46,900 results match your criteria Ventilation Mechanical


The Acute Respiratory Distress Syndrome after Out-of-Hospital Cardiac Arrest: Incidence, Risk Factors, and Outcomes.

Resuscitation 2019 Jan 14. Epub 2019 Jan 14.

Division of Pulmonary, Critical Care, and Sleep Medicine, Harborview Medical Center, University of Washington, Seattle, WA, United States.

Objective: To define the incidence of the acute respiratory distress syndrome (ARDS) following out-of-hospital cardiac arrest (OHCA) and characterize its impact on outcome.

Methods: This was a retrospective cohort study conducted at two urban, tertiary, academic hospitals from 2007-2014. We included adults with non-traumatic OHCA and survived for ≥48 hours. Read More

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http://dx.doi.org/10.1016/j.resuscitation.2019.01.009DOI Listing
January 2019

The Life Course Health Development Model: A Theoretical Research Framework for Pediatric Delirium.

J Clin Nurs 2019 Jan 17. Epub 2019 Jan 17.

The Ohio State University College of Nursing.

Aims And Objectives: The purpose of this article is to create a framework for future research through application and critique of the Life Course Health Development Model to the phenomenon of pediatric delirium.

Background: Delirium in the pediatric intensive care unit is associated with increased duration of mechanical ventilation, length of stay, and mortality. Nurses are uniquely positioned at the bedside to identify, prevent, and treat delirium. Read More

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http://dx.doi.org/10.1111/jocn.14776DOI Listing
January 2019

Fluid restriction reduces pulmonary edema in a model of acute lung injury in mechanically ventilated rats.

PLoS One 2019 17;14(1):e0210172. Epub 2019 Jan 17.

Pediatric Intensive Care Unit, Emma Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands.

Experimental acute lung injury models are often used to increase our knowledge on the acute respiratory distress syndrome (ARDS), however, existing animal models often do not take into account the impact of specific fluid strategies on the development of lung injury. In contrast, the current literature strongly suggests that fluid management strategies have a significant impact on clinical outcome of patients with ARDS. Thus, it is important to characterize the role of fluid management strategies in experimental models of lung injury. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0210172PLOS
January 2019

Carbon Nanocoil-Based Fast-Response and Flexible Humidity Sensor for Multifunctional Applications.

ACS Appl Mater Interfaces 2019 Jan 17. Epub 2019 Jan 17.

College of Electronic Science and Technology , Shenzhen University , 3688 Nanhai Boulevard , Shenzhen 518060 , China.

Carbon nanocoils (CNCs) are employed to fabricate fast, high-resolution, and reversible humidity sensor based on a flexible liquid crystal polymer (LCP) substrate. The humidity sensor displays fast-response (1.9 s) and recovery time (1. Read More

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http://dx.doi.org/10.1021/acsami.8b18599DOI Listing
January 2019

Multidrug resistant Gram-negative infections in neonatology.

Arch Argent Pediatr 2019 Feb;117(1):6-11

Servicio de Neonatología, Hospital de Pediatría J. P. Garrahan, Ciudad Autónoma de Buenos Aires, Argentina.

Introduction: Multidrug resistant Gramnegative (MDRGN) infections are an increasing problem in neonatal intensive care units. The objective of this study was to establish the epidemiological, clinical, microbiological, and evolutionary characteristics of carbapenem-resistant MDRGN infections and the risk factors for them at the Division of Neonatology of a tertiary care hospital.

Population And Method: A retrospective cohort study was done in this Division in patients with a documented MDRGN infection between 4/24/2013 and 4/29/2015. Read More

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http://dx.doi.org/10.5546/aap.2018.eng.6DOI Listing
February 2019

Impact of hyperoxia on cardiac pathophysiology.

J Cell Physiol 2019 Jan 16. Epub 2019 Jan 16.

Department of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, Florida.

Mechanical ventilation with high oxygen therapy (hyperoxia) is widely implemented in critical care and ICU settings. Although supplemental oxygen is beneficial to treat hypoxia, its use is also associated with poor outcomes and high mortality in patients. Lung injury due to hyperoxia exposure has been well-documented in patients, including in adults and neonates. Read More

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http://dx.doi.org/10.1002/jcp.28136DOI Listing
January 2019

Impact of Time Interval Between Glenn and Fontan Procedures on Fontan Operative and Long-Term Follow-up Results.

Pediatr Cardiol 2019 Jan 16. Epub 2019 Jan 16.

Department of Congenital Heart Disease, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 167 North Lishi Road, Xicheng District, Beijing, China.

Objective: The bidirectional cavopulmonary shunt (BCPS) is an effective palliative procedure which has been widely used to boost outcome of the Fontan procedure. However, there is no standard duration time between these two procedures. Therefore, we investigated whether different time intervals between BCPS and Fontan procedure affects morbidity and mortality of Fontan patients. Read More

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http://dx.doi.org/10.1007/s00246-018-2049-7DOI Listing
January 2019

Evaluation of Secretion-Clearing Device in Reducing Airway Resistance within Endotracheal Tubes.

Crit Care Res Pract 2018 10;2018:3258396. Epub 2018 Dec 10.

School of Dentistry, West Virginia University, Morgantown, WV, USA.

Background: Secretions accumulate in endotracheal tubes' (ETT) lumens upon their placement in patients. The secretions impact airway resistance and pressure. Secretions potentiate prolonged mechanical ventilation and ventilator-associated pneumonia. Read More

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http://dx.doi.org/10.1155/2018/3258396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311789PMC
December 2018

Physical restraints in intensive care units: a national questionnaire survey of physical restraint use for critically ill patients undergoing invasive mechanical ventilation in Japan.

Acute Med Surg 2019 Jan 6;6(1):68-72. Epub 2018 Dec 6.

Emergency Medicine and Critical Care Medicine School of Medicine St. Marianna Medical University Kawasaki Japan.

Aims: Physical restraints are often used for patients undergoing mechanical ventilation to protect important medical equipment. However, they have adverse physical and psychological effects and could pose ethical hazards. Physical restraint use varies by country, but so far there is little understanding of the frequency of physical restraint use among intensive care unit (ICU) patients in Japan. Read More

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http://dx.doi.org/10.1002/ams2.380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328904PMC
January 2019

Validation of the Prediction of Delirium for Intensive Care model to predict subsyndromal delirium.

Acute Med Surg 2019 Jan 3;6(1):54-59. Epub 2018 Dec 3.

Department of Emergency and Critical Care Medicine Tokyo Medical University Shinjuku-ku Tokyo Japan.

Aim: Subsyndromal delirium is associated with prolonged intensive care unit stays, and prolonged mechanical ventilation requirements. The Prediction of Delirium for Intensive Care (PRE-DELIRIC) model can predict delirium. This study was designed to verify if it can also predict development of subsyndromal delirium. Read More

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http://dx.doi.org/10.1002/ams2.378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328902PMC
January 2019

Death or Damnation: Surrogacy and Religious Beliefs.

Am J Hosp Palliat Care 2019 Jan 16:1049909118823189. Epub 2019 Jan 16.

5 St. Luke's Rehabilitation Institute, Spokane, WA, USA.

MC is a 42-year-old female who was in a motor vehicle accident and suffered multiple contusions as well as a fracture of the left femur, pelvic ramus, and left orbit. Due to contusion of the brain, MC has been comatose for over a week and is on mechanical ventilation to protect her airway. There is no written declaration of surrogacy. Read More

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http://dx.doi.org/10.1177/1049909118823189DOI Listing
January 2019

COMPARISON OF GLASGOW COMA SCALE AND FULL OUTLINE OF UNRESPONSIVENESS (FOUR) SCORE: A PROSPECTIVE STUDY.

Turk Neurosurg 2018 Oct 12. Epub 2018 Oct 12.

University of Selcuk School of Medicine.

Aim: Scoring systems are often used in intensive care settings to assess level of consciousness. The purpose of the present study was to assess reliability by comparing the Full Outline of Unresponsiveness (FOUR) scores and Glasgow Coma Scale (GCS) values assigned by specialists from two different fields to patients in the Anesthesiology and Reanimation and Neurosurgery intensive care units.

Material And Methods: This study was conducted between March 2017 and June 2017 at Selçuk University Faculty of Medicine, Departments of Anesthesiology and Reanimation and Neurosurgery. Read More

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http://dx.doi.org/10.5137/1019-5149.JTN.24175-18.2DOI Listing
October 2018

Postoperative acute kidney injury in lung transplant recipients.

Interact Cardiovasc Thorac Surg 2019 Jan 10. Epub 2019 Jan 10.

Respiratory Diseases and Lung Transplantation Unit, University Hospital of Siena (AOUS), Siena, Italy.

Objectives: Acute kidney injury (AKI) is a common postoperative complication after lung transplantation. The aim of the present study was to evaluate the incidence of AKI in lung transplant patients and its effect on patients and graft outcome in relation to degree of severity.

Methods: Data from 135 patients who underwent lung transplant in the same Italian institution were recorded retrospectively and analysed (69 unilateral and 66 bilateral lung transplants, age 51. Read More

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http://dx.doi.org/10.1093/icvts/ivy355DOI Listing
January 2019

Improving Nonvocal Critical Care Patients' Ease of Communication Using a Modified SPEACS-2 Program.

J Healthc Qual 2019 Jan 3. Epub 2019 Jan 3.

Objective: To evaluate the feasibility and impact of implementing the "study of patient-nurse effectiveness with assisted communication strategies-2" (SPEACS-2); a program to facilitate communication with nonvocal patients.

Study Design: The plan-do-study-act quality improvement methodology guided the implementation of a modified SPEACS-2 program within a pre and posttest design. The Ease of Communication Scale (ECS) measured patients' communication difficulty, and care processes measured the program's success. Read More

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http://dx.doi.org/10.1097/JHQ.0000000000000163DOI Listing
January 2019

Unusual Sequence of Events in a Case of Takotsubo Syndrome.

Case Rep Cardiol 2018 13;2018:5498052. Epub 2018 Dec 13.

Department of Cardiology, Maimonides Medical Center, Brooklyn, NY 11219, USA.

A 73-year-old female with multiple comorbidities including coronary artery disease was admitted for an elective PCI of a lesion detected in the RCA. On the day of the planned PCI, shortly after right femoral artery cannulation, the patient developed a sudden complete heart block requiring the administration atropine and insertion of a temporary pacemaker. Concomitantly, the patient developed acute pulmonary edema, hypotension, and hypoxia requiring intubation for mechanical ventilation. Read More

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http://dx.doi.org/10.1155/2018/5498052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311793PMC
December 2018

Ministernotomy or sternotomy in isolated aortic valve replacement? Early results.

Kardiochir Torakochirurgia Pol 2018 Dec 31;15(4):213-218. Epub 2018 Dec 31.

Department of Cardiovascular Surgery and Transplantology, Jagiellonian University, John Paul II Hospital, Krakow, Poland.

Introduction: Aortic valve replacement (AVR) is the gold standard in treating symptomatic aortic valve defects. To improve the healing process and limit the trauma, the minimally invasive approach was introduced.

Aim: To compare the peri- and post-operative results of aortic valve replacement performed via conventional full sternotomy (con-AVR) and of AVR performed via partial upper sternotomy (mini-AVR). Read More

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http://dx.doi.org/10.5114/kitp.2018.80916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329886PMC
December 2018

Management of Acute Respiratory Failure Due to Community-Acquired Pneumonia: A Systematic Review.

Med Sci (Basel) 2019 Jan 14;7(1). Epub 2019 Jan 14.

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Internal Medicine Department, Respiratory unit and Adult Cystic Fibrosis Center, 20122 Milan, Italy.

Community-acquired pneumonia (CAP) is a leading cause of mortality worldwide. CAP mortality is driven by the development of sepsis and acute respiratory failure (ARF). We performed a systematic review of the available English literature published in the period 1 January 1997 to 31 August 2017 and focused on ARF in CAP. Read More

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http://dx.doi.org/10.3390/medsci7010010DOI Listing
January 2019

[A CASE OF PULMONARY FLARE-UP TUBERCULOSIS WITH AN ESOPHAGO-BRONCHIAL FISTULAS AFTER CHEMORADIOTHERAPY FOR ESOPHAGEAL CANCER].

Kekkaku 2017 Mar;92(3):389-393

We present a case of a 59-year-old man with pulmonary tuberculosis and esophago-bronchial fistulas after chemoradiotherapy (CRT) for esophageal cancer. A lung nodule was detected in the right upper lobe and diagnosed as an inactive old inflammatory tumor by several examinations, including bronchoscopy. He was admitted to our hospital because of dysphagia 3 months later. Read More

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March 2017
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Trends in Use of Daily Chest Radiographs Among US Adults Receiving Mechanical Ventilation.

JAMA Netw Open 2018 Aug 3;1(4):e181119. Epub 2018 Aug 3.

Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada.

Importance: Guidelines from December 2011 recommended against obtaining daily chest radiographs (CXRs) for patients requiring mechanical ventilation (MV). Daily CXR use for patients receiving MV in US hospitals is unknown and, if high, may represent an opportunity to reduce low-value care and unnecessary radiation.

Objectives: To determine frequency of daily CXR use for US patients receiving MV, assess variability across hospitals, and evaluate whether use has decreased over time. Read More

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http://dx.doi.org/10.1001/jamanetworkopen.2018.1119DOI Listing

Respiratory Morbidity in Late Preterm and Term Babies Born by Elective Caesarean section.

J Obstet Gynaecol Can 2019 Jan 12. Epub 2019 Jan 12.

Department of Obstetrics and Gynaecology. Division of Maternal Fetal Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON. Electronic address:

Objective: This study sought to determine the incidence and severity of respiratory morbidity among late preterm and term babies born by elective Caesarean section (CS) in London, Ontario.

Methods: A retrospective chart review was conducted of all elective CSs performed at or beyond 36+0 weeks gestation from June 2010 to June 2014 at London Health Sciences Centre and St. Joseph's Health Care (Canadian Task Force Classification II-2). Read More

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http://dx.doi.org/10.1016/j.jogc.2018.11.002DOI Listing
January 2019
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Venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review and meta-analysis.

Lancet Respir Med 2019 Jan 11. Epub 2019 Jan 11.

Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada; University Health Network and Sinai Health System, Toronto, ON Canada.

Background: Use of extracorporeal membrane oxygenation (ECMO) in adults with severe acute respiratory distress syndrome has increased in the past 10 years. However, the efficacy of venovenous ECMO in people with acute respiratory distress syndrome is uncertain according to the most recent data. We aimed to estimate the effect of venovenous ECMO on mortality from acute respiratory distress syndrome. Read More

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http://dx.doi.org/10.1016/S2213-2600(18)30452-1DOI Listing
January 2019

Chest physiotherapy for the prevention of ventilator-associated pneumonia: A meta-analysis.

Am J Infect Control 2019 Jan 11. Epub 2019 Jan 11.

Joint Programme of Nanchang University of London, Nanchang University, Nanchang, Jiangxi, China.

Background: Ventilator-associated pneumonia (VAP) remains a frequent and severe complication in mechanically ventilated patients. We undertook a meta-analysis to evaluate the efficacy of chest physiotherapy (CPT) for the prevention of VAP.

Methods: A systematic literature search of PubMed and Embase databases were searched up until November 25, 2018 for published studies of mechanically ventilated patients comparing CPT with controls and reporting on the occurrence of VAP. Read More

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http://dx.doi.org/10.1016/j.ajic.2018.12.015DOI Listing
January 2019

Sustained inflations during delivery suite stabilisation in prematurely-born infants - A randomised trial.

Early Hum Dev 2019 Jan 11;130:17-21. Epub 2019 Jan 11.

MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, Kings College London, London, United Kingdom; Women and Children's Health, School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, United Kingdom; NIHR Biomedical Research Centre at Guy's and St Thomas' NHS Foundation Trust and King's College London, United Kingdom. Electronic address:

Background: Sustained inflations at initial stabilisation in the delivery suite may reduce the need for intubation and result in a shorter duration of initial ventilation, but have not been compared to routine UK practice.

Aims: To compare the early efficacy of sustained inflation during stabilisation after delivery to UK practice.

Study Design: A randomised trial was performed of a fifteen second sustained inflation compared to five inflations lasting 2 to 3 s, each intervention could be repeated once if no chest rise was apparent. Read More

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http://dx.doi.org/10.1016/j.earlhumdev.2019.01.005DOI Listing
January 2019

Poisoning with malicious or criminal intent: characteristics and outcome of patients presenting for emergency care.

Clin Toxicol (Phila) 2019 Jan 14:1-4. Epub 2019 Jan 14.

a Division of Pediatric Emergency Medicine , Hospital for Sick Children , Toronto , ON , Canada.

Background: Poisoning is the leading cause of injury-related death in the USA. Poisoning with malicious or criminal intent is uncommon, and poorly characterized.

Objectives: To explore substances, patients' demographics, clinical presentation, management and outcome in victims of malicious poisoning in the USA. Read More

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https://www.tandfonline.com/doi/full/10.1080/15563650.2018.1
Publisher Site
http://dx.doi.org/10.1080/15563650.2018.1546009DOI Listing
January 2019
5 Reads

Comparison of outcomes and costs between adult diabetic ketoacidosis patients admitted to the ICU and step-down unit.

J Crit Care 2018 Dec 25;50:257-261. Epub 2018 Dec 25.

Division of Critical Care, Department of Medicine, University of Ottawa, Ottawa, ON, Canada; Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada; Division of Palliative Care, Department of Medicine, University of Ottawa, Ottawa, ON, Canada; Institut du Savoir Montfort, Ottawa, ON, Canada.

Purpose: There is wide variation in the utilization of Intensive Care Unit (ICU) beds for treatment and monitoring of adult patients with Diabetic Ketoacidosis (DKA). We sought to compare the outcomes and hospital costs of adult DKA patients admitted to ICUs as compared to those admitted to step-down units.

Materials And Methods: We included consecutive adult patients from two hospitals with a diagnosis of DKA. Read More

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http://dx.doi.org/10.1016/j.jcrc.2018.12.014DOI Listing
December 2018

An Individualized, Interactive Intervention Promotes Terminally Ill Cancer Patients' Prognostic Awareness and Reduces Cardiopulmonary Resuscitation Received in the Last Month of Life: Secondary Analysis of a Randomized Clinical Trial.

J Pain Symptom Manage 2019 Jan 9. Epub 2019 Jan 9.

School of Nursing, Medical College, Chang Gung University, Department of Nursing, Chang Gung Memorial Hospital at Kaohsiung, and Division of Hematology-Oncology, Chang Gung Memorial Hospital at Linkou, 259 Wen-Hwa 1st Road, Kwei-Shan, Tao-Yuan, Taiwan, 333, R.O.C. Electronic address:

Context/objective: Half of advanced cancer patients do not have accurate prognostic awareness (PA). However, few randomized clinical trials (RCTs) have focused on facilitating patients' PA to reduce their life-sustaining treatments (LSTs) at end of life (EOL). To address these issues, we conducted a double-blinded RCT on terminally ill cancer patients. Read More

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http://dx.doi.org/10.1016/j.jpainsymman.2019.01.002DOI Listing
January 2019

Autologous hematopoietic stem cell transplantation in a patient with refractory seropositive myasthenia gravis: A case report.

Neuromuscul Disord 2018 Nov 25. Epub 2018 Nov 25.

Department of Neurology, Clinica FOSCAL, Bucaramanga, Colombia; Division of Neurology, Department of Internal Medicine, School of Medicine, Universidad Autonoma de Bucaramanga, Bucaramanga, Colombia. Electronic address:

Myasthenia gravis is a neuromuscular autoimmune disease characterized by fatigable weakness of skeletal muscles that results from an antibody-mediated immunological attack directed at acetylcholine postsynaptic receptors. Autologous hematopoietic stem cell transplantation is considered as a treatment option in refractory cases of myasthenia gravis. A 56-year-old Colombian male presented with six-months of progressive hoarseness and dysphagia, with a positive repetitive stimulation test suggestive of end plate neuromuscular disease. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09608966183053
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http://dx.doi.org/10.1016/j.nmd.2018.11.008DOI Listing
November 2018
1 Read

Four-oil intravenous lipid emulsion effect on plasma fatty acid composition, inflammatory markers and clinical outcomes in acutely ill patients: A randomised control trial (Foil fact).

Clin Nutr 2018 Dec 13. Epub 2018 Dec 13.

Division of Human Nutrition, Faculty of Medicine and Health Sciences, Stellenbosch University, Stellenbosch, South Africa.

Background And Aims: Data in critically ill patients on the effect of intravenous lipid emulsions (LEs), containing omega-3 polyunsaturated fatty acids (PUFAs), in parenteral nutrition (PN) are scarce and conflicting. This study compared the effects of a four-oil LE (30% soybean oil, 30% medium-chain triglycerides, 25% olive oil and 15% fish oil (FO)) (SMOFlipid®) to those of a 100% soybean oil-based LE in critically ill adult intensive care unit (ICU) patients.

Methods: In this double-blind, randomised study, patients (n = 75) predicted to need PN for more than 5 days were randomised to receive either a four-oil LE (Study Group (SG)) or a 100% soybean oil LE (Control Group (CG)). Read More

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http://dx.doi.org/10.1016/j.clnu.2018.12.010DOI Listing
December 2018

The ketogenic diet for super-refractory status epilepticus patients in intensive care units.

Brain Dev 2019 Jan 9. Epub 2019 Jan 9.

Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University, School of Medicine, Seoul, Republic of Korea. Electronic address:

Objectives: Super-refractory status epilepticus (SRSE) is one of the most challenging issues in intensive care units (ICUs) in that it is associated with high morbidity and mortality. Although the ketogenic diet (KD) has been reported to be effective in treating of SRSE, the use of the diet as therapy can be complicated by concomitant medical problems specific to critically ill patients. In this study, we aimed to describe our experience of the KD for SRSE patients in ICUs. Read More

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http://dx.doi.org/10.1016/j.braindev.2018.12.007DOI Listing
January 2019

Infant burns: A single institution retrospective review.

Burns 2019 Jan 8. Epub 2019 Jan 8.

Department of Paediatric Surgery, Red Cross War Memorial Children's Hospital and Faculty of Health Sciences, University of Cape Town, South Africa.

Thermal injuries amongst infants are common and a cause of significant mortality and morbidity in South Africa. This has been attributed to the lack of an enabling environment (poverty-related lack of safe living conditions) and the cognitive and physical developmental immaturity of infants, who depend on their surroundings and adults to keep them safe. This is a retrospective observational study of 548 infant admissions over 48 months. Read More

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http://dx.doi.org/10.1016/j.burns.2018.11.005DOI Listing
January 2019

Pre-hospital mechanical ventilation in septic shock patients.

Am J Emerg Med 2019 Jan 7. Epub 2019 Jan 7.

Department of Anesthesia & Intensive Care Unit, SAMU, Hôpital Necker - Enfants Malades, 149 rue de Sèvres, University Paris Descartes, 75015 Paris, France.

Background: Mechanical ventilation can cause deleterious effects on the lung and thus alter patient's prognosis. The aim of this study was to describe the characteristics of prehospital mechanical ventilation in patients with septic shock requiring mechanical ventilation in the prehospital setting.

Methods: Patients with septic shock subjected to pre-hospital intubation and mechanical ventilation by a mobile intensive care unit were consecutively included and retrospectively analysed. Read More

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http://dx.doi.org/10.1016/j.ajem.2018.12.047DOI Listing
January 2019

[The tracheo-team in the management of intracranic pressure during a dilatative tracheostomy in severe head trauma: the impact of a checklist].

Assist Inferm Ric 2018 Oct-Dec;37(4):189-195

. The tracheo-team in the management of intracranic pressure during a dilatative tracheostomy in severe head trauma: the impact of a checklist.

Introduction: Percutaneous dilatative tracheostomy (PDT) is a common technique in neurosurgical intensive care. Read More

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http://dx.doi.org/10.1702/3080.30723DOI Listing
January 2019

[Incidence and risk factors associated with the development of pressure ulcers in an Italian general intensive care unit].

Assist Inferm Ric 2018 Oct-Dec;37(4):181-188

. Incidence and risk factors associated with the development of pressure ulcers in an Italian general intensive care unit.

Introduction: Pressure ulcers (PU) represent one of the most frequent adverse event in intensive care units (ICU). Read More

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http://dx.doi.org/10.1702/3080.30722DOI Listing
January 2019

Impact of chest radiograph appearance-based definition of bronchopulmonary dysplasia.

Pediatr Int 2019 Jan 13. Epub 2019 Jan 13.

Department of Pediatrics, Akita University Graduate School of Medicine.

Objective: The Bubbly/cystic appearance on chest radiograph is an important factor in the severe type of bronchopulmonary dysplasia (BPD) in Japan. Our objective is to determine the perinatal characteristics and neonatal complications of the bubbly/cystic+ group in extremely preterm infants with BPD by oxygen dependency at day28 after birth (BPD28).

Study Design: This was a multicenter retrospective cohort study of population data from infants (birth weight, <1,500 g) enrolled in the Neonatal Research Network of Japan. Read More

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http://dx.doi.org/10.1111/ped.13786DOI Listing
January 2019

Congenital diaphragmatic hernia sacs: prenatal imaging and associated postnatal outcomes.

Pediatr Radiol 2019 Jan 11. Epub 2019 Jan 11.

Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Background: The presence of a hernia sac in congenital diaphragmatic hernia (CDH) has been reported to be associated with higher lung volumes and better postnatal outcomes.

Objective: To compare prenatal imaging (ultrasound and MRI) prognostic measurements and postnatal outcomes of CDH with and without hernia sac.

Materials And Methods: We performed database searches from January 2008 to March 2017 for surgically proven cases of CDH with and without hernia sac. Read More

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http://dx.doi.org/10.1007/s00247-018-04334-9DOI Listing
January 2019

Health-related quality of life as predictor for mortality in patients treated with long-term mechanical ventilation.

BMC Pulm Med 2019 Jan 11;19(1):13. Epub 2019 Jan 11.

Department of Global Public Health and Primary Care, University in Bergen, Kalfarveien 31, 5018, Bergen, Norway.

Background: The Severe Respiratory Insufficiency (SRI) questionnaire is a specific measure of health-related quality of life (HRQoL) in patients treated with long-term mechanical ventilation (LTMV). The aim of the present study was to examine whether SRI sum scores and related subscales are associated with mortality in LTMV patients.

Methods: The study included 112 LTMV patients (non-invasive and invasive) from the Norwegian LTMV registry in Western Norway from 2008 with follow-up in August 2014. Read More

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https://bmcpulmmed.biomedcentral.com/articles/10.1186/s12890
Publisher Site
http://dx.doi.org/10.1186/s12890-018-0768-4DOI Listing
January 2019
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Evaluations of Morphine and Fentanyl for Mechanically Ventilated Patients With Respiratory Disorders in Intensive Care: A Systematic Review of Methodological Trends and Reporting Quality.

Value Health Reg Issues 2019 Jan 8;19:7-25. Epub 2019 Jan 8.

College of Pharmacy, Qatar University, Doha, Qatar. Electronic address:

Background: Mechanically ventilated patients with respiratory disorders may require sedatives, such as opioids.

Objectives: To define methodological trends, gaps, and the reporting quality of the comparative clinical and economic evaluations of fentanyl and morphine in ventilated patients in the intensive care unit.

Methods: We conducted a literature review of the MEDLINE, Embase, OVID, ScienceDirect, Springer Link, and EconLit databases, comparing studies in the management of ventilated patients with respiratory disorders in the intensive care unit using either fentanyl or morphine, or both. Read More

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http://dx.doi.org/10.1016/j.vhri.2018.11.001DOI Listing
January 2019

Severe Patient Injury Associated with Mechanical Ventilators: A "Never Event".

Authors:
Karen B Domino

Anaesth Crit Care Pain Med 2019 Jan 8. Epub 2019 Jan 8.

Professor and Vice Chair for Clinical Research, Department of Anesthesiology & Pain Medicine, University of Washington School of Medicine, Seattle, WA 98199, Washington. Electronic address:

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http://dx.doi.org/10.1016/j.accpm.2019.01.001DOI Listing
January 2019

Evaluation of a Symptom-triggered Protocol for Alcohol Withdrawal for Use in the Emergency Department, General Medical Wards, and Intensive Care Unit.

J Psychiatr Pract 2019 Jan;25(1):63-70

RICHMAN: Department of Pulmonary and Critical Care Medicine, Colorado Permanente Medical Group, Kaiser Permanente, Lafayette, CO GARCIA: Department of Pulmonary and Critical Care Medicine, The Harvard-Brigham and Women's Hospital, Boston, MA BOUCHARD: Department of Emergency Medicine, Lenox Health Greenwich Village, Northwell Health, New York, NY MUSKIN: Department of Psychiatry, New York-Presbyterian Hospital-Columbia University Medicine Center, New York, NY DZIERBA: Department of Pharmacy, New York-Presbyterian Hospital-Columbia University Medicine Center, New York, NY.

Background: Alcohol withdrawal is common in hospitalized patients and symptom-triggered guidelines have been shown to reduce treatment duration, length of stay, and need for mechanical ventilation.

Objectives: To assess the feasibility of incorporating symptom-triggered alcohol withdrawal guidelines early in the hospital course and to evaluate outcomes of patients before and after implementation of the guidelines.

Methods: This was a retrospective pre-post study of adult patients admitted from the emergency department to an urban, academic, tertiary care center. Read More

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http://dx.doi.org/10.1097/PRA.0000000000000354DOI Listing
January 2019

Cross-cultural adaptation, validity and reliability of the Turkish version of Revised Nonverbal Pain Scale.

Agri 2019 Jan;31(1):15-22

Department of General Surgery Intensive Care, Adana City Hospital, Adana, Turkey.

Objectives: In this study, we aimed to adapt the Revised Nonverbal Pain Scale (NVPS-R) into Turkish, and to test reliability and validity of the scale.

Methods: A total of 74 patients who were admitted to eight intensive care units in two hospitals between May 2016 and August 2017 were included in this study. All patients were over 18 years old, mechanically ventilated, and sedated. Read More

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http://dx.doi.org/10.5505/agri.2018.25349DOI Listing
January 2019

On-table extubation in neonates undergoing anoplasty: an experience of anesthetic management on the concept of fast-tracking anesthesia: A pilot study.

Medicine (Baltimore) 2019 Jan;98(2):e14098

Department of Anesthesiology, Sichuan University West China Hospital.

Fast-track anesthesia (FTA) is difficult to achieve in neonates due to immature organ function and high rates of perioperative events. As a high-risk population, neonates require prolonged postoperative mechanical ventilation, which may lead to contradictions in cases where neonatal intensive care unit resources and ventilator facilities are limited. The choice of anesthesia strategy and anesthetic can help achieve rapid postoperative rehabilitation and save hospitalization costs. Read More

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http://dx.doi.org/10.1097/MD.0000000000014098DOI Listing
January 2019
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Effects of theophylline therapy on respiratory muscle strength in patients with prolonged mechanical ventilation: A retrospective cohort study.

Medicine (Baltimore) 2019 Jan;98(2):e13982

Department of Thoracic Medicine, Chang-Gung Memorial Hospital.

Mechanical ventilation may cause diaphragm weakness an effect termed ventilator-induced diaphragm dysfunction (VIDD). The prevalence of VIDD among patients receiving mechanical ventilation is very high, with the degree of diaphragmatic atrophy being associated with the length of mechanical ventilation. Theophylline is known to increase diaphragmatic contractility and reduce fatigue, so in this study, we evaluated the effect of theophylline in patients with prolonged mechanical ventilation. Read More

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http://dx.doi.org/10.1097/MD.0000000000013982DOI Listing
January 2019

Rates of Mechanical Ventilation for Patients With Dementia in Ontario: A Population-Based Cohort Study.

Anesth Analg 2019 Jan 8. Epub 2019 Jan 8.

From the Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

The number of elderly patients with dementia receiving invasive mechanical ventilation is increasing over time in the United States, while the balance of potential benefits and harms of intensive care interventions in this population is unclear. In this report, we describe trends in use of invasive mechanical ventilation in elderly individuals with and without dementia in Ontario, Canada, and provide projections of the use of invasive mechanical ventilation through 2025. We show that rates of invasive mechanical ventilation for elderly patients with dementia are increasing faster than for the rest of the elderly (nondementia) population. Read More

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http://dx.doi.org/10.1213/ANE.0000000000004003DOI Listing
January 2019

Outcome Of Use Of Nasal Continuous Positive Airway Pressure Through Infant Flow Drivers In Neonates With Respiratory Distress In A Tertiary Care Hospital In Pakistan.

J Ayub Med Coll Abbottabad 2018 Oct-Dec;30(4):511-555

Iqbal Memorial Teaching Hospital/Khawaja Muhammad Safdar Medical College Sialkot, Pakistan.

Background: Nasal continuous positive pressure has been used for management of respiratory distress in neonates in various conditions as a primary modality. Objective of the study is to evaluate the frequency of improved outcome and complications of use of nasal CPAP through infant flow drivers in neonates with respiratory distress. The study was conducted from 2nd April 2017 to 2nd October 2017 in neonatal intensive care unit of Allama Iqbal Memorial Teaching Hospital Sialkot. Read More

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January 2019
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A conceivable mechanism of harm in a stretched "teen lung".

Crit Care 2019 Jan 10;23(1). Epub 2019 Jan 10.

Centre for Human and Applied Physiological Sciences, King's College, London, UK.

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https://ccforum.biomedcentral.com/articles/10.1186/s13054-01
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http://dx.doi.org/10.1186/s13054-018-2284-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327457PMC
January 2019
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Conservative Fluid Management After Sepsis Resuscitation: A Pilot Randomized Trial.

J Intensive Care Med 2019 Jan 10:885066618823183. Epub 2019 Jan 10.

1 Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.

Rationale:: The feasibility and clinical outcomes of conservative fluid management after sepsis resuscitation remain unknown.

Objectives:: To evaluate the effect of a conservative fluid management protocol on fluid balance and intensive care unit (ICU)-free days among patients with sepsis.

Methods:: In a single-center phase II/III randomized trial, we enrolled adults with suspected infection, ≥2 systemic inflammatory response syndrome criteria, and either shock (mean arterial pressure <60 mm Hg or vasopressors) or respiratory insufficiency (mechanical ventilation or oxygen saturation <97% and fraction of inspired oxygen ≥0. Read More

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http://dx.doi.org/10.1177/0885066618823183DOI Listing
January 2019

[Clinical characteristics and risk factors of very low birth weight and extremely low birth weight infants with bronchopulmonary dysplasia: multicenter retrospective analysis].

Authors:

Zhonghua Er Ke Za Zhi 2019 Jan;57(1):33-39

To analyze clinical characteristics and risk factors of very low birth weight and extremely low birth weight infants with bronchopulmonary dysplasia (BPD). A retrospective epidemiological study was performed in 768 neonates (376 males) with birth weights<1 500 g and gestational age ≤ 34 weeks who survived ≥28 days. Clinical data were obtained from the multi-center clinical database of neonatal intensive care units (NICU) in 19 hospitals of Jiangsu Province between January 1, 2017 and December 31, 2017. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0578-1310.2019.01.009DOI Listing
January 2019

Ventilatory support after extubation in critically ill patients.

Lancet Respir Med 2018 Dec;6(12):948-962

University Department of Medical, Oral and Biotechnological Sciences, Gabriele d'Annunzio University of Chieti-Pescara, Chieti, Italy; Clinical Department of Anaesthesiology and Intensive Care Medicine, SS. Annunziata Hospital, Chieti, Italy.

The periextubation period represents a crucial moment in the management of critically ill patients. Extubation failure, defined as the need for reintubation within 2-7 days after a planned extubation, is associated with prolonged mechanical ventilation, increased incidence of ventilator-associated pneumonia, longer intensive care unit and hospital stays, and increased mortality. Conventional oxygen therapy is commonly used after extubation. Read More

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http://dx.doi.org/10.1016/S2213-2600(18)30375-8DOI Listing
December 2018

Observing Pneumothoraces: The 35 Millimeter Rule Is Safe for Both Blunt and Penetrating Chest Trauma.

J Trauma Acute Care Surg 2019 Jan 8. Epub 2019 Jan 8.

Division of Trauma, Critical Care, and Acute Care Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI.

Introduction: As more pneumothoraxes (PTX) are being identified on chest computed tomography (CT), the empiric trigger for tube thoracostomy (TT) versus observation remains unclear. We hypothesized that PTX measuring ≤35 mm on chest CT can be safely observed in both penetrating and blunt trauma mechanisms.

Methods: A retrospective review was conducted of all patients diagnosed with PTX by chest CT between January 2011 and December 2016. Read More

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http://dx.doi.org/10.1097/TA.0000000000002192DOI Listing
January 2019

The bioimpedance spectroscopy as useful tool for measuring the fluid excess and fluid management in severe polytrauma patients.

Physiol Res 2019 Jan 10. Epub 2019 Jan 10.

Faculty of Pharmacy, Educational and Research Center of Charles University, Hradec Kralove, Czech Republic.

Although the fluid therapy plays a fundamental role in the management of polytrauma patients (PP), a tool which could determine it appropriately is still lacking. The aim of this study was to evaluate the application of a bioimpedance spectroscopy (BIS) for body fluids volume and distribution monitoring in these patients. This prospective, observational study was performed on 25 severe PP and 25 healthy subjects. Read More

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January 2019