Search our Database of Scientific Publications and Authors

I’m looking for a

    12328 results match your criteria Venous Insufficiency

    1 OF 247

    Anticoagulation manager: development of a clinical decision support mobile application for management of anticoagulants.
    Conf Proc IEEE Eng Med Biol Soc 2016 Aug;2016:2582-2585
    Patients with certain clotting disorders or conditions have a greater risk of developing arterial or venous clots and downstream embolisms, strokes, and arterial insufficiency. These patients need prescription anticoagulant drugs to reduce the possibility of clot formation. However, historically, the clinical decision making workflow in determining the correct type and dosage of anticoagulant(s) is part science and part art. Read More

    Study on Mucin in Normal-Appearing Leg Skin.
    Am J Dermatopathol 2017 Mar;39(3):163-170
    Consultant Histopathologist, Department of Cellular Pathology, Hospital El Bierzo, Ponferrada, Spain.
    Dermal deposits of mucin in the legs have been described associated with venous insufficiency. However, some degree of stasis dermatitis is generally common in aged individuals. Therefore, some amount of mucin is expected a priori in the reticular dermis of aged patients, even in the absence of clinical lesions. Read More

    Clinical and epidemiological assessment of patients hospitalized for primary and recurrent erysipelas
    Przegl Epidemiol 2016 ;70(4):575-584
    Medical University of Bialystok, Poland; Department of Dermatology and Venereology
    Introduction: Erysipelas is a bacterial infection, caused by group A β-hemolytic streptococci (Streptococcus pyogenes), rarely other bacteria. It is characterized by sudden onset and rapid course, with the presence of systemic symptoms.

    Objective: A retrospective analysis of patients hospitalized for primary and recurrent erysipelas with particular consideration of clinical profile of patients, causes, complications and risk factors of the recurrence. Read More

    Internal iliac venous aneurysm associated with pelvic venous insufficiency.
    J Vasc Surg Venous Lymphat Disord 2017 Mar 25;5(2):257-260. Epub 2016 Jul 25.
    Division of Vascular Surgery, University of Michigan, Ann Arbor, Mich. Electronic address:
    Aneurysmal disease of the internal iliac vein is rare, with no standard indication for or accepted modality of treatment. Here we report an instance of unilateral, primary left internal iliac venous aneurysm and associated pelvic venous insufficiency. Following extensive workup for alternative causes, the aneurysm and left gonadal vein were coil embolized with good effect. Read More

    The value of near-infrared spectroscopy for the assessment of calf muscle function in venous patients.
    J Vasc Surg Venous Lymphat Disord 2017 Mar 28;5(2):244-253. Epub 2016 Feb 28.
    Department of Vascular Surgery, University of Athens Medical School, "Attikon" University Hospital, Athens, Greece.
    Objective: Near-infrared spectroscopy (NIRS) is a noninvasive technique with the potential to determine the degree of tissue oxygenation. The aim of the current study was to investigate the use of NIRS as a reliable method of detecting calf muscle pump dysfunction in groups of patients with venous disease.

    Methods: Patients with superficial venous insufficiency (SVI) or history of deep venous thrombosis (DVT) were classified according to the comprehensive classification system for chronic venous disorders (clinical class, etiology, anatomy, and pathophysiology) and compared with controls (GROUP variable). Read More

    Relationship between patient-reported symptoms, limitations in daily activities, and psychological impact in varicose veins.
    J Vasc Surg Venous Lymphat Disord 2017 Mar;5(2):224-237
    BTG International Inc, West Conshohocken, Pa.
    Objective: The objective of this study was to evaluate the relationship between patient-reported symptoms, functional limitations, and psychological impact of varicose veins (VVs) vs pathophysiologic mechanism, incorporating demographic and behavioral factors.

    Methods: We conducted a pooled analysis from two clinical studies (Efficacy and Safety Study of Polidocanol Injectable Foam for the Treatment of Saphenofemoral Junction Incompetence [VANISH-1] and Polidocanol Endovenous Microfoam Versus Vehicle for the Treatment of Saphenofemoral Junction Incompetence [VANISH-2]) in patients with VVs (superficial venous reflux only). Health outcomes were classified on the basis of the Wilson-Cleary conceptual framework continuum linking clinical and anatomic factors (Clinical, Etiology, Anatomy, and Pathophysiology [CEAP] clinical class and great saphenous vein [GSV] diameter, respectively) to patient-reported outcomes: Varicose Vein Symptoms Questionnaire (VVSymQ) score; modified Venous Insufficiency Epidemiologic and Economic Study on Quality of Life/Symptoms (m-VEINES-QOL/Sym) limitations in daily activities (functional limitations hereafter) score; and m-VEINES-QOL/Sym psychological impact score. Read More

    Ablation of the great saphenous vein with nontumescent n-butyl cyanoacrylate versus endovenous laser therapy.
    J Vasc Surg Venous Lymphat Disord 2017 Mar 12;5(2):210-215. Epub 2017 Jan 12.
    Department of Cardiovascular Surgery, Cerrahpaşa Medical Faculty, Istanbul University, Istanbul, Turkey.
    Objective: The endovenous application of n-butyl cyanoacrylate (NBCA) is a new nontumescent ablation technique for the treatment of venous insufficiency. The aim of this study was to retrospectively compare an NBCA-based ablation method with endovenous laser ablation (EVLA) for the management of incompetent great saphenous veins.

    Methods: Between May 2013 and August 2014, there were 339 patients with incompetent varicose veins who were treated with either the endovenous application of NBCA (VariClose Vein Sealing System [VVSS]; Biolas, Ankara, Turkey) or EVLA. Read More

    Radiofrequency ablation with concomitant stab phlebectomy increases risk of endovenous heat-induced thrombosis.
    J Vasc Surg Venous Lymphat Disord 2017 Mar;5(2):200-209
    Department of Surgery, Johns Hopkins Vein Center, Johns Hopkins Medical Centers, Baltimore, Md. Electronic address:
    Objective: Endovenous heat-induced thrombosis (EHIT) is a well-documented phenomenon that follows endovenous ablation, but the treatment, surveillance, and risk factors for EHIT have yet to be comprehensively elucidated. We sought to identify characteristics that may put patients at higher risk for development of EHIT after radiofrequency ablation (RFA) for the treatment of symptomatic superficial venous insufficiency.

    Methods: A retrospective review was performed of all consecutive patients undergoing treatment with RFA to the great saphenous vein by a single surgeon from July 2013 through October 2015. Read More

    Recommendations for the medical management of chronic venous disease: The role of Micronized Purified Flavanoid Fraction (MPFF).
    Phlebology 2017 Apr;32(1_suppl):3-19
    6 Extrapolate LLC, USA.
    Scope A systematic review of the clinical literature concerning medical management of chronic venous disease with the venoactive therapy Micronized Purified Flavonoid Fraction was conducted in addition to an investigation of the hemodynamics and mechanism of chronic venous disease. Methods The systematic review of the literature focused on the use of Micronized Purified Flavonoid Fraction (diosmin) which has recently become available in the US, in the management of chronic venous disease. The primary goal was to assess the level of evidence of the role of Micronized Purified Flavonoid Fraction in the healing of ulcers, and secondarily on the improvement of the symptoms of chronic venous disease such as edema. Read More

    The current spectrum of contact sensitization in patients with chronic leg ulcers or stasis dermatitis - new data from the Information Network of Departments of Dermatology (IVDK).
    Contact Dermatitis 2017 Feb 14. Epub 2017 Feb 14.
    Department of Dermatology, University Hospital Erlangen, 91054, Erlangen, Germany.
    Background: Patients with lower leg dermatitis, chronic venous insufficiency or chronic leg ulcers have a high prevalence of contact sensitization.

    Objectives: To identify the current spectrum of contact allergens in these patients.

    Patients And Methods: Data of the Information Network of Departments of Dermatology on 5264 patients with the above diagnoses from the years 2003 to 2014 (study group) were compared with data on 4881 corresponding patients from 1994 to 2003 (historical control group) and with a current control group without these diagnoses (n = 55 510). Read More

    Italian intersociety consensus on DOAC use in internal medicine.
    Intern Emerg Med 2017 Feb 13. Epub 2017 Feb 13.
    Department of Internal Medicine and Medical Specialties, "La Sapienza" University of Rome, Rome, Italy.
    The direct oral anticoagulants (DOACs) are drugs used in clinical practice since 2009 for the prevention of stroke or systemic embolism in non-valvular atrial fibrillation, and for the treatment and secondary prevention of venous thromboembolism. The four DOACs, including the three factor Xa inhibitors (rivaroxaban, apixaban and edoxaban) and one direct thrombin inhibitor (dabigatran) provide oral anticoagulation therapy alternatives to Vitamin K antagonists (VKAs). Despite their clear advantages, the DOACs require on the part of the internist a thorough knowledge of their pharmacokinetic and pharmacodynamic characteristics to ensure their correct use, laboratory monitoring and the appropriate management of adverse events. Read More

    What's the remedy for the distal necrosis of DIEP flap, better venous drain or more arterial supply?
    PLoS One 2017 10;12(2):e0171651. Epub 2017 Feb 10.
    Shanghai Ninth People's Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
    Background: We developed a novel pedicled DIEP flap model in rat to explore the possible remedy for the distal necrosis of the flap.

    Methods: A deep inferior epigastric perforator (DIEP) flap, based on the second right cranial perforator (P2) as the main pedicle, was elevated in 48 Sprague-Dawley rats. The rats were randomized into 4 groups: group I, the left P2 remaining intact as supercharging; group II, the left P2 artery alone kept as supercharging; group III, the left P2 vein alone kept as supercharging; group IV, no supercharging. Read More

    The importance of great saphenous vein types and segmental aplasia in venous reflux.
    J Clin Ultrasound 2017 Feb 10. Epub 2017 Feb 10.
    GOP Taksim Training and Research Hospital, Radiology, Istanbul, Turkey.
    Purpose: To investigate the relationship among great saphenous vein (GSV) anatomic type, segmental aplasia, and reflux.

    Methods: Color Doppler ultrasonography (CDUS) was performed on 475 legs of 277 consecutive patients with venous symptoms between November 2015 and August 2016. Exclusion criteria were previous venous surgery and venous thrombosis. Read More

    Comparison of Phenylephrine and Ephedrine in Treatment of Spinal-Induced Hypotension in High-Risk Pregnancies: A Narrative Review.
    Front Med (Lausanne) 2017 20;4. Epub 2017 Jan 20.
    Department of Anesthesiology, The Ohio State University Wexner Medical Center , Columbus, OH , USA.
    Purpose: To compare maternal and fetal effects of intravenous phenylephrine and ephedrine administration during spinal anesthesia for cesarean delivery in high-risk pregnancies.

    Source: An extensive literature search was conducted using the US National Library of Medicine, MEDLINE search engine, Cochrane review, and Google Scholar using search terms "ephedrine and phenylephrine," "preterm and term and spinal hypotension," "preeclampsia and healthy parturients," or "multiple and singleton gestation and vasopressor." Society of Obstetric Anesthesia and Perinatology meeting abstracts for the past 4 years were also searched for relevant studies. Read More

    Calcium Dobesilate Prevents Diabetic Kidney Disease by Decreasing Bim and Inhibiting Apoptosis of Renal Proximal Tubular Epithelial Cells.
    DNA Cell Biol 2017 Feb 2. Epub 2017 Feb 2.
    3 Department of Medicine, Division of Endocrinology, Shandong Provincial Qianfoshan Hospital, Shandong University , Jinan, China .
    Apoptosis of renal proximal tubular epithelial cells (PTECs) plays a vital role in the pathogenesis and progression of diabetic kidney disease (DKD). Calcium dobesilate is a vascular protective compound used for treatment of diabetic retinopathy and chronic venous insufficiency. The aim of this study was to determine whether calcium dobesilate can protect PTECs from glucose-induced apoptosis and the potential mechanism of this effect. Read More

    Portal vein stent placement for the treatment of postoperative portal vein stenosis: long-term success and factor associated with stent failure.
    BMC Surg 2017 Feb 1;17(1):11. Epub 2017 Feb 1.
    Department of General Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670, Japan.
    Background: Portal vein stenosis develops due to different causes including postoperative inflammation and oncological processes. However, limited effective therapy is available for portal vein stenosis. The objectives of this study were to evaluate the efficacy of a portal vein stent for portal vein stenosis after hepatobiliary pancreatic surgery and to determine the factors associated with stent patency. Read More

    Endovenous laser ablation in patients with severe primary chronic venous insufficiency.
    Int Angiol 2017 Jan 31. Epub 2017 Jan 31.
    Novosibirsk State Budget Research Institute of Circulation Pathology, Ministry for Public Healthcare of Russian Federation, Novosibirsk, Russia.
    Background: The aim of study was to estimate the safety and efficacy of using laser wavelength of 1560 nm with the foam sclerotherapy (FS) of varicose veins (VVs) for the treatment of severe primary chronic venous insufficiency (CVI, C4-C6) in patients with different diameters of the proximal segment (DPS) of the great saphenous vein (GSV).

    Methods: We have separated the patients into two groups depending on the size of GSV: group 1 (281 cases; DPS of GSV less than 15 mm) and group 2 (210 cases; DPS of GSV more than 15 mm). Both groups received the endovenous laser ablation (EVLA) of the saphenous vein trunk, incompetent perforator veins (IPs) and FS (Tessari method) of VVs. Read More

    [Estimation of poor prognostic factors in patients with pulmonary artery thromboembolism].
    Ter Arkh 2016 ;88(12):28-32
    Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Seiences, Tomsk, Russia.
    Aim: To identify predictors of fatal outcome in hospitalized patients with risk factors (RF) for pulmonary artery thromboembolism (PATE) during its occurrence.

    Subjects And Methods: To determine predictors of fatal outcome in patients with PATE, the data of a 10-year city hospital pulmonary embolism registry were used to analyze RF for PATE (according to European and Russian guidelines), complaints, medical histories, and laboratory and instrumental data, which can be identified at general surgery or general therapy hospital, as well as a nosological entity existing in the patients.

    Results: According to the existing idea on thrombogenesis, RF for PATE and its fatal outcome, information about used treatment, and autopsy data, 137 parameters were selected in patients with PATE. Read More

    [Venous aneurysms associated with lymphatic malformations].
    Cir Pediatr 2016 Apr 10;29(2):77-81. Epub 2016 Apr 10.
    Servicio de Cirugía Pediátrica, Sección de Cirugía plástica. Hospital Universitario La Paz. Madrid.
    Objectives: To analyze and describe the association between the development of venous aneurysms of the mayor vessels in patients with lymphatic malformations.

    Material And Methods: Retrospective review of patients diagnosed with both VA and LM from 1993 to 2014 and a descriptive analysis of clinical course was performed.

    Results: We found 6 patients, 50% females, who had LM and VA confirmed with imaging techniques. Read More

    New Insights in the Pathophysiology of Antiphospholipid Syndrome.
    Semin Thromb Hemost 2017 Jan 27. Epub 2017 Jan 27.
    Department of Pediatrics, Center for Pulmonary and Vascular Biology, University of Texas Southwestern Medical Center, Dallas, Texas.
    The antiphospholipid syndrome (APS) is an autoimmune disorder characterized by an elevated risk for arterial and venous thrombosis and pregnancy-related morbidity. Since the discovery of the disease in 1980s, numerous studies in cell culture systems, in animal models, and in patient populations have been reported, leading to a deeper understanding of the pathogenesis of APS. These studies have determined that circulating autoantibodies, collectively called antiphospholipid antibodies (aPL), the majority of which recognize cell surface proteins attached to the plasma membrane phospholipids, play a causal role in the development of the disease. Read More

    Measures of Kidney Disease and the Risk of Venous Thromboembolism in the REGARDS (Reasons for Geographic and Racial Differences in Stroke) Study.
    Am J Kidney Dis 2017 Jan 23. Epub 2017 Jan 23.
    Larner College of Medicine, University of Vermont, Burlington, VT.
    Background: Kidney disease has been associated with venous thromboembolism (VTE) risk, but results conflict and there is little information regarding blacks.

    Study Design: Prospective cohort study.

    Setting & Participants: 30,239 black and white adults 45 years or older enrolled in the REGARDS (Reasons for Geographic and Racial Differences in Stroke) Study 2003 to 2007. Read More

    Minimally invasive treatments for perforator vein insufficiency.
    Cardiovasc Diagn Ther 2016 Dec;6(6):593-598
    Division of Interventional Radiology, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
    Incompetent superficial veins are the most common cause of lower extremity superficial venous reflux and varicose veins; however, incompetent or insufficient perforator veins are the most common cause of recurrent varicose veins after treatment, often unrecognized. Perforator vein insufficiency can result in pain, skin changes, and skin ulcers, and often merit intervention. Minimally invasive treatments have replaced traditional surgical treatments for incompetent perforator veins. Read More

    Sudden death by rupture of a varicose vein: Case report and review of literature.
    Med Leg J 2017 Mar 15;85(1):47-50. Epub 2016 Nov 15.
    Institute of Legal Medicine, University Magna Graecia of Catanzaro, Catanzaro, Italy.
    Venous disease, including varicose veins and chronic venous insufficiency, is one of the most common chronic medical conditions. Haemorrhage from rupture of varicose veins in the legs is rare and can lead to sudden death. Nevertheless, this condition is not included among the causes of sudden death. Read More

    Purple, stiff lesions resembling varicose veins on lower limb: certainly consider Kaposi sarcoma.
    Kardiochir Torakochirurgia Pol 2016 Dec 30;13(4):380-382. Epub 2016 Dec 30.
    Department of Cardiovascular Surgery, Gülhane Military Medical Academy, Etlik, Ankara, Turkey.
    Kaposi's sarcoma (KS) typically presents multiple cutaneous lesions of the lower extremities. Lesions can rarely mimic varicose veins without venous insufficiency, vascular or stasis ulcers. As the initial diagnosis of KS is generally determined clinically, a high index of suspicion and palpation of lesions are necessary for all patients with atypical presentations of varicose-like lesions of lower extremities. Read More

    Impact of UK NICE clinical guidelines 168 on referrals to a specialist academic leg ulcer service.
    Phlebology 2017 Jan 1:268355516688357. Epub 2017 Jan 1.
    1 Department of Vascular Surgery, University of Birmingham, Netherwood House, Solihull Hospital, Birmingham, UK.
    Background Leg ulcers are a common cause of morbidity and disability and result in significant health and social care expenditure. The UK National Institute for Health and Care Excellence (NICE) Clinical Guideline (CG)168, published in July 2013, sought to improve care of patients with leg ulcers, recommending that patients with a break in the skin below the knee that had not healed within two weeks be referred to a specialist vascular service for diagnosis and management. Aim Determine the impact of CG168 on referrals to a leg ulcer service. Read More

    [The influence of the training of the muscular component of the musculo-venous pump in the lower extremities on the clinical course of varicose vein disease].
    Vopr Kurortol Fizioter Lech Fiz Kult 2016 ;93(6):33-36
    State Budgetary Educational Institution of Higher Professional Education 'Samara State Medical University', Russian Ministry of Health, Samara, Russia.
    Investigations of the influence of the training of the muscular component of the musculo-venous pump in the lower extremities on the clinical course of varicose vein disease and correction of the step cycle are currently underway.

    Aim: The objective of the present study was to evaluate the impact of the training of the muscular component of the musculo-venous pump in the lower extremities and of the correction of the step cycle on the quality of life of the patients presenting with varicose vein disease.

    Material And Methods: The study included 22 patients with varicose veins in the lower extremities (CEAP clinical class C3 or C4). Read More

    Metabolic profiles of exudates from chronic leg ulcerations.
    J Pharm Biomed Anal 2017 Apr 10;137:13-22. Epub 2017 Jan 10.
    Department of Pharmaceutical Microbiology and Parasitology, Wrocław Medical University, Borowska 211A Str., 50-556 Wrocław, Poland.
    Chronic leg ulceration is a disease usually associated with other comorbidities, and significantly reduces patient quality of life. Infected leg ulcers can lead to limb-threatening sequelae or mortality. Leg ulcerations are colonized by a number of microbes that are able to cause life-threating infections in susceptible patients. Read More

    Stasis Dermatitis: Pathophysiology, Evaluation, and Management.
    Am J Clin Dermatol 2017 Jan 6. Epub 2017 Jan 6.
    Department of Dermatology, University of Texas McGovern Medical School at Houston, 6655 Travis St, Ste 980, Houston, TX, 77030, USA.
    Stasis dermatitis commonly occurs in older age. It is caused by venous hypertension resulting from retrograde flow due to incompetent venous valves, valve destruction, or obstruction of the venous system. Further tissue changes arise from an inflammatory process mediated by metalloproteinases, which are up-regulated by ferric ion from extravasated red blood cells. Read More

    Clinical Characteristics of Mixed Arteriovenous Leg Ulcers: A Descriptive Study.
    J Wound Ostomy Continence Nurs 2017 Jan/Feb;44(1):41-47
    Joseph A. Marin, BScH, BNSc, RN, School of Nursing, Faculty of Health Sciences, Queen's University, Kingston, Ontario, Canada. Kevin Y. Woo, PhD, RN, FAPWCA, School of Nursing, Faculty of Health Sciences, Queen's University, Kingston, Ontario, Canada.
    Purpose: The purpose of this study was to identify the clinical characteristics of mixed arteriovenous leg ulcers (MLU) that differentiated them from venous leg ulcers (VLU).

    Design: Secondary analysis of data from larger electronic database.

    Subjects And Setting: The sample comprised 1007 persons with lower extremity ulcers. Read More

    [Vitamin K antagonists : Is their prescription really "medical malpractice" today?]
    Internist (Berl) 2017 Jan;58(1):90-99
    3. Medizinische Abteilung (Kardiologie, Pneumologie und Internistische Intensivmedizin), Asklepios Klinik Altona, Paul-Ehrlich-Str. 1, 22763, Hamburg, Deutschland.
    Atrial fibrillation and venous thromboembolisms are frequent cardiovascular diseases. Until a few years ago only vitamin K antagonists (VKA) were available for oral anticoagulation as primary and secondary prevention of thrombembolic events. Currently, the non-vitamin K dependent new oral anticoagulants (NOAC) dabigatran, rivaroxaban, apixaban and edoxaban are approved for use. Read More

    Utility of Adjunctive Digital Subtraction Venography for the Treatment of Saphenous Vein Insufficiency.
    J Endovasc Ther 2017 Jan 1:1526602816686734. Epub 2017 Jan 1.
    1 Department of Vascular Surgery, Prince of Wales Hospital, Sydney, Australia.
    Purpose: To report the use of adjunctive venography for the treatment of superficial venous reflux.

    Methods: Two hundred consecutive patients (mean age 60.9 years, range 33-86; 128 women) with chronic venous disease underwent saphenous or perforator vein ablation in 268 limbs (305 venous trunks) guided by adjunctive venography and fluoroscopy in addition to ultrasound between October 2010 and May 2016. Read More

    Technique, Efficiency and Safety of Different Nerve Blocks for Analgesia in Laser Ablation and Sclerotherapy for Lower Limb Superficial Venous Insufficiency - A Multicentre Experience.
    J Clin Diagn Res 2016 Nov 1;10(11):TC13-TC17. Epub 2016 Nov 1.
    Consultant Interventional and Cardiac Radiologist, Radiology, Ramesh Hospitals , Guntur, Andhra Pradesh, India .
    Introduction: Laser ablation and sclerotherapy, as minimally invasive alternatives to surgery for varicose veins, have good efficacy, safety and cosmetic result. Some form of anaesthesia is generally used for pain control.

    Aim: To describe the technique and evaluate the efficacy and safety of femoral, saphenous and sciatic nerve blocks in isolation or in combination for analgesia during laser ablation and sclerotherapy for lower limb varicose veins. Read More

    Comparison of heat induced damage at the saphenofemoral junction after ablation with 1,470 nm laser or radiofrequency.
    Vasa 2017 Jan 3:1-7. Epub 2017 Jan 3.
    4 Diskapi Yildirim Beyazid Training and Research Hospital, Cardiovascular Surgery, Ankara, Turkey.
    Background: The aim of this study was to evaluate the heat induced damage at the saphenofemoral junction level according to histopathological changes after radiofrequency or 1,470 nm radial tip laser ablation.

    Patients And Methods: Varicose vein segments of 6-10 mm in diameter were exposed to radiofrequency (Closure Fast catheter, 7 cm heat segment, one cycle, 15 seconds, 10 Watt, 120 °C) or laser ablation (1,470 nm radial tip, continuous wave, vein diameter: 6 cm/8 cm/10 cm-power: 10 Watt-pullback speed: 2.2 mm/s, 1. Read More

    The Prevalence of Chronic Cerebrospinal Venous Insufficiency in Meniere Disease: 24-Month Follow-up after Angioplasty.
    J Vasc Interv Radiol 2017 Mar 27;28(3):388-391. Epub 2016 Dec 27.
    Sense Organs Department, Sapienza University, Rome, Italy.
    Purpose: To evaluate relationship between Meniere disease (MD) and chronic cerebrospinal venous insufficiency (CCSVI) using ultrasound, magnetic resonance (MR) imaging, and venography and to evaluate the effectiveness of angioplasty of the internal jugular vein (IJV) and azygos vein (AV) in reducing symptoms of MD.

    Materials And Methods: Patients with a confirmed diagnosis of MD unresponsive to standard treatment underwent duplex ultrasound and MR imaging to diagnose CCSVI. Healthy volunteers were also studied to evaluate CCSVI in asymptomatic subjects. Read More

    Experimental Rat Skin Flap Model That Distinguishes between Venous Congestion and Arterial Ischemia: The Reverse U-Shaped Bipedicled Superficial Inferior Epigastric Artery and Venous System Flap.
    Plast Reconstr Surg 2017 Jan;139(1):79e-84e
    Tokyo, Japan From the Department of Plastic, Reconstructive, and Aesthetic Surgery, Nippon Medical School; and the Department of Pathology and the Department of Integrated Diagnostic Pathology, Graduate School of Medicine, Nippon Medical School Hospital.
    Background: The commonly used flap models have drawbacks that limit their usefulness. In the random skin flap model, flap necrosis is caused by both arterial and venous insufficiency. In the axial skin flap model, flap viability is easily affected by the pedicle blood flow and can result in complete necrosis. Read More

    Catheter-directed thrombolysis and pharmacomechanical thrombectomy improve midterm outcome in acute iliofemoral deep vein thrombosis.
    J Chin Med Assoc 2017 Feb 23;80(2):72-79. Epub 2016 Dec 23.
    Division of Cardiovascular Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC; National Defense Medical Center, Taipei, Taiwan, ROC. Electronic address:
    Background: Aggressive and early thrombus removal strategy has been widely used as a treatment for iliofemoral deep vein thrombosis (DVT). We compared the long-tem venous outcome, including postthrombotic syndrome (PTS), in patients undergoing catheter-directed thrombolysis (CDT) and pharmacomechanical thrombectomy (PMT).

    Methods: From January 2009 to December 2013, 61 patients with acute proximal DVT were enrolled in this prospective study. Read More

    Advanced Chronic Venous Insufficiency.
    Vasc Endovascular Surg 2017 Jan 26;51(1):12-16. Epub 2016 Dec 26.
    2 Division of Vascular Surgery, Department of Surgery, Johns Hopkins Vein Center, Johns Hopkins Medical Institutions, Baltimore, MD, USA.
    Introduction: Intervention for advanced chronic venous insufficiency is considered an appropriate standard of care. However, outcomes vary among patients who present in advanced clinical stages of disease. The main objectives of this study were to determine whether racial disparity exists at initial presentation and response to intervention. Read More

    Insufficient Lymph Drainage Causes Abnormal Lipid Accumulation and Vein Wall Degeneration.
    Ann Vasc Dis 2016 1;9(4):277-284. Epub 2016 Dec 1.
    Division of Vascular Surgery, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.
    Objective: Previously, we analyzed human varicose veins (VV) using imaging mass spectrometry (IMS) and detected the abnormal accumulation of lipid molecules in the walls of VV, possibly due to insufficient lipid drainage by the lymphatic vessels. In this study, we created an animal model of lymphatic insufficiency to investigate the effects of insufficient lymph drainage on vein walls. Methods: In rats, the lymphatic collecting vessels surrounding the femoral vein were ligated on one side (the model tissue), which caused the local retention of lymphatic fluid in the perivascular tissue. Read More

    Mesenteric ischemia following the correction of adult spinal deformity: case report.
    J Neurosurg Spine 2016 Dec 23:1-4. Epub 2016 Dec 23.
    Department of Orthopaedic Surgery, University of California, San Francisco, California.
    Vascular complications are an important adverse event that can be associated with spinal reconstructive surgery. Direct injury of vessels, or indirect traction or compression of vessels, can cause both arterial and venous injury. Indirect compression of the mesenteric vessels is a well-recognized complication of bracing and surgical care of children with spinal deformity (superior mesenteric artery syndrome), but the complication is not common or well recognized in the adult population with spinal deformity. Read More

    Effect of socio-demographic characteristics and clinical findings on the quality of life of patients with chronic venous insufficiency.
    Vascular 2016 Jan 1:1708538116685945. Epub 2016 Jan 1.
    3 Department of Social Work, Faculty of Health Science, Celal Bayar University, Manisa, Turkey.
    Objective This study was planned and implemented to evaluate the effect of socio-demographic characteristics and clinical findings on the quality of life of patients with chronic venous insufficiency. Methods The sample of this cross-sectional study consisted of 163 patients that presented with the diagnosis of chronic venous insufficiency to the cardiovascular surgery clinic of an education and research hospital in the west of Turkey. The data were collected during face-to-face interviews using a personal information form, clinical, etiology, anatomy, pathophysiology classification, venous insufficiency epidemiological and economic study-quality of life/symptoms scales and the Short Form-36. Read More

    Angiopoietin receptor Tie2 is required for vein specification and maintenance via regulating COUP-TFII.
    Elife 2016 Dec 22;5. Epub 2016 Dec 22.
    Cyrus Tang Hematology Center, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China.
    Mechanisms underlying the vein development remain largely unknown. Tie2 signaling mediates endothelial cell (EC) survival and vascular maturation and its activating mutations are linked to venous malformations. Here we show that vein formation are disrupted in mouse skin and mesentery when Tie2 signals are diminished by targeted deletion of Tek either ubiquitously or specifically in embryonic ECs. Read More

    Early severe acute respiratory distress syndrome: What's going on? Part II: controlled vs. spontaneous ventilation?
    Anaesthesiol Intensive Ther 2016 ;48(5):339-351
    Physiology, Claude Bernard University, University of Lyon, Lyon, France.
    The second part of this overview on early severe ARDS delineates the pros and cons of the following: a) controlled mechanical ventilation (CMV: lowered oxygen consumption and perfect patient-to-ventilator synchrony), to be used during acute cardio-ventilatory distress in order to "buy time" and correct circulatory insufficiency and metabolic defects (acidosis, etc.); b) spontaneous ventilation (SV: improved venous return, lowered intrathoracic pressure, absence of muscle atrophy). Given a stabilized early severe ARDS, as soon as the overall clinical situation improves, spontaneous ventilation will be used with the following stringent conditionalities: upfront circulatory optimization, upright positioning, lowered VO2, lowered acidotic and hypercapnic drives, sedation without ventilatory depression and without lowered muscular tone, as well as high PEEP (titrated on transpulmonary pressure, or as a second best: "trial"-PEEP) with spontaneous ventilation + pressure support (or newer modes of ventilation). Read More

    Comparative Study of Outcome of Duplex Ultrasound-Guided, Catheter-Directed Foam Sclerotherapy and Radio-frequency Ablation in the Management of Great Saphenous Varicose Veins.
    Indian J Surg 2016 Oct 25;78(5):375-381. Epub 2016 Apr 25.
    Department of Surgery, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, 110029 India.
    Chronic venous insufficiency of lower limbs is a common problem in adults. We compared the two modalities, namely duplex ultrasound-guided, catheter-directed foam sclerotherapy (UGFS) and radio-frequency ablation (RFA), in the management of great saphenous varicose veins using clinical assessment (Venous Clinical Severity Score, Venous Disability Score) and duplex imaging. Patients presenting with great saphenous vein (GSV) varicosity due to incompetent saphenofemoral junction (SFJ) were selected and randomly assigned in each arm, i. Read More

    A Prospective Study in Comparison of Ambulatory Phlebectomy and Duplex Guided Foam Sclerotherapy in the Management of Varicosities with Isolated Perforator Incompetence.
    Indian J Surg 2016 Oct 16;78(5):356-363. Epub 2016 May 16.
    Institute of General Surgery, Rajiv Gandhi Government General Hospital, Chennai, 600003 Tamilnadu India.
    Perforators are those which connect the superficial and deep venous system either directly to main veins or indirectly through the muscular and soleal venous plexus. The emergence of minimally invasive techniques like ambulatory phlebectomy (AP) and foam sclerotherapy (FS) has led to increasing interest about the appropriate therapy for the treatment of isolated perforator incompetence. There have been no studies which have compared the effectiveness of these in-office procedures in isolated perforator incompetence due to the low prevalence of cases. Read More

    Iliofemoral Venous Thrombosis Mainly Related to Iliofemoral Venous Obstruction by External Tumor Compression in Cancer Patients.
    Case Rep Oncol 2016 Sep-Dec;9(3):760-771. Epub 2016 Nov 18.
    Division of Hemato-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Taoyuan, Taiwan.
    Background: To study iliofemoral venous thrombosis related to iliofemoral venous obstruction in cancer patients.

    Methods: In this case series study, 829 cancer patients were surveyed for iliofemoral obstruction/thrombosis within 10 years. The criteria for inclusion were: (1) presence of unilateral lower-extremity swelling; (2) computed tomography (CT) scans showing a tumor with external compression of the iliac or femoral vein, and (3) duplex ultrasound scans showing venous thrombosis or venous flow insufficiency over a femoral vein or saphenous vein. Read More

    Differentiation of functional venous insufficiency and leg lymphedema complicated by functional venous insufficiency using subcutaneous tissue ultrasonography.
    J Vasc Surg Venous Lymphat Disord 2017 Jan 28;5(1):96-104. Epub 2016 Sep 28.
    Department of Surgery and Clinical Science, Division of Vascular Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan.
    Objective: To use subcutaneous ultrasonography to differentiate legs with edema because of obesity-related functional venous insufficiency (FVIob), immobility-related FVI (FVIim), secondary lymphedema (LE), LE complicated by obesity (LEob), and LE complicated by immobility (LEim).

    Methods: Ninety-nine legs with edema (16 FVIob, 32 FVIim, 22 LE, 9 LEob, and 20 LEim), and 10 normal legs were examined. Subcutaneous tissue ultrasonography was performed at eight points (medial, lateral, upper, lower, thigh, and calf) in each leg. Read More

    Determining the origin of superficial venous reflux in the groin with duplex ultrasound and implications for varicose vein surgery.
    J Vasc Surg Venous Lymphat Disord 2017 Jan;5(1):82-86
    Department of Dermatology, Ruhr-University Bochum, Bochum, Germany.
    Objective: The purpose of this paper was to describe patterns of superficial reflux in the groin with respect to the terminal valve (TV), which is located at the saphenous opening to the common femoral vein, the great saphenous vein, and its tributary veins.

    Methods: This study included 2019 legs with chronic venous insufficiency that received endoluminal varicose vein treatment because of varicosities with insufficiency of the saphenofemoral junction (SFJ). In a preoperative duplex ultrasound investigation of the superficial vein system, reflux after provocation in the SFJ, great saphenous vein, cranial veins (superficial external pudendal vein, superficial epigastric vein, superficial circumflex iliac vein), and anterior and posterior accessory saphenous veins was recorded and classified on the basis of the origin of reflux. Read More

    Common femoral endovenectomy in conjunction with iliac vein stenting to improve venous inflow in severe post-thrombotic obstruction.
    J Vasc Surg Venous Lymphat Disord 2017 Jan 26;5(1):138-142. Epub 2016 Sep 26.
    Narayana Institute of Cardiac Sciences, Narayana Healthcare, Bangalore, India. Electronic address:
    Post-thrombotic syndrome secondary to iliofemoral deep venous thrombosis is a significant contributor to advanced chronic venous insufficiency. Iliac vein stenting is a standard procedure to treat iliocaval obstruction. In cases with obstruction extending across the groin, venous inflow for an iliac vein stent may be poor and compromise results of iliac vein stenting. Read More

    1 OF 247