15,418 results match your criteria Venous Insufficiency

[The marginal vein-Still a rare entity: case series of 16 patients].

Chirurgie (Heidelb) 2022 Jun 29. Epub 2022 Jun 29.

Gefäßchirurgie, Medizinische Fakultät, Universität Augsburg, Stenglinstr. 2, 86156, Augsburg, Deutschland.

Background: The marginal vein (MV) is a congenital, predominantly venous vascular malformation, which is based on a lack of regression of the embryonic venous system in the lower extremities and is associated with a variety of complications. So far, no uniform treatment regimens have been described in the literature.

Objective: What are the treatment strategies and outcomes in patients with a MV?

Material And Methods: In the period from 1 January 2008 to 31 December 2020, all patients treated at the University Hospital Augsburg with MV were retrospectively reviewed. Read More

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Warfarin resistance: possibilities to solve this problem. A case report.

J Int Med Res 2022 Jun;50(6):3000605221103959

Department of Internal Medicine Number 2, Bogomolets National Medical University, Kyiv, Ukraine.

Effective prevention of thromboembolism is essential for patients with mechanical prosthetic heart valves. For this group of patients, vitamin K antagonists (VKAs) remain the drug group of choice despite the widespread use of new anticoagulants in other diseases. As a consequence, warfarin resistance remains a serious challenge for physicians. Read More

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microRNA-301a-3p is a potential biomarker in venous ulcers vein and gets involved in endothelial cell dysfunction.

Bioengineered 2022 Jun;13(6):14138-14158

Department of Vascular Surgery, Heilongjiang Provincial Hospital, Harbin, Heilongjiang, China.

Venous ulcer is a common contributor to chronic venous insufficiency (CVI) of lower limbs, which seriously affects the life quality of patients. In this study, we researched the expression characteristics of microRNA-301a-3p (miR-301a-3p) in patients with CVI and investigated the impact of miR-301a-3p on the dysfunction of human umbilical vein endothelial cells (HUVECs). The plasma level of miR-301a-3p in normal controls, patients with varicose great saphenous vein, and patients with the venous ulcer of lower limbs were measured. Read More

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[Clinical practice of double lumen cannula for veno-venous extracorporeal membrane oxygenation in adults].

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2022 May;34(5):545-549

Department of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei, China.

Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is a life support technique for patients with severe respiratory failure. In the past, single lumen cannula was mostly used to constract the vascular pathway of extracorporeal membrane oxygenation. Compared with single-lumen cannula, double lumen cannula (DLC) can reduce recirculation fraction, reduce complications such as infection and bleeding, and facilitate patient's rehabilitation. Read More

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Early Results With a New Endovenous Radiofrequency Ablation Catheter, Venclose®.

Vasc Endovascular Surg 2022 Jun 21:15385744221110440. Epub 2022 Jun 21.

Total Vascular Care, Brooklyn, NY, USA.

Objectives: Endovenous Radio-frequency Ablation (RFA) has become a common treatment for chronic venous insufficiency. The Medtronic Closurefast catheter was previously the only RFA catheter approved for use in this procedure. In 2018 VenClose Company's new device was approved. Read More

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A prospective study on hyperhomocysteinemia as an aggravating factor in chronic venous insufficiency.

Exp Ther Med 2022 Jul 17;24(1):449. Epub 2022 May 17.

Clinic of Dermatology, County Emergency Hospital of Sibiu, 550245 Sibiu, Romania.

The role of hyperhomocysteinemia (HH) in the etiopathogenetics of systemic thrombotic events has been confirmed by numerous studies. However, it has been insufficiently studied as an etiopathogenic factor in chronic venous insufficiency (CVI). The present prospective study included 166 patients with CVI at stages C3-C6. Read More

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Chronic Kidney Disease in the Transgender, Nonbinary, or Gender Diverse Person.

Semin Nephrol 2022 Mar;42(2):129-141

Division of Endocrinology and Metabolism, Department of Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada; Division of Endocrinology and Metabolism, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

Nephrologists are increasingly providing care to transgender, nonbinary, and gender diverse (TNBGD) individuals with chronic kidney disease. This narrative review discusses the care of TNBGD individuals from a nephrology perspective. TNBGD individuals are under-represented in the nephrology literature. Read More

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Incompetent perforators do care!

Cees H A Wittens

J Vasc Surg Venous Lymphat Disord 2022 Jul;10(4):965

Emeritus Professor of Venous Surgery, Rotterdam, the Netherlands.

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Fatigue, physical activity and quality of life in people self-reporting symptoms of chronic venous disease.

J Vasc Surg Venous Lymphat Disord 2022 Jun 14. Epub 2022 Jun 14.

Université de Lyon, UJM-Saint-Etienne, Laboratoire Interuniversitaire de Biologie de la Motricité, EA 7424, F-42023, Saint-Etienne, France. Electronic address:

Objective: The aim of this study was to quantify fatigue and quality of life (QoL) in people self-reporting chronic venous disease (CVD) symptoms or at risk of CVD within a large cohort representative of the French population. The relationship between self-reported physical activity and both fatigue and QoL was also investigated. We hypothesised that a greater fatigue and impaired QoL would exist in participants self-reporting CVD symptoms, with the impairments being attenuated in those with greater level of physical activity. Read More

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External validation of Villalta score in high-middle income country patients with deep vein thrombosis.

Medicine (Baltimore) 2022 Jun 17;101(24):e29367. Epub 2022 Jun 17.

Division of Vascular and Endovascular Surgery, Universidade Federal de Sao Paulo, Sao Paulo, Brazil.

Abstract: Post-thrombotic syndrome (PTS) is a late complication that does not have a cure yet, with a prevalence estimated between 20 to 75%, associated with previous deep vein thrombosis event. Although the Villalta score (VS) is the gold-standard clinical tool for diagnostic and prognostic evaluation of PTS, there are currently no VS intra-rater agreement established and no validation studies for VS' application into Brazilian Portuguese. We sought to translate and validate VS reliability systematically; and, secondarily, to compare the ultrasound findings with the severity of PTS. Read More

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J Vasc Surg Venous Lymphat Disord 2022 Jun 13. Epub 2022 Jun 13.

Istanbul University-Cerrahpasa, Medical Faculty of Cerrahpasa, Department of Cardiovascular Surgery, Istanbul, Turkey.

Objective: The aim of this study was to evaluate the effect of inspiratory muscle training(IMT) and calf muscle exercise training(ETC) in addition to compression therapy(CT) on quality of life, venous refilling time, disease severity, pain, edema, range of motion, muscle strength and functionality in patients with chronic venous insufficiency (CVI) compared to compression treatment alone.

Methods: Thirty-two participants diagnosed with CVI were randomly divided into three groups. IMT in addition to compression therapy, Group 1, exercise training for the calf muscle in addition to compression therapy, Group 2, and compression therapy alone, Group 3. Read More

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The Negative Prognostic Role of Inflammatory Biomarkers in Patients With Chronic Cerebrospinal Venous Insufficiency.

Neurologist 2022 Jun 10. Epub 2022 Jun 10.

Departments of Neurology.

Background: The pathologic consequences of inflammatory responses in chronic cerebrospinal venous insufficiency (CCSVI) remains poorly understood. Hence, this study was aimed to evaluate the peripheral inflammatory biomarkers in patients with intracranial and extracranial CCSVI pathology. In addition, the relationship between inflammatory cytokine profile and CCSVI prognosis was also evaluated. Read More

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The Common Haplotype GATGACA in Surfactant-Protein B Gene Is Protective for Respiratory Distress Syndrome in Preterm Neonates.

Front Pediatr 2022 25;10:851042. Epub 2022 May 25.

Department of Physiology, Jessenius Faculty of Medicine, Comenius University, Martin, Slovakia.

Background: Respiratory distress syndrome (RDS), a disorder of primary surfactant deficiency resulting in pulmonary insufficiency, remains a significant problem for preterm neonates. Associations between genetic variants of surfactant proteins and RDS have been reported, but haplotypes of the surfactant protein B gene () have not been studied. The aim of the study was to prove the hypothesis that certain haplotypes of may be protective or risk factors for RDS. Read More

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A Prediction Model for Peak Expiratory Flow Derived From Venous Blood Biomarkers and Clinical Factors in Amyotrophic Lateral Sclerosis.

Front Public Health 2022 27;10:899027. Epub 2022 May 27.

Department of Neurology, West China Hospital, Sichuan University, Chengdu, China.

Although peripheral venous blood biomarkers are related to respiratory function in Amyotrophic lateral sclerosis (ALS) patients, there are still few prediction models that predict pulmonary function. This study aimed to investigate the venous blood biomarkers associated with respiratory function in patients with ALS from southwest China and to create prediction models based on those clinical biomarkers using logistic regression. A total of 319 patients with ALS from the retrospective cohort and 97 patients with ALS from the prospective cohort were enrolled in this study. Read More

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Chronic venous insufficiency: a comprehensive review of management.

J Wound Care 2022 Jun;31(6):510-519

Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, US.

Chronic venous insufficiency is an extensive progressive disease in need of public health attention. This insidious disease is a growing burden on patient quality of life and the health economy. Chronic venous insufficiency has become more pronounced in global populations, especially in regions exhibiting a higher rate of risk factors. Read More

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Computational Analysis of the Related Factors of Deep Vein Thrombosis (DVT) Formation in Patients Undergoing Hip Fracture Surgery.

Evid Based Complement Alternat Med 2022 27;2022:1127095. Epub 2022 May 27.

Department of Orthopedics (Department of Osteoarticular and Sports Medicine), Hunan Provincial People's Hospital (The First-Affiliated Hospital of Hunan Normal University), Changsha 410005, China.

A retrospective study was conducted on 51 patients undergoing hip fracture surgery to investigate the factors associated with the formation of deep venous thrombosis (DVT). The independent sample -test and correlation analysis were used to sort out and analyze the data. The findings are as follows. Read More

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Preeclampsia subtypes: Clinical aspects regarding pathogenesis, signs, and management with special attention to diuretic administration.

Eur J Obstet Gynecol Reprod Biol 2022 Jul 31;274:175-181. Epub 2022 May 31.

National Laboratory for Human Reproduction, University of Pécs, Pécs, Hungary; Department of Obstetrics and Gynaecology, Medical School, University of Pécs, Pécs, Hungary; Doctoral School of Health Sciences, Faculty of Health Sciences, University of Pécs, Pécs, Hungary; Hungarian Academy of Sciences - University of Pécs Human Reproduction Scientific Research Group, University of Pécs, Pécs, Hungary.

During normal pregnancy, blood volume increases by nearly two liters. Distinctively, the absence coupled with the extreme extent regarding the volume expansion, are likely accompanied with pathological conditions. Undoubtedly, preeclampsia, defined as the appearance of hypertension and organ deficiency, such as proteinuria during the second half of pregnancy, is not a homogenous disease. Read More

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[Truncal mechanochemical versus thermal endovenous ablation for varicose vein disease: a systematic review and meta-analysis].

Khirurgiia (Mosk) 2022 (6):116-126

Belarussian State Medical University, Minsk, Republic of Belarus.

Objective: To compare the outcomes of thermal and mechanochemical endovenous ablative techniques in patients with varicose veins.

Material And Methods: We searched the PubMed, EMBASE and Cochrane Library databases for studies devoted to mechanochemical and thermal endovenous ablative techniques from inception until July 2021. The primary outcome was anatomical success. Read More

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[Medical compression stockings for chronic venous diseases and lymphedema : Scientific evidence and results of a patient survey on quality of care].

Hautarzt 2022 Jun 1. Epub 2022 Jun 1.

Praxis für Phlebologie & Dermatologie, Bonn, Deutschland.

Background And Aims: Medical compression stockings (MCS) are indicated for chronic venous insufficiency (CVI) of all stages and are an indispensable component in lymphedema therapy. In all, 8% of the German population has been prescribed MCS by a physician-more women than men (12% vs. 5%), and especially persons aged 60 years and older (17%). Read More

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In vivo investigation of ruminant placenta function and physiology-a review.

J Anim Sci 2022 Jun;100(6)

Department of Biomedical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.

The placenta facilitates the transport of nutrients to the fetus, removal of waste products from the fetus, immune protection of the fetus and functions as an endocrine organ, thereby determining the environment for fetal growth and development. Additionally, the placenta is a highly metabolic organ in itself, utilizing a majority of the oxygen and glucose derived from maternal circulation. Consequently, optimal placental function is required for the offspring to reach its genetic potential in utero. Read More

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Prevalence of chronic venous disease in health staff and its impact on quality of life at 6 months.

Cir Cir 2022 ;90(3):332-337

Departamento de Radiología, Hospital General de Zona N.° 83. Instituto Mexicano del Seugro Social, Morelia, Mich., México.

Objective: To determine the frequency and stages of chronic venous disease (CVD) in health staff and its impact on the quality of life.

Method: Cross-sectional study on health workers, between the ages of 20 and 60, indistinct gender, to remain standing position ≥6.5 hours per day for at least 5 days a week. Read More

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Correlation between cutaneous manifestations and functional alterations in chronic venous disease of the lower extremities.

Actas Dermosifiliogr 2022 May 27. Epub 2022 May 27.

Department of Vascular Medicine, Hospital Privado, Córdoba, Argentina.

Background And Aims: Few studies have evaluated the correlation between the severity of cutaneous manifestations of chronic venous disease (CVD) of the lower limbs measured by the Clinical, Etiologic, Anatomic and Pathophysiologic classification (CEAP) and the Venous Clinical Severity Score (VCSS) combined, its risk factors, and venous reflux determined by Doppler ultrasonography. The purpose of this study was to compare the clinical severity assessed by CEAP and VCSS with known risk factors for CVD and the severity of venous reflux.

Methods: A prospective study was carried out on 250 patients with CVD characterized as C2 to C6 according to the CEAP classification, who attended the departments of Dermatology and Vascular Medicine at the Hospital Privado Universitario de Córdoba from April 2013 to December 2014. Read More

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[Endovascular Therapy of Chronic Iliofemoral Venous Outflow Obstructions].

Dtsch Med Wochenschr 2022 Jun 30;147(11):650-656. Epub 2022 May 30.

Angiology Clinic, Klinikum Hochsauerland GmbH Karolinen Hospital, Arnsberg, Deutschland.

Deep vein thrombosis (DVT) is associated with a high cost burden for health care systems because of secondary cost intensive complications like pulmonary embolism and especially the post thrombotic syndrome (PTS). Current standard therapy of anticoagulation for DVT therapy has not changed through the years leaving patients especially with iliofemoral vein thrombus on a high-risk situation for developing PTS. For patients with chronic venous outflow obstruction of the iliac vein system dedicated venous stents and recanalization techniques are today available. Read More

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Surgical Outcomes of Total Anomalous Pulmonary Venous Connection Repair.

Medicina (Kaunas) 2022 May 23;58(5). Epub 2022 May 23.

Department of Cardiothoracic Surgery, The Children's Memorial Health Institute, 04-736 Warsaw, Poland.

Over the years, surgical repair of total anomalous pulmonary venous connection (TAPVC) outcomes have improved, however, morbidity and mortality still remain significant. This study aims to assess the early and long-term outcomes of surgical treatment of TAPVC children, operated on between 2006 and 2016, in one pediatric center in Poland. : Diagnostics, surgical treatment, and follow-up data from 83 patients were collected. Read More

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Neutrophils Mediate Pulmonary Artery Thrombosis In Situ.

Int J Mol Sci 2022 May 23;23(10). Epub 2022 May 23.

Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK.

Pulmonary embolism is a life-threatening condition, which can result in respiratory insufficiency and death. Blood clots occluding branches of the pulmonary artery (PA) are traditionally considered to originate from thrombi in deep veins (usually in legs). However, growing evidence suggests that occlusion of the vessels in the lungs can develop without preceding deep vein thrombosis (DVT). Read More

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Safety and efficacy of acellular human amniotic fluid and membrane in the treatment of non-healing wounds in a patient with chronic venous insufficiency.

SAGE Open Med Case Rep 2022 21;10:2050313X221100882. Epub 2022 May 21.

Department of Surgery, Transplant Division, The University of Texas Medical Branch, Galveston, TX, USA.

Chronic, non-healing venous ulcers of the lower extremity are often limb-threatening conditions. Their management is characterized by a prolonged and frequently frustrating clinical course that represents an economic burden to both the patient and healthcare system. During the last two decades, thermal ablation of underlying incompetent venous systems has been extensively utilized to treat chronic venous insufficiency. Read More

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Survival and predictors of mortality among chronic kidney disease patients on hemodialysis in Amhara region, Ethiopia, 2021.

BMC Nephrol 2022 May 23;23(1):193. Epub 2022 May 23.

Department of Nursing, School of Nursing and Midwifery, College of Medicine and Health Science, Debre Berhan University, PO box 445, Debre Berhan, Ethiopia.

Background: Despite the high economic and mortality burden of chronic kidney disease, studies on survival and predictors of mortality among patients on hemodialysis in Ethiopia especially in the Amhara region are scarce considering their importance to identify some modifiable risk factors for early mortality to improve the patient's prognosis. So, this study was done to fill the identified gaps. The study aimed to assess survival and predictors of mortality among end-stage renal disease patients on hemodialysis in Amhara regional state, Ethiopia, 2020/2021. Read More

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Randomized prospective comparative study of platelet-rich plasma versus conventional compression in treatment of post-phlebitic venous ulcer.

Vascular 2022 May 22:17085381221104629. Epub 2022 May 22.

Department of Vascular Surgery, Faculty of Medicine, 68780Mansoura University, Mansoura, Egypt.

Objectives: to assess the safety and efficacy of platelet-rich plasma (PRP) as adjunctive to compression therapy for post-phlebitic venous ulcers.

Methods: This is a single-center randomized controlled trial on patients with persistent chronic post-phlebitic lower limb venous ulcers from March 2019 to March 2020. Patients were randomly allocated to one of two equal cohort groups. Read More

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Rationale and current evidence of aquatic exercise therapy in venous disease: A narrative review.

Vascular 2022 May 19:17085381221102783. Epub 2022 May 19.

Anatomy Department, 9311Sapienza University of Rome, Rome, Italy.

Chronic venous disorders (CVD) of the lower limbs can be treated with different strategies. Typically, conservative management is based on compression therapy, anticoagulants and venoactive drugs. Endovenous treatments remain the gold standard to treat saphenous insufficiency, with sclerotherapy and surgery maintaining a role in selected cases. Read More

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Enhanced External Counterpulsation Effects on Venous Leg Symptoms.

Anatol J Cardiol 2022 05;26(5):401-406

Department of Cardiology, Derindere Hospital, İstanbul, Turkey.

Background: Venous diseases encompass a large spectrum of abnormalities in the venous system with complaints, such as aching and swelling. Enhanced external counterpulsa-tion, proven safe and effective in patients with coronary artery disease and chronic heart failure, is a technique that increases venous return and augments diastolic blood pres-sure. This study assessed the effects of enhanced external counterpulsation on symp-toms of venous disease using the Venous Insufficiency Epidemiological and Economic Study-Quality of Life/Symptoms questionnaire. Read More

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