Rambam Maimonides Med J 2018 04 19;9(2). Epub 2018 Apr 19.
Porphyria Center, Rabin Medical Center, Beilinson Hospital, Petach Tikva, Israel.
The porphyrias are a group of rare metabolic disorders, inherited or acquired, along the heme biosynthetic pathway, which could manifest with neurovisceral and/or cutaneous symptoms, depending on the defective enzyme. Neurovisceral porphyrias are characterized by acute attacks, in which excessive heme production is induced following exposure to a trigger. An acute attack usually presents with severe abdominal pain, vomiting, and tachycardia. Read More