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    [Results of endovascular treatment of obstructive lesions of veins of the iliofemoral segment].
    Angiol Sosud Khir 2018 ;24(2):57-68
    Russian Medical Academy of Continuous Professional Education under the RF Ministry of Public Health, Moscow, Russia.
    Objective: The purpose of the study was to assess the immediate and remote results of endovascular treatment of obstructive lesions of the veins of the iliofemoral segment.

    Patients And Methods: We performed balloon angioplasty and stenting for iliofemoral venous thrombosis in a total of 75 patients. Of these, 60 patients were subjected to stenting of post-thrombotic obstructions and 15 patients underwent stenting of non-thrombotic obstructive lesions of the iliac veins (for May-Thurner syndrome - in 11, for extravasal tumour-induced compression and cicatricial stenosis - in 4). Read More

    Health and economic benefits of advanced pneumatic compression devices in patients with phlebolymphedema.
    J Vasc Surg 2018 Jun 15. Epub 2018 Jun 15.
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Falk Cardiovascular Research Center, Stanford, Calif. Electronic address:
    Objective: Phlebolymphedema (chronic venous insufficiency-related lymphedema) is a common and costly condition. Nevertheless, there is a dearth of evidence comparing phlebolymphedema therapeutic interventions. This study sought to examine the medical resource utilization and phlebolymphedema-related cost associated with Flexitouch (FLX; Tactile Medical, Minneapolis, Minn) advanced pneumatic compression devices (APCDs) relative to conservative therapy (CONS) alone, simple pneumatic compression devices (SPCDs), and other APCDs in a representative U. Read More

    Clinical Characteristics of Thai Chronic Venous Insufficiency (CVI) Patients.
    J Med Assoc Thai 2017 Jan;100(1):17-23
    Objective: To study the demographic and clinical presentations as assessed by Clinical Severity Score (VCSS) and Venous Disability Score (VDS) in Thai Chronic Venous Insufficiency (CVI) patients.

    Material And Method: Retrospective review of prospectively collected data

    Results: There were 78 CVI patients (102 legs) with the mean age of 59.6 years and 42% spending more than 75% of working hours upright. Read More

    Effects of intermittent pneumatic compression treatment on clinical outcomes and biochemical markers in patients at low mobility with lower limb edema.
    J Vasc Surg Venous Lymphat Disord 2018 Jul;6(4):500-510
    Department of Morphology, Surgery and Experimental Medicine, Unit of Translational Surgery, University Hospital of Ferrara, and Vascular Diseases Center, University of Ferrara, Ferrara, Italy.
    Objective: We aimed to evaluate the effects of intermittent pneumatic compression (IPC) in patients at low mobility with leg edema.

    Methods: A pilot, two-arm, randomized controlled clinical trial was performed. Fifty patients (age, 58. Read More

    Retrograde administration of ultrasound-guided endovenous microfoam chemical ablation for the treatment of superficial venous insufficiency.
    J Vasc Surg Venous Lymphat Disord 2018 Jul;6(4):477-484
    Deak Vein NJ Clinic, Somerset, NJ. Electronic address:
    Objective: This study measured patient outcomes among symptomatic patients with superficial chronic venous insufficiency who were treated with retrograde ultrasound-guided polidocanol microfoam 1% in a community setting.

    Methods: Between March 2015 and June 2017, 250 symptomatic patients with C2-C6 chronic venous insufficiency received polidocanol microfoam 1% and were followed for 16 ± 7 months. Sixteen of the 250 patients (6. Read More

    Perioperative Glucocorticoid Treatment of Soft Tissue Reconstruction in Patients on Long-term Steroid Therapy: The Experience of 6 Cases Using Reversed Posterior Interosseous Flap for Hand Neoplasm Surgery.
    Ann Plast Surg 2018 Jun 13. Epub 2018 Jun 13.
    From the Department of Plastic and Reconstruction Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
    Introduction: Long-term steroid therapy is associated with increased postoperative morbidity. Whether to use a stress dose of glucocorticoids (GCs) in surgical patients remains controversial. In the present study, we reported our experience in perioperative GC treatment of 6 patients on long-term steroid therapy for autoimmune diseases undergoing hand reconstruction using reversed interosseous flap. Read More

    Pulmonary venous varix associated with mitral regurgitation mimicking a mediastinal mass: A case report and review of the literature.
    Radiol Case Rep 2018 Apr 8;13(2):404-407. Epub 2018 Feb 8.
    Rashid Hospital, Dubai Health Authority, Oud Metha Street, PO Box 4545, Dubai, United Arab Emirates.
    Pulmonary vein varix is an unusual cause of a mediastinal mass on a chest radiograph. It may be found as an isolated malformation or as a sequela of pulmonary venous hypertension. We encountered a case presenting with left hemiparesis and a past medical history of rheumatic heart disease. Read More

    Treating great and small saphenous vein insufficiency with histoacryl in patients with symptomatic varicose veins and increased risk of surgery.
    Vasa 2018 Jun 12:1-8. Epub 2018 Jun 12.
    1 Department of Cardiology, 2nd Faculty of Medicine, Charles University, Prague and Motol University Hospital, Prague, Czech Republic.
    Background: Treating great and small saphenous vein trunk insufficiency with cyanoacrylate glue is the least taxing treatment method of all available techniques. Due to long-term unavailability of commercial kits with n-butyl-2-cyanoacrylate (histoacryl) in the Czech Republic, we used a modified technique.

    Patients And Methods: Fifty-six limbs in 49 patients suffering from great saphenous vein or small saphenous vein insufficiency in combination with symptomatic chronic venous insufficiency and complicating comorbidities were treated with a modified endovascular cyanoacrylate glue application technique. Read More

    [Short-term clinical safety and efficacy of No-touch great saphenous vein harvesting technique for off-pump coronary artery bypass grafting].
    Zhonghua Yi Xue Za Zhi 2018 May;98(20):1601-1604
    Department of Cardiovascular Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Vessel Disease, Beijing 100029, China.
    To evaluated early clinical outcomes of saphenous vein grafts harvested with a No-touch technique in off-pump coronary artery bypass graft (OPCABG) surgery. A total of 124 patients with three-vessel disease undergoing OPCABG by No-touch technique between June and November 2017 in Beijing An Zhen Hospital were respectively reviewed. The average age of patients was (60. Read More

    Autologous platelet-rich plasma in the treatment of venous leg ulcers in primary care: a randomised controlled, pilot study.
    J Wound Care 2018 Jun;27(Sup6):S20-S24
    Regenerative Medicine Laboratory, BioCruces Health Research Institute, Cruces University Hospital, Spain.
    Objective: To examine the potential efficacy and safety of autologous platelet-rich plasma (PRP) in comparison with the conventional treatment (standard care, SoC) for the treatment of leg ulcers in patients with chronic venous insufficiency, in a primary health-care setting.

    Method: A Phase I-II, open-label, parallel-group, multicentre, randomised pilot study was conducted. The outcome variables at baseline and at weeks five and nine included reduction in the ulcer area, Chronic Venous Insufficiency Quality of Life Questionnaire score, cost of the treatment for up to nine weeks and average weekly cure rate. Read More

    Impact of daytime continuous veno-venous haemofiltration on treatment of paediatric tumour lysis syndrome.
    J Int Med Res 2018 Jan 1:300060518776426. Epub 2018 Jan 1.
    1 Department of Pediatrics, West China Second University Hospital, Sichuan University, Sichuan Province, China.
    Objective Continuous renal replacement therapy (CRRT) is well suited for treating metabolic abnormalities and renal insufficiency associated with tumour lysis syndrome (TLS). However, there is controversy regarding the choice of time for CRRT, the selection of CRRT models, and methods of decreasing complications of CRRT. This study aimed to evaluate the efficacy and outcomes of daytime continuous veno-venous haemofiltration (CVVH) for treating paediatric TLS. Read More

    Radiological identification and analysis of soft tissue musculoskeletal calcifications.
    Insights Imaging 2018 Jun 7. Epub 2018 Jun 7.
    Department of Radiology, Radio-Oncology and Nuclear Medicine, Centre hospitalier de l'Université de Montréal, 1000 rue Saint-Denis, Montréal, QC, H2X 0C1, Canada.
    Musculoskeletal calcifications are frequent on radiographs and sometimes problematic. The goal of this article is to help radiologists to make the correct diagnosis when faced with an extraosseous musculoskeletal calcification. One should first differentiate a calcification from an ossification or a foreign body and then locate the calcification correctly. Read More

    [Elephantiasis of the left lower limb].
    Pan Afr Med J 2018 31;29:95. Epub 2018 Jan 31.
    Service de Dermatologie, Hôpital Militaire d'Instruction Mohamed V, Rabat, Maroc.
    We report the case of a 48-year old female patient with a pathological history of chronic venous insufficiency which required a surgical treatment 5 years before, presenting in the Department of Dermatology with increased left lower limb evolved over the past 4 years. Clinical examination showed increased lower limb, compared to the contralateral limb, with surgical scar at the level of the external face of the left leg and some papillomatous lesions involving the entire left foot and covering the five left toes. The diagnosis of post-traumatic lymphedema (post-surgical) was retained. Read More

    Pathophysiological Mechanisms of Chronic Venous Disease and Implications for Venoactive Drug Therapy.
    Int J Mol Sci 2018 Jun 5;19(6). Epub 2018 Jun 5.
    Departamento de Cirurgia e Fisiologia, Faculdade de Medicina da Universidade do Porto, 4200-319 Porto, Portugal.
    Chronic venous disease (CVD) is a common pathology, with significant physical and psychological impacts for patients and high economic costs for national healthcare systems. Throughout the last decades, several risk factors for this condition have been identified, but only recently, have the roles of inflammation and endothelial dysfunction been properly assessed. Although still incompletely understood, current knowledge of the pathophysiological mechanisms of CVD reveals several potential targets and strategies for therapeutic intervention, some of which are addressable by currently available venoactive drugs. Read More

    Value of Contrast-Enhanced Ultrasound in Detecting Competent and Incompetent Lower-Extremity Perforating Veins.
    Ultrasound Med Biol 2018 May 29. Epub 2018 May 29.
    Department of General Surgery, General Hospital of Tianjin Medical University, Tianjin, China.
    The purpose of this study was to investigate the value of contrast-enhanced ultrasound (CEUS) in the identification of competent and incompetent lower-extremity perforating veins. Patients with chronic venous insufficiency who met the inclusion criteria were enrolled. All patients underwent pre-operative CEUS and color Doppler ultrasound (CDU) and accepted subfascial endoscopic perforator surgery. Read More

    A new risk assessment model for the stratification of the thromboembolism risk in medical patients: the TEVERE score.
    Minerva Med 2018 May 31. Epub 2018 May 31.
    Emergency Department - AUSL UMBRIA1 Assisi, Perugia, Italy -
    Objectives: In hospitalized medical patients, the VTE risk is notable. Nevertheless, the available assessment model (TPF) is generally underused. In this work, we propose an ex novo risk assessment model based on the elaboration of the clinical data exhibited by the TEV patients. Read More

    Escin-induced DNA damage promotes escin-induced apoptosis in human colorectal cancer cells via p62 regulation of the ATM/γH2AX pathway.
    Acta Pharmacol Sin 2018 May 31. Epub 2018 May 31.
    Department of General Surgery, Second Affiliated Hospital of Soochow University, Suzhou 215007, China.
    Escin, a triterpene saponin isolated from horse chestnut seed, has been used to treat encephaledema, tissue swelling and chronic venous insufficiency. Recent studies show that escin induces cell cycle arrest, tumor proliferation inhibition and tumor cell apoptosis. But the relationship between escin-induced DNA damage and cell apoptosis in tumor cells remains unclear. Read More

    Clinically Meaningful Differences on Symptoms Associated Chronic Venous Disease in Response to a Cooling Treatment Compared to Placebo: A Randomized Clinical Trial.
    J Wound Ostomy Continence Nurs 2018 May 24. Epub 2018 May 24.
    Teresa J. Kelechi, PhD, RN, College of Nursing, Medical University of South Carolina, Charleston. Mary J. Dooley, MS, College of Nursing, Medical University of South Carolina, Charleston. Martina Mueller, PhD, College of Nursing, Medical University of South Carolina, Charleston. Mohan Madisetti, MS, College of Nursing, Medical University of South Carolina, Charleston. Margie A. Prentice, MBA, College of Nursing, Medical University of South Carolina, Charleston.
    Purpose: The purpose of this study was to examine the efficacy of a self-administered cooling treatment on clinically meaningful differences (CMDs) in symptom changes in patients with chronic venous disease.

    Design: Blinded, prospective, randomized controlled trial.

    Subjects And Setting: Two hundred seventy-six community-dwelling adults 21 years and older with skin changes and/or a healed venous leg ulcer (Clinical-Etiologic-Anatomic-Pathologic [CEAP] 4 and 5 classification) completed the 6-month active treatment period. Read More

    A Rare Case of Lemierre-Like Syndrome: A Case Report and Literature Review.
    Case Rep Pediatr 2018 1;2018:9613493. Epub 2018 Apr 1.
    Pediatrics Department, Pediatric Infectious Diseases Division, Tawam Hospital, Al Ain, UAE.
    Lemierre's syndrome (LS) is a serious rare complication of oropharyngeal infections. It is characterized by thrombosis of internal jugular vein that rapidly progresses into sepsis and is typically caused by anaerobes. Most of the reported cases have been linked to ; however, there are a handful of reported cases due to aerobes. Read More

    Clinical Pharmacology of Oral Anticoagulants in Patients with Kidney Disease.
    Clin J Am Soc Nephrol 2018 May 25. Epub 2018 May 25.
    Division of Nephrology, Department of Internal Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama; and
    Oral anticoagulants are commonly used drugs in patients with CKD and patients with ESKD to treat atrial fibrillation to reduce stroke and systemic embolism. Some of these drugs are used to treat or prevent deep venous thrombosis and pulmonary embolism in patients with CKD who undergo knee and hip replacement surgeries. Warfarin is the only anticoagulant that is approved for use by the Food and Drug Administration in individuals with mechanical heart valves. Read More

    Report of a man with heterotopic ossification of the legs.
    Reumatol Clin 2018 May 21. Epub 2018 May 21.
    Servicio de Radiodiagnóstico, Hospital General Universitario de Ciudad Real, Ciudad Real, España.
    Heterotopic ossification is an uncommon disorder that consists of deposition of ectopic bone outside the extraskeletal tissues. In the skin, it can be primary, in association with genetic syndromes, or be secondary to different disorders. The latter include subcutaneous ossification of the legs in chronic venousinsufficiency, an infrequent and unrecognized complication. Read More

    Venous leg symptoms in patients with varicocele: A multicenter assessment study (VEIN-TURKEY study).
    Phlebology 2018 Jan 1:268355518777110. Epub 2018 Jan 1.
    10 Private Yenisehir Hospital, Department of Cardiology, Mersin, Turkey.
    Objective The aim of this study is to evaluate chronic venous disease symptoms by using the Venous Insufficiency Epidemiological and Economic Study-Quality of Life/Symptoms (VEINES-QoL/Sym) questionnaire in varicocele patients. Material and methods The study was designed as a prospective, case controlled study and conducted in four hospitals from Turkey. A total of 600 patients who admitted to urology outpatient clinic were enrolled to the study. Read More

    Extracorporeal membrane oxygenation support in individuals with thoracic insufficiency.
    Perfusion 2018 May 1:267659118778173. Epub 2018 May 1.
    3 Division of Pediatric Critical Care, Department of Pediatrics, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
    Introduction: Respiratory failure is the leading cause of mortality in individuals with congenital spine and rib deformities. We present a case report of a child with Jeune syndrome surviving respiratory failure using extracorporeal membrane oxygenation (ECMO). We also summarize thoracic insufficiency syndrome cases reported in the Extracorporeal Life Support Organization (ELSO) registry. Read More

    A systematic review on the use of deep venous stenting for acute venous thrombosis of the lower limb.
    Phlebology 2018 Jan 1:268355518772760. Epub 2018 Jan 1.
    1 Academic Section of Vascular Surgery, Department of Surgery and Cancer, Imperial College London, Charing Cross Hospital, London, UK.
    Objectives The aim is to evaluate venous stent patency, the development of post-thrombotic syndrome, recurrence, quality of life and the optimal post-procedural anticoagulation regimen in the treatment of iliofemoral deep venous thrombosis. Method and results EMBASE and Medline databases were interrogated to identify studies in which acute deep venous thrombosis patients were stented. Twenty-seven studies and 542 patients were identified. Read More

    The effect of increasing catheter distance from the deep junction on the outcomes of radiofrequency vein ablation.
    J Vasc Surg Venous Lymphat Disord 2018 May 18. Epub 2018 May 18.
    Section of Vascular Surgery, Department of Surgery, Yale School of Medicine, New Haven, Conn. Electronic address:
    Objective: Thermal vein ablation (VA) is the recommended treatment modality for superficial venous reflux, with a recommended positioning of the catheter at 2 to 3 cm from the junction of the deep venous system. In contrast, novel sealing technology for saphenous VA involves treatment starting at 3 to 5 cm distal to the deep junction. This study examines the effect of increasing catheter distance from the junction on the outcomes of VA using radiofrequency. Read More

    Endovenous Thermal Ablation of Recurrent Varicose Veins due to Residual Great Saphenous Venous Insufficiency After Saphenous Venous Surgery: A Comparative Study.
    Dermatol Surg 2018 May 16. Epub 2018 May 16.
    All authors are affiliated with the Department of Radiology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of Korea.
    Background: Redo surgery for recurrent varicose veins of the great saphenous vein (GSV) is technically more challenging than the initial surgery.

    Objective: To compare 980 and 1,470-nm endovenous laser ablation (EVLA) and radiofrequency ablation (RFA) for the treatment of residual GSV insufficiency after saphenofemoral ligation ± stripping.

    Materials And Methods: Thirty-seven limbs in 29 patients with recurrent varicose veins were retrospectively evaluated. Read More

    [Improving outcomes of patients with heterotaxy and functional single ventricle: a 10-year follow-up of 70 cases in a single institution].
    Zhonghua Wai Ke Za Zhi 2018 May;56(5):379-385
    Department of Cardiac Surgery, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, China.
    To review current-era palliation outcomes of patients with heterotaxy and functional single ventricle in a single institution. The clinical data of 70 consecutive patients with heterotaxy undergoing multistage single ventricle palliation in Guangzhou Women and Children's Medical Center from January 2008 to December 2017 were retrospectively reviewed, and the prognosis factors for mortality were analyzed. There were 53 male and 17 female patients. Read More

    Is May-Thurner Syndrome Combined with Left Iliac Arteriovenous Fistularare or Neglected?: Cases Report and Literature Review.
    Ann Vasc Surg 2018 May 17. Epub 2018 May 17.
    Department of Vascular Surgery, YanTai Yuhuangding Hospital, YanTai, ShanDong, China. Electronic address:
    May-Thurner syndrome (MTS) is a condition in which the left common iliac vein is compressed by the right common iliac artery, which may cause swelling, pain or deep venous thrombosis of the left lower extremity. Postthrombotic syndrome, nonthrombotic chronic venous insufficiency, and recurrence after venous thrombosis are also possible complications. Although MTS combined with left iliac arteriovenous fistula is rarely reported, we treated 3 such cases in the past year. Read More

    Recanalization After Endovenous Thermal Ablation.
    Ann Vasc Surg 2018 May 17. Epub 2018 May 17.
    Vascular Institute of New York, Brooklyn, NY.
    Background: Endovenous thermal ablation in the form of radiofrequency ablation (RFA) or endovenous laser ablation (EVLA) has quickly ascended to a prime position in the treatment of venous insufficiency. Although there are good data examining the rates of thrombotic complications, there is a relative paucity of data examining the recanalization rates after endovenous thermal ablation (ETA).

    Methods: Data analysis was performed for 1475 thermal ablations in 485 patients from 2012 to 2015 as a retrospective chart review. Read More

    Underexpansion of Wallstents in the Treatment of Nonthrombotic Iliac Vein Lesions.
    Ann Vasc Surg 2018 May 17. Epub 2018 May 17.
    Vascular Institute of New York, Brooklyn, NY.
    Background: Iliac vein stenting is increasingly being used in the treatment of chronic venous insufficiency for patients with nonthrombotic iliac vein lesions (NIVL). We have noticed that many stents do not deploy to the expected stent area (ESA) as designated by the manufactured stent diameter (MSD). The purpose of this study was to evaluate the dynamics of Wallstent expansion in the iliocaval system. Read More

    Improved Prognosis and Low Failure Rate with Anticoagulation as First-Line Therapy in Mesenteric Venous Thrombosis.
    World J Surg 2018 May 17. Epub 2018 May 17.
    Department of Clinical Sciences, Lund University, Malmö, Sweden.
    Background: Monotherapy with anticoagulation has been considered as first-line therapy in patients with mesenteric venous thrombosis (MVT). The aim of this study was to evaluate outcome, prognostic factors, and failure rate of anticoagulation as monotherapy, and to identify when bowel resection was needed.

    Methods: Retrospective study of consecutive patients with MVT diagnosed between 2000 and 2015. Read More

    [Modern treatment of mesenteric ischemia].
    Presse Med 2018 Jun;47(6):519-530
    AP-HP, hôpital Beaujon, structure d'urgence vasculaire intestinale (SURVI), service de gastroentérologie, MICI et assistance nutritive, 100, boulevard du Général-Leclerc, 92100 Clichy, France; Université Sorbonne-Paris Cité, 2, rue Albert-Einstein, 75013 Paris, France; Hôpital Bichat, Laboratory for Vascular Translationnal Science, Inserm U1148, 75018 Paris, France.
    Acute mesenteric ischemia is a highly morbid affliction which requires urgent care. Acute mesenteric ischemia consists in an ischemia injury of the small bowel, secondary to vascular insufficiency, either occlusive (thrombosis, embolism, arterial, venous) or non-occlusive (low flow or vasospasm). Given that the superior mesenteric artery supplies the small bowel as well as the right part of the colon, any ischemic process involving the right colon should be considered an acute mesenteric ischemia until proven otherwise. Read More

    Use of Polidocanol endovenous microfoam to improve hemodynamics and symptomology in patients with challenging clinical presentations: A case series.
    Ann Vasc Surg 2018 May 14. Epub 2018 May 14.
    OhioHealth Vascular Institute, OhioHealth Heart and Vascular Physicians, Columbus, OH. Electronic address:
    Background: We performed a retrospective review of treatment effects with FDA-approved Polidocanol endovenous microfoam (PEM, Varithena® 1%) on venous symptomology in ten (N=10) C3-C6 patients with chronic venous insufficiency (CVI) and concomitant complex disease/pathology that limited the use of endothermal ablation (ETA).

    Methods: Pathology included: risk of bruising or bleeding, severe lipodermatosclerosis (LDS), Hydradenitis Suppurativa, chronic fibrosis of the vein from prior superficial thrombosis, risk for nerve injury and failed prior ETA. Pre-treatment, all patients underwent a venous incompetence study using duplex ultrasound (DUS). Read More

    Resilience, trust, and civic engagement in the post-CCSVI era.
    BMC Health Serv Res 2018 May 16;18(1):366. Epub 2018 May 16.
    Division of Neurology, Department of Medicine, University of British Columbia, Vancouver, Illinois, Canada.
    Background: Scientific and financial investments in chronic cerebrospinal venous insufficiency (CCSVI) research have been made to address both the hope for and scepticism over this interventional strategy for MS. Despite limited evidence in support of the CCSVI hypothesis, the funding of clinical research was responsive to a demand by the public rarely seen in the history of medicine. We characterize patient perspectives about the CCSVI research trajectory, with particular attention to its impact on other non-pharmaceutical areas of MS research with a focus on stem cell interventions. Read More

    Clinical outcomes after varicose vein procedures in octogenarians within the Vascular Quality Initiative Varicose Vein Registry.
    J Vasc Surg Venous Lymphat Disord 2018 Jul 8;6(4):464-470. Epub 2018 May 8.
    Section of Vascular Surgery, University of Michigan Medical School, Ann Arbor, Mich.
    Background: Whereas chronic venous insufficiency and varicose veins (VVs) are a universally recognized problem, they are frequently underappreciated as major contributors to long-term morbidity in the elderly despite the increasing prevalence with age. Previous studies have demonstrated that chronic venous insufficiency and VV treatments in patients ≥65 years old yield an overall benefit; however, there have been few data as to whether octogenarians are undergoing these procedures and with what success. As such, our objectives were to investigate the procedures selected, to examine clinical outcomes after VV procedures in elderly patients ≥80 years old, and to explore complication rates (both systemic and leg specific) after VV procedures in patients ≥80 years old. Read More

    Peripheral vascular disease assessment in the lower limb: a review of current and emerging non-invasive diagnostic methods.
    Biomed Eng Online 2018 May 11;17(1):61. Epub 2018 May 11.
    The MARCS Institute for Brain, Behaviour & Development, Western Sydney University, Penrith, NSW, 2750, Australia.
    Background: Worldwide, at least 200 million people are affected by peripheral vascular diseases (PVDs), including peripheral arterial disease (PAD), chronic venous insufficiency (CVI) and deep vein thrombosis (DVT). The high prevalence and serious consequences of PVDs have led to the development of several diagnostic tools and clinical guidelines to assist timely diagnosis and patient management. Given the increasing number of diagnostic methods available, a comprehensive review of available technologies is timely in order to understand their limitations and direct future development effort. Read More

    The Impact of Microbial Communities on Wound Healing: A Review.
    Ann Plast Surg 2018 Jul;81(1):113-123
    From the Section of Plastic Surgery, Department of Surgery, Yale University School of Medicine, New Haven, CT.
    Chronic, nonhealing wounds place an enormous burden on both the health care system and patients, with no definitive treatments available. There has been increasing evidence that the microbial composition of wounds may play an important role in wound healing. Culture-independent methods for bacterial detection and analysis have revealed the wound microbiome to be much more diverse and complex than culture alone. Read More

    Insufficiency of the zona glomerulosa of the adrenal cortex and progressive kidney insufficiency following unilateral adrenalectomy - case report and discussion.
    Blood Press 2018 May 9:1-9. Epub 2018 May 9.
    a Department of Hypertension and Diabetology, Faculty of Medicine , Medical University of Gdansk , Gdansk , Poland.
    Background: Primary aldosteronism (PA) is the most common cause of secondary hypertension and bilateral adrenal hyperplasia (BAH) and aldosterone-producing adenoma (APA) seem to be the most common causes of PA. Unilateral adrenalectomy (UA) is the preferred treatment for APA, although the benefits are still difficult to assess.

    Case Report: We present a case report of a 69-year old man with a 30 year history of hypertension and probably long-standing PA due to APA, with typical organ complications. Read More

    Prevalence of Central Vein Stenosis in Patients Referred for Vein Mapping.
    Clin J Am Soc Nephrol 2018 May 8. Epub 2018 May 8.
    Division of Nephrology.
    Background And Objectives: Central vein stenosis is considered to be common in patients on hemodialysis but its exact prevalence is not known. In this study, we report the prevalence of central vein stenosis in patients with CKD referred for vein mapping.

    Design, Setting, Participants, & Measurements: We conducted a retrospective study of adult patients who had bilateral upper extremity venographic vein mapping from September 1, 2011 to December 31, 2015. Read More

    The relationship of multiple sclerosis and cerebral developmental venous anomaly with an advantageous role in the multiple sclerosis diagnosis.
    Iran J Neurol 2017 Oct;16(4):168-172
    Autoimmune Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
    There is a suggestion for a role of abnormal cranial venous drainage in the etiopathogenesis of multiple sclerosis (MS). Moreover, it seems that cerebral developmental venous anomaly (DVA), a cerebrovascular malformation, is frequently seen in the magnetic resonance imaging (MRI) of MS patients. This study is set out to evaluate the relationship between MS and cerebral DVA, with its possible role in the MS diagnosis. Read More

    Cognitive Impairment in Non-Dialysis-Dependent CKD and the Transition to Dialysis: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study.
    Am J Kidney Dis 2018 May 2. Epub 2018 May 2.
    Geriatric Research and Education Clinical Center, VA Palo Alto, Palo Alto, CA; Stanford University School of Medicine, Palo Alto, CA.
    Background: Advanced chronic kidney disease is associated with elevated risk for cognitive impairment. However, it is not known whether and how cognitive impairment is associated with planning and preparation for end-stage renal disease.

    Study Design: Retrospective observational study. Read More

    Effect of Sildenafil on Pulmonary Circulation and Cardiovascular Function in Near-Term Fetal Sheep During Hypoxemia.
    Reprod Sci 2018 Jan 1:1933719118773412. Epub 2018 Jan 1.
    1 Women's Health & Perinatal Research Group, Department of Clinical Medicine, UiT-The Arctic University of Norway, Tromsø, Norway.
    Sildenafil is a potential new treatment for placental insufficiency in human pregnancies as it reduces the breakdown of vasodilator nitric oxide. Pulmonary vasodilatation is observed in normoxemic fetuses following sildenafil administration. Placental insufficiency often leads to fetal hypoxemia that can cause pulmonary vasoconstriction and fetal cardiac dysfunction as evidenced by reduced isovolumic myocardial velocities. Read More

    Effect of Resident Involvement on Morbidity and Mortality Following Thoracic Endovascular Aortic Repair.
    J Surg Educ 2018 Apr 27. Epub 2018 Apr 27.
    Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:
    Objective: To evaluate the effect of resident involvement in thoracic endovascular aortic repair (TEVAR).

    Summary Of Background Data: Although the influence of resident intraoperative involvement in several types of surgical procedures has been reported, the effect of resident participation in TEVAR is unknown. We evaluated patient outcomes in resident-involved TEVAR procedures. Read More

    Total Endovascular Iliocaval Reconstruction Using Polytetrafluoroethylene Stent-Graft Placement for the Treatment of Inferior Vena Cava Resection.
    Cardiovasc Intervent Radiol 2018 Jul 27;41(7):1116-1120. Epub 2018 Apr 27.
    Department of Radiology, Division of Vascular and Interventional Radiology, University of Michigan Health Systems, 1500 East Medical Center Drive, Ann Arbor, MI, 48109, USA.
    Resection of the inferior vena cava (IVC) is a rare surgical technique that is occasionally combined with nephrectomy in the setting of renal malignancy with intravascular tumor extension. While this may be fairly well tolerated in some patients due to extensive collateralization in the venous system, there is a clear potential for lower extremity venous insufficiency and deep vein thrombosis (DVT). This report describes a patient who underwent right nephrectomy and segmental IVC resection from the subhepatic space to the iliac confluence, which was complicated by profoundly symptomatic lower extremity DVT and gastrointestinal hemorrhage due to system-to-portal shunting. Read More

    A case report regarding general anesthesia management of a patient with pulmonary vein stenosis that underwent balloon dilatation and stent implantation.
    Medicine (Baltimore) 2018 Apr;97(17):e0429
    Department of Anesthesiology, West China Hospital, Sichuan University.
    Rationale: Pulmonary vein stenosis (PVS) is a rare cardiovascular deformity that can lead to high mortality if left untreated. Patients frequently experience multiple complications such as hemoptysis, pulmonary hypertension, bronchial venous rupture and cardiac insufficiency. Currently, pulmonary vein stenosis balloon dilatation (stent implantation) is the only treatment, and this can be performed under local or general anesthesia. Read More

    The femoral vein diameter and its correlation with sex, age and body mass index - An anatomical parameter with clinical relevance.
    Phlebology 2018 Jan 1:268355518772746. Epub 2018 Jan 1.
    1 Department of Anatomy, 39071 Rostock University Medical Center , Rostock, Germany.
    Background The femoral vein diameter is a critical factor when assessing endoprosthetic valve size for the treatment of chronic venous insufficiency. To examine the previously stated correlation between body mass index and femoral vein diameter and to re-assess the anatomical and physiological demands for a valve implant for chronic venous insufficiency treatment, we measured the femoral vein diameter in 82 subjects. Method Femoral vein diameters (164 legs) were measured with B-mode sonography both in supine position at rest and in upright position during Valsalva maneuver. Read More

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