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Adv Exp Med Biol 2021 ;1269:223-227

Universal Sport Health Science Laboratory, Department of Human and Engineered Environmental Studies, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan.

Autonomic disorders such as orthostatic hypotension often become a problem during the early mobilization of poststroke patients. We reported that the prefrontal cortex (PFC) oxyhemoglobin changes at rest are often on the right, and a positive correlation was observed between the left and right activity balance and the change in oxy-Hb. In this study, we focused on the asymmetrical changes associated with the standing load from rest. Read More

Stud Health Technol Inform 2021 May;279:46-53

University of Bergamo, Bergamo, Italy.

Background: Telerehabilitation represents a new cutting-edge method in the treatment of patients suffering from motor and cognitive disorders caused by stroke. Even if there exist dedicated devices able to track patients' movements to evaluate the performed rehabilitation exercises, they require specific settings necessary for a correct and simple use at the patient's home. If we consider the recent pandemic situation and the lockdown condition, which made difficult the access to these products, post stroke patients may be not able to perform home rehabilitation. Read More

Cochrane Database Syst Rev 2021 May 7;5:CD010876. Epub 2021 May 7.

REHPA, The Danish Knowledge Centre for Rehabilitation and Palliative Care, Odense University Hospital, Nyborg, Denmark.

Background: The impact of exercise-based cardiac rehabilitation (CR) following heart valve surgery is uncertain. We conducted an update of this systematic review and a meta-analysis to assess randomised controlled trial evidence for the use of exercise-based CR following heart valve surgery.

Objectives: To assess the benefits and harms of exercise-based CR compared with no exercise training in adults following heart valve surgery or repair, including both percutaneous and surgical procedures. Read More

Dimens Crit Care Nurs 2021 Mar-Apr 01;40(2):118-124

Background: Nurses caring for intensive care patients diagnosed with an aneurysmal subarachnoid hemorrhage (aSAH) conduct frequent neurological assessments and vital signs over an extended period during which patients are at risk of vasospasm. The frequency of assessments can negatively impact sleep, resulting in altered thought processes and mood, including delirium. There are 2 types of sleep during the night: non-rapid eye movement (non-REM) sleep and REM sleep (also called stage R). Read More

Adv Exp Med Biol 2021 ;1317:131-145

School of Life Sciences, University of Glasgow, Glasgow, UK.

Worldwide, it is estimated that millions of individuals suffer from a neurological disorder which can be the result of head injuries, ischaemic events such as a stroke, or neurodegenerative disorders such as Parkinson's disease (PD) and multiple sclerosis (MS). Problems with mobility and hemiparesis are common for these patients, making daily life, social factors and independence heavily affected. Current therapies aimed at improving such conditions are often tedious in nature, with patients often losing vital motivation and positive outlook towards their rehabilitation. Read More

J Occup Health 2021 Jan;63(1):e12220

Department of Mechanical Engineering, Universiti Sains Malaysia, Malaysia.

Objective: Prolonged exposure to hand-arm vibration (HAV) at the workplace is associated with hand-arm vascular syndrome (HAVS). This study aimed to determine the prevalence and the factors associated with the vascular and neurological complications of HAVS among tire shop workers in Kelantan, Malaysia.

Methods: A cross-sectional study involving 200 tire shop workers from two districts in Kelantan was conducted. Read More

Front Pharmacol 2021 15;12:668714. Epub 2021 Apr 15.

Department of Acupuncture Rehabilitation, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.

We used bibliometric methods to evaluate the global scientific output of research on Piezo channels and explore the current status and trends in this field over the past decade. Piezo channel-related studies published in 2010-2020 were retrieved from Web of Science. The R bibliometrix package was used for quantitative and qualitative analyses of publication outputs and author contributions. Read More

J Formos Med Assoc 2021 Apr 29. Epub 2021 Apr 29.

Department of Medical Rehabilitation, "Carol Davila" University of Medicine and Pharmacy, 041914, Bucharest, Romania; Neuromuscular Department, Clinical Emergency Hospital "Bagdasar Arseni", 041914, Bucharest, Romania.

Ten patients suffering from residual symptoms after the resolution of COVID-19, which manifested as fatigue in the lower limbs, have been submitted to nerve conduction studies. Motor demyelinating neuropathy features mainly of the tibial nerves but also the peroneal, median, and ulnar nerves were objectified. These findings might be considered as new neurological characteristics of SARS-CoV-2 infection. Read More

Sensors (Basel) 2021 Apr 15;21(8). Epub 2021 Apr 15.

Department of Software Convergence, Graduate School, Soonchunhyang University, 22, Soonchunhyang-ro, Asan City 31538, Chungnam-do, Korea.

With aging, cerebrovascular diseases can occur more often. Stroke cases involve hemiplegia, which causes difficulties in performing activities of daily living. Existing rehabilitation treatments are based on the subjective evaluation of the therapist as the need for non-contact care arises; it is necessary to develop a system that can self-rehabilitate and offer objective analysis. Read More

J Clin Med 2021 Apr 15;10(8). Epub 2021 Apr 15.

Department of Medical Rehabilitation, "Carol Davila" University of Medicine and Pharmacy, 041914 Bucharest, Romania.

Background: This study aimed to compare the effectiveness of radial extracorporeal shockwave and ultrasound therapies in adult patients with idiopathic scoliosis in terms of pain, disability, and quality of life.

Methods: Forty-eight patients with idiopathic scoliosis were randomly divided into three groups of 16: shockwave, ultrasound, and control. The patients were evaluated at admission (day one) and at discharge (day 14) for pain, by using the visual analogue scale; for disability, by using the Oswestry disability index; and for the quality of life, with short form-36. Read More

Int J Mol Sci 2021 Apr 5;22(7). Epub 2021 Apr 5.

Instituto Português de Oncologia de Lisboa Francisco Gentil (IPOLFG), Rua Prof. Lima Basto, 1099-023 Lisboa, Portugal.

Anti-angiogenic therapy is an old method to fight cancer that aims to abolish the nutrient and oxygen supply to the tumor cells through the decrease of the vascular network and the avoidance of new blood vessels formation. Most of the anti-angiogenic agents approved for cancer treatment rely on targeting vascular endothelial growth factor (VEGF) actions, as VEGF signaling is considered the main angiogenesis promotor. In addition to the control of angiogenesis, these drugs can potentiate immune therapy as VEGF also exhibits immunosuppressive functions. Read More

Zhongguo Zhen Jiu 2021 Apr;41(4):387-90

Department of Acupuncture and Moxibustion, First Affiliated Hospital of Guangzhou University of CM, Guangzhou 510405, Guangdong Province.

Objective: To compare the therapeutic effect between rehabilitation robot rehabilitation training synchronizing acupuncture exercise therapy and simple acupuncture exercise therapy on lower limb function and life activity ability for postoperative patients with hip fracture.

Methods: A total of 50 elderly postoperative patients with hip fracture were randomly divided into an observation group and a control group, 25 cases in each group. Both groups were treated with acupuncture at hip three points of the affected side and lateral line 1 of vertex, anterior oblique parietotemporal line of the healthy side, hip three needles were retained for 30 min. Read More

Zhongguo Zhen Jiu 2021 Apr;41(4):359-64

American TCM Society, New York NY 10016, USA.

Professor ' team from Chengdu University of TCM published in on July 29, 2019, which demonstrates that acupuncture as an adjunctive therapy is safety and effective for mild and moderate chronic stable angina. Sixteen experts at home and abroad conducted serious discussions on the research design, evaluation methods, principles and mechanisms, clinical significance and enlightenment of future acupuncture research, and provided practical suggestions for acupuncture and moxibustion to go global and gain international recognition. Read More

Zh Nevrol Psikhiatr Im S S Korsakova 2021 ;121(3. Vyp. 2):53-59

Vladimirsky Moscow Regional Research Clinical Institute, Moscow, Russia.

Objective: To assess the possibility of using the integral indicators of thrombodynamics to improve the safety of rehabilitation measures in patients in the recovery period of stroke.

Material And Methods: A prospective study included 52 patients in the recovery period of stroke. To compare the effect of the intensity of physical activity on the change in the integral indicators of thrombodynamics in accordance with the objectives of the study, the patients were randomized into two groups. Read More

Zh Nevrol Psikhiatr Im S S Korsakova 2021 ;121(3. Vyp. 2):29-32

Irkutsk State Medical Academy of Postgraduate Education - Branch of the Medical Academy for Continuous Professional Education, Irkutsk, Russia.

A variety of structural and functional post-stroke disturbances demands an integrated clinical/diagnostic approach. Persistent hypoxemia due to disturbance of a saturation of blood oxygen in sleep can decrease the effectiveness of neurorehabilitation. In some cases of sleep apnea, the efficiency of continuous positive airway pressure therapy is insufficient and it should be combined with course neuroprotective therapy. Read More

Zh Nevrol Psikhiatr Im S S Korsakova 2021 ;121(3. Vyp. 2):16-21

Medical University of Karaganda, Karaganda, Kazakhstan.

Post-stroke cognitive impairment (PCI) is a common complication of stroke. PCI in most cases is associated with an increased risk of progression to dementia, with a progression rate of 8-15% per year. When post-stroke cognitive impairment reaches dementia, patients lose independence, professional and social maladjustment occurs, which, in turn, significantly worsen the quality of life and reduce the rehabilitation potential. Read More

Medicine (Baltimore) 2021 Apr;100(17):e25730

Department of Emergency Medicine, Laboratory of Emergency Medicine, Disaster Medical Center.

Background: Sleep disorders after stroke is one of the most common neuropsychiatric complications and is associated with increased risk of death and poor functional outcomes. Some evidence shows that patients with sleep disorders after stroke benefit from exercise intervention. However, this result is still conflicting. Read More

Medicine (Baltimore) 2021 Apr;100(17):e25657

School of Rehabilitation Medicine.

Background: Malnutrition is commonly observed after stroke and is closely associated with poor clinical outcomes. So, early nutrition support is particularly crucial for severe stroke patients. However, a significant number of critically ill patients are intolerant to enteral nutrition (EN). Read More

Medicine (Baltimore) 2021 Apr;100(17):e25596

Department of Neurology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, Sichuan Province, China.

Background: As the most common type of cerebrovascular disease, ischemic stroke is the disturbance of cerebrovascular circulation caused by various factors, with complex pathogenesis. At present, the molecular mechanism of ischemic stroke is still unclear, and there lacks early diagnostic markers. Therefore, there is an urgent need to find effective preventive measures, active diagnostic methods and rapid treatment measures. Read More

J Med Case Rep 2021 Apr 28;15(1):205. Epub 2021 Apr 28.

Department of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan.

Background: The median sternotomy approach in sleeve pneumonectomy enables diseased lung ventilation in selected cases, which may reduce the difficulty in achieving anastomosis under intubation of the left main bronchus. However, with median sternotomy, the ascending aorta requires repeated mobilization to expose the operative field for anastomosis, which can cause an aortogenic embolic stroke.

Case Presentation: A 70-year-old Asian man presenting 6 months after developing hemoptysis was diagnosed with right upper lobe lung cancer (stage T4N0M0), invading the lower trachea and basal bronchus. Read More

Pharm Biol 2021 Dec;59(1):513-524

The Affiliated Rehabilitation Hospital, Fujian University of Traditional Chinese Medicine, Fuzhou, China.

Context: Alisol A 24-acetate has been used to treat vascular diseases. However, the underlying mechanisms still remain unclear.

Objective: The present study evaluated the antiapoptotic effect of alisol A 24-acetate on brain microvascular endothelial cells (BMECs) and explored the underlying mechanisms. Read More

Br J Pharmacol 2021 Apr 26. Epub 2021 Apr 26.

Department of Neurosurgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, 210008, Jiangsu, China.

Background And Purpose: Dioscin possesses multiple biologic activities and is beneficial for cardiovascular and cerebral vascular diseases. Here we investigated the protective effects of dioscin against subarachnoid hemorrhage (SAH) and the involvement of underlying molecular mechanisms.

Experimental Approach: Dioscin was administered after SAH. Read More

Vopr Kurortol Fizioter Lech Fiz Kult 2021 ;98(2):5-9

Novosibirsk State Medical University, Novosibirsk, Russia.

The disability of post-stroke patients is one of the most important problems of the modern medical community requiring the improvement of existing rehabilitation technologies through the wider use of non-drug treatment methods among which the most accessible are various modifications of reflexotherapy.

Objective: To evaluate the effectiveness of the combined reflexology technique, including the combined use of classical acupuncture, su-jok and cranial acupuncture in the early rehabilitation of patients after ischemic stroke.

Material And Methods: Examination and course of early neurorehabilitation were carried out in 80 patients aged 47-78 years. Read More

J Trauma Acute Care Surg 2021 05;90(5):880-890

From the Division of Trauma, Emergency Surgery and Surgical Critical Care (O.A., A.M., L.N., K.L., K.A.B., M.E.M., C.K., A.G., M.A.C., L.R.M., H.M., B.B.-K., J.P., J.F., N.S., A.M., C.P., P.F., D.K., J.L., G.C.V., H.M.A.K.), and Division of Pulmonary Critical Care (M.R.F.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

Background: We sought to describe characteristics, multisystem outcomes, and predictors of mortality of the critically ill COVID-19 patients in the largest hospital in Massachusetts.

Methods: This is a prospective cohort study. All patients admitted to the intensive care unit (ICU) with reverse-transcriptase-polymerase chain reaction-confirmed severe acute respiratory syndrome coronavirus 2 infection between March 14, 2020, and April 28, 2020, were included; hospital and multisystem outcomes were evaluated. Read More

J Cardiovasc Med (Hagerstown) 2021 Apr 20. Epub 2021 Apr 20.

Division of Cardiology, Hospital 'P. Pederzoli', Peschiera del Garda, VR San Antonio Hospital, San Daniele del Friuli, UD Cardiology Unit, Policlinico Casilino, Rome Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Padua Institute of Sport Medicine and Science, Rome Referral Center for Cardiomyopathies, Careggi University Hospital, Florence Division of Cardiology, San Filippo Neri Hospital, Rome Department of Cardiothoracic Sciences, Monaldi Hospital, Second University of Naples, Naples Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila Cardiovascular Center, ASUITS, Maggiore Hospital, Trieste Sports Medicine Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome Sports Medicine and Cardiovascular Rehabilitation Unit, Cardiovascular Department, PF Calvi Hospital, Noale, Venice Interventional Cardiology Unit, S. Maria Nuova Hospital, Reggio Emilia Ospedale Maggiore Di Crema, Crema Cardiology Unit, Villa Verde Hospital, Taranto Department of Cardiology, Carpi Hospital, Carpi Cardiology, Department of Life, Health and Environmental Sciences|, University of L'Aquila, L'Aquila Department of Cardiology, University of Rome 'Tor Vergata', Rome Center for Sports Medicine, Treviso Unit of Grown-up Congenital Heart Disease, Monaldi Hospital, Naples Cardiovascular Department, Azienda Sanitaria Universitaria Integrata, University of Trieste (ASUITS), Trieste, Italy.

Since 1989, SIC Sport and a FMSI, in partnership with leading Italian Cardiological Scientific Associations (ANCE, ANMCO and SIC) have produced Cardiological Guidelines for Completive Sports Eligibility for athletes with heart disease (COCIS -- 1989, 1995, 2003, 2009 and 2017). The English version of the Italian Cardiological Guidelines for Competitive Sports Eligibility for athletes with heart disease was published in 2013 in this Journal. This publication is an update with respect to the document previously published in English in 2013. Read More

Medicine (Baltimore) 2021 Apr;100(16):e25550

King Abdulaziz Medical City, National Guard, Riyadh, Saudi Arabia.

Abstract: Stroke is the major leading cause of death and severe long-term disability worldwide. The consequences of stroke, aside from diminished survival, have a significant impact on an individual's capability in maintaining self-autonomy and life satisfaction (LS). Thus, this study aimed to assess LS and other specific domains of LS in stroke survivors following their first-ever stroke, and to describe the relationship using socio-demographic and stroke-related variables. Read More

Medicine (Baltimore) 2021 Apr;100(16):e25212

Department of Internal Medicine and Neuroscience.

Abstract: Gait rehabilitations have been abundantly performed for post-stroke patients, because gait is the most important factor for the return of post-stroke patients to daily life. However, conventional uniform gait rehabilitations tend to be tedious and reduce motivation. The aim of this study was to contribute to the development of personalized rehabilitation of gait by identifying differences in gait recovery pattern according to the paralyzed side of post-stroke patients. Read More

BMC Psychiatry 2021 04 20;21(1):202. Epub 2021 Apr 20.

Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangdong Cardiovascular Institute, No.106 Zhongshan Er Road, Yuexiu District, Guangzhou, 510080, People's Republic of China.

Background: Depression and anxiety are two common mood problems among patients with cardiovascular disease (CVD) and are associated with poor cardiac prognoses. The comorbidity of depression and anxiety is considered to be a more severe psychological status than non-comorbid mood disorders. However, little is known about the relationship between depression or anxiety and noncardiac readmission. Read More

Stroke 2021 05 21;52(5):e117-e130. Epub 2021 Apr 21.

Neurosurgery Department, Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Turkey (O.A., M.M.H.).

[Figure: see text]. Read More

J Rehabil Med 2021 04 28;53(4):jrm00186. Epub 2021 Apr 28.

Department for Rehabilitation and Secondary Prevention, Federal State Budgetary Institution National Medical Research Centre for Preventive Medicine of the Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation.

Objective: To measure progress towards introducing a 3-phase rehabilitation programme, based on the multidisciplinary approach, for patients with cardiovascular diseases.

Methods: Seventeen hospital and outpatient medical centres from 13 regions of the Pilot Project. Baseline questionnaires assessed the involvement of multidisciplinary teams, staffing, and the equipment in healthcare facilities. Read More