13,141 results match your criteria Vaginitis


Successful mast-cell-targeted treatment of chronic dyspareunia, vaginitis, and dysfunctional uterine bleeding.

J Obstet Gynaecol 2019 Apr 9:1-6. Epub 2019 Apr 9.

c HealthPartners North Suburban Family Physicians , Roseville , MN , USA.

Dyspareunia, vaginitis and dysfunctional uterine bleeding (DUB) are common problems which, despite their polygenicity, commonly appear idiopathic and treatment-refractory. Mast cell (MC) activation syndrome (MCAS) is a newly-recognised, prevalent, chronic multisystem polymorbidity of general themes of inflammation ± allergic-type phenomena ± aberrant growth/development in assorted tissues. MCs produce significant quantities of heparin, too. Read More

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http://dx.doi.org/10.1080/01443615.2018.1550475DOI Listing
April 2019
2 Reads

Prenatal maternal vaginal inflammation increases anxiety and alters HPA axis signalling in adult male mice.

Int J Dev Neurosci 2019 Apr 4;75:27-35. Epub 2019 Apr 4.

Department of Obstetrics, Baoan Maternal and Child Health Hospital, Jinan University, Shenzhen 518100, China; Shenzhen Key Laboratory of Birth Defects in Baoan Maternal and Child Health Care Affiliated Hospital in Jinan University, Shenzhen, China. Electronic address:

Background: Maternal infection during pregnancy is known to adversely affect foetal development, but previous studies have rarely investigated the impact of gynaecological diseases during pregnancy on offspring during adulthood. Vaginitis is one of the most prevalent gynaecological diseases during pregnancy.

Methods: The effect of maternal vaginal inflammation on offspring was simulated by inducing maternal vaginal infection. Read More

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http://dx.doi.org/10.1016/j.ijdevneu.2019.04.001DOI Listing
April 2019
2 Reads

Sexually Transmitted Diseases in the Emergency Department.

Emerg Med Clin North Am 2019 May;37(2):165-192

Prisma Health, University of South Carolina School of Medicine Greenville, 701 Grove Road, Greenville, SC 29605, USA. Electronic address:

Sexually transmitted diseases (STDs) continue to be underrecognized leading to devastating health and economic consequences. Emergency clinicians play an important role in diagnosing and managing STDs and in improving health care outcomes for both the patient and their partners. In addition, antibiotic resistance and emerging infections continue to challenge providers in clinical practice. Read More

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http://dx.doi.org/10.1016/j.emc.2019.01.001DOI Listing
May 2019
1 Read

Current patient perspectives of vulvovaginal candidiasis: incidence, symptoms, management and post-treatment outcomes.

BMC Womens Health 2019 Mar 29;19(1):48. Epub 2019 Mar 29.

Center of Excellence in Oral and Craniofacial Biology, School of Dentistry, Louisiana State University Health Sciences Center, New Orleans, LA, USA.

Background: Vulvovaginal candidiasis (VVC) is a common infection affecting women worldwide. Reports of patterns/risk factors/trends for episodic/recurrent VVC (RVVC) are largely outdated. The purpose of this study was to obtain current patient perspectives of several aspects of VVC/RVVC. Read More

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http://dx.doi.org/10.1186/s12905-019-0748-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441174PMC
March 2019
3 Reads

Brief versus Thong Hygiene in Obstetrics and Gynecology (B-THONG): A survey study.

J Obstet Gynaecol Res 2019 Mar 27. Epub 2019 Mar 27.

Department of Obstetrics and Gynecology, University of Colorado School of Medicine, Aurora, Colorado, USA.

Aim: The aim of this study was to evaluate if thong use is associated with a higher report of urogenital infections, including urinary tract infections, yeast vaginitis and bacterial vaginosis.

Methods: A cross-sectional survey regarding underwear preferences and infectious history was designed and distributed to women via a crowdsourcing service. All survey questions related to the last 12 months. Read More

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http://dx.doi.org/10.1111/jog.13958DOI Listing
March 2019
1 Read

ASSOCIATION OF SEXUALLY TRANSMITTED DISEASES WITH CERVICAL ECTOPY: A SYSTEMATIC REVIEW.

Sex Transm Dis 2019 Feb 27. Epub 2019 Feb 27.

Rio de Janeiro State University, Adjunct professor, Gynecology department.

Objective: The aim of this study was to review the available literature to explore evidence indicating an association between cervical ectopy and sexually transmitted diseases, which could help in the decision to treat or not to treat this condition.

Methods: A review of the literature was conducted using the PubMed, EMBASE and clinicaltrials.gov databases on ectopy of the cervix using the terms 'ectopy OR ectropium AND cervix' filtered only by language, without limit of date. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000992DOI Listing
February 2019
4 Reads

Evaluation of the vaginal microbiome in clinical diagnosis and management of vaginal infectious diseases.

Chin Med J (Engl) 2019 Mar 19. Epub 2019 Mar 19.

Department of Microecological Laboratory, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China.

Objective: The Vaginal Microecology Evaluation System (VMES) is a technical and economically feasible tool to assess the vaginal microbiomes of gynecological outpatients. The aim of this review was to introduce knowledge on the potential changes that can occur in the vaginal microbiome and how to use the Evaluation System to diagnose and manage a broad range of vaginal infections.

Data Sources: This review was based on data in articles published in PubMed up to December 10, 2018, with the following keywords: "Vaginal microecosystem", "vaginal microbiome", "vaginal microbiota", and "vaginal flora". Read More

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http://dx.doi.org/10.1097/CM9.0000000000000211DOI Listing
March 2019
1 Read

Intravaginal Delivery of (Bong.) Ruhland Fraction Based on a Nanoemulsion System Applied to Vulvovaginal Candidiasis Treatment.

J Biomed Nanotechnol 2019 May;15(5):1072-1089

In this study, was evaluated the chemical composition of a fraction from extract and its antimicrobial potential unloaded (Fr3) and loaded (F9Fr3) into a nanoemulsion (F9) composed of cholesterol as the oil phase (10%), polyoxyethylene 20-cetyl ether and soy phosphatidylcholine (2:1) as surfactant (20%), and a solution of phosphate buffer (pH 7.4) plus chitosan polymer dispersion (0.25%) as the aqueous phase (70%) to use for VVC treatment. Read More

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http://dx.doi.org/10.1166/jbn.2019.2750DOI Listing

Emerging role for Ureaplasma parvum serovar 3: Active infection in women with silent high-risk human papillomavirus and in women with idiopathic infertility.

J Cell Physiol 2019 Mar 18. Epub 2019 Mar 18.

Institute for Maternal and Child Health-IRCCS "Burlo Garofolo", Trieste, Italy.

Recently, there are controversial opinions on the presence of Mycoplasmas/Ureaplasmas as colonizers or pathogens, and on the use of a targeted therapy. This study aimed to characterize Mycoplasmas/Ureaplasmas infections in reproductive age women, including the acquisition of sexually transmitted (ST) pathogens and poor birth outcomes. A total of 646 healthy Italian women fulfilled the inclusion criteria including 521 infertile women, 65 pregnant women, and 60 fertile women with identified risk factors and symptomatic for vaginitis/cervicitis. Read More

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http://dx.doi.org/10.1002/jcp.28423DOI Listing
March 2019
4 Reads

Case Report: Efficient and Cost-Effective Diagnosis of Vaginitis.

Am Fam Physician 2019 Mar;99(6):344

Rockville, MD, USA.

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March 2019
1 Read

Bacterial Vaginosis and Desquamative Inflammatory Vaginitis. Reply.

N Engl J Med 2019 03;380(11):1089

University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1056/NEJMc1900134DOI Listing
March 2019
6 Reads

Bacterial Vaginosis and Desquamative Inflammatory Vaginitis.

N Engl J Med 2019 03;380(11):1088-1089

Positivo University, Curitiba, Brazil

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http://dx.doi.org/10.1056/NEJMc1900134DOI Listing
March 2019
2 Reads

Comparison of the effect of hyaluronic acid and estrogen on atrophic vaginitis in menopausal women: A systematic review.

Post Reprod Health 2019 Feb 24:2053369119830818. Epub 2019 Feb 24.

3 Social Determinants of Health Research Center, Department of Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran.

This systematic review was conducted to compare the effectiveness of hyaluronic acid and estrogen on symptoms of atrophic vaginitis (primary outcomes) and corresponding side effects (secondary outcome). We reviewed all parallel clinical trials, systematically, to compare the effectiveness of hyaluronic acid and estrogen on atrophic vaginitis. We searched Pubmed, Embase, Web of Sciences, Cochrane library, Scopus, Google Scholar, Magiran, Scientific Information Database (Iran) and Iranian Registry of Clinical Trials, from inception to July 2018 and the reference lists of retrieved articles. Read More

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http://dx.doi.org/10.1177/2053369119830818DOI Listing
February 2019
9 Reads

PRISM study: Comparison of a nystatin-neomycin-polymyxin B combination with miconazole for the empirical treatment of infectious vaginitis.

Med Mal Infect 2019 May 18;49(3):194-201. Epub 2019 Feb 18.

Laboratoire Innotech International, Groupe Innothera, 22, avenue Aristide-Briand, 94110 Arcueil, France.

Objective: An empirical treatment of infectious vaginitis is justified because of its multiple etiologies, the frequent uncertainty of clinical diagnosis and limits of microbiological analysis. Our aim was to comparatively investigate nystatin-neomycin-polymyxin B combination (NNP, Polygynax) and miconazole.

Patients And Methods: In this European multicenter, double-blind PRISM trial, participating women presenting with infectious vaginitis were randomized to receive one vaginal capsule containing either NNP for 12 days or miconazole for 3 days followed by 9 days of placebo. Read More

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http://dx.doi.org/10.1016/j.medmal.2019.01.011DOI Listing

The effect of vitamin D and E vaginal suppositories on tamoxifen-induced vaginal atrophy in women with breast cancer.

Support Care Cancer 2019 Apr 7;27(4):1325-1334. Epub 2019 Feb 7.

Department of Midwifery, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran.

Purpose: Vaginal atrophy is one of the most common side effects of using tamoxifen in women with breast cancer. Hormone therapy for vaginal atrophy is prohibited in these women. The present study was conducted to investigate the effect of vitamin D and E vaginal suppositories on vaginal atrophy in women with breast cancer receiving tamoxifen. Read More

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http://dx.doi.org/10.1007/s00520-019-04684-6DOI Listing
April 2019
1 Read

A Study of Pap Smears in HIV-Positive and HIV-Negative Women from a Tertiary Care Center in South India.

Acta Cytol 2019 5;63(1):50-55. Epub 2019 Feb 5.

Department of Pathology, Kasturba Medical College, Manipal Academy of Higher Education, Mangalore, India.

Objectives: The aim of this work was to study the spectrum of epithelial abnormalities on Pap smears of HIV-positive women categorized as per the Bethesda System of Reporting Cervical Cytology, to correlate them with CD4 lymphocyte counts, and to compare them with the spectrum of abnormalities seen in a HIV-negative control group. Study Design and Methodology: The present study was a 6-year retrospective study conducted in the Department of Pathology at Kasturba Medical College, Mangalore, which included 150 Pap smears from HIV-positive and HIV-negative women, respectively. The Pap-stained slides of the cases were retrieved and studied. Read More

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http://dx.doi.org/10.1159/000496211DOI Listing
March 2019
14 Reads

Accuracy of the BD MAX™ vaginal panel in the diagnosis of infectious vaginitis.

Eur J Clin Microbiol Infect Dis 2019 May 26;38(5):877-882. Epub 2019 Jan 26.

Servicio de Microbiología, Hospital Universitario de Álava, Instituto de Investigación Biosanitaria, BioAraba, Osakidetza-Servicio Vasco de Salud. c/ Francisco Leandro de Viana, s/n., 01009, Vitoria-Gasteiz, Álava, Spain.

The aim of this study was to evaluate the BD MAX™ vaginal panel in the diagnosis of bacterial vaginosis (BV), vulvovaginal candidiasis (VVC), and trichomoniasis by comparing it with conventional methods: (i) combination of Hay criteria and presence of clue cells with predominant growth of Gardnerella vaginalis, (ii) yeast culture, and (iii) combination of culture, wet mount microscopic examination, and an alternative molecular assay. One thousand vaginal samples of women ≥ 14 years were analyzed; 5% of the samples belonged to pregnant women. 19. Read More

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http://dx.doi.org/10.1007/s10096-019-03480-8DOI Listing
May 2019
4 Reads

Prevalence, antimicrobial susceptibility, serotyping and virulence genes screening of strains at a tertiary care hospital in Tehran, Iran.

Iran J Microbiol 2018 Oct;10(5):307-313

Food Microbiology Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Background And Objectives: is the etiological agent of listeriosis, a highly fatal infection which causes miscarriage or stillbirth in pregnant women. The objective of this study was to detect the prevalence, serotypes, antimicrobial susceptibility and virulence factors of isolated from pregnant women with vaginitis at a tertiary care hospital in Tehran, Iran.

Materials And Methods: During September 2015 to February 2017, a total of 400 vaginal swabs were collected from pregnant women. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340003PMC
October 2018
3 Reads

Disorders of vulva and vagina in children and adolescent.

Authors:
Hana Kosová

Cas Lek Cesk 2018 Dec;157(7):354-357

Disorders of vulva and vagina are the most common problem in childhood in gynecological practice. As child is not the little adult, as young girl is not little woman. Childhood is characterized by changing hormone levels, which influenced hormone-dependent tissues. Read More

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December 2018
3 Reads

Innate immune components affect growth and virulence traits of bacterial-vaginosis-associated and non-bacterial-vaginosis-associated Gardnerella vaginalis strains similarly.

Pathog Dis 2018 12 1;76(9). Epub 2018 Dec 1.

Centre of Biological Engineering (CEB), Laboratory of Research in Biofilms Rosário Oliveira (LIBRO), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.

Mucosal surfaces of the female reproductive tract contain a variety of antimicrobial components that provide the first line of defense against bacteria involved in the development of bacterial vaginosis (BV). Microbiological analysis of BV has shown Gardnerella vaginalis to be a prominent species in BV development. However, G. Read More

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http://dx.doi.org/10.1093/femspd/fty089DOI Listing
December 2018
2 Reads

Menopause hormone therapy: latest developments and clinical practice.

Authors:
Tomas Fait

Drugs Context 2019 2;8:212551. Epub 2019 Jan 2.

Department of Obstetrics and Gynecology, Faculty Hospital Motol, 2nd Faculty of Medicine, Charles University, Prague, Czech Republic.

Menopause hormone therapy (MHT) is the most efficient treatment for symptoms of acute climacteric syndrome and for efficient prevention of long-term estrogen deficiency. Vaginal administration of low doses of estrogen is a therapy of choice for treatment and prevention of urogenital atrophy and its consequences. Systemic treatment may include estrogen, but an equally efficient alternative is tibolone. Read More

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http://dx.doi.org/10.7573/dic.212551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317580PMC
January 2019
2 Reads

Enhanced antifungal activity of bovine lactoferrin-producing probiotic Lactobacillus casei in the murine model of vulvovaginal candidiasis.

BMC Microbiol 2019 Jan 8;19(1). Epub 2019 Jan 8.

Department of Obstetric & Gynecologic, West China Second University Hospital, Sichuan University, NO. 17.3rd Section, Renmin South Road, Chengdu, Sichuan, 610041, China.

Background: Vulvovaginal candidiasis (VVC) is a common vaginitis caused by Candida species,a frequently recurring condition. Fungal azole-resistant strains with azole-resistance have developed for long and wide explosion to the first-line antifungal azole agent. Bovine lactoferrin (BLF) is a protein from transferrin family secreted by the bovine mammary tissue. Read More

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https://bmcmicrobiol.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12866-018-1370-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325727PMC
January 2019
20 Reads

The antiviral activity of arbidol hydrochloride against herpes simplex virus type II (HSV-2) in a mouse model of vaginitis.

Int Immunopharmacol 2019 Mar 3;68:58-67. Epub 2019 Jan 3.

State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, PR China; Faculty of Chinese Medicine, Macau University of Science and Technology, Taipa, Macau SAR, PR China. Electronic address:

Objective: HSV-2 infection has increased significantly in recent years, which is closely associated with cervical cancer and HIV infection. The lack of success in vaccine development and the emergence of drug resistance to commonly used drugs emphasize the urgent need for alternative antivirals against HSV-2 infection. Arbidol (ARB) has been demonstrated to be a broad spectrum antiviral drug that exhibits immunomodulatory properties that affect the HSV-2 life cycle. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15675769183074
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http://dx.doi.org/10.1016/j.intimp.2018.09.043DOI Listing
March 2019
15 Reads

Prevalence of Infectious Organisms Observed in Cervical Smears Between 1997-2014 at Mubarak Al-Kabeer Hospital, Kuwait.

Sultan Qaboos Univ Med J 2018 Aug 19;18(3):e324-e328. Epub 2018 Dec 19.

Department of Pathology, Faculty of Medicine, Kuwait University, Kuwait.

Objectives: This study aimed to examine gynaecological infectious agents observed in conventional and modified Papanicolaou cervical smears (CS) at a tertiary care hospital in Kuwait.

Methods: This retrospective study analysed 121,443 satisfactory CS samples collected between 1997-2014 at the Mubarak Al-Kabeer Hospital, Kuwait. Conventional CS samples were obtained between 1997-2005, while modified CS were obtained between 2006-2014 following the introduction of ThinPrep testing (Hologic Corp. Read More

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http://dx.doi.org/10.18295/squmj.2018.18.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307630PMC
August 2018
3 Reads

Vaginal microbiome variances in sample groups categorized by clinical criteria of bacterial vaginosis.

BMC Genomics 2018 Dec 31;19(Suppl 10):876. Epub 2018 Dec 31.

Department of Medicine, MacKay Medical College, New Taipei City, Taiwan.

Background: One of the most common and recurrent vaginal infections is bacterial vaginosis (BV). The diagnosis is based on changes to the "normal" vaginal microbiome; however, the normal microbiome appears to differ according to reproductive status and ethnicity, and even among individuals within these groups. The Amsel criteria and Nugent score test are widely used for diagnosing BV; however, these tests are based on different criteria, and so may indicate distinct changes in the vaginal microbial community. Read More

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http://dx.doi.org/10.1186/s12864-018-5284-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311936PMC
December 2018
4 Reads

Progesterone effects on vaginal cytokines in women with a history of preterm birth.

PLoS One 2018 31;13(12):e0209346. Epub 2018 Dec 31.

Department of Obstetrics & Gynecology and Reproductive Medicine, Stony Brook Medicine, Stony Brook, NY, United States of America.

Objective: To determine the effect of intramuscular progesterone on the vaginal immune response of pregnant women with a history of prior preterm birth.

Methods: A prospective, cohort study of women at 11-16 weeks gestation, ≥18 years of age, and carrying a singleton pregnancy was conducted from June 2016 to August 2017 after IRB approval. Women in the progesterone arm had a history of preterm birth and received weekly intramuscular 17-hydroxyprogesterone caproate. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0209346PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312274PMC
December 2018
4 Reads

Vaginosis. Vaginal microbiota.

Enferm Infecc Microbiol Clin 2018 Dec 26. Epub 2018 Dec 26.

Departamento de Biología Funcional, Universidad de Oviedo, Oviedo, España; Fundación de Investigación Oftalmológica, Instituto Oftalmológico Fernández-Vega, Oviedo, España; Fundación para la Investigación y la Innovación Biosanitaria del Principado de Asturias (FINBA), Oviedo, España.

The latest advances in the vaginal microbiome and molecular diagnosis of bacterial vaginosis have allowed for a better knowledge of this entity, characterising aspects of its pathogenesis and the establishment of the vaginal biolayer, the models and new theories of its aetiology, how it is transmitted, with it being considered nowadays as a probable sexually transmitted infection, the separation of other entities such as aerobic vaginosis, its molecular diagnosis and treatment with new molecules to prevent frequent relapses. This entity and the study of the vaginal microbiome have made it possible to consider these infections as a polymicrobial syndrome, putting an end to the dogma: one microorganism, one disease. In addition, a lesser-known entity such as aerobic vaginosis and the methods for its detection are updated. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0213005X183038
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http://dx.doi.org/10.1016/j.eimc.2018.11.009DOI Listing
December 2018
5 Reads

Trichomonas vaginalis infection and the diagnostic significance of detection tests among Ghanaian outpatients.

BMC Womens Health 2018 12 27;18(1):206. Epub 2018 Dec 27.

Department of Medical Laboratory Sciences, School of Biomedical and Allied Health Sciences, University of Ghana, Korle-bu, Accra, Ghana.

Background: There is little data on Trichomonas vaginalis infection in Ghana. This study evaluated the prevalence of trichomoniasis using different diagnostic methods and determined the risk factors for infection in patients.

Methods: A structured questionnaire was administered. Read More

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http://dx.doi.org/10.1186/s12905-018-0699-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307156PMC
December 2018
6 Reads
1.657 Impact Factor

Genital ulcers caused by herpes simplex virus.

Enferm Infecc Microbiol Clin 2019 04 21;37(4):260-264. Epub 2018 Dec 21.

Molecular Diagnostics Deparment, Vircell Microbiologists, Parque Tecnológico de la Salud, Granada, España. Electronic address:

Genital herpes is a sexually transmitted disease caused by herpes simplex virus type1 (HSV-1) and type2 (HSV-2) belonging to the alphaherpesvirus family, that includes the varicella zoster virus. HSV infection continues to be the most common cause of vulvar ulcers among the sexually active population. Its incidence increases every year. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0213005X183037
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http://dx.doi.org/10.1016/j.eimc.2018.10.020DOI Listing
April 2019
13 Reads

Gardnerella vaginalis in perinatology: An overview of the clinicopathological correlation.

Malays J Pathol 2018 Dec;40(3):267-286

Universiti Kebangsaan Malaysia Medical Centre, Departments of Pathology, Kuala Lumpur, Malaysia.

Gardnerella vaginalis (GV) is a facultatively anaerobic gram-variable bacillus and is the major organism involved in bacterial vaginosis. GV-associated bacterial vaginosis has been associated with adverse pregnancy outcomes include preterm parturition and subclinical chorioamnionitis. Inflammatory response induced by GV presents paediatric problems as well. Read More

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December 2018
16 Reads

Bacterial Vaginosis and Desquamative Inflammatory Vaginitis.

N Engl J Med 2018 12;379(23):2246-2254

From the Department of Obstetrics and Gynecology, Helsinki University Hospital, Helsinki (J.P.); and the Department of Medicine, University of British Columbia, Vancouver, Canada (R.C.B.).

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http://www.nejm.org/doi/10.1056/NEJMra1808418
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http://dx.doi.org/10.1056/NEJMra1808418DOI Listing
December 2018
10 Reads

Correlation between antifungal resistance and virulence factors in Candida albicans recovered from vaginal specimens.

Microb Pathog 2019 Mar 15;128:13-19. Epub 2018 Dec 15.

Department of Microbiology and Immunology, Faculty of Pharmacy, Ain Shams University, African Union Organization St. Abbassia, Cairo 11566, Egypt; Department of Microbiology and Immunology, School of Pharmacy & Pharmaceutical Industries, Badr University in Cairo (BUC), Entertainment Area, Badr City, Cairo, Egypt. Electronic address:

Candida albicans is considered as the leading species causing vulvovaginal candidiasis. Numerous virulence determinants and escalating resistance to antifungal therapy have contributed to its pathogenicity. However, correlation between resistance profiles and virulence patterns of C. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08824010183180
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http://dx.doi.org/10.1016/j.micpath.2018.12.028DOI Listing
March 2019
12 Reads

Protective Effects of cis-2-Dodecenoic Acid in an Experimental Mouse Model of Vaginal Candidiasis.

Biomed Environ Sci 2018 Nov;31(11):816-828

Key Laboratory for Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials (IAM), Nanjing University of Posts and Telecommunications, Nanjing 210023, Jiangsu, China.

Objective: To evaluate the efficacy of cis-2-dodecenoic acid (BDSF) in the treatment and prevention of vaginal candidiasis in vivo.

Methods: The activities of different concentrations of BDSF against the virulence factors of Candida albicans (C. albicans) were determined in vitro. Read More

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http://www.besjournal.com/Articles/Archive/2018/No11/201812/
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http://dx.doi.org/10.3967/bes2018.109DOI Listing
November 2018
14 Reads

Chitosan-hydroxypropyl methylcellulose tioconazole films: A promising alternative dosage form for the treatment of vaginal candidiasis.

Int J Pharm 2019 Feb 12;556:181-191. Epub 2018 Dec 12.

Instituto de Química Rosario (IQUIR, CONICET-UNR), Suipacha 531, Rosario S2002LRK, Argentina; Área Técnica Farmacéutica, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, Rosario S2002LRK, Argentina. Electronic address:

Vaginal candidiasis is considered a frequent opportunistic mucosal infection and the second most common cause of vaginitis after bacterial vaginosis. In this work, different vaginal films based on chitosan, hydroxypropyl methylcellulose and blends of these polymers containing tioconazole, were developed and thoroughly characterized to improve the conventional therapeutics of vaginal candidiasis. Mechanical properties, swelling, adhesiveness, morphology, antifungal activity, hemocompatibility and cytotoxicity were evaluated. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03785173183091
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http://dx.doi.org/10.1016/j.ijpharm.2018.12.011DOI Listing
February 2019
18 Reads

A performance evaluation of an immuno-latex chromatography card for the rapid detection of Candida spp.

J Microbiol Methods 2019 Feb 10;157:4-8. Epub 2018 Dec 10.

Department of Clinical Laboratory, the First Hospital of Quanzhou Affiliated to Fujian Medical University, Quanzhou, China.

This report evaluates the performance and species specificity of an immuno-latex chromatography card (ICC) for rapid detection of Candida spp. Double-manipulator single-blind Gram staining smear examination (GSSE) and ICC were used to analyze 354 vaginal discharge specimens (VDS) (including 98 tested as positive by GSSE) from women with suspected candidal vaginitis, simulated specimens with a concentration gradient, and vaginitis causing organism suspensions (0.9% NaCl) of 22 species from nine genera. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01677012183045
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http://dx.doi.org/10.1016/j.mimet.2018.12.005DOI Listing
February 2019
13 Reads

Influence of Nursing Intervention on Recurrent Vulvovaginal Candidiasis Patients Treated with ATP-infrared Bio-effect Technique.

Authors:
Wenxiang Li

Iran J Public Health 2018 Oct;47(10):1511-1519

Dept. of Gynecology, Women & Children's Health Care Hospital of Linyi, Linyi, China.

Background: We aimed to investigate the influence of nursing intervention on recurrent vulvovaginal candidiasis (RVVC) patients treated with adenosine triphosphate (ATP)-infrared bio-effect technique.

Methods: Sixty eight RVVC patients of Women & Children's Health Care Hospital of Linyi were randomly divided into intervention group (n=34) and control group (n=34) from to June, 2016 to June 2017. Patients in intervention group received the one-to-one intervention based on ATP-infrared bio-effect technique; the individualized nursing intervention program was developed. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277732PMC
October 2018
2 Reads

Spectrum of parasitic infections in centrifuged urine sediments from a newly developed tertiary care centre in Central India.

J Parasit Dis 2018 Dec 29;42(4):608-615. Epub 2018 Oct 29.

3Department of Microbiology, All India Institute of Medical Sciences, Saket Nagar, Bhopal, MP 462024 India.

Detection of urinary parasites is relatively rare and incidental finding in routine urine examination. Common urinary parasitic infections as described in literature include Trichomonas, and Microfilaria. is known to cause vaginitis and urethritis, and may be found in urine sediments. Read More

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http://dx.doi.org/10.1007/s12639-018-1043-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261132PMC
December 2018
17 Reads

Genital Tract Pathology in Female Pet Guinea Pigs (Cavia porcellus): a Retrospective Study of 655 Post-mortem and 64 Biopsy Cases.

J Comp Pathol 2018 Nov 19;165:13-22. Epub 2018 Oct 19.

Institute of Veterinary Pathology, Freie Universität Berlin, Robert-von-Ostertagstrase 15, Germany. Electronic address:

Disorders of the female genital tract are among the most common disorders in pet guinea pigs (Cavia porcellus); however, knowledge of many aspects of these disorders is sparse, especially regarding their incidence and age distribution. Ovarian cysts, as the most common genital tract disorder in guinea pigs, have been investigated in detail; however, information on the nature of these cysts is inconsistent. The present study reviewed genital tract disorders occurring within 655 full post-mortem examinations of intact female pet guinea pigs and 64 female genital tract biopsies examined over a 22. Read More

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http://dx.doi.org/10.1016/j.jcpa.2018.09.001DOI Listing
November 2018
2 Reads

Intravaginal Device-Type and Treatment-Length for Ovine Estrus Synchronization Modify Vaginal Mucus and Microbiota and Affect Fertility.

Animals (Basel) 2018 Nov 29;8(12). Epub 2018 Nov 29.

Dpto. de Reproduccion Animal, INIA, Avda. Puerta de Hierro s/n., 28040 Madrid, Spain.

Induction and synchronization of estrus and ovulation in sheep is based on intravaginal progestagen-impregnated polyurethane sponges or progesterone-loaded silicon-based devices (CIDR), in either short- (6⁻7 days) or long-term (12⁻14 days) protocols. Bearing in mind that the use of intravaginal sponges in long-term protocols has been related to the presence of vaginitis at removal, we compared the effects of sponges and CIDRs, maintained during either 7 or 14 days, on vaginal features (characteristics of vaginal mucus discharge, pH and microbiota) and fertility under field conditions. Almost all the ewes treated with intravaginal sponges showed vaginal discharge at device withdrawal, which was purulent and/or bloody in around 15% and 80% of the females treated for 7 and 14 days, respectively. Read More

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http://dx.doi.org/10.3390/ani8120226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316288PMC
November 2018
2 Reads

Intralesional and subcutaneous application of Viscum album L. (European mistletoe) extract in cervical carcinoma in situ: A CARE compliant case report.

Medicine (Baltimore) 2018 Nov;97(48):e13420

Institute for Applied Epistemology and Medical Methodology at the University of Witten/Herdecke.

Rationale: Carcinoma in situ (CIS) of the uterine cervix is a premalignant condition of squamous epithelium. The standard treatments are excision and ablation procedures; for women with positive margins, hysterectomy is recommended.

Patient Concerns: A 47-year-old Peruvian woman with recurrent candidal vaginitis had been diagnosed with colpocervicitis and squamous metaplasia 8 years ago, which were not treated. Read More

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http://dx.doi.org/10.1097/MD.0000000000013420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283068PMC
November 2018
2 Reads

Bacterial vaginosis: An insight into the prevalence, alternative treatments regimen and it's associated resistance patterns.

Microb Pathog 2019 Feb 28;127:21-30. Epub 2018 Nov 28.

Atta-Ur-Rahman School of Applied Bio-Sciences, Department of Healthcare Biotechnology, National University of Sciences and Technology, Islamabad, 44000, Pakistan. Electronic address:

Bacterial Vaginosis (BV) is a complex polymicrobial infection of vagina that shifts the paradigms of vaginal flora from lactobacilli to opportunistic pathogens. BV is catagorized by greyish white discharge, pH greater than 4.5. Read More

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http://dx.doi.org/10.1016/j.micpath.2018.11.046DOI Listing
February 2019
26 Reads
2.000 Impact Factor

Anti-Inflammatory Effect of Surfactant Lipid in the Vaginal Mucosa: A Pilot Study.

J Low Genit Tract Dis 2019 Jan;23(1):71-74

Department of Obstetrics & Gynecology, Pennsylvania State University College of Medicine, Hershey, PA.

Objective: The aim of the study was to test the hypothesis that vaginal administration of surfactant lipids, which may counter-balance the proinflammatory effects of vaginal surfactant protein A, will decrease proinflammatory cytokines and increase anti-inflammatory cytokines in vaginal mucosal fluid in healthy women.

Materials And Methods: Three groups of healthy cycling women were randomized to receive vaginally a single dose of the following: (1) low-dose calfactant, a type of surfactant lipids, 0.8 mg/ml; (2) high-dose calfactant 8. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000448DOI Listing
January 2019
3 Reads

Device-based treatment for vaginal wellness.

Semin Cutan Med Surg 2018 Dec;37(4):226-232

Yale University School of Medicine, New Haven, Connecticut, USA.

Genitourinary syndrome of menopause (GSM), encompassing the disorders of atrophic vaginitis, urinary incontinence, and pelvic prolapse, affects the majority of postmenopausal women, as well as patients who are undergoing breast cancer treatement, post-ovarectomy, post-radiation, and breast-feeding. There is a need for better treatment options for these common conditions that adversely affect physical function and quality of life and that are often underserved by existing options. Lasers have been used to treat genitourinary tissue for over 40 years, and over the past decade, several lasers and radiofrequency devices have been developed and clinically tested for the treatment of GSM, with an accumulating body of evidence demonstrating their safety and efficacy. Read More

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https://scmsjournal.com/article/buy_now/?id=797
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http://dx.doi.org/10.12788/j.sder.2018.052DOI Listing
December 2018
20 Reads

Aerobic vaginitis in late pregnancy and outcomes of pregnancy.

Eur J Clin Microbiol Infect Dis 2019 Feb 22;38(2):233-239. Epub 2018 Nov 22.

Department of Gynecology and Obstetrics, Tianjin Medical University General Hospital, No.154 Anshan Road, Heping District, Tianjin, 300052, China.

The purpose of this study was to investigate the risk factors and pregnancy outcomes for aerobic vaginitis (AV) in late pregnancy. A total of 624 pregnant women who were treated in the perinatal unit at Tianjin Medical University General Hospital and 365 nonpregnant women who were evaluated at a health management center from January 2015 to June 2016 were recruited for this case-control study. A questionnaire covering personal hygiene habits and sociodemographic factors was administered to pregnant women to analyze risk factors for AV. Read More

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http://dx.doi.org/10.1007/s10096-018-3416-2DOI Listing
February 2019
15 Reads

Culture- and PCR-based detection of BV associated microbiological profile of the removed IUDs and correlation with the time period of IUD in place and the presence of the symptoms of genital tract infection.

Ann Clin Microbiol Antimicrob 2018 Nov 22;17(1):40. Epub 2018 Nov 22.

Institute of Clinical Microbiology, Albert Szent-Györgyi Clinical Center, Faculty of Medicine, University of Szeged, Semmelweis St. 6, Szeged, 6725, Hungary.

Objectives: The long-term use of intrauterine devices (IUDs) may lead to biofilm formation on the surface. The aim of this study was to perform the culture- and PCR-based detection of bacteria/fungi from the biofilm of the removed IUDs with different time periods in place.

Methods: For a 2-year period, 100 IUD users were involved in the study. Read More

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http://dx.doi.org/10.1186/s12941-018-0293-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249738PMC
November 2018
16 Reads

Calophyllum inophyllum in vaginitis treatment: Stimulated by electroporation with an in vitro approach.

Adv Clin Exp Med 2019 Feb;28(2):223-228

Department of Molecular and Cellular Biology, Faculty of Pharmacy with Division of Laboratory Diagnostics, Wroclaw Medical University, Poland.

Background: Vaginitis is one of the most common problems in clinical medicine and is cited most often during visits to obstetricians and gynecologists. Most of the inflammation cases are caused by candidiasis trichomoniasis and bacterial vaginosis. Therefore, treatment of vaginal infections must use antibiotic or antifungal drugs, which often provide quick relief to the patient. Read More

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http://dx.doi.org/10.17219/acem/87045DOI Listing
February 2019
16 Reads

Application of conjugated estrogen cream in the treatment of postmenopausal atrophic vaginitis.

Pak J Pharm Sci 2018 Sep;31(5(Special)):2283-2286

Obstetrics and Gynecology Department, Beijing Shijitan Hospital Affiliated to Capital Medical University, Beijing, China.

To observe and analyze the effect of conjugated estrogen cream in the treatment of postmenopausal atrophic vaginitis. The 160 patients clearly diagnosed with postmenopausal atrophic vaginitis and treated in our hospital were selected as subjects and divided into study group and reference group with equal number of cases. The reference group was treated with compound metronidazole suppository, while the study group was treated with conjugated estrogen cream. Read More

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September 2018
21 Reads

[Interaction between vaginal micro-environment alterations and HPV16 infection in cervical intraepithelial neoplasia].

Zhonghua Liu Xing Bing Xue Za Zhi 2018 Nov;39(11):1486-1490

Department of Epidemiology, School of Public Health, Shanxi Medical University, Taiyuan 030001, China.

To explore the effect of vaginal micro-environment alterations and HPV16 infection and their interaction in the progression of cervical intraepithelial neoplasia. The participants of this study came from the cervical lesions study cohort in Shanxi province, including 623 women with normal cervical (NC), 303 patients with pathogenically diagnosed low-grade cervical intraepithelial neoplasia (CINⅠ) and 93 patients with pathogenically diagnosed high-grade cervical intraepithelial neoplasia (CINⅡ/Ⅲ). The data of the demographic characteristics of the study subjects and factors related to cervical intraepithelial neoplasia were collected, and HPV16 infection were detected by using flow-through hybridization technology and H(2)O(2), β-glucuronidase, clotting enzyme, neuraminidase and leucocyte esterase in vaginal secretions were detected by using the combined detection kit of aerobic vaginitis and bacterial vaginosis. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0254-6450.2018.11.013DOI Listing
November 2018
11 Reads