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J Pak Med Assoc 2021 Apr;71(4):1260-1263

Department of Surgery, Shifa College of Medicine, Shifa Tameer E Millat University, Islamabad, Pakistan.

Mucinous cystadenoma is a rare tumour of the appendix. It accounts for only 0.4% of the gastrointestinal tract malignancies and is reported rarely in the literature. Read More

J Surg Case Rep 2021 Jun 10;2021(6):rjab204. Epub 2021 Jun 10.

Frimley Park Hospital, Camberley GU16 7UJ, UK.

Bleeding from the appendix is a rare cause of lower gastrointestinal haemorrhage. Previous publications have noted diagnosis via colonoscopy or computed tomography angiogram and treatment via surgical or endoscopy. We report a case of large volume per rectal bleeding from the appendix, with diagnosis and treatment via angiography and coil insertion, which is the first of its kind reported in the literature. Read More

J Clin Nurs 2021 Jun 13. Epub 2021 Jun 13.

Department of Industrial Engineering, Nineteen May University, Samsun, Turkey.

Aims And Objectives: To evaluate the effectiveness of cold application methods in reducing postpartum episiotomy pain.

Background: Many women suffer from pain after giving birth due to an episiotomy. This prolonged pain affects their daily lives as they recover. Read More

Acta Chir Belg 2021 Jun 12:1-15. Epub 2021 Jun 12.

Colorectal Unit, Department of Surgery, Flinders Medical Centre, Adelaide, Australia.

Background: After surgery for complicated appendicitis (CA), common practice is to treat all patients with a standardised long-course of intravenous antibiotics (IVAB) to reduce the risk of postoperative surgical infections (PSI). The aim of the current study was to evaluate the safety and efficacy of a short-course IVAB after CA in selected patients.

Methods: The Department's prospectively collected database identified CA patients treated between2015 and 2019. Read More

Sci Rep 2021 Jun 10;11(1):12303. Epub 2021 Jun 10.

Huntsman Cancer Institute, University of Utah, 2000 Circle of Hope, Salt Lake City, UT, 84112-5550, USA.

Neuroendocrine tumors (NETs) of the small intestine undergo large chromosomal and methylation changes. The objective of this study was to identify methylation differences in NETs and consider how the differentially methylated genes may impact patient survival. Genome-wide methylation and chromosomal copy number variation (CNV) of NETs from the small intestine and appendix were measured. Read More

Stud Hist Philos Sci 2021 Jun 27;87:54-71. Epub 2021 Mar 27.

Department of Philosophy, Boise State University, USA.

Environmental problems often outstrip the abilities of any single scientist to understand, much less address them. As a result, collaborations within, across, and beyond the environmental sciences are an increasingly important part of the environmental science landscape. Here, we explore an insufficiently recognized and particularly challenging barrier to collaborative environmental science: value pluralism, the presence of non-trivial differences in the values that collaborators bring to bear on project decisions. Read More

Int J Cardiovasc Imaging 2021 Jun 9. Epub 2021 Jun 9.

Cardiology Department, Mehmet Akif Ersoy Thoracic And Cardiovascular Surgery Training and Research Hospital, University Of Health Sciences Istanbul, Turgut Ozal Bulvarı no:11, 34303, Istanbul, Küçükçekmece, Turkey.

Mitral stenosis (MS) is tolerated for an extended period in patients with atrial septal defect (ASD) known as Lutembacher syndrome due to depressurizing effect. In a similar way, patients with patent foramen ovale (PFO) may have clinical benefits in severe MS. We aim to evaluate the clinical effects of PFO in rheumatic MS. Read More

Sci Rep 2021 Jun 9;11(1):12170. Epub 2021 Jun 9.

Department of Pediatric Hematology and Oncology, St. Anna Children's Hospital, Medical University of Vienna, Kinderspitalgasse 6, 1090, Vienna, Austria.

Acute appendicitis is a rare gastrointestinal complication of anti-cancer chemotherapy and hematopoietic stem cell transplantation. Among a cohort of 2341 hemato-oncologic patients at a pediatric tertiary care cancer center, we identified 21 patients (0.9%) with 23 episodes of acute appendicitis, based on pathological imaging of the appendix and clinical findings. Read More

Cancer Rep (Hoboken) 2021 Jun 8:e1462. Epub 2021 Jun 8.

Department of Gastrointestinal Surgery, Stavanger University Hospital, Stavanger, Norway.

Background: Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) comprise a heterogeneous disease group. Factors that affect long-term survival remain uncertain. Complete population-representative cohorts with long-term follow-up are scarce. Read More

Indian J Urol 2021 Apr-Jun;37(2):189-190. Epub 2021 Apr 1.

Department of Urology, VPS Lakeshore Hospital, Kochi, Kerala, India.

Patients with ureteral defects and salvageable renal units present a challenge in reconstructive urology. Vermiform appendix interposition is an option in the management of mid-ureteral defects that can not be managed by primary ureteroureterostomy. Laparoscopic appendicular interposition ureteroplasty is a technically demanding and an infrequently attempted procedure. Read More

Mol Psychiatry 2021 Jun 8. Epub 2021 Jun 8.

University Bordeaux, CNRS, ImmunoConcEpT, UMR 5164, Bordeaux, France.

Hippocampal adult neurogenesis has been associated to many cognitive, emotional, and behavioral functions and dysfunctions, and its status as a selected effect or an "appendix of the brain" has been debated. In this review, we propose to understand hippocampal neurogenesis as the process underlying the "Baldwin effect", a particular situation in evolution where fitness does not rely on the natural selection of genetic traits, but on "ontogenetic adaptation" to a changing environment. This supports the view that a strong distinction between developmental and adult hippocampal neurogenesis is made. Read More

Curr Med Imaging 2021 Jun 8. Epub 2021 Jun 8.

Department of Anatomic Pathology, Tokyo Medical University, Tokyo, Japan.

Background: Gastrointestinal schwannoma is not a common type of tumor, and lesions originating from the appendix are extremely rare. Herein, we report a patient with appendiceal schwannoma characterized by lymph node swelling.

Case Report: A 67-year-old male patient who had diabetes complained of weight loss. Read More

J Electromyogr Kinesiol 2021 May 27;59:102565. Epub 2021 May 27.

School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Australia. Electronic address:

Consensus on the definition of common terms in electromyography (EMG) research promotes consistency in the EMG literature and facilitates the integration of research across the field. This paper presents a matrix developed within the Consensus for Experimental Design in Electromyography (CEDE) project, providing definitions for terms used in the EMG literature. The definitions for physiological and technical terms that are common in EMG research are included in two tables, with key information on each definition provided in a comment section. Read More

ESMO Open 2021 Jun 4;6(3):100168. Epub 2021 Jun 4.

Department of Medicine I, Division of Oncology, Medical University of Vienna, Vienna, Austria. Electronic address:

Background: Brain metastases (BM) are a rare complication in colorectal cancer (CRC) patients and associated with an unfavorable survival prognosis. Primary tumor side (PTS) was shown to act as a prognostic and predictive biomarker in several trials including metastatic CRC (mCRC) patients. Here, we aim to investigate whether PTS is also associated with the outcome of CRC patients with BM. Read More

J Laparoendosc Adv Surg Tech A 2021 Jun 7. Epub 2021 Jun 7.

Department of General and Upper GI Surgery, Barnsley District General Hospital NHS Trust, South Yorkshire, United Kingdom.

Securing of the appendix stump is one of the key steps in performing laparoscopic appendicectomy (LA). This can be achieved by a variety of methods including endoloops, stapler, and clips. An alternative technique, previously described by authors, is the use of Johan forceps as a knot pusher, to deploy an extracorporeal Roeder knot at the base of appendix. Read More

Urol Case Rep 2021 Sep 19;38:101727. Epub 2021 May 19.

Urology Department, Academic Hospital Habib Bourguiba, Sfax, Tunisia.

Despite theadvancements in surgical reconstructive techniques for bladder exstrophy-epispadias complex, urinary incontinence represents a major problem that affects the quality of life. Bladder augmentation associated to Mitrofanoff external continent urinary diversion (ECUD) constitute for some surgeon the best solution for the management of bladder exstrophyallowing to achieve continence and to preserve renal function. Read More

Lancet 2021 Jun 3;397(10292):2331-2333. Epub 2021 Jun 3.

Francis Crick Institute, London, UK. Electronic address:

Lancet 2021 06;397(10290):2149

Research Institute Diabetes Academy Mergentheim, Bad Mergentheim, Germany; Department of Clinical Psychology and Psychotherapy, University of Bamberg, Bamberg, Germany.

Wiad Lek 2021 ;74(5):1277-1280

STATE ORGANIZATION «GRYGORIEV INSTITUTE FOR MEDICAL RADIOLOGY AND ONCOLOGY OF THE NATIONAL ACADEMY OF MEDICAL SCIENCES OF UKRAINE», KHARKIV, UKRAINE.

The authors have analyzed medical histories of two patients, treated in health care facilities of Kharkiv region from 2008 to 2020. These patients underwent urgent appendectomy, given the existing clinic of acute appendicitis. Morphological examination of the surgical material allowed us to diagnose adenocarcinoma in one case, and neuroendocrine tumor in combination with endometriosis in the other case. Read More

J Obstet Gynaecol Can 2021 Jun 2. Epub 2021 Jun 2.

Calgary, AB.

Objective: To provide an update on current recommendations for cytomegalovirus (CMV) infection during pregnancy. The objectives of this guideline are: To improve perinatal care providers' awareness of the consequences of maternal CMV infection for the fetus and the infant; To emphasize the importance of educating patients about how to prevent CMV acquisition during pregnancy To raise perinatal care providers' awareness of new developments in CMV screening and treatment To highlight that a substantial proportion of disability due to congenital CMV (cCMV) can be modified to some extent TARGET POPULATION: Patients of child-bearing age, pregnant patients, and patients planning a pregnancy.

Benefits, Harms, And Costs: The patient partners urged us to make awareness of preventive strategies a high priority, despite concern that discussing CMV with patients could cause unnecessary anxiety. Read More

J Obstet Gynaecol Can 2021 Jun 2. Epub 2021 Jun 2.

Calgary, AB.

Objective: To provide an update on current recommendations for cytomegalovirus (CMV) infection during pregnancy. The objectives of this guideline are: To improve perinatal care providers' awareness of the consequences of maternal CMV infection for the fetus and the infant; To emphasize the importance of educating patients about how to prevent CMV acquisition during pregnancy To raise perinatal care providers' awareness of new developments in CMV screening and treatment To highlight that a substantial proportion of disability due to congenital CMV (cCMV) can be modified to some extent Target Population: Patients of child-bearing age, pregnant patients, and patients planning a pregnancy.

Benefits, Harms, And Costs: The patient partners urged us to make awareness of preventive strategies a high priority, despite concern that discussing CMV with patients could cause unnecessary anxiety. Read More

Actas Urol Esp (Engl Ed) 2021 Jun 14;45(5):406-411. Epub 2021 May 14.

Department of Urology, Landesklinikum Korneuburg-Teaching Hospital, Korneuburg, Austria.

Introduction: The authors describe the technique of orthotopic bladder replacement with an ileocecal pouch and unaltered appendix used as an orthotopic urethral substitute. Additional procedures with regard to the bothersome voiding symptoms will be described.

Material And Methods: In a small cohort of 5 patients with muscle invasive bladder cancer with tumor involvement of the bladder neck or proximal urethra (2 males/3 females) we performed the following reconstruction. Read More

J Adv Pract Oncol 2021 Apr 1;12(3):315-318. Epub 2021 Apr 1.

Memorial Sloan Kettering Cancer Center, New York, New York.

During JADPRO Live Virtual 2020, Kristen O'Hagan, ANP-BC, MS, AOCNP®, provided an overview of rare gastrointestinal tumors, their presentation, and current treatment algorithms. Ms. O'Hagan also discussed the advanced practitioner's role in managing these diseases. Read More

BMJ Case Rep 2021 Jun 2;14(6). Epub 2021 Jun 2.

Radiology, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India

A 52-year-old woman was referred to our department with multiple discharging sinuses and swelling in the right flank and iliac region for the past year. Ultrasound revealed a large collection in the right psoas muscle with the sinus tract reaching up to the skin in the right iliac region. Despite repeated attempts at drainage, the collection continued to increase in size. Read More

J Surg Res 2021 May 30;266:345-351. Epub 2021 May 30.

Surgical Outcomes Quality Improvement Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611; Division of Pediatric Surgery, Department of Surgery, Northwestern University Feinberg School of Medicine, Ann & Robert H. Lurie Children's Hospital, Chicago, Illinois 60611. Electronic address:

Background: This study sought to evaluate the influence of International Classification of Diseases, Tenth Revision (ICD-10) transition on Perforated Appendix Admission Rate (PAAR), which is a commonly used indicator representing access to care developed by Agency for Healthcare Research and Quality (AHRQ).

Materials And Methods: In this interrupted time series study of Pediatric Health Information System database from 2013 to 2018, we employed three study phases (pre-implementation, washout, and initial implementation) to evaluate the influence of ICD-10 transition on trends in PAAR. ICD-10 diagnosis codes suggested by AHRQ's specifications were used to identify perforated and simple appendicitis, and PAAR was estimated accordingly. Read More

BMC Pediatr 2021 06 1;21(1):258. Epub 2021 Jun 1.

Department of Pediatrics, Medical College of Wisconsin, Children's Corporate Center Suite 560, 999 North 92nd Street, Wisconsin, 53226, Milwaukee, USA.

Background: Abdominal pain and other gastrointestinal symptoms are common presenting features of multisystem inflammatory syndrome in children (MIS-C) and can overlap with infectious or inflammatory abdominal conditions, making accurate diagnosis challenging.

Case Presentation: We describe the case of a 16-year-old female who presented with clinical symptoms suggestive of appendicitis and an abdominal computed tomography (CT) that revealed features concerning for appendicitis. After laparoscopic appendectomy, histopathology of the appendix demonstrated only mild serosal inflammation and was not consistent with acute appendicitis. Read More

Materials (Basel) 2021 May 27;14(11). Epub 2021 May 27.

Department of Architecture and Industrial Design, University of Campania Luigi Vanvitelli, Abbazia di San Lorenzo ad Septimum, Via S. Lorenzo, 81031 Aversa, Italy.

In the initial article, the data in the Appendix A Section, Table A6, were incorrect [... Read More

Cancers (Basel) 2021 May 19;13(10). Epub 2021 May 19.

Comprehensive Cancer Center, Department of General, Visceral and Transplant Surgery, University of Tübingen, 72076 Tübingen, Germany.

(1) : Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy provide survival benefits to selected patients. We aimed to report our experience and the evolution of our peritoneal surface malignancy program. (2) : From June 2005 to June 2017, 399 patients who underwent cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy at the Tübingen University Hospital were analyzed from a prospectively collected database. Read More

Materials (Basel) 2021 May 7;14(9). Epub 2021 May 7.

Joining and Welding Research Institute, Osaka University, Osaka 567-0047, Japan.

The authors wish to revise the following from pages 16-18 in the text of Appendix B [... Read More

BMC Surg 2021 May 31;21(1):272. Epub 2021 May 31.

Department of Oncosurgery, Faculty of Medicine, Commenius University Bratislava, Spitalska 24, Bratislava, 813 72, Slovakia.

Background: Closure of the appendix stump presents the most critical part of laparoscopic appendectomy. The aim of the present study was to compare the medical outcomes and cost analysis of laparoscopic appendectomy with respect to the different methods of stump closure.

Methods: This was a prospective randomized clinical trial conducted in a single institution (University Hospital Ostrava) within a 2-year study period. Read More