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Eur J Obstet Gynecol Reprod Biol 2021 May 5;262:36-39. Epub 2021 May 5.

Ministry of Health Ankara City Hospital, Department of Obstetrics and Gynecology, Turkey.

Objective: The perineal body is critical for maintaining the integrity of the pelvic floor, especially in females as it can be injured during vaginal delivery. This study aimed to evaluate the effect of childbirth on perineal body dimensions by using a transperineal 2D ultrasound.

Study Design: This prospective cohort study was performed in a tertiary obstetric care center. Read More

J Pediatr Adolesc Gynecol 2021 May 11. Epub 2021 May 11.

Gynaecology Department, Manchester University NHS Foundation Trust, Saint Mary's Hospital, Oxford Road, Manchester, M13 9WL, United Kingdom.

Background: 46XY pure gonadal dysgenesis (Swyer syndrome) is a rare disorder of sexual development. Patients have a 46XY karyotype, though phenotypically appear female with normal external genitalia and vagina. While patients exhibit normal Mullerian structures (uterus, fallopian tubes and vagina); they possess a pair of bilateral undifferentiated gonad streaks. Read More

Curr Med Res Opin 2021 May 14. Epub 2021 May 14.

Department of Pharmacotherapy, -Epidemiology and Economy, Faculty Pharmacy, University of Groningen, Groningen, Netherlands.

Background: A very common side effect of non-vitamin K antagonist oral anticoagulant (NOAC) is (minor) bleeding. Data about impact and costs of minor bleeds in NOAC therapy is still limited or not present in current literature. In this patient orientated study, we aim to provide an estimate of the costs of minor bleeds in patients with atrial fibrillation (AF) treated with a NOAC. Read More

Int Urogynecol J 2021 May 14. Epub 2021 May 14.

Department of Obstetrics and Gynecology, Albany Medical Center, Albany, NY, USA.

Introduction And Hypothesis: This was a planned secondary analysis of a systematic review that described sexual function outcomes following pelvic organ prolapse (POP) surgery. We aimed to describe the relationship of pre- and postoperative vaginal anatomic measures with sexual function outcomes. Data Sources included the Medline, Embase, and clinicaltrials. Read More

Int Urogynecol J 2021 May 14. Epub 2021 May 14.

Croydon University Hospitals NHS Trust, 530 London Road, Croydon, CR7 7YE, UK.

Rising rates of obstetric anal sphincter injury (OASI) led to a collaborative effort by the Royal College of Obstetricians and Gynaecologists (RCOG) and the Royal College of Midwives (RCM) to develop and evaluate the OASI Care Bundle (OASI-CB). The OASI-CB comprises four practices (antenatal discussion about OASI, manual perineal protection, mediolateral episiotomy at 60° from the midline, and systematic examination of the perineum, vagina and ano-rectum after vaginal birth) and was initially implemented as part of a quality improvement (QI) project-"OASI1"-in 16 maternity units across Great Britain. Evaluation of the OASI1 project found that the care bundle reduced OASI rates and identified several barriers and enablers to implementation. Read More

Cryo Letters 2020 Mar-Apr;41(2):106-114

Department of Zoology, Islamia College University, Peshawar, Khyber Pakhtunkhwa (KPK), Pakistan.

Background: Fructose is considered a vital energy source for metabolic events occurring naturally in the seminal plasma of buffalo spermatozoa.

Objective: To explore the effect of different concentrations of fructose and glycerol in tris citric acid extender on post thaw quality and in vivo fertility of buffalo spermatozoa.

Materials And Methods: Semen was collected from three bulls through artificial vagina (42 °C). Read More

Cryo Letters 2020 May-Jun;41(3):145-153

Animal Reproduction Laboratory, Animal Sciences Institute, National Agricultural Research Center, Islamabad, Pakistan.

Background: Alpha-tocopheryl succinate, a major chain-splitting antioxidant, is the most effective form of vitamin E and may be used in the semen extender for cryopreservation of buffalo spermatozoa.

Objective: To use different concentrations of alpha-tocopheryl succinate (T1, 0.3 mM, T2, 0. Read More

J Anim Sci Technol 2021 Jan 31;63(1):58-68. Epub 2021 Jan 31.

Central Department of Biotechnology, Tribhuvan University, Kirtipur, Kathmandu 44618, Nepal.

Several herbs including are known to possess conceptive property. In the present study, mouse spermatozoa were incubated with ethanol extract of leaves. The effect of extract on acrosome exocytosis was studied by labeling spermatozoa with fluorescein isothiocyanate (FITC) peanut agglutinin and by staining with Coomassie blue. Read More

J Anim Sci Technol 2021 Jan 31;63(1):46-57. Epub 2021 Jan 31.

Animal Science Department, Ahmadu Bello University, Zaria, Kaduna State 810241, Nigeria.

Fruits with antioxidant enrichment can be an economically affordable supplement for mitigating oxidative damage prone spermatozoa membrane pathologies. Computer-assisted sperm analyzer and oxidative status were utilized to evaluate the impact of watermelon () fortification of dextrose saline as diluent for rooster semen and fertility response of hens inseminated. Watermelon juice and dextrose saline were used to formulate diluent of 7 treatments consisting of unextended semen (positive control), 10%, 20%, 30%, 40%, 50% and only dextrose saline (negative control) designated as Treatments 1-7. Read More

Ann Transl Med 2021 Apr;9(7):604

Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Background: Vaginal laxity may result from trauma to the pelvic floor muscle, which may affect patients' sensation and quality of life. Vaginal rejuvenation, including surgical or nonsurgical interventions, aims to improve laxity. In this study, we aimed to establish a strategy for vaginal rejuvenation by comparing surgical and nonsurgical methods. Read More

Exp Ther Med 2021 Jul 23;22(1):674. Epub 2021 Apr 23.

First Obstetrics and Gynecology Clinic, 'George Emil Palade' University of Medicine, Pharmacy, Science and Technology, 540136 Târgu Mures, Romania.

The aim of this study was to present our experience of 18 cases of abdominal radical trachelectomy (ART), including 5 performed during pregnancy, analyzing patient selection, surgical complications, and oncological and obstetrical outcomes. This reproductive study included all early stage cervical cancer patients referred for ART at the 1st Obstetrics and Gynecology Clinic of the Emergency Clinical County Hospital Targu Mures, between 2010 and 2020. A total of 19 women were considered for ART, and only 1 case required conversion to radical hysterectomy. Read More

Clin Cosmet Investig Dermatol 2021 6;14:425-436. Epub 2021 May 6.

Union Square Medical Associates, San Francisco, CA, USA.

Although the erythema migrans (EM) skin rash is traditionally considered a hallmark of Lyme disease, other dermatological manifestations of the tickborne disease are less well known. We describe a 49-year-old woman with erosive genital ulcerations, secondary EM rashes and jagged skin lesions associated with Lyme disease. The skin rashes exhibited fibers characteristic of Morgellons disease. Read More

BMJ Case Rep 2021 May 13;14(5). Epub 2021 May 13.

Pathology, Queen Elizabeth Hospital, London, London, UK.

A 52-year-old long-term user of the levonorgestrel-releasing intrauterine system (LNG-IUS) presented with vaginal bleeding. Endometrial biopsy was performed and revealed endometrioid adenocarcinoma. The patient had a laparoscopic hysterectomy and bilateral salpingo-oophorectomy. Read More

J Dairy Res 2021 May 14:1-8. Epub 2021 May 14.

Facultad de Ciencias Agrarias y Alimentarias, Instituto de Producción Animal, Universidad Austral de Chile, Valdivia, Chile.

The aim of the study was to assess the effect of the summer thermal environment on physiological responses, behaviour, milk production and its composition on grazing dairy cows in a temperate climate region, according to the stage of lactation. Twenty-nine Holstein Friesian multiparous cows were randomly selected and divided into two groups, according to the days in milk, as mid-lactation (99 to 170 d in milk, n = 15) and late lactation (225 to 311 d in milk, n = 14). The comprehensive climate index (CCI) was used to classify the hour of each day as thermoneutral or heat stress, considering a threshold value of CCI of 20°C. Read More

BMC Microbiol 2021 May 13;21(1):145. Epub 2021 May 13.

Division of Diagnostic and Applied Microbiology, Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Canada.

Background: Group B streptococci (GBS) are important neonatal bacterial pathogens that can cause severe invasive disease in the newborn. It is thought that in many cases of invasive neonatal GBS disease, the bacteria ascend the vagina into the uterus and infect the amniotic fluid surrounding the fetus. Important constituents of this environment include the polyols or sugar alcohols of which erythritol, sorbitol and mannitol are examples. Read More

J Investig Med High Impact Case Rep 2021 Jan-Dec;9:23247096211014690

Howard University Hospital, Washington, DC, USA.

Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome is a sexual developmental disorder. In this disorder, there is a congenital absence of the uterus and vagina with normal external genitalia. The etiology is not well understood. Read More

J Obstet Gynaecol Can 2021 May 10. Epub 2021 May 10.

Mount Sinai Hospital, 700 University Avenue, 8-816 Toronto, Ontario, M5G 1Z5. Electronic address:

Objective: The incidence of post-hysterectomy vault prolapse following native tissue repair has been reported to be as high as 43%. The optimal way to maintain vault support is unknown. Our aim was to evaluate the long-term efficacy of modified McCall culdoplasty during vaginal hysterectomy for symptomatic uterine prolapse in preventing the recurrence of vaginal vault prolapse. Read More

Am J Obstet Gynecol 2021 May 10. Epub 2021 May 10.

Department of Obstetrics, Gynecology & Reproductive Science, University of California San.

Background: There is limited literature identifying racial and ethnic health disparities among surgical modalities and outcomes in the field of urogynecology and specifically pelvic organ prolapse surgery.

Objective: To evaluate differences in surgical approach for apical vaginal prolapse and postoperative complications by race and ethnicity STUDY DESIGN: This is a retrospective cohort study of women undergoing surgical repair for apical vaginal prolapse between 2014 and 2017 using data from the American College of Surgeons National Surgical Quality Improvement Program. Patients were eligible for inclusion if they underwent either a vaginal colpopexy or abdominal sacrocolpopexy (ASC). Read More

Arch Gynecol Obstet 2021 May 13. Epub 2021 May 13.

Obstetrics and Gynecology Department, Kasr AlAini Hospital Cairo University, 11 Eid Mostafa from King Faisal Street Haram Giza, Cairo, 12111, Egypt.

Objective: To assess the safety and efficacy of hyoscine butyl bromide (HBB) in primipara with prolonged 1st stage of labor.

Materials And Methods: A double-blinded randomized controlled trial included 100 primiparas diagnosed with prolonged labor. They were randomly divided two equal groups. Read More

J Int Med Res 2021 May;49(5):3000605211014797

Department of Paediatrics, Tri-Service General Hospital, National Defense Medical Centre, Taipei.

The coexistence of imperforate hymen and vaginal septum is rare and their ability to mimic malignant manifestations have not been frequently reported. This current case report describes a 13-year-old girl that presented with cyclic abdominal pain for 6 months. She was found to have a huge mass via abdominal plain film X-ray and sonography, with inexplicably high levels of serum carcinoembryonic antigen, cancer antigen (CA)-19-9 and CA-125. Read More

J Int Med Res 2021 May;49(5):3000605211013226

Medical Department, ITF Research Pharma S.L.U., Madrid, Spain.

Objective: To assess the efficacy, acceptability, and tolerability of a vaginal cream based on plant extracts for treating signs and symptoms of vulvovaginitis (VV) (Zelesse cream®), either as monotherapy (non-infectious VV) or adjuvant to antimicrobial therapy (infectious VV).

Methods: This prospective, observational, multicenter study included women who attended outpatient offices for VV. The severity of signs (vaginal discharge, erythema, and edema) and symptoms (pruritus, burning, and dysuria) was assessed before and after 15±5 days of daily treatment with Zelesse cream on a 4-point scale (18-point global score). Read More

Am Fam Physician 2021 May;103(10):597-604

AdventHealth Orlando Family Medicine Residency Program, Orlando, FL, USA.

Dyspareunia is recurrent or persistent pain with sexual intercourse that causes distress. It affects approximately 10% to 20% of U.S. Read More

Am Fam Physician 2021 May;103(10):628-629

Binghamton University School of Pharmacy and Pharmaceutical Sciences, Binghamton, NY, USA.

Zhongguo Zhong Yao Za Zhi 2021 Apr;46(8):1935-1942

School of Chinese Materia Medica, Beijing University of Chinese Medicine Beijing 100029, China.

Myrtus communis is a traditional medicinal aromatic plant in the Mediterranean. At present, the plant has been introduced and cultivated in the southern part of China, and it is mostly used for ornamental or cosmetic purposes. Based on literature analysis and the theory of Chinese medicine, we discussed the medicinal parts and properties of M. Read More

Case Rep Womens Health 2021 Apr 17;30:e00313. Epub 2021 Apr 17.

Urogynecology Center, Kameda Medical Center, Kamogawa, Chiba, Japan.

Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a rare congenital anomaly that results in Müllerian agenesis that affects the uterus and upper two-thirds of the vagina. Sigmoid vaginoplasty is a surgical treatment option; however, vaginal prolapse may result as a complication of the sigmoid neovagina. There are no standards for treatment due to the rarity of this condition. Read More

JSLS 2021 Apr-Jun;25(2)

Department of Gynecological Endoscopy, Eva Women's Hospital, Ahmedabad, India.

Background And Objectives: The aim of this study was to define new techniques for performing vaginal closure with endo-staplers to prevent tumor spillage during laparoscopic surgeries for endometrial cancer and early stage cervical cancer.

Methods: Thirteen patients were retrospectively studied for the use of endo-staplers for vaginal closure before colpotomy during laparoscopic surgeries for endometrial cancer and early stage cervical cancer to prevent tumor spillage.

Results: There were no short-term or any long-term complication related to the use of the endo-staplers for colpotomy in the surgeries included in this study. Read More

mSphere 2021 May 12;6(3). Epub 2021 May 12.

Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, USA.

is a frequent member of the urogenital microbiota. Given the association between and bacterial vaginosis (BV), significant efforts have been focused on characterizing this species in the vaginal microbiota. However, also is a frequent member of the urinary microbiota. Read More

J Matern Fetal Neonatal Med 2021 May 12:1-6. Epub 2021 May 12.

Faculty of Medicine, Department of Obstetrics and Gynecology, Rambam Health Care Campus, Technion - Israel Institute of Technology, Haifa, Israel.

Objective: In 2014, the American College of Obstetricians and Gynecologists (ACOG) and the Society for Maternal Fetal Medicine (SMFM) published an Obstetric Care Consensus for safe prevention of primary cesarean delivery. We aimed to assess whether these guidelines decreased the primary CD rate during the second stage of labor, in our department.

Design, Setting, And Population: A retrospective cohort study of all women reaching the second stage of labor, at term, in a single university-affiliated medical center between2010 and 2017. Read More

Rev Bras Ginecol Obstet 2021 Apr 12;43(4):323-328. Epub 2021 May 12.

Department of Obstetrics, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

Complete hydatidiform mole (CHM) is a rare type of pregnancy, in which 15 to 20% of the cases may develop into gestational trophoblastic neoplasia (GTN). The diagnostic of GTN must be done as early as possible through weekly surveillance of serum hCG after uterine evacuation. We report the case of 23-year-old primigravida, with CHM but without surveillance of hCG after uterine evacuation. Read More

J Laparoendosc Adv Surg Tech A 2021 May 12. Epub 2021 May 12.

Department of Pediatric Surgery, Cairo University, Cairo, Egypt.

This study aims at evaluating the feasibility and outcome of a laparoscopically assisted rectal and vaginal pull-through procedure in the same setting for cases of long common channel in a cloaca >3 cm in length. I have 4 cases with a cloaca with long common channel >3 cm in length diagnosed by cloacogram and cystoscopy. As for the ages of our cases, two of them were 1 year old, and the other 2 cases were 2 years old. Read More