14,807 results match your criteria Venous Insufficiency


[Efficacy of combination of needle extract, hesperidin and vitamin C in treatment of chronic venous diseases].

Angiol Sosud Khir 2021 ;27(2):82-91

Laboratory of Physiology of Visceral Systems named after K.M. Bykov, Institute of Experimental Medicine, Saint Petersburg, Russia.

Background: In Russia, physicians are virtually unaware of drugs based on needle extract. However, abroad, saponins and, in particular, a combined preparation containing needle extract, hesperidin and vitamin C is one of drugs of choice, if not the leading medication in treatment of venous oedemas and other venous symptoms.

Aim: The authors conducted a systematic review of the Russian-and English-language literature using the following search terms: saponins, hesperidin, needle, ruscus, ruscogenin (and their Russian equivalents), each of which was entered in a combination with the word 'venous' or its Russian equivalent, respectively. Read More

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January 2021

[Connection of perforating and intramuscular veins of the crus in varicosity].

Angiol Sosud Khir 2021 ;27(2):73-81

Educational and Methodological Division, Institute of Human Brain named after N.P Bekhtereva, Russian Academy of Sciences, Saint Petersburg, Russia.

Aim: This study was undertaken to investigate the clinical anatomy of indirect perforating veins and their connection to the intramuscular venous collector of the crus by means of MSCT phlebography.

Patients And Methods: From 2015 till now, MSCT phlebography was used to examine a total of 400 patients with chronic diseases of lower limb veins. According to the CEAP classification, clinical class C0-C1 was present in 108 (27%) subjects, C2-C3 - in 173 (43. Read More

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January 2021

Chronic venous insufficiency and graduated compression stockings: analysis of public health system patients' adherence to treatment.

J Vasc Bras 2021 Jun 4;20:e20200034. Epub 2021 Jun 4.

Pontifícia Universidade Católica do Paraná - PUCPR, Curitiba, PR, Brasil.

Background: Chronic venous insufficiency (CVI) is a pathology of great importance due to its high worldwide prevalence, affecting up to 80% of the population. Its incidence increases with age and is more frequent in females. One of the most important treatment options is compression therapy and the main method employed is wearing graduated compression stockings, which is considered the basic treatment for CVI regardless of the patient's clinical classification. Read More

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Diving-related disorders in commercial breath-hold divers (Ama) of Japan.

Diving Hyperb Med 2021 Jun;51(2):199-206

Department of Environmental Medicine, Kurume University School of Medicine, Kurume, Japan.

Decompression illness (DCI) is well known in compressed-air diving but has been considered anecdotal in breath-hold divers. Nonetheless, reported cases and field studies of the Japanese Ama, commercial or professional breath-hold divers, support DCI as a clinical entity. Clinical characteristics of DCI in Ama divers mainly suggest neurological involvement, especially stroke-like cerebral events with sparing of the spinal cord. Read More

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Early Results of Popliteal Vein External Banding for Treatment of Chronic Venous Insufficiency.

Ann Vasc Surg 2021 Jun 18. Epub 2021 Jun 18.

Emory University Hospital, Department of Surgery, Division of Vascular Surgery, 1364 Clifton Rd, NE, Atlanta, GA, USA, 30322; Grady Health, Department of Surgery, Division of Vascular Surgery, 80 Jesse Hill Jr Dr SE, Atlanta, GA, USA, 30303. Electronic address:

Introduction: Chronic venous insufficiency (CVI) encompasses a myriad of clinical manifestations including lower extremity swelling and pain, ulcerations and chronic skin changes such as stasis dermatitis, and lipodermatosclerosis. CVI effects greater than 25 million Americans and has a significant socioeconomic and psychosocial impact. Treatment of CVI varies depending on the etiology. Read More

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Registry to investigate the efficacy and safety of the VenaBlock VeIn SEaling system for VaRicose veins in SingApore - Six months results of the RIVIERA trial.

Phlebology 2021 Jun 21:2683555211025181. Epub 2021 Jun 21.

Department of Vascular Surgery, Singapore General Hospital, Singapore, Singapore.

Background: The Venablock Venous Closure System (Invamed, Ankara, Turkey) is a novel cyanoacrylate-based non-thermal non-tumescent embolization device to block refluxing truncal veins for chronic venous insufficiency and varicose veins. The aim was to prospectively evaluate the safety and 6 months efficacy of Venablock for the treatment of primary great saphenous vein (GSV) and small saphenous vein (SSV) incompetency in a multi-ethnic cohort from Singapore.

Methods: This was a single arm, single investigator prospective study of 29 patients (39 limbs, 39 truncal veins) recruited over a 5-month period (August 2019 to February 2020), who were treated with the Venablock device at a tertiary vascular unit in Singapore. Read More

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Single-stage treatment with iliac vein stenting and stripping of great saphenous veins for patients with left iliac vein compression syndrome.

Asian J Surg 2021 Jun 17. Epub 2021 Jun 17.

Department of Vascular Surgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, 310009, China.

Background: We sought to evaluate the safety and feasibility of single-stage treatment with left iliac vein stenting and saphenous stripping in patients with left iliac vein compression (LIVC) and left great saphenous vein (GSV) incompetence.

Method: s: We conducted a prospective cohort study of 72 patients diagnosed with LIVC and left GSV incompetence between June 2012 to Oct 2018. We evaluated the periprocedural, 30-day, and 1-year outcomes of venous clinical severity score (VCSS), Chronic Venous Insufficiency Questionnaire 2 (CIVIQ2), the success rate of stent placement, duration of intervention, length of hospital stay, duplex recurrence, and clinically visible recurrence. Read More

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Tissue remodelling and increased DNA damage in patients with incompetent valves in chronic venous insufficiency.

J Cell Mol Med 2021 Jun 20. Epub 2021 Jun 20.

Ramón y Cajal Institute of Healthcare Research (IRYCIS), Madrid, Spain.

Chronic venous insufficiency (CVI), in which blood return to the heart is impaired, is a prevalent condition worldwide. Valve incompetence is a complication of CVI that results in blood reflux, thereby aggravating venous hypertension. While CVI has a complex course and is known to produce alterations in the vein wall, the underlying pathological mechanisms remain unclear. Read More

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Ovarian Vein Embolization: How and When Should It Be Done?

Tech Vasc Interv Radiol 2021 Mar 16;24(1):100732. Epub 2021 Apr 16.

Associate Professor of Radiology, Section of Interventional Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL. Electronic address:

Pelvic Venous Disease (PeVD) is characterized by pelvic varicosities and chronic pelvic pain, defined as noncyclic pelvic pain that persists for more than 6 months. Pain and discomfort related to PeVD typically worsen with upright positioning and occur more frequently in multiparous and premenopausal women. The most common cause of PeVD is pelvic venous insufficiency (PVI) due to incompetent valves. Read More

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Ultrasound-guided foam sclerotherapy is safe and effective in the management of superficial venous insufficiency of the lower extremity.

J Vasc Surg Venous Lymphat Disord 2021 Jul;9(4):1031-1040

Division of Mohs Surgery, Dermatology & Vascular Surgery, Scripps Clinic, San Diego, Calif.

Background: Superficial venous disease of the lower extremity has a significant impact on quality of life. Both truncal and tributary vein reflux contribute to this disease process. Endovenous foam sclerotherapy is a widely used technique throughout the world for the management of superficial venous reflux and ultrasound guidance improves its safety and efficacy. Read More

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Ultrasonographic hemodynamical and epidemiological factors in advancement of clinical manifestations in primary varicose veins.

Int Angiol 2021 Jun 18. Epub 2021 Jun 18.

Division of Vascular Surgery, Second Department of Surgery, Faculty of Health Sciences, School of Medicine, G. Gennimatas Teaching Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Background: Primary varicose veins (PVV) represent the most prominent clinical manifestation of chronic venous disease (CVD) and has a complex pathophysiological background. Objective of our study was to investigate the impact of sonographic hemodynamical and contemporary epidemiological factors on the clinical severity of PVV.

Methods: We analyzed the sonographic hemodynamical and clinical parameters from 159 consecutive CVD patients and 233 lower limbs with PVV of clinical stages C2, C3 and C4. Read More

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The relationship between clinical severity and outcome measures in patients with chronic venous insufficiency with or without leg ulcer.

J Tissue Viability 2021 Jun 8. Epub 2021 Jun 8.

Department of Cardiovascular Surgery, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.

Purpose: To evaluate the relationship between clinical severity and functionality, sleep quality, depression, and quality of life (QoL) in patients with CVI with or without leg ulcers.

Methods: A total of sixty patients with CVI were enrolled in the study. The patients were C2-6 according to the CEAP classification. Read More

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Impact of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers on Renal Function in Type 1 Cardiorenal Syndrome.

J Cardiovasc Pharmacol Ther 2021 Jun 17:10742484211022625. Epub 2021 Jun 17.

Department of Pharmacy Services, 25213SSM Health Saint Louis University Hospital, St. Louis, MO, USA.

Introduction: Angiotensin-converting enzyme inhibitor (ACE-I) and angiotensin receptor blocker (ARB) discontinuation during acute heart failure (AHF) is associated with increased mortality following hospitalization. Although the etiology of acute kidney injury (AKI) in type 1 cardiorenal syndrome (CRS) has been linked to renal venous congestion, ACE-I/ARB withdrawal (AW) theoretically promotes renal function recovery. ACE-I/ARBs are dose-reduced or withheld in approximately half of patients with CRS, but the subsequent impact on renal function remains largely uninvestigated. Read More

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Extracorporeal Oxygenation Techniques in Adult Critical Airway Obstruction: A Review.

Prague Med Rep 2021 ;122(2):61-72

Departments of General Anesthesiology and Outcomes Research, Cleveland Clinic, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, USA.

Extracorporeal life support has been increasingly utilized in different clinical settings to manage either critical respiratory or heart failure. Complex airway surgery with significant or even total perioperative airway obstruction represents an indication for this technique to prevent/overcome a critical period of severe hypoxaemia, hypoventilation, and/or apnea. This review summarizes the current published scientific evidence on the utility of extracorporeal respiratory support in airway obstruction associated with hypoxaemia, describes the available methods, their clinical indications, and possible limitations. Read More

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Jejunoileal Atresia: A National Cohort Study.

Front Pediatr 2021 31;9:665022. Epub 2021 May 31.

Department of Pediatric Surgery and Pediatric Urology, University Hospital, Goethe University Frankfurt, Frankfurt am Main, Germany.

Jejunoileal atresia (JIA) is a rare disease. We aimed to determine the overall incidence of this malformation and associated malformations in a national cohort. Furthermore, we compared the treatment results of this cohort with the current literature. Read More

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Clinical validation of a machine-learning-based handheld 3-dimensional infrared wound imaging device in venous leg ulcers.

Int Wound J 2021 Jun 14. Epub 2021 Jun 14.

Vascular Surgery Service, Department of General Surgery, Tan Tock Seng Hospital, Singapore, Singapore.

Chronic venous insufficiency is a chronic disease of the venous system with a prevalence of 25% to 40% in females and 10% to 20% in males. Venous leg ulcers (VLUs) result from venous insufficiency. VLUs have a prevalence of 0. Read More

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Respiratory Failure in Noonan Syndrome Treated by Microsurgical Thoracic Duct-Venous Anastomosis.

Ann Thorac Surg 2021 Jun 8. Epub 2021 Jun 8.

Division of Plastic Surgery, Department of Surgery, University of Pennsylvania. Electronic address:

Noonan Syndrome is a disorder characterized by central and peripheral lymphatic conducting anomalies, leading to chylothorax, chylous ascites, and metabolic derangement. Novel imaging modalities including dynamic contrast magnetic resonance lymphangiography (DCMRL) and intranodal lymphangiography have allowed for increased visualization of lymphatic pathology. We describe the first study of a 61-year-old male with Noonan syndrome who developed severe pulmonary insufficiency and chylothoraces. Read More

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Relationship Between Vitamin D Status and the Relevant Parameters of Glucose in Patients with Type 2 Diabetes.

Diabetes Metab Syndr Obes 2021 3;14:2489-2494. Epub 2021 Jun 3.

Department of Internal Medicine, Hue University of Medicine and Pharmacy, Hue City, Vietnam.

Introduction: Clarifying the prevalence of vitamin D deficiency in diabetic patients, and the relationship between vitamin D concentration and insulin resistance, fasting plasma glucose, and HbA1C in patients in Hue City, Vietnam.

Methods: A cross-sectional study on 110 diabetic patients examined at Hue Central Hospital and Hue University of Medicine and Pharmacy Hospital. These patients were collected venous blood sampling, and the 25(OH)D test, fasting plasma glucose test, fasting insulin test, HOMA-IR and QUICKI calculation. Read More

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The Need for Perforator Treatment After VenaSeal and ClosureFast Endovenous Saphenous Vein Closure in CEAP 6 Patients.

J Vasc Surg Venous Lymphat Disord 2021 Jun 7. Epub 2021 Jun 7.

University of California San Francisco-Fresno, Fresno, CA.

Objectives: The authors have previously demonstrated that VenaSeal (Medtronic, Inc., Minneapolis, MN) adhesive, compared to radiofrequency ablation (RFA, ClosureFast, Medtronic, Inc., Minneapolis, MN), in treatment of refluxing saphenous veins in CEAP 6 limbs, results in shorter healing times of venous ulcers. Read More

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Epidemiology and Genetics of Venous Thromboembolism and Chronic Venous Disease.

Circ Res 2021 Jun 10;128(12):1988-2002. Epub 2021 Jun 10.

Department of Surgery, Division of Vascular Surgery, Stanford University School of Medicine, CA (R.A.B., E.F.).

Venous disease is a term that broadly covers both venous thromboembolic disease and chronic venous disease. The basic pathophysiology of venous thromboembolism and chronic venous disease differ as venous thromboembolism results from an imbalance of hemostasis and thrombosis while chronic venous disease occurs in the setting of tissue damage because of prolonged venous hypertension. Both diseases are common and account for significant mortality and morbidity, respectively, and collectively make up a large health care burden. Read More

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Management of Patients when Superficial Venous Disease Arises from Pelvic Escape Points.

Semin Intervent Radiol 2021 Jun 3;38(2):226-232. Epub 2021 Jun 3.

Department of Clinical Radiology and Surgery, Hospital of the University of Pennsylvania - Perelman School of Medicine, Philadelphia, Pennsylvania.

Chronic pelvic pain (CPP) is a common condition in women that carries with it significant morbidity. It is commonly seen in patients presenting to obstetrics and gynecology outpatient clinic visits. CPP is a presenting symptom of various pathologies including pelvic varicocele, pelvic adhesions, spastic colon syndrome, uterine fibroids, endometriosis, and psychosomatic disorders. Read More

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Choosing the Best Treatment Approach for Axial Vein Reflux: Thermal versus Nonthermal Approaches.

Semin Intervent Radiol 2021 Jun 3;38(2):209-214. Epub 2021 Jun 3.

Northwestern University, Feinberg School of Medicine, Chicago, Illinois.

Chronic venous insufficiency is a common and treatable medical condition which has a high morbidity if left untreated, progressing to lower extremity edema, skin changes of lipodermatosclerosis, and venous ulceration. Treatment options have significantly expanded over the last several decades, shifting away from the traditional surgical approach to more minimally invasive procedures such as endoluminal venous laser ablation or radiofrequency ablation. Even more recently, several techniques using nonthermal methods to ablate varicose veins have been developed, which offer the advantage of not requiring labor-intensive and painful tumescent anesthesia to protect the surrounding tissues. Read More

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Updates in Magnetic Resonance Venous Imaging.

Semin Intervent Radiol 2021 Jun 3;38(2):202-208. Epub 2021 Jun 3.

Department of Radiology, NorthShore University HealthSystem, Chicago, Illinois.

For years, magnetic resonance angiography (MRA) has been a leading imaging modality in the assessment of venous disease involving the pelvis and lower extremities. Current advancement in noncontrast MRA techniques enables imaging of a larger subset of patients previously excluded due to allergy or renal insufficiency, allowing for preintervention assessment and planning. In this article, the current status of MR venography, with a focus on current advancements, will be presented. Read More

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Wound Care for Venous Ulceration.

Semin Intervent Radiol 2021 Jun 3;38(2):194-201. Epub 2021 Jun 3.

Harvard Medical School, Department of Radiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts.

Venous leg ulcers (VLUs) affect as many as 20% of patients with advanced chronic venous insufficiency and are associated with significant morbidity and health care costs. VLUs are the most common cause of leg ulcers; however, other etiologies of lower extremity ulcerations should be investigated, most notably arterial insufficiency, to ensure appropriate therapy. Careful clinical examination, standardized documentation, and ultrasound evaluation are needed for diagnosis and treatment success. Read More

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Evaluation and Management of Patients with Leg Swelling: Therapeutic Options for Venous Disease and Lymphedema.

Semin Intervent Radiol 2021 Jun 3;38(2):189-193. Epub 2021 Jun 3.

Division of Interventional Radiology, Department of Radiology, Weill Cornell Medical College, New York, New York.

Lower extremity swelling is a common condition which has a variety of etiologies and can be challenging to diagnose and manage. Swelling is usually the result of the accumulation of interstitial fluid in the subcutaneous tissues. Common etiologies include systemic, superficial, and deep venous, and lymphatic disorders. Read More

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Physical Examination and Ultrasound Evaluation of Patients with Superficial Venous Disease.

Semin Intervent Radiol 2021 Jun 3;38(2):167-175. Epub 2021 Jun 3.

Division of Interventional Radiology, Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California.

Systematic and standardized evaluation of superficial venous disease, guided by knowledge of the various clinical presentations, venous anatomy, and pathophysiology of reflux, is essential for appropriate diagnosis and optimal treatment. Duplex ultrasonography is the standard for delineating venous anatomy, detecting anatomic variants, and identifying the origin of venous insufficiency. This article reviews tools and techniques essential for physical examination and ultrasound assessment of patients with superficial venous disease. Read More

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Treatment of Nonthrombotic Iliac Vein Lesions.

Semin Intervent Radiol 2021 Jun 3;38(2):155-159. Epub 2021 Jun 3.

Division of Interventional Radiology, Department of Radiology, Northwestern University, Chicago, Illinois.

Nonthrombotic iliac vein lesions (NIVLs) most frequently result from extrinsic compression of various segments of the common or external iliac vein. Patients develop symptoms associated with chronic venous insufficiency (CVI); female patients may develop symptoms of pelvic venous disease. Given that iliac vein compression can be clinically silent, a thorough history and physical examination is mandatory to exclude other causes of a patient's symptoms. Read More

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Evaluation of pentoxifylline and ferrous sulfate for treatment of lower limb venous ulcers.

J Vasc Bras 2021 May 24;20:e2020167. Epub 2021 May 24.

Universidade Federal de Pernambuco - UFPE, Recife, PE, Brasil.

Background: Venous ulcers (VU) are the most advanced stage of chronic venous disease (CVD) of the lower limbs. They are frequently associated with episodes of hemorrhage that can provoke chronic anemia (CA), delaying healing. There are no studies in the literature analyzing the prevalence of CA among patients with VU of the lower limbs and few studies have analyzed use of pentoxifylline to treat VU of the lower limbs. Read More

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[MORPHOMETRIC ASSESSMENT OF PECULIARITIES OF BLOOD VESSELS OF THE TESTIS IN EXPERIMENTAL ANIMALS AT ARTERIAL HYPERTENSION IN A LITTLE CIRCLE OF CIRCULATION].

Georgian Med News 2021 Apr(313):163-168

I. Horbachevsky Ternopil National Medical University,Ukraine.

Aim of the research - to study the features of the structural reconstruction of blood vessels of the testes of experimental animals at arterial hypertension in the pulmonary circulation using a complex of morphological methods. Experiments were carried out on 78 laboratory sexually mature white male rats, which were divided into 3 groups. The 1 group included 15 intact practically healthy animals, 2 - 48 rats with hypertension in the pulmonary circulation and compensated cor pulmonale, 15 animals with pulmonary hypertension, which developed decompensation of cor pulmonale, constituted the 3 group. Read More

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Utility of the 50% stenosis criterion for patients undergoing stenting for chronic iliofemoral venous obstruction.

J Vasc Surg Venous Lymphat Disord 2021 Jun 5. Epub 2021 Jun 5.

The RANE Center for Venous and Lymphatic Diseases, St Dominic Hospital, Jackson, Miss.

Objective: The criterion for venous stenting in symptomatic chronic iliofemoral venous obstruction has been the arbitrary use of stenosis of ≥50%. In the present study, we evaluated the intravascular ultrasound (IVUS)-determined degree of stenosis in patients who had undergone stenting for quality of life (QOL)-impairing symptoms and assessed the utility of the 50% stenosis cutoff.

Methods: A retrospective review of contemporaneously entered electronic medical record data from 480 continuous patients (480 limbs) with initial iliofemoral stents placed (2014 to 2017) for symptomatic chronic iliofemoral venous obstruction impairing their QOL was performed. Read More

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