269 results match your criteria Varicose Veins and Spider Veins

A narrative review of the quality of life scales specific for chronic venous diseases.

Medicine (Baltimore) 2021 May;100(20):e25921

Department of Vascular Surgery, West China Hospital, Sichuan University, Chengdu, China.

Abstract: To review the various quality of life (QoL) scales specific for chronic venous diseases (CVDs) and provide guidance and a reference for researchers to select the ideal measurement scale before studying QoL in patients with CVDs.The EBSCO, Ovid, PubMed, Wanfang, and CNKI databases were searched for the keywords "vein," "quality of life," and "scale/questionnaire," and various scales used to measure QoL in patients with CVDs. The QoL aspects were investigated and researched, and then, the search results were screened and summarized. Read More

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Adjuvant radiofrequency thermocoagulation improves the outcome of liquid sclerotherapy in the treatment of spider veins of the leg: A pilot study.

Phlebology 2021 Apr 4:2683555211006534. Epub 2021 Apr 4.

Cardiovascular Surgery, Ministry of Health Ankara City Hospital, Ankara, Turkey.

Objective: This study evaluated the effect of low-energy radiofrequency thermocoagulation added to standard liquid sclerotherapy on clinical outcomes of patients with venous insufficiency.

Patients And Method: We included 111 patients with spider veins CEAP/C1 stage. The patients were randomized into sclerotherapy (Group 1) and sclerotherapy + sclerotherapy immediately followed by low energy percutaneous RF thermocoagulation (Group 2) groups and followed up with same protocols prospectively. Read More

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Study of Flebogrif-A New Tool for Mechanical Sclerotherapy-Effectiveness Assessment Based on Animal Model.

Nanomaterials (Basel) 2021 Feb 21;11(2). Epub 2021 Feb 21.

Institute of Low Temperature and Structure Research, PAS, Okolna 2, 50-422 Wroclaw, Poland.

Sclerotherapy is the chemical occlusion of vessels using an intravenous injection of a liquid or foamed sclerosing agent that is used in the therapy of blood and lymphatic vessels malformations in the young, and for spider veins, smaller varicose veins, hemorrhoids and hydroceles in adults. This study aimed to assess the effectiveness of mechanosclerotherapy of venous veins with a new device-Flebogrif-based on an animal model. The experiment was performed on nine Polish Merino sheep weighing 40-50 kilograms. Read More

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February 2021

Initiation of reticular and spider veins, incompetent perforantes and varicose veins in the saphenous vein network of the rat.

Sci Rep 2020 09 21;10(1):15381. Epub 2020 Sep 21.

Department of Physiology, Semmelweis University, Tuzolto Str 37-47, 1094, Budapest, Hungary.

In an attempt to induce experimental varicosity, reverse perforant vein development was initiated in the rat leg by applying a chronic (14 and 32 weeks) partial stricture on the main branch of the deep femoral vein. At surfacing of the incompetent perforantes, typical reticular vein plaques and spider veins were identified by video-microscopy and quantitative histology. Deep vein blood was channeled by them into the saphenous vein system, the extra flow deforming these vessels, causing local dilations and broken course, even undulations of larger branches. Read More

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September 2020

Diffuse telangiectasia of the colon: A case report.

Medicine (Baltimore) 2020 Aug;99(34):e21106

Gastroenterology and Center of Digestive Endoscopy.

Rationale: Colonic telangiectasia, also known as colonic angiodysplasia, refers to arteriovenous malformations that occur in the colon, which are common vascular lesions in the GI tract.

Patient Concerns: We report a patient, who was admitted to our hospital for colonoscopy.

Diagnoses: Under a microscope, all the segments of the whole colon and the varicose veins showed multiple flaky spider-like telangiectasia changes. Read More

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Reducing hyperpigmentation after sclerotherapy: A randomized clinical trial.

J Vasc Surg Venous Lymphat Disord 2021 01 30;9(1):154-162. Epub 2020 Jul 30.

Instituto de Seguridad y Servicios Sociales de los Trabajadores del Gobierno y Municipios del Estado Baja California, Mexicali, Baja California, Mexico.

Objective: Sclerotherapy for the treatment of varicose veins is one of the most common medical procedures performed in the Western world, and hyperpigmentation is one of the most frequent, dreaded, minor adverse events. There has recently been some interest in investigating the inflammatory response of the local endothelium after sclerotherapy and the possible benefits of venoactive drugs because of their pleiotropic properties. The aim of this study was to evaluate whether adding a venoactive drug (sulodexide) to the standard sclerotherapy treatment protocol for patients with varicose veins can reduce the occurrence of postsclerotherapy hyperpigmentation. Read More

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January 2021

How Diluted Liquid Sodium Tetradecyl Sulphate Works in Varices with Competent Superficial Valves Versus Stockings Alone.

Pak J Biol Sci 2020 Jan;23(8):1018-1024

Background And Objective: Varicose veins are the most common complaints of referrals to vascular surgeons. Upon the cause, liquid sclerotherapy could be an efficient solution first in regard to competent main superficial valves. To find the impact of diluted liquid sclerotherapy in varices in patients with no superficial valve refluxes compare to whom wearing only stockings. Read More

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January 2020

A new automated system for the preparation of sclerosant foam: A study of the physical characteristics produced and the device settings required.

Phlebology 2020 Oct 7;35(9):724-733. Epub 2020 Jul 7.

Vascular Surgery, Clínica Vascular Barcelona, Barcelona, Spain.

Objectives: To determine the quality of sclerosant foam produced with an automated preparation system with multiple combinations of sclerosing agents, gases, and device settings.

Methods: Single-use mixing capsules filled with air or O/CO and polidocanol (0.25, 1, or 3%) or sodium tetradecyl sulfate (0. Read More

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October 2020

Clinical outcome of short-term compression after sclerotherapy for telangiectatic varicose veins.

J Vasc Surg Venous Lymphat Disord 2021 03 2;9(2):435-443. Epub 2020 Jun 2.

Department of Dermatology, University Medical Centre Schleswig-Holstein, Campus Luebeck, Luebeck, Germany.

Background: Sclerotherapy is considered to be the method of choice for the treatment of telangiectatic varicose veins (C1 veins). Whereas the use of compression stockings after sclerotherapy is recommended, little is known about the impact of compression on the outcome of sclerotherapy. The aim of this study was to assess the influence of compression on the outcome of injection sclerotherapy of C1 varicose veins. Read More

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[Local drugs in treating and decreasing the incidence of adverse reactions after sclerotherapy of telangiectasia].

Angiol Sosud Khir 2019 ;25(4):102-107

First Phlebological Centre, Moscow, Russia.

Aim: The purpose of the study was to assess efficacy and safety of heparin sodium gel 1000 IU/g and Detragel® in decreasing the incidence and treatment of the most common local adverse reactions in patients after endured sclerotherapy of reticular veins and telangiectasias.

Patients And Methods: Our open prospective observational study included a total of sixty 18-to-35-year-old female patients who after undergoing standardized sclerotherapy of reticular veins and telangiectasias on symmetrical portions of lower limbs were given a tube of heparin sodium gel 1000 IU/g or Detragel® to be applied onto the skin of one (left) lower limb in the projection of the sclerotherapy-exposed vessels 2-3 times daily for 10 days followed by putting on a compression class 2 (RAL standard) stocking. The women were allowed to use only the paired stocking on the contralateral extremity. Read More

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January 2020

Improper Potency and Impurities in Compounded Polidocanol

J Drugs Dermatol 2019 Nov;18(11):1124-1127

Polidocanol is an FDA-approved sclerosant indicated for treating uncomplicated spider veins and reticular veins in the lower extremities. Despite restrictions against compounding drugs that are essentially copies of FDA-approved or commercially available products, polidocanol is also available from compounding pharmacies and outsourcing facilites. Compounded drug products are not FDA-approved and have not undergone premarket FDA review for safety, effectiveness, and quality. Read More

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November 2019

[New methods of interventional treatment of varicose veins].

Pol Merkur Lekarski 2019 Apr;46(274):153-156

LuxMed Group Warsaw, Poland.

Lower limb veins diseases belong to frequently occurring disease syndromes. It covers 62% of adult Poles. They are not only an aesthetic problem. Read More

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Inter-arterial saphenofemoral junction: A rare anatomical variation.

Ilkay S Idilman

J Clin Ultrasound 2019 Sep 22;47(7):439-441. Epub 2019 Mar 22.

Faculty of Medicine, Department of Radiology, Hacettepe University, Ankara, Turkey.

Several anatomical variations involving the great saphenous vein have been described in the literature. Some of them concern the saphenofemoral junction, including duplication, ectasia, and different numbers of tributaries. In this case series, a rare, distinct variation, the inter-arterial saphenofemoral junction was reported. Read More

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September 2019

Safety Profile of Sclerosing Agents: An Analysis From the World Health Organization Pharmacovigilance Database VigiBase.

Dermatol Surg 2019 12;45(12):1517-1528

Clinical Pharmacology Department INSERM CIC1406, Grenoble Alpes University Hospital, Grenoble, France.

Background: Several sclerosing agents are used to treat chronic venous diseases. Although they do not seem to differ in terms of efficacy, their safety profiles might differ.

Objective: To compare the safety profile of sclerosing agents through an analysis of the World Health Organization pharmacovigilance database. Read More

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December 2019

Effects of 1064-nm Nd:YAG long-pulse laser on polidocanol microfoam injected for varicose vein treatment: a controlled observational study of 404 legs, after 5-year-long treatment.

Lasers Med Sci 2019 Sep 1;34(7):1325-1332. Epub 2019 Feb 1.

Fundación Antoni de Gimbernat, Instituto Médico Vilafortuny, Av. Vilafortuny 31, Cambrils, E43850, Tarragona, Spain.

Sclerotherapy continues to be the treatment of choice for varicose veins in the legs. However, isolated treatment using microfoam or lasers requires a high number of sessions to eliminate them. In 2013, we published results about the efficacy and safety 3 years after the combined treatment with microfoam injections and subsequent application of Nd:YAG laser. Read More

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September 2019

A Pial Arteriovenous Fistula in Infancy as the Presenting Manifestation of Hereditary Hemorrhagic Telangiectasia.

World Neurosurg 2019 Feb 1;122:322-325. Epub 2018 Nov 1.

Department of Neurosurgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.

Background: Pial arteriovenous fistulas (PAVFs) are rare, accounting for 1.6%-4.7% of all intracranial vascular malformations. Read More

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February 2019

[Cryocompression sclerotherapy of reticular veins and teleangiectasias].

Angiol Sosud Khir 2018;24(3):92-97

Russian National Research Medical University named after N.I. Pirogov under the RF Ministry of Public Health, Moscow, Russia.

Compression serves as an important component for carrying out successful and safe phlebosclerosing treatment. At the same time, the necessity of wearing compression hosiery or bandages is associated with known limitations and objections of patients, especially in a hot season. We comparatively assessed efficacy of usual compression stockings and a short-term pneumatic bandage with cryoelements while carrying out sclerosing treatment of dilated intradermal veins. Read More

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December 2018

[Laser surgery on varicose veins].

Magy Seb 2018 09;71(3):134-141

Á+B Gyógycentrum 1081 Budapest, Népszínház u. 46.

Introduction: With the development of medicine, technical inventions have been intoduced into the therapy of varicose veins, such as ultrasound examination and laser treatment.

Patients And Methods: Over 11 years 1729 laser surgery were performed on varicose veins. Junctions of saphenous veins, saphenous stems and perforator veins were treated with lasers, but reticular and spider veins were treated with other methods. Read More

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September 2018

Liquid and Foam Sclerotherapy for Spider and Varicose Veins.

Surg Clin North Am 2018 Apr 22;98(2):415-429. Epub 2017 Dec 22.

Lake Washington Vascular Surgeons, 1135 116th Avenue Northeast, Suite 305, Bellevue, WA 98004, USA.

Sclerotherapy has wide applicability in treating venous disease at every stage of clinical disease. The various sclerosant drugs and formulations each have unique properties, utilities, and side effects. Treating physicians should be aware of the differences between agents, accounting for disease presentation, vein characteristics, and patient comorbidities when selecting the appropriate sclerosing agents. Read More

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An Evidence-Based Review of Off-Label Uses of Polidocanol.

Curr Clin Pharmacol 2017 ;12(4):223-230

Drug Applied Research Center, Department of Pharmacology and Toxicology, School of Pharmacy, Tabriz University of Medical Sciences, Tabriz 51656-65811, Iran.

Background: Polidocanol is approved for its competence in the treatment of varicose veins and spider veins; however, unfortunately, many of its off-label uses are still underappreciated.

Objective: Lack of an appropriate comprehensive review for off-label uses of this medication troubles physicians about making evidence-based decisions on prescribing it for its various outstanding off-label uses. This article attempts to provide physicians with the latest information concerning successful and unsuccessful use of polidocanol as an alternative treatment for esophageal and gastric varices, tendinopathy and epicondylitis, vascular malformations, varicocele, hydrocele and spermatocele, aneurysmal bone cysts, itching, management of gastrointestinal bleeding, simple renal cysts, reducing the incidence and severity of radio-induced dermatitis and hemorrhoids. Read More

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Magnolol inhibits venous remodeling in mice.

Sci Rep 2017 12 19;7(1):17820. Epub 2017 Dec 19.

Institute of Physiology and Pathophysiology, Division of Cardiovascular Physiology, Heidelberg University, Heidelberg, Germany.

Due to gravity the venous vasculature in the lower extremities is exposed to elevated pressure levels which may be amplified by obesity or pregnancy. As a consequence, venules dilate and may be slowly transformed into varicose or spider veins. In fact, chronically elevated venous pressure was sufficient to cause the corkscrew-like enlargement of superficial veins in mice. Read More

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December 2017

[New Developments in Compression Treatment].

Dtsch Med Wochenschr 2017 May 28;142(9):679-686. Epub 2017 Apr 28.

Patients with peripheral arterial occlusive disease who show an ankle arterial pressure of minimum 60 mmHg can be decongested by use of special padded bandages. Afterwards, medical compression stockings (class 1) with high strength and less elasticity are recommended. Mobile patients seem to benefit from progressive compression therapy with highest pressure above the calf. Read More

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Quantification of early cutaneous manifestations of chronic venous insufficiency by automated analysis of photographic images: Feasibility and technical considerations.

Phlebology 2018 Jun 12;33(5):309-314. Epub 2017 Apr 12.

2 Laboratoires Innothéra, Arcueil, France.

We postulate that blue telangiectasia and brownish pigmentation at ankle level, early markers of chronic venous insufficiency, can be quantified for longitudinal studies of chronic venous disease in Caucasian people. Objectives and methods To describe a photographic technique specially developed for this purpose. The pictures were acquired using a dedicated photo stand to position the foot in a reproducible way, with a normalized lighting and acquisition protocol. Read More

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Postpartum Varicose Veins: Supplementation with Pycnogenol or Elastic Compression-A 12-Month Follow-Up.

Int J Angiol 2017 Mar 29;26(1):12-19. Epub 2014 May 29.

Department of Biomedical Sciences, Irvine 3 Labs, CH-PE University, Pescara, Italy.

This open registry aimed to evaluate the clinical evolution of postpartum varicose veins (VVs), in healthy women after the second pregnancy, how these veins regain shape and competence, and possible treatments. The registry included two groups of women: (1) those who used elastic compression stockings, and (2) who used an oral venotonic agent (Pycnogenol, 100 mg/d). A total of 12 evaluation targets were established. Read More

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Extensive Acquired Telangiectasias: Comparison of Generalized Essential Telangiectasia and Cutaneous Collagenous Vasculopathy.

Actas Dermosifiliogr 2017 Apr 21;108(3):e21-e26. Epub 2016 Sep 21.

Servicio de Anatomía Patológica, Hospital Universitari Son Espases, Palma de Mallorca, España.

The late development of symmetrical, ascending telangiectasias over an extensive area of the skin with no associated systemic manifestations is a common presentation of generalized essential telangiectasia (GET). It was recently suggested that cutaneous collagenous vasculopathy (CCV) is clinically identical to GET but that the 2 conditions can be distinguished by their distinctive histopathologic findings. We present 2 patients, both women, with multiple telangiectasias and describe the histopathologic findings that led to the diagnoses of GET and CCV. Read More

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[Practical Aspects of Sclerotherapy].

Wien Med Wochenschr 2016 Jun 5;166(9-10):302-4. Epub 2016 Jul 5.

Klinik für Dermatologie, Venerologie und Allergologie, Venenzentrum der dermatologischen und gefäßchirurgischen Kliniken, Ruhr-Universität Bochum, Gudrunstr. 56, 44791, Bochum, Deutschland.

Sclerotherapy is an important part of the treatment of varicose veins. It may also be performed in patients with contraindications for operative procedures. By adjusting the mode of application (liquid or foam) and the concentration it can be used for the treatment of all vein types. Read More

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[Transitory (evening) venous reflux in patients with intracutaneous varicosity and medicamentous correction thereof].

Angiol Sosud Khir 2016 ;22(2):110-6

Chair of Surgical Diseases and Urology, Omsk State Medical University, Omsk, Russia.

The authors carried out a study aimed at revealing transitory refluxes along the great saphenous vein (GSV) in patients with intracutaneous varicosity, and at investigating the possibility of removing them by means of preparations of micronized purified flavonoid fraction (MPFF). The study included a total of one hundred and forty-seven 21-to-47-year-old (mean age 31±4.4 years) women presenting with cutaneous varicosity (class C1s). Read More

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Orthostatic-loading-induced transient venous refluxes (day orthostatic loading test), and remedial effect of micronized purified flavonoid fraction in patients with telangiectasia and reticular vein.

Int Angiol 2017 Apr 17;36(2):189-196. Epub 2016 Jun 17.

Department of Surgical Diseases, Omsk State Medical University, Omsk, Russia.

Background: Orthostatic loading can induce transient venous reflux (TVR). Among patients with telangiectasia and reticular varices, we determined the proportion that developed TVR after a day of orthostatic loading (DOL test), and investigated the remedial effects of micronized purified flavonoid fraction (MPFF).

Methods: All 96 patients enrolled in this study had telangiectasia and reticular varices. Read More

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Sclerotherapy of telangiectasias or spider veins in the lower limb: A review.

Lily Thomson

J Vasc Nurs 2016 Jun;34(2):61-2

Section of Vascular Surgery, Health Sciences Centre, Vascular Research Lab, Winnipeg, Manitoba, Canada; St. Boniface General Hospital, Operating Room, Winnipeg, Manitoba, Canada. Electronic address:

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