromosome abnormalities, spinal cord diseases, or anal atresia. Read More
J Pediatr Urol 2018 Aug 27;14(4):319.e1-319.e7. Epub 2018 Jun 27.
Department of Urology, University of Texas Southwestern, Dallas, TX, USA.
Background: Baseline and interval dimercaptosuccinic acid (DMSA) scans and urodynamic (UD) studies are often obtained in infants and young children with spinal dysraphism (SD).
Objective: To identify practical UD parameters which accurately stratify urologic risk young children with SD.
Study Design: 130 expectantly managed infants/young children with SD and initial DMSA and UD before age 2 were reviewed. Read More
J Korean Med Sci 2018 Sep 8;33(38):e240. Epub 2018 Aug 8.
Department of Urology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Background: To report the long-term outcomes of endoscopic surgery (ES) in pediatric patients with vesicoureteral reflux in terms of success rate, urinary tract infection, and renal function.
Methods: We retrospectively reviewed the records of 73 pediatric patients (110 ureters) who underwent ES for vesicoureteral reflux. Ultrasonography was performed 1, 3, and 12 months postoperatively. Read More
Urology 2018 Nov 13;121:e1-e2. Epub 2018 Sep 13.
University of Miami, Miami Miller School of Medicine at Holy Cross Hospital, Fort Lauderdale, FL.
Ureter triplication is an extremely rare congenital anomaly of the urinary system with approximately 100 cases reported in medical literature, since it was first described in 1870. It is classified into 4 types, and commonly associated with ipsilateral or contralateral urological anomalies. In this report, we present a case of a pediatric Type III-triplicate ureter associated with ipsilateral vesicoureteral reflux and contralateral idiopathic renal atrophy that was discovered during kidney transplant work-up. Read More
J Urol 2018 Sep 12. Epub 2018 Sep 12.
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio. Electronic address:
Purpose: Robotic extravesical ureteral reimplantation has been established as a viable option for surgical management of vesicoureteral reflux. Typically, this procedure is associated with a hospital stay for routine postoperative care. The aim of the study was to assess the short-term safety of robotic unilateral extravesical ureteral reimplantation as a scheduled outpatient procedure in a pediatric population. Read More
Arch Esp Urol 2018 09;71(7):607-613
Endoscopy Department. Minimally Invasive Surgery Centre Jesús Usón. Cáceres. Spain.
Objectives: To assess the efficacy of a new anti-reflux intraureteral stent design in a swine model after minimally invasive treatment of ureteral stricture to reduce ureteral stent morbidity, previous to manufacture this design in a biodegradable fashion.
Methods: Twenty-eight female pigs were included. The study began with a cystoscopic, nephrosonographic and contrast fluoroscopic assessment. Read More
Pediatr Nephrol 2018 Sep 8. Epub 2018 Sep 8.
Pediatric Nephrourology Division, Department of Pediatrics, National Institute of Science and Technology (INCT) of Molecular Medicine, School of Medicine, Federal University of Minas Gerais (UFMG), R. Engenheiro Amaro Lanari 389/501, Belo Horizonte, MG, 30310-580, Brazil.
Background: Posterior urethral valves (PUVs) are associated with severe consequences to the urinary tract and are a common cause of chronic kidney disease (CKD). The aim of this study was to develop clinical predictive model of CKD in a cohort of patients with PUVs.
Methods: In this retrospective cohort study, 173 patients with PUVs were systematically followed up at a single tertiary unit. Read More
J Urol 2018 Sep 6. Epub 2018 Sep 6.
Division of Urology, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University, Chicago, IL, USA. Electronic address:
Purpose: Ureteral complications following renal transplantation are more common in children than in adults. We identify potential risk factors for ureteral complications in pediatric patients.
Materials And Methods: We performed a retrospective cohort study of patients who underwent renal transplantation at Lurie Children's Hospital between 2004 and 2016. Read More
J Nephrol 2018 Dec 6;31(6):863-879. Epub 2018 Sep 6.
Sant'Anna School of Advanced Studies, Department of Internal Medicine, University of Pisa, Pisa, Italy.
Chronic kidney disease (CKD) includes all clinical features and complications during the progression of various kidney conditions towards end-stage renal disease (ESRD). These conditions include immune and inflammatory disease such as: primary and hepatitis C virus (HCV)-related glomerulonephritis; infectious disease such as pyelonephritis with or without reflux and tuberculosis; vascular disease such as chronic ischemic nephropathy; hereditary and congenital disease such as polycystic disease and congenital cystic dysplasia; metabolic disease including diabetes and hyperuricemia; and systemic disease (collagen disease, vasculitis, myeloma). During the progression of CKD, ultrasound imaging and color Doppler imaging (US-CDI) can differentiate the etiology of the renal damage in only 50-70% of cases. Read More
Pediatr Dermatol 2018 Nov 6;35(6):e391-e392. Epub 2018 Sep 6.
Division of Dermatology, Department of Medicine, University of Arizona, Tucson, Arizona.
We present a special case of an 8-year-old girl diagnosed with severe drug reaction with eosinophilia and systemic symptoms due to trimethoprim-sulfamethoxazole for urinary tract infection prophylaxis for congenital vesicoureteral reflux. The patient is believed to have developed drug reaction with eosinophilia and systemic symptoms because of her underlying renal disease. Read More
J Res Med Sci 2018 23;23:76. Epub 2018 Aug 23.
Department of Medical Physics, Isfahan University of Medical Sciences, Isfahan, Iran.
Background: We assess the potency of different Doppler indices in the differentiation of obstructive and nonobstructive hydronephrosis.
Materials And Methods: In this study, infants and children who were referred for the evaluation of unilateral hydronephrosis were enrolled. Ultrasonography for the assessment of the degree of hydronephrosis and a voiding cystourethrogram for the exclusion of vesicoureteral reflux was performed. Read More
J Pediatr Urol 2018 Aug 23;14(4):325.e1-325.e7. Epub 2018 Jul 23.
Department of Urology and Pediatrics, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, 3RCP, Iowa City, IA, 52242-1089, USA. Electronic address:
Background: Continuous antibiotic prophylaxis (CAP) is a mainstay of treatment for children with vesicoureteral reflux (VUR). There has been an increasing focus on the effect of antibiotics on gut microbiota and subsequent repercussions on growth. Continuous antibiotic prophylaxis is generally considered safe; however, its impact on growth in children with VUR remains unknown. Read More
Urol J 2018 Aug 26. Epub 2018 Aug 26.
Department of Urology, Isfahan University of Medical Sciences (IUMS), Isfahan, Iran.
Purpose: In recent years, endoscopic subureteral injection has gained popularity as a therapeutic alternative to open surgery because of its high success rates and low morbidity. We compared the success and complication rates of Polyacrylate polyalcohol copolymer (PPC) and Dextranomer/Hyaluronic acid (Dx/HA) in the endoscopic treatment of VUR.
Materials & Methods: We retrospectively reviewed the patients who underwent endoscopic correction of their VUR by subureteric injection of PPC or Dx/HA from Jan 2010 to April 2016. Read More
Urol J 2018 Aug 26. Epub 2018 Aug 26.
Department of Urology,Faculty of Medicine, University of Çukurova, Adana, Turkey.
Introduction: The cytokine profile and the ultrastructural changes of refluxing ureterovesical junctions(UVJs) of children treated with failed dextranomer/hyaluronic-acid (Dx/HA) injections were investigated using immunohistochemical methods and transmission electron microscopy(TEM).
Patients And Methods: Eighteen children who underwent ureteroneocystostomy were included the study. The smooth muscle arrangement of the ureteral wall, transforming growth factor-?(TGF-?1),vascular-endothelial-growth factor(VEGF) and CD34 were evaluated immunohistochemically, and the results were compared with 10 age-matched autopsy specimens as controls. Read More
Int J Surg Case Rep 2018 19;51:150-153. Epub 2018 Aug 19.
Department of Urology, Tokyo Women's Medical University, Tokyo, Japan.
Introduction: Prune belly syndrome (PBS) presents with both renal dysplasia and urinary tract abnormalities. When performing kidney transplantation in PBS patients with kidney failure, extensive pretransplant urinary tract preparation may be necessary.
Presentation Of Case: We report the case of a 36-year-old man with PBS who underwent living-related kidney transplantation with urinary diversion using the Mitrofanoff principle. Read More