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J Invasive Cardiol 2020 Jun;32(6):206-210

11800 Carmel Creek Road, San Diego, CA 92130 USA.

Background: Transcatheter mitral valve repair (TMVR) using the MitraClip system (Abbott Vascular) has become a world-wide, well-established therapeutic alternative to symptomatic patients with severe mitral regurgitation (MR) and prohibitive surgical risk. Currently, TMVRs are performed under general anesthesia. Herein, we aimed to present the effectiveness and safety of TMVR under moderate conscious sedation (MCS). Read More

West Afr J Med 2020 Jul-Aug;37(3):281-283

National Cardiothoracic Centre, Korle-Bu Teaching Hospital, P. O. Box KB 846, Korle-Bu, Accra, Ghana.

Background: Ventricular Septal Defect (VSD) is the commonest congenital heart disease. Without appropriate treatment, it is associated with significant morbidity and mortality. Surgical repair under cardiopulmonary bypass has been the standard treatment. Read More

Kyobu Geka 2020 Jun;73(6):441-444

Department of Cadiovascular Surgely, Odawara Cadiovascular Hospital, Odawara, Japan.

A 61-year-old man with double-chambered right ventricle( DCRV) was operated on successfully without ventriculotomy. The patient presented with cardiac murmur and electrocardiogram abnormality with exertional dyspnea. Echocardiography demonstrated double-chambered right ventricle with severe tricuspid valve regurgitation. Read More

J Artif Organs 2020 May 30. Epub 2020 May 30.

Department of Cardiovascular Surgery, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Hugstetter Strasse 55, 79106, Freiburg, Germany.

The driveline's durability is crucial for optimal long-term support with a left-ventricular assist device (LVAD). The incidence of percutaneous driveline fracture after HeartMate II LVAD implantation is low. For the first time, we describe a patient with an already repaired driveline and a massive constriction and twisting of the driveline in the area of the repair site. Read More

Am J Pathol 2020 May 28. Epub 2020 May 28.

Universidad de Buenos Aires, Facultad de Medicina-CONICET, Departamento de Patología. Instituto de Fisiopatología Cardiovascular, Buenos Aires, Argentina; Universidad Católica Argentina-CONICET, Laboratorio de Patología Cardiovascular Experimental e Hipertensión Arterial, Instituto de Investigaciones Biomédicas, Buenos Aires, Argentina. Electronic address:

We studied the role of Gal-3 in the expression of alternative activation markers (M2) on macrophage, cytokine expression and fibrosis through the temporal evolution of healing, ventricular remodeling and function after myocardial infarction (MI) in mice. Male C57BL/6J and Gal-3KO mice were subjected to permanent coronary artery ligation or sham for 1 and 4 weeks. We studied: 1) mortality; 2) macrophage infiltration and expression of markers of alternative activation at the infarct zone; 3) cytokine expression; 4) MMP-2 activity; 5) fibrosis; 6) cardiac function and remodeling. Read More

Trials 2020 May 30;21(1):447. Epub 2020 May 30.

University Clinic of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.

Background: Coronary artery diseases (CAD) remains a severe socio-economic burden in the Western world. Coronary obstruction and subsequent myocardial ischemia result in progressive replacement of contractile myocardium with dysfunctional, fibrotic scar tissue. Post-infarctional remodeling is causal for the concomitant decline of left-ventricular function and the fatal syndrome of heart failure. Read More

Catheter Cardiovasc Interv 2020 May 30. Epub 2020 May 30.

Department of Medicine/Cardiology, NorthShore University HealthSystem, Evanston, Illinois, USA.

Postinfarction ventricular septal rupture is a rare and devastating complication of myocardial infarction. Despite attempts at acute surgical and percutaneous defect closure, morbidity and mortality remain high. Herein, we describe a hybrid surgical and catheter-based approach to defect closure in a 63-year-old woman with postinfarction ventricular septal rupture and cardiogenic shock. Read More

Int J Cardiol 2020 May 26. Epub 2020 May 26.

University of Cologne, Faculty of Medicine and University Hospital Cologne, Department III of Internal Medicine, Heart Center, Germany.

Background: The generalizability of the COAPT trial results on the benefit of TMVR in patients with secondary mitral regurgitation is unclear.

Methods: Functional and long-term clinical outcome were examined in 122 consecutive patients with secondary mitral regurgitation and reduced ejection fraction undergoing TMVR. "COAPT-like" patients were defined according to principal COAPT inclusion/exclusion criteria if all of the following was fulfilled: symptomatic mitral regurgitation grade 3+ or more according to American guidelines; left ventricular ejection fraction ≥20%, left ventricular end-systolic dimension ≤70 mm, estimated pulmonary artery systolic pressure ≤70 mmHg, mitral valve orifice area ≥4 cm, no prior mitral valve procedure, no right sided congestive heart failure, no COPD requiring home oxygen therapy and NYHA class less than IVb. Read More

Yonsei Med J 2020 Jun;61(6):492-505

Division of Neonatology, Severance Children's Hospital, Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.

Purpose: To elucidate the brain's intrinsic response to injury, we tracked the response of neural stem/progenitor cells (NSPCs) located in ventricular-subventricular zone (V-SVZ) to hypoxic-ischemic brain injury (HI). We also evaluated whether transduction of V-SVZ NSPCs with neurogenic factor could enhance their neurogenesis in HI.

Materials And Methods: Unilateral HI was induced in ICR neonatal mice. Read More

Pediatr Cardiol 2020 May 28. Epub 2020 May 28.

Department of Cardiac Surgery, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, China.

This study investigated the efficacy and safety of intravenous treprostinil during the perioperative period in infants with non-restrictive ventricular septal defect (VSD) and severe pulmonary arterial hypertension (PAH) undergoing surgical VSD repair. This was a retrospective study. There were 79 infants with non-restrictive VSD and severe PAH receiving surgical treatment from January to December 2019 in our cardiac center. Read More

JACC Case Rep 2020 Apr 15;2(4):559-564. Epub 2020 Apr 15.

Section of Cardiology, Department of Medicine, University of Chicago Medical Center, Chicago, IL.

Traumatic ventricular septal defects due to penetrating cardiac injury are uncommon. Transthoracic echocardiography is an essential tool in diagnosis. Options for closure include either surgical or percutaneous repair. Read More

J Surg Case Rep 2020 Mar 17;2020(3):rjaa010. Epub 2020 Mar 17.

Division of Cardiovascular Surgery, Asahikawa Medical University, Asahikawa, Japan.

Ventricular septal rupture (VSR) is a serious and fatal mechanical complication after acute myocardial infarction. Emergent or urgent, surgical/transcatheter intervention is necessary to treat VSR, though the outcome is not favorable. We performed temporary pulmonary artery banding (PAB) in an 85-year-old man who presented with chest pain to adjust the shunt flow through the VSR, which prevented further pulmonary edema and delayed the timing of surgical repair. Read More

PLoS One 2020 28;15(5):e0232817. Epub 2020 May 28.

Department of Internal Medicine I, Klinikum St. Marien, Amberg, Germany.

Background And Objectives: MitraClip implantation is an established therapy for secondary mitral regurgitation (MR) in high-risk patients and has shown to improve several important outcome parameters such as functional capacity. Patient selection is both challenging and crucial for achieving therapeutic success. This study investigated baseline predictors of functional improvement as it was quantified by the six-minute walk distance (6MWD) after transcatheter mitral valve repair. Read More

Cardiovasc Revasc Med 2020 May 19. Epub 2020 May 19.

Division of Cardiovascular Medicine, The Ohio State University, Columbus, OH, USA.

Secondary (also known as functional) mitral regurgitation (MR) has increased substantially over the last several decades due to an increase in the prevalence of dilated cardiomyopathy (ischemic and non-ischemic). Mortality and morbidity in patients with dilated cardiomyopathy is much greater when associated with MR as compared to without MR. MR will result in further left ventricular (LV) volume overload, LV dilation, and pupillary muscle displacement resulting in deterioration of the severity of MR leading to a vicious cycle. Read More

JAMA Cardiol 2020 May 27. Epub 2020 May 27.

The BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, New York.

Importance: Myocardial replacement fibrosis has been reported to occur in one-third of patients with mitral valve prolapse (MVP) and significant mitral regurgitation (MR). However, it remains unknown whether there are detectable changes in myocardial metabolism suggestive of inflammation or ischemia that accompany the development of fibrosis.

Objectives: To characterize the burden and distribution of fluorine 18-labeled (18F) fluorodeoxyglucose (FDG) uptake and late gadolinium enhancement (LGE) in patients with degenerative MVP and ventricular ectopy. Read More

BMC Surg 2020 May 26;20(1):115. Epub 2020 May 26.

Department of Cardiovascular Surgery, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu, Sichuan, 610041, P.R. China.

Background: Treatments for perimembranous ventricular septal defects (pmVSD) mainly include conventional surgical repair (CSR), transcatheter device closure (TDC), and perventricular device closure (PDC). We aimed to perform a network meta-analysis to compare the three approaches in patients with pmVSD.

Methods: We searched for comparative studies on device closure and conventional repair for pmVSD to April 2020. Read More

Int J Mol Sci 2020 May 23;21(10). Epub 2020 May 23.

Institute for Molecular Cardiovascular Research (IMCAR), RWTH Aachen University, 52074 Aachen, Germany.

Aim: Recruitment of neutrophils to the heart following acute myocardial infarction (MI) initiates inflammation and contributes to adverse post-infarct left ventricular (LV) remodeling. However, therapeutic inhibition of neutrophil recruitment into the infarct zone has not been beneficial in MI patients, suggesting a possible dual role for neutrophils in inflammation and repair following MI. Here, we investigate the effect of neutrophils on cardiac fibroblast function following MI. Read More

Ann Thorac Surg 2020 May 23. Epub 2020 May 23.

Department of cardiovascular surgery, Kyushu university hospital. Electronic address:

Most patients with repaired tetralogy of Fallot (TOF) survive to adulthood and suffer from residual right ventricular pathology, mostly pulmonary regurgitation. Pulmonary valve replacement (PVR) is a procedure of choice to alleviate right ventricular dilatation and pulmonary regurgitation. Resternotomy is the standard approach for PVR in patients who have undergone TOF repair. Read More

Ann Thorac Surg 2020 May 23. Epub 2020 May 23.

Department of Cardiothoracic Surgery, University of Louisville. Electronic address:

Background: The presence of significant atrioventricular valve (AVV) regurgitation results in unfavorable conditions that affect the success of single ventricle (SV) multistage palliation. We report our institution's AVV repair experience.

Methods: We examined incidence of AVV repair in 603 infants who underwent initial SV palliation surgery from 2002-12. Read More

Semin Thorac Cardiovasc Surg 2020 May 22. Epub 2020 May 22.

Division of Biomedical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.

The location of the atrioventricular conduction axis in the setting of atrioventricular septal defect has previously been shown by histology and intraoperative recordings. We have now re-assessed the arrangement using phase-contrast computed tomography, aiming to provide precise measurements so as to optimize future surgical repairs. We used the system based on an X-ray Talbot grating interferometer using the beamline BL20B2 in a SPring-8 synchrotron radiation facility available in Japan. Read More

Semin Thorac Cardiovasc Surg 2020 May 22. Epub 2020 May 22.

Department of Paediatric Cardiac Surgery, Birmingham Children's Hospital, Birmingham; Institute of Clinical Sciences, University of Birmingham, Birmingham, United Kingdom.

In the setting of transposition, recognition of the variability in the morphology of the outflow tracts and the arterial trunks is essential for surgical repair. Presence of a unifying system for classification would minimize the risk of misunderstanding. We examined an archive of 142 unrepaired hearts with transposition, defined as the combination of concordant atrioventricular and discordant ventriculo-arterial connections, combined with the clinical records of 727 patients undergoing the arterial switch procedures. Read More

ESC Heart Fail 2020 May 23. Epub 2020 May 23.

Department of Internal Medicine-Cardiology, Deutsches Herzzentrum Berlin, Berlin, Germany.

Aims: The aim of this study was to compare the outcomes of surgical mitral valve repair or replacement (sMVR) and percutaneous edge-to-edge repair using MitraClip (pMVR) in patients with severe left ventricular dysfunction affected by functional mitral regurgitation (FMR).

Methods And Results: We retrospectively identified 132 patients with left ventricular ejection fraction (LVEF) ≦ 30% submitted to sMVR (n = 47) or pMVR (n = 85) for FMR at our centre from January 2013 to December 2017. To adjust for baseline imbalances, we used a propensity score matching by age, logistic EuroSCORE, and left ventricular end-systolic volume. Read More

J Neurosurg Pediatr 2020 May 22:1-7. Epub 2020 May 22.

1Keck School of Medicine of University of Southern California, Los Angeles; and Divisions of.

Preterm infants commonly present with a hemodynamically significant patent ductus arteriosus (hsPDA). The authors describe the case of a preterm infant with posthemorrhagic ventricular dilation, which resolved in a temporally coincident fashion to repair of hsPDA. The presence of a PDA with left-to-right shunting was confirmed at birth on echocardiogram and was unresponsive to repeated medical intervention. Read More

Am J Physiol Heart Circ Physiol 2020 May 22. Epub 2020 May 22.

Diabetes and Obesity Center, University of Louisville, United States.

Although cell therapy-mediated cardiac repair offers promise for treatment/management of heart failure, lack of fundamental understanding of how cell therapy works limits its translational potential. In particular, whether reparative cells from failing hearts differ from cells derived from non-failing hearts remains unexplored. Here, we assessed differences between cardiac mesenchymal cells (CMC) derived from failing (HF) versus non-failing (Sham) hearts and whether the source of donor cells (i. Read More

J Appl Physiol (1985) 2020 May 21. Epub 2020 May 21.

The Labatt Family Heart Centre, The Hospital for Sick Children and University of Toronto.

Right ventricular (RV) function impacts clinical outcomes after surgical repair of tetralogy of Fallot (rTOF). However, assessment of RV function remains difficult. We investigated the RV myocardial systolic/ diastolic (S/D) duration ratio derived from strain imaging time intervals to characterize RV myocardial performance, exploring its relation with peak oxygen consumption during exercise (VO) and cardiac magnetic resonance (CMR) derived RV dilation and function in rTOF. Read More

Gen Thorac Cardiovasc Surg 2020 May 20. Epub 2020 May 20.

Department of Cardiac Anesthesia, U. N. Mehta Institute of Cardiology and Research Center, Ahmedabad, India.

Objectives: Ebstein anomaly can be managed by single ventricular, bi-ventricular and one and a half ventricular repairs. We present midterm results of Comprehensive Tricuspid Valve repair (CTVR) with bi-directional cavo-pulmonary shunt (BCPS).

Methods: In this prospective observational study (Jan2012-July2018), 69 patients underwent surgery for Ebstein anomaly. Read More

Pediatr Crit Care Med 2020 May 20. Epub 2020 May 20.

Pediatric Cardiac Intensive Care Unit, Schneider Children's Medical Center of Israel, Petah Tikva, Israel.

Objectives: It is believed that management of neonates with dextro-transposition of the great arteries is constantly improving. Renal function may play a role in the prognosis of patients after congenital heart surgery. The aim of this study was to describe the outcome of neonates who underwent arterial switch operation during the past 2 decades using renal function as a surrogate marker for morbidity and mortality. Read More

ESC Heart Fail 2020 May 20. Epub 2020 May 20.

Transcatheter Heart Valves Department, HYGEIA Hospital, Athens, Greece.

Aims: The purpose of this study is to identify echocardiography predictors of clinical response and reverse left ventricular (LV) remodelling in patients with functional mitral regurgitation (FMR) treated with MitraClip.

Method And Results: We retrospectively analysed 86 high surgical risk patients with severe FMR; of those, 58 were implanted a MitraClip, and 28 received medical treatment and served as controls. At baseline and at 1-year follow-up, we performed clinical and echocardiography evaluation to assess global longitudinal strain (GLS) and myocardial work [global work index (GWI), global constructive work (GCW), global wasted work (GWW), global work efficiency (GWE)]. Read More

Cardiol Young 2020 May 20:1-8. Epub 2020 May 20.

Department of Surgery, Medical College of Wisconsin, Milwaukee, WI, USA.

Background: Pulmonary vascular disease resulting from CHDs may be the most preventable cause of pulmonary artery hypertension worldwide. Many children in developing countries still do not have access to early closure of clinically significant defects, and the long-term outcomes after corrective surgery remain unclear. Focused on long-term results after isolated ventricular septal defect repair, our review sought to determine the most effective medical therapy for the pre-operative management of elevated left-to-right shunts in patients with an isolated ventricular septal defect. Read More

Semin Thorac Cardiovasc Surg 2020 May 17. Epub 2020 May 17.

Unit of Cardiac Surgery, IRCCS Policlinico San Martino - University of Genoa, Genoa (GE), Italy.

Objective: Aorto-right ventricular tunnel (ARVT) is a rare cardiac congenital anomaly where an extra-cardiac channel connects the ascending aorta above the sinutubular junction to the right ventricle. This defect is caused by an abnormal development of the cushions of the aorto-pulmonary outflow tract. A case series and literature review are described. Read More

Clin Pract Cases Emerg Med 2020 May 24;4(2):154-157. Epub 2020 Feb 24.

Long Island Community Hospital, Department of Cardiology, Patchogue, New York.

A sinus of Valsalva aneurysm (SOVA) is usually a silent entity until one of its complications arises, such as heart failure. SOVA itself is uncommon, but it is more frequently associated with a supracristal ventricular septal defect (SVSD). We present a 67-year-old man with a history of an asymptomatic SVSD who presented to the emergency department with signs and symptoms of heart failure. Read More

Sci Rep 2020 May 18;10(1):8202. Epub 2020 May 18.

Arrhythmia Center, Korea University Medicine Anam Hospital, Seoul, Republic of Korea.

Atrio-esophageal fistula (AEF) is one of the most devastating complication of radiofrequency catheter ablation (RFCA) of atrial fibrillation (AF) and surgical repair is strongly recommended. However, optimal surgical approach remains to be elucidated. We retrospectively reviewed AEF cases that occurred after RFCA in a single center and evaluated the clinical results of different surgical approach. Read More

Indian J Thorac Cardiovasc Surg 2020 Mar 16:1-7. Epub 2020 Mar 16.

Department of Cardio-Vascular and thoracic surgery, S.M.S. Medical College and Group of Hospitals, Jaipur, India.

Background: At present thoracotomy with femoro-femoral bypass is an established approach for minimally invasive open heart surgeries, but thoracotomy with conventional cannulation is yet to be established. We performed 54 cases of ventricular septal defect (VSD) closure via anterolateral thoracotomy approach with central cannulation. Here we are describing our results and experience of VSD closure via anterolateral thoracotomy approach. Read More

Cardiovasc Diagn Ther 2020 Apr;10(2):208-222

Department of Cardiovascular Surgery, Second Xiangya Hospital, Central South University, Changsha 410011, China.

Background: Endomyocardial fibrosis (EMF) is a neglected cardiovascular disease of poverty which carries a poor prognosis with no specific treatment affecting mainly children and young adults. Here, we report our 10-year experience in the therapeutic management and surgical treatment for EMF.

Methods: From February 2009 to 2019 March, 55 patients diagnosed with EMF from our cardiology unit underwent surgical repair at our department's pediatric surgical division. Read More

J Am Heart Assoc 2020 Jun 16;9(11):e015737. Epub 2020 May 16.

Department of Pediatrics The Heart Institute Cincinnati Children's Hospital Medical Center University of Cincinnati College of Medicine Cincinnati OH.

The Fontan procedure has provided patients with single ventricle physiology extended survival into adulthood and in many cases has improved their quality of life. Atrioventricular valve regurgitation (AVVR) is common in single ventricle patients and is associated with increased risk of mortality. AVVR is more common in patients with a systemic tricuspid or common atrioventricular valve but is generally progressive irrespective of underlying valve morphology. Read More

Asian Cardiovasc Thorac Ann 2020 May 16:218492320927200. Epub 2020 May 16.

Department of Cardiothoracic Surgery and Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bangalore, India.

Isolated cardiac hydatid cyst is a rare entity. It warrants early surgical repair because cyst rupture is potentially fatal. We report the case of a 32-year-old lady with an epicardial ventricular hydatid cyst, which was managed successfully by complete cyst excision. Read More

J Neuropathol Exp Neurol 2020 Jun;79(6):626-640

Instituto de Anatomía, Histología y Patología.

Choroid plexus (CP) may aid brain development and repair by secreting growth factors and neurotrophins for CSF streaming to ventricular and subventricular zones. Disrupted ventricular/subventricular zone progenitors and stem cells lead to CNS maldevelopment. Exploring models, we organ cultured the CP and transplanted fresh CP into a lateral ventricle of postnatal hydrocephalic (hyHTx) and nonhydrocephalic (nHTx) rats. Read More

Can J Cardiol 2020 Mar 5. Epub 2020 Mar 5.

Department of Cardiology, Post Graduate Institute for Medical Education and Research (PGIMER), Chandigarh, India. Electronic address:

Neonates with pulmonary atresia survive only if duct patency is maintained before staged surgical repair. Ductal stenting is an effective alternative to conventional shunt surgery, as it avoids thoracotomy. With today's generation of coronary stents having better profile, flexibility, and trackability, it may be achieved safely, with less difficulty than previously described. Read More

Echocardiography 2020 May 16. Epub 2020 May 16.

Deaprtment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.

We report a case of 41-year-old woman who presented with chest tightness and shortness of breath. Transthoracic echocardiogram (TTE) showed left ventricular (LV) pseudoaneurysm of the inferior wall with preserved LV systolic function. Coronary angiogram was normal. Read More

J Thorac Cardiovasc Surg 2020 Apr 15. Epub 2020 Apr 15.

Department of Cardiovascular Surgery, Mayo Clinic, Rochester, Minn.

Objectives: To categorize and assess the functional significance of anomalous papillary muscles in patients undergoing surgical management of obstructive hypertrophic cardiomyopathy.

Methods: We reviewed the records of operations for obstructive hypertrophic cardiomyopathy and identified 73 patients with an anomalous papillary muscle. Anomalous papillary muscles inserting directly into the body of the anterior mitral valve leaflet were classified as type I, those with both direct insertion into the body of the leaflet and attachment to the free edge of the anterior leaflet were categorized as type II, and anomalous papillary muscles inserting into the free edge of the anterior leaflet were grouped as type III. Read More

Front Cardiovasc Med 2020 28;7:66. Epub 2020 Apr 28.

Department of Cardiology, Pediatric Heart Centre, Skåne University Hospital and Lund University, Lund, Sweden.

Children diagnosed with right ventricle outflow tract (RVOT) anomalies require surgical repair early in life, reoperations and lifelong follow-up. The aim is to comprehensively describe their health related quality of life (HRQoL) and to assess the agreement in this regard between children and parents. Child- and parent-reported HRQoL was assessed in 97 children aged 8-18 years using three different HRQoL questionnaires. Read More

Innovations (Phila) 2020 May 14:1556984520922978. Epub 2020 May 14.

12246 Section of Cardiac Surgery, Department of Surgery, University of Chicago Medicine, IL, USA.

The growth and advancement of minimally invasive cardiac surgery in recent years has allowed robotic and totally endoscopic procedures to become safe and effective options for the treatment of patients with various diseases of the heart. However, despite these advances, outcome data for robotic correction of congenital cardiac anomalies are scarce. This is particularly true for robotic ventricular septal defect (VSD) repair with initial experiences only recently having been published by a single group. Read More

World J Pediatr Congenit Heart Surg 2020 May 13:2150135120908208. Epub 2020 May 13.

Department of Cardiac Imaging, Inova Children's Hospital, Falls Church, VA, USA.

Left ventricular aneurysms are extremely rare in children. A child developed an aneurysm a year after recovering from idiopathic dilated cardiomyopathy. The initial management was conservative. Read More

J Cardiovasc Pharmacol 2020 Apr 16. Epub 2020 Apr 16.

Department of Cardiology, Putuo People's Hospital Affiliated to Tongji University, Shanghai, 200060, China.

Increasing evidence has confirmed that both long noncoding RNAs (LncRNAs) and microRNAs (miRNAs) exert key roles in the pathogenesis of myocardial infarction (MI). Previous microarray assay results revealed that lncRNA LNC_000898 expression was significantly downregulated in AMI. However, the specific function of LNC_000898 on MI is still unclear. Read More

Pediatr Cardiol 2020 May 11. Epub 2020 May 11.

Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China.

We determined the prevalence and factors associated with tricuspid regurgitation (TR) in adults with repair of right ventricular (RV) outflow obstruction. A total of 256 patients (128 males) were studied at 25.7 ± 7. Read More

Kyobu Geka 2020 Feb;73(2):87-91

Department of Cardiovascular Surgery, Japanese Red Cross Nagaoka Hospital, Nagaoka, Japan.

Ventricular septal perforation(VSP) is a catastrophic complication of acute myocardial infarction, and posterior VSP reportedly has worse outcomes. We present a case of a 79-year-old man with posterior VSP following acute myocardial infarction. He underwent percutaneous coronary intervention for acute postero-inferior myocardial infarction due to occlusion of the mid-portion of the right coronary artery. Read More

BMJ Open Diabetes Res Care 2020 May;8(1)

Department of Endocrinology, Diabetology and Nutrition, CHU Bordeaux, Haut Lévèque Hospital, Pessac, France.

Introduction: The offloading is crucial to heal neuropathic diabetic foot ulcer (DFU). Removable offloading are the most used devices. is a new customized removable knee-high offloading device immobilizing foot and ankle joints, with some specific and innovative features that may improve offloading. Read More

Zhonghua Yi Xue Za Zhi 2020 May;100(18):1376-1379

Department of Cardiac Surgery, Fuwai Hospital Chinese Academy of Medical Sciences Shenzhen, Shenzhen 518057, China.

To evaluate the efficacy of coronary artery bypass grafting (CABG) surgery in left ventricular dysfunction patients complicated with different degrees of ischemic mitral regurgitation (IMR). The clinical data of 525 patients (428 males and 97 females) undergoing CABG in Fuwai Hospital Chinese Academy of Medical Sciences Shenzhen, and Tianjin Medical University General Hospital between January 2015 and December 2018 were collected. The average age was (61±7) years old. Read More