Qualitative differences in cellular immunogenicity elicited by hepatitis C virus T-Cell vaccines employing prime-boost regimens.
- Wendy G Tan,
- Iryna Zubkova,
- Alla Kachko,
- Frances Wells,
- Heiko Adler,
- Gerd Sutter,
- Marian E Major
oncolytic vaccinia virus, is enhanced by radiation and chemotherapy. The purpose of this study
was to determine the safety of GL-ONC1 when delivered intravenously with chemoradiotherapy
to patients with primary, non-metastatic head and neck cancer.
EXPERIMENTAL DESIGN: Patients with locoregionally advanced unresected, non-metastatic
carcinoma of the head/neck, excluding stage III-IVA p16-positive oropharyngeal cancers, were
treated with escalating doses and cycles of intravenous GL-ONC1, along with radiotherapy and
chemotherapy. Read More