249 results match your criteria Verruciform Xanthoma

Case of cutaneous malakoplakia with verruciform xanthoma in the same lesion.

Clin Exp Dermatol 2022 Mar 31. Epub 2022 Mar 31.

Department of Dermatology, Dermatology Hospital, Southern Medical University, Guangzhou, China.

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Verruciform xanthoma associated with lichen planus.

Autops Case Rep 2022 21;12:e2021360. Epub 2022 Feb 21.

Universidade Federal do Rio Grande do Norte, Stomatology and Oral Pathology, Natal, RN, Brasil.

Verruciform xanthoma (VX) is a rare benign lesion of unknown etiology, with a rough or papillary aspect, painless, sessile, well-defined, most lesions do not exceed 2 cm in their largest diameter, the degree of keratinization of the surface influences color, varying white to red, affecting mainly the gingiva and alveolar mucosa, and can also be seen in skin and genital Herein, we present a report a clinical case of oral verruciform xanthoma in the buccal mucosa associated with the lichen planus lesion, as well as the morphological and immunohistochemical characteristics of the lesion. The clinical diagnostic hypothesis of oral lichen planus of the white reticular lesions on the buccal mucosa and on the tongue was confirmed by histopathology before a subepithelial connective tissue exhibiting intense inflammatory infiltrate in a predominantly lymphocytic band. In contrast, the hypothesis of the verrucous lesion in the left buccal mucosa was leukoplakia, with histopathological evidence showing exophytic and digitiform proliferations with parakeratin plugs between the papillary projections. Read More

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February 2022

Carcinoma cuniculatum in maxillary gingiva mimicking verruciform xanthoma: a case report.

Transl Cancer Res 2021 Oct;10(10):4553-4559

Department of Pathology, Qingdao Municipal Hospital, Qingdao, China.

Carcinoma cuniculatum (CC) is a rare and well-differentiated clinicopathological variant of squamous cell carcinoma (SCC) that is not common in head and neck. It is defined histologically by the infiltrative pattern of a deep, broad, and complex proliferation of stratified squamous epithelium with keratin cores and keratin-filled crypts. It has a propensity for local invasion and rare metastasis. Read More

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October 2021

Vulvar verruciform xanthoma mimicking genital warts: a case report.

Int J Dermatol 2021 Nov 30. Epub 2021 Nov 30.

School of Clinical Medicine, Jiangxi University of Chinese Medicine, Nanchang, China.

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November 2021

A case of verruciform xanthoma of the vulva with generalized verrucous nevus on extremities.

J Cosmet Dermatol 2021 Oct 10. Epub 2021 Oct 10.

Department of Dermatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.

Background: Verruciform xanthoma is a rare benign proliferative lesion of the skin and mucosa which mainly affects oral mucosa. Cases of verruciform xanthomas occurring outside the oral mucosa are rare. Verrucous nevus, also called epidermal nevus, is a cutaneous hamartoma caused by abnormal proliferation of epidermal keratinocytes. Read More

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October 2021

Verruciform Acral-Associated (Vacas) Xanthoma: Case Report and Review.

Cureus 2021 Jul 22;13(7):e16569. Epub 2021 Jul 22.

Dermatology, San Diego Family Dermatology, National City, USA.

Verrucous xanthoma is a benign histiocytic lesion of macrophage derivation. We describe a woman with a non-mucosal verruciform xanthoma located on her right thumb and review the features of patients with verruciform acral-associated xanthoma. A 69-year-old woman presented with a lesion on her right thumb of eight years duration that had been previously treated with liquid nitrogen cryotherapy without resolution. Read More

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Penile verruciform xanthoma mimicking large genital wart.

Int J Dermatol 2022 Feb 4;61(2):e43-e44. Epub 2021 Jul 4.

Department of Pathology, Ho Chi Minh City University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam.

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February 2022

A Case of Verruciform Xanthoma of the Sole.

Ann Dermatol 2021 Feb 30;33(1):86-88. Epub 2020 Dec 30.

Department of Dermatology, Hanyang University Guri Hospital, Guri, Korea.

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February 2021

Verruciform Xanthoma Occurring after Surgery for Genital Paget's Disease.

Indian Dermatol Online J 2021 Jan-Feb;12(1):174-175. Epub 2020 Sep 28.

Department of Dermatology, Fukushima Medical University, Fukushima, Japan.

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September 2020

Verruciform Xanthoma of the Ventral Surface of the Tongue: A Rare Case Report and Literature Review.

Iran J Otorhinolaryngol 2021 Jan;33(114):55-59

Dental Research Center, Research Institute of Dental Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Introduction: Verruciform xanthoma (VX) is an uncommon benign lesion with the subepithelial accumulation of foamy histiocytes and superficial papillary proliferations with a bright orange hue. This lesion exhibits an oral region predilection. Its clinical differential diagnosis includes verrucous leukoplakia, verrucous carcinoma, squamous papilloma, verruca vulgaris, condyloma accuminatum, squamous cell carcinoma, and fibroepithelial polyp. Read More

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January 2021

Subungual Verruciform Xanthoma.

Eckart Haneke

Dermatol Surg 2021 05;47(5):722-724

Dermatology Practice Dermaticum, Freiburg, Germany.

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[A vulvar verruciform xanthoma].

Ann Pathol 2022 Jan 19;42(1):85-88. Epub 2021 Jan 19.

Laboratoire d'anatomie pathologique, hôpital Cochin, Paris, France.

We report a case of a vulvar verruciform xanthoma. Verruciform xanthoma is a rare benign lesion that occurs most commonly on the oral and genital mucosa. Under the microscope, this lesion displays acanthotic papillary epidermis with parakeratosis that extends deep into the epithelium, elongated rete ridges and xanthomatous cells in the papillary dermis. Read More

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January 2022

Verruciform xanthoma: An elderly male genital predominance trend.

Australas J Dermatol 2021 May 28;62(2):e290-e292. Epub 2020 Nov 28.

Department of Dermatology, Chang Gung Memorial Hospital, Linkou, Taiwan.

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Giant extramucosal verruciform xanthoma over a discoid lupus erythematosus plaque in a patient with systemic lupus erythematosus.

Int J Dermatol 2020 Dec 20;59(12):e449-e450. Epub 2020 Oct 20.

Department of Dermatology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.

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December 2020

Oral verruciform xanthoma in chronic graft-versus-host disease patients.

Support Care Cancer 2021 Jan 15;29(1):79-84. Epub 2020 Aug 15.

Department of Oral Medicine, Sedation and Maxillofacial Imaging, Hebrew University-Hadassah School of Dental Medicine, Jerusalem, Israel.

Background: Verruciform xanthoma (VX) is an uncommon benign epithelial lesion which mainly appears in inflamed oral epithelium. In this study, our aim was to present new cases of oral VX (OVX) in chronic graft-versus-host disease (cGVHD) and review the literature.

Methods: We conducted a retrospective chart review of cGVHD patients (2012-2019) to reveal cases of OVX. Read More

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January 2021

Images of the month: Verruciform xanthoma: an easily confused disease.

Clin Med (Lond) 2020 07;20(4):e123-e124

The First Hospital of China Medical University, Shenyang, China

Verruciform xanthomas occur primarily in the mouth, but sometimes in the anogenital region, which may cause clinical confusion with genital warts. We present a case where a 70-year-old man presented with an asymptomatic warty lesion on the scrotum and verruciform xanthoma was confirmed by histopathological results. Read More

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Verruciform genital-associated xanthoma with acantholysis: Report of a rare case.

JAAD Case Rep 2020 Jul 21;6(7):658-660. Epub 2020 May 21.

Department of Pathology and Laboratory Medicine, Hartford Hospital, Hartford, Connecticut.

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An unusual association of porokeratotic eccrine ostial and dermal duct naevus with verruciform xanthoma.

Qiannan Jia Tao Qu

Australas J Dermatol 2020 Nov 1;61(4):e445-e446. Epub 2020 Jul 1.

Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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November 2020

Genital verruciform xanthoma: lessons from a contemporary multi-institutional series.

Histopathology 2020 Nov 15;77(5):841-846. Epub 2020 Sep 15.

Department of Pathology, VCU School of Medicine, Richmond, VA, USA.

Aims: Verruciform xanthoma (VX) is an uncommon lesion, seen in the oral mucosa and rarely occurring at cutaneous genital sites. Reports of exceptional VX presentations dominate the literature; herein, we assess the clinical and histological features of a cohort of routine, consecutive cases.

Methods And Results: Clinicopathological features of genital VXs from four academic centres were reviewed. Read More

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November 2020

Lower Urinary Tract Symptoms Due to Xanthoma of the Prostate After Kidney Transplantation: A Case Report.

Transplant Proc 2020 Nov 15;52(9):2736-2738. Epub 2020 May 15.

Departments of Anatomic Pathology and Urology, School of Medical Sciences, State University of Campinas (Unicamp), Campinas, Brazil.

Background: Prostatic xanthoma is a lesion of unknown cause that is often an incidental finding in patients undergoing needle biopsy or transurethral resection. To the best of our knowledge, we report on a unique case of a pure xanthoma without benign prostatic hyperplasia of the prostate in a patient with lower urinary tract symptoms manifested after kidney transplantation.

Methods: A 62-year-old man was submitted for a kidney transplant in April 2018. Read More

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November 2020

CD163 Foamy Macrophages Are Associated with the Morphogenesis of Oral Verruciform Xanthoma through Angiogenesis by VEGF Expression: An Immunohistochemical Study.

Dent J (Basel) 2020 Feb 14;8(1). Epub 2020 Feb 14.

Division of Pathology, Department of Pathology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.

Oral verruciform xanthoma (OVX) is an uncommon benign lesion that is characterized histologically by the accumulation of several foamy macrophages in the lamina propria papillae. The pathogenesis of OVX has not been completely elucidated, although the significance of macrophage polarization (M1, tumor suppression; and M2, tumor promotion) and the contribution of M2 macrophages to angiogenesis are well established. This study investigated the role of foamy macrophages in OVX, with a focus on angiogenesis. Read More

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February 2020

Oral Verruciform Xanthoma: A Series of 212 Cases and Review of the Literature.

Head Neck Pathol 2020 Sep 2;14(3):742-748. Epub 2020 Jan 2.

Department of Oral and Maxillofacial Diagnostic Sciences, University of Florida College of Dentistry, 1395 Center Drive, Gainesville, FL, 32610, USA.

Verruciform xanthoma (VX) of the oral cavity is an uncommon, reactive lesion of unknown etiology. In this study, we present a large series of VX with analysis of demographics, clinical appearance, histologic presentation and extensive review of literature. To the best of our knowledge, this is the largest series of oral VX reported to date. Read More

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September 2020

Verruciform xanthoma in a patient with recessive dystrophic epidermolysis bullosa: Case report and literature review.

Pediatr Dermatol 2020 Mar 26;37(2):355-357. Epub 2019 Dec 26.

Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

Verruciform xanthoma (VX) is a rare finding thought to be caused by epidermal damage from trauma or inflammation and has been reported in a limited number of patients with recessive dystrophic epidermolysis bullosa (RDEB). Herein, we describe a 20-year-old woman with RDEB who developed a large, verrucous, pink plaque on the posterior thigh that was histologically proven to be a VX. We review cases of VX in patients with RDEB and summarize the clinical features, pathophysiology, and management principles. Read More

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Verruciform xanthoma accompanying a cystic growth: A case report.

J Cutan Pathol 2020 May 23;47(5):475-478. Epub 2019 Dec 23.

Department of Dermatology, Japanese Red Cross Wakayama Medical Center, Wakayama, Japan.

Verruciform xanthoma, an uncommon, benign lesion with characteristic histopathological features, usually develops on the oral mucosa or genital area. We present an unusual case of verruciform xanthoma observed on the inguinal skin of a 52-year-old healthy man along with an underlying cystic component. The superficial lesion was a pedunculated nodule with a fissured surface and an 18-mm mound-like pigmented tumor underneath it. Read More

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Oral verruciform xanthoma associated with stem cell transplantation and graft versus host disease in a paediatric patient.

Bone Marrow Transplant 2020 09 10;55(9):1832-1833. Epub 2019 Dec 10.

Oral and Maxillofacial Surgery Department, Addenbrookes Hospital, Cambridge, Hills Road, Cambridge, CB2 0QQ, UK.

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September 2020

Verruciform xanthoma in recessive dystrophic epidermolysis bullosa and keratitis-ichthyosis-deafness syndrome: Report of two cases and a review of the literature.

Pediatr Dermatol 2020 Jan 11;37(1):176-179. Epub 2019 Nov 11.

Departments of Dermatology and Pediatrics, University of Massachusetts Medical School, Worcester, MA, USA.

Verruciform xanthoma is a benign, wart-like lesion that can clinically mimic squamous cell carcinoma. We describe two teenage patients with severe genodermatoses, recessive dystrophic epidermolysis bullosa (RDEB), and keratitis-ichthyosis-deafness (KID) syndrome, respectively, each found to have plaques suspicious for malignancy, later demonstrated on histopathologic examination to be verruciform xanthoma. We discuss the connection between these severe genodermatoses and the suspected pathophysiology of verruciform xanthoma. Read More

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January 2020

Verruciform Xanthoma of the Esophagus: Two Case Reports With Review of the Literature.

Int J Surg Pathol 2020 May 8;28(3):302-305. Epub 2019 Oct 8.

Kagoshima University, Graduate School of Medical and Dental Sciences, Kagoshima, Japan.

Verruciform xanthoma is a rare benign verrucopapillary lesion that develops in the oral mucosa and genital skin. Its development in the esophagus is extremely rare, with only 5 reported cases. We present 2 cases of verruciform xanthoma of the esophagus. Read More

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Tympanoxyloid verruciform xanthoma is a distinct feature of CHILD nevus.

J Eur Acad Dermatol Venereol 2020 Feb 8;34(2):e70-e72. Epub 2019 Oct 8.

Department of Dermatology, Medical Center - University of Freiburg, Freiburg im Breisgau, Germany.

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February 2020

Zebras in Foreskin Dermatopathology: A Review.

J Low Genit Tract Dis 2019 Jul;23(3):235-240

Department of Pathology, Immunology, University Hospital and Laboratory Medicine, Rutgers New Jersey Medical School, Newark, NJ.

Objectives: The aim of the study was to review uncommon foreskin dermatopathology conditions clinically and pathologically.

Methods: A database search of PubMed and Google Scholar were extracted between March 1, 2009, and March 1, 2019, using the search terms "foreskin," "prepuce," "penis," "pathology," "dermatology," and "rare." The search was limited to "humans" and "dermatopathology. Read More

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