29,167 results match your criteria Ventilation Management


Case report of successful management of intraoperative tracheal rupture during thoracoscopic esophageal resection in patient with esophageal cancer.

Int J Surg Case Rep 2019 Mar 9;57:42-46. Epub 2019 Mar 9.

NGHCI Railway Clinical Hospital at the "Rostov-Glavnyy" Station, OAO Russian Railways, Varfolomeeva Street 92, Rostov-on-Don, Russian Federation; FSBEI HE Rostov State Medical University of the Ministry of Health of the Russian Federation, Nakhichevansky Lane 19, Rostov-on-Don, Russian Federation.

Introduction: A rupture of the membranous part of trachea during thoracoscopic and transhiatal resection of esophagus is a rare complication that occurs in 0.4% of cases. This complication often requires thoracotomy and is associated with prolonged pulmonary ventilation, long-term pleural draining due to persistent air leakage and development of a tracheopleural fistula, prolonged hospitalization, and high risk of septic and secondary cardiorespiratory complications. Read More

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http://dx.doi.org/10.1016/j.ijscr.2019.02.045DOI Listing

Noninvasive ventilation in critically ill patients with the Middle East respiratory syndrome.

Influenza Other Respir Viruses 2019 Mar 18. Epub 2019 Mar 18.

Intensive Care Department, King Abdullah International Medical Research Center, College of Medicine, King Abdulaziz Medical City, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

Background: Noninvasive ventilation (NIV) has been used in patients with the Middle East respiratory syndrome (MERS) with acute hypoxemic respiratory failure, but the effectiveness of this approach has not been studied.

Methods: Patients with MERS from 14 Saudi Arabian centers were included in this analysis. Patients who were initially managed with NIV were compared to patients who were managed only with invasive mechanical ventilation (invasive MV). Read More

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http://dx.doi.org/10.1111/irv.12635DOI Listing

Long-term Cognitive and Functional Impairments After Critical Illness.

Anesth Analg 2019 Apr;128(4):772-780

From the Department of Anesthesiology, Division of Anesthesiology Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee.

As critical illness survivorship increases, patients and health care providers are faced with management of long-term sequelae including cognitive and functional impairment. Longitudinal studies have demonstrated impairments persisting at least 1-5 years after hospitalization for critical illness. Cognitive domains impacted include memory, attention, and processing speed. Read More

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http://dx.doi.org/10.1213/ANE.0000000000004066DOI Listing

Intravenous Sedation in Arnold-Chiari Malformation With Respiratory Failure.

Anesth Prog 2019 ;66(1):37-41

Department of Dental Anesthesiology, Nippon Dental University School of Life Dentistry, Tokyo, Japan.

Type II Arnold-Chiari malformation (ACM) is an abnormality in which the cerebellum, pons, and medulla oblongata are displaced downward into the spinal cord. Type II ACM is often complicated by respiratory depression, sleep-disordered breathing, and deglutition disorder as a result of medullary dysfunction and impairment of the lower cranial nerves. Bending and stretching of the neck is restricted, and anesthetic management is problematic in patients with the disorder. Read More

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http://dx.doi.org/10.2344/anpr-66-01-06DOI Listing
January 2019

ABCDE and ABCDEF care bundles: A systematic review protocol of the implementation process in intensive care units.

Medicine (Baltimore) 2019 Mar;98(11):e14792

Graduate Program in Pharmaceutical Sciences, University of Sorocaba, Sorocaba, São Paulo.

Background: The awakening and breathing coordination of daily sedation and ventilator removal trials, delirium monitoring and management, and early mobility and exercise (ABCDE) and assessment, prevent and manage pain, both spontaneous awakening and spontaneous breathing trials, choice of analgesia and sedation, assess, prevent and manage delirium, early mobility and exercise, family engagement (ABCDEF) bundles are part of the science of the liberation of the intensive care unit (ICU). There are not enough studies that have evaluated the effectiveness and safety of the implementation of these bundles. This study will analyze the implementation process, estimate their effectiveness and safety, and identify barriers, facilitators and attitudes that have influenced the implementation process. Read More

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http://dx.doi.org/10.1097/MD.0000000000014792DOI Listing

Effect of Neurally Adjusted Ventilatory Assist on Patient-Ventilator Interaction in Mechanically Ventilated Adults: A Systematic Review and Meta-Analysis.

Crit Care Med 2019 Mar 15. Epub 2019 Mar 15.

Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada.

Objectives: Patient-ventilator asynchrony is common among critically ill patients undergoing mechanical ventilation and has been associated with adverse outcomes. Neurally adjusted ventilatory assist is a ventilatory mode that may lead to improved patient-ventilator synchrony. We conducted a systematic review to determine the impact of neurally adjusted ventilatory assist on patient-ventilator asynchrony, other physiologic variables, and clinical outcomes in adult patients undergoing invasive mechanical ventilation in comparison with conventional pneumatically triggered ventilatory modes. Read More

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http://dx.doi.org/10.1097/CCM.0000000000003719DOI Listing

The Crashing Obese Patient.

West J Emerg Med 2019 Mar 6;20(2):323-330. Epub 2019 Feb 6.

University of Maryland School of Medicine, Department of Emergency Medicine, Baltimore, Maryland.

Emergency physicians (EP) frequently resuscitate and manage critically ill patients. Resuscitation of the crashing obese patient presents a unique challenge for even the most skilled physician. Changes in anatomy, metabolic demand, cardiopulmonary reserve, ventilation, circulation, and pharmacokinetics require special consideration. Read More

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http://dx.doi.org/10.5811/westjem.2018.12.41085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404698PMC

Comprehensive evaluation of manikin-based airway training with second generation supraglottic airway devices.

Ther Clin Risk Manag 2019 1;15:367-376. Epub 2019 Mar 1.

Department of Anesthesiology and Critical Care, Medical Center, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany,

Background: Supraglottic airway devices (SADs) are an essential second line tool during difficult airway management after failed tracheal intubation. Particularly for such challenging situations the handling of an SAD requires sufficient training. We hypothesized that the feasibility of manikin-based airway management with second generation SADs depends on the type of manikin. Read More

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http://dx.doi.org/10.2147/TCRM.S194728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400128PMC

Use of End Tidal Oxygen Monitoring to Assess Preoxygenation During Rapid Sequence Intubation in the Emergency Department.

Ann Emerg Med 2019 Mar 14. Epub 2019 Mar 14.

Department of Emergency Medicine, University of Arizona College of Medicine, Tucson, AZ.

Study Objective: Preoxygenation is important to prevent oxygen desaturation during emergency airway management. The purpose of this study is to describe the use of end tidal oxygen (eto) during rapid sequence intubation in the emergency department.

Methods: This study was carried out in 2 academic centers in Sydney, Australia, and New York City. Read More

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http://dx.doi.org/10.1016/j.annemergmed.2019.01.038DOI Listing

COPD: Rethinking Patient Management - How to Approach a Challenging Patient Group Successfully.

Respiration 2019 Mar 15:1-6. Epub 2019 Mar 15.

Clinic for Pneumology and Allergology, Centre of Sleep Medicine and Respiratory Care, Bethanien Hospital, Institute of Pneumology, University of Cologne, Solingen, Germany.

In comparison to other chronically ill people, patients suffering from chronic obstructive pulmonary disease (COPD) have many additional difficulties to face and conquer. Due to the contribution of avoidable causes of their illness ("smokers' lung"), society holds people with COPD responsible for their disease, which in return often leads to stigmatization and social isolation. In addition, COPD patients commonly belong to a less privileged social class, own a low socioeconomic status, and lower education. Read More

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http://dx.doi.org/10.1159/000493759DOI Listing

Differences in neurosurgical treatment of intracerebral haemorrhage: a nation-wide observational study of 578 consecutive patients.

Acta Neurochir (Wien) 2019 Mar 15. Epub 2019 Mar 15.

Department of Neuroscience, Neurosurgery, Uppsala University, Uppsala University Hospital, SE-751 85, Uppsala, Sweden.

Background: Supratentorial intracerebral haemorrhage (ICH) carries an excessive mortality and morbidity. Although surgical ICH treatment can be life-saving, the indications for surgery in larger cohorts of ICH patients are controversial and not well defined. We hypothesised that surgical indications vary substantially among neurosurgical centres in Sweden. Read More

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http://dx.doi.org/10.1007/s00701-019-03853-0DOI Listing

Subglottic stenosis in children: Our experience at a pediatric tertiary center for 8 years in South Korea.

Int J Pediatr Otorhinolaryngol 2019 Feb 27;121:64-67. Epub 2019 Feb 27.

Department of Otolaryngology - Head and Neck Surgery, College of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, South Korea. Electronic address:

Objective: The incidence of SGS has been reported to be less than 8% after endotracheal intubation. Therefore there is an increasing trend in the number of patients with acute acquired SGS due to mechanical ventilation in the intensive care unit. However, there have been no reports describing the treatment of SGS in children in South Korea. Read More

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http://dx.doi.org/10.1016/j.ijporl.2019.02.044DOI Listing
February 2019

Obesity hypoventilation syndrome.

Eur Respir Rev 2019 Mar 14;28(151). Epub 2019 Mar 14.

CIBER de enfermedades respiratorias (CIBERES), Madrid, Spain.

Obesity hypoventilation syndrome (OHS) is defined as a combination of obesity (body mass index ≥30 kg·m), daytime hypercapnia (arterial carbon dioxide tension ≥45 mmHg) and sleep disordered breathing, after ruling out other disorders that may cause alveolar hypoventilation. OHS prevalence has been estimated to be ∼0.4% of the adult population. Read More

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http://err.ersjournals.com/lookup/doi/10.1183/16000617.0097-
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http://dx.doi.org/10.1183/16000617.0097-2018DOI Listing
March 2019
1 Read

Systematic Review of Capnography with Mask Ventilation during Cardiopulmonary Resuscitation Maneuvers.

J Clin Med 2019 Mar 13;8(3). Epub 2019 Mar 13.

Physiotherapy Department at the University of Balearic Islands, Ctra. de Valldemossa, km 7.5, 07122 Palma de Mallorca, Balearic Islands, Spain.

The latest guidelines identify capnography as an instrument used to assess bag-valve-mask ventilation during cardiopulmonary resuscitation (CPR). In this review, we analyzed the feasibility and reliability of capnography use with face mask ventilation during CPR maneuvers in adults and children. This systematic review was completed in December 2018; data for the study were obtained from the following databases: EBSCOhost, SCOPUS, PubMed, Índice Bibliográfico Español en Ciencias de la Salud (IBECS), TESEO, and Cochrane Library Plus. Read More

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http://dx.doi.org/10.3390/jcm8030358DOI Listing

[Acute inpatient treatment of severe burns].

Rev Prat 2018 Dec;68(10):1087-1091

Centre de traitement des brûlés, hôpital d'instruction des armées Percy, Clamart, France.

Acute inpatient treatment of severe burns. Acute in-hospital care of severely burned patients intricately combines surgery and intensive care. Systemic and supportive care is centered on hemodynamic management of the initial plasmorrhagic shock, airway control, enteral nutrition in order to compensate for hypercatabolism, analgesia and adjuncts. Read More

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December 2018
1 Read

Thoracoscopy in prone position with two-lung ventilation compared to conventional thoracotomy during Ivor Lewis procedure: a multicenter case-control study.

Surg Endosc 2019 Mar 13. Epub 2019 Mar 13.

Digestive and Minimally Invasive Surgery Unit, Department of Digestive Surgery and Transplantation, Saint Eloi Hospital, University of Montpellier - Nîmes, 80 Avenue Augustin Fliche, 34295, Montpellier, France.

Background: Intraoperative management based on thoracoscopy, prone position and two-lung ventilation could decrease the rate of postoperative pulmonary complications after esophagectomy. The aim of this study was to compare this multifaceted approach (MIE-PP) and conventional thoracotomy for Ivor Lewis procedure after a systematic laparoscopic dissection.

Methods: Data from 137 consecutive patients undergoing Ivor Lewis procedures between 2010 and 2017 at two tertiary centers was analyzed retrospectively. Read More

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http://dx.doi.org/10.1007/s00464-019-06742-wDOI Listing
March 2019
1 Read

Enhanced Recovery Pathways for Cardiac Surgery.

Curr Pain Headache Rep 2019 Mar 14;23(4):28. Epub 2019 Mar 14.

Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, MA, USA.

Purpose Of Review: Enhanced recovery after surgery (ERAS) has become a widespread topic in perioperative medicine over the past 20 years. The goals of ERAS are to improve patient outcomes and perioperative experience, reduce length of hospital stay, minimize complications, and reduce cost. Interventions and factors before, during, and after surgery all potentially play a role with the cumulative effect being superior quality of patient care. Read More

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http://link.springer.com/10.1007/s11916-019-0764-2
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http://dx.doi.org/10.1007/s11916-019-0764-2DOI Listing
March 2019
2 Reads

Optimal Gating Window for Respiratory-Gated Radiotherapy with Real-Time Position Management and Respiration Guiding System for Liver Cancer Treatment.

Sci Rep 2019 Mar 13;9(1):4384. Epub 2019 Mar 13.

Department of Radiation Oncology, Yeungnam University Medical Center, Daegu, Korea.

Respiratory-gated radiotherapy is one of the most effective approaches to minimise radiation dose delivery to normal tissue and maximise delivery to tumours under patient's motion caused by respiration. We propose a respiration guiding system based on real-time position management with suitable gating window for respiratory-gated radiotherapy applied to liver cancer. Between August 2016 and February 2018, 52 patients with liver cancer received training in real-time position management and respiration guiding. Read More

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http://dx.doi.org/10.1038/s41598-019-40858-2DOI Listing
March 2019
1 Read

An Optimal Policy for Patient Laboratory Tests in Intensive Care Units.

Pac Symp Biocomput 2019 ;24:320-331

Department of Electrical Engineering, Princeton University, USA*These authors contributed equally to this work.

Laboratory testing is an integral tool in the management of patient care in hospitals, particularly in intensive care units (ICUs). There exists an inherent trade-off in the selection and timing of lab tests between considerations of the expected utility in clinical decision-making of a given test at a specific time, and the associated cost or risk it poses to the patient. In this work, we introduce a framework that learns policies for ordering lab tests which optimizes for this trade-off. Read More

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January 2019
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Risk Factors for Development of Carbapenem Resistance Among Gram-Negative Rods.

Open Forum Infect Dis 2019 Mar 23;6(3):ofz027. Epub 2019 Jan 23.

Infectious Disease Clinical Outcome Research Unit, Los Angeles Biomedical Research Institute at Harbor-UCLA, University of California, Los Angeles, Los Angeles, California.

Background: Infections due to carbapenem-resistant Gram-negative rods (CR-GNR) are increasing in frequency and result in high morbidity and mortality. Appropriate initial antibiotic therapy is necessary to reduce adverse consequences and shorten length of stay.

Methods: To determine risk factors for recovery on culture of CR-GNR, cases were retrospectively analyzed at a major academic hospital system from 2011 to 2016. Read More

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http://dx.doi.org/10.1093/ofid/ofz027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405936PMC

Pulmonary Densitovolumetry Using Computed Tomography in Patients with Nontuberculous Mycobacteria: Correlation with Pulmonary Function Tests.

Pulm Med 2019 3;2019:5942783. Epub 2019 Feb 3.

Post-Graduate Program in Medical Sciences, State University of Rio de Janeiro, Rio de Janeiro, Brazil.

Background: Since nontuberculous mycobacterial pulmonary disease (NTM-PD) is a condition with increasing morbidity, a more detailed knowledge of radiological aspects and pulmonary function plays a relevant role in the diagnosis and appropriate therapeutic management of these patients.

Objectives: The purpose of this study was to evaluate changes in lung parenchyma through computed tomography (CT) densitometry and, secondarily, to analyze its correlation with pulmonary function testing (PFT) in patients with NTM-PD.

Methods: This is a cross-sectional study in which 31 patients with NTM-PD and 27 controls matched by sex, age, and body mass index underwent CT pulmonary densitovolumetry and pulmonary function tests including spirometry and body plethysmograph. Read More

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http://dx.doi.org/10.1155/2019/5942783DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377979PMC
February 2019
1 Read

Respiratory management of acute exacerbation of interstitial pneumonia using high-flow nasal cannula oxygen therapy: a single center cohort study.

J Thorac Dis 2019 Jan;11(1):103-112

Department of Respiratory Medicine, Kobe City Medical Center General Hospital, Kobe, Hyogo, Japan.

Background: The role of high-flow nasal cannula oxygen therapy (HFNC) in respiratory management of acute exacerbation of interstitial pneumonia (AE-IP) is unknown.

Methods: We retrospectively reviewed patients with AE-IP who were admitted to our hospital from June 2009 - May 2015 and compared mortality, complications, sedatives and analgesia use, and oral intake between cohorts before (pre-HFNC: June 2009 - May 2012) and after (post-HFNC: June 2012 - May 2015) the introduction of HFNC. In the pre-HFNC cohort, standard oxygen therapy, noninvasive ventilation (NIV), and invasive mechanical ventilation (IMV) were used for respiratory management of AE-IP. Read More

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http://jtd.amegroups.com/article/view/26384/19816
Publisher Site
http://dx.doi.org/10.21037/jtd.2018.12.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384362PMC
January 2019
8 Reads

Pediatric Cancer Outcomes in an Intensive Care Unit in Pakistan.

J Glob Oncol 2019 Mar(5):1-5

1 Shaukat Khanum Memorial Cancer Hospital and Research Center, Lahore, Pakistan.

Purpose: Although cancer is uncommon, it is a significant cause of pediatric morbidity and mortality in the developing world. The need for intensive care in pediatric oncology has increased with more intense chemotherapeutic interventions. It is important to identify patients who will benefit from management in the intensive care unit (ICU), given the resource limitation in developing countries. Read More

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http://dx.doi.org/10.1200/JGO.18.00215DOI Listing
March 2019
1 Read

Concepts of Prehospital Advanced Airway Management in the Operational K9: A Focus on Cricothyrotomy.

Authors:
Lee E Palmer

J Spec Oper Med 2019 ;19(1):99-106

Similar to people, airway obstruction is a potentially preventable cause of combat and line of duty death for civilian law enforcement Operational K9s (OpK9) and military working dogs (MWD). Basic (i.e. Read More

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http://dx.doi.org/DOI Listing
January 2019

Respiratory management during therapeutic hypothermia for hypoxic-ischemic encephalopathy.

J Perinatol 2019 Mar 11. Epub 2019 Mar 11.

Department of Pediatric Newborn Medicine, Brigham and Women's Hospital, Boston, MA, USA.

Therapeutic hypothermia (TH) has become the standard of care treatment to improve morbidity and mortality in infants with hypoxic-ischemic encephalopathy (HIE). Although TH has clearly proven to be beneficial, recent studies suggest optimization of respiratory management as an approach to prevent further damage and improve neurodevelopmental outcome. The ventilatory management of asphyxiated neonates presents a challenge because both the hypoxic insult and TH have an impact on respiratory functions. Read More

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http://dx.doi.org/10.1038/s41372-019-0349-2DOI Listing
March 2019
1 Read

Impact of fluazinam on morphological and physiological characteristics of Sclerotinia sclerotiorum.

Pestic Biochem Physiol 2019 Mar 22;155:81-89. Epub 2019 Jan 22.

College of Plant Protection, Nanjing Agricultural University, Nanjing, Jiangsu 210095, China. Electronic address:

Sclerotinia sclerotiorum is a necrotrophic and filamentous fungus with a broad host range. Fluazinam is a pyridinamine fungicide with a broad spectrum of antifungal activity and had a strong inhibition effect on mycelial growth of S. sclerotiorum populations. Read More

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http://dx.doi.org/10.1016/j.pestbp.2019.01.009DOI Listing

Clinical management practices of life-threatening asthma: an audit of practices in intensive care.

Crit Care Resusc 2019 Mar;21(1):53-62

Townsville Hospital, Townsville, QLD, Australia.

Objective: Lack of management guidelines for lifethreatening asthma (LTA) risks practice variation. This study aims to elucidate management practices of LTA in the intensive care unit (ICU).

Design: A retrospective cohort study. Read More

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March 2019
2.154 Impact Factor

Contribution of root respiration to total soil respiration in a semi-arid grassland on the Loess Plateau, China.

Sci Total Environ 2018 Jun 6;627:1209-1217. Epub 2018 Feb 6.

State Key Laboratory of Grassland Agro-ecosystems, College of Pastoral Agricultural Science and Technology, Lanzhou University, P.O. Box 61, Lanzhou 730000, China; Dept. Natural Resources Management, Texas Tech University, Lubbock, TX 79409, USA.

Using the trenching method, a study was conducted in a grassland on the Loess Plateau of northern China in 2008 and 2009 to partition total soil respiration (Rt) into microbial respiration (Rm) and root respiration (Rr). Using the measurements of soil CO diffusivity and soil CO production, an analytical model was applied to correct the data, aiming to quantify the method-induced error. The results showed that Rm and Rr responded differently to biotic and abiotic factors and exhibited different diurnal and seasonal variations. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2018.01.313DOI Listing

Ability to predict team members' behaviors in ICU teams is associated with routine ABCDE implementation.

J Crit Care 2019 Mar 1;51:192-197. Epub 2019 Mar 1.

Department of Systems, Population, and Leadership, University of Michigan School of Nursing, Ann Arbor, MI, United States of America.

Purpose: Poor coordination may impede delivery of the Awakening, Breathing Coordination, Delirium monitoring/management and Early exercise/mobility (ABCDE) bundle. Developing a shared mental model (SMM), where all team members are on the same page, may support coordination.

Materials And Methods: We administered a survey at the 2016 MHA Keystone Center ICU workshop. Read More

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http://dx.doi.org/10.1016/j.jcrc.2019.02.028DOI Listing
March 2019
2 Reads

[Thoracoscopic clipping of patent ductus arteriosus: position of surgery in the era of transcatheter procedures].

Khirurgiia (Mosk) 2019 (2):5-12

Meshalkin National Medical Research Center of Healthcare Ministry of the Russian Federation, Novosibirsk, Russia.

Aim: To describe single-center evolution of the procedure and to evaluate the results of thoracoscopic clipping of patent ductus arteriosus (PDA) with diameter over 3,0 mm in term infants weighting over 4,0 kg.

Material And Methods: Thoracoscopic clipping of PDA has been performed in 140 patients for the period from March 2012 to March 2018 in Meshalkin National Medical Research Center. Mean age was 4. Read More

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http://dx.doi.org/10.17116/hirurgia20190215DOI Listing
January 2019
1 Read

Preoperative balloon pulmonary angioplasty enabled noncardiac surgery of a patient with chronic thromboembolic pulmonary hypertension (CTEPH): A case report.

Medicine (Baltimore) 2019 Mar;98(10):e14807

Department of Anesthesiology, Faculty of Medicine, The University of Tokyo, Tokyo.

Rationale: Chronic thromboembolic pulmonary hypertension (CTEPH) is a disease with a poor prognosis, characterized by chronic thromboembolic obstruction of the pulmonary arteries and pulmonary hypertension. Balloon pulmonary angioplasty (BPA) is a newly emergent treatment for CTEPH, which may substitute pulmonary endarterectomy, the standard but more invasive treatment for CTEPH. Here, we report the case of a CTEPH patient who underwent 2 noncardiac surgeries without complications after preoperative intervention of BPA. Read More

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http://Insights.ovid.com/crossref?an=00005792-201903080-0006
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http://dx.doi.org/10.1097/MD.0000000000014807DOI Listing
March 2019
1 Read

Mitochondrial dysfunction in adults after out-of-hospital cardiac arrest.

Eur Heart J Acute Cardiovasc Care 2019 Mar 11:2048872618814700. Epub 2019 Mar 11.

4 Center for Healthy Aging, University of Copenhagen, Denmark.

Background:: While preclinical studies suggest that mitochondria play a pivotal role in ischaemia-reperfusion injury, the knowledge of mitochondrial function in human out-of-hospital cardiac arrest remains scarce. The present study sought to compare oxidative phosphorylation capacity in skeletal muscle biopsies from out-of-hospital cardiac arrest patients to healthy controls.

Methods:: This was a substudy of a randomised trial comparing targeted temperature management at 33°C versus 36°C for out-of-hospital cardiac arrest patients. Read More

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http://dx.doi.org/10.1177/2048872618814700DOI Listing
March 2019
1 Read

The Characteristics and Cost of Le Fort Fractures: A Review of 519 Cases From a Nationwide Sample.

J Oral Maxillofac Surg 2019 Feb 13. Epub 2019 Feb 13.

Chairman and George Guttman Professor of Craniofacial Surgery, Section of Hospital Dentistry, Division of Oral and Maxillofacial Surgery, NewYork-Presbyterian/Columbia University Irving Medical Center, Columbia University College of Dental Medicine, New York, NY.

Purpose: The aims were to report the characteristics of Le Fort fractures and to quantify the associated hospital costs.

Materials And Methods: From October 2015 to December 2016, the National Inpatient Sample was searched for patients admitted with a primary diagnosis of a Le Fort fracture. Predictor variables were drawn from demographic, admission, and injury characteristics. Read More

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http://dx.doi.org/10.1016/j.joms.2019.01.060DOI Listing
February 2019
1 Read
1.280 Impact Factor

Good infection prevention practices in three Brazilian hospitals: Implications for patient safety policies.

J Infect Public Health 2019 Mar 7. Epub 2019 Mar 7.

Curso de Gestão em Sistemas e Serviços de Saúde, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.

Objective: Healthcare-associated infections (HAI) are a serious patient safety problem. There are effective preventive practices, but little information on adherence in Brazilian hospitals. This study aims at assessing adherence to good HAI prevention practices. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18760341193008
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http://dx.doi.org/10.1016/j.jiph.2019.02.016DOI Listing
March 2019
3 Reads

Chlorhexidine-Related Mortality Rate in Critically Ill Subjects in Intensive Care Units: A Systematic Review and Meta-Analysis.

Respir Care 2019 Mar;64(3):337-349

Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada.

Background: This meta-analysis aimed to explore the chlorhexidine-related mortality rate for subjects on mechanical ventilation and in an ICU when compared with subjects who received standard ICU care.

Methods: We searched a number of medical literature databases and the first 100 results in an internet search. Two of us independently reviewed the titles and abstracts of the identified articles. Read More

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http://dx.doi.org/10.4187/respcare.06434DOI Listing
March 2019
1 Read

Procedural and Clinical Outcomes in Management of Bifurcational Lesions in ST Elevation Myocardial Infarction.

Heart Lung Circ 2019 Feb 6. Epub 2019 Feb 6.

Monash Heart, Monash Medical Centre, Melbourne, Vic, Australia.

Background: Bifurcation percutaneous coronary intervention (PCI) remains a challenging frontier in interventional cardiology, especially in the setting of ST-elevation myocardial infarction (STEMI). We examined the procedural and clinical outcomes of this patient subset.

Methods: We conducted a retrospective case-control study. Read More

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http://dx.doi.org/10.1016/j.hlc.2019.01.011DOI Listing
February 2019
1 Read

Bridging energy performance gaps of green office buildings via more targeted operations management: A system dynamics approach.

J Environ Manage 2019 Mar 5;238:64-71. Epub 2019 Mar 5.

Architectural Design and Research Institute of Tsinghua University, Haidian District, Beijing, 100084, PR China; Department of Building Science and Technology, Tsinghua University, Haidian District, Beijing, 100084, PR China.

In China, one of the major causes of energy performance gaps observed in green office buildings is the incompetent operations management, which is not distinguished from that of traditional buildings on both facilities and occupants. In this paper, a system dynamics model was established to simulate the interactions (primarily through communications) between facility managers and occupants and to find out targeted operations management strategies to narrow energy performance gaps. The model identifies different types of occupants and uses the Monte Carlo method to address the uncertainty between energy consumption and indoor environment quality satisfaction of occupants. Read More

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http://dx.doi.org/10.1016/j.jenvman.2019.02.111DOI Listing

Risk factors for respiratory failure in Guillain-Barré syndrome in Bangladesh: a prospective study.

Ann Clin Transl Neurol 2019 Feb 7;6(2):324-332. Epub 2019 Jan 7.

National Institute of Neurosciences and Hospital Dhaka Bangladesh.

Objective: We investigated clinical, biological, and electrophysiological risk factors for mechanical ventilation (MV) and patient outcomes in Bangladesh using one of the largest, prospective Guillain-Barré syndrome (GBS) cohorts in developing world.

Methods: A total of 693 GBS patients were included in two GBS studies conducted between 2006 and 2016 in Dhaka, Bangladesh. Associations between baseline characteristics and MV were tested using Fisher's exact test, χ test, or Mann-Whitney -test, as appropriate. Read More

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http://dx.doi.org/10.1002/acn3.706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389747PMC
February 2019
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Pediatric Donor Management Goals in Use by US Organ Procurement Organizations.

Prog Transplant 2019 Mar 7:1526924819835835. Epub 2019 Mar 7.

2 Department of Internal Medicine, Center for Outcomes Research, Saint Louis University, St Louis, MO, USA.

Introduction:: A recent study of pediatric organ donation after the neurologic determination of death (DNDD) demonstrated an association between the use of donor management goals (DMGs) by organ procurement organizations (OPOs) and organ yield.

Objective:: To describe the pediatric DMGs used by OPOs and any association between specific DMGs and organ yield.

Design:: Query of US OPOs who utilized DMGs in the care of pediatric DNDD organ donors from 2010 to 2013. Read More

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http://dx.doi.org/10.1177/1526924819835835DOI Listing
March 2019
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Artificial Intelligence-Assisted Heating Ventilation and Air Conditioning Control and the Unmet Demand for Sensors: Part 1. Problem Formulation and the Hypothesis.

Sensors (Basel) 2019 Mar 6;19(5). Epub 2019 Mar 6.

Department of Energy and Refrigerating Air-Conditioning Engineering, National Taipei University of Technology, Taipei 10608, Taiwan.

In this study, information pertaining to the development of artificial intelligence (AI) technology for improving the performance of heating, ventilation, and air conditioning (HVAC) systems was collected. Among the 18 AI tools developed for HVAC control during the past 20 years, only three functions, including weather forecasting, optimization, and predictive controls, have become mainstream. Based on the presented data, the energy savings of HVAC systems that have AI functionality is less than those equipped with traditional energy management system (EMS) controlling techniques. Read More

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http://dx.doi.org/10.3390/s19051131DOI Listing

[Analysis on the standardized management of hospitalized asthmatic patients: a single center 10-years experience].

Zhonghua Jie He He Hu Xi Za Zhi 2019 Mar;42(3):179-184

Center of Respiratory Medicine and Allergic Diseases, the General Hospital of Northern Military District, Shenyang 110016, China.

To analyze the outcome of standardized management on the hospitalized asthmatic patients in the past 10 years in a single center. Clinical data of 2 207 asthmatic patients, who were hospitalized in the Center of Respiratory Medicine and Allergic Diseases, the General Hospital of Northern Military District from January 1, 2008 to December 31, 2017, was retrospectively collected and analyzed. Asthmatic in-patients accounted for 11. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1001-0939.2019.03.007DOI Listing
March 2019
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Epigenetic loss of the endoplasmic reticulum-associated degradation inhibitor SVIP induces cancer cell metabolic reprogramming.

JCI Insight 2019 Mar 7;5. Epub 2019 Mar 7.

The endoplasmic reticulum (ER) of cancer cells needs to adapt to the enhanced proteotoxic stress associated with the accumulation of unfolded, misfolded and transformation-associated proteins. One way by which tumors thrive in the context of ER stress is by promoting ER-Associated Degradation (ERAD), although the mechanisms are poorly understood. Here, we show that the Small p97/VCP Interacting Protein (SVIP), an endogenous inhibitor of ERAD, undergoes DNA hypermethylation-associated silencing in tumorigenesis to achieve this goal. Read More

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http://dx.doi.org/10.1172/jci.insight.125888DOI Listing

Prediction of Liver Fibrosis Using CT Under Respiratory Control: New Attempt Using Deformation Vectors Obtained by Non-rigid Registration Technique.

Anticancer Res 2019 Mar;39(3):1417-1424

Department of Clinical Radiology Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Aim: To investigate whether liver fibrosis can be predicted by quantifying the deformity of the liver obtained based on computed tomographic (CT) images scanned under respiratory control.

Materials And Methods: For dynamic CT of 47 patients, portal venous and equilibrium phases were scanned during inspiration and expiration, respectively. After rigid registration of the two images, non-rigid registration of the liver was performed, and the amount and direction of each voxel's shift during non-rigid registration was defined as the deformation vector. Read More

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http://ar.iiarjournals.org/lookup/doi/10.21873/anticanres.13
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http://dx.doi.org/10.21873/anticanres.13257DOI Listing
March 2019
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Climate warming and tree carbon use efficiency in a whole-tree CO tracer study.

New Phytol 2019 Mar 6. Epub 2019 Mar 6.

Hawkesbury Institute for the Environment, Western Sydney University, Penrith, NSW, 2751, Australia.

Autotrophic respiration is a major driver of the global C cycle and may contribute a positive climate warming feedback through increased atmospheric concentrations of CO . The extent of this feedback depends on plants' ability to acclimate respiration to maintain a constant carbon use efficiency (CUE). We quantified respiratory partitioning of gross primary production (GPP) and CUE of field-grown trees in a long-term warming experiment (+3°C). Read More

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http://dx.doi.org/10.1111/nph.15721DOI Listing
March 2019
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Update in Electrical Storm Therapy.

Am J Ther 2019 Mar/Apr;26(2):e257-e267

Heart and Vascular Center, Semmelweis University, Budapest, Hungary.

Background: Electrical storm (ES) is a major life-threatening event, which announces a possible negative outcome and poor prognosis and poses challenging questions concerning etiology and management.

Data Sources: A literature search was conducted through MEDLINE and EMBASE (past 30 years until the end of September 2018) using the following search terms: ES, ventricular fibrillation, ventricular tachycardia, ablation, and implantable defibrillator. Clinicaltrials. Read More

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http://dx.doi.org/10.1097/MJT.0000000000000918DOI Listing
March 2019
3 Reads

Therapeutic Advances in the Management of Cardiogenic Shock.

Am J Ther 2019 Mar/Apr;26(2):e234-e247

University of Medicine "Carol Davila," Bucharest.

Background: Cardiogenic shock (CS) is a life-threatening state of tissue hypoperfusion, associated with a very high risk of mortality, despite intensive monitoring and modern treatment modalities. The present review aimed at describing the therapeutic advances in the management of CS.

Areas Of Uncertainty: Many uncertainties about CS management remain in clinical practice, and these relate to the intensity of invasive monitoring, the type and timing of vasoactive therapies, the risk-benefit ratio of mechanical circulatory support (MCS) therapy, and optimal ventilation mode. Read More

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http://dx.doi.org/10.1097/MJT.0000000000000920DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404765PMC
March 2020
2 Reads

Survey of the Current Use of Dexmedetomidine and Management of Withdrawal Symptoms in Critically Ill Children.

J Pediatr Pharmacol Ther 2019 Jan-Feb;24(1):16-21

Objectives: Dexmedetomidine use for sedation in the pediatric intensive care units (PICUs) has increased since its initial US Food and Drug Administration (FDA) approval in adults. However, there is limited evidence to direct providers regarding current usage, dosing, and monitoring for withdrawal symptoms in pediatric patients. This study sought to determine the utilization of dexmedetomidine and management of dexmedetomidine withdrawal symptoms among PICU physicians. Read More

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http://dx.doi.org/10.5863/1551-6776-24.1.16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397011PMC
March 2019
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The new application of point-of-care lung ultrasound in guiding or assisting neonatal severe lung disease treatment based on a case series.

J Matern Fetal Neonatal Med 2019 Mar 5:1-211. Epub 2019 Mar 5.

a Department of Neonatology and NICU , Beijing Chaoyang District Maternal and Child Healthcare Hospital , Beijing , China.

Lung ultrasound (LUS) has been successfully used for neonatal lung disease diagnosis, as a noninvasive, free of radiation tool, it is easy to operate and can be performed at the bedside within the neonatal intensive care unit (NICU), the application of point of care LUS (POC-LUS) to diagnose lung disease has become a new trend worldwide. In addition to the diagnosis of lung diseases, LUS can also be used to guide or assist the neonatal lung diseases management and has already achieved excellent effects, such as guiding the application of mechanical ventilation and exogenous pulmonary surfactant, assisting neonatal pulmonary disease treatment, etc., these technologies would be introduced in this paper to improve their application clinically. Read More

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http://dx.doi.org/10.1080/14767058.2019.1590332DOI Listing
March 2019
3 Reads

Amniotic fluid volume at presentation with early preterm premature rupture of the membranes and the association with severe neonatal respiratory morbidity.

Ultrasound Obstet Gynecol 2019 Mar 4. Epub 2019 Mar 4.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada.

Objective: Amniotic fluid volume (AFV) plays an important role in early fetal lung development, and oligohydramnios in early pregnancy has been associated with pulmonary hypoplasia. We aimed to evaluate the association between AFV at the time of presentation with early preterm premature rupture of membranes (PPROM) and severe neonatal respiratory morbidity and other adverse pregnancy outcomes.

Methods: We performed a retrospective study of all women with a singleton pregnancy admitted to a single tertiary referral center between 2004-2014 for expectant management of PPROM at 20 -28 weeks' gestation. Read More

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http://dx.doi.org/10.1002/uog.20257DOI Listing
March 2019
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