13,548 results match your criteria Vaginitis


[Preliminary study of the clinical value of colposcopy in diagnosing vagina invasion in cervical cancer].

Zhonghua Fu Chan Ke Za Zhi 2020 May;55(5):322-326

Department of Gynecologic Oncology, Xuzhou Hospital Affiliated to Jiangsu University/Xuzhou Cancer Hospital, Xuzhou 221000, China.

To explore the preliminary clinical values of colposcopy in the diagnosis of vaginal invasion in cervical cancer. A retrospective review of the clinical records of patients (31 cases) with cervical cancer treated in Xuzhou Cancer Hospital from April 2015 to August 2019. For those with early-stage cervical cancer and the vagina invasion being difficult to be determined, those with advanced cervical cancer and the scope of vaginal invasion being difficult to be judged, and those with obvious vaginal tumor and underexposed cervix or inconspicuous cervical lesion and the primary location needing to be identified, colposcopy-guided vaginal and cervix biopsy were performed before treatment. Read More

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http://dx.doi.org/10.3760/cma.j.cn112141-20200211-00093DOI Listing

An isolated vaginal metastasis from intestinal signet ring cell carcinoma: a case report and literature review.

BMC Cancer 2020 May 27;20(1):478. Epub 2020 May 27.

The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.

Background: Isolated vaginal metastases from intestinal signet ring cell carcinoma are extremely rare. There are no reported cases in the domestic or foreign literature. The characteristics of such cases of metastasis remain relatively unknown. Read More

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http://dx.doi.org/10.1186/s12885-020-06950-xDOI Listing

Hyperammonemia by Ureaplasma urealyticum Pneumonia after Lung Transplantation.

Respir Med Case Rep 2020 6;30:101080. Epub 2020 May 6.

Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Martinistr.52, D-20246, Hamburg, Germany.

Ureaplasma urealyticum is a commensal of the female genital tract and can be detected as a pathogen in urethritis and vaginitis. Its importance as a respiratory pathogen beyond the field of neonatology remains controversial. We report a case of Ureaplasma-pneumonia in a recently lung-transplanted patient, with hyperammonemic syndrome. Read More

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http://dx.doi.org/10.1016/j.rmcr.2020.101080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218208PMC

Trichomoniasis in a tertiary hospital of Madrid, Spain (2013-2017): prevalence and pregnancy rate, coinfections, metronidazole resistance, and endosymbiosis.

Parasitol Res 2020 Jun 14;119(6):1915-1923. Epub 2020 May 14.

Departamento de Microbiología y Parasitología, Facultad de Farmacia, Universidad Complutense de Madrid, Madrid, Spain.

Trichomoniasis is the most prevalent curable sexually transmitted infection (STI) worldwide and a risk factor for the acquisition of other STIs and adverse pregnancy outcomes. The objectives of this study were to determine the prevalence of T. vaginalis and related coinfections in women attending a third-level hospital of Madrid (Spain). Read More

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http://dx.doi.org/10.1007/s00436-020-06688-2DOI Listing

Randomized Trial of Lactin-V to Prevent Recurrence of Bacterial Vaginosis.

N Engl J Med 2020 05;382(20):1906-1915

From the Departments of Obstetrics, Gynecology, and Reproductive Sciences (C.R.C., S.N., A.H.) and Laboratory Medicine (L.G., S. Miller), University of California, San Francisco, San Francisco, the Department of Family Medicine, University of California, San Diego, San Diego (S. Morris), and Osel, Mountain View (T.P.) - all in California; Emmes, Rockville, MD (M.R.W., J.P.); the Department of Medicine, Ruth M. Rothstein CORE Center and Stroger Hospital of Cook County Health, Rush University Medical Center, Chicago (A.L.F.); and the Division of Infectious Diseases, Department of Medicine, Washington University, St. Louis (H.R.).

Background: Bacterial vaginosis affects 15 to 50% of women of reproductive age, and recurrence is common after treatment with an antibiotic agent. The high incidence of recurrence suggests the need for new treatments to prevent recurrent bacterial vaginosis.

Methods: We conducted a randomized, double-blind, placebo-controlled, phase 2b trial to evaluate the ability of CTV-05 (Lactin-V) to prevent the recurrence of bacterial vaginosis. Read More

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http://dx.doi.org/10.1056/NEJMoa1915254DOI Listing

The Genitourinary Syndrome of Menopause: An Overview of the Recent Data.

Cureus 2020 Apr 8;12(4):e7586. Epub 2020 Apr 8.

Urogynecology Unit, Alexandra Hospital-National and Kapodistrian University of Athens, Athens, GRC.

The genitourinary syndrome of menopause (GSM) is a relatively new term for the condition previously known as vulvovaginal atrophy, atrophic vaginitis, or urogenital atrophy. The term was first introduced in 2014. GSM is a chronic, progressive, vulvovaginal, sexual, and lower urinary tract condition characterized by a broad spectrum of signs and symptoms. Read More

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http://dx.doi.org/10.7759/cureus.7586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212735PMC

Does Aerobic Vaginitis Have Adverse Pregnancy Outcomes? Prospective Observational Study.

Infect Dis Obstet Gynecol 2020 18;2020:5842150. Epub 2020 Jan 18.

Department of Pediatrics and Neonatology, Faculty of Medicine, Cairo University, Cairo, Egypt.

Background: Aerobic vaginitis (AV) is an aberration within the balanced vaginal microbiota. Only few reports have documented the adverse pregnancy outcomes related to AV. Nonetheless, the exact role of AV in pregnancy and the potential benefit of its screening need further study. Read More

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http://dx.doi.org/10.1155/2020/5842150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201818PMC
January 2020

Molecular identification and antifungal susceptibility profile of yeast from vulvovaginal candidiasis.

BMC Infect Dis 2020 Apr 19;20(1):287. Epub 2020 Apr 19.

Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen, 518036, China.

Background: Accurate identification Candida is important for successful therapy and epidemiology study. The aim of research is to study API 20C yeast identification system identification rate by using molecular identification as gold standard and tested the antifungal susceptibility of Candida from patients with vulvovaginal candidiasis (VVC).

Methods: In total, 3574 yeast isolates were obtained from patients with VVC. Read More

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http://dx.doi.org/10.1186/s12879-020-04985-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216708PMC

Prevalence of vulvovaginal candidiasis among pregnant women in the Ho municipality, Ghana: species identification and antifungal susceptibility of Candida isolates.

BMC Pregnancy Childbirth 2020 May 6;20(1):266. Epub 2020 May 6.

Microbiology Department, University of Ghana Medical School, Accra, Ghana.

Background: Candida is the leading cause of vaginitis, and 75% of women have at least one episode of infection in their lives, with pregnancy being a predisposing factor. If left untreated, vulvovaginal candidiasis (VVC) can lead to chorioamnionitis with subsequent abortion, prematurity and congenital infection of the neonate. We aimed to determine the prevalence of VVC, identify the recent and most frequently occurring species of Candida in pregnant women, and determine the most effective antifungal drug of choice for treatment. Read More

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http://dx.doi.org/10.1186/s12884-020-02963-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201979PMC
May 2020
2.190 Impact Factor

anti-inflammatory potential of phloretin microemulsion as a new formulation for prospective treatment of vaginitis.

Pharm Dev Technol 2020 May 13:1-6. Epub 2020 May 13.

Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.

Phloretin is a promising polyphenolic compound known for its anti-inflammatory properties, but its poor solubility and low bioavailability hinder its clinical applicability. Till current date, its potential in the treatment of vaginitis has not been explored, and only very few papers reported its formulation as nanoparticles to overcome its pharmaceutical challenges. Therefore, in the current study, phloretin was formulated in microemulsion of 11 nm size, and its anti-inflammatory properties were explored using histamine and IL-6 release inhibition assays, protease inhibition assay, and membrane stabilization potential. Read More

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http://dx.doi.org/10.1080/10837450.2020.1764032DOI Listing

The use of 3 selected lactobacillary strains in vaginal probiotic gel for the treatment of acute Candida vaginitis: a proof-of-concept study.

Eur J Clin Microbiol Infect Dis 2020 Apr 30. Epub 2020 Apr 30.

Department of Bioscience Engineering, Research group Environmental Ecology and Microbiology, University of Antwerp, Antwerp, Belgium.

In vitro studies suggest that certain probiotic bacterial strains have potential activity against opportunistic infections such as Candida. There are few in vivo trials using probiotics as a single treatment for acute Candida vulvovaginitis (CV). In this open-label, proof-of-concept study, selected Lactobacillus strains were tested in women with acute Candida vaginitis. Read More

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http://dx.doi.org/10.1007/s10096-020-03868-xDOI Listing

Diagnosis and Treatment of Vaginal Discharge Syndromes in Community Practice Settings.

Clin Infect Dis 2020 Apr 30. Epub 2020 Apr 30.

Magee-Womens Research Institute, Pittsburgh, Pennsylvania, USA.

Background: Although vaginal symptoms are common, diagnosis of bacterial vaginosis (BV), vulvovaginal candidiasis (VVC), and Trichomonas vaginalis (TV) is not standardized. Diagnostic approaches and appropriateness of treatment were evaluated for women with symptoms of vaginitis who were seeking care at community practice sites.

Methods: Three hundred three symptomatic women, across 8 University of Pittsburgh Medical Center-affiliated clinics, were evaluated per standard office-based practice. Read More

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http://dx.doi.org/10.1093/cid/ciaa260DOI Listing

[Literature review on studies of women who have sex with women].

Medwave 2020 Apr 17;20(3):e7884. Epub 2020 Apr 17.

Facultad de Trabajo Social y Desarrollo Humano, Universidad Autónoma de Nuevo León, Nuevo León, México. Email: ORCID: 0000-0002-1748-9303.

Women who have sex with other women are a group that has been mostly invisible from public health policies. This category includes the group of lesbians, bisexual women, heterosexual behaviour, and homosexual practices, who have sexual relations with transsexual and transgender (trans) women and trans men who have sex with women. In the absence of a Spanish literature review of a study that addresses women who have sex with other women, a narrative bibliographic review was done using the PubMed/MEDLINE, Scopus, Dialnet, and Taylor and Francis databases. Read More

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http://dx.doi.org/10.5867/medwave.2020.03.7884DOI Listing

First molecular study of Canine herpesvirus-1 in reproductive specimens of adult dogs in southeast of Iran.

Comp Immunol Microbiol Infect Dis 2020 Apr 19;71:101487. Epub 2020 Apr 19.

Department of Clinical Science, Faculty of Veterinary Medicine, Shahid Bahonar University of Kerman, Kerman, Iran.

Canine herpesvirus-1 (CHV-1) is recognized to be enzootic in the dog population with a widespread distribution. This pathogen leads to a lethal generalized illness in newborn puppies and is associated with reproductive disorders. CHV-1 should be considered as an important pathogen of neonatal death and infertility; so, it appears to pose a threat for breeding kennels. Read More

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http://dx.doi.org/10.1016/j.cimid.2020.101487DOI Listing

Sequence of Pelvic Examination Does Not Affect Patients With Baseline Vulvovaginal Syndromes: A Randomized Clinical Trial.

Female Pelvic Med Reconstr Surg 2020 Apr 21. Epub 2020 Apr 21.

Drexel Vaginitis Center, Department of Obstetrics and Gynecology, Drexel University College of Medicine, Philadelphia, PA.

Objective: The purpose of this study is to determine the optimal sequence in performing a pelvic examination to reduce discomfort in patients with baseline vaginal pain.

Methods: A randomized controlled trial of women presenting for a new appointment at the Drexel Vaginitis Center was conducted. Women were assigned to either group A, a Q-tip touch test, speculum examination, then bimanual examination, or group B, a Q-tip touch test, bimanual examination, then speculum examination. Read More

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http://dx.doi.org/10.1097/SPV.0000000000000791DOI Listing

Vaginitis in Nonpregnant Patients: ACOG Practice Bulletin Number 215.

Obstet Gynecol 2020 May;135(5):1229-1230

University of Helsinki, Finland Department of Medicine, University of British Columbia, Faculty of Medicine, Heather Pavilion East, Vancouver British Columbia, Canada.

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http://dx.doi.org/10.1097/AOG.0000000000003857DOI Listing

The Comparative Analysis of Antiviral Activity of Native and Modified Fucoidans from Brown Algae In Vitro and In Vivo.

Mar Drugs 2020 Apr 22;18(4). Epub 2020 Apr 22.

G.P. Somov Institute of Epidemiology and Microbiology, 690087 Vladivostok, Russia.

The enzymatic depolymerization of fucoidans from brown algae allowed the production of their standardized derivatives with different biological activities. This work aimed to compare the antiviral activities of native (FeF) and modified with enzyme (FeHMP) fucoidans from . The cytotoxicity and antiviral activities of the FeF and FeHMP against herpes viruses (HSV-1, HSV-2), enterovirus (ECHO-1), and human immunodeficiency virus (HIV-1) in Vero and human MT-4 cell lines were examined by methylthiazolyltetrazolium bromide (MTT) and cytopathic effect (CPE) reduction assays, respectively. Read More

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http://dx.doi.org/10.3390/md18040224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230360PMC

Mucoadhesive Chitosan Delivery System with Lyophilized Extract as a Promising Strategy for Vaginitis Treatment.

J Clin Med 2020 Apr 22;9(4). Epub 2020 Apr 22.

Department of Pharmacognosy, Faculty of Pharmacy, Poznan University of Medical Sciences, Swiecickiego 4, 60781 Poznan, Poland.

(also known as celandine) contains pharmacologically active compounds such as isoquinoline alkaloids (e.g., chelidonine, sanguinarine), flavonoids, saponins, carotenoids, and organic acids. Read More

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http://dx.doi.org/10.3390/jcm9041208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230236PMC

Fractional Co Laser Treatment of the Vulva and Vagina and the Effect of Postmenopausal Duration on Efficacy.

Lasers Surg Med 2020 Apr 23. Epub 2020 Apr 23.

Dermatology and Laser Surgery Center of New York, Yale University School of Medicine, New York, New York.

Background And Objectives: More studies are needed to assess the long-term safety profile and clinical outcomes of lasers and energy-based devices to treat the symptoms associated with vulvovaginal atrophy. This study evaluated a series of three fractional CO laser treatments to the vulva and vagina with a 1-year follow-up in a postmenopausal population.

Study Design/materials And Methods: In this prospective, self-controlled, open-label clinical study, 18 postmenopausal females with atrophic vaginitis received 3 monthly treatments to the vulva and vagina with a fractional CO laser system and 1-, 3-, 6-, and 12-month follow-up. Read More

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http://dx.doi.org/10.1002/lsm.23247DOI Listing

Use of Probiotics in Intravaginal Sponges in Sheep: A Pilot Study.

Animals (Basel) 2020 Apr 20;10(4). Epub 2020 Apr 20.

Research Group Microbiological agents associated with animal reproduction (PROVAGINBIO), Department of Animal Production and Health, Veterinary Public Health and Food Science and Technology (PASAPTA) Facultad de Veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, 46113 Valencia, Spain.

Sheep estrous synchronization is mainly based on progestagen-impregnated sponges which could cause vaginitis. Several species of Lactobacillus used as probiotics are commonly used in the treatment or prevention of urogenital infections in humans. However, no studies have been performed to analyze the potential use of probiotics to prevent urogenital infections in sheep. Read More

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http://dx.doi.org/10.3390/ani10040719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222760PMC

Characteristics of urogenital infections in a diverse patient sample from the United States; results from the Aptima Mycoplasma genitalium Evaluation Study (AMES).

J Clin Microbiol 2020 Apr 22. Epub 2020 Apr 22.

Hologic, Inc. 20120 Genetic Center Dr, San Diego CA 92121.

Data from a large prospective multicenter clinical validation study of a nucleic acid amplification diagnostic test for were analyzed to describe the prevalence of infection, risk factors, and disease associations in female and male patients seeking care in diverse geographic regions of the United States. Among 1737 female and 1563 male participants, overall prevalence was ∼10%, and was significantly higher in persons ages 15-24 compared to ages 35-39 (female: 19.8% vs. Read More

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http://dx.doi.org/10.1128/JCM.00165-20DOI Listing

The Effect of Neural Therapy on Long-Term Postoperative Discomforts after Bilateral Tubal Ligation.

Complement Med Res 2020 Apr 21:1-5. Epub 2020 Apr 21.

Physical Therapy and Rehab Private Naturel Health Clinic, Istanbul, Turkey.

Background: In this study, we aimed to assess the effect of neural therapy in the prevention of post-tubal syndrome, which is the combination of dysmenorrhea, bloating, dyspareunia, heavy menstrual bleeding, chronic vaginitis, and cystitis, after elective bilateral tubal ligation with modified Pomeroy technique.

Material And Methods: In total, 113 patients who have undergone bilateral tubal ligation with modified Pomeroy technique between January 2016 and December 2018 in our clinic have been included. Postoperatively, patients were divided into two groups. Read More

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http://dx.doi.org/10.1159/000507108DOI Listing

Anidulafungin treatment for fluconazole-resistant vaginitis with cross-resistance to azoles: a case report.

J Obstet Gynaecol 2020 Apr 21:1-2. Epub 2020 Apr 21.

Department of Infectious Diseases and Clinical Microbiology, Ege University Faculty of Medicine, Izmir, Turkey.

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http://dx.doi.org/10.1080/01443615.2020.1732893DOI Listing

Prepubertal and Adolescent Vulvovaginitis: What to Do When a Girl Reports Vaginal Discharge.

Pediatr Ann 2020 Apr;49(4):e170-e175

Vaginitis presents with vaginal discharge, odor, pruritis, and/or discomfort and affects up to 75% of girls and women over the course of their lifetimes, with most women experiencing their first episode during adolescence. Given the prevalence of this disorder, this article aims to provide an overview of vaginitis for the general pediatrician. We start with prepubertal etiologies of vaginitis, then discuss pubertal and normal physiologic discharge, and then focus on the most common etiologies of adolescent vulvovaginitis. Read More

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http://dx.doi.org/10.3928/19382359-20200317-01DOI Listing

Systematic analysis of bacteriostatic mechanism of flavonoids using transcriptome and its therapeutic effect on vaginitis.

Aging (Albany NY) 2020 04 9;12(7):6292-6305. Epub 2020 Apr 9.

State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Fujian Agriculture and Forestry University, Fuzhou, China.

The flavonoids in L. have been used in traditional medicine due to its anti-inflammatory and antibacterial properties. However, the specific mechanism of its antibacterial effect, and the potential therapeutic effect on vaginitis have not been well explained. Read More

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http://dx.doi.org/10.18632/aging.103024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185132PMC

[Analysis of homology and drug sensitivity of vaginal isolates of 10 patients with recurrent vulvovaginal candidiasis in recurrent episodes].

Zhonghua Fu Chan Ke Za Zhi 2020 Mar;55(3):177-182

Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China.

To detect karyotype homology of vaginal isolates from patients with recurrent vulvovaginal candidiasis (RVVC) in recurrent episodes, and to discuss changes of susceptibility of Candida strains to antifungal drugs with clinical progress. s Ten patients were recruited from Beijing Obstetrics and Gynecology Hospital, Capital Medical University from September 2018 to June 2019, who were firstly diagnosed with RVVC. Vaginal discharges were collected before first treatment and after first relapse. Read More

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http://dx.doi.org/10.3760/cma.j.cn112141-20191210-00665DOI Listing

Screening for Bacterial Vaginosis in Pregnant Persons to Prevent Preterm Delivery: US Preventive Services Task Force Recommendation Statement.

JAMA 2020 04;323(13):1286-1292

Tufts University School of Medicine, Boston, Massachusetts.

Importance: Bacterial vaginosis is common and is caused by a disruption of the microbiological environment in the lower genital tract. In the US, reported prevalence of bacterial vaginosis among pregnant women ranges from 5.8% to 19. Read More

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http://dx.doi.org/10.1001/jama.2020.2684DOI Listing

Screening for Bacterial Vaginosis in Pregnant Adolescents and Women to Prevent Preterm Delivery: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.

JAMA 2020 04;323(13):1293-1309

RTI International-University of North Carolina at Chapel Hill Evidence-based Practice Center.

Importance: Preterm delivery results in adverse outcomes; identifying and treating bacterial vaginosis may reduce its occurrence.

Objective: To update the evidence on screening and treatment of asymptomatic bacterial vaginosis in pregnancy for the US Preventive Services Task Force.

Data Sources: MEDLINE, Cochrane Library, and trial registries through May 29, 2019; bibliographies from retrieved articles, experts, and surveillance of the literature through December 31, 2019. Read More

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http://dx.doi.org/10.1001/jama.2020.0233DOI Listing

Screening for Bacterial Vaginosis During Pregnancy.

Authors:
Jill Jin

JAMA 2020 04;323(13):1324

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http://dx.doi.org/10.1001/jama.2020.3690DOI Listing

USPSTF 2020 Recommendations on Screening for Asymptomatic Bacterial Vaginosis in Pregnancy.

JAMA 2020 04;323(13):1253-1255

Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla.

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http://dx.doi.org/10.1001/jama.2019.22311DOI Listing

Vaginal pH and microbiota during fluconazole maintenance treatment for recurrent vulvovaginal candidosis (RVVC).

Diagn Microbiol Infect Dis 2020 Jun 14;97(2):115024. Epub 2020 Feb 14.

Femicare Clinical Research for Women, Tienen, Belgium.

Background: It is commonly stated that Candida in the vagina prefers a low pH to develop infection. However, mixed infections of Candida with bacterial vaginosis (BV) and aerobic vaginitis (AV) are rather common and may challenge the rule that Candida should only be looked for in low vaginal pH settings. In this study we tested whether the vaginal pH in acute vaginal candidosis is lower than in women successfully treated to prevent Candida recurrences. Read More

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http://dx.doi.org/10.1016/j.diagmicrobio.2020.115024DOI Listing

Differential Expression of Local Immune Response Genes in the Vagina: Implication for the Diagnosis of Vaginal Infections.

Bull Exp Biol Med 2020 Mar 4;168(5):646-650. Epub 2020 Apr 4.

D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Saint Petersburg, Russia.

Transcription profiles of genes of local immune response were determined in the vagina of women with bacterial vaginosis, aerobic vaginitis, and vulvovaginal candidosis for detection of the most specific immune markers for these vaginal infections. Laboratory diagnosis of the vaginal infections was performed microscopically; the inflammatory reaction in the vagina (leukorrhea) was defined as the presence of >10 white blood cells per field of view. Transcription profiles of IL1b, IL10, IL18, TNFα, TLR4, GATA3, and CD68 were determined using reverse-transcription quantitative real-time PCR. Read More

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http://dx.doi.org/10.1007/s10517-020-04771-3DOI Listing

Mechanisms of Pathogenic Species to Evade the Host Complement Attack.

Front Cell Infect Microbiol 2020 12;10:94. Epub 2020 Mar 12.

Department of Microbiology, University of Szeged, Szeged, Hungary.

species are common colonizers of the human skin, vagina, and the gut. As human commensals, species do not cause any notable damage in healthy individuals; however, in certain conditions they can initiate a wide range of diseases such as chronic disseminated candidiasis, endocarditis, vaginitis, meningitis, and endophthalmitis. The incidence of caused infections has increased worldwide, with mortality rates exceeding 70% in certain patient populations. Read More

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http://dx.doi.org/10.3389/fcimb.2020.00094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082757PMC

Unexpected association between increased levels of ambient carbon monoxide and reduced daily outpatient visits for vaginitis: A hospital-based study.

Sci Total Environ 2020 Jun 13;723:137923. Epub 2020 Mar 13.

Department of Epidemiology, College of Preventive Medicine, Army Medical University (Third Military Medical University), Chongqing, China. Electronic address:

Carbon monoxide (CO) is a well-known "toxic gas". It represents a toxic inhalation hazard at high concentration and is commonly found in polluted air. However, a series of recent studies have suggested that low concentration of CO can also produce protective functions. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2020.137923DOI Listing

Prevalence of Mycoplasma genitalium infection in women with bacterial vaginosis.

BMC Womens Health 2020 Mar 26;20(1):62. Epub 2020 Mar 26.

SpeeDx Pty. Ltd., Sydney, Australia.

Background: Bacterial vaginosis (BV) is a common condition in reproductive-age women and is known to be positively associated with risk of acquisition of sexually transmitted infections (STI) such as chlamydia and gonorrhea. Mycoplasma genitalium is an emerging STI that has been linked to increased risk of pelvic inflammatory disease, adverse pregnancy outcomes and infertility. In the present study we sought to examine whether women diagnosed with symptomatic BV were at increased risk of having concurrent infection with Mycoplasma genitalium. Read More

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http://dx.doi.org/10.1186/s12905-020-00926-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099815PMC

Low prevalence of antifungal resistant in the complex causing vulvovaginal candidiasis.

Heliyon 2020 Mar 19;6(3):e03619. Epub 2020 Mar 19.

Department of Gynecology, Shahid Akbar Abadi Hospital, Iran University of Medical Sciences, Tehran, Iran.

The (.) complex includes , , and , with the last mentioned as an important emerging agent of vulvovaginal candidiasis (VVC). The aim of the study was to identify and and assess their drug susceptibility in vaginitis. Read More

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http://dx.doi.org/10.1016/j.heliyon.2020.e03619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090347PMC

[MORAXELLA OSLOENSIS BACTEREMIA WITH PNEUMONIA: FIRST REPORTED CASE IN ISRAEL].

Harefuah 2020 Mar;159(3):163-165

Galilee Medical Center, Department of Internal Medicine "D", Nahariya.

Introduction: Community acquired pneumonia (CAP), an acute infection of the pulmonary parenchyma acquired in the community, is generally treated in an outpatient setting and involves different etiological agents. In the adult community, the most common pathogen in the disease is Streptococcus pneumonia, though other multiple etiological agents (atypical) have been involved, including Mycoplasma pneumoniae, Chlamydophila pneumoniae, and Legionella pneumophila. The genus Moraxella consists of aerobic, oxidase-positive gram-negative coccobacilli. Read More

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The effect of iron on TvCP2: a cysteine proteinase found in vaginal secretions of trichomoniasis patients.

Parasitology 2020 Jun 16;147(7):760-774. Epub 2020 Mar 16.

Departamento de Infectómica y Patogénesis Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV-IPN), CP 07360, Mexico City, Mexico.

Trichomonas vaginalis (Tv) induces host cell damage through cysteine proteinases (CPs) modulated by iron. An immunoproteomic analysis showed that trichomoniasis patient sera recognize various CPs, also some of them are present in vaginal washes (VWs). Thus, the goal of this work was to determine whether TvCP2 is expressed during infection and to assess the effect of iron on TvCP2 expression, localization and contribution to in vitro cellular damage. Read More

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http://dx.doi.org/10.1017/S0031182020000438DOI Listing

Bacterial vaginosis and antibacterial susceptibility pattern of asymptomatic urinary tract infection in pregnant women at a tertiary care hospital, Visakhaptn, India.

Iran J Microbiol 2019 Dec;11(6):488-495

Department of Community Medicine, GITAM Institute of Medical Sciences and Research, Visakhapatnam, Andhra Pradesh, India.

Background And Objectives: The association between bacterial vaginosis and urinary tract infection (UTI) in pregnant women is at a greater risk comparatively than patients with bacterial vaginosis or UTI. Bacterial vaginosis and asymptomatic UTI both pose risk for mother and fetus. Early diagnosis and treatment can save the life of both. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048967PMC
December 2019

Gynecological Disorders in Patients with Non-celiac Wheat Sensitivity.

Dig Dis Sci 2020 Mar 7. Epub 2020 Mar 7.

Internal Medicine Unit, Department of Health Promotion Sciences, Maternal and Infant Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90129, Palermo, Italy.

Background: Non-celiac wheat sensitivity (NCWS) most frequently presents clinically with irritable bowel syndrome (IBS)-like symptoms, although many extra-intestinal manifestations have also been attributed to it. No studies to date have evaluated the presence and frequency of gynecological symptoms in NCWS.

Aim: To evaluate the frequency of gynecological disorders in patients with NCWS. Read More

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http://dx.doi.org/10.1007/s10620-020-06184-8DOI Listing

Syndromic management of sexually transmitted infections: A critical appraisal and the road ahead.

Natl Med J India 2019 May-Jun;32(3):147-152

Department of Dermatology and Venereology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.

The syndromic approach has been the cornerstone of management of sexually transmitted infections (STIs) in developing countries. This strategy has had a considerable impact in decreasing the burden of STI in society. It offers the advantages of treating the infection at the first visit itself, reducing the risk of complications, non-reliance on laboratory diagnostics, and easy integration into the primary healthcare system. Read More

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http://dx.doi.org/10.4103/0970-258X.278691DOI Listing

Vulvovaginal Candidiasis: A Current Understanding and Burning Questions.

J Fungi (Basel) 2020 Feb 25;6(1). Epub 2020 Feb 25.

Department of Clinical Pharmacy and Translational Science, College of Pharmacy, University of Tennessee Health Science Center, Memphis, TN 38163, USA.

, along with other closely related species, are the primary causative agents of vulvovaginal candidiasis (VVC)-a multifactorial infectious disease of the lower female reproductive tract resulting in pathologic inflammation. Unlike other forms of candidiasis, VVC is a disease of immunocompetent and otherwise healthy women, most predominant during their child-bearing years. While VVC is non-lethal, its high global incidence and profound negative impact on quality-of-life necessitates further understanding of the host and fungal factors that drive disease pathogenesis. Read More

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http://dx.doi.org/10.3390/jof6010027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151053PMC
February 2020

Commensal and virulent Escherichia coli strains of vaginal origin are reservoirs of resistance cassettes in class 1 integrons.

J Infect Dev Ctries 2020 Jan 31;14(1):48-58. Epub 2020 Jan 31.

Hospital Juárez de México , Ciudad de México, México.

Introduction: Antimicrobial resistance in Escherichia coli, one of the causal agents of aerobic vaginitis, leads to the persistence of the infection. The investigation of integrons acquires relevance, since they are elements that are responsible for the acquisition of resistance to antibiotics. The aim of this work was to describe the structural diversity of class 1 integrons in virulent and commensal strains of E. Read More

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http://dx.doi.org/10.3855/jidc.11940DOI Listing
January 2020

The Chinese herbal prescription JZ-1 induces autophagy to protect against herpes simplex Virus-2 in human vaginal epithelial cells by inhibiting the PI3K/Akt/mTOR pathway.

J Ethnopharmacol 2020 May 20;254:112611. Epub 2020 Feb 20.

Institute of Integrated Traditional Chinese and Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China; Department of Integrated Traditional Chinese and Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. Electronic address:

Ethnophamacological Relevance: The Chinese herbal prescription JieZe-1 (JZ-1) is based on the modification of Yihuang Tang, which was first described in Fu Qingzhu Nvke by the famous Qing Dynasty doctor Shan Fu as a treatment for leukorrheal diseases. As an in-hospital preparation, JZ-1 has been used in Tongji Hospital for many years to treat various infectious diseases of the lower female genital tract, including cervicitis, vaginitis, genital herpes and condyloma acuminatum. Our previous studies have shown that JZ-1 has curative effects on Candida albicans, Trichomonas vaginalis and Ureaplasma urealyticum infections. Read More

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http://dx.doi.org/10.1016/j.jep.2020.112611DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126429PMC

Is genital tract infection related to tubal diseases in infertile Vietnamese women?

J Infect Dev Ctries 2019 10 31;13(10):906-913. Epub 2019 Oct 31.

Competence Centre on Health Technologies, Tartu, Estonia.

Introduction: The goal of this study was to identify the profile of genital tract infections and their relationship with clinical and demographic parameters as well as tubal diseases among infertile women in Vietnam.

Methodology: In this cross-sectional descriptive study, we enrolled 597 women undergoing infertility treatment at the Center for Reproductive Endocrinology and Infertility, Hue University Hospital, Vietnam. All of the study participants were interviewed and examined by a gynecologist. Read More

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http://dx.doi.org/10.3855/jidc.11632DOI Listing
October 2019

PCR Detection and Sequencing of Trichomonas vaginalis in Women with Suspected Vaginitis in the southwestern Iran.

Infect Disord Drug Targets 2020 Feb 18. Epub 2020 Feb 18.

Department of Obstetrics & Gynecology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz. Iran.

Introduction: The human being is considered a natural host for Trichomonas vaginalis (T. vaginalis), which causes trichomoniasis, the most frequent non-viral sexually transmitted infectious disease in the world. The current study aimed to evaluate the prevalence and sequencing of T. Read More

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http://dx.doi.org/10.2174/1871526520666200219110430DOI Listing
February 2020

Fractionated CO2 Laser as Therapy in Recalcitrant Lichen Sclerosus.

J Low Genit Tract Dis 2020 Apr;24(2):225-228

Department of Obstetrics and Gynecology, Drexel University College of Medicine, Philadelphia, PA.

Objectives: The aim of this study was to evaluate the efficacy of the fractionated CO2 laser in treating recalcitrant lichen sclerosus (LS).

Materials And Methods: The study population was 40 women diagnosed with LS who were symptomatic despite medical treatment. Patients had at least 2 or more laser sessions with a 2-month follow-up visit at the Drexel Vaginitis Center. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000512DOI Listing

Fournier Gangrene in Men and Women: Appearance on CT, Ultrasound, and MRI and What the Surgeon Wants to Know.

Can Assoc Radiol J 2020 Feb 28;71(1):30-39. Epub 2020 Jan 28.

Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.

Fournier gangrene (FG) is a genitourinary necrotizing fasciitis that can be lethal if not promptly diagnosed and surgically debrided. The diagnosis is often made by physical examination paired with an appropriate clinical suspicion and supporting laboratory values. Imaging, particularly computed tomography (CT), plays a role in delineating involved fascial planes for operative debridement and occasionally in diagnosing FG. Read More

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http://dx.doi.org/10.1177/0846537119888396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047600PMC
February 2020
0.584 Impact Factor

[Evaluation of Microscopic Examination, Culture and Polymerase Chain Reaction Tests in the Diagnosis of Trichomonas vaginalis Infection].

Mikrobiyol Bul 2020 Jan;54(1):135-143

Akdeniz University Faculty of Medicine, Department of Medical Microbiology, Antalya, Turkey.

Sexually transmitted infections (STIs) are important as a public health problem all over the world. There are some difficulties in prevention and control programs of STIs due to clinical and laboratory diagnostic problems.The most common STIs are Chlamydia trachomatis infections, trichomoniasis and gonorrhea. Read More

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http://dx.doi.org/10.5578/mb.68828DOI Listing
January 2020

Vaginal Microbiota and Mucosal Immune Markers in Women With Vulvovaginal Discomfort.

Sex Transm Dis 2020 Apr;47(4):269-274

Vaccine and Infectious Diseases Division, Fred Hutchinson Research Center, Seattle, WA.

Background: Up to 30% of women with vaginal symptoms are not assigned a diagnosis after standard diagnostic assessment.

Methods: We compared premenopausal women with idiopathic vaginitis (IV) or vulvodynia (VVD) to healthy controls. Microbiota were characterized using rRNA sequencing. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000001143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071966PMC