21,285 results match your criteria Ventilation Management


Predictors for long-term mortality in COPD patients requiring non-invasive positive pressure ventilation for the treatment of acute respiratory failure.

Clin Respir J 2020 Aug 11. Epub 2020 Aug 11.

Department of Respiratory Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.

Introduction: The effectiveness of non-invasive mechanical ventilation (NIV) in the management of COPD patients suffering from acute respiratory failure (ARF) as a consequence of exacerbation of the disease, is well-established. However, data on long-term outcomes and their predictors, including the individual response to NIV, are scarce.

Objectives: To investigate predictors for short- and long-term mortality in this study population. Read More

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http://dx.doi.org/10.1111/crj.13251DOI Listing

Discharge Practices for Children with Home Mechanical Ventilation Across the United States: Key Informant Perspectives.

Ann Am Thorac Soc 2020 Aug 11. Epub 2020 Aug 11.

Northwestern University Feinberg School of Medicine, 12244, Division of Pediatric Critical Care Medicine, Chicago, Illinois, United States.

Rationale: In 2016 the ATS released Clinical Practice Guidelines for Pediatric Chronic Home Invasive Ventilation pertaining to discharge practices and subsequent management for patients with invasive ventilation using a tracheostomy. It is not known to what extent current US practices adhere to these recommendations.

Objective: Hospital discharge practices and home health services are not standardized for children with invasive home mechanical ventilation (HMV). Read More

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http://dx.doi.org/10.1513/AnnalsATS.201912-875OCDOI Listing

Intratracheal administration of budesonide with surfactant in very low birth weight infants to prevent bronchopulmonary dysplasia.

Turk J Pediatr 2020 ;62(4):551-559

Department of Pediatrics, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.

Background And Objectives: Respiratory distress syndrome (RDS) is a major cause of early postnatal death in preterm infants. Bronchopulmonary dysplasia (BPD) is one of the most fatal chronic respiratory complications of preterm infants after management of RDS. Anti-inflammatory therapy with corticosteroid is one of the effective treatments to prevent BPD. Read More

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http://dx.doi.org/10.24953/turkjped.2020.04.004DOI Listing
January 2020

Indoor Emissions of Total and Fluorescent Supermicron Particles during HOMEChem.

Indoor Air 2020 Aug 10. Epub 2020 Aug 10.

Department of Environmental Science, Policy, and Management, University of California, Berkeley, CA, USA.

Inhalation of particulate matter is associated with adverse health outcomes. The fluorescent portion of supermicron particulate matter has been used as a proxy for bioaerosols.The sources and emission rates of fluorescent particles in residential environments are not wellunderstood. Read More

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http://dx.doi.org/10.1111/ina.12731DOI Listing

Does Intolerance of Single-Lung Ventilation Preclude Robotic Off-Pump Totally Endoscopic Coronary Bypass Surgery?

Innovations (Phila) 2020 Aug 10:1556984520940462. Epub 2020 Aug 10.

21727 Department of Anesthesia, University of Chicago Medicine, IL, USA.

Objective: Robotic off-pump totally endoscopic coronary artery bypass (TECAB) usually requires isolated single (right) lung ventilation to adequately expose the surgical site. However, in some patients, persistent oxygen desaturation may occur and conversion to cardiopulmonary bypass (CPB) or sternotomy may be necessary. We reviewed the characteristics and clinical outcomes in patients who did not tolerate single-lung ventilation during TECAB surgery. Read More

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http://dx.doi.org/10.1177/1556984520940462DOI Listing

Recurrent massive pulmonary emboli in a critically ill patient with COVID-19.

Anaesth Rep 2020 Jul-Dec;8(2):e12059. Epub 2020 Aug 1.

Adult Intensive Care Unit Oxford University Hospitals NHS Foundation Trust Oxford UK.

We report the haematological management of a critically ill patient with coronavirus disease 2019 (COVID-19), with recurrent massive pulmonary emboli. A previous healthy 56-year-old man presented to the emergency department with severe hypoxaemic respiratory failure due to suspected COVID-19. He required invasive mechanical ventilation and transfer to the intensive care unit for increasing ventilatory requirements and cardiovascular instability. Read More

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http://dx.doi.org/10.1002/anr3.12059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395430PMC

COVID-19 Infection in Kidney Transplant Recipients: A Single-Center Case Series of 22 Cases From Belgium.

Kidney Med 2020 Jul-Aug;2(4):459-466. Epub 2020 Jun 15.

Division of Nephrology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium.

Rationale & Objective: The world is facing a global pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although kidney transplant recipients are at increased risk for viral infections, the impact of their chronic immunosuppressed status on the risk for acquiring coronavirus disease 2019 (COVID-19) and disease severity is unknown.

Study Design: All cases of COVID-19 infection in our cohort of kidney transplant recipients were prospectively monitored. Read More

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http://dx.doi.org/10.1016/j.xkme.2020.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295531PMC

Successful use of inhaled epoprostenol as rescue therapy for pediatric ARDS.

Respir Med Case Rep 2020 10;31:101148. Epub 2020 Jul 10.

Division of Pediatric Critical Care, Kansas University Medical Center, Kansas City, KS, USA.

Severe pediatric ARDS remains a significant challenge for clinicians, and management strategies are essentially limited to lung protective ventilation strategies, and adjunct approaches such as prone positioning, steroids, surfactant, and inhaled nitric oxide in unique situations. Inhaled nitric oxide produces pulmonary vasodilation in ventilated regions of the lung, shunting blood away from poorly ventilated areas and thus optimizing the ventilation perfusion ratio. A subset of patients with ARDS are known to be non-responders to nitric oxide, and selective pulmonary vasodilators such as Epoprostenol can be useful as rescue therapy in such cases. Read More

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http://dx.doi.org/10.1016/j.rmcr.2020.101148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394910PMC

Weather the Cytokine Storm: A Report of Successful Management of a Colon Cancer Survivor and a Critically Ill Patient with COVID-19.

Case Rep Oncol 2020 May-Aug;13(2):754-759. Epub 2020 Jun 29.

Division of Hematology/Oncology, Augusta University, Augusta, Georgia, USA.

Patients with novel corona virus infection (COVID-19) can develop acute respiratory failure secondary to acute respiratory distress syndrome. Cytokine storm is suggested as one of underlying mechanisms for the rapid clinical decline. Immunocompromised patients and cancer patients are at particular risk for poor outcomes due to COVID-19 infection. Read More

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http://dx.doi.org/10.1159/000509507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360508PMC

Effectiveness of simulation based teaching of ventilatory management among non-anaesthesiology residents to manage COVID 19 pandemic - A Quasi experimental cross sectional pilot study.

Indian J Anaesth 2020 May 23;64(Suppl 2):S136-S140. Epub 2020 May 23.

Department of Community Medicine, GSL Medical College, Rajahmundry, Andhra Pradesh, India.

Background And Aims: Simulation is one of the important learning tools when it comes to skill acquisition and as a supplemental tool for training in high stake situations like COVID-19. The aim of this study is to meet the global requirements of knowledge on ventilatory management, prepare and to evaluate the effectiveness of the teaching module for non-anesthesiology trainees on COVID-19 patients.

Methods: Quasi experimental cross sectional pilot study was conducted with a sample of twenty-six trainees. Read More

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http://dx.doi.org/10.4103/ija.IJA_452_20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293371PMC

All India difficult airway association (AIDAA) consensus guidelines for airway management in the operating room during the COVID-19 pandemic.

Indian J Anaesth 2020 May 23;64(Suppl 2):S107-S115. Epub 2020 May 23.

Department of Anesthesiology, Critical Care and Pain, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, Maharashtra, India.

Severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) which causes coronavirus disease (COVID-19) is a highly contagious virus. The closed environment of the operation room (OR) with aerosol generating airway management procedures increases the risk of transmission of infection among the anaesthesiologists and other OR personnel. Wearing complete, fluid impermeable personal protective equipment (PPE) for airway related procedures is recommended. Read More

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http://dx.doi.org/10.4103/ija.IJA_498_20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293372PMC

Clinico-demographic profile & hospital outcomes of COVID-19 patients admitted at a tertiary care centre in north India.

Indian J Med Res 2020 Jul 22. Epub 2020 Jul 22.

Department of Hospital Administration, National Cancer Institute, All India Institute of Medical Sciences, Jhajjar, Haryana, India.

Background & Objectives: : In December 2019, a novel coronavirus (SARS-CoV-2) emerged in China and rapidly spread globally including India. The characteristic clinical observations and outcomes of this disease (COVID-19) have been reported from different countries. The present study was aimed to describe the clinico-demographic characteristics and in-hospital outcomes of a group of COVID-19 patients in north India. Read More

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http://dx.doi.org/10.4103/ijmr.IJMR_1788_20DOI Listing

[Evolution of Opinions on Chest Wall Stabilisation and Our Experience].

Acta Chir Orthop Traumatol Cech 2020 ;87(3):155-161

I. chirurgická klinika Fakultní nemocnice Olomouc a Lékařské fakulty Univerzity Palackého v Olomouci.

PURPOSE OF THE STUDY Rib fractures represent one of the most common fractures sustained by 10-40% of all patients with blunt chest trauma, their incidence increases with age. In the current literature, however, new indication criteria continue to emerge. The purpose of this study is to assess the indication criteria, the timing of surgery and the use of individual plates in dependence on fracture location in our patients after the chest wall stabilisation in a retrospective analysis. Read More

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January 2020

Corticosteroids in the Management of Pregnant Patients With Coronavirus Disease (COVID-19).

Obstet Gynecol 2020 Aug 4. Epub 2020 Aug 4.

Division of Maternal-Fetal Medicine, Department of Obstetrics & Gynecology, and the Division of Surgical Critical Care, Department of Anesthesiology, the University of Texas Medical Branch at Galveston, Galveston, Texas; and the Department of Women and Children's Health, School of Life Course Sciences, King's College London, London, United Kingdom.

Recent evidence supports the use of an early, short course of glucocorticoids in patients with COVID-19 who require mechanical ventilation or oxygen support. As the number of coronavirus disease 2019 (COVID-19) cases continues to increase, the number of pregnant women with the disease is very likely to increase as well. Because pregnant women are at increased risk for hospitalization, intensive care unit admission, and mechanical ventilation support, obstetricians will be facing the dilemma of initiating maternal corticosteroid therapy while weighing its potential adverse effects on the fetus (or neonate if the patient is postpartum and breastfeeding). Read More

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http://dx.doi.org/10.1097/AOG.0000000000004103DOI Listing

Natural history of COVID-19 and current knowledge on treatment therapeutic options.

Biomed Pharmacother 2020 Jul 3;129:110493. Epub 2020 Jul 3.

Laboratory of Genetics and Molecular Biology, Department of Biomedicine, Graduate Program in Applied Health Sciences, Special Academic Unit of Health Sciences, Federal University of Jataí-UFJ, BR 364, Km 195, Nº 3800, CEP 75801-615, Jataí, Goiás, Brazil. Electronic address:

Despite intense research there is currently no effective vaccine available against the new severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged in the later 2019 and responsible for the COVID-19 pandemic. This infectious and communicable disease has become one of the major public health challenges in the world. The clinical management of COVID-19 has been limited to infection prevention and control measures associated with supportive care such as supplemental oxygen and mechanical ventilation. Read More

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http://dx.doi.org/10.1016/j.biopha.2020.110493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332915PMC

Stem Cell Therapy for Covid-19: Possibilities and Challenges.

Cell Biol Int 2020 Aug 7. Epub 2020 Aug 7.

Department of Immunobiology, College of Medicine, The University of Arizona, Tucson, USA.

Since its eruption in China, novel coronavirus disease (Covid-19) has been reported in most of the countries and territories (>200) of the world with ~ 18 million confirmed cases (as of August 3, 2020). In most of the countries, Covid-19 upsurge is uncontrolled with a significant mortality rate. Currently no treatment effective for Covid-19 is available in the form of vaccines or antiviral drugs and patients are currently treated symptomatically. Read More

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http://dx.doi.org/10.1002/cbin.11440DOI Listing

Outcome of improved care bundle in acute respiratory failure patients.

Nurs Crit Care 2020 Aug 6. Epub 2020 Aug 6.

Department of Biomedical and Environmental Biology, Kaohsiung Medical University, Kaohsiung, Taiwan.

Background: Prolonged physical immobilization has negative effects on patients on mechanical ventilation (MV).

Aims: To introduce a quality improvement programme with early mobilization on the outcomes of patients on MV in the intensive care unit (ICU). We particularly studied the impact of the ABCDE (daily Awakening, Breathing trial, drug Co-ordination, Delirium survey and treatment, and Early mobilization) bundle on the outcome of MV patients with acute respiratory failure in the ICU. Read More

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http://dx.doi.org/10.1111/nicc.12530DOI Listing

Preparedness and Reorganization of Care for Coronavirus Disease 2019 Patients in a Swiss ICU: Characteristics and Outcomes of 129 Patients.

Crit Care Explor 2020 Aug 29;2(8):e0173. Epub 2020 Jul 29.

Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland.

Objectives: In many countries, large numbers of critically ill patients with coronavirus disease 2019 are admitted to the ICUs within a short period of time, overwhelming usual care capacities. Preparedness and reorganization ahead of the wave to increase ICU surge capacity may be associated with favorable outcome. The purpose of this study was to report our experience in terms of ICU organization and anticipation, as well as reporting patient characteristics, treatment, and outcomes. Read More

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http://dx.doi.org/10.1097/CCE.0000000000000173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392615PMC

Use of an Electronic Feeds Calorie Calculator in the Pediatric Intensive Care Unit.

Pediatr Qual Saf 2020 Jan-Feb;5(1):e249. Epub 2020 Jan 12.

Children's Intensive Care Unit, Department of Pediatric Subspecialties, KK Women's and Children's Hospital, Singapore.

Strategies to improve nutritional management are associated with better outcomes in pediatric intensive care units. We implemented a calorie-based protocol that integrated an electronic feeds calculator and stepwise feeds increment algorithm.

Methods: Using a pretest-posttest design, we compared the effectiveness of the calorie-based protocol with an existing fluid-based protocol in a quality improvement project. Read More

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http://dx.doi.org/10.1097/pq9.0000000000000249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056286PMC
January 2020

Possible association of idiopathic pulmonary hemosiderosis with rheumatoid arthritis: A case report.

Exp Ther Med 2020 Sep 25;20(3):2291-2297. Epub 2020 Jun 25.

Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing 100029, P.R. China.

Idiopathic pulmonary hemosiderosis (IPH) is a rare interstitial lung disease, usually occurring in children or young adults. Although several studies reported on the coexistence of IPH and immune system diseases, the association between these conditions has not been well described. The present study reports on the case of a 21-year-old female patient who presented with bilateral lung abnormalities. Read More

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http://dx.doi.org/10.3892/etm.2020.8938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401859PMC
September 2020

Thrombolysis in severe COVID-19 pneumonia with massive pulmonary embolism.

Am J Emerg Med 2020 Jul 30. Epub 2020 Jul 30.

Critical Care Department, King Saud Medical City, Riyadh, Saudi Arabia; University of South Carolina, School of Medicine, Columbia, SC, USA. Electronic address:

Objective: No guidelines exist for the management of massive pulmonary embolism (PE) in COVID-19. We present a COVID-19 patient with refractory acute respiratory syndrome (ARDS), and life-threatening PE who underwent successful thrombolysis.

Case Presentation: A previously healthy 47 year old male was admitted to our hospital due to severe COVID-19 pneumonia [confirmed by Real-Time-Polymerase-Chain-Reaction (RT-PCR)]. Read More

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http://dx.doi.org/10.1016/j.ajem.2020.07.068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392155PMC

Pathophysiology of current odontogenic maxillary sinusitis and endoscopic sinus surgery preceding dental treatment.

Auris Nasus Larynx 2020 Aug 3. Epub 2020 Aug 3.

Department of Otolaryngology-Head and Neck Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011, Japan.

Objective: The successful management of odontogenic maxillary sinusitis (OMS) involves a combination of medical treatment with dental surgery and/or endoscopic sinus surgery (ESS). However, there is no consensus for the optimal timing of ESS. Although several studies have emphasized dental surgery as the primary treatment modality for OMS, there is recent evidence to suggest that ESS alone may be an effective treatment approach. Read More

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http://dx.doi.org/10.1016/j.anl.2020.07.021DOI Listing

Endotracheal suction interventions in mechanically ventilated children: An integrative review to inform evidence-based practice.

Aust Crit Care 2020 Aug 4. Epub 2020 Aug 4.

Department of Paediatics and Child Health, University of Cape Town, South Africa.

Objective: The objective of this study was to review and critically appraise the evidence for paediatric endotracheal suction interventions.

Data Sources: A systematic search for studies was undertaken in the electronic databases CENTRAL, Medline, EMBASE, and EBSCO CINAHL from 2003.

Study Selection: Included studies assessed suction interventions in children (≤18 ys old) receiving mechanical ventilation. Read More

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http://dx.doi.org/10.1016/j.aucc.2020.05.003DOI Listing

Anesthetic Implications of a Pediatric Patient with Stiff Skin Syndrome: A Case Report.

Paediatr Anaesth 2020 Aug 5. Epub 2020 Aug 5.

University of Texas Southwestern, Department ofAnesthesiology and Pain Management, 5323 Harry Hines Boulevard, Dallas, TX, 75390, USA.

Stiff Skin Syndrome (SSS) is a rare genetic syndrome characterized by rock-hard, indurated skin and joint contractures that worsen with age. Difficulties with mask ventilation should be expected due to the restrictive effect of the skin overlying the chest and abdomen, especially after muscle relaxation. Endotracheal intubation is often challenging, and advanced devices should be immediately available. Read More

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http://dx.doi.org/10.1111/pan.13989DOI Listing

Invasive mechanical ventilation using a bilevel PAP ST device in a healthy swine model.

Sleep Breath 2020 Aug 6. Epub 2020 Aug 6.

Department of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.

Purpose: The Coronavirus Disease 2019 (COVID-19) pandemic may cause an acute shortage of ventilators. Standard noninvasive bilevel positive airway pressure devices with spontaneous and timed respirations (bilevel PAP ST) could provide invasive ventilation but evidence on their effectiveness in this capacity is limited. We sought to evaluate the ability of bilevel PAP ST to effect gas exchange via invasive ventilation in a healthy swine model. Read More

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http://dx.doi.org/10.1007/s11325-020-02141-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406961PMC

Successful management of seven cases of critical COVID-19 with early noninvasive-invasive sequential ventilation algorithm and bundle pharmacotherapy.

Front Med 2020 Aug 6. Epub 2020 Aug 6.

Department of Intensive Care Unit, The Third Affiliated Hospital of Shenzhen University, Shenzhen, 518001, China.

We report the clinical and laboratory findings and successful management of seven patients with critical coronavirus disease 2019 (COVID-19) requiring mechanical ventilation (MV). The patients were diagnosed based on epidemiological history, clinical manifestations, and nucleic acid testing. Upon diagnosis with COVID-19 of critical severity, the patients were admitted to the intensive care unit, where they received early noninvasive-invasive sequential ventilation, early prone positioning, and bundle pharmacotherapy regimen, which consists of antiviral, anti-inflammation, immune-enhancing, and complication-prophylaxis medicines. Read More

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http://dx.doi.org/10.1007/s11684-020-0796-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406958PMC

Is ventilated hospital-acquired pneumonia a worse entity than ventilator-associated pneumonia?

Eur Respir Rev 2020 Sep 4;29(157). Epub 2020 Aug 4.

Dept of Anesthesiology, Intensive Care and Emergency Medicine, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy

Introduction: Nosocomial pneumonia develops after ≥48 h of hospitalisation and is classified as ventilator-associated pneumonia (VAP) and hospital-acquired pneumonia (HAP); the latter may require mechanical ventilation (V-HAP) or not (NV-HAP).

Main Findings: VAP and HAP affect a significant proportion of hospitalised patients and are characterised by poor clinical outcomes. Among them, V-HAP has the greatest 28-day mortality rate followed by VAP and NV-HAP (27. Read More

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http://dx.doi.org/10.1183/16000617.0023-2020DOI Listing
September 2020

Severe tetanus following ulcerated skin cancer: Case report.

Medicine (Baltimore) 2020 Jul;99(31):e21529

Department of Emergency, Shenzhen People's Hospital, The Second Clinical Medical College, Jinan University.

Rationale: Tetanus is usually caused by wound infection with Clostridium tetani after acute injuries. Skin cancer wound is a rarely reported cause of tetani infection. It is difficult to be diagnosed and mistaken for other brain lesions. Read More

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http://dx.doi.org/10.1097/MD.0000000000021529DOI Listing

D-dimer surge and coagulation disorders in COVID-19 related pneumonia patients with cardiac injury: A case series.

Medicine (Baltimore) 2020 Jul;99(31):e21513

Department of Hematology, The First Hospital of Jilin University, Jilin Provincial Hematology Research Institute, National Key Discipline.

Background: Cardiac injury and coagulation disorders have been two increasing concerns in the management of patients with severe coronavirus disease (COVID-19). Coagulation disorders in COVID-19 patients with cardiac injury have not been characterized.

Methods: We analyzed the data of five COVID-19 patients with cardiac injury who had D-dimer surge (defined as a rapid increase in the D-dimer level in 72 h, from <5-21 μg/mL) during hospitalization, which were extracted from a registered retrospective study (ChiCTR2000031301). Read More

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http://dx.doi.org/10.1097/MD.0000000000021513DOI Listing

Inpatient Care during the COVID-19 Pandemic: A Survey of Italian Physicians.

Respiration 2020 Aug 5:1-11. Epub 2020 Aug 5.

Dipartimento di Scienze della Salute, Università degli Studi di Milano, Milan, Italy,

Background: Coronavirus disease 2019 (COVID-19) is a potentially fatal disease that is of great global public health concern.

Objective: We explored the clinical management of inpatients with COVID-19 in Italy.

Methods: A self-administered survey was sent by email to Italian physicians caring for adult patients with COVID-19. Read More

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http://dx.doi.org/10.1159/000509007DOI Listing

Nasogastric administration of lenvatinib solution in a mechanically ventilated patient with rapidly growing anaplastic thyroid cancer.

Endocrinol Diabetes Metab Case Rep 2020 Aug 4;2020. Epub 2020 Aug 4.

Departments of Surgery, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.

Summary: A 54-year-old woman was referred to our hospital with a cervical tumor. CT revealed a cervical tumor extending to the upper mediastinum, tracheal deviation and tumor infiltration in the cervical vessels. She was followed-up because no diagnosis of malignancy was made by cytology. Read More

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http://dx.doi.org/10.1530/EDM-20-0064DOI Listing

Cannabis Vaping-Induced Acute Pulmonary Toxicity: Case Series and Review of Literature.

J Investig Med High Impact Case Rep 2020 Jan-Dec;8:2324709620947267

Adventist Medical Center, Hanford, CA, USA.

The use of cannabis for recreational as well as medicinal use is on the rise recently with more states legalizing it. We conducted a review analysis of the literature published on acute respiratory failure from vaping cannabis oil. We have also summarized the clinical details (age, length of stay, mode of ventilation, common clinical findings, and steroid use) along with common laboratory abnormalities. Read More

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http://dx.doi.org/10.1177/2324709620947267DOI Listing

High flow nasal cannula in COVID-19: a literature review.

Tuberk Toraks 2020 Jul;68(2):168-174

Department of Chest Diseases, Faculty of Medicine, Ankara University, Ankara, Turkey.

In recent years, high flow nasal cannula (HFNC) is a respiratory support system that has become prominent in the treatment of respiratory failure. HFNC provides higher concentration and flow of oxygen, resulting in decreasing anatomic dead space by preventing rebreathing and ensure positive end-expiratory. However, in COVID-19, the usage of HFNC is much controversial due to concerns about the benefits and risk of aerosol-dispersion. Read More

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http://dx.doi.org/10.5578/tt.69807DOI Listing

Prevalence and Management of Severe Hand, Foot, and Mouth Disease in Xiangyang, China, From 2008 to 2013.

Authors:
Jian Liu Jing Qi

Front Pediatr 2020 10;8:323. Epub 2020 Jul 10.

Department of Neurology, Affiliated Baoan Hospital of Shenzhen, Southern Medical University, Guangzhou, China.

Therapeutic strategies for severe hand, foot, and mouth disease (HFMD) are currently either inconsequent or deficient in evidence. We retrospectively surveyed HFMD outbreaks in Xiangyang from June 2008 to December 2013. HFMD is staged from I to V according to clinical severity. Read More

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http://dx.doi.org/10.3389/fped.2020.00323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366859PMC

Adverse Events in Coronavirus Disease Patients Management: A Pictorial Essay.

J Clin Imaging Sci 2020 21;10:42. Epub 2020 Jul 21.

Department of Radiology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Clinical manifestation of coronavirus disease (COVID-19) varies from asymptomatic to severe clinical forms that can result in acute respiratory distress syndrome or in multiple organ dysfunction syndromes. There are no guidelines, based on randomized controlled trials, for the treatment of COVID-19 patients. The treatment is based on antiviral drugs, invasive and non-invasive ventilation supports, and anticoagulant therapy. Read More

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http://dx.doi.org/10.25259/JCIS_72_2020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395525PMC

Leveraging IoTs and Machine Learning for Patient Diagnosis and Ventilation Management in the Intensive Care Unit.

IEEE Pervasive Comput 2020 Jul-Sep;19(3):68-78. Epub 2020 May 25.

University of California Davis.

Future healthcare systems will rely heavily on clinical decision support systems (CDSS) to improve the decision-making processes of clinicians. To explore the design of future CDSS, we developed a research-focused CDSS for the management of patients in the intensive care unit that leverages Internet of Things (IoT) devices capable of collecting streaming physiologic data from ventilators and other medical devices. We then created machine learning (ML) models that could analyze the collected physiologic data to determine if the ventilator was delivering potentially harmful therapy and if a deadly respiratory condition, acute respiratory distress syndrome (ARDS), was present. Read More

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http://dx.doi.org/10.1109/mprv.2020.2986767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402081PMC

Prognostic nomogram for elderly patients with acute respiratory failure receiving invasive mechanical ventilation: a nationwide population-based cohort study in Taiwan.

Sci Rep 2020 Aug 4;10(1):13161. Epub 2020 Aug 4.

Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.

Patients in critical care medicine are ageing. There is limited literature evaluating long-term outcomes and prognostic factors for the growing number of elderly patients with acute respiratory failure (ARF) receiving invasive mechanical ventilation (IMV). Data on elderly patients (≧ 65 years old) with ARF receiving intubation and IMV during 2003-2012 were retrospectively collected from the national health database in Taiwan. Read More

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http://dx.doi.org/10.1038/s41598-020-70130-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403322PMC

Effect of Coronavirus Disease 2019 in Pulmonary Circulation. The Particular Scenario of Precapillary Pulmonary Hypertension.

Diagnostics (Basel) 2020 Jul 31;10(8). Epub 2020 Jul 31.

Centro de Investigaciones Biomédicas En Red de enfermedades CardioVasculares (CIBERCV), 28029 Madrid, Spain.

The Coronavirus Disease of 2019 (COVID-19) has supposed a global health emergency affecting millions of people, with particular severity in the elderly and patients with previous comorbidities, especially those with cardiovascular disease. Patients with pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) could represent an especially vulnerable population because of the high mortality rates reported for respiratory infections. However, the number of COVID-19 cases reported among PAH and CTEPH patients is surprisingly low. Read More

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http://dx.doi.org/10.3390/diagnostics10080548DOI Listing

Time needed to intubate and suction a manikin prior to instituting positive pressure ventilation: a simulation trial.

Eur J Pediatr 2020 Aug 4. Epub 2020 Aug 4.

Department of Women and Children Health, University of Padova, Via Giustiniani, 3, 35128, Padova, Italy.

Tracheal suctioning in non-vigorous newborn delivered through meconium-stained amniotic fluid (MSAF) is supposed to delay initiation of positive pressure ventilation (PPV), but the magnitude of such delay is unknown. To compare the time of PPV initiation when performing immediate laryngoscopy with intubation and suctioning vs. performing immediate PPV without intubation in a manikin model. Read More

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http://dx.doi.org/10.1007/s00431-020-03759-5DOI Listing

Epidemiology, treatment and outcome of patients with lower respiratory tract infection presenting to emergency departments with dyspnoea (AANZDEM and EuroDEM studies).

Emerg Med Australas 2020 Aug 3. Epub 2020 Aug 3.

Joseph Epstein Centre for Emergency Medicine Research, Western Health, Melbourne, Victoria, Australia.

Objective: Lower respiratory tract infection (LRTI) is a frequent cause of dyspnoea in EDs, and is associated with considerable morbidity and mortality. We described and compared the management of this disease in Europe and Oceania/South-East Asia (SEA) cohorts.

Methods: We conducted a prospective cohort study with three time points in Europe and Oceania/SEA. Read More

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http://dx.doi.org/10.1111/1742-6723.13567DOI Listing

Setting and techniques for monitoring blood pressure during pregnancy.

Cochrane Database Syst Rev 2020 Jul 23;8:CD012739. Epub 2020 Jul 23.

Department of Women and Children's Health, King's College London, London, UK.

Background: Regular blood pressure (BP) measurement is crucial for the diagnosis and management of hypertensive disorders in pregnancy, such as pre-eclampsia. BP can be measured in various settings, such as conventional clinics or self-measurement at home, and with different techniques, such as using auscultatory or automated BP devices. It is important to understand the impact of different settings and techniques of BP measurement on important outcomes for pregnant women. Read More

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http://dx.doi.org/10.1002/14651858.CD012739.pub2DOI Listing

Accuracy of the clinical pulmonary infection score to differentiate ventilator-associated tracheobronchitis from ventilator-associated pneumonia.

Ann Intensive Care 2020 Aug 3;10(1):101. Epub 2020 Aug 3.

Department of Intensive Care Medicine, Critical Care Centre, CHU Lille, Lille, 59000, France.

Background: Differentiating Ventilator-Associated Tracheobronchitis (VAT) from Ventilator-Associated Pneumonia (VAP) may be challenging for clinicians, yet their management currently differs. In this study, we evaluated the accuracy of the Clinical Pulmonary Infection Score (CPIS) to differentiate VAT and VAP.

Methods: We performed a retrospective analysis based on the data from 2 independent prospective cohorts. Read More

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http://dx.doi.org/10.1186/s13613-020-00721-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396887PMC

Dead in the air? Case report highlighting need to adapt to CoVID adaptations.

Am J Emerg Med 2020 Jul 23. Epub 2020 Jul 23.

Department of Emergency Medicine, Internal Medicine, Anesthesia, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

During the recent CoVID-19 pandemic, airway management recommendations have been provided to decrease aerosolization and risk of viral spread to healthcare providers. High efficiency particulate air (HEPA) viral filters and adaptors are one way to decrease the risk of aerosolization during intubation. When placed proximal to the ventilator circuit, these viral filters and adaptors can create a significant amount of dead space, which in our smallest patients can significantly impact effective ventilation. Read More

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http://dx.doi.org/10.1016/j.ajem.2020.07.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377813PMC

Using airway resistance measurement to determine when to switch ventilator modes in congenital diaphragmatic hernia: a case report.

BMC Pediatr 2020 Aug 3;20(1):365. Epub 2020 Aug 3.

Department of Neonatology, Kanagawa Children's Medical Center, 4-138-2 Mutsukawa Minamiku Yokohama, Yokohama, Kanagawa, 232-2351, Japan.

Background: Congenital diaphragmatic hernia is a deficiency of the fetal diaphragm resulting in herniation of the abdominal viscera into the thoracic cavity. The best method of respiratory management of congenital diaphragmatic hernia is unclear, but high frequency oscillatory ventilation is often used as the initial ventilator mode for severe congenital diaphragmatic hernia. When it becomes impossible to maintain the pre-ductal saturations, the timing of successful switching of the ventilation mode from high frequency oscillatory ventilation to conventional mechanical ventilation remains unclear. Read More

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http://dx.doi.org/10.1186/s12887-020-02258-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396326PMC

Deresuscitation in Patients with Abdominal Sepsis Carries a Lower Mortality Rate and Less Organ Dysfunction than Conservative Fluid Management.

Surg Infect (Larchmt) 2020 Aug 3. Epub 2020 Aug 3.

Department of Intensive Care Unit, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, People's Republic of China.

The relation between deresuscitative fluid management after the resuscitation phase and clinical outcome in patients with abdominal sepsis is not completely clear. The aim of this study was to assess the contribution of deresuscitative management to death and organ dysfunction in abdominal sepsis. Consecutive patients with abdominal sepsis requiring fluid resuscitation were included in this study. Read More

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http://dx.doi.org/10.1089/sur.2019.370DOI Listing

Invasive Mechanical Ventilation in Chronic Obstructive Pulmonary Disease Exacerbations.

Semin Respir Crit Care Med 2020 Aug 3. Epub 2020 Aug 3.

Intensive Care Unit, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.

Chronic obstructive pulmonary disease (COPD) continues to be an important cause of morbidity, mortality, and health care costs worldwide. Although there exist some heterogeneity between patients, the course of COPD is characterized by recurrent acute exacerbations, which are among the most common causes of medical admission to hospital. Patients with frequent exacerbations have accelerated lung function decline, worse quality of life, and greater mortality. Read More

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http://dx.doi.org/10.1055/s-0040-1714396DOI Listing

Prevention and Management of Delirium in the Intensive Care Unit.

Semin Respir Crit Care Med 2020 Aug 3. Epub 2020 Aug 3.

Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.

Delirium is a debilitating form of brain dysfunction frequently encountered in the intensive care unit (ICU). It is associated with increased morbidity and mortality, longer lengths of stay, higher hospital costs, and cognitive impairment that persists long after hospital discharge. Predisposing factors include smoking, hypertension, cardiac disease, sepsis, and premorbid dementia. Read More

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http://dx.doi.org/10.1055/s-0040-1710572DOI Listing

Use of the IL-6R Antagonist Tocilizumab in Hospitalized COVID-19 Patients.

J Intern Med 2020 Aug 3. Epub 2020 Aug 3.

Center for Blood Disorders and Stem Cell Transplantation, Swedish Cancer Institute, Swedish Medical Center, Seattle, WA, USA.

Severely ill COVID-19 patients have a high risk of admission to the intensive-care unit (ICU) and requirement for mechanical ventilation (MV), with in-hospital mortality reported as 18-79% globally. . Among ICU patients in the United States (US), centers have reported 50% mortality. Read More

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http://dx.doi.org/10.1111/joim.13163DOI Listing

Extracorporeal membrane oxygenation use in Trauma Quality Improvement Program centers: Temporal trends and future directions.

J Trauma Acute Care Surg 2020 Aug;89(2):351-357

From the Institute of Health Policy, Management, and Evaluation (M.P.G., B.W.T., A.B.N., B.H.), Department of Surgery (M.P.G., D.P., A.B.N., B.H.), Interdepartmental Division of Critical Care Medicine, Department of Medicine (B.W.T., B.H.), University of Toronto, Toronto, Ontario; Royal Canadian Medical Service (D.P.), Ottawa, Ontario, Canada; Sunnybrook Health Sciences Centre (M.P.G., B.W.T., D.P., M.V., A.B.N., B.H.); and Sunnybrook Research Institute (A.B.N., B.H.), Toronto, Ontario, Canada.

Background: Increased clinical experience and the decreased need for systemic anticoagulation have renewed interest in the use of extracorporeal membrane oxygenation (ECMO) for posttraumatic respiratory and cardiopulmonary failure. The objectives of this study were to describe the incidence and temporal trends of ECMO use at trauma centers, the outcomes of trauma patients undergoing ECMO, and the characteristics of trauma centers providing ECMO.

Methods: Data were derived from the American College of Surgeons Trauma Quality Improvement Program data set. Read More

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http://dx.doi.org/10.1097/TA.0000000000002756DOI Listing

Clinical Course and Outcomes of 3,060 Patients with Coronavirus Disease 2019 in Korea, January-May 2020.

J Korean Med Sci 2020 Aug 3;35(30):e280. Epub 2020 Aug 3.

Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.

Background: The fatality rate of patients with coronavirus disease 2019 (COVID-19) varies among countries owing to demographics, patient comorbidities, surge capacity of healthcare systems, and the quality of medical care. We assessed the clinical outcomes of patients with COVID-19 during the first wave of the epidemic in Korea.

Methods: Using a modified World Health Organization clinical record form, we obtained clinical data for 3,060 patients with COVID-19 treated at 55 hospitals in Korea. Read More

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http://dx.doi.org/10.3346/jkms.2020.35.e280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402927PMC