13,378 results match your criteria Venous Insufficiency


Comparison of venous repair results using either arterial or vein grafts in a crush-avulsion injury model

Turk J Med Sci 2019 Feb 11;49(1):435-441. Epub 2019 Feb 11.

Background/aim: Venous insufficiency after replantation or revascularization is one of the most common causes of limb loss in either the short or the long term. The aim of this study was to evaluate the results of a new technique to overcome venous insufficiency.

Materials And Methods: A crush-avulsion type of injury was formed in the femoral veins of rats of 3 separate groups. Read More

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http://dx.doi.org/10.3906/sag-1808-38DOI Listing
February 2019

Intracellular Streptococcal Uptake and Persistence: A Potential Cause of Erysipelas Recurrence.

Front Med (Lausanne) 2019 29;6. Epub 2019 Jan 29.

Department of Dermatology, University Clinics, Ludwig-Maximilian University of Munich, Munich, Germany.

Erysipelas is a severe streptococcal infection of the skin primarily spreading through the lymphatic vessels. Penicillin is the treatment of choice. The most common complication consists in relapses which occur in up to 40% or more of patients despite appropriate antibiotic treatment. Read More

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https://www.frontiersin.org/article/10.3389/fmed.2019.00006/
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http://dx.doi.org/10.3389/fmed.2019.00006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361840PMC
January 2019
1 Read

Micronized Purified Flavonoid Fraction (MPFF) for Patients Suffering from Chronic Venous Disease: A Review of New Evidence.

Authors:
Jorge H Ulloa

Adv Ther 2019 Feb 13. Epub 2019 Feb 13.

Fundación Santa Fe de Bogotá, Universidad de Los Andes, Bogotá, Colombia.

Chronic venous disease (CVD) is both prevalent and unavoidable in many people as a result of persistent or unalterable risk factors, the most important of which are advanced age, excess body weight, and family history. Given this inevitability, medical treatment is required to alleviate symptoms and slow disease progression. Venoactive drug therapy is emerging as a valuable treatment option for many CVD patients and micronized purified flavonoid fraction (MPFF) is the most widely prescribed and well-studied venoactive drug available. Read More

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http://dx.doi.org/10.1007/s12325-019-0884-4DOI Listing
February 2019

How Does Chronic Venous Disease Progress from the First Symptoms to the Advanced Stages? A Review.

Adv Ther 2019 Feb 13. Epub 2019 Feb 13.

Department of Surgery, Stony Brook University Medical Center, Stony Brook, NY, USA.

Risk factors for the development of progression chronic venous disease (CVD) and varicose veins are widespread and include advanced age, excess body weight, sedentary lifestyles and occupations, family history, and pregnancy. Varicose veins and CVD are associated with venous hypertension, venous reflux, dysfunctional venous valves, and vein wall inflammation, though the precise etiologies are unclear. Once venous pathology develops, it can progress through a vicious cycle of inflammation and leukocyte recruitment that leads to further deterioration of vein walls and valves, increased hypertension, and release of additional proinflammatory mediators. Read More

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http://dx.doi.org/10.1007/s12325-019-0885-3DOI Listing
February 2019

Burden and Suffering in Chronic Venous Disease.

Adv Ther 2019 Feb 13. Epub 2019 Feb 13.

Department of Surgery, Stony Brook University Medical Center, Stony Brook, NY, USA.

Chronic venous disease (CVD) is widespread, underdiagnosed, and can progress to chronic venous insufficiency and venous ulcers, which can require extensive treatment and hospitalization. These conditions negatively impact patient quality of life and place substantial burdens on healthcare resources. The two main risk factors for CVD are age and obesity. Read More

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http://dx.doi.org/10.1007/s12325-019-0882-6DOI Listing
February 2019

The Seriousness of Chronic Venous Disease: A Review of Real-World Evidence.

Authors:
Alun H Davies

Adv Ther 2019 Feb 13. Epub 2019 Feb 13.

Academic Section of Vascular Surgery, Department of Surgery and Cancer, Imperial College London, Charing Cross Hospital, London, UK.

Chronic venous disease (CVD) is a prevalent condition that tends to worsen with age. Patients initially seek treatment to relieve symptoms of leg pain, discomfort, heaviness and swelling, all of which impact their quality of life. As the disease increases in severity to include varicose veins, skin changes, and venous ulcer, the demand for treatment increases while the quality of life further diminishes. Read More

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http://dx.doi.org/10.1007/s12325-019-0881-7DOI Listing
February 2019

[Diagnosis of pulmonary embolism].

Rev Med Interne 2019 Feb 8. Epub 2019 Feb 8.

Département de médecine, institut de recherche de l'hôpital d'Ottawa, Ottawa, Canada.

The diagnosis of pulmonary embolism (PE) is nowadays based on the sequential use of several diagnostic tests rather than on a single test. These diagnostic strategies are safe and have been prospectively validated. The first step after identifying patients with suspicion of PE is to establish the pre-test clinical probability. Read More

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http://dx.doi.org/10.1016/j.revmed.2019.01.004DOI Listing
February 2019

Two-year follow-up of a n-butyl-2-cyanoacrylate glue ablation for the treatment of saphenous vein insufficiency with a novel application catheter with guiding light.

Authors:
Atilla Sarac

Vascular 2019 Feb 10:1708538118823838. Epub 2019 Feb 10.

Department of Cardiovascular Surgery, VM Medical Park Samsun Hospital, Samsun, Turkey.

Objectives: This study aims to present the early results of a prospective study of the use of novel n-butyl-2 cyanoacrylate (VenaBlock)-based nontumescent endovenous ablation with a guiding light for the treatment of patients with varicose veins.

Methods: Five hundred and seventy-three patients with lower-limb venous insufficiency were treated within in the previous four years. The study enrolled adults aged 21-70 years with symptomatic moderate to severe varicosities (C2-C6 patients clinical, etiological, anatomical, and pathophysiological classification) and great saphenous vein reflux lasting longer than 0. Read More

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http://dx.doi.org/10.1177/1708538118823838DOI Listing
February 2019
1 Read

Revascularization surgery for symptomatic non-moyamoya intracranial arterial stenosis or occlusion.

J Neurosurg 2019 Feb 8:1-6. Epub 2019 Feb 8.

2Department of Clinical Medicine, Macquarie University; and.

OBJECTIVEPrevious trials rejected a role of extracranial-to-intracranial bypass surgery for managing symptomatic atheromatous disease. However, hemodynamic insufficiency may still be a rationale for surgery, provided the bypass can be performed with low morbidity and patency is robust.METHODSConsecutive patients undergoing bypass surgery for symptomatic non-moyamoya intracranial arterial stenosis or occlusion were retrospectively identified. Read More

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http://dx.doi.org/10.3171/2018.9.JNS181075DOI Listing
February 2019

Chronic lower extremity wounds in a patient with Klippel Trenaunay syndrome.

J Vasc Surg Cases Innov Tech 2019 Mar 28;5(1):45-48. Epub 2019 Jan 28.

Department of Surgery, Atlantic Health System Morristown Medical Center, Morristown, NJ.

Klippel-Trenaunay syndrome is a rare disorder consisting of the triad of vascular and/or lymphatic malformations, capillary malformations, and soft tissue or bony hypertrophy. Symptom control is the mainstay of treatment for these patients, with many of the symptoms never fully being relieved. In this case report, we present the case of a 46-year-old man with chronic lower extremity ulcerations unresponsive to wound care therapy. Read More

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http://dx.doi.org/10.1016/j.jvscit.2018.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355325PMC
March 2019
1 Read

Paradigm shift in geriatric fracture treatment.

Eur J Trauma Emerg Surg 2019 Feb 6. Epub 2019 Feb 6.

Department of Orthopaedics and Traumatology, University Medical Center of Johannes Gutenberg-University Mainz, Mainz, Germany.

The number of geriatric patients is increasing. These patients exhibit specific characteristics, which influence the type of fracture care. Many patients have comorbidities, which make them more vulnerable to surgical procedures. Read More

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http://dx.doi.org/10.1007/s00068-019-01080-xDOI Listing
February 2019
1 Read

Diagnosis and treatment of acquired arteriovenous fistula after lower extremity deep vein thrombosis.

Int Angiol 2019 Feb 5. Epub 2019 Feb 5.

Department of Vascular Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China -

Background: Deep vein thrombosis (DVT) is a rare cause of arteriovenous fistula (AVF). The pathogenesis of acquired AVF after DVT remains unclear, and publications focusing on therapy and follow-up are also inadequate. In this study, the diagnosis and treatment of 24 patients with acquired AVF in the lower extremity after DVT was reported. Read More

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http://dx.doi.org/10.23736/S0392-9590.19.04063-XDOI Listing
February 2019
1 Read

Complex liver resection under hepatic vascular exclusion and hypothermic perfusion with versus without veno-venous bypass: a comparative study.

HPB (Oxford) 2019 Feb 2. Epub 2019 Feb 2.

Department of Hepato-Pancreatico-Biliary Surgery and Liver Transplant, Hôpital Beaujon, Assistance Publique-Hôpitaux de Paris, 100 Boulevard du Général Leclerc, 92110, Clichy, France(4). Electronic address:

Background: While hypothermic liver perfusion has been shown to improve parenchymal tolerance to complex resections in patients requiring prolonged hepatic vascular exclusion (HVE), the benefit of associated veno-venous bypass (VVB) in this setting remains poorly evaluated.

Methods: All patients undergoing liver resection requiring HVE and hypothermic liver perfusion for at least 55 min between 2006 and 2017 were retrospectively reviewed. Perioperative outcomes were compared between patients with (VVB+) or without VVB (VVB-). Read More

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http://dx.doi.org/10.1016/j.hpb.2018.12.012DOI Listing
February 2019
1 Read

Mechanical Ventilation and Extracorporeal Membrane Oxygena tion in Acute Respiratory Insufficiency.

Dtsch Arztebl Int 2018 12;115(50):840-847

Board of directors, Ulm University Hospital

Background: Mechanical ventilation is life-saving for patients with acute respiratory insufficiency. In a German prevalence study, 13.6% of patients in intensive care units received mechanical ventilation for more than 12 hours; 20% of these patients received mechanical ventilation as treatment for acute respiratory distress syndrome (ARDS). Read More

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http://dx.doi.org/10.3238/arztebl.2018.0840DOI Listing
December 2018
2 Reads

Factors Influencing Elastographically Determined Remodeling of Venous Thrombi.

J Ultrasound Med 2019 Feb 4. Epub 2019 Feb 4.

Department of Plastic Surgery, Orłowski Hospital, Center of Postgraduate Medical Education, Warsaw, Poland.

Objectives: To verify whether elastographically determined remodeling of venous obliterating material formed during sclerotherapy is influenced by patient-specific factors.

Methods: The study included 60 patients who underwent sclerotherapy for venous insufficiency. Elastographic parameters of obliterating material, including relative vascular cross sections (percent) with the highest (red), intermediate (green), and lowest elasticity (blue), determined 7 ± 1, 14 ± 2, and 21 ± 2 days after sclerotherapy, were analyzed against the patients' ages, sexes, physical activity levels, and pain severities. Read More

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http://dx.doi.org/10.1002/jum.14965DOI Listing
February 2019
1 Read

Anticoagulation in Cancer Patients: a Summary of Pitfalls to Avoid.

Curr Oncol Rep 2019 Feb 4;21(2):18. Epub 2019 Feb 4.

Taussig Cancer Institute, Cleveland Clinic, 10201 Carnegie Ave./CA60, Cleveland, OH, 44195, USA.

Purpose Of Review: Venous thromboembolism (VTE) is a leading cause of morbidity and mortality in cancer patients, and its management is often associated with complications including risk of recurrent VTE and bleeding. Here, we review the current data on pitfalls during anticoagulation in cancer patients and measures necessary to avoid them.

Recent Findings: Although low-molecular-weight heparin monotherapy has been the standard of treatment for several years, emerging data for direct oral anticoagulants (DOACs) are leading to new paradigms in treatment. Read More

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http://dx.doi.org/10.1007/s11912-019-0767-5DOI Listing
February 2019
1 Read

Hypertensive choroidopathy: Multimodal imaging and the contribution of wide-field swept-source oct-angiography.

Am J Ophthalmol Case Rep 2019 Mar 9;13:131-135. Epub 2019 Jan 9.

Department of Ophthalmology, Croix-Rousse University Hospital, Hospices Civils de Lyon, Lyon, France.

Purpose: To present the case of a patient with a hypertensive choroidopathy and her follow-up using multimodal imaging; and to assess how wide-field swept-source (SS) Optical Coherence Tomography Angiography (OCTA) contributes to detecting the areas of hypoperfusion.

Observations: A 25-year-old white woman with terminal renal insufficiency, myopericarditis, and cerebrospinal fluid pressure of 37 mmHg indicating intracranial hypertension, presented with a painless loss of vision in both eyes. Her blood pressure was 190/135 mmHg. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348489PMC
March 2019
1 Read

Panniculitis in rheumatology: features of course and outcomes.

Ter Arkh 2018 May;90(5):55-60

V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia.

Aim: The study of the course and outcomes of panniculitis (PN) in modern rheumatology practice.

Materials And Methods: We observed 209 patients (pts) (f-185, m-24 in age 17 to 80 years) with the input diagnosis "Erythema nodosum? Undifferentiated panniculitis?" and duration of illness in from 1 week to 25 years, observed in V.A. Read More

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http://dx.doi.org/10.26442/terarkh201890555-60DOI Listing
May 2018
1 Read

Exercise and Chronic Wound Healing.

Authors:
Laura Bolton

Wounds 2019 Feb;31(2):65-67

Department of Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ.

The calf muscles have been called the body's "second heart," improving blood circulation when exercised, usually by walking. Structured exercise training (SET) increases calf muscle pump function, lower limb circulation, and walking capacity for those with limited ambulation due to peripheral arterial disease (PAD)1 or venous insufficiency.2 This resulted in the Centers for Medicare and Medicaid Services (CMS) decision to reimburse up to thirty-six 30- to 60-minute, properly supervised hospital outpatient or office-based SET sessions over 12 weeks to treat intermittent claudication for patients with PAD. Read More

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February 2019
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Endovenous cyanoacrylate glue to treat varicose veins and chronic venous insufficiency-Experience gained from our first 100+ truncal venous ablations in a multi-ethnic Asian population using the Medtronic VenaSeal™ Closure System.

Phlebology 2019 Jan 28:268355519826008. Epub 2019 Jan 28.

2 Department of General Surgery, Changi General Hospital, Singapore.

Objectives: The aim of this prospective single-centre study is to assess the effectiveness and patient experience of the VenaSeal™ Closure System, a novel non-thermal, non-tumescent catheter technique, which uses cyanoacrylate glue to occlude the refluxing truncal superficial veins to treat varicose veins and chronic venous insufficiency, in a multi-ethnic Asian population from Singapore.

Methods: Seventy-seven patients (93 legs; 103 procedures) underwent VenaSeal™ Closure System ablation. Forty-nine (63. Read More

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http://dx.doi.org/10.1177/0268355519826008DOI Listing
January 2019
1 Read

The comparative analysis of non-thrombotic internal jugular vein stenosis and cerebral venous sinus stenosis.

J Thromb Thrombolysis 2019 Jan 28. Epub 2019 Jan 28.

Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.

Internal jugular vein (IJV) stenosis and cerebral venous sinus (CVS) stenosis belong to cerebral venous outflow insufficiency. This study aimed to analyze the similarities and differences between IJV stenosis and CVS stenosis. Patients with either IJV stenosis or CVS stenosis confirmed by contrast-enhanced magnetic resonance venography between October 2017 and July 2018 were enrolled in this retrospective study. Read More

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http://dx.doi.org/10.1007/s11239-019-01820-1DOI Listing
January 2019

Persistent disparities in breast cancer surgical outcomes among hispanic and African American patients.

Eur J Surg Oncol 2019 Jan 17. Epub 2019 Jan 17.

Yale School of Medicine, Department of Surgery, Section of Plastic and Reconstructive Surgery, New Haven, CT, USA. Electronic address:

Background: Racial disparities among patients who receive breast mastectomy and reconstruction have not been well characterized.

Methods: Records of patients undergoing breast extirpative and reconstructive surgery at a high-volume university-affiliated hospital over 5 consecutive years were reviewed. Patient demographics, breast cancer profiles, reconstructive modality, and outcomes were compared by race. Read More

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http://dx.doi.org/10.1016/j.ejso.2019.01.016DOI Listing
January 2019
7 Reads

Interleukin-6 and amyotrophic lateral sclerosis.

J Neurol Sci 2019 Jan 16;398:50-53. Epub 2019 Jan 16.

Institute of Physiology and Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Portugal; Department of Neurosciences and Mental Health, Hospital de Santa Maria-CHLN, Lisbon, Portugal. Electronic address:

Background: IL-6 is an inflammatory cytokine that is a possible factor in progression of the disease. We have investigated venous blood levels of IL-6 in controls and ALS patients in relation to clinical staging and respiratory function.

Methods: We studied 82 patients with ALS and 43 age and gender-matched healthy control subjects. Read More

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http://dx.doi.org/10.1016/j.jns.2019.01.026DOI Listing
January 2019
1 Read

Controlling compression bandaging pressure in leg ulcer research trials: A summary of the literature.

Phlebology 2019 Jan 24:268355519825590. Epub 2019 Jan 24.

3 Sir Charles Gairdner Hospital, Perth, WA, Australia.

Compression bandaging remains the 'gold standard' intervention for the treatment of venous leg ulcers. Numerous studies have investigated the effect of a large variety of compression bandaging techniques and materials on venous leg ulcer healing. However, the majority of these studies failed to monitor both actual bandage application pressures and the bandaging competency of participating clinicians. Read More

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http://dx.doi.org/10.1177/0268355519825590DOI Listing
January 2019
2 Reads

Clinical, ultrasonographic and histological findings in varicose vein surgery.

Rev Assoc Med Bras (1992) 2018 Aug;64(8):729-735

. Medical Science Faculty of the Santa Casa of São Paulo, São Paulo/SP, Brasil.

Objective: This study aims to correlate the demographic data, different clinical degrees of chronic venous insufficiency (CEAP), ultrasound findings of saphenofemoral junction (SFJ) reflux, and anatomopathological findings of the proximal segment of the great saphenous vein (GSV) extracted from patients with primary chronic venous insufficiency (CVI) submitted to stripping of the great saphenous vein for the treatment of lower limb varicose.

Method: This is a prospective study of 84 patients (110 limbs) who were submitted to the stripping of the great saphenous vein for the treatment of varicose veins of the lower limbs, who were evaluated for CEAP clinical classification, the presence of reflux at the SFJ with Doppler ultrasonography, and histopathological changes. We study the relationship between the histopathological findings of the proximal GSV withdrawal of patients with CVI with a normal GSV control group from cadavers. Read More

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
Publisher Site
http://dx.doi.org/10.1590/1806-9282.64.08.729DOI Listing
August 2018
4 Reads

Clinical Manifestations of Superior Mesenteric Venous Thrombosis in the Era of Computed Tomography.

Vasc Specialist Int 2018 Dec 31;34(4):83-87. Epub 2018 Dec 31.

Department of Surgery, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.

Purpose: Thrombosis of the portal vein, known as pylephlebitis, is a rare and fatal complication caused by intraperitoneal infections. The disease progression of superior mesenteric venous thrombosis (SMVT) is not severe. This study aimed to determine the clinical features, etiology, and prognosis of SMVT. Read More

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http://www.vsijournal.org/journal/DOIx.php?id=10.5758/vsi.20
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http://dx.doi.org/10.5758/vsi.2018.34.4.83DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340699PMC
December 2018
3 Reads

The microbiome and its relevance in complex wounds.

Eur J Dermatol 2019 Jan 21. Epub 2019 Jan 21.

University of Genoa, Dissal, Department of Dermatology, San Martino Policlinic Hospital, Genoa, Italy.

Chronic wounds include arterial, venous, diabetic and pressure ulcers. The term "chronic wound" defines wounds that have not healed within three months. The possible causes that transform a simple wound into a chronic one are the object of study, and research has focused on infection as one of the crucial factors in producing and maintaining chronic wounds. Read More

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http://dx.doi.org/10.1684/ejd.2018.3486DOI Listing
January 2019
4 Reads

Treatments to prevent primary venous ulceration after deep venous thrombosis.

J Vasc Surg Venous Lymphat Disord 2019 Jan 16. Epub 2019 Jan 16.

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Fla. Electronic address:

Objective: This systematic review and meta-analysis aimed to assess whether compression stockings or other interventions reduce the incidence of venous ulceration after acute deep venous thrombosis.

Methods: We searched PubMed and Embase for randomized controlled trials (RCTs), restricted to English, Spanish, and Hebrew, related to post-thrombotic syndrome and venous ulceration in participants with confirmed deep venous thrombosis. Our primary statistical assessment was the Peto odds ratio (OR). Read More

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http://dx.doi.org/10.1016/j.jvsv.2018.12.009DOI Listing
January 2019

Penile Doppler ultrasonography and elastography evaluation in patients with erectile dysfunction.

Pol J Radiol 2018 3;83:e491-e499. Epub 2018 Dec 3.

Atatürk Training and Research Hospital, Urology, Ankara, Turkey.

Purpose: To evaluate the relationship between erection grade, erectile function score, Doppler ultrasonography (US) indexes, and elasticity score (ES) according to Doppler US diagnosis in patients with erectile dysfunction (ED).

Material And Methods: Real-time strain type penile elastography was performed during penile Doppler US examination for 88 patients with ED. The diagnosis according to Doppler US was determined. Read More

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http://dx.doi.org/10.5114/pjr.2018.80301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334185PMC
December 2018
1 Read

Twelve-month efficacy and complications of cyanoacrylate embolization compared with radiofrequency ablation for incompetent great saphenous veins.

J Vasc Surg Venous Lymphat Disord 2019 Jan 14. Epub 2019 Jan 14.

Department of Cardiovascular Surgery, Medical School of Eskişehir Osmangazi University, Eskişehir, Turkey.

Objective: In this study, the clinical results of radiofrequency ablation (RFA) and n-butyl-cyanoacrylate embolization (CAE) methods were compared in the treatment of incompetent great saphenous veins (GSVs).

Methods: We analyzed retrospectively 244 patients (128 patients in the RFA group, 116 patients in the CAE group) with incompetent GSVs who were treated with RFA and CAE according to the patients' choice between June 2013 and June 2016. All patients were thoroughly examined preoperatively and at 1, 3, 6, and 12 months after the operation, and the clinical results and the quality of life were evaluated. Read More

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http://dx.doi.org/10.1016/j.jvsv.2018.10.019DOI Listing
January 2019
5 Reads

Treatment of Lower Limbs Telangiectasias with Nd: Yag Laser-Prospective Study on 446 Patients.

Curr Health Sci J 2018 Jul-Sep;44(3):235-242. Epub 2018 Jul 15.

Medical Center Dr. Ianosi, Department of Internal Medicine, University of Medicine and Pharmacy of Craiova, Romania.

In the last two decades Nd: YAG laser has become a standard of treatment of telangiectasias of the lower limbs in CEAP stage of chronic venous insufficiency. This paper shows the results of a two years study period of telangiectasias of lower limbs with Nd: YAG laser conducted in a specialised centre in this type of procedures. The study group consisted of 446 patients (21 males and 425 females) with telangiectasias (CEAP) on the lower limbs between January 2016-December 2017. Read More

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http://dx.doi.org/10.12865/CHSJ.44.03.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311228PMC

Catastrophic antiphospholipid syndrome causing ST-segment elevation myocardial infarction with non-obstructive coronary arteries.

BMJ Case Rep 2019 Jan 10;12(1). Epub 2019 Jan 10.

Cardiology, West Suffolk NHS Foundation Trust, Bury Saint Edmunds, UK.

A 51-year-old woman with known primary antiphospholipid syndrome presented with a 4-day history of chest and abdominal pain, inferior ST-segment elevation on a 12-lead ECG and a subtherapeutic international normalised ratio. In view of a significantly raised high-sensitivity troponin I assay, inferior wall hypokinesis on transthoracic echocardiography and despite unobstructed epicardial vessels on emergency coronary angiography, a diagnosis of myocardial infarction was made. Furthermore, the patient also developed both bilateral adrenal haemorrhages leading to acute adrenal insufficiency and microvascular thrombotic renal disease concurrently. Read More

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http://dx.doi.org/10.1136/bcr-2018-225495DOI Listing
January 2019
2 Reads

Association of Serum 25-Hydroxyvitamin D Concentrations With Glucose Profiles in Male Collegiate Football Athletes.

Int J Sport Nutr Exerc Metab 2019 Jan 11:1-23. Epub 2019 Jan 11.

5 Faculty of Sport Sciences, Waseda University, Tokorozawa, Saitama, Japan.

Low serum 25-hydroxyvitamin D [25(OH)D] concentrations are associated with high risk of insulin resistance and type 2 diabetes mellitus (T2DM) in adults. However, it is unknown whether this is the case in American collegiate football and rugby athletes. This study investigated the associations between serum 25(OH)D concentrations and glucose profiles in male collegiate football athletes. Read More

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https://journals.humankinetics.com/doi/10.1123/ijsnem.2018-0
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http://dx.doi.org/10.1123/ijsnem.2018-0225DOI Listing
January 2019
5 Reads

Evaluation of Arterial Stiffness Using Pulse Wave Velocity and Augmentation Index in Patients with Chronic Venous Insufficiency.

Int J Vasc Med 2018 2;2018:5437678. Epub 2018 Dec 2.

Karaman State Hospital, Department of Cardiology, 70100 Karaman, Turkey.

Background And Objectives: Chronic venous insufficiency (CVI) is a common pathology of the circulatory system and is associated with a high morbidity for the patients and causes high costs for the healthcare systems. Arterial stiffness has been shown to be a predictor of cardiovascular events and mortality. The relationship between CVI and arterial stiffness using pulse wave velocity (PWV) and augmentation index (Aix) was evaluated in this study. Read More

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http://dx.doi.org/10.1155/2018/5437678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304525PMC
December 2018
2 Reads

Predictors of Chronic Thromboembolic Pulmonary Hypertension.

Kardiologiia 2018 Dec 25;58(12):60-65. Epub 2018 Dec 25.

Pirogov Russian National Research Medical University (RNRMU).

Purpose: to elucidate predictors of development of chronic thromboembolic pulmonary hypertension (CTEPH) after acute pulmonary artery thromboembolism (PTE).

Material And Methods: We included in this study 210 patients hospitalized with diagnosis of submassive and massive PTE from 2013 to 2017. In 1 to 3 years after initial hospitalization these patients were invited for control examination. Read More

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http://dx.doi.org/10.18087/cardio.2018.12.10206DOI Listing
December 2018
3 Reads

Prospective study of cryopreserved placental tissue wound matrix in the management of chronic venous leg ulcers.

J Vasc Surg Venous Lymphat Disord 2019 Jan 6. Epub 2019 Jan 6.

Division of Vascular Surgery, Department of Surgery, University of Maryland School of Medicine and Baltimore Veterans Administration Medical Center, Baltimore, Md. Electronic address:

Objective: Chronic venous leg ulcers (VLUs) affect up to 2% of the general population, resulting in a significant socioeconomic burden. Placental tissue that contains mesenchymal stem cells and active growth factors has been shown to be beneficial in healing of chronic wounds. We compared the efficacy of a human viable wound matrix (hVWM) of cryopreserved placental tissue for the treatment of refractory VLUs with standard therapy. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S2213333X183042
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http://dx.doi.org/10.1016/j.jvsv.2018.09.016DOI Listing
January 2019
5 Reads

[Drug-Based Therapy of Varicose Veins from the Perspective of Experimental Models].

Praxis (Bern 1994) 2019 Jan;108(1):31-36

1 Institut für Physiologie und Pathophysiologie, Abteilung Herz- und Kreislaufphysiologie, Universität Heidelberg, Deutschland.

Drug-Based Therapy of Varicose Veins from the Perspective of Experimental Models Abstract. Varicose remodeling of the venous wall primarily occurs in the lower extremities and is often associated with venous insufficiency. Although a large part of the western population shows various degrees of varicosis, little is known about the mechanisms driving their formation. Read More

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http://dx.doi.org/10.1024/1661-8157/a003147DOI Listing
January 2019
1 Read

Effects of compression therapy and venous surgery on tissue oxygenation in chronic venous disease.

Phlebology 2019 Jan 7:268355518822582. Epub 2019 Jan 7.

Department of Vascular Surgery, Waikato Hospital, Hamilton, New Zealand.

Objectives: This study aimed to determine if compression therapy or surgical intervention improves tissue oxygenation in chronic venous disease.

Method: Thirty lower limbs with chronic venous disease were placed into three groups, being compression, open surgical and endovenous ablation. Tissue oxygenation was assessed using a hyperspectral transcutaneous oxygen measurement system. Read More

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http://dx.doi.org/10.1177/0268355518822582DOI Listing
January 2019
3 Reads

A Case Review of Wound Bed Preparation in an Infected Venous Leg Ulcer Utilizing Novel Reticulated Open Cell Foam Dressing with Through Holes during Negative Pressure Wound Therapy with Instillation.

Cureus 2018 Oct 27;10(10):e3504. Epub 2018 Oct 27.

Plastic Surgery, Reading Hospital, Wyomissing, USA.

Chronic venous insufficiency (CVI) and venous leg ulcers (VLUs) have major financial implications for patients and healthcare professionals. VLUs, in particular, require significant care, can be slow to heal, and have a high rate of recurrence. These factors combine to make VLUs a major burden on the healthcare system. Read More

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http://dx.doi.org/10.7759/cureus.3504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314798PMC
October 2018
3 Reads

Successful replantation of an amputated helical rim with microvascular anastomosis.

Arch Craniofac Surg 2018 Dec 27;19(4):304-308. Epub 2018 Dec 27.

Department of Plastic and Reconstructive Surgery, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu, Korea.

Replantation using microvascular anastomosis is considered to be the optimal method in treating the amputated ear in terms of resulting color, texture, and shape. Only a few cases of ear replantation have been reported because it is anatomically difficult to identify suitable vessels for anastomosis. We successfully replanted the amputated helical rim of the ear using single arterial anastomosis. Read More

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http://dx.doi.org/10.7181/acfs.2018.02173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325333PMC
December 2018
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A pilot study of venous flow augmentation using a novel mechanical graded intermittent sequential compression device for venous insufficiency.

J Vasc Surg Venous Lymphat Disord 2019 Jan 3. Epub 2019 Jan 3.

Fogarty Institute for Innovation, Mountain View, Calif; Radial Medical, Inc, Mountain View, Calif.

Background: Guidelines as well as multiple RTCs support the use of intermittent pneumatic compression (IPC) for the treatment of venous leg ulcers when conservative measures fail. Unfortunately, the clinical usefulness of IPC is significantly limited by the physical limitations of pneumatic motors, which leads to bulky devices with slow inflation cycles, uncomfortable sleeves, lack of patient mobility, and ultimately poor patient compliance with therapy. A novel mechanical device for lower leg graded intermittent sequential compression was designed to address these limitations of IPC therapy for venous leg ulcer treatment by providing rapid compression cycles in a truly wearable device that offers the additional benefit of monitoring compression dose and patient compliance. Read More

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http://dx.doi.org/10.1016/j.jvsv.2018.10.018DOI Listing
January 2019
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Exploration of robotic-assisted surgical techniques in vascular surgery.

J Robot Surg 2019 Jan 4. Epub 2019 Jan 4.

Department of Vascular and Endovascular Surgery, University of Michigan, Ann Arbor, MI, 48109, USA.

Robotic-assisted surgical approaches for vascular surgery are feasible regarding minimally invasive exposure, dissection, ligation and skeletonization for varicose vein ligation, anterior spine exposure, femoral-popliteal bypass, femoral vein harvest and aortic aneurysm repair. The authors performed a cadaveric exploration to demonstrate proof of concept and feasibility for a robotic-assisted approached. Surgeon autonomy over endoscopic vision, robotic instrumentation and retraction were noted as key benefits over existing open vascular approaches. Read More

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http://dx.doi.org/10.1007/s11701-018-00917-8DOI Listing
January 2019
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Protocol for a longitudinal cohort study: determination of risk factors for the development of first venous leg ulcer in people with chronic venous insufficiency, the VEINS (venous insufficiency in South Florida) cohort.

BMJ Open 2019 Jan 3;9(1):e023313. Epub 2019 Jan 3.

Dermatology and Cutaneous Surgery, University of Miami School of Medicine, Miami, Florida, USA.

Introduction: Chronic venous insufficiency (CVI) affects up to one-third of the adult population yet venous leg ulcers (VLU), a significant complication of CVI, only affect 1%-2% of adults in the USA. Why some develop VLU and others do not is unclear. VLU have a significant impact on quality of life and are extremely costly and difficult to treat. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-023313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326300PMC
January 2019
3 Reads

Chronic non-healing wounds in geriatrics.

Vnitr Lek 2018 ;64(11):1098-1104

Chronic non-healing wounds represent a frequent comorbidity among geriatric patients. Non-healing wounds increase patients morbidity and mortality and significantly decrease their quality of life. Prognosis of these wounds depends on etiology, overall health condition of the patient and also on the proper treatment. Read More

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January 2018
2 Reads

A Case of Successful Iliofemoral Vein Stenting from Great Saphenous Vein Access.

Heart Surg Forum 2018 Nov 14;21(6):E472-E475. Epub 2018 Nov 14.

Department of Cardiology, Daegu Catholic University Medical Center, Daegu, Republic of Korea.

Chronic venous disease is strongly associated with morbidity and leads to considerable medical costs. Therefore, its clinical significance is very important. Currently, iliac vein stenting is the first treatment option for chronic venous disease due to iliac vein obstruction. Read More

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http://dx.doi.org/10.1532/hsf.2087DOI Listing
November 2018
1 Read

Venoprotective drugs in pigmented purpuric dermatoses: A case report.

J Cosmet Dermatol 2019 Jan 1. Epub 2019 Jan 1.

Dr Ram Manohar Lohia Hospital and Post Graduate Institute of Medical Education and Research, New Delhi, India.

Pigmented purpuric dermatoses (PPD) or capillaritis represent a benign condition, presenting with extravasation of erythrocytes in the skin and prominent hemosiderin deposition. The eruption runs a chronic relapsing course and is resistant to therapy. Capillary fragility, cellular immunity, and microvascular inflammation play important roles in the pathogenesis of PPD. Read More

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http://dx.doi.org/10.1111/jocd.12850DOI Listing
January 2019
3 Reads

LivRelief varicose veins cream in the treatment of chronic venous insufficiency of the lower limbs: A 6-week single arm pilot study.

PLoS One 2018 31;13(12):e0208954. Epub 2018 Dec 31.

Department of Medical Science, McMaster University, Hamilton, Ontario, Canada.

Background: Chronic Venous Disease is characterized by morphological abnormalities of the venous system. Affected limbs are classified in increasing clinical severity with the Clinical Etiological Anatomical and Pathological system from C0 to C6. Limbs assessed at C3 through C6 meet the criteria of Chronic Venous Insufficiency. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0208954PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312404PMC
December 2018
1 Read

Mechanochemical ablation for the treatment of superficial venous incompetence: A cohort study of a single centre's early experience.

Phlebology 2018 Dec 30:268355518818339. Epub 2018 Dec 30.

Hull York Medical School, Academic Vascular Surgical Unit, Alderson House, Hull Royal Infirmary, Hull, UK.

Background: Mechanochemical ablation is an innovative non-thermal method of treating symptomatic axial superficial venous incompetence. This is a single-centre cohort study aiming to investigate the technical efficacy and clinical effectiveness at one year.

Methods: Patients with primary, unilateral, symptomatic axial incompetence were offered treatment with mechanochemical ablation using ClariVein® with 1. Read More

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http://dx.doi.org/10.1177/0268355518818339DOI Listing
December 2018
3 Reads

The efficacy and safety of direct oral anticoagulants in patients with chronic renal insufficiency: A review of the literature.

Eur J Haematol 2018 Dec 28. Epub 2018 Dec 28.

The Division of Hematology & Oncology, School of Medicine, Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon.

Direct oral anticoagulants (DOACs) have been shown to be superior to vitamin K antagonists (VKAs) in regards to safety and efficacy in numerous clinical trials and are now the preferred oral anticoagulant by multiple professional societies. However, patients with significant levels of organ dysfunction were excluded from all major clinical trials, leaving the clinical benefit in these subsets uncertain. Patients with chronic kidney disease (CKD) specifically often require anticoagulation for acute or long-term indications such as venous thromboembolism, atrial fibrillation, or mechanical heart valves. Read More

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http://dx.doi.org/10.1111/ejh.13208DOI Listing
December 2018
2 Reads