6,268 results match your criteria Ventricular Premature Complexes

Potential Prognostic Impact of Frequent Premature Ventricular Complexes.

Acta Cardiol Sin 2021 May;37(3):325-326

Department of Cardiology, Centro Hospitalar Conde São Januário, Macau SAR.

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Frequency of cardiac arrhythmias in older adults: Findings from the Subclinical Atrial Fibrillation and Risk of Ischemic Stroke (SAFARIS) study.

Int J Cardiol 2021 May 6. Epub 2021 May 6.

Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, United States of America. Electronic address:

Background: Prolonged monitoring of cardiac rhythm has been used to screen for subclinical atrial fibrillation (AF); little is known about other arrhythmias in the general population, especially in the elderly, who are at higher risk of arrhythmias.

Methods: We evaluated the frequency of arrhythmias in the tri-ethnic (white, Black, Hispanic), community-based Subclinical Atrial Fibrillation and Risk of Ischemic Stroke (SAFARIS) study using a patch-based recorder for up to 14 days in 527 participants free of AF, congestive heart failure (CHF) or history of stroke. Differences according to gender, age, ethnicity and presence of hypertension, diabetes and pertinent ECG and echocardiographic variables were examined. Read More

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You cannot ablate the Lernaean Hydra: SCN5A mutation in a patient with multifocal ectopic Purkinje-related premature contractions syndrome treated with Flecainide and an implant of a subcutaneous defibrillator-a case report.

Eur Heart J Case Rep 2021 Apr 30;5(4):ytab158. Epub 2021 Apr 30.

University Hospital of Patras, Rio, Patras, 26504, Greece.

Background: SCN5A mutations may present with different clinical phenotypes such as Brugada syndrome, long QT3 syndrome, sick sinus syndrome, atrial fibrillation, dilated cardiomyopathy, and the least known multifocal ectopic Purkinje-related premature contractions syndrome.

Case Summary: We report a case of a 29-year-old woman with palpitations due to multifocal premature ventricular complexes (PVCs) and a family history of sudden death. The previous electrophysiological study had shown that PVCs arose from Purkinje fibres but catheter ablation was unsuccessful. Read More

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Validation of Adhesive Single-Lead ECG Device Compared with Holter Monitoring among Non-Atrial Fibrillation Patients.

Sensors (Basel) 2021 Apr 30;21(9). Epub 2021 Apr 30.

Department of Internal Medicine, Seoul National University Hospital, Seoul 03080, Korea.

There are few reports on head-to-head comparisons of electrocardiogram (ECG) monitoring between adhesive single-lead and Holter devices for arrhythmias other than atrial fibrillation (AF). This study aimed to compare 24 h ECG monitoring between the two devices in patients with general arrhythmia. Twenty-nine non-AF patients with a workup of pre-diagnosed arrhythmias or suspicious arrhythmic episodes were evaluated. Read More

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Obesity, Nutrition and Heart Rate Variability.

Int J Mol Sci 2021 Apr 19;22(8). Epub 2021 Apr 19.

Department of Medicine I, University Hospital Munich, Ludwig Maximilians University Munich, Marchioninistr. 15, 81377 Munich, Germany.

Heart rate variability (HRV) represents the activity and balance of the autonomic nervous system and its capability to react to internal and external stimuli. As a measure of general body homeostasis, HRV is linked to lifestyle factors and it is associated with morbidity and mortality. It is easily accessible by heart rate monitoring and gains interest in the era of smart watches and self-monitoring. Read More

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Template Beat: A Novel Marker for Left Bundle Branch Capture During Physiological Pacing.

Circ Arrhythm Electrophysiol 2021 Apr 16;14(4):e009677. Epub 2021 Apr 16.

Department of Cardiology, Geisinger Heart Institute, Wilkes Barre, PA (P.V.).

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MANual vs. automatIC local activation time annotation for guiding Premature Ventricular Complex ablation procedures (MANIaC-PVC study).

Europace 2021 Apr 13. Epub 2021 Apr 13.

Heart Institute, Teknon Medical Center, C/Vilana, 12, 08022 Barcelona, Spain.

Aims: To assess potential benefits of a local activation time (LAT) automatic acquisition protocol using wavefront annotation plus an ECG pattern matching algorithm [automatic (AUT)-arm] during premature ventricular complex (PVC) ablation procedures.

Methods And Results: Prospective, randomized, controlled, and international multicentre study (NCT03340922). One hundred consecutive patients with indication for PVC ablation were enrolled and randomized to AUT (n = 50) or manual (MAN, n = 50) annotation protocols using the CARTO3 navigation system. Read More

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Sports Activity and Arrhythmic Risk in Cardiomyopathies and Channelopathies: A Critical Review of European Guidelines on Sports Cardiology in Patients with Cardiovascular Diseases.

Medicina (Kaunas) 2021 Mar 25;57(4). Epub 2021 Mar 25.

Department of Biomedical Science and Public Health, Cardiology and Arrhythmology Clinic, University Hospital "Ospedali Riuniti Umberto I-Lancisi-Salesi", Marche Polytechnic University, 60100 Ancona, Italy.

The prediction and prevention of sudden cardiac death is the philosopher's stone of clinical cardiac electrophysiology. Sports can act as triggers of fatal arrhythmias and therefore it is essential to promptly frame the athlete at risk and to carefully evaluate the suitability for both competitive and recreational sports activity. A history of syncope or palpitations, the presence of premature ventricular complexes or more complex arrhythmias, a reduced left ventricular systolic function, or the presence of known or familiar heart disease should prompt a thorough evaluation with second level examinations. Read More

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Stepwise approach for visualization and reconstruction of pulmonary valve with intracardiac echocardiography.

Pacing Clin Electrophysiol 2021 Mar 30. Epub 2021 Mar 30.

Cardiology Department, ESTAV Toscana Sud Est, Misericordia Hospital, Grosseto, Italy.

Ventricular tachycardia and premature ventricular complexes (PVCs) arising from right ventricular outflow tract (RVOT) are the most common type of ventricular arrhythmias (VAs) in patients without structural heart disease. Radiofrequency ablation is now the gold standard of treatment in this setting due to high efficacy rates and optimal safety profile. During the last few years, the pulmonary valve (PV) and the pulmonary artery (PA) have attracted much attention as reliable sites of origin of RVOT-type arrhythmias. Read More

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RR interval analysis based on a newly developed PC program as a predictor of interventions in implantable cardioverter-defibrillator patients.

Adv Clin Exp Med 2021 Mar;30(3):279-288

National Institute of Cardiology, Warszawa, Poland.

Background: Prediction of sudden cardiac death remains a significant challenge. There is some evidence that ventricular ectopic activity could be regarded as a predictive marker.

Objectives: We carried out an analysis to explore whether premature ventricular complexes (PVCs) are a risk factor in implantable cardioverter-defibrillator (ICD) interventions. Read More

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Prospective Multicenter Assessment of a New Intraprocedural Automated System for Localizing Idiopathic Ventricular Arrhythmia Origins.

JACC Clin Electrophysiol 2021 Mar 25;7(3):395-407. Epub 2020 Nov 25.

Alliance for Cardiovascular Diagnostic and Treatment Innovation, Johns Hopkins University, Baltimore, Maryland, USA; Section of Cardiac Electrophysiology, Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, Maryland, USA.

Objectives: The objective of this study was to present a new system, the Automatic Arrhythmia Origin Localization (AAOL) system, which used incomplete electroanatomic mapping (EAM) for localization of idiopathic ventricular arrhythmia (IVA) origin on the patient-specific geometry of left ventricular, right ventricular, and neighboring vessels. The study assessed the accuracy of the system in localizing IVA source sites on cardiac structures where pace mapping is challenging.

Background: An intraprocedural automated site of origin localization system was previously developed to identify the origin of early left ventricular activation by using 12-lead electrocardiograms (ECGs). Read More

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Clinical Efficacy and Safety of Shensong Yangxin Capsule-Amiodarone Combination on Heart Failure Complicated by Ventricular Arrhythmia: A Meta-Analysis of Randomized Controlled Trials.

Front Pharmacol 2021 22;12:613922. Epub 2021 Feb 22.

Department of Cardiology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.

Shensong Yangxin capsule (SSYX) is a well-known traditional Chinese patent medicine for treating arrhythmia. Recently, a flurry of randomized controlled trials (RCTs) of SSYX combined with amiodarone (SSYX-amiodarone) was reported in the treatment of heart failure (HF) complicated by ventricular arrhythmia (VA) in China. However, these RCTs have not been systematically evaluated. Read More

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February 2021

Pre-procedural arrhythmia burden and the outcome of catheter ablation of idiopathic premature ventricular complexes.

Pacing Clin Electrophysiol 2021 Apr 15;44(4):703-710. Epub 2021 Mar 15.

Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Background: Radiofrequency catheter ablation of idiopathic premature ventricular complexes (PVCs) is an effective method for eliminating symptoms and preventing/reversing arrhythmia-induced cardiomyopathy. One reason for procedural failure is low PVC frequency during the procedure. We aimed to investigate the relation between pre-procedural PVC burden and outcome of idiopathic PVC catheter ablation. Read More

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Intermediate-coupled premature ventricular complexes and ventricular tachycardia during exercise recovery.

HeartRhythm Case Rep 2021 Feb 10;7(2):127-130. Epub 2020 Nov 10.

Division of Cardiology, Department of Pediatrics, Faculty of Medicine, University of British Columbia, Vancouver, Canada.

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February 2021

Electrophysiological study and radiofrequency ablation of hemodynamically-instable ventricular arrhythmias in a patient with pulmonary hypertension: A case report.

Medicine (Baltimore) 2021 Feb;100(8):e24896

Department of Cardiology, West China Hospital.

Introduction: Hemodynamically-instable ventricular arrhythmias (VAs) are rare in patients with pulmonary hypertension (PH). To the best of our knowledge, only 1 case has been reported so far. Moreover, the pathogenesis of this kind of arrhythmia remains obscured and its treatment is challenging. Read More

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February 2021

[Atrial and ventricular premature contractions-the "wolf in sheep's clothing"? : What is new, what is important, what to do?]

Lars Eckardt

Herzschrittmacherther Elektrophysiol 2021 Mar;32(1):1-2

Klinik für Kardiologie II - Rhythmologie, Universitätsklinikum Münster, Albert-Schweitzer Campus 1, 48149, Münster, Deutschland.

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The Role of the Left Septal Fascicle in Fascicular Arrhythmias: Clinical Presentation and Laboratory Evaluation.

JACC Clin Electrophysiol 2021 Feb 19. Epub 2021 Feb 19.

University of California-San Francisco, San Francisco, California, USA.

Objectives: This study describes a series of cases best explained by invoking the left septal fascicle (LSF) as a critical component of the arrhythmia circuit.

Background: Numerous anatomic studies have shown evidence of the LSF, but its precise role in the onset of arrhythmia is unclear.

Methods: This paper presents 5 cases that implicated the LSF as a critical component of arrhythmogenesis. Read More

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February 2021

Effect of type of diet on blood and plasma taurine concentrations, cardiac biomarkers, and echocardiograms in 4 dog breeds.

J Vet Intern Med 2021 Mar 27;35(2):771-779. Epub 2021 Feb 27.

University of Massachusetts Medical School, Worcester, Massachusetts, USA.

Background: Associations of diet with dilated cardiomyopathy are under investigation.

Objectives: That cardiac assessment would show abnormalities in healthy dogs eating grain-free (GF) diets or diets with Food and Drug Administration (FDA)-listed ingredients of concern (peas, lentils, or potatoes) as top 10 ingredients (FDA-PLP), but not in dogs eating grain-inclusive (GI) diets or diets without FDA-listed ingredients of concern (PLP) in the top 10 ingredients (NoFDA-PLP).

Animals: One hundred eighty-eight healthy Doberman Pinschers, Golden Retrievers, Miniature Schnauzers, and Whippets. Read More

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Effects of spironolactone on extrasystoles and heart rate variability in haemodialysis patients: a randomised crossover trial.

Ups J Med Sci 2021 25;126. Epub 2021 Jan 25.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

Background: Spironolactone treatment reduces mortality in haemodialysis (HD) patients. The objective of this study was to evaluate if spironolactone affects cardiac electric activity in this population.

Methods: Participants were randomised to start with spironolactone 50 mg daily or observation (12 weeks) with subsequent washout (6 weeks) and crossover to the other intervention (12 weeks). Read More

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January 2021

Similar outcomes with manual contact force ablation catheters and traditional catheters in the treatment of outflow tract premature ventricular complexes.

Europace 2021 Apr;23(4):596-602

Department of Cardiology, Semmelweis University Heart and Vascular Centre, Városmajor Street 68, H-1122 Budapest, Hungary.

Aims: Unlike in atrial fibrillation ablation, there is a lack of appropriately sized and properly designed studies regarding outflow tract (OT) premature ventricular complex (PVC) ablation outcomes with contact force sensing (CFS) catheters. We aimed to compare the acute success-, complication-, and long-term recurrence rates of manual CFS catheters with traditional irrigated catheters (T) in OT PVC ablation.

Methods And Results: Single-centre, propensity-matched data of 75-75 patients ablated for right-sided OT (RVOT) or left-sided OT (LVOT) PVCs in 2015-17 with CFS or T catheters were compared. Read More

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Long-QT founder variant T309I-Kv7.1 with dominant negative pattern may predispose delayed afterdepolarizations under β-adrenergic stimulation.

Sci Rep 2021 Feb 11;11(1):3573. Epub 2021 Feb 11.

Department of Internal Medicine and Cardiology, University Hospital Brno and Faculty of Medicine, Masaryk University, Jihlavská 20, 625 00, Brno, Czech Republic.

The variant c.926C > T (p.T309I) in KCNQ1 gene was identified in 10 putatively unrelated Czech families with long QT syndrome (LQTS). Read More

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February 2021

Prevalence, correlates, and mortality impacts of ventricular arrhythmia among older men and women: a population-based cohort study in Moscow.

BMC Cardiovasc Disord 2021 Feb 8;21(1):80. Epub 2021 Feb 8.

Max Planck Institute for Demographic Research, Konrad-Zuse-Str. 1, 18057, Rostock, Germany.

Background: In Russia, cardiovascular disease (CVD) mortality is high and the mortality gap between men and women is large. Conventional risk factors cannot explain these phenomena. Ventricular arrhythmia (VA) is an important contributor to the death toll in community-based populations. Read More

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February 2021

Short coupled torsade de pointes: Critical timing of the ventricular premature beats.

J Electrocardiol 2021 Mar-Apr;65:69-72. Epub 2021 Jan 26.

Division of Electrophysiology, Heart and Vascular Institute, Penn State Health Milton S. Hershey Medical Center, Penn State University School of Medicine, Hershey, PA, USA. Electronic address:

In this case report, we describe a 73 year old female with structuraly normal heart that developed shortcoupled torsades de pointes (TdP) resulting in an electrical storm unresponsible to several antiarrhythmic drugs, but fully controlled with verapamil. The critical timing of the ventricular premature beats that initiated TdP corresponded to those that occurred at the peak of the previous T wave. This behavior differentiates this entity from other forms of malignant ventricular arrhythmias in patients with structurally normal heart. Read More

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January 2021

[Localization of ventricular premature contractions by 12-lead ECG].

Herzschrittmacherther Elektrophysiol 2021 Mar 3;32(1):21-26. Epub 2021 Feb 3.

Klinik für Kardiologie und Rhythmologie, Evangelisches Krankenhaus Hagen-Haspe, Brusebrinkstraße 20, 58135, Hagen, Deutschland.

The advances in imaging and 3D mapping systems in the last decade allowed a better correlation of ventricular premature contractions (PVCs) with anatomical structures. With regard to PVCs, interpretation of the 12-lead ECG is still crucial for the management of patients and the planning of therapies. Although there is an armamentarium of indices and algorithms to exactly pinpoint the origin of a PVC in advance, a thorough understanding of cardiac anatomy and impulse propagation, together with an awareness of the surface ECGs limitations, provides a sufficiently close approximation. Read More

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Mapping strategies for premature ventricular contractions-activation, voltage, and/or pace map.

Herzschrittmacherther Elektrophysiol 2021 Mar 3;32(1):27-32. Epub 2021 Feb 3.

Klinik III für Innere Medizin - Allgemeine und interventionelle Kardiologie, Elektrophysiologie, Angiologie, Pneumologie und internistische Intensivmedizin, Abteilung für Elektrophysiologie, Uniklinik Köln, Kerpener Str. 62, 50937, Cologne, Germany.

A high premature ventricular contraction (PVC) burden is associated with an increase in cardiovascular mortality and may become clinically apparent through palpitations, reduced physical capacity or PVC-induced cardiomyopathy. Catheter ablation has been shown to be a more effective tool to treat patients with a high PVC burden than medical therapy alone. Current recommendations list catheter ablation as a class I option in patients with symptomatic idiopathic outflow tract PVCs as well as in patients with suspected PVC-induced cardiomyopathy. Read More

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[Prognostic significance of premature ventricular contractions : Harmless or life-threatening?]

Herzschrittmacherther Elektrophysiol 2021 Mar 1;32(1):14-20. Epub 2021 Feb 1.

Abteilung für Kardiologie und Rhythmologie, Evangelisches Krankenhaus Hagen-Haspe und Universität Witten-Herdecke, Hagen, Deutschland.

Premature ventricular contractions (PVC) are very common arrhythmias in cardiology. In structural normal hearts they usually represent a benign entity. If the ECG morphology is not consistent with idiopathic PVC, further diagnostic workup should be performed. Read More

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