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J Investig Med High Impact Case Rep 2022 Jan-Dec;10:23247096221098333

Division of Cardiovascular Medicine, The University of Vermont Medical Center, Burlington, USA.

Lyme disease is commonly encountered in endemic areas of the United States harboring the causal organism . Lyme carditis can manifest in early disseminated infections, usually as atrioventricular nodal blockade. Timely antibiotic therapy typically suppresses myocardial inflammation and reverses cardiac conduction disturbances. Read More

Circ Heart Fail 2022 May 20:101161CIRCHEARTFAILURE122009566. Epub 2022 May 20.

Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, PA. (A.G.P., L.B.B., M.D.Z., G.A.).

CJEM 2022 May 19. Epub 2022 May 19.

Pediatrics, University of Toronto, Toronto, ON, Canada.

Purpose: The acquisition and interpretation of clinical results during resuscitations is common; however, this can delay critical clinical tasks, resulting in increased morbidity and mortality. This study aims to determine the impact of clinical result acquisition and interpretation by the team leader on critical task completion during simulated pediatric cardiac arrest before and after team training.

Methods: This is a secondary data analysis of video-recorded simulated resuscitation scenarios conducted during Teams4Kids (T4K) study (June 2011-January 2015); scenarios included cardiac arrest before and after team training. Read More

J Cardiol 2022 May 16. Epub 2022 May 16.

Department of Cardiology II - Electrophysiology, University Hospital Muenster, Albert-Schweitzer-Campus 1, Muenster, Germany.

Introduction: Recent studies suggest cardiac involvement with an increased incidence of arrhythmias in the setting of coronavirus disease 2019 (COVID-19). The aim of this study was to evaluate the risk of potentially lethal arrhythmias and atrial fibrillation in patients with COVID-19-induced acute respiratory distress syndrome (ARDS) and to elicit possible predictors of arrhythmia occurrence.

Methods And Results: A total of 107 patients (82 male, mean age 60 ± 12 years, median body mass index 28 kg/m) treated for COVID-19-induced ARDS in a large tertiary university hospital intensive care unit between March 2020 and February 2021 were retrospectively analyzed. Read More

JACC Clin Electrophysiol 2022 May 27;8(5):707-711. Epub 2022 Apr 27.

Electrophysiology Section, Division of Cardiology, University of Michigan, Ann Arbor, Michigan, USA.

J Interv Card Electrophysiol 2022 May 19. Epub 2022 May 19.

Department of Cardiology, Tokyo Medical and Dental University Hospital, 1-5-45 Yushima, Bunkyo-ku, 113-8510, Tokyo, Japan.

Front Cardiovasc Med 2022 2;9:870127. Epub 2022 May 2.

Department of Oncology, University Hospital Ostrava, Ostrava, Czechia.

Background And Purpose: Stereotactic arrhythmia radioablation (STAR) has been suggested as a promising therapeutic alternative in cases of failed catheter ablation for recurrent ventricular tachycardias in patients with structural heart disease. Cyberknife robotic radiosurgery system utilizing target tracking technology is one of the available STAR treatment platforms. Tracking using implantable cardioverter-defibrillator lead tip as target surrogate marker is affected by the deformation of marker-target geometry. Read More

Front Psychiatry 2022 2;13:882870. Epub 2022 May 2.

Centro Cardiologico Monzino, IRCCs, Milan, Italy.

Introduction: Takayasu's arteritis (TA) is a systemic inflammatory disease that affects aorta and its major branches. There are several cardiac manifestations of TA and an association with Takotsubo syndrome (TTS) - but not coronary vasospasm - has been previously reported. The role of emotional stress in this context is unknown. Read More

Resusc Plus 2022 Jun 9;10:100241. Epub 2022 May 9.

Anaesthetics Department, Southmead Hospital, North Bristol NHS Trust, Bristol, UK.

Background: There are increasing numbers of reports of cognitive activity, consciousness, awareness and recall related to cardiopulmonary resuscitation (CPR) and interventions such as the use of sedative and analgesic drugs during CPR.

Objectives: This scoping review aims to describe the available evidence concerning CPR-related cognitive activity, consciousness, awareness and recall and interventions such as the use of sedative and analgesic drugs during CPR.

Methods: A literature search was conducted of Medline, Embase and CINAHL from inception to 21 October 2021. Read More

Acta Cardiol 2022 May 18:1-2. Epub 2022 May 18.

Université Catholique de Louvain, CHU UCL Namur, Service de Cardiologie, Yvoir, Belgium.

J Cardiol Cases 2022 May 22;25(5):262-265. Epub 2021 Nov 22.

Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan.

Persistent left superior vena cava (PLSVC) can be problematic when device implantation is scheduled from the left side because of the technical difficulty in delivering leads. Right-sided implantation is an alternative method, but there is a risk of a high defibrillation threshold (DFT). Transvenous implantation of an implantable cardioverter defibrillator (ICD) was scheduled for a 54-year-old man with idiopathic dilated cardiomyopathy and monomorphic non-sustained ventricular tachycardia, but computed tomography revealed the presence of a PLSVC. Read More

J Interv Card Electrophysiol 2022 May 18. Epub 2022 May 18.

Section of Clinical Cardiac Electrophysiology, Division of Cardiology, Department of Medicine, Medical University of South Carolina, 171 Ashley Ave, Charleston, SC, 29425, USA.

Background: Ventricular tachycardia (VT) ablation of mid- or epicardial substrate is difficult and requires a creative approach in patients with a history of coronary bypass that precludes percutaneous epicardial catheter manipulation. The coronary venous system (CVS) provides limited access to the epicardial surface of the heart. The objective of this study is to assess the feasibility, safety, and efficacy of epicardial mapping and ablation of VT substrates from the CVS in patients with history of coronary bypass. Read More

Commun Biol 2022 May 16;5(1):470. Epub 2022 May 16.

Department of Cardiology, Shanghai Children's Hospital, School of medicine, Shanghai Jiao Tong University, Shanghai, 200062, China.

Sudden cardiac death (SCD) caused by ventricular arrhythmias is the leading cause of mortality of cardiovascular disease. Mutation in TECRL, an endoplasmic reticulum protein, was first reported in catecholaminergic polymorphic ventricular tachycardia during which a patient succumbed to SCD. Using loss- and gain-of-function approaches, we investigated the role of TECRL in murine and human cardiomyocytes. Read More

Qatar Med J 2022 9;2022(1). Epub 2022 May 9.

Hamad General Hospital, Doha, Qatar E-mail:

Background: Acute pulmonary embolism (PE) is a common and potentially life-threatening condition. This comprehensive study from a Gulf Cooperation Council (GCC) country aimed to evaluate the clinical, radiological, and outcome characteristics associated with acute PE.

Methods: This retrospective observational study analyzed data of patients with confirmed acute PE who were admitted to the largest academic tertiary center in the State of Qatar from January 1, 2014, to December 31, 2018. Read More

Front Pediatr 2022 28;10:811819. Epub 2022 Apr 28.

Department of Pediatric Intensive Care Unit, Liaocheng People's Hospital, Liaocheng, China.

Objective: To investigate the epidemiology and the effectiveness of resuscitation from cardiopulmonary arrest (CPA) among critically ill children and adolescents during pediatric intensive care unit (PICU) stay across China.

Methods: A prospective multicenter study was conducted in 11 PICUs in tertiary hospitals. Consecutively hospitalized critically ill children, from 29-day old to 18-year old, who had suffered from CPA and required cardiopulmonary resuscitation (CPR) in the PICU were enrolled (December 2017-October 2018). Read More

JACC Case Rep 2022 May 4;4(9):507-511. Epub 2022 May 4.

Department of Cardiology, Inova Heart and Vascular Institute, Falls Church, Virginia, USA.

We report the case of a patient with anomalous right coronary artery (RCA) unmasked by acute perimyocarditis who continued to have ischemic symptoms despite total resolution of perimyocarditis and required surgical intervention of the anomalous RCA. This case was further complicated by ventricular arrhythmia after surgical repair. Collaboration among different cardiac specialists was essential in this case. Read More

Front Cardiovasc Med 2022 29;9:845973. Epub 2022 Apr 29.

Department of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University, Changsha, China.

Isolated right ventricular non-compaction (RVNC) is rare yet life-threatening if left untreated, especially when accompanied by ventricular tachycardia. We describe a rare case of isolated RVNC, presenting as a prominent and excessive trabeculation of the right ventricle (RV), with an abnormal electrocardiogram. The transthoracic echocardiography, computed tomography, and ventricular angiography results clearly demonstrated an isolated spongy RV, both anatomically and functionally. Read More

Front Cardiovasc Med 2022 29;9:849113. Epub 2022 Apr 29.

Section of Cardiac Electrophysiology, Emory University, Atlanta, GA, United States.

Background: Initial studies of stereotactic body radiation therapy (SBRT) for refractory ventricular tachycardia (VT) have demonstrated impressive efficacy. Follow-up analyses have found mixed results and the role of SBRT for refractory VT remains unclear. We performed palliative, cardiac radio ablation in patients with ventricular tachycardia refractory to ablation and medical management. Read More

Front Cardiovasc Med 2022 28;9:804424. Epub 2022 Apr 28.

Cardiology Department, Regional General Hospital "F. Miulli", Bari, Italy.

Background: Awareness of radiation exposure risks associated to interventional cardiology procedures is growing. The availability of new technologies in electrophysiology laboratories has reduced fluoroscopy usage during arrhythmias ablations. The aim of this study was to describe procedures with and without X-Rays and to assess feasibility, safety, and short-term efficacy of zero fluoroscopy intervention in a high-volume center oriented to keep exposure to ionizing radiation as low as reasonably achievable. Read More

Front Cardiovasc Med 2022 27;9:829679. Epub 2022 Apr 27.

Department of Cardiology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Background: The COVID-19 pandemic has led to concerns around its subsequent impact on global health.

Objective: To investigate the health-seeking behavior, reflected by ECG utilization patterns, of patients with non-COVID-19 diseases during and after COVID-19 epidemic.

Methods: Taking advantage of the remote ECG system covering 278 medical institutions throughout Shanghai, the numbers of medical visits with ECG examinations during the lockdown (between January 23 and April 7, 2020), post-lockdown (between April 8 and December 31, 2020) and post-SARS-CoV-2 (between January 23 and April 7, 2021) periods were analyzed and compared against those during the same periods of the preceding years (2018 and 2019). Read More

Pediatr Cardiol 2022 May 15. Epub 2022 May 15.

Albert Einstein College of Medicine/Children's Hospital at Montefiore, 3415 Bainbridge Avenue, Bronx, NY, 10467, USA.

Supraventricular tachycardia (SVT) is a frequent cause of tachyarrhythmia in infants < 1 year of age and ambulatory cardiac monitoring is an important tool for diagnosis and follow-up of these patients. We retrospectively reviewed 594 infants (mean age 4.05 months, SD 3. Read More

Heart Rhythm 2022 May 11. Epub 2022 May 11.

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston TX.

Background: TANGO2 deficiency disorder (TDD) is an autosomal recessive disease associated with metabolic crisis, lethal cardiac arrhythmias, and cardiomyopathy. Data regarding treatment, management, and outcomes of cardiac manifestations of TDD are lacking.

Objective: Describe TDD-related cardiac crises. Read More

Ann Noninvasive Electrocardiol 2022 May 14:e12962. Epub 2022 May 14.

Department of Cardiology, Central Hospital of Shengli Oil Field, Dongying, China.

Background: This study aimed to investigate the electrophysiological characteristics of idiopathic ventricular arrhythmias (VAs) originating from the left ventricular posterior papillary muscles (LPPM) and explore the efficiency of catheter ablation using three-dimensional intracardiac ultrasound technology.

Methods: Twenty-seven cases of premature ventricular contraction/ventricular tachycardia (PVC/VT) originating from the left ventricular posterior papillary muscles were recorded from July 2015 to June 2019 in the Central Hospital of Shengli Oil Field and the First Affiliated Hospital of Zhengzhou University. Electrophysiological mapping and radiofrequency catheter ablation (RFCA) were performed using three-dimensional intracardiac ultrasound technology. Read More

J Clin Med 2022 Apr 26;11(9). Epub 2022 Apr 26.

Clinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum, 32545 Bad Oeynhausen, Germany.

The present study describes our experience with a new mapping approach for ventricular arrhythmia (VA) ablation in patients with structural heart disease (SHD). Consecutive patients undergoing catheter ablation for recurrent VA were analyzed. High-density mapping was conducted in all patients. Read More

Heart Lung Circ 2022 May 10. Epub 2022 May 10.

Department of Cardiology, Western Health, Melbourne, Vic, Australia.

Background: Takotsubo syndrome (TTS), an acute and usually reversible condition, is associated with both tachy- and bradyarrhythmias. Such arrhythmias can be life-threatening, e.g. Read More

Heart Rhythm 2022 May 10. Epub 2022 May 10.

Department of Nanomedicine, Houston Methodist Research Institute, Houston, TX 77030, USA; Department of Cardiovascular Surgery, Houston Methodist Research Institute, Houston, TX 77030, USA. Electronic address:

Front Physiol 2022 26;13:870435. Epub 2022 Apr 26.

Department of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.

The clinical value of non-invasive mapping system depends on its accuracy under common variations of the inputs. The View Into Ventricular Onset (VIVO) system matches simulated QRS complexes of a patient-specific anatomical model with a 12-lead ECG to estimate the origin of ventricular arrhythmias. We aim to test the performance of the VIVO system and its sensitivity to changes in the anatomical model, time marker placement to demarcate the QRS complex and body position. Read More

Front Cardiovasc Med 2022 26;9:798446. Epub 2022 Apr 26.

Department of Cardiology, Peking University Third Hospital, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, China.

Objective: This study aimed to develop a model for predicting cardiovascular events in the exercise assessment of patients with coronary heart disease after percutaneous coronary intervention (PCI) based on multidimensional clinical information.

Methods: A total of 2,455 post-PCI patients who underwent cardiopulmonary exercise testing (CPET) at the Peking University Third Hospital from January 2016 to September 2019 were retrospectively included in this study; 1,449 post-PCI patients from January 2018 to September 2019 were assigned as the development cohort; and 1,006 post-PCI patients from January 2016 to December 2017 were assigned as the validation cohort. Clinical data of patients before testing and various indicators in the exercise assessment were collected. Read More

Herzschrittmacherther Elektrophysiol 2022 May 13. Epub 2022 May 13.

Klinik für Kardiologie II-Rhythmologie, Universitätsklinikum Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Deutschland.

As with all cardiac interventions, performing left ventricular ablation requires profound knowledge of cardiac anatomy. The aim of this article is to provide an overview of left ventricular anatomy and to characterize complex and clinically relevant structures from an electrophysiologist-centered perspective. In addition to the different access routes, the trabecular network, the left ventricular outflow tract, and the left ventricular conduction system, complex anatomical structures such as the aortomitral continuity and the left ventricular summit are also explained. Read More

Herzschrittmacherther Elektrophysiol 2022 May 13. Epub 2022 May 13.

Klinik für Kardiologie II - Rhythmologie und interventionelle Elektrophysiologie, Rhön Klinikum AG Campus Bad Neustadt, Bad Neustadt, Deutschland.

The arrhythmogenic substrate in patients with Chagas cardiomyopathy, arrhythmogenic dysplasia, postmyocarditis nonischemic dilative cardiomyopathy as well as after extensive posterior or anterior wall myocardial infarction is predominantly located epicardially. This can necessitate epicardial access for an effective, substrate-based catheter ablation of the ventricular tachycardia (VT). Anterior percutaneous epicardial puncture represents the standard approach for epicardial VT ablation. Read More