1,229 results match your criteria Uveitis Intermediate


Noninfectious Intermediate, Posterior, or Panuveitis: Results from the Retrospective, Observational, International EyeCOPE Study.

Ophthalmol Ther 2021 Jun 12. Epub 2021 Jun 12.

Department of Ophthalmology, Faculty of Medicine, Gazi University, 13th Floor, Besevler, Cankaya, 06500, Ankara, Turkey.

Introduction: The EyeCOPE study characterized noninfectious intermediate posterior, or panuveitis (NIIPPU) before biologic agents were widely available.

Methods: This retrospective, observational study included adults with NIIPPU attending a routine ophthalmological visit. Data were collected from the study visit and medical records. Read More

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The clinical presentation and treatment outcomes of ocular tuberculosis: a 5-year experience in an endemic area.

Int Ophthalmol 2021 May 26. Epub 2021 May 26.

Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital and Alice Ho Miu Ling Nethersole, The Chinese University of Hong Kong, Hong Kong SAR, China.

Purpose: To report the clinical presentations of ocular tuberculosis infection (OTB) and the treatment regimen and outcome in an endemic area.

Methods: This is a retrospective case series of patients with presumed OTB treated in a tertiary teaching hospital in Hong Kong in 2014-2019.

Results: Among the nineteen patients recruited, the most common clinical presentation of OTB was retinal vasculitis (42. Read More

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En face optical coherence tomography patterns in patients with angiographically documented uveitic macular edema: a cross-sectional retrospective study.

Int Ophthalmol 2021 May 20. Epub 2021 May 20.

Department of Ophthalmology, Dokuz Eylul University, İzmir, Turkey.

Purpose: To elucidate the en face optical coherence tomography (OCT) patterns of macular edema in eyes with angiographically documented uveitic macular edema (UME) and compare visual acuity (VA), OCT and OCT-angiography (OCT-A) parameters among the morphological subgroups.

Methods: Thirty-nine eyes of 29 patients with angiographically proven UME were enrolled into the study. All patients underwent comprehensive ophthalmological examination including structural OCT and OCT-A in addition to fluorescein angiography. Read More

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Differential Diagnosis of Vitritis in Adult Patients.

Ocul Immunol Inflamm 2021 May 18:1-10. Epub 2021 May 18.

Department of Ophthalmology, Reference Center in Rare Diseases, DHU Sight Restore, Hôpital Pitié Salpêtrière, Sorbonne Université, Paris, France.

The term "vitritis" refers to the presence of a cellular infiltration of the vitreous body, usually in the context of an intraocular inflammation, but not exclusively. Intermediate uveitis is the most prominent cause of vitritis, including infectious and auto-immune/auto-inflammatory etiologies. Corticosteroids and immunosuppressive therapies should not be started before ruling out the infectious causes of vitritis, especially in immunosuppressed individuals. Read More

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Persistent Remnants of Dexamethasone Intravitreal Implant Over 24 Months in a Patient Suffering from Anterior and Intermediate Uveitis Associated with Macular Edema.

Klin Monbl Augenheilkd 2021 04 30;238(4):454-457. Epub 2021 Apr 30.

Retina Department, Ophthalmology Center, RétinElysée, Lausanne, Switzerland, Lausanne, Switzerland.

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Automated Quantification of Vitreous Hyperreflective Foci and Vitreous Haze Using Optical Coherence Tomography in Uveitis Patients.

Retina 2021 Apr 12. Epub 2021 Apr 12.

Department of Ophthalmology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of Korea.

Purpose: Development of an automated method to quantify the count of vitreous hyperreflective foci (vHF) and intensity of vitreous haze in uveitis patients by optical coherence tomography (OCT).

Methods: A method based on deep learning to automatically segment the vHF, vitreous and retinal pigment epithelium (RPE) in OCT was developed using 1,058 scans from 88 OCT volumes of 33 patients with intermediate, posterior or panuveitis. Based on segmented images, the vHF count and the relative intensity of vitreous to RPE (VIT/RPE-relative intensity) was quantified. Read More

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Epidemiology of Childhood Uveitis in a Tertiary Care Center: A 20-Year Study.

Klin Monbl Augenheilkd 2021 Apr 14;238(4):469-473. Epub 2021 Apr 14.

Jules-Gonin Eye Hospital, Department of Ophthalmology, University of Lausanne, Lausanne, Switzerland.

Purpose: To investigate demographics and causes of pediatric uveitis in a Swiss tertiary reference center over a 20-year period.

Materials And Methods: Retrospective cohort study on patients with uveitis aged less than 16 years seen at Jules-Gonin Eye Hospital between 1 January 2000 and 31 December 2019.

Results: Out of 2846 patients with uveitis seen in the Jules-Gonin Eye Hospital Ocular Immune-Infectiology Department, 317 (11. Read More

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Classification criteria for multiple sclerosis-associated intermediate uveitis: Multiple sclerosis uveitis.

Authors:

Am J Ophthalmol 2021 Apr 9. Epub 2021 Apr 9.

the Department of Epidemiology, Baltimore, MD, USA.

Purpose: To determine classification criteria for multiple sclerosis-associated intermediate uveitis.

Design: Machine learning of cases with multiple sclerosis-associated intermediate uveitis and 4 other intermediate uveitides.

Methods: Cases of intermediate uveitides were collected in an informatics-designed preliminary database, and a final database was constructed of cases achieving supermajority agreement on the diagnosis, using formal consensus techniques. Read More

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Classification criteria for syphilitic uveitis.

Authors:

Am J Ophthalmol 2021 Apr 9. Epub 2021 Apr 9.

Members of the SUN Working Group are listed online at ajo.com.

Purpose: To determine classification criteria for syphilitic uveitis DESIGN: Machine learning of cases with syphilitic uveitis and 24 other uveitides.

Methods: Cases of anterior, intermediate, posterior, and panuveitides were collected in an informatics-designed preliminary database, and a final database was constructed of cases achieving supermajority agreement on the diagnosis, using formal consensus techniques. Cases were analyzed by anatomic class, and each class was split into a training set and a validation set. Read More

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Classification criteria for tubercular uveitis.

Am J Ophthalmol 2021 Apr 9. Epub 2021 Apr 9.

the Department of Medicine, Texas A&M University, College Station, TX, USA.

Purpose: To determine classification criteria for tubercular uveitis DESIGN: Machine learning of cases with tubercular uveitis and 14 other uveitides.

Methods: Cases of non-infectious posterior or panuveitis, and of infectious posterior or panuveitis were collected in an informatics-designed preliminary database, and a final database was constructed of cases achieving supermajority agreement on the diagnosis, using formal consensus techniques. Cases were analyzed by anatomic class, and each class was split into a training set and a validation set. Read More

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Classification criteria for Behçet Disease Uveitis.

Am J Ophthalmol 2021 Apr 9. Epub 2021 Apr 9.

Members of the SUN Working Group are listed online at ajo.com.

Purpose: To determine classification criteria for Behçet disease uveitis.

Design: Machine learning of cases with Behçet disease and 5 other panuveitides.

Methods: Cases of panuveitides were collected in an informatics-designed preliminary database, and a final database was constructed of cases achieving supermajority agreement on the diagnosis, using formal consensus techniques. Read More

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Classification criteria for pars planitis.

Am J Ophthalmol 2021 Apr 9. Epub 2021 Apr 9.

the Department of Ophthalmology, Emory University School of Medicine.

Purpose: To determine classification criteria for pars planitis DESIGN: Machine learning of cases with pars planitis and 4 other intermediate uveitides.

Methods: Cases of intermediate uveitides were collected in an informatics-designed preliminary database, and a final database was constructed of cases achieving supermajority agreement on the diagnosis, using formal consensus techniques. Cases were split into a training set and a validation set. Read More

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Classification criteria for sarcoidosis-associated uveitis.

Am J Ophthalmol 2021 Apr 9. Epub 2021 Apr 9.

Members of the SUN Working Group are listed online at ajo.com.

Purpose: To determine classification criteria for sarcoidosis-associated uveitis DESIGN: Machine learning of cases with sarcoid uveitis and 15 other uveitides.

Methods: Cases of anterior, intermediate, and panuveitides were collected in an informatics-designed preliminary database, and a final database was constructed of cases achieving supermajority agreement on the diagnosis, using formal consensus techniques. Cases were analyzed by anatomic class, and each class was split into a training set and a validation set. Read More

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Classification criteria intermediate uveitis, non-pars planitis type.

Am J Ophthalmol 2021 Apr 8. Epub 2021 Apr 8.

the Department of Ophthalmology, Emory University School of Medicine.

Purpose: To determine classification criteria for intermediate uveitis, non-pars planitis type (IU- NPP, also known as undifferentiated intermediate uveitis) DESIGN: : Machine learning of cases with IU-NPP and 4 other intermediate uveitides.

Methods: Cases of intermediate uveitides were collected in an informatics-designed preliminary database, and a final database was constructed of cases achieving supermajority agreement on the diagnosis, using formal consensus techniques. Cases were split into a training set and a validation set. Read More

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Relevance of Brain MRI in Patients with Uveitis: Retrospective Cohort on 402 Patients.

Ocul Immunol Inflamm 2021 Apr 7:1-7. Epub 2021 Apr 7.

Department of Internal Medicine, Hôpital de la Croix Rousse, Hospices Civils de Lyon, Lyon, France.

: To assess the diagnostic value of brain magnetic resonance imaging (bMRI) for the etiological diagnosis of uveitis and to establish predictive factors associated with its advantageous use.: Retrospective study on all patients with uveitis who were referred to our tertiary hospital and who underwent a bMRI between 2003 and 2018.: bMRI was contributive in 19 out of 402 cases (5%), among patients with a contributive bMRI, 68% had neurological signs. Read More

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Association of Dupilumab with Intraocular Inflammation.

Ocul Immunol Inflamm 2021 Apr 7:1-6. Epub 2021 Apr 7.

Retina Group of Washington, Chevy Chase, MD, USA.

: To report four cases of uveitis after treatment with dupilumab for atopic dermatitis.: Retrospective case series.: Data was collected from four patients with inflammation that developed after treatment with dupilumab. Read More

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Epidemiology of pediatric uveitis and associated systemic diseases.

Pediatr Rheumatol Online J 2021 Apr 1;19(1):48. Epub 2021 Apr 1.

Department of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Korea.

Background: The early detection of uveitis associated with systemic inflammatory disease in children is important for proper treatment and prognosis. However, the diagnosis may be delayed because of difficulties in childhood examinations and early minor systemic symptoms. The objective of our study was to identify the pattern of childhood uveitis and investigate the frequency and clinical features of rheumatic diseases in pediatric patients with uveitis. Read More

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Systemic associations of sarcoid uveitis: correlation with uveitis phenotype and ethnicity.

Am J Ophthalmol 2021 Mar 15. Epub 2021 Mar 15.

Royal Victoria Eye and Ear, Melbourne, Australia; Centre for Eye Research Australia, University of Melbourne, Melbourne, Australia.

Purpose: To examine systemic associations of sarcoid uveitis and association with uveitis clinical phenotype and ethnicity.

Design: Retrospective cross-sectional study.

Subjects: 362 subjects with definite or presumed sarcoid uveitis from Moorfields Eye Hospital, Royal Victorian Eye and Ear and Auckland District Health Board. Read More

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Aetiology and clinical characteristics of uveitic glaucoma in Turkish patients.

Int Ophthalmol 2021 Jun 17;41(6):2225-2234. Epub 2021 Mar 17.

University of Health Sciences Turkey, Beyoglu Eye Training and Research Hospital, Bereketzade Street Number: 2, Beyoglu, Istanbul, Turkey.

Purpose: To investigate the types, frequency and clinical profiles of uveitic glaucoma seen at a tertiary care center and also to have an idea about the distribution of uveitic glaucoma types in Turkish population.

Methods: Consecutive case notes of all patients attending a specialized uveitis clinic over a 3-month period were reviewed retrospectively.

Results: One hundred and seven eyes of 96 patients were included. Read More

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Risk of Cataract in Intermediate Uveitis.

Am J Ophthalmol 2021 Mar 10. Epub 2021 Mar 10.

Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA; Department of Ophthalmology, Harvard Medical School, Boston, MA; Department of Ophthalmology, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia; MCM Eye Unit; MyungSung Christian Medical Center (MCM General Hospital) and MyungSung Medical School, Addis Ababa, Ethiopia. Electronic address:

Purpose: To determine the incidence of and predictive factors for cataract in intermediate uveitis.

Design: Retrospective cohort study METHODS: Patients were identified from the Systemic Immunosuppressive Therapy for Eye Diseases (SITE) Cohort Study, in which medical records were reviewed to determine demographic and clinical data of every eye/patient at every visit at five participating United States tertiary care uveitis centers. The primary outcome was development of vision-compromising cataract as defined by a decrease in visual acuity to 20/40 or less, or requiring cataract surgery. Read More

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Multimodal imaging in infectious and noninfectious intermediate, posterior and panuveitis.

Curr Opin Ophthalmol 2021 May;32(3):169-182

Oregon Health and Science University, Portland, Oregon, USA.

Purpose Of Review: Given the heterogeneity of uveitis, markers of inflammation vary from patient to patient. Multimodal imaging has proven itself to be critical for accurate evaluation for disease activity and treatment response in uveitis.

Recent Findings: Ultra-widefield (UWF) fluorescein angiography and autofluorescence (AF) as well as optical coherence tomography angiography (OCTA) have provided insights into disease pathogenesis and monitoring not previously appreciated. Read More

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Use of a Telemedicine Risk Assessment Tool to Predict the Risk of Hospitalization of 496 Outpatients With COVID-19: Retrospective Analysis.

JMIR Public Health Surveill 2021 04 30;7(4):e25075. Epub 2021 Apr 30.

Division of Hospital Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA, United States.

Background: Risk assessment of patients with acute COVID-19 in a telemedicine context is not well described. In settings of large numbers of patients, a risk assessment tool may guide resource allocation not only for patient care but also for maximum health care and public health benefit.

Objective: The goal of this study was to determine whether a COVID-19 telemedicine risk assessment tool accurately predicts hospitalizations. Read More

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Parafoveal Microvascular Alterations in Ocular and Non-Ocular Behҫet's Disease Evaluated With Optical Coherence Tomography Angiography.

Invest Ophthalmol Vis Sci 2021 Mar;62(3)

Uveitis Service, Rotterdam Eye Hospital, Rotterdam, The Netherlands.

Purpose: To compare quantitative optical coherence tomography angiography (OCT-A) measurements of the parafoveal microvasculature in retinal capillary plexuses among Behҫet uveitis (BU) patients, non-ocular Behҫet's disease (NOBD) patients, and healthy volunteers (HVs).

Methods: Sixty-eight subjects were enrolled in this prospective observational cross-sectional study. OCT-A imaging was performed using the Heidelberg Engineering Spectralis OCT. Read More

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Intravenous methylprednisolone induces rapid improvement in non-infectious uveitis: a multicentre study of 112 patients.

Clin Exp Rheumatol 2021 03 5. Epub 2021 Mar 5.

Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Universidad de Cantabria, Santander, Spain.

Objectives: Rapid control of intraocular inflammation in non-infectious uveitis (NIU) is mandatory to avoid irreversible structural and functional damage. In this study, we assessed the efficacy and safety of intravenous methylprednisolone (IVMP) pulses in the treatment of NIU.

Methods: A retrospective case series of 112 patients who received IVMP for the treatment of NIU, either isolated or associated with different underlying diseases, was studied. Read More

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Uveitis intermedia as the initial presentation of a primary lymphoma of the central nervous system.

Arch Soc Esp Oftalmol (Engl Ed) 2021 Feb 24. Epub 2021 Feb 24.

Servicio de Neurología, Hospital Italiano de Buenos Aires, Argentina; Servicio de Oftalmología, Hospital Italiano de Buenos Aires, Argentina; Servicio de Hematología, Hospital Italiano de Buenos Aires, Argentina.

Primary central nervous system lymphoma is one of the most infrequent brain tumours, accounting for 3% of primary central nervous system neoplasms. In addition to its low prevalence, clinical presentation is usually nonspecific, leading to diagnostic delay. Intraocular involvement occurs in 15% of cases, and disease onset in this location is even rarer. Read More

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February 2021

New pharmacotherapy options for noninfectious posterior uveitis.

Int Ophthalmol 2021 Jun 25;41(6):2265-2281. Epub 2021 Feb 25.

Centre for Ophthalmology, University Hospital, 72076, Tuebingen, Germany.

Introduction: Noninfectious inflammation of the posterior eye segment represents an important cause of visual impairment. It often affects relatively young people and causes a significant personal and social impact. Although steroids and nonbiologic- Disease-Modifying Antirheumatic Drugs (nbDMARDs) are effective both in acute and long- lasting diseases, however they are increasingly being replaced by biologic (DMARDs). Read More

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Clinical Course and Treatment Paradigms for JIA-related Uveitis and Pars Planitis Uveitis Using Precise Ocular Investigational Methods.

Klin Monbl Augenheilkd 2021 Apr 19;238(4):458-468. Epub 2021 Feb 19.

Retinal and Inflammatory Eye Diseases, Centre for Ophthalmic Specialized Care (COS), Clinic Montchoisi Teaching Centre, Lausanne, Switzerland.

Purpose: The aim of this study was to report on the disease course and management modalities in patients with juvenile idiopathic arthritis-related uveitis (JIA uveitis) or intermediate uveitis of the pars planitis type (PP) who were followed up using precise ocular investigational techniques.

Methods: This is a retrospective single-centre study. All charts of patients seen in our centre over 15 years (2005 - 2019) with a diagnosis of JIA uveitis or PP were retrieved and analysed for clinical course, severity of inflammation, type of management, and the role played by precise investigational techniques (laser flare photometry [LFP], optical coherence tomography [OCT] and fluorescein angiography [FA]) in therapeutic decisions. Read More

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Review of de novo uveitis in older adults presenting to a large tertiary centre.

Br J Ophthalmol 2021 Feb 17. Epub 2021 Feb 17.

Ophthalmology, Greenlane Clinical Centre, Auckland, New Zealand.

Background/aims: The primary aim of this study was to describe the causes of de novo uveitis in individuals 60 years and older. Secondary objectives were to determine the incidence of intraocular lymphoma and the clinical predictors of lymphoma.

Methods: Retrospective chart review of all subjects presenting to the uveitis service at Auckland District Health Board (Auckland, New Zealand) between January 2006 and October 2020 RESULTS: 686 subjects (900 eyes) were aged ≥60 years at first presentation with uveitis, representing 23. Read More

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February 2021