23,903 results match your criteria Ventilation Management


Clinical Management of Adult Patients with COVID-19 Outside Intensive Care Units: Guidelines from the Italian Society of Anti-Infective Therapy (SITA) and the Italian Society of Pulmonology (SIP).

Infect Dis Ther 2021 Jul 30. Epub 2021 Jul 30.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.

Introduction: The Italian Society of Anti-Infective Therapy (SITA) and the Italian Society of Pulmonology (SIP) constituted an expert panel for developing evidence-based guidance for the clinical management of adult patients with coronavirus disease 2019 (COVID-19) outside intensive care units.

Methods: Ten systematic literature searches were performed to answer ten different key questions. The retrieved evidence was graded according to the Grading of Recommendations Assessment, Development, and Evaluation methodology (GRADE). Read More

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[ORGANIZATION OF MEDICAL REHABILITATION OF PATIENTS WITH COVID-19 IN THE POST-HOSPITAL PERIOD].

Probl Sotsialnoi Gig Zdravookhranenniiai Istor Med 2021 Jun;29(Special Issue):598-602

Pirogov Russian National Research Medical University, 117997, Moscow, Russia.

The COVID-19 pandemic poses new challenges for the health sector, related to the organization of medical rehabilitation of patients with COVID-19. Special attention is required for patients after artificial ventilation, who have a high risk of developing physical, mental and cognitive disorders. There are acute post-ovoid syndrome lasting more than 3 weeks and chronic-lasting more than 12 weeks after discharge from the hospital. Read More

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Reversibility of total airway closure and alveolar consolidation in a COVID-19 patient: A case study.

Nurs Crit Care 2021 Jul 29. Epub 2021 Jul 29.

Department of Medical and Toxicological Critical Care, Lariboisière Hospital, APHP, Paris, France.

Coronavirus disease 2019 (COVID-19) may be complicated by life-threatening pneumonia requiring tracheal intubation, mechanical ventilation and veno-venous extracorporeal membrane oxygenation (vvECMO). It is not yet clear to what extent and after which delay the most severe cases of COVID-19 pneumonia are reversible. Here, we present a 39-year-old patient who developed a severe COVID-19-attributed acute respiratory distress syndrome (ARDS) resulting in complete alveolar consolidation and airway closure for several weeks. Read More

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Treatment of Severe Hypercapnic Respiratory Failure Caused by SARS-CoV-2 Lung Injury with ECCOR Using the Hemolung Respiratory Assist System.

Case Rep Crit Care 2021 29;2021:9958343. Epub 2021 Jun 29.

Minneapolis Heart Institute Foundation, Minneapolis, MN 55407, USA.

Acute respiratory distress syndrome (ARDS) due to COVID-19 leads to a high rate of mortality in the intensive care unit (ICU). A lung-protective mechanical ventilation strategy using low tidal volumes is a cornerstone to management, but uncontrolled hypercapnia is a life-threatening consequence among severe cases. A mechanism to prevent progressive hypercapnia may offset hemodynamic instability among patients who develop hypercapnia. Read More

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SARS-CoV-2 airborne transmission: A validated sampling and analytical method.

Environ Res 2021 Jul 26:111783. Epub 2021 Jul 26.

Dept. of Clinical and Biological Science, University of Torino, Regione Gonzole 10, 10043, Orbassano, Torino, Italy.

The airborne transmission path for SARS-CoV-2 is of primary scientific and health-related interest as it could actually involve management, accessibility, use and functionality of many activities, including hospitals), schools, workplaces, factories, transport, sport venues and outdoor environment. It is necessary to develop a sampling and analytical method for virus-laden bioaerosol that could be considered reliable and validated according to ISO/IEC 17025 requirements. The present paper defines sample pretreatments aiming at recover SARS-CoV-2 from glass-fiber and PTFE filters employed by low and high-volume air samplers. Read More

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Trends in COVID-19 cases and clinical management in Veterans Health Administration medical facilities: A national cohort study.

PLoS One 2021 29;16(7):e0246217. Epub 2021 Jul 29.

White River Junction Veterans Affairs Medical Center, White River Junction, Vermont, United States of America.

Objective: We explored longitudinal trends in sociodemographic characteristics, reported symptoms, laboratory findings, pharmacological and non-pharmacological treatment, comorbidities, and 30-day in-hospital mortality among hospitalized patients with coronavirus disease 2019 (COVID-19).

Methods: This retrospective cohort study included patients diagnosed with COVID-19 in the United States Veterans Health Administration between 03/01/20 and 08/31/20 and followed until 09/30/20. We focused our analysis on patients that were subsequently hospitalized, and categorized them into groups based on the month of hospitalization. Read More

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Evaluation of Bivalirudin as the Primary Anticoagulant in Patients Receiving Extracorporeal Membrane Oxygenation for SARS-CoV-2-Associated Acute Respiratory Failure.

Ann Pharmacother 2021 Jul 29:10600280211036151. Epub 2021 Jul 29.

University of Kentucky, Lexington, KY, USA.

Background: Extracorporeal membrane oxygenation (ECMO) is a potential option for the management of severe acute respiratory failure secondary to COVID-19. Conflicting the use of this therapy is the known coagulopathy within COVID-19, leading to an incidence of venous thrombotic events of 25% to 49%. To date, limited guidance is available on optimal anticoagulation strategies in this population. Read More

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The role of noninvasive ventilation in the management of type II respiratory failure in patients with myotonic dystrophy.

ERJ Open Res 2021 Jul 26;7(3). Epub 2021 Jul 26.

North West Ventilation Unit, Manchester University NHS Foundation Trust, Manchester, UK.

Type 1 myotonic dystrophy (DM1) causes sleep disordered breathing and respiratory failure due to a combination of obstructive sleep apnoea, reduced central drive and respiratory muscle weakness. Noninvasive ventilation (NIV) is commonly used for treating respiratory failure in neuromuscular disease; however, there have been few studies assessing the role of NIV in DM1. The aim of this retrospective service evaluation was to investigate the impact of NIV adherence on hypercapnia and symptoms of hypoventilation in patients with DM1. Read More

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Hospitalization, Mechanical Ventilation, and Mortality After COVID-19 Among Adults With or Without Serious Mental Illness.

Psychiatr Serv 2021 Jul 29:appips202100151. Epub 2021 Jul 29.

Division of General Internal Medicine, Johns Hopkins School of Medicine, Baltimore (Murphy, Daumit); Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Medical Institutions, Baltimore (Murphy); Department of Health Policy and Management (McGinty), and Department of Mental Health (McGinty, Daumit), Johns Hopkins Bloomberg School of Public Health, Baltimore.

Objective: The authors evaluated the likelihood of hospital admission, mechanical ventilation, and mortality within 30 days after a COVID-19 diagnosis among persons with or without serious mental illness.

Methods: Adults with and without serious mental illness diagnosed as having COVID-19 in the first year of the pandemic were identified in the TriNetX database, a network of electronic health records from 49 U.S. Read More

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Tough transitions: Family caregiver experiences with a pediatric long-term ventilation discharge pathway.

Pediatr Pulmonol 2021 Jul 28. Epub 2021 Jul 28.

Hospital for Sick Children, Toronto, Ontario, Canada.

Objectives: Discharging a child home on long-term ventilation (LTV) via tracheostomy is complex and involves multiple healthcare providers across healthcare sectors. To date, there has been a paucity of data with respect to the experiences of families transitioning a child home on LTV. Our objective was to explore the perceptions of family caregivers (FCs) who have completed a newly developed LTV discharge pathway as they transitioned home. Read More

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Difference in the Care of Patients with Amyotrophic Lateral Sclerosis With and Without Intervention from the Palliative Care Team: Observations from a Center in Japan.

Palliat Med Rep 2021 2;2(1):201-206. Epub 2021 Jul 2.

Department of Neurology, Hokuriku Brain and Neuromuscular Disease Center, National Hospital Organization Iou National Hospital, Kanazawa, Japan.

Despite the significant palliative care needs for people living with amyotrophic lateral sclerosis (ALS), palliative medicine in Japan is mainly focused on oncologic disease. To compare the care provided to patients with ALS with and without intervention from the palliative care team (PCT and non-PCT groups, respectively). This is a retrospective case-control study. Read More

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Associations between oxygen delivery and cardiac index with hyperlactatemia during cardiopulmonary bypass.

JTCVS Tech 2020 Jun 13;2:92-99. Epub 2020 Apr 13.

Department of Cardiac Surgery, Anthea Hospital, GVM Care & Research, Bari, Italy.

Objective: Metabolism management plays an essential role during cardiopulmonary bypass (CPB). There are different metabolic management devices integrated to heart-lung machines; the most commonly used and accepted metabolic target is indexed oxygen delivery (DO) (280 mL/min/m) and cardiac index (CI) (2.4 L/min/m), which can be managed independently or according to other metabolic parameters. Read More

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Role of Invasive Mechanical Ventilation and ECMO in the Management of COVID-19: A Systematic Review.

Indian J Crit Care Med 2021 Jun;25(6):691-698

Centre for Trials Research, College of Biomedical and Life Sciences, Cardiff University, Cardiff, Wales, United Kingdom.

Objectives: This systematic review aims to provide insight into the outcome of extracorporeal membrane oxygenation (ECMO) and invasive mechanical ventilation use in critically ill COVID-19 patients.

Data Sources: Electronic databases PubMed Central and PubMed were searched from January 2020 to June 2020 for published studies about ECMO and/or invasive mechanical ventilation use in COVID-19 patients. Data Extraction and Study Selection: The search strategy retrieved 766 articles, of which 19 studies consisting of 204 patients fulfilled the inclusion criteria and were included in the analysis. Read More

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Feasible and effective use of a simulation-based curriculum for post-graduate emergency medicine trainees in India to improve learner self-efficacy, knowledge, and skills.

Int J Emerg Med 2021 Jul 27;14(1):42. Epub 2021 Jul 27.

George Washington University School of Medicine and Public Health, Washington DC, USA.

Background: Pediatric emergency medicine training is in its infancy in India. Simulation provides an educational avenue to equip trainees with the skills to improve pediatric care. We hypothesized that a simulation-based curriculum can improve Indian post-graduate emergency medicine (EM) trainees' self-efficacy, knowledge, and skills in pediatric care. Read More

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Device Profile of the Zephyr Endobronchial Valve in Heterogenous Emphysema: Overview of its Safety and Efficacy.

Expert Rev Med Devices 2021 Jul 27. Epub 2021 Jul 27.

Department of Thoracic Medicine and Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.

Introduction: Emphysema affects millions of people in the United States; the underlying pathophysiology is destruction of lung parenchyma resulting in hyperinflation. To date mainstay of treatment is medical care however currently there are 2 surgical treatment strategies approved by the FDA to reduce lung hyperinflation. First being lung volume reduction surgery (LVRS) which carries significant higher risk of mortality within 90 days of the procedure versus bronchoscopic lung volume reduction surgery (BLVR). Read More

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A telerehabilitation programme in post-discharge COVID-19 patients (TERECO): a randomised controlled trial.

Thorax 2021 Jul 26. Epub 2021 Jul 26.

Institute for Disaster Management and Reconstruction, Sichuan University, Chengdu, Sichuan, People's Republic of China

Objectives: To investigate superiority of a telerehabilitation programme for COVID-19 (TERECO) over no rehabilitation with regard to exercise capacity, lower limb muscle strength (LMS), pulmonary function, health-related quality of life (HRQOL) and dyspnoea.

Design: Parallel-group randomised controlled trial with 1:1 block randomisation.

Setting: Three major hospitals from Jiangsu and Hubei provinces, China. Read More

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COVID-19 Clinical Phenotypes and Short-term Outcomes: Differences Between the First and the Second Wave of Pandemic in Italy.

Expert Rev Respir Med 2021 Jul 27. Epub 2021 Jul 27.

Institute of Respiratory Disease, Department of Basic Medical Science, Neuroscience, and Sense Organs, University of Bari, "Aldo Moro", Bari.

Objectives: There are no comparison studies between patients belonging to the first and second waves of the pandemic of the SARS-CoV-2, the virus triggering coronavirus disease 2019 (COVID-19). In this retrospective observational study, we analyzed clinical characteristics and the short-term outcomes of two groups of laboratory-confirmed COVID-19 patients with moderate-to-severe acute respiratory distress syndrome (ARDS) belonging to two different waves of the pandemic.

Methods: We analyzed 97 consecutive patients from 11 March, 2020 to 31 May, 2020 and 52 consecutive patients from 28 August, 2020 to 15 October, 2020. Read More

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Risk factors for mortality in critically ill infants with acute kidney injury: A resource- limited setting experience.

Ther Apher Dial 2021 Jul 22. Epub 2021 Jul 22.

Division of Pediatric Nephrology, Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

Introduction: Infants with acute kidney injury (AKI) are critically ill often will have multiorgan dysfunctions. Objective of the present study was to find out mortality, recovery of kidney function at discharge and at 3 months and to determine risk factors for mortality.

Methods: Fifty-two infants (24- newborns and 28 post-neonatal) with AKI were included. Read More

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Clinical features and outcomes of critically ill patients with Elizabethkingia meningoseptica: an emerging pathogen.

Acute Crit Care 2021 Jul 26. Epub 2021 Jul 26.

Section of Infectious Diseases, Department of Medicine, Aga Khan University, Karachi, Pakistan.

Background: Elizabethkingia meningoseptica, formerly known as Chryseobacterium meningosepticum, is a non-motile, non-fastidious, catalase and oxidase-positive, aerobic, glucose-non-fermentative, Gram-negative bacillus that was first defined by Elizabeth O. King in 1959. It has emerged as an opportunistic pathogen that has infected patients in extreme age groups and immunocompromised individuals, especially in intensive care settings. Read More

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Life with pediatric home ventilation: Expectations versus experience.

Pediatr Pulmonol 2021 Jul 26. Epub 2021 Jul 26.

Johns Hopkins Berman Institute of Bioethics, Baltimore, Maryland, USA.

Objectives: To explore the family experience of home ventilation through a comparison of anticipated home life changes with subsequent experiences.

Study Design: Guided interviews with parents across three states who chose home ventilation for their child within the last 5 years.

Patient-subject Selection: Purposive sampling of parents who chose home ventilation for their child within the last 5 years. Read More

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Handling oxygenation targets in ICU patients with COVID-19 - protocol and statistical analysis plan in the HOT-COVID trial.

Acta Anaesthesiol Scand 2021 Jul 26. Epub 2021 Jul 26.

Department of Anaesthesia and Intensive Care, Aalborg University Hospital, Aalborg, Denmark.

Background: Coronavirus disease (COVID-19) primarily affects the lungs and lower airways and may present as hypoxaemic respiratory failure requiring admission to an intensive care unit (ICU) for supportive treatment. Here, supplemental oxygen remains essential for COVID-19 patient management, but the optimal dosage is not defined. We hypothesise that targeting an arterial partial pressure of oxygen of 8 kPa throughout ICU admission is superior to targeting 12 kPa. Read More

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Coronavirus disease 2019 respiratory failure: what is the best supportive care for patients who require ICU admission?

Curr Opin Crit Care 2021 Jul 22. Epub 2021 Jul 22.

Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of California, San Diego, La Jolla, California, USA.

Purpose Of Review: Currently, there is no cure for SARS-CoV-2 infection, yet hospital mortality rates for COVID-19 have improved over the course of the pandemic and may be due in part to improved supportive care in the ICU. This review highlights the evidence for and against various ICU supportive therapies for the treatment of critically ill patients with COVID-19.

Recent Findings: Early in the pandemic, there was great interest in novel ICU supportive care, both for the benefit of the patient, and the safety of clinicians. Read More

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Risk Factors and Outcomes Associated with Community-Onset and Hospital-Acquired Co-infection in Patients Hospitalized for COVID-19: A Multi-Hospital Cohort Study.

Infect Control Hosp Epidemiol 2021 Jul 26:1-28. Epub 2021 Jul 26.

Internal Medicine, Division of Infectious Diseases, University of Michigan, Ann Arbor, MI, USA.

Background: We sought to determine the incidence of community-onset and hospital-acquired co-infection in patients hospitalized with COVID-19 and evaluate associated predictors and outcomes.

Methods: Multicenter retrospective cohort study of patients hospitalized for COVID-19, 3/2020 to 8/2020, across 38 Michigan hospitals assessed for prevalence, predictors, and outcomes of community-onset or hospital-acquired co-infection. In-hospital and 60-day mortality, readmission, discharge to long-term care facility (LTCF), and mechanical ventilation duration, were assessed for patients with vs. Read More

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Clinical characteristics and outcomes of patients with heart failure admitted to the intensive care unit with coronavirus disease 2019 (COVID-19): A multicenter cohort study.

Am Heart J Plus 2021 Jul 19;7:100033. Epub 2021 Jul 19.

Department of Pharmacy Practice, College of Pharmacy, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Department of Pharmaceutical Care Services, King Abdulaziz Medical City, Riyadh, Saudi Arabia.

Background: Patients with underlying heart failure (HF) in the setting of COVID-19 who require admission to the intensive care unit (ICU) might present with a unique set of challenges. This study aims to extensively describe the characteristics and outcomes of patients with HF who were admitted to ICU with COVID-19.

Methods: We conducted a multicenter retrospective analysis for all adult patients with HF and an objectively confirmed diagnosis of COVID-19 who were admitted to ICUs between March 1 and August 31, 2020, in Saudi Arabia. Read More

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Characteristics and Safety of CO for the Fire Prevention Technology with Gob-Side Entry Retaining in Goaf.

ACS Omega 2021 Jul 8;6(28):18518-18526. Epub 2021 Jul 8.

School of Economics and Management, North China Institute of Science and Technology, Beijing 101601, China.

The mining technology of gob-side entry retaining without a coal pillar is gradually becoming a mature and increasingly important mining technology. As it maintains the roadway near goaf, the air leakage should be greater than a U-type ventilation system in goaf, so it is prone to cause coal spontaneous combustion problems. CO is an inert gas, and it is usually used to prevent spontaneous combustion and extinguish coal fire. Read More

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Self-learning on COVID-19 among medical students in Bhutan: A cross-sectional study.

Heliyon 2021 Jul 11;7(7):e07533. Epub 2021 Jul 11.

Department of Internal Medicine, Armed Forces Medical College, Maharashtra University of Health Sciences, Pune, India.

Background: Bhutan lacks a medical school and all medical students are trained in Sri Lanka, Bangladesh and India. When the COVID-19 pandemic led to the closure of medical schools in these countries in March-April 2020, the medical students were repatriated to Bhutan. Upon return, they were kept in government-sponsored facility quarantine for 21 days. Read More

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Ventilation and air-conditioning systems in dental clinics and COVID-19: How much do we know?

J Clin Exp Dent 2021 Jul 1;13(7):e692-e700. Epub 2021 Jul 1.

Faculty of Dentistry. University of Antioquia, Medellin, Colombia.

Background: This study evaluated the association between knowledge and management of ventilation and air-conditioning systems (VAC) to avoid the spread of the SARS-CoV-2 virus in health facilities by dentists and demographic variables.

Material And Methods: A cross-sectional digital media survey was administered to dentists as part of global research. The core questionnaire was used including four additional questions on VAC (Q1: knowledge, Q2: work settings, Q3: temperature, and Q4: maintenance). Read More

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Application and significance of PiCCO monitoring technique combined with troponin I detection in fluid resuscitation of elderly patients with septic myocardial dysfunction.

Am J Transl Res 2021 15;13(6):6846-6854. Epub 2021 Jun 15.

Department of Critical Care Medicine, Changzhou Fourth People's Hospital Changzhou 213000, Jiangsu Province, China.

Objective: This study was designed to demonstrate the predictive value of Pulse indicate Contour Cardiac Output (PiCCO) monitoring technique combined with troponin I (cTnI) detection in septic myocardial dysfunction (SMD) of the elderly.

Methods: One hundred and nineteen elderly patients with SMD treated in our hospital from March 2016 to September 2019 were enrolled and allocated into the joint group (JG; 64 cases) for capacity management of fluid resuscitation under the guidance of PiCCO monitoring technique and cTnI detection, and the control group (CG; 55 cases) for conventional capacity management. Clinical indicators, hemodynamics, improvement of myocardial injury markers and inflammatory factors 6 h and 36 h post intervention, fluid balance 6 h, 12 h and 36 h post intervention, drug consumption (norepinephrine), treatment effect and 28-day hospitalization mortality were compared between the two groups. Read More

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Comparative analysis of ventilation efficiency on ultrafine particle removal in university MakerSpaces.

Atmos Environ (1994) 2020 Mar 6;224. Epub 2020 Feb 6.

Department of Chemical and Life Science Engineering, Virginia Commonwealth University, 601 W. Main St, Richmond, VA, 23284, United States.

The proliferation of 3D printing MakerSpaces in university settings has led to an increased risk of student and technician exposure to ultrafine particles. New MakerSpaces do not have standardized specifications to aid in the design of the space; therefore, a need exists to characterize the impacts of different engineering controls on MakerSpace air quality. This study compares three university MakerSpaces: a library MakerSpace operating ≤4 devices under typical office space ventilation with no engineering controls, a laboratory MakerSpace operating 29 printers inside grated cabinets, with laboratory-grade ventilation, and a center MakerSpace operating ≤4 devices with neither engineering controls nor internal ventilation. Read More

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[Critical patients COVID-19 Has changed the management and outcomes in the ICU after 1 year of the pandemic?A multicenter, prospective, observational study].

Enferm Infecc Microbiol Clin 2021 Jul 19. Epub 2021 Jul 19.

The Preventive Medicine and Public Health Sciences, University of A Coruña, Spain.

Objective: To compare the clinical characteristics, treatments, and evolution of critical patients with COVID-19 pneumonia treated in Intensive Care Units (ICU) after one year of pandemic.

Methodology: Multicenter, prospective study, which included critical COVID-19 patients in 9 ICUs in northwestern Spain. The clinical characteristics, treatments, and evolution of patients admitted to the ICU during the months of March-April 2020 (period 1) were compared with patients admitted in January-February 2021 (period 2). Read More

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