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    Noninvasive positive pressure ventilation enhances the effects of aerobic training on cardiopulmonary function.
    PLoS One 2017 22;12(5):e0178003. Epub 2017 May 22.
    Department of Rehabilitation Medicine, Wakayama Medical University, Wakayama city, Wakayama, Japan.
    Purpose: The purpose of this study was to determine the effect of aerobic training under noninvasive positive pressure ventilation (NPPV) on maximal oxygen uptake ([Formula: see text]).

    Methods: Ten healthy young male volunteers participated in the study. Before the training, stroke volume (SV) and cardiac output (CO) were measured in all subjects under 0, 4, 8, and 12 cmH2O NPPV at rest. Read More

    Effect of Home Noninvasive Ventilation With Oxygen Therapy vs Oxygen Therapy Alone on Hospital Readmission or Death After an Acute COPD Exacerbation: A Randomized Clinical Trial.
    JAMA 2017 May 21. Epub 2017 May 21.
    Lane Fox Unit, Guy's and St Thomas' NHS Foundation Trust, London, England2Asthma, Allergy, and Lung Biology, King's College London, London, England.
    Importance: Outcomes after exacerbations of chronic obstructive pulmonary disease (COPD) requiring acute noninvasive ventilation (NIV) are poor and there are few treatments to prevent hospital readmission and death.

    Objective: To investigate the effect of home NIV plus oxygen on time to readmission or death in patients with persistent hypercapnia after an acute COPD exacerbation.

    Design, Setting, And Participants: A randomized clinical trial of patients with persistent hypercapnia (Paco2 >53 mm Hg) 2 weeks to 4 weeks after resolution of respiratory acidemia, who were recruited from 13 UK centers between 2010 and 2015. Read More

    Impact of Continuous Positive Airway Pressure on Left Ventricular Systolic Loading and Coronary Flow Reserve in Healthy Young Men.
    Heart Lung Circ 2017 Mar 31. Epub 2017 Mar 31.
    Department of Internal Medicine, Division of Cardiology, Pulmonology and Intensive Care Medicine, St. Vincenz Hospital, Limburg. Electronic address:
    Background: Increased augmentation index (AIx) is accompanied by an elevated cardiovascular risk. A reduction of AIx is known for long-term continuous positive airway pressure (CPAP) therapy. We hypothesised that acute preload and left ventricular workload effects AIx and subendocardial viability ratio (SEVR) as a marker of coronary flow reserve. Read More

    Pulse wave amplitude reduction as a surrogate for cortical arousal during sleep hypopnea in children.
    Sleep Med 2017 Jun 25;34:64-70. Epub 2017 Mar 25.
    Pediatric Noninvasive Ventilation and Sleep Unit, AP-HP, Hôpital Necker Enfants-Malades, Paris, France; Paris Descartes University, Paris, France; Research Unit INSERM U 955, Team 13, Créteil, France.
    Objectives: The accuracy of respiratory polygraphy (RP) is limited because of the absence of electroencephalography (EEG). Pulse wave amplitude (PWA) reduction has been shown to be a marker of autonomic activation during arousal, and may represent a substitute for obstructive respiratory-related cortical arousal (RRCA). This study tested the hypothesis that PWA could be a surrogate for RRCA in detecting obstructive hypopnea (OH) in a pediatric population. Read More

    The impact of frailty on noninvasive mechanical ventilation in elderly medical intensive care unit patients.
    Aging Clin Exp Res 2017 May 16. Epub 2017 May 16.
    Department of Pulmonary Diseases and Critical Care Unit, Gazi University Faculty of Medicine, Ankara, Turkey.
    Aim: Many factors affecting noninvasive ventilation (NIV) in critically ill patients have been reported in the literature, but there is no study about the effect of frailty. With this study, the frailty prevalence was evaluated with two different frailty scores among the NIV population of a medical intensive care unit (ICU). Besides, the impact of frailty on NIV success and mortality and its association with NIV application problems were evaluated. Read More

    Randomized crossover trial of a pressure sensing visual feedback system to improve mask fitting in noninvasive ventilation.
    Respirology 2017 May 15. Epub 2017 May 15.
    Academic Unit of Sleep and Breathing, National Heart and Lung Institute, Imperial College, London, UK.
    Background And Objective: A good mask fit, avoiding air leaks and pressure effects on the skin are key elements for a successful noninvasive ventilation (NIV). However, delivering practical training for NIV is challenging, and it takes time to build experience and competency. This study investigated whether a pressure sensing system with real-time visual feedback improved mask fitting. Read More

    [Research advances in noninvasive high-frequency oscillatory ventilation in neonates].
    Zhongguo Dang Dai Er Ke Za Zhi 2017 May;19(5):607-611
    Department of Neonatology, Children's Hospital of Fudan University, Shanghai 201102, China.
    Noninvasive ventilation is an important respiratory management technique for the treatment of mild or moderate respiratory failure in the neonatal intensive care unit. Its reasonable application can effectively avoid the use of invasive ventilation and related complications. Recent studies have found that noninvasive high-frequency oscillatory ventilation has the advantages of both nasal continuous positive airway pressure and high-frequency ventilation and can rapidly improve oxygenation, effectively remove carbon dioxide, and improve respiratory failure. Read More

    Respiratory support techniques to avoid desaturation in critically ill patients requiring endotracheal intubation: A systematic review and meta-analysis.
    J Crit Care 2017 May 8;41:98-106. Epub 2017 May 8.
    Department of Biopathology and Medical Biotechnologies (DIBIMED), Section of Anesthesia, Analgesia, Intensive Care and Emergency, University Hospital Paolo Giaccone, University of Palermo, Via del vespro 129, 90127 Palermo, Italy.
    Purpose: To evaluate which respiratory support method for critically ill patients undergoing endotracheal intubation (ETI) is associated with less desaturation.

    Methods: We searched PubMed, Cochrane Library, Scopus and CINAHL databases. We included randomized (RCT) and non-randomized (non-RCT) studies investigating any method of respiratory support before/during ETI compared to a reference control. Read More

    Characteristics, in-hospital management and outcome of late acute ST-elevation myocardial infarction presenters.
    J Cardiovasc Med (Hagerstown) 2017 May 12. Epub 2017 May 12.
    aInterventional Cardiology Unit, San Luigi Gonzaga University Hospital, Orbassano and Rivoli Hospital, Rivoli (Turin) bDivision of Cardiology, Maria Vittoria Hospital, Turin, Italy.
    Background: Patients with delayed presentation of acute myocardial infarction with ST-segment elevation (STEMI) frequently have a poor prognosis but literature about acute complications in intensive cardiac care unit (ICCU) and in-hospital outcome are still limited.

    Methods: All STEMI patients admitted to our institution between June 2007 and December 2013 were divided into patients presenting more than 12 h after symptom onset (lateSTEMI) and within 12 h (STEMI). Baselines clinical features including details about treatment of choice were collected. Read More

    The Effect of Noninvasive Positive Pressure Ventilation on Pneumonia Hospitalizations in Children With Neurological Disease.
    Child Neurol Open 2017 Jan-Dec;4:2329048X16689021. Epub 2017 Jan 10.
    Division of Respirology, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
    The aim of this retrospective single-institution observational study was to identify whether the frequency of hospitalizations for pneumonia would change before and after the initiation of noninvasive positive pressure ventilation in children with neurological conditions. Included patients were 1 to 18 years old with an underlying neurological disease and had been prescribed nocturnal noninvasive positive pressure ventilation. The authors excluded patients with a tracheostomy or those who used noninvasive positive pressure ventilation solely for obstructive sleep apnea. Read More

    Motor Neuron Disease Presenting With Acute Respiratory Failure: A Case Study.
    Ann Rehabil Med 2017 Apr 27;41(2):328-331. Epub 2017 Apr 27.
    Department of Rehabilitation Medicine, Gangnam Severance Hospital, Seoul, Korea.
    Motor neuron diseases (MNDs) refer to a heterogeneous group of progressive neurologic disorders caused by degeneration of motor neurons. The diseases affect either the upper motor neurons, lower motor neurons, or both, and are characterized by weakness, atrophy, fasciculation, spasticity, and respiratory failure. We report a case of a 61-year-old male patient with no past history of cardiovascular or pulmonary disease, who presented with only dyspnea, and no indication of any other symptom such as muscle weakness, atrophy, or bulbar dysfunction. Read More

    Acute Heart Failure in the Emergency Department: the SAFE-SIMEU Epidemiological Study.
    J Emerg Med 2017 May 10. Epub 2017 May 10.
    Department of Statistics and Quantitative Methods, University of Milano-Bicocca, Milano, Italy.
    Background: Patients with acute heart failure (AHF) have high rates of attendance to emergency departments (EDs), with significant health care costs.

    Objectives: We aimed to describe the clinical characteristics of patients attending Italian EDs for AHF and their diagnostic and therapeutic work-up.

    Methods: We carried out a retrospective analysis on 2683 cases observed in six Italian EDs for AHF (January 2011 to June 2012). Read More

    Home noninvasive positive pressure ventilation with built-in software in stable hypercapnic COPD: a short-term prospective, multicenter, randomized, controlled trial.
    Int J Chron Obstruct Pulmon Dis 2017 27;12:1279-1286. Epub 2017 Apr 27.
    Department of Respiratory Medicine, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University.
    Background: The benefits of noninvasive positive pressure ventilation (NPPV) in patients with hypercapnic COPD are controversial. It is presumed that methodology and appropriate use of NIV ventilator might be crucial for the outcomes. With the new built-in software, the performance of NIV can be monitored at home, which can guarantee the compliance and appropriate use. Read More

    Pulmonary infection control window as a switching point for sequential ventilation in the treatment of COPD patients: a meta-analysis.
    Int J Chron Obstruct Pulmon Dis 2017 24;12:1255-1267. Epub 2017 Apr 24.
    Department of Respiratory and Critical Care Medicine, The Affiliated Hospital, Institute of Respiratory Diseases, Guangdong Medical University, Zhanjiang, China.
    Purpose: Choosing the appropriate time to switch to noninvasive positive-pressure ventilation (NPPV) plays a crucial role in promoting successful weaning. However, optimal timing for transitioning and weaning patients from mechanical ventilation (MV) to NPPV has not been clearly established. In China, the pulmonary infection control (PIC) window as a switching point for weaning from MV has been performed for many years, without definitive evidence of clinical benefit. Read More

    [Choosing wisely recommendations in intensive care medicine].
    Internist (Berl) 2017 May 9. Epub 2017 May 9.
    Arbeitsbereich Notfallmedizin/Rettungsstellen/CPU, Campus Virchow-Klinikum und Charité Mitte, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13363, Berlin, Deutschland.
    Intensive care medicine is an important and integral part of internal medicine. Modern intensive care medicine permits survival of many patients with severe and life-threatening internal diseases in acute situations. Decisive for therapeutic success is often not the application of complicated and expensive medical technologies, but rather the rapid diagnosis and identification of core issues, with immediate and competent initiation of standard treatment regimens. Read More

    Obesity and perioperative noninvasive ventilation in bariatric surgery.
    Minerva Chir 2017 Jun;72(3):248-264
    Department of Medicine, Anesthesiology and Intensive Care, University of Padua, Padua, Italy.
    The incidence and prevalence of obesity continues to increase globally. Physicians will therefore provide care for an increasing number of obese patients in their clinical practice. Optimal management of these patients is required to minimize the risk of perioperative complications that increase morbidity and mortality. Read More

    [Effect of home noninvasive positive pressure ventilation on patients with severe stable chronic obstructive pulmonary disease: a meta-analysis].
    Zhonghua Jie He He Hu Xi Za Zhi 2017 May;40(5):354-362
    Department of Respiratory Medicine, First Affiliated Hospital, China Medical University, Shenyang 110001, China.
    Objective: To evaluate the effect of home noninvasive positive pressure ventilation (NPPV) on patients with severe stable chronic obstructive pulmonary disease(COPD) by meta-analysis. Methods: The data of this meta-analysis was retrieved from the PubMed, EMBASE, Cochrane library, Wanfang, Weipu and CNKI databases from January 1980 to January 2016. Randomized controlled trials (RCTs) on comparison of the effect of home NPPV in patients with severe stable COPD were enrolled. Read More

    Risk of Unsuccessful Noninvasive Ventilation for Acute Respiratory Failure in Heterogeneous Neuromuscular Diseases: A Retrospective Study.
    Neurol Int 2017 Feb 28;9(1):6904. Epub 2017 Mar 28.
    Department of Neurology, Nara Medical University, Kashihara, Japan.
    If invasive ventilation can be avoided by performing noninvasive mechanical ventilation (NIV) in patients with acute respiratory failure (ARF), the disease can be effectively managed. It is important to clarify the characteristics of patients with neuromuscular diseases in whom initial NIV is likely to be unsuccessful. We studied 27 patients in stable neuromuscular condition who initially received NIV to manage fatal ARF to identify differences in factors immediately before the onset of ARF among patients who receive continuous NIV support, patients who are switched from NIV to invasive ventilation, and patients in whom NIV is discontinued. Read More

    Airways and Injuries: Protecting Our Pediatric Patients from Respiratory Device-Related Pressure Injuries.
    Crit Care Nurs Clin North Am 2017 Jun 2;29(2):187-204. Epub 2017 Apr 2.
    Department of Nursing, Children's Hospital of Philadelphia, 3401 Civic Center Boulevard, Main Hospital A282, Philadelphia, PA 19104, USA.
    Pressure injury prevention is required in all health care environments. Respiratory technology includes invasive and noninvasive positive pressure ventilation methods of support and life-saving equipment. Pressure injury can occur from tracheostomy tubes and their securement devices, or use of noninvasive positive pressure ventilation interfaces or the head gear. Read More

    AJRCCM: 100-Year Anniversary. Homeward Bound: A Centenary of Home Mechanical Ventilation.
    Am J Respir Crit Care Med 2017 May;195(9):1140-1149
    National Institute for Health Research Respiratory Biomedical Research Unit, Royal Brompton & Harefield National Health Service Foundation Trust, London, United Kingdom.
    The evolution of home mechanical ventilation is an intertwined chronicle of negative and positive pressure modes and their role in managing ventilatory failure in neuromuscular diseases and other chronic disorders. The uptake of noninvasive positive pressure ventilation has resulted in widespread growth in home ventilation internationally and fewer patients being ventilated invasively. As with many applications of domiciliary medical technology, home ventilatory support has either led or run in parallel with acute hospital applications and has been influenced by medical and societal shifts in the approach to chronic care, the creation of community support teams, a preference of recipients to be treated at home, and economic imperatives. Read More

    Significance of NT-pro-BNP in acute exacerbation of COPD patients without underlying left ventricular dysfunction.
    Int J Chron Obstruct Pulmon Dis 2017 13;12:1183-1189. Epub 2017 Apr 13.
    Division of Pulmonary and Critical Care Medicine, Bronx-Lebanon Hospital Center, Icahn School of Medicine at Mount Sinai.
    Background: B-type natriuretic peptide (BNP) and the N-terminal fragment of pro-BNP (NT-pro-BNP) are established biomarkers of heart failure. Increased levels of natriuretic peptide (NP) have been associated with poor outcomes in acute exacerbation of COPD (AECOPD); however, most studies did not address the conditions that can also increase NT-pro-BNP levels. We aimed to determine if NT-pro-BNP levels correlate with outcomes of AECOPD in patients without heart failure and other conditions that can affect NT-pro-BNP levels. Read More

    Diaphragm Muscle Surface Electromyography in Patients Submitted to Liver Transplant and Eligible for Extubation.
    Transplant Proc 2017 May;49(4):829-831
    Unit of Liver Transplantation, Faculty of Medical Sciences, State University of Campinas, Campinas, Brazil. Electronic address:
    Introduction: Liver disease induces many organic and metabolic changes, leading to malnutrition and weight and muscular function loss. Surface electromyography is an easily applicable, noninvasive study, through which the magnitudes of the peaks on the charts depict voluntary muscle activity.

    Aim: To evaluate the diaphragmatic surface electromyography of postoperative liver transplantation subjects. Read More

    One-year and long-term mortality in patients hospitalized for chronic obstructive pulmonary disease.
    J Thorac Dis 2017 Mar;9(3):636-645
    Medicine Department, University of Santiago de Compostela, Santiago de Compostela, Spain.
    Background: Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Identifying potentially-modifiable predictors of mortality could help optimize COPD patient management. The aim of this study is to determine long-term mortality following hospitalization due to acute exacerbations of COPD (AECOPD), as well as AECOPD mortality predictors. Read More

    Assessment of perioperative minute ventilation in obese versus non-obese patients with a non-invasive respiratory volume monitor.
    BMC Anesthesiol 2017 Apr 26;17(1):61. Epub 2017 Apr 26.
    Massachusetts General Hospital, Harvard Medical School, 55 Fruit St, Boston, MA, 02114, USA.
    Background: Monitoring the adequacy of spontaneous breathing is a major patient safety concern in the post-operative setting. Monitoring is particularly important for obese patients, who are at a higher risk for post-surgical respiratory complications and often have increased metabolic demand due to excess weight. Here we used a novel, noninvasive Respiratory Volume Monitor (RVM) to monitor ventilation in both obese and non-obese orthopedic patients throughout their perioperative course, in order to develop better monitoring strategies. Read More

    Motor neurone disease: progress and challenges.
    Med J Aust 2017 May;206(8):357-362
    Brain and Mind Centre, University of Sydney, Sydney, NSW.
    Major progress has been made over the past decade in the understanding of motor neurone disease (MND), changing the landscape of this complex disease. Through identifying positive prognostic factors, new evidence-based standards of care have been established that improve patient survival, reduce burden of disease for patients and their carers, and enhance quality of life. These factors include early management of respiratory dysfunction with non-invasive ventilation, maintenance of weight and nutritional status, as well as instigation of a multidisciplinary team including neurologists, general practitioners and allied health professionals. Read More

    Evaluation of a Pediatric Early Warning Score Across Different Subspecialty Patients.
    Pediatr Crit Care Med 2017 Apr 25. Epub 2017 Apr 25.
    1Division of Critical Care Medicine, Children's National Health System, Washington, DC. 2Division of Critical Care Medicine, George Washington School of Medicine, Washington, DC. 3Department of Critical Care Medicine, Children's Hospital Los Angeles, Los Angeles, CA. 4Division of Pediatric Critical Care Medicine, University of Virginia School of Medicine, Charlottesville, VA.
    Objective: To evaluate the ability of a Pediatric Early Warning Score to predict deterioration in different subspecialty patient populations.

    Design: Single center, retrospective cohort study. Patients were classified into five groups: 1) cardiac; 2) hematology/oncology/bone marrow transplant; 3) surgical; 4) neurologic; and 5) general medical. Read More

    Use of noninvasive ventilation in severe acute respiratory distress syndrome due to accidental chlorine inhalation: a case report.
    Rev Bras Ter Intensiva 2017 Jan-Mar;29(1):105-110
    Programa de Residência em Medicina Intensiva, Hospital Universitário Getúlio Vargas, Universidade Federal do Amazonas - Manaus (AM), Brasil.
    Acute respiratory distress syndrome is characterized by diffuse inflammatory lung injury and is classified as mild, moderate, and severe. Clinically, hypoxemia, bilateral opacities in lung images, and decreased pulmonary compliance are observed. Sepsis is one of the most prevalent causes of this condition (30 - 50%). Read More

    Effect of Aerobic Exercise Training on Ventilatory Efficiency and Respiratory Drive in Obese Subjects.
    Respir Care 2017 Apr 25. Epub 2017 Apr 25.
    EA-3300 :APERE, Exercise Physiology and Rehabilitation Laboratory, Picardie Jules Verne University, Sport Sciences Department, Avenue Paul Claudel, F-80025, Amiens Cedex, France.
    Background: Obese patients show a decline in exercise capacity and diverse degrees of dyspnea in association with mechanical abnormalities, increased ventilatory requirements secondary to the increased metabolic load, and a greater work of breathing. Consequently, obese patients may be particularly predisposed to the development of respiratory muscle fatigue during exercise. The aim of this study was to assess inspiratory muscle performance during incremental exercise in 19 obese male subjects (body mass index 41 ± 6 kg/m(2)) after aerobic exercise training using the noninvasive, inspiratory muscle tension-time index (TT0. Read More

    2016 Year in Review: Noninvasive Ventilation.
    Respir Care 2017 May;62(5):623-628
    St. Michael's Hospital, Toronto, Ontario, Canada.
    Noninvasive ventilation (NIV) is an important modality in clinical practice and is extensively studied. The growth of literature related to NIV over the past 20 years has made it difficult for clinicians to stay up to date with current best practice. This article will summarize some of the important NIV literature published in 2016 and describe any impact it may have related to the clinical use of NIV. Read More

    Noninvasive Ventilation in Acute Hypoxemic Nonhypercapnic Respiratory Failure: A Systematic Review and Meta-Analysis.
    Crit Care Med 2017 Apr 22. Epub 2017 Apr 22.
    1Department of Critical Care Medicine, Nanjing Zhong-da Hospital, School of Medicine, Southeast University, Nanjing, P. R. China. 2Department of Pain Management, Subei People's Hospital of Jiangsu Province and Clinical Medical School, Yang Zhou University, Yangzhou, P. R. China.
    Objective: To evaluate the effectiveness of noninvasive ventilation in patients with acute hypoxemic nonhypercapnic respiratory failure unrelated to exacerbation of chronic obstructive pulmonary disease and cardiogenic pulmonary edema.

    Data Sources: PubMed, EMBASE, Cochrane library, Web of Science, and bibliographies of articles were retrieved inception until June 2016.

    Study Selection: Randomized controlled trials comparing application of noninvasive ventilation with standard oxygen therapy in adults with acute hypoxemic nonhypercapnic respiratory failure were included. Read More

    Clinical and polysomnographic features of children evaluated with polysomnography in pediatric sleep laboratory.
    Turk Pediatri Ars 2017 Mar 1;52(1):23-29. Epub 2017 Mar 1.
    Department of Pediatrics, Division of Pediatric Chest Diseases, Marmara University, Pendik Education and Research Hospital, İstanbul, Turkey.
    Aim: Sleep disordered breathing is a common problem in childhood that encompasses a spectrum of disorders extending from primary snoring to obstructive sleep apnea. This study aims to investigate the results of children undergoing evaluation with polysomnography in the sleep laboratory of a tertiary care hospital.

    Material And Methods: Demographic and clinical features as well as sleep associated symptoms, scores of pediatric sleep questionnaire and Pittsburgh sleep quality index and polysomnography results are retrospectively evaluated. Read More

    Low-Dose Morphine for Dyspnea in Terminally Ill Patients with Idiopathic Interstitial Pneumonias.
    J Palliat Med 2017 Feb 16. Epub 2017 Feb 16.
    3 Clincal Research Center, National Hospital Organization Kinki-Chuo Chest Medical Center , Osaka, Japan .
    Background: Dyspnea is highly prevalent in patients with idiopathic interstitial pneumonias (IIPs).

    Objective: The objective of this study is to examine the effectiveness and safety of continuous subcutaneous morphine for dyspnea in terminally ill IIP patients.

    Setting/subjects: We retrospectively reviewed cases of terminally ill IIP patients who received continuous subcutaneous morphine for dyspnea. Read More

    Risk factors for noninvasive ventilation failure in patients with acute cardiogenic pulmonary edema: A prospective, observational cohort study.
    J Crit Care 2017 Apr 13. Epub 2017 Apr 13.
    Department of Respiratory and Critical Care Medicine, Beijing Engineering Research Center of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China. Electronic address:

    Effect of High-Flow Nasal Cannula Oxygen Therapy Versus Conventional Oxygen Therapy and Noninvasive Ventilation on Reintubation Rate in Adult Patients After Extubation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    J Intensive Care Med 2017 Jan 1:885066617705118. Epub 2017 Jan 1.
    1 Department of Critical Care Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
    Purpose: We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to evaluate the effect of high-flow nasal cannula (HFNC) on reintubation in adult patients.

    Procedures: Ovid Medline, Embase, and Cochrane Database of Systematic Reviews were searched up to November 1, 2016, for RCTs comparing HFNC versus conventional oxygen therapy (COT) or noninvasive ventilation (NIV) in adult patients after extubation. The primary outcome was reintubation rate, and the secondary outcomes included complications, tolerance and comfort, time to reintubation, length of stay, and mortality. Read More

    Prospective Multicentre Study on the Epidemiology and Current Therapeutic Management of Severe Bronchiolitis in Spain.
    Biomed Res Int 2017 22;2017:2565397. Epub 2017 Mar 22.
    Unidad de Cuidados Intensivos Pediátricos, Complejo Hospitalario de Pamplona, Pamplona, Spain.
    Objective. To determine the epidemiology and therapeutic management of patients with severe acute bronchiolitis (AB) admitted to paediatric intensive care units (PICUs) in Spain. Design. Read More

    Sleep: A Window Into Autonomic Control in Children Born Preterm and Growth Restricted.
    Sleep 2017 May;40(5)
    The Ritchie Centre, Hudson Institute of Medical Research, Melbourne, Australia.
    Study Objectives: Preterm birth and fetal growth restriction (FGR) are both associated with risk of hypertension in adulthood. Mechanisms leading to this pathology are unclear. In children aged 5-12 years, who were born preterm and FGR, we used sleep as a tool to assess autonomic control with assessment of cardiovascular structure and function. Read More

    The Use of Noninvasive Positive Pressure Ventilation following Pediatric Tonsillectomy.
    Otolaryngol Head Neck Surg 2017 Apr 1:194599817701718. Epub 2017 Apr 1.
    1 University of Pennsylvania, Philadelphia, Pennsylvania, USA.
    Objective To determine the risks of bleeding and other complications in pediatric patients who require noninvasive positive pressure ventilation (PPV) in the immediate posttonsillectomy period. Study Design Case series with chart review. Setting Single tertiary pediatric hospital. Read More

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