747 results match your criteria Vein of Galen Malformation


Occlusion of a mural type vein of Galen malformation in a 10-month-old boy with three Woven EndoBridge (WEB 17) and two coils.

BMJ Case Rep 2019 Apr 14;12(4). Epub 2019 Apr 14.

Department of Diagnostic and Interventional Radiology and Neuroradiology, Universitätsklinikum Augsburg, Augsburg, Germany.

We report the case of a 10-month-old boy with an enlarged head circumference and severe motor developmental delay. MRI showed a vein of Galen malformation (VGAM) with a heavily dilated median prosencephalic vein. Digital subtraction angiography confirmed a mural type VGAM with three feeding arteries arising from the posterior cerebral arteries. Read More

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http://dx.doi.org/10.1136/bcr-2018-014652DOI Listing
April 2019
1 Read

Pial arteriovenous fistula with multiple venous aneurysms resembling a vein of Galen aneurysmal malformation.

World Neurosurg 2019 Apr 11. Epub 2019 Apr 11.

Division of Vascular and Endovascular Neurosurgery, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran; Neuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address:

Pial arteriovenous fistulas (pAVFs) are abnormal vascular connections between arteries and the cranial venous system on the surface of the brain in the pia mater. Unlike vein of Galen aneurysmal malformations (VGAM), they lack a true vascular nidus, and may only indirectly involve the vein of Galen. We describe a case of a pAVF with a presentation resembling a VGAM and discuss the importance of considering a pAVF as a possible differential diagnosis to a VGAM when the vein of Galen is dilated. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.04.061DOI Listing
April 2019
1 Read

Serial Quantitative and Qualitative Measurements of Flow in Vein of Galen Malformations Using 4D Flow MRI (PC-VIPR): Case Report.

World Neurosurg 2019 Mar 5. Epub 2019 Mar 5.

Department of Neurological Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA; Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.wneu.2019.02.131DOI Listing

An unusual cause of cardiac failure in a neonate.

Arch Pediatr 2019 Apr 1;26(3):176-178. Epub 2019 Mar 1.

Service de réanimation néonatale, CHU Hassan II-Fès, université Sidi Mohamed Ben Abdellah, 30000 Fès, Morocco.

We report the case of a newborn admitted with signs of congestive cardiac failure with prominent and pulsatile cervical veins. Echocardiography showed a structurally normal heart, right-to-left ductal flow, and reversed diastolic flow in the proximal descending aorta. A computed-tomography scan of the head showed a vein of Galen arteriovenous malformation. Read More

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http://dx.doi.org/10.1016/j.arcped.2019.02.004DOI Listing
April 2019
6 Reads

EphrinB2-EphB4-RASA1 Signaling in Human Cerebrovascular Development and Disease.

Trends Mol Med 2019 Apr 25;25(4):265-286. Epub 2019 Feb 25.

Department of Neurosurgery, Yale School of Medicine, New Haven CT, USA; Department of Pediatrics, Yale School of Medicine, New Haven CT, USA; Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven CT, USA. Electronic address:

Recent whole exome sequencing studies in humans have provided novel insight into the importance of the ephrinB2-EphB4-RASA1 signaling axis in cerebrovascular development, corroborating and extending previous work in model systems. Here, we aim to review the human cerebrovascular phenotypes associated with ephrinB2-EphB4-RASA1 mutations, including those recently discovered in Vein of Galen malformation: the most common and severe brain arteriovenous malformation in neonates. We will also discuss emerging paradigms of the molecular and cellular pathophysiology of disease-causing ephrinB2-EphB4-RASA1 mutations, including the potential role of somatic mosaicism. Read More

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http://dx.doi.org/10.1016/j.molmed.2019.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456402PMC
April 2019
3 Reads

Embolization of cerebral arteriovenous shunts in infants weighing less than 5 kg.

J Neurosurg Pediatr 2019 Feb 22:1-9. Epub 2019 Feb 22.

1Neuroradiologie Interventionnelle, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.

OBJECTIVEEndovascular treatment in children, especially neonates, can be more challenging than analogous procedures in adults. This study aimed to describe the clinical and radiological findings, type and timing of endovascular treatment, and early outcomes in children who present with neurovascular malformations, who are treated with embolization, and who weigh less than 5 kg.METHODSThe authors carried out a retrospective review of all consecutively treated children weighing less than 5 kg with neurovascular arteriovenous malformations (AVMs) at a single institution over a 10-year period. Read More

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http://dx.doi.org/10.3171/2018.11.PEDS1865DOI Listing
February 2019
2 Reads

A Severe Case of Aneurysmal Malformation of the Vein of Galen, Cardiac Failure and Intrauterine Fetal Death.

Curr Health Sci J 2018 Jan-Mar;44(1):76-79. Epub 2018 Mar 29.

Department of Obstetrics and Gynecology, University of Medicine and Pharmacy of Craiova, Romania.

Aneurism of the vein of Galen is a rare congenital anomaly, where complex arteriovenous malformation are identified between multiple choroidal arteries and the median prosencephalic vein of Markowski, which is a precursor of the vein of Galen, with subsequent aneurysmal enlargement of the respective arteriovenous system. The congenital malformation develops during week 6 to 11 of fetal development. Infants often die from high-output congestive heart failure. Read More

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http://dx.doi.org/10.12865/CHSJ.44.01.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295180PMC
March 2018
12 Reads

Distal microcatheter placement using the Asahi Chikai 0.008-inch micro-guidewire for liquid embolic material delivery: A technical note.

World Neurosurg 2019 Jan 4. Epub 2019 Jan 4.

Department of Neurosurgery, Icahn School of Medicine ,Mount Sinai Health Care System, New York, New York,USA.

Introduction: Management of vascular malformations requires microcatheter manipulation through distal tortuous arterial feeders less than a millimetre in diameter, to permit safe and effective embolization at the fistula or nidus location. The Asahi Chikai 0.008 inch micro-guidewire recently introduced in the United States was used to evaluate microcatheter torque, support and safety in distal microcatheter navigation. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.12.132DOI Listing
January 2019
1 Read

Mutations in Chromatin Modifier and Ephrin Signaling Genes in Vein of Galen Malformation.

Neuron 2019 Feb 18;101(3):429-443.e4. Epub 2018 Dec 18.

Department of Neurosurgery, Yale School of Medicine, New Haven, CT, USA; Department of Pediatrics, Yale School of Medicine, New Haven, CT, USA; Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT, USA. Electronic address:

Normal vascular development includes the formation and specification of arteries, veins, and intervening capillaries. Vein of Galen malformations (VOGMs) are among the most common and severe neonatal brain arterio-venous malformations, shunting arterial blood into the brain's deep venous system through aberrant direct connections. Exome sequencing of 55 VOGM probands, including 52 parent-offspring trios, revealed enrichment of rare damaging de novo mutations in chromatin modifier genes that play essential roles in brain and vascular development. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08966273183105
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http://dx.doi.org/10.1016/j.neuron.2018.11.041DOI Listing
February 2019
30 Reads

Pediatric encephalic ultrasonography: the essentials.

J Ultrasound 2018 Dec 14. Epub 2018 Dec 14.

Radiology Department, "Santobono-Pausilipon" Children Hospital, Naples, Italy.

Nowadays, cranial ultrasonography (US) of the newborn represents the first imaging method in brain damage study and its possible outcomes. This exam is performed using the natural fontanelles, especially the anterior one. It is fast, non-invasive and does not produce any side effect. Read More

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http://dx.doi.org/10.1007/s40477-018-0349-7DOI Listing
December 2018
4 Reads

Commentary: Vein of Galen Malformations: The Texas Children's Hospital Experience in the Modern Endovascular Era.

Oper Neurosurg (Hagerstown) 2018 Dec 14. Epub 2018 Dec 14.

Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, New York.

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http://dx.doi.org/10.1093/ons/opy374DOI Listing
December 2018

Rapid cardiac ventricular pacing to facilitate embolization of vein of Galen malformations: technical note.

J Neurosurg Pediatr 2018 Oct;23(1):86-91

1Division of Neurosurgery, Department of Clinical Neurosciences, University of Calgary.

In BriefBabies born with life-threatening brain blood-vessel malformations can be helped with new heart pacemaker technology to temporarily stop the flow of blood in their bodies during surgery, for inducing hypotension to aid in controlled embolization. Read More

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http://dx.doi.org/10.3171/2018.7.PEDS1852DOI Listing
October 2018
10 Reads
1.370 Impact Factor

[Vein of Galen aneurysmal malformation in a Neonate: a case report].

Mali Med 2018 ;33(2):23-25

Centre National Hospitalier Universitaire Hubert Koutoukou Maga de Cotonou, Bénin.

The aneurysm of the Galen vein is a rare and complex congenital intracerabral vascular malformation. We report a case suspected by the obstetric ultrasound in the third trimester and confirmed by the transfontanellar Doppler ultrasound and brain CT-Scan in the asymptomatic 11-day old baby born at term. Read More

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January 2018

Fetal stroke and cerebrovascular disease: Advances in understanding from lenticulostriate and venous imaging, alloimmune thrombocytopaenia and monochorionic twins.

Eur J Paediatr Neurol 2018 Nov 11;22(6):989-1005. Epub 2018 Sep 11.

Departments of Child Health, Obstetrics and Gynaecology and Radiology, University Hospital Southampton, United Kingdom; Clinical and Experimental Sciences, University of Southampton, United Kingdom.

Fetal stroke is an important cause of cerebral palsy but is difficult to diagnose unless imaging is undertaken in pregnancies at risk because of known maternal or fetal disorders. Fetal ultrasound or magnetic resonance imaging may show haemorrhage or ischaemic lesions including multicystic encephalomalacia and focal porencephaly. Serial imaging has shown the development of malformations including schizencephaly and polymicrogyra after ischaemic and haemorrhagic stroke. Read More

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http://dx.doi.org/10.1016/j.ejpn.2018.08.008DOI Listing
November 2018
15 Reads

Susceptibility weighted imaging in infants with staged embolization of vein of Galen aneurysmal malformations.

J Neuroradiol 2019 May 10;46(3):214-221. Epub 2018 Nov 10.

Division of Pediatric Radiology and Pediatric Neuroradiology, Russell H. Morgan Department of Radiology and Radiological Science, Johns-Hopkins University School of Medicine, Baltimore, Maryland, USA. Electronic address:

Background And Purpose: The vein of Galen aneurysmal malformation (VGAM) is a rare congenital vascular malformation with a higher morbidity and mortality, especially in neonates. Ultrasound, CT and MR are usually used in diagnosis and treatment monitoring of these disorders. In this current study, we aim to examine utility of SWI in evaluation of treatment response in infants with VGAM. Read More

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http://dx.doi.org/10.1016/j.neurad.2018.09.009DOI Listing
May 2019
2 Reads

Pediatric Congenital Cerebrovascular Anomalies.

J Neuroimaging 2019 Mar 31;29(2):165-181. Epub 2018 Oct 31.

Department of Interventional Radiology, Sanford Aberdeen Clinic, Aberdeen, SD.

Congenital cerebrovascular anomalies in the pediatric age group are myriad with diverse etiologies. The purpose of this paper is to provide an imaging overview of congenital vascular malformations and vascular tumors, as these conditions are varied and the characteristic vascular abnormality may even suggest the underlying systemic condition in helping to guide further management. For example, the identification of an arterial anomaly such as agenesis/hypoplasia/duplication may warrant further evaluation for an associated syndrome. Read More

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http://doi.wiley.com/10.1111/jon.12575
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http://dx.doi.org/10.1111/jon.12575DOI Listing
March 2019
25 Reads

Right superior caval vein to the left atrium in a child with vein of Galen malformation.

Echocardiography 2018 11 16;35(11):1868-1871. Epub 2018 Oct 16.

Department of Cardiology, All India Institute of Medical Sciences, New Delhi, India.

Vein of Galen malformation (VGM) is a rare intracranial vascular malformation. High output heart failure is common in infancy and is characterized by dilatation of all the cardiac chambers. We report an unusual case of VGM in a 3-month-old infant without dilatation of the right-sided cardiac chambers. Read More

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http://doi.wiley.com/10.1111/echo.14165
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http://dx.doi.org/10.1111/echo.14165DOI Listing
November 2018
17 Reads

Endovascular management of vein of Galen aneurysmal malformation in a neonate.

Ann Pediatr Cardiol 2018 Sep-Dec;11(3):304-307

Department of Neuroimaging and Interventional Neuroradiology, CN Centre, All India Institute of Medical Sciences, New Delhi, India.

A term baby presented on the 7 day of life in cardiogenic shock due to vein of Galen aneurysmal malformation. A successful embolization of the malformation was performed through transarterial route on day 12 of life after a period of initial stabilization. Read More

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http://dx.doi.org/10.4103/apc.APC_33_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146857PMC
October 2018
6 Reads

Aneurysmal dilation of the vein of Galen and straight sinus with resultant obstructive hydrocephalus.

BMJ Case Rep 2018 Sep 27;2018. Epub 2018 Sep 27.

Hematology Oncology, University of Arizona Medical Center, Tucson, Arizona, USA.

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http://dx.doi.org/10.1136/bcr-2018-226742DOI Listing
September 2018
1 Read

A rare case of spontaneous thrombosis of vein of Galen malformation in a young adult diagnosed on magnetic resonance imaging and digital subtraction angiography.

Neurol India 2018 Sep-Oct;66(5):1505-1506

Department of Neurosciences, Medanta, The Medicity, Gurgaon, Haryana, India.

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http://dx.doi.org/10.4103/0028-3886.241344DOI Listing
September 2018
3 Reads
1.084 Impact Factor

Vein of Galen varix associated with straight sinus arachnoid granulation.

Acta Neurol Belg 2018 Aug 29. Epub 2018 Aug 29.

Neuroradiology Unit, Department of Neuroscience, University Hospitals of Modena, Via P. Giardini, 1355, Modena, Italy.

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http://dx.doi.org/10.1007/s13760-018-1010-0DOI Listing
August 2018
2 Reads

Cross-sectional study of a United Kingdom cohort of neonatal vein of galen malformation.

Ann Neurol 2018 Oct 4;84(4):547-555. Epub 2018 Oct 4.

Developmental Neurosciences Programme, UCL Great Ormond Street Institute of Child Health, London.

Objective: Describe the course and outcomes in a UK national cohort of neonates with vein of Galen malformation identified before 28 days of life.

Methods: Neonates with angiographically confirmed vein of Galen malformation presenting to 1 of 2 UK treatment centers (2006-2016) were included; those surviving were invited to participate in neurocognitive assessment. Results in each domain were dichotomized into "good" and "poor" categories. Read More

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http://doi.wiley.com/10.1002/ana.25316
Publisher Site
http://dx.doi.org/10.1002/ana.25316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221157PMC
October 2018
14 Reads

Cerebral Arteriovenous Malformation Detected by Newborn Congenital Heart Disease Screen with Echocardiography.

CASE (Phila) 2017 Dec 19;1(6):242-244. Epub 2017 Oct 19.

Department of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1016/j.case.2017.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058347PMC
December 2017
3 Reads

Nationwide survey of pediatric intracranial arteriovenous shunts in Japan: Japanese Pediatric Arteriovenous Shunts Study (JPAS).

J Neurosurg Pediatr 2018 Nov;22(5):550-558

Departments of4Neuroendovascular Therapy and.

The authors performed a nationwide study in Japan to evaluate the annual detected rate of pediatric intracranial arteriovenous (AV) shunts such as brain AV malformations (BAVMs), pial AV fistulas (PAVFs), vein of Galen aneurysmal malformations (VGAMs), and dural AV fistulas (DAVFs). These rates were revealed for the first time and showed that VGAM, DAVF, and PAVF were relatively common but that BAVMs were extremely rare in neonates and infants. Read More

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http://dx.doi.org/10.3171/2018.5.PEDS18123DOI Listing
November 2018
1 Read

Clinical Outcome of Nonfistulous Cerebral Varices: the Analysis of 39 Lesions.

J Korean Neurosurg Soc 2018 Jul 1;61(4):485-493. Epub 2018 Jul 1.

Department of Neurosurgery, Seoul National University Hospital, Seoul, Korea.

Objective: Cerebral varices (CVs) without an arteriovenous shunt, so called nonfistulous CVs, are very rare, and their etiology and natural course are not well understood. The aim of this study is to evaluate the clinical outcomes of nonfistulous CVs by the analysis of 39 cases.

Methods: From 2000 to 2015, 22 patients with 39 nonfistulous CVs (≥5 mm) were found by searching the medical and radiologic records of our institute. Read More

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http://dx.doi.org/10.3340/jkns.2018.0089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046564PMC
July 2018
5 Reads

Outcome of Neonates with Vein of Galen Malformation Presenting with Severe Heart Failure: A Case Series.

Am J Perinatol 2019 Jan 10;36(2):169-175. Epub 2018 Jul 10.

Paediatric Intensive Care Unit, Catholic University "A. Gemelli" Hospital, Rome, Italy.

Background:  Neonatal presentation of vein of Galen aneurysmal malformations (VGAMs) complicated by cardiac failure and pulmonary hypertension is frequently associated with a poor prognosis. Interventional neuroradiology with embolization can offer a chance for survival, although neurological damage can represent a limitation.

Objective:  This article determines if aggressive intensive care and drug management of cardiac failure before urgent embolization can influence morbidity and mortality. Read More

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http://dx.doi.org/10.1055/s-0038-1666813DOI Listing
January 2019
5 Reads

[Vein of Galen aneurysmal malformation. A case series].

An Pediatr (Barc) 2018 Jul 5. Epub 2018 Jul 5.

Servicio de Neonatología, Hospital Universitari i Politècnic La Fe, Valencia, España.

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http://dx.doi.org/10.1016/j.anpedi.2018.05.018DOI Listing
July 2018
2 Reads

A review of extraaxial developmental venous anomalies of the brain involving dural venous flow or sinuses: persistent embryonic sinuses, sinus pericranii, venous varices or aneurysmal malformations, and enlarged emissary veins.

Neurosurg Focus 2018 Jul;45(1):E9

3Department of Medical Imaging, University of Arizona College of Medicine, Tucson, Arizona.

This paper is a narrative review of extraaxial developmental venous anomalies (eDVAs) of the brain involving dural venous flow or sinuses: persistent embryonic sinuses, sinus pericranii, enlarged emissary veins, and venous varices or aneurysmal malformations. The article highlights the natural history, anatomy, embryology, imaging, clinical implications, and neurosurgical significance of these lesions, which the authors believe represent a continuum, with different entities characterized by distinct embryopathologic features. The indications and surgical management options are discussed for these individual intracranial pathologies with relevant illustrations, and a novel classification is proposed for persistent falcine sinus (PFS). Read More

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http://dx.doi.org/10.3171/2018.5.FOCUS18107DOI Listing
July 2018
16 Reads

Microsurgical Management of Vascular Malformations of the Pineal Region.

World Neurosurg 2018 Sep 23;117:e669-e678. Epub 2018 Jun 23.

Department of Neurosurgery, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.

Background: Vascular pineal malformations are rare and technically demanding lesions. Because the locations of these lesions, endovascular techniques and radiosurgery have been increasingly used in the recent decades to accomplish safe occlusion. Nevertheless, microsurgical treatment may be required sometimes. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.06.110DOI Listing
September 2018
2.420 Impact Factor

Isolated right superior vena cava draining into the left atrium in a child with vein of Galen aneurysmal malformation-case report.

J Cardiothorac Surg 2018 Jun 13;13(1):66. Epub 2018 Jun 13.

Department of Pediatric Cardiology, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia.

Background: Isolated right Superior Vena Cava drainage into the left atrium in the absence of other cardiac anomalies is an extremely rare condition. The vein of Galen aneurysmal malformation is a congenital vascular malformation. It comprises 1% of all pediatric congenital anomalies. Read More

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http://dx.doi.org/10.1186/s13019-018-0758-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998586PMC
June 2018
3 Reads
1.018 Impact Factor

Vein of Galen Malformation Thrombosis by Single-Stage, 2-Coil Embolization.

World Neurosurg 2018 Aug 1;116:296-298. Epub 2018 Jun 1.

Department of Neurosurgery, Augusta University, Augusta, Georgia, USA.

Advances in endovascular embolization have improved morbidity and mortality among patients with vein of Galen malformations (VoGMs). The patient presented at 3 months of age with increased head circumference and a bruit over his anterior fontanelle. Diagnostic cerebral angiography confirmed the presence of a large mural-type VoGM. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.05.184DOI Listing
August 2018
3 Reads

Vein of Galen Aneurysmal Malformation: Advances in Management and Endovascular treatment.

Neurosurgery 2019 Feb;84(2):469-478

Department of Neurosurgery, Icahn School of Medicine at Mount Sinai Hospital, New York, New York.

Background: Vein of Galen aneurysmal malformation (VGAM) is a rare congenital vascular malformation representing <1% of all arteriovenous malformations. The knowledge and strategies in the management are constantly evolving.

Objective: To review our series of postneonatal VGAM patients treated over 11-yr period. Read More

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http://dx.doi.org/10.1093/neuros/nyy100DOI Listing
February 2019
22 Reads

Anatomy of the deep venous system in vein of Galen malformation and its changes after endovascular treatment depicted by magnetic resonance venography.

J Neurointerv Surg 2019 Jan 24;11(1):84-89. Epub 2018 May 24.

Department of Diagnostic and Interventional Neuroradiology, Hannover Medical School, Hannover, Germany.

Background And Purpose: It is classically thought that the internal cerebral veins (ICV) do not communicate with the venous pouch of vein of Galen malformations (VGM). We report on the anatomy of the deep venous system in VGM with special emphasis on the drainage of the ICV and possible changes after endovascular treatment.

Materials And Methods: We retrospectively analyzed DSA and 2D time-of-flight MR venograms of 55 children with VGM. Read More

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http://dx.doi.org/10.1136/neurintsurg-2018-013789DOI Listing
January 2019
16 Reads

Repair of Sinus Venosus Defect and Anomalous Pulmonary Veins Associated With Vein of Galen Malformation.

World J Pediatr Congenit Heart Surg 2018 Jan 1:2150135118769325. Epub 2018 Jan 1.

1 Division of Pediatric Cardiology, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.

Sinus venosus defect (SVD) is a deficiency in the sinus venosus portion of the atrium, often associated with partial anomalous pulmonary venous connections. In patients with vein of Galen malformation (VGAM), SVD provides a unique challenge with respect to embolization treatment. In our case, the child had percutaneous device closure of the SVD prior to VGAM embolization. Read More

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http://dx.doi.org/10.1177/2150135118769325DOI Listing
January 2018
5 Reads

Choroidal Type of Vein of Galen Aneurysmal Malformation in Adult Patient with Unusual Presentation of Orthostatic Headache.

Asian J Neurosurg 2018 Apr-Jun;13(2):418-420

Department of Neurosurgery, SMS Medical College, Jaipur, Rajasthan, India.

Vein of Galen aneurysmal malformations (VGAMs) are rare vascular malformations occurring commonly in the pediatric age group. They comprise only 1% of all intracranial vascular malformations, but in pediatric population, they represent 30% of all intracranial vascular malformations. They are of two types-mural and choroidal. Read More

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http://dx.doi.org/10.4103/1793-5482.228542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898119PMC
April 2018
6 Reads

Imaging Characteristics of Dural Arteriovenous Fistulas Involving the Vein of Galen: A Comprehensive Review.

Cureus 2018 Feb 11;10(2):e2180. Epub 2018 Feb 11.

Neurosurgery, Seattle Science Foundation.

Vein of Galen aneurysmal malformation (VGAM) is a rare angiopathy, which most commonly presents in infancy. Although very rare, it is associated with high morbidity and mortality rates. In order to minimize such morbid rates, a prompt diagnosis followed by a timely initiation of management is crucial. Read More

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http://dx.doi.org/10.7759/cureus.2180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896872PMC
February 2018
4 Reads

Estimating the Global Incidence of Aneurysmal Subarachnoid Hemorrhage: A Systematic Review for Central Nervous System Vascular Lesions and Meta-Analysis of Ruptured Aneurysms.

World Neurosurg 2018 Jul 9;115:430-447.e7. Epub 2018 Apr 9.

Department of Global Health and Social Medicine, Harvard Medical School, Global Neurosurgery Initiative, Program in Global Surgery and Social Change, Boston, Massachusetts, USA.

Introduction: There is increasing acknowledgement that surgical care is important in global health initiatives. In particular, neurosurgical care is as limited as 1 per 10 million people in parts of the world. We performed a systematic literature review to examine the worldwide incidence of central nervous system vascular lesions and a meta-analysis of aneurysmal subarachnoid hemorrhage (aSAH) to define the disease burden and inform neurosurgical global health efforts. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183071
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http://dx.doi.org/10.1016/j.wneu.2018.03.220DOI Listing
July 2018
12 Reads
2.420 Impact Factor

Dilated superior vena cava in fetal echocardiographic three-vessel view: what lies ahead?

Heart Asia 2018 29;10(1):e010998. Epub 2018 Mar 29.

Department of Cardiology, Manipal Hospital, Bangalore, Karnataka, India.

A 38-year-old woman, 37+3 weeker was incidentally detected to have fetal cardiomegaly during 36 weeks ultrasound and referred for fetal echocardiogram. Antenatal history and anomaly scan were normal. Fetal echocardiogram showed heart rate of 153/min, sinus rhythm, situs solitus, levocardia, dilated right atrium and ventricle with venoatrial, atrioventricular and ventriculoarterial concordances. Read More

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http://dx.doi.org/10.1136/heartasia-2018-010998DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890057PMC
March 2018
4 Reads

Discovery of a cause of vein of Galen malformations.

Authors:
James F Meschia

Brain 2018 Apr;141(4):936-938

Cerebrovascular Division, Department of Neurology, Mayo Clinic, Jacksonville, FL, USA.

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http://dx.doi.org/10.1093/brain/awy066DOI Listing
April 2018
3 Reads

Adjuvant Coil Assisted Glue Embolization of Vein of Galen Aneurysmal Malformation in Pediatric Patients.

Neurointervention 2018 Mar 2;13(1):41-47. Epub 2018 Mar 2.

Department of Radiology, Yonsei University College of Medicine, Seoul, Korea.

Purpose: Adjuvant coils may offer advantages in flow control during glue embolization of high flow vein of Galen aneurysmal malformation (VGAM) patients but involves specific issues such as feasibility, durability and coil mass effect. The purpose of this study is to assess the outcome of adjuvant coils in addition to transarterial glue embolization for treatment of these patients.

Materials And Methods: Five pediatric VGAM patients (age range; 11 weeks to 2 yrs 2 mos) with high flow fistulous angioarchitecture were treated with adjuvant coils 1) in the distal feeding artery and/or 2) in the vein of Galen followed by glue embolization of the shunt. Read More

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http://dx.doi.org/10.5469/neuroint.2018.13.1.41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847889PMC
March 2018
5 Reads

[Vein of Galen aneurysmal malformation].

Ceska Gynekol Winter 2018;83(1):37-39

Objective: A case report of the pregnancy complicated by the presence of vein of Galen aneurysmal malformation in fetus.

Design: The case report.

Setting: Department of Obstetrics and Gynaecology, Masaryks Hospital, Jilemnice; Obstetrics and Gynecology Clinic, University Hospital in Hradec Králové. Read More

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January 2019
4 Reads

Loss of function mutations in EPHB4 are responsible for vein of Galen aneurysmal malformation.

Brain 2018 Apr;141(4):979-988

Institut National de la Santé et de la Recherche Médicale (Inserm) UMR-1169 and University Paris Sud, Le Kremlin Bicêtre, 94276, France.

See Meschia (doi:10.1093/brain/awy066) for a scientific commentary on this article.Vein of Galen aneurysmal malformation is a congenital anomaly of the cerebral vasculature representing 30% of all paediatric vascular malformations. Read More

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http://dx.doi.org/10.1093/brain/awy020DOI Listing
April 2018
8 Reads

Vein of Galen malformation: optimizing the management of postneonatal presentations.

Authors:
Dan Meila

Dev Med Child Neurol 2018 04 14;60(4):340-341. Epub 2018 Feb 14.

Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1111/dmcn.13712DOI Listing
April 2018
1 Read

Non-enhanced MR imaging for preinterventional assessment of the angioarchitecture in vein of Galen malformations.

J Neurointerv Surg 2018 Oct 7;10(10):999-1004. Epub 2018 Feb 7.

Department of Diagnostic and Interventional Neuroradiology, Medical School Hannover, Hannover, Germany.

Background And Purpose: Endovascular treatment of vein of Galen malformations (VGMs) requires sufficient preceding MR imaging. Standardized, preinterventional, non-invasive imaging has not been established. Our study is the first to examine the role of a dedicated, standardized, non-invasive imaging protocol in the evaluation of VGM angioarchitecture by non-contrast MRI/MR angiography. Read More

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http://dx.doi.org/10.1136/neurintsurg-2017-013611DOI Listing
October 2018
74 Reads

Multimodality Management of Vein of Galen Malformations-An Institutional Experience.

World Neurosurg 2018 Apr 3;112:e837-e847. Epub 2018 Feb 3.

Department of Neurosurgery, Medical University of Vienna, Vienna, Austria; Department of Neurosurgery, Kepler Universitätsklinikum, Johannes Kepler University Linz, Linz, Austria.

Background: The vein of Galen aneurysmal malformation (VGM) is a rare intracranial arteriovenous fistula with a dramatic manifestation during infancy and 100% mortality without treatment. Therapeutic strategies for VGMs have changed over time as a result of advances in endovascular techniques. We present our experience and multimodality approach within the last 4 decades. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.01.172DOI Listing
April 2018
4 Reads

Adenosine-induced cardiac standstill for endovascular treatment of pediatric vein of Galen malformations.

J Neurosurg Pediatr 2018 04 26;21(4):380-383. Epub 2018 Jan 26.

Vein of Galen malformations are congenital high-flow vascular malformations that often present with heart failure, hydrocephalus, developmental delay, and intracranial hemorrhage. Because open surgical treatment is associated with high morbidity and mortality, endovascular embolization is increasingly becoming the preferred method of intervention. However, embolization of these lesions can be difficult because of their high-flow nature. Read More

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http://dx.doi.org/10.3171/2017.10.PEDS17488DOI Listing
April 2018
4 Reads

Presentation, course, and outcome of postneonatal presentations of vein of Galen malformation: a large, single-institution case series.

Dev Med Child Neurol 2018 04 23;60(4):424-429. Epub 2018 Jan 23.

Developmental Neurosciences, UCL Great Ormond Street Institute of Child Health, London, UK.

Aim: To describe presentation, clinical course, and outcome in postneonatal presentations of vein of Galen malformation (VGM).

Method: Children older than 28 days presenting with VGM (from 2006-2016) were included. Notes/scans were reviewed. Read More

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http://dx.doi.org/10.1111/dmcn.13676DOI Listing
April 2018
17 Reads

Human genetics and molecular mechanisms of vein of Galen malformation.

J Neurosurg Pediatr 2018 04 19;21(4):367-374. Epub 2018 Jan 19.

1Department of Neurosurgery.

Vein of Galen malformations (VOGMs) are rare developmental cerebrovascular lesions characterized by fistulas between the choroidal circulation and the median prosencephalic vein. Although the treatment of VOGMs has greatly benefited from advances in endovascular therapy, including technical innovation in interventional neuroradiology, many patients are recalcitrant to procedural intervention or lack accessibility to specialized care centers, highlighting the need for improved screening, diagnostics, and therapeutics. A fundamental obstacle to identifying novel targets is the limited understanding of VOGM molecular pathophysiology, including its human genetics, and the lack of an adequate VOGM animal model. Read More

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http://dx.doi.org/10.3171/2017.9.PEDS17365DOI Listing
April 2018
40 Reads

The role of endoscopy in the treatment of hydrocephalus associated with aneurysmal malformation of the vein of Galen.

Childs Nerv Syst 2018 04 16;34(4):593-595. Epub 2018 Jan 16.

Departement of Neurosurgery, National Institute of Neurology "Mongi Ben Hmida" of Tunis, Faculty of Medecine of Tunis, University of Tunis El Manar, 1007, Tunis, Tunisia.

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http://link.springer.com/10.1007/s00381-017-3717-2
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http://dx.doi.org/10.1007/s00381-017-3717-2DOI Listing
April 2018
12 Reads