Neurology 2022 02 8;98(7):292-295. Epub 2021 Dec 8.
From the Department of Clinical Neurosciences (J.I.R., A.K.);Department of Pediatrics (K.W., A.K., M.J.E.), Cumming School of Medicine, University of Calgary; Alberta Children's Hospital Research Institute (A.K., M.J.E.), University of Calgary; Hotchkiss Brain Institute (A.K., M.J.E.), University of Calgary, Alberta, Canada.
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant condition that is linked to a myriad of neurologic complications arising from vascular malformations of the brain, spinal cord, and lungs. Our case describes a previously healthy 3-year-old male who presented to hospital with fever of unknown origin and was found to have a brain abscess stemming from a pulmonary arteriovenous malformation (PAVM). This etiology was identified after a period of diagnostic delay; the medical team was suspicious for a proximal embolic source due to the presence of multiple tiny infarcts seen on MRI of the brain, but transthoracic echocardiogram and head and neck angiogram were unremarkable. Read More