Search Our Scientific Publications & Authors

J AOAC Int 2022 Jun 29. Epub 2022 Jun 29.

Société des Produits Nestlé SA, Nestlé Research, Route du Jorat 57, 1000 Lausanne 26, Switzerland.

Background: A method for the quantification of total amino acids (including taurine and excluding tryptophan) using Ultra High Performance Liquid Chromatography separation coupled to Ultraviolet detection (UHPLC-UV) was granted First Action status (AOAC 2018.06) by the AOAC INTERNATIONAL Stakeholder Program for Infant Formula and Adult Nutritionals (SPIFAN) in 2018.

Objective: An interlaboratory study was conducted to further assess method performance against the AOAC Standard Method Performance Requirements (AOAC SMPR 2014. Read More

Inflamm Bowel Dis 2022 Jun 29. Epub 2022 Jun 29.

General Surgery and Gastroenterology Department, NHS Greater Glasgow & Clyde, Glasgow, Scotland.

Background: This updated systematic review and meta-analysis investigates the putative role of the appendix in ulcerative colitis as a therapeutic target.

Methods: Ovid Medline, Embase, PubMed and CENTRAL were searched with MeSH terms ("appendectomy" OR "appendicitis" OR "appendix") AND ("colitis, ulcerative") through October 2020, producing 1469 references. Thirty studies, including 118 733 patients, were included for qualitative synthesis and 11 for quantitative synthesis. Read More

BMC Surg 2022 Jun 27;22(1):249. Epub 2022 Jun 27.

The Second Hospital of Dalian Medical University, Zhongshan Road, Shahekou District, Dalian, Liaoning, People's Republic of China.

Background: Autoamputation of the appendix, i.e., complete separation of a part of the appendix without any surgical intervention, has been rarely documented in the literature in recent years. Read More

Wiad Lek 2022 ;75(5 pt 1):1095-1099

BOGOMOLETS NATIONAL MEDICAL UNIVERSITY, KYIV, UKRAINE.

Objective: The aim: To search for new and improvement of known methods of diagnosis and surgical treatment of atypical forms of acute appendicitis.

Patients And Methods: Materials and methods: There were analyzed the results of diagnosis and surgical treatment of 852 patients with atypical course of acute appendicitis, which amounted to 25.3% of the total number of patients in this category. Read More

J Glaucoma 2022 Jun 27. Epub 2022 Jun 27.

Sekuru Kaguvi Hospital Zimbabwe.

Purpose: To explore regional variations in the presentation of newly diagnosed glaucoma in Sub Saharan Africa (SSA).

Methodology: This was a multi-centre, cross-sectional study in which newly diagnosed, consecutive, glaucoma patients aged ≥18 years were recruited from 27 eye clinics in 10 countries throughout SSA. Demographic and ophthalmic examination data were collected. Read More

Ecology 2022 Jun 27:e3782. Epub 2022 Jun 27.

Center for Biodiversity and Climate Change, Forestry and Forest Products Research Institute, Forest Research and Management Organization, 1 Matsunosato, Tsukuba, Ibaraki 305-8687, Japan.

Rev Int Organ 2022 29;17(3):453-483. Epub 2021 May 29.

World Trade Institute, University of Bern, Bern, Switzerland.

We explore the impact of the introduction and design of labor clauses (LCs) in preferential trade agreements (PTAs) on bilateral trade flows over the period 1990-2014. While it is not a priori clear if the inclusion of LCs in PTAs will decrease or increase bilateral trade, we expect the direction of trade to matter, that is, we expect to observe the (negative or positive) impact of LCs in the South-North trade configuration. We also expect, in that configuration, stronger LCs to yield stronger (negative or positive) effects on bilateral trade flows. Read More

Cureus 2022 May 5;14(5):e24764. Epub 2022 May 5.

Pediatric Surgery, King George's Medical University (KGMU), Lucknow, IND.

Background The closure of the appendiceal stump is a crucial step during an appendectomy. The purpose of this study is to evaluate the LigaSure Vessel Sealing System in laparoscopic appendectomy (LA) for sealing and dividing the base of the appendix. Material and methods Laparoscopic appendectomy was performed using the 5-mm LigaSure Vessel Sealer in 53 patients, and the mesoappendix along with the base of the appendix was divided by LigaSure. Read More

Radiol Case Rep 2022 Sep 18;17(9):3000-3004. Epub 2022 Jun 18.

Radiology Department, National Institute of Oncology Mohamed V University, Rabat, Morocco.

Appendiceal mucocele with unprompted pseudomyxoma peritonei is a rare malignant tumor, which is difficult to diagnose before surgery. We present a case of a 62-year-old woman, and subsequently discuss the clinical and imaging presentation of mucoceles. Findings on CT scan suggested 2 diagnoses: appendiceal mucocele with pseudomyxoma peritonei and malignant ovarian tumor with peritoneal carcinosis. Read More

Int J Appl Basic Med Res 2022 Apr-Jun;12(2):140-143. Epub 2022 May 10.

Department of General Surgery, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.

Acute appendicitis is one of the most common surgical emergencies encountered. Although studies have reported a rise in the number of cases over the past decade in Western countries, appendicitis is comparatively lower in Asian countries, mainly due to the prevailing dietary habits. Acute appendicitis can further complicate as either appendicular abscess or an appendicular lump or culminate into peritonitis following gangrene/rupture. Read More

Zhonghua Wei Chang Wai Ke Za Zhi 2022 Jun;25(6):513-521

Department of Colorectal Surgery, the Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, the Sixth Affiliated Hospital, Sun Yat-sen University, Guangdong Institute of Gastroenterology, the Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China.

To analyzed perioperative safety of cytoreductive surgery (CRS) for patients with colorectal cancer peritoneal metastasis (CRPM) and to construct a predictive model for serious advese events (SAE). A descriptive case-series study was conducted to retrospectively collect the clinicopathological data and treatment status (operation time, number of organ resection, number of peritoneal resection, and blood loss, etc.) of 100 patients with peritoneal metastases from colorectal cancer or appendix mucinous adenocarcinoma who underwent CRS at the Sixth Affiliated Hospital of Sun Yat-sen University from January 2019 to August 2021. Read More

BMJ Case Rep 2022 Jun 24;15(6). Epub 2022 Jun 24.

Gynaecologic Oncology, Dr B Borooah Cancer Society Trust, Guwahati, Assam, India.

Carcinoid tumours are present in a wide range of organs but most frequently involve the gastrointestinal tract and rarely reported in gynaecological organs. Literature reports that the prevalence of ovarian carcinoid is 0.3%-1% of ovarian neoplasms and accounts for only 5% of ovarian teratomas. Read More

Inflamm Bowel Dis 2022 Jun 24. Epub 2022 Jun 24.

Centre of Excellence for Gastrointestinal Inflammation and Immunity Research, University of Alberta, Edmonton, AB, T6G 2X8, Canada.

The vermiform appendix is generally considered a redundant organ, but recent evidence suggests that the appendix could contribute to the pathogenesis of inflammatory bowel diseases, in particular ulcerative colitis (UC), and may even have a therapeutic role; however, mechanisms of the appendix involvement remain unclear. Here, we highlight current evidence on the link between the appendix and UC and consider plausible therapeutic implications. A literature search was conducted using PubMed and PubMed Central from inception to Nov 2021 using the terms "Appendix", "UC", "Appendix & UC," "Appendectomy", and "Peri-appendicular patch," including only articles published in English. Read More

Diagnostics (Basel) 2022 Jun 3;12(6). Epub 2022 Jun 3.

Department of Internal Medicine, Faculty of Medicine, Sohag University, Sohag 82725, Egypt.

In 1921; Masson and Maresch first coined the term "neurogenic appendicitis (NA)" to describe "neuroma-like" lesions in the appendix. To date, our knowledge about NA is limited; therefore, we conducted a comprehensive analysis of the literature (1921 to 2020) to examine the clinicopathological features of NA. We also addressed the pathophysiology of acute abdominal pain and fibrosis in this entity. Read More

In Vivo 2022 Jul-Aug;36(4):1982-1985

Department of Gastroenterological Surgery, Kumamoto University Graduate School of Medical Sciences, Kumamoto, Japan;

Background: Appendicitis caused by a foreign body is extremely rare. We report a case of chronic appendicitis caused by a perforating fish bone.

Case Report: The patient was a 50-year-old Japanese man. Read More

Int J Surg Case Rep 2022 Jun 18;96:107319. Epub 2022 Jun 18.

Department of Surgery, Hanyu General Hospital, Hanyushi Saitama 348-8505, Japan.

Introduction: Immediate appendectomy for acute appendicitis with abscess has a high frequency of ileocecal resection and postoperative complications compared with interval appendectomy after conservative treatment. The optimal approach to acute appendicitis with abscess remains controversial.

Presentation Of Case: A 69-year-old woman was referred to our hospital for abdominal pain. Read More

Psychol Health Med 2022 Jun 21:1-9. Epub 2022 Jun 21.

Department of Family Medicine, Rowan University School of Osteopathic Medicine, Stratford, New Jersey.

Prior studies suggest that patients with chronic conditions are more likely to develop psychiatric disorders compared to healthy individuals without any medical conditions. The objective of this study was to investigate the link between chronic conditions and psychiatric disorders. The authors hypothesize that patients with chronic conditions have a higher comorbidity of certain psychiatric disorders compared to healthy individuals. Read More

Cureus 2022 May 16;14(5):e25055. Epub 2022 May 16.

Pathology, Jawaharlal Institute of Postgraduate Medical Education & Research, Puducherry, IND.

Introduction The appendix is considered an appendage of little value and is often treated disdainfully, be it as part of evolutionary process, on a grossing table, under a microscope or while archiving specimens and slides. It is only recently, with data indicating its importance in gut immunity and as the origin of pseudomyxoma, that its space in a human body appears vindicated. Aim Our aim was to screen the histopathologic spectrum of appendix lesions observed in our hospital for rare, incidental or clinico-radiologically uncertain lesions that would help emphasize a necessary seriousness in its sampling. Read More

Wei Sheng Yan Jiu 2022 May;51(3):437-462

Beijing Center for Disease Prevention and Control, Beijing 100013, China School of Public Health, Capital Medical University, Beijing 100069, China.

Objective: To understand the distribution characteristics of 46 elements in drinking water in Ankang area of Shanxi Province.

Methods: A total of 46 elements in drinking water samples collected in Ankang area during dry and wet seasons in 2020 were determined by inductively coupled plasma mass spectrometry(ICP-MS). According to the "drinking water hygiene standards"(GB 5749-2022) and "food safety national standards". Read More

Z Evid Fortbild Qual Gesundhwes 2022 Jun 16. Epub 2022 Jun 16.

Institute of Medical Statistics and Computational Biology, Medical Faculty, University of Cologne, University Hospital Cologne, Cologne, Germany.

Background: The randomized controlled trial (RCT) is the gold standard in evidence-based medicine. However, this design may not be appropriate in every setting, so other methods or designs such as the regression discontinuity design (RDD) are required.

Method: The aim of this article is to introduce the RDD, summarise methodology in the context of health services research and present a worked example using the statistic software SPSS (Examples for R and Stata in the Appendix A). Read More

Ophthalmology 2022 Jun 16. Epub 2022 Jun 16.

VA Million Veteran Program consortium acknowledgement is provided in the appendix.

Purpose: Primary open-angle glaucoma (POAG) is a degenerative eye disease for which early treatment is critical to mitigate visual impairment and, in severe cases, irreversible blindness. POAG-associated loci individually confer incremental risk. Genetic risk score(s) (GRS) could enable POAG risk stratification. Read More

J Community Hosp Intern Med Perspect 2022 31;12(1):32-35. Epub 2022 Jan 31.

Department of Medical Education, Rochester Regional Health, Rochester, NY, USA.

Background: The Diagnostic and Statistical Manual of Mental Disorders (DSM-5) places internet Gaming disorder (IGD) in its research appendix as a potential new behavioral addiction diagnosis that requires further investigation. As part of the media campaign #HealthyAtHome, recommendation to relieve stress and anxiety during COVID-19, the World Health Organization (WHO) advocated for the playing of video games. The encouragement and expansion of playing video games may have led to the unintentional consequence of increasing the prevalence of IGD as IGD has been postulated to be a maladaptive response to stress. Read More

Surg Res Pract 2022 7;2022:8720144. Epub 2022 Jun 7.

Department of Surgery, University of Virginia Health Systems, Charlottesville, VA, USA.

Introduction: associated diarrhea (CDAD) is a major public health issue. The appendix may function as a reservoir for the intestinal microbiome, which may repopulate the intestine following enteric infections including CDAD. . Read More

Niger J Clin Pract 2022 Jun;25(6):964-966

Department of Molecular Biology, Shanxi Province Cancer Hospital/ Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University Taiyuan, Shanxi, China.

Sessile serrated adenomas (SSA) of the appendix and anaplastic carcinoma mural nodules arising in the mucinous ovarian tumors (MOT) are rare lesions. We report a case of SSA in the appendix coexisting with an anaplastic carcinoma mural nodule in MOT. No BRAC1/BRAC2 germline mutations were found in the peripheral blood sample. Read More

Am Surg 2022 Jun 15:31348221109458. Epub 2022 Jun 15.

Department of Surgery, 12343Texas Tech University Health Science Center, Lubbock, TX, USA.

Incidental appendectomy (IA) is sometimes performed in patients undergoing abdominal operations to prevent subsequent development of appendicitis. Patients who undergo laparotomy for major abdominal trauma are at high risk of developing dense adhesions, increasing the risk of future operations. Therefore, there is a potential benefit to IA for patients undergoing trauma laparotomy. Read More

BMC Surg 2022 Jun 15;22(1):229. Epub 2022 Jun 15.

Department of Gastrointestinal and HPB Surgery, University Hospital of Northern Norway, Tromsø, Norway.

Background: Appendicitis is one of the most common causes of acute abdomen. Uncomplicated appendicitis is as an inflamed appendix without perforation, gangrene or abscess formation. Recent trials show that one can safely treat uncomplicated appendicitis with antibiotics, given patient approval and appropriate follow-up. Read More

Zentralbl Chir 2022 Jun 15;147(3):244-248. Epub 2022 Jun 15.

Klinik für Viszeral-, Allgemeine-, Tumor- und Transplantationschirurgie, Universitätsklinikum Köln, Koln, Deutschland.

With an incidence of 80%, neuroendocrine neoplasia (NEN) is the most common neoplasia of the appendix. In most cases, these tumours are diagnosed as an incidental finding after appendectomy with suspected appendicitis. They are usually highly differentiated neuroendocrine tumours. Read More

Proc Biol Sci 2022 06 15;289(1976):20220400. Epub 2022 Jun 15.

Department of Zoology, University of Oxford, 11a Mansfield Road, Oxford OX1 3SZ, UK.

Food poisoning caused by (campylobacteriosis) is the most prevalent bacterial disease associated with the consumption of poultry, beef, lamb and pork meat and unpasteurized dairy products. A variety of livestock industry, food chain and public health interventions have been implemented or proposed to reduce disease prevalence, some of which entail costs for producers and retailers. This paper describes a project that set out to summarize the natural science evidence base relevant to campylobacteriosis control in as policy-neutral terms as possible. Read More

Clin Pract Cases Emerg Med 2022 May;6(2):186-188

Brown University Warren Alpert Medical School, Hasbro Children's Hospital, Department of Pediatrics and Pediatric Emergency Medicine, Providence, Rhode Island.

Case Presentation: A seven-year-old male presented to the pediatric emergency department with one day of abdominal pain. His physical exam was significant for rebound, guarding, and tenderness in the right lower quadrant, and his labs demonstrated a leukocytosis. Both a point-of-care ultrasound and radiology-performed ultrasound were concerning for acute appendicitis with a periappendiceal abscess, but on emergent laparoscopy the patient was found to have an infected urachal cyst. Read More