22,707 results match your criteria Ventricular Septal Defect


Percutaneous major aortopulmonary collateral artery banding using a covered stent in an infant.

Interact Cardiovasc Thorac Surg 2021 May 15. Epub 2021 May 15.

Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

We report a 6-month-old infant with pulmonary atresia with ventricular septal defect who was successfully treated with a novel technique of percutaneous major aortopulmonary collateral artery (MAPCA) banding with a covered stent. He suffered from heart failure due to a residual MAPCA of 4.5 mm in diameter. Read More

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Impact of Major Residual Lesions on Outcomes After Surgery for Congenital Heart Disease.

J Am Coll Cardiol 2021 May;77(19):2382-2394

Department of Cardiology, Boston Children's Hospital, Boston, Massachusetts, USA; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.

Background: Many factors affect outcomes after congenital cardiac surgery.

Objectives: The RLS (Residual Lesion Score) study explored the impact of severity of residual lesions on post-operative outcomes across operations of varying complexity.

Methods: In a prospective, multicenter, observational study, 17 sites enrolled 1,149 infants undergoing 5 common operations: tetralogy of Fallot repair (n = 250), complete atrioventricular septal defect repair (n = 249), arterial switch operation (n = 251), coarctation or interrupted arch with ventricular septal defect (VSD) repair (n = 150), and Norwood operation (n = 249). Read More

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Membranous septal aneurysm causing severe right ventricular outflow obstruction in an adult with trisomy 18.

Cardiol Young 2021 May 14:1-2. Epub 2021 May 14.

Division of Cardiology, Children's Hospital of Michigan, Detroit, MI, USA.

Membranous ventricular septal aneurysm is a known entity but rarely causes severe right ventricular outflow obstruction. We report a 40-year-old female with trisomy 18 who developed severe right ventricular outflow obstruction caused by an enormous membranous septal aneurysm associated with unrepaired inlet ventricular septal defect with perimembranous extension. Read More

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Initial Clinical Trial of A Novel Pulmonary Valved Conduit.

Semin Thorac Cardiovasc Surg 2021 May 10. Epub 2021 May 10.

Department of Cardiac Surgery, University Hospital, University of Zürich, Switzerland.

Valved allografts and xenografts for reconstruction of the right ventricular outflow tract (RVOT) lack durability and do not grow. We report the first clinical use of a completely bioabsorbable valved conduit (Xeltis pulmonary valve - XPV) in children. Twelve children (six male), median age five (two to twelve) years and median weight 17 (10 to 43) kg, underwent RVOT reconstruction with the XPV. Read More

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Giant pseudoaneurysm that developed seven years after surgical repair of a postinfarction ventricular septal defect.

Gen Thorac Cardiovasc Surg 2021 May 11. Epub 2021 May 11.

Department of Cardiovascular Surgery, Hyogo Brain and Heart Center, 520 Saisho-ko, Himeji, Hyogo, 670-0981, Japan.

Left ventricular pseudoaneurysm is a rare complication after myocardial infarction or cardiac surgery. An 88-year-old woman who developed a left ventricular pseudoaneurysm 7 years after the repair of a postinfarction ventricular septal defect was admitted to our hospital with a complaint of a pulsatile epigastric mass, which had persisted for a month. Enhanced computed tomography revealed a large left ventricular pseudoaneurysm that extended to the subcutaneous epigastric tissue through the supra-diaphragmatic space. Read More

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Therapy of supraventricular and ventricular arrhythmias in adults with congenital heart disease-narrative review.

Cardiovasc Diagn Ther 2021 Apr;11(2):550-562

Department of Cardiology II - Electrophysiology, University Hospital Muenster, Cardiology, Muenster, Germany.

Arrhythmias are among the most common late complications in adults with congenital heart disease (ACHD) and a frequent reason for hospital admission. Both, supraventricular and ventricular arrhythmias, not only cause debilitating symptoms, but may be life-threatening by increasing risk of stroke, causing or worsening heart failure and being associated with sudden death. Substrate and risk for arrhythmia differs widely between congenital defects with specific arrhythmias being much more common in some patients than others. Read More

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Rapid diagnosis of trisomy 18 of maternal origin by quantitative fluorescent polymerase chain reaction analysis following tissue culture failure for conventional cytogenetic analysis in a fetus with holoprosencephaly, ventricular septal defect, arthrogryposis of bilateral wrists and aplasia of the thumbs.

Taiwan J Obstet Gynecol 2021 May;60(3):549-550

Department of Medical Research, MacKay Memorial Hospital, Taipei, Taiwan.

Objective: We present rapid diagnosis of trisomy 18 of maternal origin by quantitative fluorescent polymerase chain reaction (QF-PCR) analysis following tissue culture failure for conventional cytogenetic analysis in a fetus with holoprosencephaly (HPE), ventricular septal defect (VSD), arthrogryposis of bilateral wrists and aplasia of the thumbs.

Case Report: A 22-year-old, primigravid woman was referred for first-trimester ultrasound screening at 13 weeks of gestation, and the fetus was found to have HPE and VSD. The pregnancy was subsequently terminated at 14 weeks of gestation, and a malformed fetus was delivered with cebocephaly, arthrogryposis of bilateral wrists and aplasia of the thumbs. Read More

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Prenatal diagnosis of familial recessive PIGN mutation associated with multiple anomalies: A case report.

Taiwan J Obstet Gynecol 2021 May;60(3):530-533

Center of Prenatal Diagnosis, Women and Children's Hospital Affiliated to Xiamen University, PR China. Electronic address:

Objective: We present a novel homozygous splice site mutation in the PIGN gene identified by whole exome sequencing and explored the genotype-phenotype correlation.

Case Report: A healthy 32-year-old woman underwent an ultrasound at 13 + 5 weeks of gestation. The ultrasound revealed multiple anomalies again including cystic hygroma, omphalocele and a ventricular septal defect. Read More

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Recent developments in next-generation occlusion devices.

Acta Biomater 2021 May 5. Epub 2021 May 5.

Center for Composite Materials and Structures, Harbin Institute of Technology (HIT), P.O. Box 3011, No. 2 Yikuang Street, Harbin 150080, People's Republic of China. Electronic address:

Transcatheter closure has been widely accepted as a highly effective way to treat abnormal blood flows and/or embolization of thrombus in the heart. It allows the closure of four types of congenital heart defects (CHDs) and stroke-associated left atrial appendage (LAA). The four types of CHDs include atrial septal defect (ASD), patent foramen ovale (PFO), patent ductus arteriosus (PDA), and ventricular septal defect (VSD). Read More

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Aortopulmonary collateral arteries in non-cyanotic congenital heart disease.

Ann Thorac Surg 2021 May 4. Epub 2021 May 4.

Department of Pediatric Intensive Care Unit, Pediatric Cardiac Center, Chinese Academy of Medical Sciences, Fuwai Hospital, Beijing, China; Department of Pediatric Intensive Care Unit, Pediatric Cardiac Center, Fuwai Yunnan Cardiovascular Hospital, Yunnan, China. Electronic address:

Development of major aortopulmonary collateral arteries (MAPCAs) are strongly associated with cyanotic congenital heart disease. However, MAPCAs have rarely been reported in non-cyanotic congenital heart disease. We report on a rare case of a newborn originally diagnosed with an atrial septal defect, a ventricular septal defect, and pulmonary arterial hypertension, who underwent complete repair. Read More

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Aspergillus Endocarditis of Pulmonary Homograft in a Congenital Heart Disease Patient.

World J Pediatr Congenit Heart Surg 2021 May 6:2150135120988640. Epub 2021 May 6.

Department of Cardiac Surgery, Mitera Hospital, Athens, Greece.

Aspergillus endocarditis (AE) is a life-threatening condition with mortality rates approximating 80%. Herein, we describe the case of a 19-year-old patient with congenitally corrected transposition of great arteries, ventricular septal defect, and pulmonary atresia, who underwent seven cardiac surgical procedures in the past. The patient was operated for AE of a previously implanted pulmonary valve homograft associated with septic pulmonary embolism and right heart failure but succumbed to multi-organ failure three months later. Read More

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Totally anomalous pulmonary venous connection with intact atrial septum.

J Card Surg 2021 May 5. Epub 2021 May 5.

Department of Cardiothoracic and Vascular Surgery, All India Institute of Medical Sciences, New Delhi, India.

Background: Total anomalous pulmonary venous connection with intact interatrial septum is extremely rare.

Aims: In these patients, a right to left shunt through a ventricular septal defect or a patent ductus arteriosus is mandatory to maintain the systemic circulation. Mechanical or physiological restriction of shunting through these pathways results in rapid clinical deterioration. Read More

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The Incidence of Congenital Heart Defects in Offspring Among Women With Diabetes in Saudi Arabia.

Cureus 2021 Mar 31;13(3):e14225. Epub 2021 Mar 31.

Biostatistics, King Saud bin Abdulaziz University for Health Sciences, Riyadh, SAU.

Background: The risk of congenital anomalies is increased in infants of diabetic mothers (IDM). The most frequent cardiac anomalies in IDMs include ventricular septal defect, transposition of great arteries, and aortic stenosis.

Objective: Estimating the incidence of infants with congenital heart defects (CHD) whose mothers have diabetes in Saudi Arabia at a tertiary hospital in the National Guard Health Affairs (NGHA) system. Read More

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Long-term outcome after the arterial switch operation: 43 years of experience.

Eur J Cardiothorac Surg 2021 May;59(5):968-977

Department of Cardiothoracic Surgery, Leiden University Medical Center, Leiden, Netherlands.

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Objectives: The objective of this study was to assess our 43-year experience with arterial switch operation (ASO) for transposition of the great arteries (TGA) by analysing cardiac outcome measures (hospital and late mortality, reoperations and catheter interventions, significant coronary artery obstruction) and to identify risk factors for reoperation and catheter interventions.

Methods: A total of 490 patients who underwent ASO for TGA from 1977 to 2020 were included in this retrospective, single-centre study. Data on reoperation and catheter intervention of hospital survivors were estimated by the Kaplan-Meier method and compared using a long-rank test. Read More

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First Harvest of Pediatric and Congenital Heart Surgery Multicenter Database in Turkey: Novel Application of Real-Time Online Reporting.

World J Pediatr Congenit Heart Surg 2021 May;12(3):377-386

Acibadem Mehmet Ali Aydinlar University, School of Medicine, Atakent Hospital, Istanbul, Turkey.

Objectives: A new congenital heart surgery database (CKCV) with real-time online reporting function was recently developed in Turkey. All standard international parameters were used, but Aristotle Comprehensive Complexity score was modified. In this study, the first analysis of the CKCV Database is reported. Read More

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Pediatric Cardiac Surgical Patterns of Practice and Outcomes in Japan and Europe.

World J Pediatr Congenit Heart Surg 2021 May;12(3):312-319

Pediatric Cardiothoracic Surgery, Children's Memorial Health Institute, Warsaw, Poland.

Objectives: The Japan Cardiovascular Surgery Database-Congenital section (JCVSD-Congenital) and the European Congenital Heart Surgeons Association (ECHSA) Congenital Heart Surgery Database (CHSD) share the same nomenclature. We aimed at comparing congenital cardiac surgical patterns of practice and outcomes in Japan and Europe using the JCVSD-Congenital and ECHSA-CHSD.

Methods And Results: We examined Japanese (120 units, 63,365 operations) and European (96 units, 90,098 operations) data in JCVSD-Congenital and ECHSA-CHSD from 2011 to 2017. Read More

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Cyanosis in a patient after Fontan palliation due to unrecognised hepatic vein to coronary sinus communication.

Cardiol Young 2021 May 4:1-2. Epub 2021 May 4.

Division of Pediatric Cardiology, Weill Cornell Medicine/NewYork-Presbyterian Komansky Children's Hospital, New York, NY, USA.

A 6-year-old male with heterotaxia, abnormal systemic and pulmonary venous drainage, and a history of Fontan completion presented with desaturations and was found by cardiac catheterisation to have a hepatic vein to coronary sinus connection. This was successfully occluded using an Amplatzer Muscular Ventricular Septal Defect Occluder. Read More

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Successful medical management of fungal infective endocarditis post VSD closure.

Ann Card Anaesth 2021 Jan-Mar;24(1):95-98

Department of Anaesthesia and Intensive Care, PGIMER, Chandigarh, India.

Fungal infective endocarditis (IE) is uncommon in postoperative cardiac surgical patients. The fungal IE accounts for 1.3'-6. Read More

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Effectiveness of posterior aortopexy for the left pulmonary vein obstruction between the left atrium and the descending aorta.

J Card Surg 2021 May 3. Epub 2021 May 3.

Department of Pediatrics, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan-si, Republic of Korea.

Background: Left pulmonary vein (PV) obstruction can occur due to compression between the left atrium (LA) and the descending aorta (DA). One of the effective solutions for this problem is posterior aortopexy. In this study, we have reported five cases of posterior aortopexy to relieve left PV obstruction between the LA and the DA. Read More

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Outcomes After Repair of Pulmonary Atresia With Ventricular Septal Defect and Major Aortopulmonary Collateral Arteries: A Tailored Approach in a Developing Setting.

Front Cardiovasc Med 2021 14;8:665038. Epub 2021 Apr 14.

Department of Cardiovascular Surgery, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangdong, China.

Pulmonary atresia with ventricular septal defect and major aortopulmonary collateral arteries (PA/VSD/MAPCAs) is complex and diverse that has led to a variety of treatment strategies. Experience has been largely obtained in the advanced countries. The clinical diversity is greater in China. Read More

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Defibrillation Safety Margin Testing in Patients With Congenital Heart Disease: Results From the NCDR.

JACC Clin Electrophysiol 2021 Apr 22. Epub 2021 Apr 22.

Section of Cardiac Electrophysiology, Division of Cardiology, University of California-San Diego, La Jolla, California, USA.

Objectives: This study analyzed the predictors of defibrillation safety margin (DSM) testing at the time of implantable cardioverter-defibrillator (ICD) insertion and factors associated with inadequate DSM in patients with congenital heart disease (CHD).

Background: There are few data about the prevalence and safety of DSM testing in those with CHD.

Methods: A retrospective analysis was performed of all patients with atrial or ventricular septal defect, tetralogy of Fallot, transposition of the great vessels, Ebstein anomaly, or common ventricle undergoing a transvenous ICD procedure in the National Cardiovascular Data Registry (NCDR) ICD Registry from April 2010 to March 2016, and DSM testing was assessed. Read More

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Application and effects of an early childhood education machine on analgesia and sedation in children after cardiothoracic surgery.

J Cardiothorac Surg 2021 May 1;16(1):118. Epub 2021 May 1.

Department of Cardiac Surgery, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, China.

Objective: To study the effect of an early childhood education machine on sedation and analgesia in children after cardiothoracic surgery.

Methods: A prospective randomized controlled study was conducted in a provincial hospital in China. Fifty-two patients (aged from 1 to 5 years) underwent cardiothoracic surgery (including: ventricular septal defect, patent ductus arteriosus, atrial septal defect, pulmonary stenosis, pulmonary sequestration and congenital cystic adenomatoid lung malformation) were divided into the study group (n = 26) and the control group (n = 26). Read More

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Use of Levosimendan as bridge therapy to surgical correction of post-infarction ventricular septal defect: a case report.

Eur Rev Med Pharmacol Sci 2021 Apr;25(8):3296-3299

Department of Cardiovascular Medicine, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.

Objective: Ventricular septal defect (VSD) is an uncommon but frequently fatal complication following acute myocardial infarction. In medically treated patients, mortality rates exceed 90%, while the surgical repair is associated with better outcomes, even though optimal surgical timing is still under debate.

Case Report: We present the case of a 78-years-old man with no previous remarkable cardiological history admitted to our Emergency Department with the diagnosis of anterior ST-elevation myocardial infarction and significant reduction of left ventricular ejection fraction. Read More

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Ventricular septal defect and aortic hypoplasia in congenital cytomegalovirus infection: occasional finding or underdetected correlation?

J Matern Fetal Neonatal Med 2021 Apr 28:1-3. Epub 2021 Apr 28.

University of Milan, Milano, Italy.

While other viral infections occurring in early pregnancy are known to be associated with fetal cardiac malformations, little is known about CMV and its causative role. Only a few case repots have been described reporting a correlation between congenital CMV infection and cardiac defects. We report the case of a 7-day-old neonate who was referred to our Pediatric Infectivology Department for maternal cytomegalovirus (CMV) seroconversion during the first trimester of pregnancy and confirmed congenital infection. Read More

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Congenital, acquired, or both? The only two congenitally based, acquired heart diseases.

J Card Surg 2021 Apr 28. Epub 2021 Apr 28.

Department of Pediatric and Congenital Heart Surgery, Onassis Cardiac Surgery Center, Athens, Greece.

Discrete subaortic stenosis (DSS) is a type of left ventricular outflow tract obstruction whereas double-chambered right ventricle is a form of right ventricular outflow tract obstruction. Both of these cardiac malformations share lots of similar characteristics which classify them as acquired developmental heart diseases despite their congenital anatomical substrate. Both of them are frequently associated to ventricular septal defects. Read More

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A novel surgical technique to address post septal myectomy ventricular septal defect.

Ann Thorac Surg 2021 Apr 24. Epub 2021 Apr 24.

Consultant Cardiothoracic Surgery, Narayana Institute of Cardiac Sciences.

Iatrogenic ventricular septal defect is a rare complication in patients undergoing septal myectomy for hypertrophic obstructive cardiomyopathy and it necessitates closure in the post-operative period. We describe a novel surgical technique for closure of the ventricular septal defect using a biventricular approach with a custom made Polytetrafluoroethylene device. Our method is easily reproducible. Read More

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Update on shunt closure in neonates and infants.

Expert Rev Cardiovasc Ther 2021 May 11:1-18. Epub 2021 May 11.

Department of Pediatrics, Sidra Heart Center, Sidra Medicine, Doha, Qatar.

: Cardiac defects that result in shunting are the most common types of congenital heart anomalies. Although these lesions can be simple, they can cause significant hemodynamic changes and can be challenging to manage in neonates and infants. Over the recent decades, the development of new transcatheter techniques and devices has made it safe and feasible to manage such defects when indicated, even in the smallest of patients. Read More

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Complete atrioventricular block after transcatheter closure of perimembranous ventricular septal defect: a few comments based on our own experience. Authors' reply.

Kardiol Pol 2021 04 23;79(4):485-486. Epub 2021 Apr 23.

Department of Pediatric Cardiology and Congenital Heart Disease, Medical University of Gdańsk, Gdańsk, Poland

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Complete atrioventricular block after transcatheter closure of perimembranous ventricular septal defect: a few comments based on our own experience.

Kardiol Pol 2021 04 23;79(4):484-485. Epub 2021 Apr 23.

Department of Congenital Heart Defects and Pediatric Cardiology, FMS in Zabrze, Medical University of Silesia in Katowice, Silesian Center for Heart Diseases, Zabrze, Poland

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