334 results match your criteria Verruciform Xanthoma


Verruciform xanthoma overlying inflammatory linear verrucous epidermal nevus and in broad segmental distribution.

BMJ Case Rep 2018 Oct 17;2018. Epub 2018 Oct 17.

Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.

A 17-year-old woman presented with moderately itchy, non-progressive, linearly arranged verrucous plaques over dorsum of left foot since early childhood. Two years ago, she developed slowly increasing, verrucous exophytic growth in posterior most aspect of linear verrucous plaque. One year ago, she also developed multiple, linearly arranged, fleshy plaques with surface crusting over lateral aspect of right leg extending to thigh. Read More

View Article
October 2018

Inflammatory linear verrucous epidermal nevus responsive to 308-nm excimer laser treatment.

Cutis 2018 Aug;102(2):111-114

Advanced Dermatology Associates LTD; Lehigh Valley Health Network, Allentown, Pennsylvania, USA.

Inflammatory linear verrucous epidermal nevus (ILVEN) is a rare cutaneous disease that presents as linear psoriasiform plaques with associated prominent pruritus. The lesions commonly pre-sent on the legs with onset during childhood. Inflammatory linear verrucous epidermal nevus typically is refractory to treatment. Read More

View Article
August 2018
4 Reads

Verruciform Xanthoma with Equivocal Exfoliative Cytological Diagnosis.

Bull Tokyo Dent Coll 2018 ;59(3):193-200

Department of Oral and Maxillofacial Surgery, Tokyo Dental College.

Verruciform xanthoma (VX), a papillary or wart-like lesion of the mucosa, is histopathologically characterized by papillary projection of the epithelium and an aggregation of foam cells in the lamina propria. Here, we describe a case of VX in the posterior mandibular gingiva, initially suspected to be a benign lesion based on clinical findings and cytology prior to an excisional biopsy. The patient was a 62-year-old man who had visited a local dentist approximately 1 year earlier, presenting with a white lesion in the left posterior mandibular gingiva that resisted removal by scraping. Read More

View Article
January 2018

Verruciform and Condyloma-like Squamous Proliferations in the Anogenital Region.

Authors:
May P Chan

Arch Pathol Lab Med 2018 Sep 11. Epub 2018 Sep 11.

From the Department of Pathology, University of Michigan Health System, Ann Arbor.

Context: - Histologic distinction between condyloma acuminatum and various benign and malignant condyloma-like lesions in the anogenital area poses a common diagnostic challenge to pathologists across subspecialties.

Objective: - To review the overlapping and distinguishing features of condyloma acuminatum and its mimics, and to clarify confusing terminology and diagnostic criteria for problematic entities.

Data Sources: - A review of the literature on condyloma acuminatum (ordinary and giant types), verrucous carcinoma, warty/warty-basaloid high-grade squamous intraepithelial lesion and squamous cell carcinoma, papillary squamous cell carcinoma, bowenoid papulosis, verruca vulgaris, epidermolytic acanthoma, and verruciform xanthoma was performed. Read More

View Article
September 2018
5 Reads

Verruciform xanthoma of the penis: A rare case with an unusual clinical morphology.

Indian J Dermatol Venereol Leprol 2018 Sep-Oct;84(5):600-602

Department of Pathology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey.

View Article
August 2018
6 Reads

Oral verruciform xanthoma: Report of 13 new cases and review of the literature.

Med Oral Patol Oral Cir Bucal 2018 Jul 1;23(4):e429-e435. Epub 2018 Jul 1.

Department of Oral Medicine and Oral Pathology, School of Dentistry, National and Kapodistrian University of Athens, Greece, 2 Thivon Str, 11527, Goudi, Athens, Greece,

Background: Oral verruciform xanthoma (OVX) is a rare lesion. The purpose of the present study is to describe the clinical features of 13 OVXs and review all cases reported in the English literature.

Material And Methods: Thirteen cases of OVX diagnosed during a 47-year period were retrospectively collected. Read More

View Article
July 2018
1 Read

Oral Verruciform Xanthoma within Lichen Planus: A Case Report and Literature Review.

Case Rep Dent 2018 22;2018:1615086. Epub 2018 Apr 22.

Department of Oral Medicine and Pathology, School of Dentistry, National and Kapodistrian University of Athens, Athens, Greece.

Background: Verruciform xanthoma is an uncommon benign tumor, which exhibits a wide range of clinical patterns. The occurrence of the lesion in patients with immune-mediated mucocutaneous diseases may suggest a role of localized epithelial cell damage and chronic inflammation in its pathogenesis.

Case Report: A case of verruciform xanthoma on the tongue of a 56-year-old female with oral lichen planus is reported. Read More

View Article
April 2018
2 Reads

Dome-shaped nodules and scaly, verruciform plaques on the legs and feet.

Indian J Dermatol Venereol Leprol 2018 Apr 4. Epub 2018 Apr 4.

Department of Dermatology, Reina Sofía University Hospital, Córdoba, Spain.

View Article
April 2018
1 Read

CHILD syndrome mimicking verrucous nevus in a Chinese patient responded well to the topical therapy of compound of simvastatin and cholesterol.

J Eur Acad Dermatol Venereol 2018 Jul 1;32(7):1209-1213. Epub 2018 Feb 1.

Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Background: Congenital hemidysplasia with ichthyosiform erythroderma and limb defects (CHILD) syndrome is a rare X-linked dominant disorder characterized by peculiar cutaneous presentations and ipsilateral skeletal abnormalities. CHILD syndrome is caused by mutations in NSDHL gene, which involves in cholesterol synthesis.

Objectives: To verify the diagnosis of CHILD syndrome and seek effective pathogenesis-based therapy with little side-effects. Read More

View Article
July 2018
2 Reads

Verruciform xanthoma of the thumb.

Authors:
Zhiyu Li Yihua Wang

Indian J Dermatol Venereol Leprol 2018 Jan-Feb;84(1):67-69

Department of Pathology, Gulou Affiliated Hospital to Medical College of Nanjing University, Nanjing 210008, People's Republic of China.

View Article
November 2018
4 Reads

Oral verruciform xanthoma and erythroplakia associated with chronic graft-versus-host disease: a rare case report and review of the literature.

BMC Res Notes 2017 Nov 28;10(1):631. Epub 2017 Nov 28.

Department of Surgical, Oncological and Oral Sciences, University of Palermo, Via del Vespro 129, 90127, Palermo, Italy.

Background: Oral verruciform xanthoma is an uncommon benign lesion. Although oral verruciform xanthoma occurs in healthy individuals, it has been also reported in association with some inflammatory conditions. The aim of this study is to report a case of oral verruciform xanthoma associated with chronic graft-versus-host disease and to review the literature on this topic. Read More

View Article
November 2017
9 Reads

Ultramorphological and molecular characteristics of the larval stages of the horse nasal-myiasis fly, Rhinoestrus sp. (Diptera: Oestridae) from Mongolian horse in China.

Microsc Res Tech 2018 Feb 8;81(2):198-206. Epub 2017 Nov 8.

College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China.

Rhinoestrus sp. (Diptera: Oestridae) is an economically important parasite that can cause severe nasal myiasis in equids and can also affect humans. The ultrastructure of all Rhinoestrus sp. Read More

View Article
February 2018
2 Reads

Verruciform Xanthoma of a Lower Lip Lesion: A New Case and Review of the Literature.

Case Rep Dermatol 2017 May-Aug;9(2):130-135. Epub 2017 Aug 17.

Department of Dermatology, Near East University Faculty of Medicine, Nicosia, Cyprus.

A non-smoking man in his seventh decade presented with a lesion he had had for about 5 years on the right external surface of the lip 1 mm from the vermilion border. On physical examination, a yellowish-coloured, non-tender, verrucous mass of 0.5 × 0. Read More

View Article
August 2017
12 Reads

Superficial epithelioma with sebaceous differentiation: a case report with literature review.

Acta Dermatovenerol Alp Pannonica Adriat 2017 09;26(3):63-66

Institute of Pathology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.

Superficial epithelioma with sebaceous differentiation is the original name for a rare benign tumor that lacks consensus in the literature, both in nomenclature and in diagnostic criteria. We report the case of a 68-year-old male with a white papule on the left lower eyelid, fully excised. On histology, the lesion was a superficial, lobulated, plate-like epithelial proliferation, with small mature clusters of sebocytes and ductal structures. Read More

View Article
September 2017
3 Reads

Verruciform xanthoma of the tongue.

Natl J Maxillofac Surg 2017 Jan-Jun;8(1):78-80

Department of Oral and Maxillofacial Surgery, Bharati Vidyapeeth Deemed University Dental College and Hospital, Sangli, Maharashtra, India.

Verruciform xanthoma is a benign, soft tissue lesion occurring on the orogenital mucosa. Presentation of oral lesions can be pink, yellow, or gray raised plaque or papule with granular, papillary, or verrucous in nature. There are many theories proposed for the etiopathogenesis of verruciform xanthoma. Read More

View Article
August 2017
8 Reads

Mixed papillary-sarcomatoid carcinoma of the penis: report of an aggressive subtype.

Virchows Arch 2017 Dec 8;471(6):815-818. Epub 2017 Jul 8.

Department of Pathology, A. C. Camargo Cancer Center, São Paulo, Brazil.

Several different histological subtypes of penile carcinoma had been described in the last decades, many with different biological behavior and prognosis. The association of two histological subtypes (mixed tumors) can be observed in one third of the cases. The most common association is of warty and basaloid tumors, two HPV-related carcinomas. Read More

View Article
December 2017
7 Reads

A Case of Verruciform Xanthoma Arising in the Tongue.

J Clin Diagn Res 2016 Dec 1;10(12):ZD07-ZD08. Epub 2016 Dec 1.

Professor, Department of Oral and Maxillofacial Surgery, Wakayama Medical University , Wakayama, Wakayama Prefecture, Japan .

Verruciform Xanthoma (VX) is a rare lesion of the oral cavity. Histologically, it is characterized by papillary or verrucous proliferation of squamous epithelium and numerous foam cells. VX arising in the tongue is comparatively rare, as most cases of VX in oral cavity occur in gingiva. Read More

View Article
December 2016
4 Reads

[The alpha-herpesviridae in dermatology : Varicella zoster virus. German version].

Hautarzt 2017 Mar;68(3):187-191

Department of Dermatology, CHU of Sart Tilman, University of Liège, 4000, Liège, Belgien.

The second part of this publication deals with varicella zoster virus (VZV) and presents an overview of new, rare, and atypical clinical manifestations, including photolocalized varicella, hemorrhagic bullae during varicella, the implication of VZV in immunoglobulin A vasculitis, VZV-related alopecia, ulcerative varicella skin lesions, childhood herpes zoster (HZ), prolonged prodromal pains, recurrent HZ, VZV implication in burning mouth syndrome, verruciform VZV lesions, the significance of satellite lesions during HZ, and late HZ complications, either neurological or internal. Furthermore, certain associations between the occurrence of HZ and subsequent internal pathologies, as well as risk factors for HZ and new developments in vaccination against HZ will be addressed. Read More

View Article

The alpha-herpesviridae in dermatology : Varicella zoster virus.

Hautarzt 2017 Dec;68(Suppl 1):6-10

Department of Dermatology, CHU of Sart Tilman, University of Liège, 4000, Liège, Belgium.

The second part of this publication deals with varicella zoster virus (VZV) and presents an overview of new, rare, and atypical clinical manifestations, including photolocalized varicella, hemorrhagic bullae during varicella, the implication of VZV in immunoglobulin A vasculitis, VZV-related alopecia, ulcerative varicella skin lesions, childhood herpes zoster (HZ), prolonged prodromal pains, recurrent HZ, VZV implication in burning mouth syndrome, verruciform VZV lesions, the significance of satellite lesions during HZ, and late HZ complications, either neurological or internal. Furthermore, certain associations between the occurrence of HZ and subsequent internal pathologies, as well as risk factors for HZ and new developments in vaccination against HZ will be addressed. Read More

View Article
December 2017

Warty Carcinoma Penis: An Uncommon Variant.

Case Rep Pathol 2017 5;2017:2937592. Epub 2017 Jan 5.

Department of Pathology, Manipal College of Medical Sciences, Pokhara, Nepal.

Penile carcinoma frequency varies widely in different parts of the world and comprises 1-10% of all the malignancies in males. Majority of the cases of penile carcinoma are squamous cell carcinoma of penis comprising 60% to 70% of all cases. Warty carcinoma of penis is an unusual neoplasm and a variant of penile squamous cell carcinoma comprising 5%-10% of all the variants. Read More

View Article
January 2017
6 Reads

Wart on fire: A rare entity of verruciform xanthoma arising on a lower leg in a setting of chronic lymphedema.

JAAD Case Rep 2017 Jan 25;3(1):36-38. Epub 2017 Jan 25.

Division of Dermatology, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada.

View Article
January 2017
4 Reads

Verruciform xanthoma of the penis: A rare benign lesion that simulates carcinoma.

Arch Ital Urol Androl 2016 Dec 30;88(4):284-285. Epub 2016 Dec 30.

Department of Urology, IRCCS San Martino, University of Genova.

Verruciform xanthoma is a rare and benign condition predominantly affecting the oral cavity, but also skin and female anogenital mucosa. It can be flat, papular-warty or crateriform-cystic. Furthermore it can simulate HPV viral lesion such as condyloma and malignant neoplasia such as verrucous squamous cell carcinoma. Read More

View Article
December 2016
5 Reads

Verruciform xanthoma in the hard palate: a case report and literature review.

J Korean Assoc Oral Maxillofac Surg 2016 Dec 27;42(6):383-387. Epub 2016 Dec 27.

Department of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil.

Oral verruciform xanthoma (OVX) is an uncommon lesion that appears on the oral mucosa. The aim of this paper was to discuss the probable etiopathogenesis of OVX in the hard palate, reinforcing the importance of including this lesion in the differential diagnosis of verrucous lesions. A 43-year-old male smoker presented with a painless lesion with a verrucous surface and erythematous spots on the hard palate. Read More

View Article
December 2016
4 Reads

Giant vulvar verruciform xanthoma can mimic a common vulvar mass, genital warts.

Am J Obstet Gynecol 2017 04 25;216(4):422.e1-422.e2. Epub 2016 Nov 25.

Department of Obstetrics and Gynecology, Ewha Womans University, School of Medicine, Seoul, South Korea.

View Article
April 2017
3 Reads

Vegas (Verruciform Genital-Associated) Xanthoma: A Comprehensive Literature Review.

Dermatol Ther (Heidelb) 2017 Mar 15;7(1):65-79. Epub 2016 Nov 15.

Department of Dermatology, University of California San Diego, La Jolla, CA, USA.

Introduction: Verruciform xanthoma is a wart-like benign lesion. The classic histologic appearance consists of foamy histiocytes within elongated dermal papillae and epithelial acanthosis. The lesion most commonly occurs in the oral cavity, but has been reported in extra-oral sites such as the penis, scrotum, and vulva. Read More

View Article
March 2017
7 Reads

Differentiated exophytic vulvar intraepithelial lesions are genetically distinct from keratinizing squamous cell carcinomas and contain mutations in PIK3CA.

Mod Pathol 2017 03 11;30(3):448-458. Epub 2016 Nov 11.

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Human papillomavirus-negative keratinizing vulvar cancers typically harbor TP53 mutations as do their precursors, differentiated vulvar intraepithelial neoplasia. However, atypical verruciform proliferations are also associated with these malignancies and their pathogenesis is poorly understood. This study compared 11 atypical verruciform lesions, including atypical verruciform hyperplasia, vulvar acanthosis with altered differentiation, and verruciform lichen simplex chronicus, with 14 human papillomavirus-negative keratinizing squamous cell carcinomas. Read More

View Article
March 2017
24 Reads

Clinicopathological and Immunohistochemical Characteristics of Verruciform Xanthoma of the Lower Gingiva: A Case Report.

J Clin Diagn Res 2016 Jun 1;10(6):ZD05-6. Epub 2016 Jun 1.

Director, Department of Dentistry Oral and Maxillofacial Surgery, Ogaki Municipal Hospital , 4-86 Minaminokawa-cho, Ogaki, Gifu, Japan .

Verruciform xanthoma (VX) is a rare benign lesion and mainly effects the oral mucosa. This slow-growing asymptomatic lesion typically develops along the gingival margin of the masticatory mucosa, followed by the hard palate, tongue, buccal mucosa, floor of the mouth, alveolar mucosa, soft palate and junction between the hard and soft palate. Moreover, this lesion can also affect the skin and genital organs. Read More

View Article
June 2016
5 Reads

Vulvar verruciform xanthoma developing in acquired lymphangioma circumscriptum.

J Dermatol 2017 May 23;44(5):604-605. Epub 2016 Jun 23.

Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

View Article
May 2017
13 Reads

Verruciform xanthoma of the lip: A rarity.

Indian Dermatol Online J 2016 May-Jun;7(3):180-2

Department of Oral and Maxillofacial Pathology and Microbiology, DY Patil School of Dentistry, Navi Mumbai, Maharashtra, India.

Verruciform xanthoma (VX) is an uncommon, benign, asymptomatic mucocutaneous lesion of an unknown etiopathology. It usually presents as a papule or single plaque with a verrucous or a papillomatous surface and pale yellowish to red in color. It occurs primarily on the masticatory mucosa of middle-aged individuals. Read More

View Article
June 2016
4 Reads

Ackerman's Tumour - A Case Report.

J Clin Diagn Res 2016 Jan 1;10(1):ZD08-10. Epub 2016 Jan 1.

Senior Lecturer, Department of Oral Medicine and Radiology, Rajarajeswari Dental College and Hospital , Bangalore, Karnataka, India .

Ackerman's tumour or Verrucous Carcinoma (VC) is a distinct form of Squamous Cell Carcinoma (SCC). It is predominantly seen in elderly men and strongly associated with the use of tobacco. In oral cavity it occurs predominantly in buccal mucosa followed by gingiva, palate and floor of the mouth. Read More

View Article
January 2016
4 Reads

The wart on fire.

J Cutan Pathol 2016 Mar 12;43(3):293-4. Epub 2015 Oct 12.

Department of Dermatology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

View Article
March 2016
9 Reads

Verruciform Genital-Associated (Vegas) Xanthoma: report of a patient with verruciform xanthoma of the scrotum and literature review.

Dermatol Online J 2015 Aug 15;21(8). Epub 2015 Aug 15.

School of Allied Health Sciences, University of Nevada, Las Vegas.

Background: Verruciform xanthoma is a benign verrucous lesion characterized by epithelial acanthosis and lipid-laden foamy histiocytes in the connective tissue papillae. It typically presents as a papillomatous, polypoid, or sessile lesion. Verruciform xanthoma is most commonly observed within the oral cavity. Read More

View Article
August 2015
4 Reads

Unusual forms of cutaneous leishmaniasis due to Leishmania major.

J Eur Acad Dermatol Venereol 2016 Jul 7;30(7):1171-5. Epub 2015 Sep 7.

Center for Geographic Medicine and Tropical Diseases, Chaim Sheba Medical Center, Tel Hashomer, The Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Background: Cutaneous leishmaniasis (CL) due to Leishmania major (L. major) is common in the Middle East; however, this skin infection may be under-diagnosed when it presents atypically.

Objective: To highlight the occurrence of uncommon presentations of CL that may elude diagnosis. Read More

View Article
July 2016
3 Reads

Multiple verruciform xanthomas following bone marrow transplant.

Indian J Dermatol Venereol Leprol 2016 Mar-Apr;82(2):208-9

Department of Dermatology, Guangdong Provincial Dermatology Hospital, Guangzhou, Guangdong, China.

View Article
December 2016
4 Reads
1 PubMed Central Citation(source)
1.320 Impact Factor

Verruciform xanthoma developing in eroded skin of recessive dystrophic epidermolysis bullosa.

Eur J Dermatol 2015 Sep-Oct;25(5):509-10

Department of Dermatology, Graduate School of Medical Sciences,, Research and Clinical Center for Yusho and Dioxin, Kyushu University, 1-1 Maidashi 3-chome, Higashi-ku, Fukuoka 812-8582, Japan.

View Article
October 2016
5 Reads

Characteristic dermoscopic features of verruciform xanthoma: Report of three cases.

J Dermatol 2015 Nov 27;42(11):1103-4. Epub 2015 Jul 27.

Department of Dermatology, Saitama Medical University, Saitama, Japan.

View Article
November 2015
4 Reads

Clinicopathologic and outcome features of superficial high-grade and deep low-grade squamous cell carcinomas of the penis.

Authors:
Alcides Chaux

Springerplus 2015 9;4:248. Epub 2015 Jun 9.

Department of Scientific Research, Norte University, Gral. Santos e/25 de Mayo, Asunción, Paraguay ; Centro para el Desarrollo de la Investigación Científica, Asunción, Paraguay.

Purpose: To report the clinicopathologic and outcome features of superficial high-grade and deep low-grade penile squamous cell carcinomas.

Methods: From a retrospectively-collected series of patients with penile cancer we identified 41 cases corresponding to 12 superficial high-grade tumors and 29 deep low-grade tumors. As outcomes we evaluated inguinal lymph node status, presence of tumor relapse, final nodal status, and cancer-specific death. Read More

View Article
June 2015
3 Reads

Oral verruciform xanthoma: a clinicopathologic and immunohistochemical study of 20 cases.

J Cutan Pathol 2015 Jul 4;42(7):489-95. Epub 2015 Jun 4.

Oral Pathology, Department of Oral Diagnosis and Pathology, School of Dentistry, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.

Verruciform xanthoma of the oral cavity is an uncommon benign lesion that usually affects the palate and gingiva mainly as a well-circumscribed solitary yellowish to whitish plaque or nodule, which is promptly recognized microscopically by identification of sub-epithelial foamy macrophages. The aim of this study was to evaluate the clinicopathologic and immunohistochemical features of 20 cases of oral verruciform xanthoma. All cases were evaluated by conventional hematoxylin/eosin staining and six of those were submitted to immunohistochemical reactions for CD68, CD63, CD163, syndecan-1 (CD138), S-100 protein and cytokeratins (CK) 8, 14 and 19. Read More

View Article
July 2015
16 Reads

Congenital Plantar Angiofibroma-Like Hamartoma.

Pediatr Dermatol 2015 Jul-Aug;32(4):e167-8. Epub 2015 Apr 20.

Section of Dermatology, Medical College of Georgia, Georgia Regents University, Augusta, Georgia.

A 2-year-old girl presented with a congenital, slow-growing, exophytic nodule on the plantar surface of the foot. Histopathology revealed a hamartoma consisting of dermal angiofibroma features with overlying epidermal verruciform hyperplasia. Read More

View Article
May 2016
3 Reads

Oral verruciform xanthoma.

BMJ Case Rep 2015 Mar 27;2015. Epub 2015 Mar 27.

Department of Pathology, Bristol Dental Hospital, Bristol, UK.

Verruciform xanthoma (VX) of the oral cavity is a benign mucosal growth that often presents as a pink, yellow or grey raised plaque or papule with granular, papillary or verrucous surface morphology. Intraorally this often presents on the masticatory mucosa and extraorally often involves the skin and anogenital mucosa. There are several proposed aetiological factors and the clinical features of VX can be misleading; clinically it can resemble malignancy. Read More

View Article
March 2015
2 Reads

Verruciform xanthoma on the penis: an unusual location.

Clin Exp Dermatol 2015 Oct 18;40(7):807-8. Epub 2015 Mar 18.

Lauro de Souza Lima Institute, Bauru (SP), Brazil.

View Article
October 2015
3 Reads

[Costello syndrome. A rare RASopathy with cutaneous symptoms].

Authors:
M Wirtz J Frank

Hautarzt 2015 Apr;66(4):225-8

Hautklinik, Universitätsklinikum Düsseldorf, Düsseldorf, Deutschland.

An 18-year-old female with palmoplantar keratoderma, hyperhidrosis, facial verruciform papillomatosis, coarse face, growth retardation and developmental delay presented to our outpatient clinic. A diagnosis of Costello syndrome was made, and genetic counseling and a molecular genetic analysis were initiated. By this means, a heterozygous missense mutation in exon 2 of the HRAS gene, designated c. Read More

View Article
April 2015
1 Read

Oral verruciform xanthoma: a case report and literature review.

Case Rep Pathol 2014 8;2014:641015. Epub 2014 Dec 8.

Department of Diagnosis and Surgery, Paulista State University (UNESP), 1680 Humaitá Street, 14801-903 Araraquara, SP, Brazil.

Oral verruciform xanthoma represents an uncommon entity, which affects mainly oral mucosa. This paper presents the major clinical and histological features of oral verruciform xanthoma and reports a case on the tongue. The differential diagnosis and a literature review are also provided in light of recent information. Read More

View Article
December 2014
3 Reads
3 PubMed Central Citations(source)

Verruciform xanthoma: report of three patients with comparative dermoscopic study.

Clin Exp Dermatol 2015 Mar 5;40(2):156-9. Epub 2014 Dec 5.

Department of Dermatology, Teikyo University School of Medicine, Tokyo, Japan.

We report three cases of verruciform xanthoma (VX) in male patients aged 82, 88 and 39 years, respectively. The clinical appearance was of a mulberry-like area consisting of small papillae, which is typical of and specific to VX, and the diagnosis were histologically confirmed in all cases. Dermoscopy revealed that each surface papilla contained linear or hairpin vessels, which were surrounded by a marginal whitish rim. Read More

View Article
March 2015
3 Reads

A verruciform xanthoma of the lower lip and review of the differential diagnosis.

Oral Health Dent Manag 2014 Sep;13(3):712-6

Department of Oral Medicine and Radiology, Dr. Syamala Reddy Dental College, Hospital and Research Centre, Bangalore, India, e-mail:

A careful examination of lips is often neglected by the members of the medical and dental professions; yet the lips reveal a heterogeneous group of lesions ranging from congenital abnormalities to benign and malignant neoplasms. Verruciform Xanthoma (VX) is an uncommon benign inflammatory mucocutaneous condition that occurs in the oral cavity which was first described by Shafer in 1971. It is often associated with pre-existing epithelial and/or inflammatory disorder and is characterized histopathologically by papillary epithelial hyperplasia and the presence of foamy macrophages in connective tissue papillae. Read More

View Article
September 2014
3 Reads

What is your diagnosis? verruciform xanthoma.

Cutis 2014 Sep;94(3):115, 140-1

1113 Wyngate Dr, Greenville, NC 27834, USA.

View Article
September 2014
3 Reads

Verruciform xanthoma of oral cavity- a case report.

J Clin Diagn Res 2014 Jul 20;8(7):FD11-2. Epub 2014 Jul 20.

Senior Lecturer, Department of Oral Pathology & Microbiology, Dasmesh Institute of Research and Dental Sciences , Faridkot,India .

Verruciform xanthoma is an uncommon benign lesion of undetermined aetiology. It is a superficial normo-lipemic xanthoma, probably reflecting a multifactorial reactive and dystrophic process. Its clinical and pathological recognition and correct diagnosis is critical because it can occur in conjunction with other systemic and cutaneous inflammatory diseases; therefore, it necessitates further clinical assessment. Read More

View Article
July 2014
4 Reads

CHILD syndrome with mild skin lesions: histopathologic clues for the diagnosis.

J Cutan Pathol 2014 Oct 18;41(10):787-90. Epub 2014 Oct 18.

Department of Dermatology, University of Regensburg, Regensburg, Germany.

CHILD syndrome is an acronym signifying congenital hemidysplasia with ichthyosiform nevus and limb defects. A 27-year-old woman presented with chronic verrucous and hyperkeratotic skin lesions involving the left genital area, left hand and left foot since childhood. The histopathologic findings were consistent with verruciform xanthoma. Read More

View Article
October 2014
46 Reads

Disseminated verruciform xanthoma: a case report.

Cutis 2014 Jun;93(6):307-10

161 Ft Washington Ave, 12th Floor, New York, NY 10032, USA.

Verruciform xanthomas (VXs) are rare mucocutaneous lesions that can appear in isolation or in association with chronic inflammation, systemic diseases, or metabolic abnormalities. We report the case of a patient who presented with disseminated VX with oral, cutaneous, and genital involvement without an obvious underlying cause. Treatments including salicylic acid 40%, high-potency topical corticosteroids, antibiotics, and chlorhexidine failed to improve the lesions; however, the patient was satisfied with the cosmetic results of serial shave excisions. Read More

View Article
June 2014
7 Reads