26,206 results match your criteria Ventilation Management

Rewarming from unwitnessed hypothermic cardiac arrest with good neurological recovery using extracorporeal membrane oxygenation.

Perfusion 2022 Aug 18:2676591221122274. Epub 2022 Aug 18.

Department of Cardiothoracic Anaesthesia and Intensive Care, 105565Newcastle upon Tyne Hospitals NHS Foundation Trust, UK.

A 26-year-old man, who was training in bad weather for a mountain ultramarathon, became hypothermic after running for 4 h. He deteriorated and was unable to continue. His running partner went for help. Read More

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Emergency Management of Ventilation Failure Through Blocked Tracheostomy Tube in a Paediatric Patient.

Cureus 2022 Jul 14;14(7):e26873. Epub 2022 Jul 14.

Anesthesia and Critical Care, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, PAK.

The most common complication of tracheostomy tubes in children is blockage of the tube. We report a case where ventilation after induction of anaesthesia was not possible even though there were no signs of impending obstruction. An eight-year-old child, recently diagnosed with left tonsillar embryonal rhabdomyosarcoma, presented for an MRI face and bone marrow biopsy before starting treatment. Read More

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Management and outcomes of pregnant women admitted to intensive care unit for severe pneumonia related to SARS-CoV-2 infection: the multicenter and international COVIDPREG study.

Intensive Care Med 2022 Aug 17. Epub 2022 Aug 17.

Service de Médecine Intensive Réanimation, Centre Hospitalier Universitaire de Nice, Hôpital l'Archet 1, 151 rue saint Antoine de Ginestière, 06200, Nice, France.

Purpose: Management and outcomes of pregnant women with coronavirus disease 2019 (COVID-19) admitted to intensive care unit (ICU) remain to be investigated.

Methods: A retrospective multicenter study conducted in 32 ICUs in France, Belgium and Switzerland. Maternal management as well as maternal and neonatal outcomes were reported. Read More

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The use of ICU resources in CAR-T cell recipients: a hospital-wide study.

Ann Intensive Care 2022 Aug 17;12(1):75. Epub 2022 Aug 17.

AP-HP, Hôpital Saint-Louis, Medical ICU, 1 avenue Claude Vellefaux, 75010, Paris, France.

Background: CAR-T cell (chimeric antigen receptor T) therapy has emerged as an effective treatment of refractory hematological malignancies. Intensive care management is intrinsic to CAR-T cell therapy. We aim to describe and to assess outcomes in critically ill CAR-T cell recipients. Read More

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Vertebral artery dissecting aneurysm rupture under severe COVID-19.

Brain Hemorrhages 2022 Aug 12. Epub 2022 Aug 12.

Department of Neurosurgery, Mie University Graduate School of Medicine, Tsu, Japan.

Objective: We report a rare case of subarachnoid hemorrhage (SAH) caused by a ruptured vertebral artery (VA) dissecting aneurysm (DA) under severe COVID-19 treatment, and discuss the potential relationships.Case presentationA 58-year-old woman with COVID-19 fell into severe pneumonia needing mechanical ventilation at 10 days post-onset (day 10). The patient had no risk factors for DA or stroke other than COVID-19 infection. Read More

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Comparison of Conventional Oxygen Therapy With High-Flow Nasal Oxygenation in the Management of Hypercapnic Respiratory Failure.

Cureus 2022 Jul 13;14(7):e26815. Epub 2022 Jul 13.

Anaesthesiology and Critical Care, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, IND.

Introduction: The effectiveness of high-flow nasal oxygenation (HFNO) in patients with hypercapnic respiratory failure (RF) remains controversial. The current study compared the effectiveness of HFNO in patients with hypercapnic RF with conventional oxygen therapy (COT).

Objectives: The primary objective was to compare changes in the partial pressure of carbon dioxide (PaCO2) between those receiving COT and HFNO. Read More

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Clinical Characteristics and Outcomes of COVID-19 Acute Respiratory Distress Syndrome (ARDS) Survivors in Early Pandemic: A Single Healthcare System Retrospective Study.

Cureus 2022 Jul 13;14(7):e26801. Epub 2022 Jul 13.

Pulmonary and Critical Care Medicine, University of Florida, Gainesville, USA.

Introduction:  Acute respiratory distress syndrome (ARDS) management in the intensive care unit (ICU) has attracted strong interest since the start of the COVID-19 pandemic. Our retrospective study aims to describe the outcomes and predictors of mortality of ARDS associated with COVID-19 within one university-based healthcare system.

Methods:  We identified 165 patients within our healthcare system during the months of April 2020 through July 2020, who were admitted to our medical ICUs and eligible for our study. Read More

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A Comparative Study of Bilateral Erector Spinae Block Versus Intravenous Dexmedetomidine for Perioperative Pain Management in Patients Undergoing Off-Pump Coronary Artery Bypass Grafting - A Single-Blind Randomized Controlled Trial.

J Cardiothorac Vasc Anesth 2022 Jul 16. Epub 2022 Jul 16.

Department of Anaesthesiology, Sri Ramachandra Institute of Higher Education and Research (SRIHER), Chennai, India.

Objective: Regional analgesia, along with general anesthesia, reduce postoperative pain. In this study, the authors compared the erector spinae plane (ESP) block having dexmedetomidine as an adjuvant with conventional pain management along with intravenous dexmedetomidine.

Design: Prospective randomized single-blinded trial. Read More

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Integration of machine learning with complex industrial mining systems for reduced energy consumption.

Front Artif Intell 2022 27;5:938641. Epub 2022 Jul 27.

Department of Industrial Engineering, Stellenbosch University, Stellenbosch, South Africa.

The deep-level mining industry is experiencing narrowing profit margins due to increasing operating costs and decreasing production. The industry is known for its lack of dynamic control across complex integrated systems running deep underground, making IoT technologies difficult to implement. An important integrated system in a typical underground mine is the refrigeration-ventilation system. Read More

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Clinical characteristics and risk factors associated with ICU-acquired infections in sepsis: A retrospective cohort study.

Front Cell Infect Microbiol 2022 28;12:962470. Epub 2022 Jul 28.

Department of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Intensive care unit (ICU)-acquired infection is a common cause of poor prognosis of sepsis in the ICU. However, sepsis-associated ICU-acquired infections have not been fully characterized. The study aims to assess the risk factors and develop a model that predicts the risk of ICU-acquired infections in patients with sepsis. Read More

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Cardiovascular Complications of Pregnancy-Associated COVID-19 Infections.

JACC Adv 2022 Aug 10:100057. Epub 2022 Aug 10.

Division of Cardiology, Piedmont Heart Institute, Atlanta, Georgia, USA.

Cardiovascular complications are frequently present in coronavirus 2019 (COVID-19) infection. These include microvascular and macrovascular thrombotic complications such as arterial and venous thromboembolism, myocardial injury or inflammation resulting in infarction, heart failure, and arrhythmias. Data suggest increased risk of adverse outcomes in pregnant compared with nonpregnant women of reproductive age with COVID-19 infection, including need for intensive care unit admission, mechanical ventilation, and extracorporeal membrane oxygenation utilization. Read More

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Study of the Diffusion Law of Harmful Gases in Tunnel Construction on Plateaus and Optimization of Ventilation Parameters.

ACS Omega 2022 Aug 25;7(31):27135-27148. Epub 2022 Jul 25.

Faculty of Public Security and Emergency Management, Kunming University of Science and Technology, Kunming 650093, China.

To explore the diffusion law of harmful gases near the excavation face in tunnel construction on plateaus, select the optimal ventilation parameters, and improve the ventilation efficiency, Ansys Fluent was used to set the environmental parameters according to the highland, where the tunnel is located, and simulate and curve fit the diffusion phenomenon of CO and NO based on the fluid control equations and species transport model. The effects of air velocity, ventilation time, and duct position on the diffusion law of harmful gases were analyzed, from which the optimal ventilation conditions were selected, and the ventilation effects under the optimal conditions were compared with those under the original conditions. The study shows that after the fresh airflow passes through the outlet, part of it flows out along the tunnel wall toward the cave entrance, and the other part interacts with the return air to form a vortex; when the air supply speed is 10 m/s and the distance from the duct outlet to the excavation face is 25 m, the maximum concentration of harmful gases decreases by 92-99% after 20 min of ventilation compared with that before optimization and the smoke exhaust efficiency increases by 2. Read More

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IPF Respiratory Symptoms Management - Current Evidence.

Front Med (Lausanne) 2022 28;9:917973. Epub 2022 Jul 28.

Department of Pulmonology, Medical University of Gdańsk, Gdańsk, Poland.

Idiopathic pulmonary fibrosis (IPF) is a progressive, chronic disease of the lungs which is characterized by heavy symptom burden, especially in the last year of life. Despite recently established anti-fibrotic treatment IPF prognosis is one of the worst among interstitial lung diseases. In this review available evidence regarding pharmacological and non-pharmacological management of the main IPF symptoms, dyspnea and cough, is presented. Read More

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Colorectal Surgery in Critically Unwell Patients: A Multidisciplinary Approach.

Clin Colon Rectal Surg 2022 May 9;35(3):244-260. Epub 2022 Feb 9.

Adult Intensive Care Services, the Prince Charles Hospital, Brisbane, Queensland, Australia.

A proportion of patients require critical care support following elective or urgent colorectal procedures. Similarly, critically ill patients in intensive care units may also need colorectal surgery on occasions. This patient population is increasing in some jurisdictions given an aging population and increasing societal expectations. Read More

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Brain-Lung Crosstalk: Management of Concomitant Severe Acute Brain Injury and Acute Respiratory Distress Syndrome.

Curr Treat Options Neurol 2022 Aug 10:1-26. Epub 2022 Aug 10.

Department of Neurology, University of Washington, Seattle, WA USA.

Purpose Of Review: To summarize pathophysiology, key conflicts, and therapeutic approaches in managing concomitant severe acute brain injury (SABI) and acute respiratory distress syndrome (ARDS).

Recent Findings: ARDS is common in SABI and independently associated with worse outcomes in all SABI subtypes. Most landmark ARDS trials excluded patients with SABI, and evidence to guide decisions is limited in this population. Read More

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Successful Treatment of a Patient with COVID-19-Induced Severe ARDS, Pneumothorax, and Pneumomediastinum with Awake vv-ECMO Implantation.

Case Rep Crit Care 2022 10;2022:6559385. Epub 2022 Aug 10.

Department of Anaesthesia and Surgical Intensive Care Medicine, University Hospital Augsburg, Stenglinstr. 2, 86156 Augsburg, Germany.

Management of acute respiratory distress syndrome (ARDS) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still a challenge for the staff on intensive-care units (ICU's) around the world. Many of these patients are treated with invasive ventilation. Sometimes, the occurrence of pneumothorax and/or pneumomediastinum can complicate the course of the disease because initiation of invasive ventilation might be fatal in those patients. Read More

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Management of life-threatening malignant central airway obstruction: A novel approach of using extracorporeal membrane oxygenation with tumor debulking and stenting.

Respir Med Case Rep 2022 31;39:101718. Epub 2022 Jul 31.

Pulmonary, Critical Care & Sleep Medicine Section, College of Medicine, University of Oklahoma Health Sciences Center, 73104, USA.

Extracorporeal membrane oxygenation (ECMO) is an artificial lung or heart used to oxygenate and circulate blood. Veno-venous ECMO is most commonly used as an emergency therapy in patients with acute respiratory distress syndrome (ARDS), but it has the potential to be useful in other respiratory-related diseases. We report a case where ECMO successfully allowed for interventional pulmonary procedures in a patient with life-threatening tracheal obstruction secondary to lung cancer, requiring tumor debulking and silicone Y stent placement. Read More

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Severe COVID-19 disease in a 2nd trimester pregnancy: Successful ECMO and mechanical ventilation management.

Respir Med Case Rep 2022 10;39:101721. Epub 2022 Aug 10.

Division of Pulmonary, Allergy, and Critical Care Medicine, Stanford University Medical Center, Stanford, CA, 94305, USA.

Extracorporeal membrane oxygenation (ECMO) is an invasive support strategy for cardiac, respiratory, or combined cardiorespiratory failure. ECMO has become increasing utilized in patients with severe respiratory failure due to COVID-19 infection. To our knowledge there is no report of successful ECMO utilization in second trimester of pregnancy leading to a successful outcome. Read More

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Comparison of Stroke Volume Variation-based goal-directed Therapy Versus Standard Fluid Therapy in Patients Undergoing Head and Neck Surgery: A Randomized Controlled Study.

Balkan Med J 2022 Aug 15. Epub 2022 Aug 15.

Department of Anesthesiology, İstanbul Faculty of Medicine, İstanbul University, İstanbul, Turkey.

Background: Perioperative fluid therapy is used to avoid dehydration and hypovolemia. Optimum perioperative fluid administration may improve postoperative outcomes after major surgery, and the optimal strategy remains controversial and uncertain.

Aims: The primary outcome was the total amount of intraoperative fluids given between perioperative goal-directed fluid therapy (GDFT) guided by a hemodynamic monitoring system and standard fluid therapy based on "mean arterial pressure-diuresis" data in patients undergoing head and neck surgery. Read More

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Andrew P Binks

Handb Clin Neurol 2022 ;188:309-338

Department of Basic Science Education, Virginia Tech Carilion School of Medicine, Roanoke, VA, United States; Faculty of Health Sciences, Virginia Tech, Blacksburg, VA, United States. Electronic address:

The clinical term dyspnea (a.k.a. Read More

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Laryngotracheal separation through the cricoid ring for management of tracheobronchomegaly.

Int J Pediatr Otorhinolaryngol 2022 Aug 4;161:111266. Epub 2022 Aug 4.

Division of Pediatric Otolaryngology-Head and Neck Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA; Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, OH, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA; Aerodigestive Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. Electronic address:

Tracheobronchomegaly is a rare condition characterized by diffuse dilation of the trachea and main bronchi. In ventilator-dependent neonates with tracheobronchomegaly, a tracheostomy may be hazardous due to the lack of an appropriate tracheostomy tube size that can fit the enlarged trachea. Here, we describe a modification of the laryngotracheal separation procedure to permit ventilation in a child with tracheobronchomegaly and severe bronchopulmonary dysplasia. Read More

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Comparison of apnoeic oxygen techniques in term pregnant subjects: a computational modelling study.

Br J Anaesth 2022 Aug 10. Epub 2022 Aug 10.

Nottingham University Hospitals NHS Trust, Nottingham, UK; Anaesthesia and Critical Care, Academic Unit of Injury, Recovery and Inflammation Sciences, School of Medicine, University of Nottingham, Nottingham, UK.

Background: Hypoxaemia during general anaesthesia can cause harm. Apnoeic oxygenation extends safe apnoea time, reducing risk during airway management. We hypothesised that low-flow nasal oxygenation (LFNO) would extend safe apnoea time similarly to high-flow nasal oxygenation (HFNO), whilst allowing face-mask preoxygenation and rescue. Read More

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Effect of procedural volume on the outcomes of congenital heart surgery in Japan.

J Thorac Cardiovasc Surg 2022 Jun 18. Epub 2022 Jun 18.

Japanese Society of Pediatric Cardiology and Cardiac Surgery, Tokyo, Japan.

Objectives: The present study developed a new risk model for congenital heart surgery in Japan and determined the relationship between hospital procedural volume and mortality using the developed model.

Methods: We analyzed 47,164 operations performed between 2013 and 2018 registered in the Japan Cardiovascular Surgery Database-Congenital and created a new risk model to predict the 90-day/in-hospital mortality using the Japanese congenital heart surgery mortality categories and patient characteristics. The observed/expected ratios of mortality were compared among 4 groups based on annual hospital procedural volume (group A [5539 procedures performed in 90 hospitals]: ≤50, group B [9322 procedures in 24 hospitals]: 51-100, group C [13,331 procedures in 21 hospitals]: 101-150, group D [18,972 procedures in 15 hospitals]: ≥151). Read More

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E-cigarette or vaping product use-associated lung injury: A review of clinico-radio-pathological characteristics.

Respir Investig 2022 Aug 10. Epub 2022 Aug 10.

Department of Radiology, University of Iowa Hospitals and Clinics, 200 Hawkins Dr, Iowa City, IA 52242, USA; Department of Radiology, University of Wisconsin-Madison, Madison, WI 53706, USA. Electronic address:

Aggressive, albeit false marketing of electronic nicotine delivery systems (ENDS) or vaping devices as safer alternatives to cigarette smoking, combined with lack of regulations, has led to its mass adoption, especially among youth. A sudden increase in acute lung injuries was noted in 2019 which was linked to ENDS. It was termed by the Centers for Disease Control and Prevention (CDC) as electronic cigarette or vaping product use-associated lung injury (EVALI). Read More

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Pulmonary hypertension in the newborn- etiology and pathogenesis.

Semin Fetal Neonatal Med 2022 Aug 7:101381. Epub 2022 Aug 7.

Division of Neonatology, Department of Pediatrics, University of California, Davis, California, USA. Electronic address:

A disruption in the well-orchestrated fetal-to-neonatal cardiopulmonary transition at birth results in the clinical conundrum of severe hypoxemic respiratory failure associated with elevated pulmonary vascular resistance (PVR), referred to as persistent pulmonary hypertension of the newborn (PPHN). In the past three decades, the advent of surfactant, newer modalities of ventilation, inhaled nitric oxide, other pulmonary vasodilators, and finally extracorporeal membrane oxygenation (ECMO) have made giant strides in improving the outcomes of infants with PPHN. However, death or the need for ECMO occurs in 10-20% of term infants with PPHN. Read More

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Impact of sleep-disordered breathing on the management of children with Chiari malformation type I.

Pediatr Pulmonol 2022 Aug 13. Epub 2022 Aug 13.

Pediatric noninvasive ventilation and sleep unit, AP-HP, Hôpital Necker-Enfants malades, F-75015, Paris, France.

Objectives: Children with Chiari Malformation type I (CM-I) have an increased risk of sleep apnea. The aim of the study was to describe the management of CM-I patients in relation to symptoms, magnetic resonance imaging (MRI) findings and sleep apnea syndrome (SAS).

Methods: We performed a retrospective analysis of clinical charts of all 57 CM-I patients seen between September 2013 and April 2017. Read More

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Long-Term Clinical Trajectory of Patients with Subarachnoid Hemorrhage: Linking Acute Care and Neurorehabilitation.

Neurocrit Care 2022 Aug 12. Epub 2022 Aug 12.

Neurological Intensive Care Unit, Department of Neurology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.

Background: Despite improvements in the critical care management of subarachnoid hemorrhage (SAH), a substantial number of patients still suffer from disabilities. In most areas of the world, longitudinal follow-up is not routinely performed, and the patient's trajectory remains unknown.

Methods: We prospectively collected data of 298 consecutive patients with spontaneous SAH and evaluated clinical trajectories at discharge, 3 months, and 1 year after SAH. Read More

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Anesthesia for Global General Thoracic Surgery.

Thorac Surg Clin 2022 Aug;32(3):307-315

Department of Anesthesiology, University of North Carolina School of Medicine, N2198 UNC Hospitals, CB#7010 Chapel Hill, NC 27599-7010 USA. Electronic address:

Anesthesia in low-to-middle income countries (LMICs) is often provided by nonphysician anesthetists. The training and resources for anesthesia in LMICs are limited, and this must be evaluated when starting or expanding a thoracic surgery program in LMICs. The ability to access a patient's baseline pulmonary and cardiovascular status is often based on rudimentary studies and a thorough history and physical. Read More

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At-Home End-Tidal Carbon Dioxide Measurement in Children with Invasive Home Mechanical Ventilation.

Pediatr Pulmonol 2022 Aug 12. Epub 2022 Aug 12.

Division of Pulmonary and Sleep Medicine, Department of Pediatrics, Northwestern University Feinberg School of Medicine.

Background: Carbon dioxide concentration trending is used in chronic management of children with invasive home mechanical ventilation (HMV) in clinical settings, but options for end-tidal carbon dioxide (EtCO ) monitoring at home are limited. We hypothesized that a palm-sized, portable endotracheal capnograph (PEC) that measures EtCO could be adapted for in-home use in children with HMV.

Methods: We evaluated the internal consistency of the PEC by calculating an intra-class correlation coefficient of 3 back-to-back breaths by children (0-17 years) at baseline health in clinic. Read More

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Vitamin D Levels and Length of Hospitalization in Indian Patients With COVID-19: A Single-Center Prospective Study.

Cureus 2022 Jul 9;14(7):e26704. Epub 2022 Jul 9.

Department of Internal and Pulmonary Medicine, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, IND.

Introduction The role of vitamin D deficiency in increasing susceptibility or modifying outcomes in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) illness is unclear, and data about the association is scant in low- and middle-income countries. We set out to investigate any correlation between baseline vitamin D status and the length of hospital stay in laboratory-confirmed SARS-CoV-2 patients in India. Methods Two hundred patients with SARS-CoV-2 infection requiring admission in a North Indian 1200-bedded tertiary care hospital were recruited prospectively from November 2020 to March 2021. Read More

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