418,685 results match your criteria Venous Lakes


Prospective study of clinical, neurophysiological and urodynamic findings in multiple scleosis patients undergoing percutaneous transluminal venous angioplasty.

Clin Neurophysiol 2018 Nov 26;130(1):138-144. Epub 2018 Nov 26.

Department of Medicine, Surgery and Neuroscience, Unit of Neurology and Clinical Neurophysiology, University of Siena, Italy. Electronic address:

Objective: Verify whether Percutaneous Transluminal Angioplasty (PTA) may affect neural conduction properties in Multiple Sclerosis (MS) patients, thereby modifying patients' disability, with prospective neurophysiological, urodynamic, clinical and subjective well-being evaluations.

Methods: In 55 out of 72 consecutively screened MS patients, the following procedures were carried out before (T0), at 2-6 months (T1) and at 6-15 months (T2) after a diagnostic phlebography, eventually followed by the PTA intervention if chronic cerebrospinal venous insufficiency (CCSVI) was diagnosed: clinical/objective evaluation (Expanded Disability Status Scale, EDSS), ratings of subjective well-being, evaluation of urodynamic functions and multimodal EPs (visual, acoustic, upper and lower limbs somatosensory and motor evoked potentials).

Results: The number of dropouts was relatively high, and a complete set of neurophysiological and clinical data remained available for 37 patients (19 for urological investigations). Read More

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November 2018

Adalimumab efficacy for venous thrombosis in typical sites in Behçet's syndrome.

Arthritis Rheumatol 2018 Dec 7. Epub 2018 Dec 7.

Department of Neurosciences, Psychology, Pharmacology and Child Health (NEUROFARBA), University of Firenze, Italy.

In our work entitled "Adalimumab-based treatment versus DMARDs for venous thrombosis in Behçet syndrome. A retrospective study of 70 patients with vascular involvement" , we showed that Adalimumab (ADA)-based regimen is more effective and rapid than disease modifying anti-rheumatic drugs (DMARDs) in inducing resolution of venous thrombosis in patients with Behçet syndrome (BS), also allowing significant reduction of steroid exposure. This article is protected by copyright. Read More

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December 2018

Eight-week interval in flushing and locking port-a-cath in cancer patients: A single-institution experience and systematic review.

Eur J Cancer Care (Engl) 2018 Dec 10:e12978. Epub 2018 Dec 10.

Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, Medical Oncology, University of Brescia at ASST Spedali Civili, Brescia, Italy.

Port-a-cath (PAC) system is one of the most frequently employed venous accesses for administration of chemotherapy and supportive care. To prevent late complications, the latest guidelines recommend flushing/locking procedures every four weeks. In this retrospective study, we evaluate the frequencies of late complications with a eight-week flushing/locking procedure compared to the standard one. Read More

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December 2018

Venous thromboembolism in head and neck surgery: Risk, outcome, and burden at the national level.

Head Neck 2018 Dec 7. Epub 2018 Dec 7.

Department of Surgery, Tulane University School of Medicine, New Orleans, Louisiana.

Background: Venous thromboembolism (VTE) can complicate major surgeries. This study examines the risk and outcomes of VTE in patients who underwent head and neck surgeries.

Methods: Retrospective cross-sectional analysis utilizing the Nationwide Readmissions Database (2010-2014). Read More

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December 2018

Spontaneous pulmonary air embolism in a child undergoing procedural deep sedation: case report and review of the literature.

Eur Rev Med Pharmacol Sci 2018 Nov;22(22):7916-7919

Department of Anesthesiology and Intensive Care, Fondazione Policlinico Universitario A. Gemelli - IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.

We performed a systematic review of the literature starting from a real case of venous air embolism (VAE) in a young infant undergoing central catheterization during procedural sedation. Air embolism due to internal jugular vein catheterization during procedural sedation is very rare, but it is a potentially life-threatening complication of central catheterization that warrants attention. To our knowledge, this is the first case published in a similar scenario. Read More

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November 2018

Computed tomography pulmonary angiography and venography with a low dose of contrast medium.

Radiol Phys Technol 2018 Dec 10. Epub 2018 Dec 10.

Department of Radiology, Saitama Medical Center, Saitama Medical University, 1981 Kamoda, Kawagoe, Saitama, 350-8550, Japan.

The authors developed a method to ensure sufficient opacification of pulmonary vasculature for separate depiction of arteries and veins in three-dimensional form with a small dose of contrast medium utilizing a test injection to determine optimal timing of computed tomography (CT) scanning. The dose was determined by a simulation based on a pharmacokinetic model. The contrast medium was administered at a rate of 5. Read More

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December 2018

Identification of Two Mutations in PCDHGA4 and SLFN14 Genes in an Atrial Septal Defect Family.

Curr Med Sci 2018 Dec 7;38(6):989-996. Epub 2018 Dec 7.

Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.

Atrial septal defect (ASD) is a common acyanotic congenital cardiac disorder associated with genetic mutations. The objective of this study was to identify the genetic factors in a Chinese family with ASD patients by a whole exome sequencing approach. Causative ASD gene mutations were examined in 16 members from a three-generation family, among which 6 individuals were diagnosed as having ASD. Read More

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December 2018

Evaluation of Antibiotic Treatment on the Duration of Hospitalization of Patients with Erysipelas and Bacterial Cellulitis.

Dermatol Ther (Heidelb) 2018 Dec 7. Epub 2018 Dec 7.

Department of Dermatology, University of Rzeszow, Rzeszow, Poland.

Introduction: Erysipelas and bacterial cellulitis are two of the most common infectious skin diseases. They are usually caused by the β-hemolytic group of Streptococcus, and less frequently by other bacteria. The objective of the study was to assess the factors affecting the length of stay of patients admitted to hospital with erysipelas or bacterial cellulitis. Read More

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December 2018
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Effects of crystalloids and colloids on microcirculation, central venous oxygen saturation, and central venous-to-arterial carbon dioxide gap in a rabbit model of hemorrhagic shock.

J Anesth 2018 Dec 10. Epub 2018 Dec 10.

Department of Cardiovascular Surgery, Tokyo Women's Medical University, 8-1, Kawadacho Shinjuku-ku, Tokyo, 162-8666, Japan.

Objective: The effects of hydroxyethyl starch (HES) on microcirculation, central venous oxygen saturation (ScvO), and the central venous-to-arterial carbon dioxide gap (dCO) are studied in a rabbit model of hemorrhagic shock for elucidating the advantages and drawbacks of resuscitation with HES compared with crystalloids.

Methods: An ear chamber and sublingual mucosa were used to examine blood vessels by intravital microscopy. Hemorrhagic shock was induced by removing nearly half of the blood volume. Read More

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December 2018

Nuclear Factor-κB is Activated in Filter-Implanted Vena Cava.

Cardiovasc Intervent Radiol 2018 Dec 10. Epub 2018 Dec 10.

Department of Surgery, Navicent Health Physician Group, Mercer University School of Medicine and The Medical Center Navicent Health, 1550 College Street, Macon, GA, 31207, USA.

Background: Implantation of a retrievable vena cava filter (VCF) is an effective method for preventing pulmonary embolism. Retrieval of filters, however, may be difficult due to intimal hyperplasia and inflammation in the cava wall. The transcription factor nuclear factor-kappaB (NF-κB) plays an important role in regulation of numerous genes participating in the inflammatory and proliferative responses of cells. Read More

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December 2018

Quantification of Positron Emission Tomography Data Using Simultaneous Estimation of the Input Function: Validation with Venous Blood and Replication of Clinical Studies.

Mol Imaging Biol 2018 Dec 7. Epub 2018 Dec 7.

Department of Biomedical Engineering, Stony Brook University, Stony Brook, NY, 11794, USA.

Purpose: To determine if one venous blood sample can substitute full arterial sampling in quantitative modeling for multiple positron emission tomography (PET) radiotracers using simultaneous estimation of the input function (SIME).

Procedures: Participants underwent PET imaging with [C]ABP688, [C]CUMI-101, and [C]DASB. Full arterial sampling and additional venous blood draws were performed for quantification with the arterial input function (AIF) and SIME using one arterial or venous (vSIME) sample. Read More

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December 2018

Estimation of the number of feeding arteries of spinal arteriovenous malformations by using three-dimensional digital subtraction angiography.

Eur Spine J 2018 Dec 10. Epub 2018 Dec 10.

Department of Neurosurgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

Purpose: Spinal angiography is the gold standard for evaluation or diagnosis of spinal arteriovenous malformations (AVMs). However, some feeding arteries might be overlooked when multiple feeders exist. This study aimed to retrospectively review cases of spinal intra-dural AVMs, which were identified by three-dimensional digital subtraction angiography (3D-DSA), and attempted to estimate the number of feeding arteries. Read More

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December 2018

Concentrated growth factor exudate enhances the proliferation of human periodontal ligament cells in the presence of TNF‑α.

Mol Med Rep 2018 Dec 3. Epub 2018 Dec 3.

Department of Stomatology, The People's Hospital of Longhua, Shenzhen, Guangdong 518109, P.R. China.

The purpose of this study was to evaluate the effects of concentrated growth factor exudate (CGFe) on human periodontal ligament cells (hPDLCs) stimulated by tumor necrosis factor (TNF)‑α. From the peripheral blood of healthy donors, CGFe was prepared according to the Sacco protocol after 7 days of incubation. The hPDLCs were cultured by a tissue explant method and identified with anti‑vimentin and anti‑cytokeratin antibodies. Read More

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December 2018

Segmentation of the Four-Layered Retinal Vasculature Using High-Resolution Optical Coherence Tomography Angiography Reveals the Microcirculation Unit.

Invest Ophthalmol Vis Sci 2018 Dec;59(15):5847-5853

Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Purpose: To differentiate the four layers of the retinal vessel network in the human macula and examine their morphologic features using high-resolution optical coherence tomography angiography (HR-OCTA).

Methods: Macular areas measuring 464 × 464 pixels of 10 right eyes of 10 healthy subjects without ocular disease were scanned 10 times using a HR-OCTA device. Averaged OCTA images were created. Read More

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December 2018

Anatomical proximity dictates successful ablation from adjacent sites for outflow tract ventricular arrhythmias linked to the coronary venous system.

Europace 2018 Dec 10. Epub 2018 Dec 10.

Cardiac Electrophysiology Section, Cardiovascular Division, Hospital of University of Pennsylvania, 9 Founders Pavilion - Cardiology, 3400 Spruce St. Philadelphia, PA, USA.

Aims: Catheter ablation of outflow tract ventricular arrhythmias (OTVAs) with the earliest activation within the coronary venous system (CVS) can be challenging. When ablation from the CVS is not feasible or ineffective, an approach from anatomically adjacent site(s) can be considered. We report the outcomes of an anatomical approach for OTVAs linked to the CVS. Read More

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December 2018

A Preliminary Clinical Trial Comparing Split Treatments to the Face and Hand With Autologous Fat Grafting and Platelet-Rich Plasma (PRP): A 3D, IRB-Approved Study.

Authors:
Gordon H Sasaki

Aesthet Surg J 2018 Dec 10. Epub 2018 Dec 10.

Department of Plastic Surgery, Loma Linda Medical University, Loma Linda, CA.

Background: Numerous methodologies have been suggested to enhance fat graft survival, but few long-term studies are available.

Objectives: The authors of this institutional review board-approved study investigated the safety and efficacy of utilizing platelet-rich plasma (PRP).

Methods: Each of 10 patients received equal volumes of syringe-harvested, centrifuged fat to opposing midfaces with a lateral submuscular aponeurotic system-plication or no face lift and hands that were combined with equal volumes of either concentrated PRP or normal saline. Read More

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December 2018

[Post-surgical ventriculitis due to extensively resistant Pseudomonas aeruginosa treated with intrathecal colistin. Pediatric case report and literature review].

Rev Chilena Infectol 2018 ;35(3):321-325

Universidad CES, Medellín, Colombia.

Use of Intrathecal colistin has increased in recent years and has become an alternative for the management of infections of the central nervous system caused by multidrug resistant (MDR) bacteria. Evidence of therapeutic success and safety profile is increasing, particularly in MDR Acinetobacter baumanii infections in adults. Conversely, evidence in children is limited. Read More

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January 2018

[Epidemiology and risk factors for prolonged hospital length of stay in children with leukemia and bacteremia. Cohort study].

Rev Chilena Infectol 2018 ;35(3):233-238

Servicio de Infectologia, Hospital de Pediatría Juan P. Garrahan, Argentina.

Introduction: Bacteremia is a frequent complication in children with cancer, which is associated with greater severity, prolonged hospitalization and mortality. Prolonged hospitalization conditions greater morbidity and risk of acquisition of intranosocomial infections.

Aim: To describe risk factors for prolonged hospital length of stay in children with leukemia and bacteremia. Read More

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January 2018

[Suspected vascular ehlers danlos syndrome. Case report].

Rev Med Chil 2018 Aug;146(8):938-942

Departamento de Dermatología, Pontificia Universidad Católica de Chile, Santiago, Chile.

Ehlers Danlos Syndrome comprises a heterogeneous group of genetic disorders of the connective tissue, due to defects in collagen or its modifying enzymes. We report a 21 years old male presenting with translucent skin revealing the subcutaneous venous pattern. He had a thin face, large-appearing eyes, thin lips, thin nose, joint hypermotility and history of hip dysplasia. Read More

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A rare cause of ischemic stroke: cardiac myxoma. Case report and review of literature.

Rom J Morphol Embryol 2018 ;59(3):903-909

Department of Internal Medicine, University of Medicine and Pharmacy of Craiova, Romania;

A 46-year-old female diagnosed several years ago with arterial hypertension and an ischemic stroke with significant recovery was admitted for dyspnea on usual physical activity and fatigue. Physical examination revealed signs of heart failure with crackles on both lung bases, distented jugular veins, accentuated pulmonic valve closure (P2) and tricuspid regurgitation murmur. Echocardiography identified a large tumor in the left atrium, suggestive of atrial myxoma, which caused a severe functional mitral stenosis and produced severe pulmonary hypertension. Read More

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January 2018

The effect of sildenafil on retinal blood velocity in healthy subjects.

Eye Vis (Lond) 2018 5;5:30. Epub 2018 Dec 5.

1Department of Ophthalmology, Edith Wolfson Medical Center, 62 Halochamim St, 58100 Holon, Israel.

Purpose: It has been suggested that Sildenafil may have beneficial therapeutic effects in the treatment of neurodegenerative disorders. The retinal circulation is of significant interest as a marker of cerebral vascular disease since the retinal and cerebral vasculatures share many morphological and physiological properties, yet only the retinal circulation can be directly visualized. Therefore, our aim was to assess the change induced by Sildenafil on retinal blood velocity. Read More

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December 2018

Deep Vein Thrombosis Prophylaxis after Total Hip Arthroplasty in Asian Patients.

Authors:
Jun-Shik Kim

Hip Pelvis 2018 Dec 6;30(4):197-201. Epub 2018 Dec 6.

The Joint Replacement Center, Ewha Womans University Medical Center, Seoul, Korea.

In Western patient populations, the reported incidence of imaging-demonstrated deep vein thrombosis (DVT) after total hip arthroplasty (THA) is as high as 70% without prophylaxis. The reported rates of symptomatic pulmonary embolism (PE) after THA in recent studies range from 0.6% to 1. Read More

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December 2018

Total Nose and Upper Lip Replantation: A Case Report and Literature Review.

Plast Reconstr Surg Glob Open 2018 Oct 3;6(10):e1839. Epub 2018 Oct 3.

Division of Plastic Surgery, University of Alberta, Edmonton, Alberta, Canada.

The nose plays a critical role in olfaction, air filtration and humidification, and facial aesthetics. Most nasal amputations result from animal bites, human bites, and lacerations from glass. Successful replantation yields the best aesthetic and functional outcomes and is preferred compared with multistage nasal reconstruction. Read More

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October 2018

Radical nephrectomy and intracaval thrombectomy for advanced renal cancer with extensive inferior vena cava involvement utilising cardiopulmonary bypass and hypothermic circulatory arrest: Is it worthwhile?

Arab J Urol 2018 Dec 30;16(4):378-385. Epub 2018 Jul 30.

Department of Urology, University Hospital of Wales, Heath Park, Cardiff, UK.

Objective: To report our long-term outcomes of surgical treatment of renal tumours with inferior vena cava (IVC) tumour thrombus above the hepatic veins, utilising cardiopulmonary bypass (CBP) and hypothermic circulatory arrest (HCA), as surgical resection remains the only effective treatment for renal cancers with extensive IVC tumour thrombus.

Patients And Methods: We retrospectively reviewed 48 consecutive patients (median age 58 years) who underwent surgical treatment for non-metastatic renal cancer with IVC tumour thrombus extending above the hepatic veins. Perioperative, histological, disease-free (DFS) and overall survival (OS) data were recorded. Read More

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December 2018

Presence of Sarcopenia and Its Rate of Change Are Independently Associated with Long-term Mortality in Patients with Liver Cirrhosis.

J Korean Med Sci 2018 Dec 31;33(50):e299. Epub 2018 Oct 31.

Department of Radiology, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea.

Background: Sarcopenia is associated with a poor prognosis in patients with liver cirrhosis. However, it is not known whether the rate of skeletal muscle depletion is also associated with a poor prognosis. We investigated the prognostic impact of the rate of skeletal muscle depletion in patients with liver cirrhosis. Read More

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December 2018

Pharmacokinetics of rivaroxaban in children using physiologically based and population pharmacokinetic modelling: an EINSTEIN-Jr phase I study.

Thromb J 2018 4;16:32. Epub 2018 Dec 4.

3Clinical Pharmacometrics, Bayer AG, Leverkusen, Germany.

Background: The EINSTEIN-Jr program will evaluate rivaroxaban for the treatment of venous thromboembolism (VTE) in children, targeting exposures similar to the 20 mg once-daily dose for adults. A physiologically based pharmacokinetic (PBPK) model for pediatric rivaroxaban dosing has been constructed.

Methods: We quantitatively assessed the pharmacokinetics (PK) of a single rivaroxaban dose in children using population pharmacokinetic (PopPK) modelling and assessed the applicability of the PBPK model. Read More

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December 2018

Exploratory evaluation of pharmacodynamics, pharmacokinetics and safety of rivaroxaban in children and adolescents: an EINSTEIN-Jr phase I study.

Thromb J 2018 4;16:31. Epub 2018 Dec 4.

11Clinical Development, Bayer AG, Pharmaceuticals, Wuppertal, Germany.

Background: The EINSTEIN-Jr program will evaluate rivaroxaban for the treatment of venous thromboembolism (VTE) in children, targeting exposures similar to the 20 mg once-daily dose for adults.

Methods: This was a multinational, single-dose, open-label, phase I study to describe the pharmacodynamics (PD), pharmacokinetics (PK) and safety of a single bodyweight-adjusted rivaroxaban dose in children aged 0.5-18 years. Read More

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December 2018

Mondor's Disease after Aesthetic Breast Surgery: A Case Series and Literature Review.

J Cutan Aesthet Surg 2018 Jul-Sep;11(3):132-135

Department of Dermatology and Allergology, Städtisches Klinikum Dresden, Academic Teaching Hospital of the Technical University of Dresden, Dresden, Germany.

Background: Mondor's disease of the subcutaneous veins of the breast is an uncommon disorder. The etiology of Mondor's disease remains unclear. Usually, it is a self-limited disease. Read More

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December 2018
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The Rate of Venous Thromboembolism Before and After Spine Surgery as Determined with Indirect Multidetector CT.

JB JS Open Access 2018 Sep 15;3(3):e0015. Epub 2018 Aug 15.

Department of Orthopaedic Surgery, Jichi Medical University, Shimotsuke, Japan.

Background: This prospective cohort study investigated the rate of venous thromboembolism (VTE) before and after spine surgery as determined with use of indirect multidetector computed tomography (MDCT).

Methods: We performed a prospective study of 105 patients (36 women and 69 men ranging in age from 38 to 88 years) undergoing spine surgery at 2 institutions. Indirect MDCT was performed before and 3 days after surgery. Read More

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September 2018

Contrast-Enhanced Ultrasound to Monitor Early Recurrence of Primary Hepatocellular Carcinoma after Curative Treatment.

Biomed Res Int 2018 7;2018:8910562. Epub 2018 Nov 7.

Department of Hepatobiliary Surgery, Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China.

Objective: To evaluate contrast-enhanced ultrasound (CEUS) for monitoring early intrahepatic recurrence of primary hepatocellular carcinoma (HCC) after curative treatment.

Methods: We prospectively analyzed 97 patients (124 nodules) with primary HCC who underwent hepatic resection or radiofrequency ablation and subsequently experienced intrahepatic recurrence. Patients were assessed with conventional ultrasound and CEUS. Read More

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November 2018

The Comparison of the Effect of Mannitol and N Acetyl Cysteine on Liver Function in Partial Hepatectomy.

Anesth Pain Med 2018 Oct 22;8(5):e79677. Epub 2018 Sep 22.

Department of Surgery, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

The alterations in liver function in patients after major liver resection are complex. Partial hepatectomy surgery is considered as a selective therapeutic approach in many benign and malignant liver tumors, secondary metastases, and liver trauma. According to surgical techniques most often based on vascular control and hepatic venous closure (Pringle maneuver), related complications such as ischemia and decreased venous return during and after surgery can be seen. Read More

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October 2018

A case of huge lymphatic and venous malformations of the mediastinum.

Respir Med Case Rep 2019 22;26:53-55. Epub 2018 Nov 22.

Department of Respiratory Medicine, Iizuka Hospital, 3-83 Yoshiomachi, Iizuka, Fukuoka 820-0018, Japan.

We herein report a case of huge lymphatic and venous malformations of the mediastinum (LVM). A 19-year-old man presented for evaluation of a mediastinal mass. On chest computed tomography, the mass demonstrated contrast enhancement and showed dilated veins draining into the superior and inferior vena cava, with multiple scattered calcifications. Read More

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November 2018

Totally Implantable Venous-Access Device Infection Causing Hematogenous Prosthetic Joint Infection: A Retrospective Case Series.

J Bone Jt Infect 2018 31;3(5):241-244. Epub 2018 Oct 31.

Bone-and-Joint Infections Referral Center, Hôpital Croix Saint-Simon, 125, rue d'Avron 75020 Paris, France.

Prosthetic joint infections (PJIs) can be acquired hematogenously from a distant site or device. Notably, 30%-40% of patients with PJIs have bacteremia. No case reports or series of PJIs acquired from totally implantable venous-access device (TIVAD) infection or colonization have been published. Read More

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October 2018

Solving the Chinese Finger Trap: A Novel Method for Simultaneous Superior and Inferior Vena Cava Filter Removal.

Cureus 2018 Oct 2;10(10):e3400. Epub 2018 Oct 2.

Radiology, University of Florida College of Medicine, Jacksonville, USA.

As many as 130,000 inferior vena cava (IVC) filters are placed annually, with as few as 5,000 retrieved a year for patients who no longer require protection from deep vein thrombosis. Superior vena cava (SVC) filter placement is an even less common occurrence and is usually reserved for special cases. Furthermore, the simultaneous placement of IVC and SVC filters is most rare, whereas simultaneous IVC and SVC filter removal has not been reported in the literature. Read More

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October 2018

You Can Do That? Performing Total Recanalization of Completely Stented Arterial-venous Grafts.

Cureus 2018 Oct 1;10(10):e3396. Epub 2018 Oct 1.

Interventional Radiology, University of Florida College of Medicine, Jacksonville, USA.

Establishing venous access in chronic dialysis patients is conducted by the insertion of polytetrafluoroethylene arterial-venous (AV) grafts. The continual access of these grafts allows for potential failure over extended periods of hemodialysis treatment, as a result of thrombosis and pseudoaneurysm formation. Patency of AV grafts requires interventional management of thrombosis and pseudoaneurysm formation, including thrombectomy and covered stent placement, respectively. Read More

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October 2018

Combination of the tubular retractor and brain spatulas provides an adequate operative field in surgery for deep-seated lesions: Case series and technical note.

Surg Neurol Int 2018 1;9:220. Epub 2018 Nov 1.

Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata, Kita-ku, Okayama 700-8558, Japan.

Background: Surgeries for deep-seated lesions are challenging because making a corridor and observing the interface between lesions and normal brain tissue are difficult. The ViewSite Brain Access System, which is a clear plastic tubular retractor system, is used for resection of deep-seated lesions. However, the tapered shape of this system may result in limitation of the surgical field and cause brain injury to observe the interface between lesions and normal tissue. Read More

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November 2018

"First in Man": Case Report of Selective C-Reactive Protein Apheresis in a Patient with Acute ST Segment Elevation Myocardial Infarction.

Case Rep Cardiol 2018 6;2018:4767105. Epub 2018 Nov 6.

Cardiovascular Center Oberallgäu-Kempten, Kempten, Germany.

C-reactive protein (CRP) may be causative in cardiovascular disease. As yet, no specific CRP inhibitor for human application has been described. A 69-year-old male was referred with ST segment elevation myocardial infarction (STEMI). Read More

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November 2018

Rare Copy Number Variants Identify Novel Genes in Sporadic Total Anomalous Pulmonary Vein Connection.

Front Genet 2018 23;9:559. Epub 2018 Nov 23.

Department of Pediatric Cardiovascular, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Total anomalous pulmonary venous connection (TAPVC) is a rare congenital heart anomaly. Several genes have been associated TAPVC but the mechanisms remain elusive. To search novel CNVs and candidate genes, we screened a cohort of 78 TAPVC cases and 100 healthy controls for rare copy number variants (CNVs) using whole exome sequencing (WES). Read More

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November 2018

Ulvan Activates Chicken Heterophils and Monocytes Through Toll-Like Receptor 2 and Toll-Like Receptor 4.

Front Immunol 2018 23;9:2725. Epub 2018 Nov 23.

Amadeite SAS, Bréhan, France.

Responsiveness to invasive pathogens, clearance via the inflammatory response, and activation of appropriate acquired responses are all coordinated by innate host defenses. Toll-like receptor (TLR) ligands are potent immune-modulators with profound effects on the generation of adaptive immune responses. This property is being exploited in TLR-based vaccines and therapeutic agents in chickens. Read More

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November 2018

Optic nerve sheath diameter-guided extubation plan in obese patients undergoing robotic pelvic surgery in steep Trendelenburg position: A report of three cases.

Indian J Anaesth 2018 Nov;62(11):896-899

Department of Anesthesia and Pain Management, Max Superspeciality Hospital, New Delhi, India.

Robotic pelvic surgery requires steep Trendelenburg positioning with pneumoperitoneum which causes raised thoracic and intracranial pressures. In obese patients, the basal thoracic pressures are high. Increased intrathoracic pressure can decrease the cranial venous flow leading to deficient intracranial absorption of cerebrospinal fluid and a further increase in intracranial pressure. Read More

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November 2018
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[Impacto en el desenlace funcional en pacientes con ictus: experiencia de una unidad de cuidados neurovasculares].

Gac Med Mex 2018 ;154(Supp 2):S56-S60

GECEN Investigators: Humberto Leal-Bailey, Mezli Espinosa-Ortega, Nicolás Escobedo-Zuñiga, Denisse Martínez-Roque y Mario Cristóbal-Niño.

Background And Objective: Neurovascular care units (NCU) have a positive impact on the functional prognosis of stroke patients. The effectiveness of NCUs in Mexico has not been evaluated. Our objective was to determine the impact of an NCU in a third-level academic hospital in northeastern of Mexico. Read More

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January 2018

Selective abdominal venous congestion induces adverse renal and hepatic morphological and functional alterations despite a preserved cardiac function.

Sci Rep 2018 Dec 10;8(1):17757. Epub 2018 Dec 10.

BIOMED - Biomedical Research Institute, Faculty of Medicine and Life Sciences, Hasselt University, Diepenbeek, Belgium.

Venous congestion is an important contributor to worsening renal function in heart failure and the cardiorenal syndrome. In patients, it is difficult to study the effects of isolated venous congestion on organ function. In this study, the consequences of isolated abdominal venous congestion on morphology and function of the kidneys, liver and heart were studied in a rat model. Read More

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December 2018

Evaluation of episcleral venous fluid wave during gonioscopy assisted transluminal trabeculotomy in patients with advanced glaucoma.

Eye (Lond) 2018 Dec 10. Epub 2018 Dec 10.

Gazi University, Faculty of Medicine, Department of Ophthalmology, Ankara, Turkey.

Purpose: To evaluate episcleral venous fluid wave (EVFW) during GATT surgery in patients with advanced stage open angle glaucoma and to investigate its relationship with the severity of glaucoma.

Methods: In all, 34 eyes of 28 open angle glaucoma patients who underwent GATT surgery were included into study. The extent of EVFW was evaluated using surgical records of patients and it was defined as number of clock hours. Read More

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December 2018

[Contemporary data on efficacy of anticoagulant therapy in recanalization of deep veins].

Angiol Sosud Khir 2018 ;24(4):185-190

Department for General Surgery and Urology, Volgograd State Medical University under the RF Ministry of Public Health, Volgograd, Russia.

The article is a literature review containing a detailed description of anticoagulant therapy variants, their efficacy in recanalization of deep veins, as well as patients' compliance to treatment. Russian specialists have demonstrated that the processes of active re-organization of thrombotic masses, in some cases leading to complete clearing of the vessel's lumen from a thrombus, may be observed at terms from 3 to 6 months, with a failure to occur within the above period reportedly followed by formation of irreversible cicatricial-sclerotic alterations in the veins. That is why adequate anticoagulant therapy should be initiated promptly in order to prevent the development of irreversible alterations and a decompensated form of chronic venous insufficiency. Read More

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January 2018

[Surgical treatment of patients with superior vena cava syndrome associated with permanent vascular access].

Angiol Sosud Khir 2018 ;24(4):96-100

Republican Clinical Hospital, Kazan, Russia.

Presented herein are two clinical case reports concerning surgical treatment for superior vena cava syndrome in patients suffering from end-stage renal disease and undergoing programmed haemodialysis. Initially attempted roentgen-endovascular recanalization turned out to be unsuccessful. The patients were then subjected to ipsilateral extrathoracic bypass grafting, which made it possible to preserve the vascular access for programmed haemodialysis and to relieve venous hypertension of the limb and the brain, as well as to improve quality of life. Read More

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January 2018

[State of the venous outflow from the small pelvis after surgical correction of pelvioperineal reflux].

Angiol Sosud Khir 2018 ;24(4):90-94

Chair of Faculty Surgery #1, Therapeutic Department, Pirogov Russian National Research Medical University (RNRMU), Moscow, Russia.

Objective: The study was aimed at assessing the venous outflow from the small pelvis after surgical correction of pelvioperineal reflux with the use of reference methods of examination.

Patients And Methods: We examines a total of 43 female patients (aged 41.5±5. Read More

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January 2018

[Damage to subcutaneous nerves in endovenous laser coagulation of the great saphenous vein].

Angiol Sosud Khir 2018 ;24(4):81-87

Department of Surgery, Institute of Additional Professional Education, South Ural State Medical University of the RF Ministry of Public Health, Chelyabinsk, Russia.

The purpose of this study was to assess the incidence of the development of symptoms of damage to subcutaneous nerves after endovenous laser coagulation (EVLC) of the great saphenous vein (GSV), as well as to determine the effect of these symptoms on quality of life (QoL) of patients. Our retrospective study enrolled a total of 119 patients (mean age 50±13.9 years) subjected to 151 isolated EVLC of the GSV. Read More

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January 2018
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[Endotheliotropic effects of venotonic drugs in treatment of patients with varicose veins].

Angiol Sosud Khir 2018 ;24(4):72-74

Department of Cardiovascular, Roentgenoendovascular, Operative Surgery and Topographic Anatomy, Ryazan State Medical University named after Academician I.P. Pavlov under the RF Ministry of Public Health, Ryazan, Russia.

The authors analysed the effect of Venarus on the endothelial function in patients suffering from lower limb varicose veins. Our open-label prospective study included a total of 100 patients diagnosed as having CEAP class C1-C2 varicose veins and divided into two equal groups. Dynamic assessment of the clinical course of the disease in Group One patients was carried out on the background of taking Venarus and compression therapy, with Group Two patients evaluated without taking Venarus. Read More

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January 2018

[Extracorporeal membrane oxygenation in severe combined trauma complicated by fat embolism].

Khirurgiia (Mosk) 2018 (10):76-80

Yudin State Clinical Hospital, Moscow, Russia.

It is presented the victim with severe combined injury complicated by fat embolism and acute respiratory failure. Veno-venous extracorporeal membrane oxygenation was successfully used to provide adequate extracorporeal gas exchange in refractory respiratory failure. Read More

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January 2018

Invasive Hemodynamic Monitoring of Aortic and Pulmonary Artery Hemodynamics in a Large Animal Model of ARDS.

J Vis Exp 2018 Nov 26(141). Epub 2018 Nov 26.

Universitatsklinikum Hamburg-Eppendorf.

One of the leading causes of morbidity and mortality in patients with heart failure is right ventricular (RV) dysfunction, especially if it is due to pulmonary hypertension. For a better understanding and treatment of this disease, precise hemodynamic monitoring of left and right ventricular parameters is important. For this reason, it is essential to establish experimental pig models of cardiac hemodynamics and measurements for research purpose. Read More

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November 2018