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Environ Geochem Health 2019 Apr 22. Epub 2019 Apr 22.

Department of Chemistry, Centre for Advanced Studies, Guru Nanak Dev University, Amritsar, Punjab, 143001, India.

The assessment of heavy metal contents in environmental sectors is important to estimate the carcinogenic and non-carcinogenic doses and risks for the mankind associated with it. The present work deals with the assessment of the risk exposure related to heavy metal contents in groundwater and soil samples to two different age groups via three different transits, i.e. Read More

Asian-Australas J Anim Sci 2019 Apr 15. Epub 2019 Apr 15.

College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, China.

Objective: Lactobacilli in rabbit intestine is rare and its function on rabbit gut health is not fully understood. The present study aimed to evaluate in vivo the probiotic potential of Lactobacillus casei for suckling rabbits.

Methods: Two healthy 5-day-old suckling rabbits with similar weights from each of 12 New Zealand White litters were selected and disturbed to control group and treatment group. Read More

Medicine (Baltimore) 2019 Apr;98(16):e15333

Oncology Department, WangJing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.

Rationale: Small-cell lung cancer (SCLC) is a common pathological type of lung cancer, but appendiceal metastasis of SCLC was rare. At present, clinical studies on the maintenance therapy of SCLC have not reached a significant conclusion.

Patient Concerns: We reported on a 52-year-old man who diagnosed as extensive stage SCLC with abdominal pain for 2 months, aggravated for 2 days. Read More

Genes (Basel) 2019 Apr 18;10(4). Epub 2019 Apr 18.

Laboratório de Genética Pesqueira e Conservação (GenPesC), Instituto do Mar, Universidade Federal de São Paulo (UNIFESP), Santos 11070-102, Brazil.

Today, elasmobranchs are one the most threatened vertebrate groups worldwide. In fact, at least 90% of elasmobranch species are listed in the International Union for Conservation of Nature (IUCN) Red List, while more than 40% are data-deficient. Although these vertebrates are mainly affected by unsustainable fishery activities, bycatch is also one of the major threats to sharks and batoids worldwide, and represents a challenge for both sustainable fishery management and for biodiversity and conservational efforts. Read More

Int J Surg Case Rep 2019 Apr 5;58:37-40. Epub 2019 Apr 5.

Radiological Department, Klatovy Hospital, Plzeňská 929, 339 01, Klatovy II, Czech Republic.

Introduction: Shortly after an operation infection, intraabdominal abscess, seroma, haemorrhage or development of paralytic ileus may occur. Postoperative adhesions, nonspecific abdominal pain without signs of obstruction, incisional hernia and appendicitis or mucocele in appendiceal stump present common late complications. We present a unique case of a late complication after appendectomy. Read More

PLoS One 2019 19;14(4):e0215406. Epub 2019 Apr 19.

College of Ocean and Earth Sciences, Xiamen University, Xiamen, China.

The peppermint shrimp Lysmata vittata (Caridea: Hippolytidae) is a marine caridean shrimp popular in marine aquarium trade. The species is known to display the sexual system of protandric simultaneous hermaphrodite. In this study, based on captive bred specimens, the complete ontogenetic gonad development of L. Read More

Lancet Glob Health 2019 May;7(5):e613-e623

Population Health Research Institute, Department of Medicine, McMaster University and Hamilton Health Sciences, Hamilton, ON, Canada.

Background: The associations between the extent of forced expiratory volume in 1 s (FEV) impairment and mortality, incident cardiovascular disease, and respiratory hospitalisations are unclear, and how these associations might vary across populations is unknown.

Methods: In this international, community-based cohort study, we prospectively enrolled adults aged 35-70 years who had no intention of moving residences for 4 years from rural and urban communities across 17 countries. A portable spirometer was used to assess FEV. Read More

Int J Surg Case Rep 2019 Apr 9;58:21-25. Epub 2019 Apr 9.

Deprtment of General Surgery, JSS Medical College and Hospital, Mysore, India. Electronic address:

Introduction: Appendiceal mucocele is a rare disease and has a clinical picture that resembles acute appendicitis. A correct diagnosis before surgery is very important for the selection of surgical technique(appendicectomy/colectomy)to avoid severe intraoperative and postoperative complications. The work has been reported in line with the SCARE criteria (Agha et al. Read More

Clin Case Rep 2019 Apr 14;7(4):806-808. Epub 2019 Mar 14.

Department of Surgery Wexford General Hospital Wexford Ireland.

We describe the different clinical presentations, radiology, histology and management of this unique, highly aggressive disease. Clinical presentation of appendicitis may not just be appendicitis. Appendiceal tumors must always be considered in the differential diagnosis. Read More

J Surg Case Rep 2019 Apr 10;2019(4):rjz106. Epub 2019 Apr 10.

PGY4 Resident General Surgery at PUCE, Quito-Ecuador.

Bowel perforation due to inadvertent ingestion of foreign objects is, fortunately, a rare event. However, it can lead to deadly complications when it occurs. Thin, sharp and pointed objects like toothpicks are more likely to pierce the bowel wall. Read More

J Am Soc Mass Spectrom 2019 Apr 16. Epub 2019 Apr 16.

Department of Mechanical Engineering, IUPUI, 723 W Michigan st, Indianapolis, IN, 46202, USA.

The strong synergy arising from coupling two orthogonal analytical techniques such as ion mobility and mass spectrometry can be used to separate complex mixtures and determine structural information of analytes in the gas phase. A tandem study is performed using two systems with different gases and pressures to ascertain gas-phase conformations of homopolymer ions. Aside from spherical and stretched configurations, intermediate configurations formed by a multiply charged globule and a "bead-on-a-string" appendix are confirmed for polyethylene-glycol (PEG), polycaprolactone (PCL), and polydimethylsiloxane (PDMS). Read More

J Infect Chemother 2019 Apr 11. Epub 2019 Apr 11.

Department of Bacteriology, Nagoya City University Graduate School of Medical Sciences, Japan.

Purpose: Controversy exists over whether bacterial flora within the appendix differs between patients with and without appendicitis. To examine these potential differences, we cultured the appendiceal luminal microbiota of patients with and without acute appendicitis, and identified the bacterial species therein.

Methods: Fifty-seven patients with acute appendicitis and 37 patients without acute appendicitis who underwent curative resection of colorectal cancer and prophylactic appendectomies (control group) were included. Read More

Updates Surg 2019 Apr 13. Epub 2019 Apr 13.

Department of Visceral and Thoracic Surgery, Cantonal Hospital Winterthur, Brauerstrasse 15, 8401, Winterthur, Switzerland.

More than 10,000 appendectomies are performed every year in Switzerland. The aim of this study was to investigate the treatment strategy for appendicitis among Swiss surgeons with particular interest in laparoscopic technique, method of appendiceal stump closure, and abdominal lavage. We performed an anonymous survey among 540 members of the Swiss Surgical Society. Read More

Int J Surg Case Rep 2019 Apr 5;57:201-204. Epub 2019 Apr 5.

University of Duhok, College of Medicine, Department of Surgery, Duhok city, Kurdistan Region, Iraq.

Introduction: Ingestion of foreign bodies and their impaction at the lumen of the appendix is a very rare finding and only few cases have been reported all over the world. A variety of metallic foreign bodies when ingested may be lodged in the lumen of the appendix such as screws, bird shots, and needles. This is called in most literatures as foreign body appendicitis. Read More

Radiol Case Rep 2019 Jun 29;14(6):704-707. Epub 2019 Mar 29.

Rashid Hospital, Dubai, UAE.

De Garengeot's hernia is a rare entity defined as the presence of the appendix within the femoral hernia sac. Although appendicitis is a common surgical emergency, appendix herniation into the groin results in a complex symptoms and signs, which make it difficult to diagnose clinically. We report a case of a 72-year-old male who had De Garengeot's hernia. Read More

Radiologia 2019 Apr 8. Epub 2019 Apr 8.

Departamento de Radiología, Hospital Universitari Vall d'Hebron, Barcelona, España.

Objective: To review the embryology, the clinical findings and the appearance in multidetector computed tomography (MDCT) of complicated Meckel's diverticulum (DM) in adults.

Conclusion: The presence of an MD in a MDCT should be suspected when a blind tubular structure connected to the terminal ileum by a neck of variable size is observed. Multiplanar 2D reconstructions images and CT enterography can help in the diagnosis. Read More

AJR Am J Roentgenol 2019 Apr 11:1-6. Epub 2019 Apr 11.

1 Toronto Joint Department of Medical Imaging, University Health Network-Mount Sinai Hospital-Women's College Hospital, University of Toronto, 585 University Ave, 1PMB-283, Toronto, ON M5G 2N2, Canada.

Objective: The purpose of this study was to determine whether a novel morphologic characteristic of appendiceal mucoceles at CT-focal distal appendiceal dilatation with a segment of morphologically normal appendix proximally-could predict an underlying neoplastic pathologic abnormality before surgery and histopathologic assessment.

Materials And Methods: A retrospective study was performed that assessed CT cases from 2012 through 2014. Cases showing morphologic features of a mucocele were identified and categorized into two subgroups: focal distal dilatation with a segment of normal appendix proximally and generalized appendiceal dilatation. Read More

AJR Am J Roentgenol 2019 Apr 11:1-9. Epub 2019 Apr 11.

1 Department of Radiology, Saitama Children's Medical Center, Japan.

Objective: The purpose of this study is to evaluate the association between sonographic findings and the operative time of transumbilical laparoscopic-assisted appendectomy (TULAA) for appendicitis in children.

Materials And Methods: We included 131 children who underwent ultrasound within 24 hours before TULAA. We evaluated the associations between operative time and patients' demographics, as well as the following sonographic findings: maximum outer wall diameter of the appendix, appendicolith, ascites (not echogenic), echogenic ascites, abscess formation, increased intraabdominal fat echo in the right lower quadrant (RLQ; 3-point scale), and the location of the appendix (three locations). Read More

Clin J Gastroenterol 2019 Apr 10. Epub 2019 Apr 10.

Department B of Surgery, Charles Nicolle Hospital, Tunis, Tunisia.

Retaining the etiology of a cystic lesion in the right iliac fossa can be difficult. Appendicular hydatid cyst is a very uncommon cause of a such lesion. In some cases, diagnosis is not obvious. Read More

Chem Asian J 2019 Apr 9. Epub 2019 Apr 9.

Harbin Institute of Technology (Shenzhen), School of Materials Science and Engineering, G907, HIT campus, Xili university Town, 518055, Shenzhen, CHINA.

The research progress of colloidal motors, synthetic colloids that convert environmental energy and swim in water, has attracted much attention in recent years. Yet, its rapid development and interdisciplinary nature has created a hurdle for beginners, especially students and postdocs. In light of this challenge, this tutorial review gives a bird's eye overview of the research field of colloidal motors, presenting in a beginner-friendly manner subjects including the definition and significance of colloidal motors, physical challenges associated with their motion at the microscale, their fabrication and propulsion mechanisms, functionalities that enable their applications, and essential tools and techniques useful for beginners. Read More

Cureus 2019 Jan 29;11(1):e3980. Epub 2019 Jan 29.

Internal Medicine, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, USA.

Low-grade appendiceal mucinous neoplasm (LAMN) is a rare malignancy with symptoms varying depending on the clinical manifestations. The most worrisome complication of this particular neoplasm is seeding of mucin into the adjacent peritoneum leading to pseudomyxoma peritonei (PMP). There is a lack of standardized treatment approach; however, an appendectomy-only approach is currently being used for the resection of non-metastatic disease. Read More

Surg Case Rep 2019 Apr 8;5(1):55. Epub 2019 Apr 8.

Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki city, Nagasaki, 852-8501, Japan.

Background: Schistosomiasis is prevalent in tropical and subtropical areas and rarely reported in developed countries. Schistosomiasis often occurs as a chronic illness, which can cause liver and intestinal damage. Appendicitis is an unusual complication of schistosomiasis. Read More

Int J Syst Evol Microbiol 2019 Apr 5. Epub 2019 Apr 5.

3​Department of Biology, University of Konstanz, D-78457 Constance, Germany.

Part A of Appendix 9 - Orthography of the International Code of Nomenclature of Prokaryotes regulates the formation of compound generic names and specific epithets derived by combining two or more words or word elements of Latin and/or Greek origin, using the word stems and connecting vowels (-o- or -i-) following word elements derived from Greek and Latin, respectively. The rules given and the exceptions listed are suitable for substantives (nouns) and adjectives used as word elements, but not for prepositions and prefixes. Therefore, we propose a non-retroactive modification of Appendix 9 so that the guidelines given in Part A apply only to compound names that include a noun or an adjective in a non-final position. Read More

Abdom Radiol (NY) 2019 Apr 4. Epub 2019 Apr 4.

Department of Radiology and Biomedical Imaging, University of California San Francisco, 505 Parnassus Avenue, Box 0628, San Francisco, CA, 94131, USA.

Purpose: The objectives of this study was to assess the performance of ultrasound (US) for suspected appendicitis in adult patients and to evaluated the additive value of short-interval (within 1 week) computed tomography (CT) or Magnetic Resonance Imaging (MRI) after performing an initial US.

Methods: In this IRB-approved, HIPAA-compliant, retrospective study, electronic medical records (EMRs) were queried for "US appendicitis" performed over a 2-year interval. EMR was reviewed for CT or MRI performed within 1 week of this exam, and if any new or additional information was available at subsequent exam. Read More

J Surg Case Rep 2019 Mar 29;2019(3):rjz086. Epub 2019 Mar 29.

Department of General Surgery, University Hospital Center of Oporto, Oporto, Portugal.

Incidental appendiceal neuroendocrine tumors (ANETs) occur in 0.2-0.7% of surgical resections for suspected appendicitis (Moris, Tsilimigras, Vagios, Ntanasis-stathopoulos, Karachaliou, Papalampros, Neuroendocrine neoplasms of the appendix: a review of the literature. Read More

Gastroenterol Hepatol Bed Bench 2019 ;12(1):74-75

Ankara Numune Training and Research Hospital, Department of Internal Medicine, Ankara, Turkey.

Chronic diarrhea is defined as diarrhea that lasts longer than four weeks. Etiology of chronic diarrhea includes inflammatory bowel disease, malabsorption syndromes, irritable bowel disease, chronic parasitic infections, bacterial toxins, drugs and motility disorders. Plastron appendicitis is an abscess formation that occurs when the appendix is surrounded by the omentum following perforation of acute appendicitis. Read More

Evid Based Complement Alternat Med 2019 3;2019:3961395. Epub 2019 Mar 3.

Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.

Background: Traditional Chinese Medicine Formula (TCMF) study has been recognized widely by medical scientists around the world. However, few researchers have analyzed and summarized the rapid growth of academic articles of TCMF published in English. The primary aim of this work was to assess the outcome of these research outputs in the TCMF field from 2000 to 2016 and to evaluate the situation and tendency. Read More

J Pediatr Urol 2019 Mar 12. Epub 2019 Mar 12.

Department of Paediatric Urology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK. Electronic address:

Laparoscopic transperitoneal technique for appendicovesicostomy was performed in a 5-year-old boy with a non-neurogenic neuropathic bladder using a transumbilical 5-mm port, two 3-mm working ports and a modified Shanfield anastomosis. Posterior extramucosal detrusorotomy and submucosal dissection was performed. The proximal appendix was spatulated and advanced into the bladder through a mucosal window using a U-stitch and fixed. Read More

Turkiye Parazitol Derg 2019 Mar;43(1):21-25

Adıyaman University Faculty of Medicine, Department of Pediatric Surgery, Adıyaman, Turkey

Objective: To evaluate the histopathological findings in appendectomy materials with infection.

Methods: Appendectomy materials with infection of 24 cases were evaluated for the presence of acute inflammation, congestion, hemorrhage, perforation, lymphoid hyperplasia (LH), necrosis, granuloma, fecalith, obliteration, hyalinization, eosinophilic infiltration and mucosal architectural distortion.

Results: The frequency of among 3222 appendectomies that were scanned for the study was 0. Read More

Tumori 2019 Apr 1:300891619839297. Epub 2019 Apr 1.

1 Department of Molecular and Clinical Medicine, "Sapienza" University of Rome, Italy.

Background:: Because of a lack of large-scale prospective studies there is no clear indication about the management of patients with small bowel adenocarcinoma (SBA). This study evaluated clinical outcome of patients diagnosed with SBA at our institution.

Methods:: Clinicopathologic features, treatments, and clinical outcome of patients diagnosed with SBA between 2006 and 2017 were retrospectively analyzed. Read More

Phlebology 2019 Mar 31:268355519837869. Epub 2019 Mar 31.

2 Department of Health Care Studies, College of Polytechnics Jihlava, Jihlava, Czech Republic.

Latin anatomical terminology of venous perforators (communications between superficial and deep venous systems of the lower limb) was adopted as late as 2001 as an appendix to the official nomenclature following the clinicians' request. Terminologia Anatomica, last version of the Latin anatomical nomenclature, published in 1998, unfortunately contains no terms concerning these veins. During the 14th World Congress of the International Union of Phlebology, a consensus document was laid to expand the nomenclature of the lower limb veins, above all 36 new terms for perforators of the lower limb, both in Latin and English languages. Read More

Zookeys 2019 19;832:35-56. Epub 2019 Mar 19.

Department of Life Science, Hanyang University, 222 Wangsipriro, Seongdonggu, Seoul, South Korea Hanyang University Seoul South Korea.

A new interstitial species, is described from littoral off the east coast of Korea (Sea of Japan). The species can be distinguished from its congeners by the number of antennular articles, shape of the male appendix masculina, setation of pereopods, and length ratio of the uropodal rami. To aid species identification a taxonomic key to all species of Menzies & Pettit, 1956 is also provided as well as a partial 16S mitochondrial ribosome RNA of the new species, which is the first genetic information for the genus. Read More

J Microbiol Immunol Infect 2019 Mar 16. Epub 2019 Mar 16.

College of Information Science and Engineering, Shandong Agricultural University, Taian 271018, China. Electronic address:

Background/purpose: The dietary fiber can regulate the intestinal mucosal immunity, and the M cell is the portal for initiating mucosal immunity. We investigated the effects of dietary fiber on the transport of Escherichia coli to assess the function of microfold (M) cells in the appendix.

Method: A total of 150 New Zealand rabbits were fed three diets (high fiber (HF): 31. Read More

Langenbecks Arch Surg 2019 Mar 29. Epub 2019 Mar 29.

Department of General, Visceral, Thoracic, Transplant and Pediatric Surgery, University Hospital Giessen, Giessen, Germany.

Purpose: Social media, especially Twitter®, is becoming increasingly important for medical topics. Systematic analyses of the content of these tweets are rare. To date, no analysis of the reception of antibiotic/non-operative-treated acute appendicitis on Twitter® has been performed. Read More

Ann Gastroenterol Surg 2019 Mar 11;3(2):202-208. Epub 2019 Jan 11.

Department of Gastroenterological Surgery Graduate School of Medicine Yokohama City University Yokohama Japan.

Background: Surgical site infection (SSI) is a common morbidity in patients undergoing colorectal surgery, and the focus of previous studies has primarily been on incisional SSI. Most reports thus far have focused on open surgery rather than on laparoscopic colorectal surgery (Lap CR). Therefore, the aim of the present study was to identify the risk factors for incisional SSI in patients undergoing elective Lap CR. Read More

J Surg Res 2019 Mar 25;240:97-103. Epub 2019 Mar 25.

Division of Pediatric Surgery, Department of Surgery, University of Texas Southwestern Medical Center, Dallas, Texas; Department of Pediatric Surgery, Children's Health, Dallas, Texas. Electronic address:

Background: Diagnostic imaging in pediatric appendicitis may decrease rates of negative appendectomy and identify alternate pathologies. We compared imaging practices for children transferred from nonpediatric facilities versus directly admitted to our tertiary children's hospital for laparoscopic appendectomy, and assessed the diagnostic accuracy in each population based on final pathologic diagnosis.

Materials And Methods: After institutional review board approval, all cases of laparoscopic appendectomy at our children's hospital during 2015 were reviewed. Read More

Medicine (Baltimore) 2019 Mar;98(13):e15006

Department of Pediatrics, Integrated Traditional Chinese and Western Medicine, Tianjin Nankai Hospital.

Rationale: Acute appendicitis is one of the most common causes of acute abdomen in children, yet it is difficult to diagnose in young children because its clinical manifestations may be atypical. Here, 3 atypical clinical cases associated with appendicitis in children are reported.

Patient Concern: The 1st case corresponds to a 5-year-old male patient who presented with abdominal discomfort, intermittent fevers, and vomiting, have increased white blood cell (WBC) count and C-reactive protein (CRP). Read More

Int J Stroke 2019 Mar 28:1747493019838760. Epub 2019 Mar 28.

3 Clinical Innovation and Research Institute Memorial Hermann Hospital, Texas Medical Center, Houston, TX, USA.

The 14th International Symposium on Thrombolysis, Thrombectomy and Acute Stroke Therapy (TTST) took place in Houston, Texas on 21-22 October 2018. Attended by 150+ invited global experts, the objectives of TTST 2018 were to explore the changing landscape of acute ischemic stroke therapy and to address current controversies in thrombolysis and thrombectomy, including expanding access and systems of care with global relevance. This article summarizes the proceedings of TTST 2018. Read More

Case Rep Surg 2019 21;2019:6091515. Epub 2019 Feb 21.

University of Maryland Community Medical Group, Surgical Care, 500 Cadmus Lane, Easton, MD 21601, USA.

Background: Gastrointestinal stromal tumor (GIST) is an uncommon tumor of the GI tract usually seen in elderly patients, often difficult to diagnose because of the unspecific symptoms such as abdominal pain and fullness. Recurrent GIST may have an even more obscure clinical presentation.

Case Report: A 44-year-old female with a history of surgically treated GIST presented to the emergency room complaining of acute onset sharp RLQ pain, nausea, and vomiting. Read More

Gan To Kagaku Ryoho 2019 Mar;46(3):518-520

Dept. of Surgery, Tokyo Women's Medical University Medical Center East.

The case was a 76-year-old man. He visited our hospital for a positive fecal occult blood test finding at a medical examination. A colonoscopy revealed a macroscopic, 30 mm, type-1 lesion in the cecum. Read More

Pleura Peritoneum 2018 Dec 2;3(4):20180123. Epub 2018 Oct 2.

Peritoneal Malignancy Institute, Basingstoke and North Hampshire Hospital, Hampshire Hospitals NHS Foundation Trust, Basingstoke, UK.

Background: To analyse the duration of parenteral nutrition (PN) in patients treated for peritoneal malignancy with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) over a 2 year period at a single UK National referral centre.

Methods: A retrospective analysis of prospective data for all patients (n=321) who underwent CRS and HIPEC for peritoneal malignancy at the Peritoneal Malignancy Institute Basingstoke between April 1, 2013 and March 31, 2015.Duration of PN was compared between primary tumour site (appendix, colorectal, mesothelioma and other); completeness of CRS (complete CRS vs. Read More

Cureus 2019 Jan 16;11(1):e3894. Epub 2019 Jan 16.

Surgery, Hôpital Maisonneuve-Rosemont, Montréal, CAN.

Appendiceal neoplasms account for 1% of appendectomy specimens. Common subtypes include mucinous cystadenoma, adenocarcinoma, and neuroendocrine tumors (NETs). The simultaneous presence of appendicular mucinous and NETs is a rare event. Read More

Ann Transplant 2019 Mar 26;24:168-173. Epub 2019 Mar 26.

Transplant Research Center, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.

BACKGROUND Clinical characteristics of acute appendicitis in kidney transplant recipients may be different from those in the general population due to kidney transplant recipient's immunosuppressive state and position change of appendix caused by graft. MATERIAL AND METHODS Clinical characteristics of 10 cases of acute appendicitis among 2880 cases of kidney transplantation were evaluated, including diagnostic rate, location of appendix and complication in kidney transplant recipients. RESULTS Acute appendicitis was suspected in 9 of 10 patients (90%) with acute appendicitis based on clinical and laboratory findings. Read More

J Am Osteopath Assoc 2019 Apr;119(4):268-272

Radiology 2019 Apr;291(1):259-260

From the Department of Radiology, Norfolk and Norwich University Hospitals, Colney Lane, Norwich NR4 7UY, England.

History A 65-year-old man presented to the emergency department with a 1-week history of constipation, which was associated with increasing abdominal distention and not passing flatus. Four weeks prior to the current admission he had been diagnosed with metastatic primary adenocarcinoma of the appendix. One week ago, he had been hospitalized with small-bowel obstruction, for which he required laparotomy and loop ileostomy. Read More

Cephalalgia 2019 Mar 20:333102419839793. Epub 2019 Mar 20.

1 Headache Unit, University Hospital of Valladolid, Valladolid, Spain.

Background: Epicrania fugax is included in the appendix of the International Classification of Headache Disorders and is characterized as recurrent brief attacks of linear or zigzag pain moving across the cranial surface, commencing and terminating in the distribution of different nerves. We present a new case of epicrania fugax in which the headache was the presenting symptom of a cerebellar abscess.

Case Report: We present a 58-year-old woman with prior history of Chiari I malformation who underwent suboccipital craniectomy. Read More

Eur J Heart Fail 2019 Mar 20. Epub 2019 Mar 20.

Department of Cardiology and Angiology, Hannover Medical School, Hannover, Germany.

Aims: Despite recent advances in the treatment of chronic heart failure (HF), mortality and hospitalizations still remain high. Additional therapies to improve mortality and morbidity are urgently needed. The efficacy of cardiac glycosides - although regularly used for HF treatment - remains unclear. Read More

Ulus Travma Acil Cerrahi Derg 2019 Mar;25(2):118-122

Department of General Surgery, University of Health Sciences, Okmeydanı Training and Research Hospital, İstanbul-Turkey.

Background: The aim of this study was to investigate the incidence of appendiceal neuroendocrine tumors (NET) in an acute appendicitis cohort, as well as to investigate the behavioral form of the tumor. Our secondary aim was to investigate survival in patients with appendiceal NET.

Methods: Between February 2006 and June 2018, 6518 appendectomies were performed for acute appendicitis in the department of surgery, University of Health Sciences, Okmeydanı Education and Research Hospital, İstanbul, Turkey. Read More