17 results match your criteria Vertebrobasilar Atherothrombotic Disease

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[Clinical features of ischaemic stroke with cerebral venous insufficiency and its risk factors.]

Adv Gerontol 2018;31(2):266-272

Saint-Petersburg State University, 7-9, Universitetskaya emb., St. Petersburg, 199034, Russian Federation;

Current research aimed to reveal clinical and neurological features of ischaemic stroke (IS) in patients suffering from cerebral venous insufficiency (CVI) combined with arterial hypertension (AH) and to identify its risk factors. Examination data of 112 patients with IS (aged 60-93 years old; mean age 72,1±2,6 years old, males - 39 (34,8%), females - 73 (65,2%), admitted at regional vascular center of St. Elizabeth City Hospital in Saint Petersburg, highlighted that cephalgic syndrome and vestibulocerebellar dysfunction occurred more frequently in stroke patients with CVI. Read More

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[Cerebral infarctions in vertebrobasilar artery atherosclerosis].

Arkh Patol 2018;80(1):3-10

Research Center of Neurology, Moscow, Russia.

Aim: to obtain more specific information on the morphology and pathogenesis of cerebral infarctions occurring in vertebrobasilar artery (VBA) atherosclerosis.

Material And Methods: Macro- and microscopic investigations of the brain, its arterial system, and heart were conducted in 69 autopsy cases with infarctions located in the vertebrobasilar system (VBS) in atherosclerosis.

Results: 69 cases were found to have 206 VBA infarctions of various extent and locations. Read More

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[Basilar artery occlusion--a diagnostic and therapeutic challenge].

Duodecim 2013 ;129(9):950-8

HYKS, neurologian klinikka, Meilahti ja Tutkimusohjelmayksikkö, molekyylineurologia ja neurotieteen osasto, kliininen laitos, Helsingin yliopisto.

Acute basilar artery occlusion is a neurological emergency that almost invariably leads to death or severe disability if not recanalized. Therapeutic recanalization is attempted using thrombolytic therapy either intravenously alone or by bridging it to on-demand, endovascular procedures. Due to often demanding differential diagnosis, angiographic evidence of basilar artery occlusion is necessary before treatment decisions. Read More

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Treatment of acute vertebrobasilar occlusion using thrombectomy with stent retrievers: initial experience with 18 patients.

AJNR Am J Neuroradiol 2013 May 1;34(5):1044-8. Epub 2012 Nov 1.

Department of Interventional Neuroradiology, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain.

Background And Purpose: Acute vertebrobasilar occlusion is an ominous disease with few proved effective treatments. Experience with stent retrievers is scarce and limited to combined therapies (stent retrievers associated with previous intravenous fibrinolysis, intra-arterial thrombolysis, or other mechanical devices). We present our experience with 18 patients treated with direct thrombectomy by using stent retrievers. Read More

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[Pathology of AtheroThrombosIS (ATIS)].

Makiko Ueda

Drugs 2010 Nov;70 Suppl 1:3-8

Department of Pathology, Osaka City University Graduate School of Medicine, Osaka, Japan.

Once atherosclerosis develops, stenosis (or occlusion) may occur in the lumen of various arteries of the living body. This can lead to a range of conditions, including myocardial infarction, cerebral infarction, aortic aneurysm and peripheral artery disease. The acronym 'ATIS' (AtheroThrombosIS) is a collective term for diseases characterized by a common course of development based on atherosclerosis. Read More

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November 2010

Ischemic stroke patterns and hemodynamic features in patients with small vertebrobasilar artery.

J Neurol Sci 2009 Dec 13;287(1-2):227-35. Epub 2009 Aug 13.

Department of Neurology, Myongji Hospital, Kwandong University College of Medicine, Goyang, Republic of Korea.

Background: To determine the role of small vertebrobasilar artery (SVBA) in patients with posterior circulation stroke (PCS), we evaluated the ischemic patterns, collateral features, and stroke mechanisms in PCS patients with SVBA.

Methods: Ischemic findings on magnetic resonance (MR) imaging were correlated with 3D time-of-flight/contrast-enhanced MR angiography and/or catheter angiography in 18 patients (mean age, 68.0+/-11. Read More

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December 2009

Vertebrobasilar ischemia and structural abnormalities of the vertebral arteries in active temporal arteritis and polymyalgia rheumatica--an ultrasonographic case-control study.

J Rheumatol 2005 Dec;32(12):2356-60

Department of Neurology, Klinikum Augsburg, Augsburg, Germany.

Objective: Temporal arteritis (TA) affects large arteries, including the vertebral arteries in up to 15% of cases. High resolution ultrasonography (US) is widely used for noninvasive imaging of the extracranial vertebral arteries. We assessed the prevalence of vertebrobasilar ischemia and structural abnormalities of the extracranial vertebral arteries by US in patients with TA and polymyalgia rheumatica (PMR) and in healthy controls. Read More

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December 2005

Acute vertebrobasilar occlusion: current treatment strategies.

Bernd Eckert

Neurol Res 2005 ;27 Suppl 1:S36-41

Allgemeines Krankenhaus Altona, Funktionsbereich Neuroradiologie, Hamburg, Germany.

Acute vertebrobasilar occlusion (VBO) remains a disease with a high mortality. Local intraarterial fibrinolysis (LIF) can reduce the mortality rate from about 90 to 60%. The combined therapy of i. Read More

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November 2005

Endovascular therapy of acute vertebrobasilar occlusion: early treatment onset as the most important factor.

Cerebrovasc Dis 2002 ;14(1):42-50

Department of Neuroradiology, University Hospital Hamburg-Eppendorf, Hamburg, Germany.

In view of the poor prognosis for patients with acute intracranial vertebrobasilar occlusion (VBO), factors were sought that predict survival and good neurologic outcome after acute endovascular treatment by means of local intra-arterial fibrinolysis (LIF) and percutaneous transluminal angioplasty (PTA). LIF was performed in 83 patients with angiographically established acute VBO. A significant residual stenosis after LIF was treated by additional PTA in 8 patients. Read More

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Acute basilar artery occlusion treated with combined intravenous Abciximab and intra-arterial tissue plasminogen activator: report of 3 cases.

Stroke 2002 May;33(5):1424-7

Department of Neuroradiology, University Hospital Hamburg-Eppendorf, Hamburg, Germany.

Background: Acute vertebrobasilar occlusion remains a disease with a high mortality even after treatment by local intra-arterial fibrinolysis. Adjunctive treatment with platelet glycoprotein IIb/IIIa receptor inhibitors such as abciximab may facilitate recanalization and improve the neurological outcome. Results after treatment of 3 patients by combined intravenous abciximab and local intra-arterial tissue plasminogen activator (tPA) are reported. Read More

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[Stroke of cardioembolic origin in Chagas disease].

Rev Neurol 2001 Aug 16-31;33(4):311-5

Servicio de Neurología; Hospital Sarah. Red Sarah de Hospitales del aparato Locomontor, Brasilia DF, 70330-901, Brasil.

Introduction: American trypanosomiasis, Chagas disease is caused by Trypanosoma cruzi. Between 10% and 30% of infected persons develop the chronic form, with predominance of the cardiac and gastrointestinal forms. Chagas myocardiopathy leads to congestive heart failure, dysrhythmias and thromboembolic phenomena, and may cause strokes. Read More

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January 2002

Posterior cerebral artery territory infarcts: clinical features, infarct topography, causes and outcome. Multicenter results and a review of the literature.

Cerebrovasc Dis 2000 May-Jun;10(3):170-82

Department of Neurology, University Hospital of Heidelberg, Germany.

Only a few large series of posterior cerebral artery (PCA) stroke exist, and clinical features and causes have not been studied as extensively as in other vascular territories. The PCA syndrome includes more clinical signs than the well-known visual field deficits. Concomitant findings are frequently sensory, slight motor and neuropsychological deficits. Read More

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Tissue plasminogen activator and plasminogen activator inhibitor in patients with acute ischemic stroke: relation to stroke etiology.

Neurol Res 1999 Dec;21(8):727-32

Department of Neurology, Kiel University Hospital, Germany.

Recent studies suggest that high plasma levels of tissue-type plasminogen activator (tPA) and its inhibitor (plasminogen activator inhibitor-1, PAI-1) are markers of an increased risk of atherothrombotic ischemic events such as stroke and myocardial infarction. In this prospective study, we measured tPA antigen, PAI-1 antigen and activity, as well as tPA/PAI-1 complex in patients with acute stroke. Stroke subtypes were classified according to the TOAST criteria. Read More

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December 1999

Endovascular stenting of an acutely thrombosed basilar artery: technical case report and review of the literature.

Neurosurgery 1999 Mar;44(3):667-73

Department of Radiology, University of California San Francisco Medical Center, 94143-0628, USA.

Objective And Importance: The goal of this report was to describe the successful percutaneous endovascular use of a Gianturco-Roubin-2 coronary stent in the treatment of an acute atherothrombotic occlusion of the basilar artery. To our knowledge, the percutaneous endovascular deployment of an intra-arterial stent for the treatment of an acute atherothrombotic occlusion of the basilar artery and the percutaneous endovascular placement of a Gianturco-Roubin-2 stent in the basilar artery have not been previously reported.

Clinical Presentation: An 83-year-old man presented with a recurrent, transient, locked-in syndrome resulting from a lower basilar artery occlusion caused by vertebrobasilar thrombosis superimposed on severe proximal basilar artery atheromatous stenosis. Read More

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Antithrombotic therapy of acute stroke: thrombolytic agents.

G J del Zoppo

Thromb Haemost 1997 Jul;78(1):183-90

Department of Molecular and Experimental Medicine, Scripps Research Institute, La Jolla, CA 92037, USA.

Following the initial report of the clinical use of plasminogen activators (PAs) in cerebrovascular thrombosis in 1958, interest in the efficacy of this approach accelerated only when the need for acute intervention in stroke was recognized. The use of PAs in acute ischemic stroke is based on the observation that approximately 80-90% of focal cerebral ischemic events presenting as strokes within 8 hr of symptom onset are due to atherothrombotic and embolic occlusions. Read More

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[Latency in the hospital admittance of stroke].

Rev Neurol 1995 Mar-Apr;23(120):272-5

Servicio de Neurología, Hospital de la Santa Creu i Sant Pau, Barcelona.

Objective: the hospital referral of 200 patients with cerebrovascular disorders in order to evaluate the possibility of treating acute cerebral infarction.

Method: by means of a personalized interview an evaluation was made of the time that had passed between the start of the symptomatology and the time the patient went into hospital. The results were then grouped into intervals and compared to the different nosological entities of cerebral vascular pathology. Read More

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January 1996

Prophylaxis and acute therapy of arterial embolism with special reference to cerebral embolism.

Herz 1991 Dec;16(6):444-55

Department of Neurology, University Hospital Mainz.

Prophylaxis and treatment of arterial embolism in high-risk patients includes therapy with antiplatelet drugs, anticoagulation, and vascular surgery. The prominent causes of cerebral ischemia are intraarterial emboli from atheromatous plaques and cardiac emboli. In patients with recent hemispheric transient ischemic attacks or minor stroke and ipsilateral high-grade internal carotid artery stenosis of 70 to 99% carotid endarterectomy has shown to be effective in prevention of major stroke or death. Read More

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December 1991
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