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J Bras Nefrol 2018 Jul-Sep;40(3):296-300. Epub 2018 Jun 18.

Unidade de Nefrologia e Transplantação Renal, Serviço de Pediatria Médica, Departamento de Pediatria, Hospital de Santa Maria, Centro Académico de Medicina, Universidade de Lisboa, Lisboa, Portugal.

Tubulointerstitial nephritis and uveitis syndrome is a rare and probably underdiagnosed condition. Renal and ocular manifestations may not occur simultaneously, making the diagnosis more difficult. Nephritis may be asymptomatic; therefore, renal function evaluation is essential for diagnosis. Read More

Am J Ophthalmol Case Rep 2018 Jun 8;10:117-118. Epub 2018 Feb 8.

F.I. Proctor Foundation, University of California, San Francisco, United States.

Purpose: To report on a case of uveitis and scleritis resulting as an immune-mediated side effect of cancer immunotherapy with nivolumab and cabiralizumab.

Observations: Bilateral anterior nongranulomatous anterior uveitis and bilateral diffuse anterior and posterior scleritis occurred following the use of combination cancer immunotherapy. The uveitis and scleritis resolved following temporary discontinuation of nivolumab and cabiralizumab as well as systemic prednisone. Read More

Retin Cases Brief Rep 2018 Jan 16. Epub 2018 Jan 16.

Department of Ophthalmology, CHU Saint-Pierre, Université Libre de Bruxelles, Brussels, Belgium.

Purpose: To present a case of frosted branch periphlebitis in a young Armenian patient with familial Mediterranean fever.

Methods: Case report.

Results: A 37-year-old man presented with a unilateral decreased visual acuity and floaters for 4 days on the left eye (LE). Read More

Int Ophthalmol 2018 Dec 21;38(6):2487-2493. Epub 2017 Nov 21.

Department of Uvea, Medical Research Foundation, Sankara Nethralaya, Chennai, 600006, India.

Purpose: To describe clinical manifestations, management and visual outcome in postsurgical sympathetic ophthalmia (SO).

Methods: Retrospective study.

Results: Mean age of the patients was 41. Read More

Invest Ophthalmol Vis Sci 2017 09;58(11):4778-4783

Karl Landsteiner Institute for Retinal Research and Imaging, Department of Ophthalmology, Rudolf Foundation Hospital, Vienna, Austria.

Purpose: To analyze retinal thickness (RT) and choroidal thickness (ChT) changes in patients with unilateral nongranulomatous acute anterior uveitis (AAU) using three-dimensional (3D) 1060-nm optical coherence tomography (OCT).

Methods: Retinal and choroidal thickness maps were statistically analyzed for 24 patients with newly diagnosed unilateral AAU before therapy. A total of 17 patients were followed until resolution of inflammatory activity (twice in the first week, then weekly). Read More

Surv Ophthalmol 2017 May - Jun;62(3):277-285. Epub 2016 Dec 22.

Princess Alexandra Eye Pavilion, Edinburgh, United Kingdom.

Posner-Schlossman syndrome, or glaucomatocyclitic crisis, is a unilateral ocular condition characterized by recurrent attacks of nongranulomatous anterior uveitis and raised intraocular pressure that can result in chronic secondary glaucoma. This relatively rare disease is most likely the result of recurrent cytomegalovirus infection and affects predominantly middle-aged males. Diagnosis is largely clinical, with aqueous and blood sampling aiding the identification of any underlying infectious cause. Read More

Retin Cases Brief Rep 2017 Fall;11(4):348-351

*Dartmouth College, Hanover, New Hampshire; and †Michigan State University, Grand Rapids, Michigan.

Purpose: To describe the development of uveitis and retinal vasculitis in association with pembrolizumab treatment for metastatic uveal melanoma.

Methods: A case report and a brief review of the literature are presented. Information collected and reported include the patient's clinical course, physical examination findings, fluorescein angiogram images, retinal photographs, and her response to treatment. Read More

Optom Vis Sci 2016 06;93(6):647-51

*OD, FAAO †OD New Mexico VA Health Care System, Albuquerque, New Mexico.

Purpose: The incidence of syphilis appears to be increasing in recent years. Although any structure of the eye can be involved in syphilis, isolated unilateral anterior uveitis as an initial sign of the disease is rare. We report a case of ocular syphilis presenting as a mild unilateral, nongranulomatous, anterior uveitis in an otherwise asymptomatic patient. Read More

Ophthalmologica 2016 5;235(1):18-25. Epub 2015 Nov 5.

Department of Ophthalmology at National Defense Medical College, Saitama, Japan.

Purpose: The aim of this study was to compare the outcomes of vitrectomy in granulomatous uveitis and nongranulomatous uveitis insufficiently managed by immunosuppressive therapy.

Methods: Thirty-eight eyes with granulomatous uveitis and 17 eyes with nongranulomatous uveitis that underwent vitrectomy for ocular complications between July 2006 and August 2012 were reviewed retrospectively. Visual acuity and ocular inflammation scores before and 6 months after surgery were compared. Read More

Optom Vis Sci 2015 May;92(5):e97-e105

*OD, DO, MS, FAAO †BA Department of Ophthalmology, Mayo Clinic Health System, Albert Lea, Minnesota (LS, Jr.); and Pacific University College of Optometry, Forest Grove, Oregon (LG).

Purpose: To present a case of neovascular age-related macular degeneration treated with aflibercept intravitreal injections after bilateral bevacizumab injections, administered on separate dates, resulted in bilateral iritis.

Case Report: A 73-year-old woman with a previous history of two episodes of nongranulomatous iritis in her right eye that was believed to be associated with her systemic diagnosis of rheumatoid arthritis was treated with intravitreal bevacizumab injections for bilaterally occurring neovascular age-related macular degeneration. Initial bevacizumab injections in each eye administered sequentially over a week's time resulted in immediate-onset nongranulomatous iritis in each eye. Read More

J Ophthalmic Inflamm Infect 2015 13;5. Epub 2015 Feb 13.

Department of Pediatric Rheumatology, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey.

Background: Tubulointerstitial nephritis and uveitis [TINU] syndrome is a rare disorder that may also be underdiagnosed. Patients with TINU syndrome typically present with an acute bilateral nongranulomatous anterior uveitis following symptoms of systemic illness.

Findings: We report the case of a 15-year-old girl who presented with acute granulomatous iridocyclitis and was diagnosed with TINU syndrome based on renal biopsy findings. Read More

Clin Ophthalmol 2014 26;8:2383-9. Epub 2014 Nov 26.

Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.

Purpose: To investigate the characteristics of uveitic glaucoma (UG) and evaluate surgical treatments.

Methods: This study examined a retrospective, nonrandomized comparative interventional case series of 105 UG patients (141 eyes) followed between April 1, 2001 and July 30, 2014 at the outpatient clinic of Tohoku University Hospital. The study group included 47 patients (47 eyes) who underwent glaucoma surgery: trabeculectomy, trabeculotomy, and trabectome surgery. Read More

Ocul Immunol Inflamm 2015 Aug 24;23(4):311-319. Epub 2014 Jul 24.

a Department of Ophthalmology , College of Medicine, King Saud University , Riyadh , Saudi Arabia.

Purpose: To investigate the referral patterns and diagnosis of uveitis in a university-based tertiary referral center in Riyadh, Saudi Arabia.

Methods: We retrospectively reviewed the medical records of 642 patients (1220 eyes).

Results: There were 295 (46%) males and 347 (54%) female patients, with a mean age of 36. Read More

Am J Ophthalmol 2014 Sep 27;158(3):637-43.e1. Epub 2014 May 27.

Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland.

Purpose: To describe the clinical presentation of uveitis with coincident onset of raised and indurated tattooed skin.

Design: Case series.

Methods: Seven consecutive patients were evaluated at a tertiary ophthalmologic facility with coincident uveitis and cutaneous tattoo induration over an 18-month period. Read More

Ocul Immunol Inflamm 2014 Jun 24;22(3):236-8. Epub 2014 Feb 24.

Department of Medicine, Division of General Internal Medicine, The Johns Hopkins University School of Medicine , Baltimore, Maryland , USA .

Purpose: To describe a case of Rosai-Dorfman-associated sclerouveitis in an HIV-infected patient.

Design: Case report.

Methods: A 49-year-old man with HIV had bilateral eye pain, redness, photophobia, and multiple systemic complaints. Read More

Saudi J Ophthalmol 2013 Oct 19;27(4):295-8. Epub 2013 Jun 19.

Anterior Segment and Uveitis Division, Ophthalmology Department, Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia.

A 34-year-old female with Usher syndrome, but no family history of similar illness, presented with complaints of vision reduction, redness, and photophobia. Biomicroscopic examination showed mildly injected conjunctivae bilateral, small, round keratic precipitates; bilateral +2 cells with no flare reaction in the anterior chamber; and bilateral posterior subcapsular cataracts. No associated posterior synechiae, angle neovascularization, or iris changes were detected; normal intraocular pressures were obtained. Read More

Dig Dis 2013 6;31(2):229-32. Epub 2013 Sep 6.

Department of Ophthalmology, Miguel Servet University Hospital, Instituto de Investigación Sanitaria de Aragón IIS-A, Zaragoza, Spain.

Extraintestinal manifestations are common in inflammatory bowel disease (IBD), being reported in over 25% of patients. Ocular complications of IBD occur in around 10% of cases, but may precede systemic symptoms and are usually nonspecific. Complications of therapy, such as cataracts or glaucoma from steroid use or keratoconjunctivitis sicca related to 5-aminosalicylic acid medications, may also involve the eyes. Read More

Ocul Immunol Inflamm 2013 Dec 19;21(6):478-85. Epub 2013 Aug 19.

John A. Moran Eye Center, Salt Lake City , Utah , USA .

Juvenile idiopathic arthritis (JIA) is the most common childhood rheumatic disease and the most prevalent systemic disorder in children with uveitis. The risk of developing uveitis is the greatest among patients with oligoarticular onset of disease. Clinical features of JIA-associated uveitis (JIAU) are nongranulomatous inflammation, anterior in location, insidious at onset, chronic course, and frequently asymptomatic in the absence of ocular structural complications. Read More

Ocul Immunol Inflamm 2013 Oct 3;21(5):337-50. Epub 2013 Jun 3.

Department of Ophthalmology, Istanbul Faculty of Medicine, Istanbul University , Istanbul , Turkey .

The diagnosis of Behçet disease is clinical and based on the presence of characteristic ocular and systemic inflammatory manifestations. Patients may present with anterior, posterior, or panuveitis in one or both eyes. The differential diagnosis includes a variety of infectious and noninfectious causes of acute nongranulomatous anterior uveitis, intermediate uveitis, occlusive retinal vasculitis, focal or multifocal retinitis, and necrotizing retinitis. Read More

J Ophthalmic Inflamm Infect 2013 Feb 11;3(1):33. Epub 2013 Feb 11.

Hospital de Olhos Santa Luzia, Estrada do Encanamento 909, CEP 52070-000, Recife-Pernambuco, Brazil.

Background: This paper reports the case of a pleomorphic manifestation of syphilis, a reemerging sexually transmitted disease.

Findings: A 51-year-old male presented with bilateral nongranulomatous anterior uveitis associated with an isolated syphilitic chancre of the tongue that was successfully treated with parenteral benzathine penicillin.

Conclusion: Syphilis has the potential to lead to any type of intraocular inflammation. Read More

J Ophthalmic Inflamm Infect 2013 Feb 11;3(1):37. Epub 2013 Feb 11.

Laboratory of Immunology, National Eye Institute, National Institutes of Health, 10 Center Dr, 10/10N112, Bethesda, MD, 20892, USA.

Background: The purpose of this study was to report the case of a patient with bilateral panuveitis who was found to have a rarely reported intraocular fungus, Aspergillus conicus. A 40-year-old man presented with gradual vision loss in both eyes. He had bilateral anterior uveitis, granulomatous vitritis with a preretinal granuloma in the right eye, and nongranulomatous vitritis with two quadrants of chorioretinal scarring in the left. Read More

Korean J Ophthalmol 2013 Feb 18;27(1):58-60. Epub 2012 Dec 18.

Department of Ophthalmology, Kyungpook National University School of Medicine, Daegu, Korea.

A 32-year-old male who had infective endocarditis complained of photophobia and blurred vision in both eyes. Biomicroscopic examination and fundus examination revealed anterior chamber reaction, vitritis, optic disc swelling, and Roth spots. He was diagnosed with bilateral nongranulomatous uveitis and treated with topical steroid eye drops and posterior sub-Tenon injection of triamcinolone. Read More

Ocul Immunol Inflamm 2013 ;21(1):44-6

Aim: To report 2 cases of idiopathic anterior uveitis with coexistent myasthenia gravis.

Materials And Methods: Retrospective case reports.

Results: A 60-year-old male and a 40-year-old male presented with chronic nongranulomatous anterior uveitis of unknown etiology. Read More

Invest Ophthalmol Vis Sci 2013 Jan 9;54(1):258-65. Epub 2013 Jan 9.

Center for Ophthalmic Optics and Lasers, Casey Eye Institute and Department of Ophthalmology, Oregon Health and Science University, Portland, Oregon 97239, USA.

Purpose: To quantify cells in the ocular anterior chamber (AC) by optical coherence tomography (OCT).

Methods: A time-domain anterior segment OCT system was used to image latex microsphere suspensions in vitro and the AC of uveitis and normal subjects in vivo. The OCT scan pattern, consisting of 2- and 4-mm-diameter concentric circular scans, was divided into central, superior, and inferior regions. Read More

Ocul Immunol Inflamm 2012 Oct;20(5):375-7

Purpose: To describe IgG4-positive sclerosing orbital inflammation with prominent conjunctival and scleral involvement.

Design: Case report.

Methods: Clinical, radiologic, and pathologic correlation. Read More

Arch Ophthalmol 2012 Nov;130(11):1389-94

OBJECTIVE To describe the etiology and outcome of patients with simultaneous-onset nongranulomatous bilateral acute anterior uveitis. METHODS The medical records of patients who presented to a single tertiary care center with simultaneous-onset nongranulomatous bilateral acute anterior uveitis between January 1990 and May 2010 were retrospectively reviewed; the clinical presentation, results of diagnostic testing, and outcome data are described. RESULTS A total of 4288 new patients with uveitis were evaluated by the Uveitis Service at the University of Illinois at Chicago Eye and Ear Infirmary between January 1990 and May 2010. Read More

Ocul Immunol Inflamm 2011 Apr;19(2):139-44

School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.

Acute anterior uveitis (AAU) is the most common form of uveitis, accounting for approximately 90% of all cases. Half of all cases of AAU are HLA-B27 positive. The disease is typically acute in onset, unilateral, nongranulomatous inflammation involving the iris and ciliary body, with a tendency to recurrent attacks. Read More

J Rheumatol 2011 Feb 1;38(2):325-30. Epub 2010 Dec 1.

Pregonero 161, Frac. Colina del Sur, CP 01430, México, DF, Mexico.

Objective: Our aim is to describe the frequency of uveitis associated with rheumatic inflammatory autoimmune diseases (RIAD) in adult patients admitted to the Rheumatology Department at a tertiary-care hospital in Mexico City. We also describe the clinical features, seasonal distribution, treatment, and ocular complications associated with this disease.

Methods: We reviewed 1332 charts of patients with RIAD and selected those that had a diagnosis of uveitis. Read More

J Fr Ophtalmol 2011 Jan 26;34(1):24-9. Epub 2010 Nov 26.

Service d'ophtalmologie, hôpital Edouard-Herriot, CHU de Lyon, hospices civils de Lyon, université Claude-Bernard Lyon-I, 5, place d'Arsonval, 69437 Lyon cedex 03, France.

Purpose: To investigate the possible association between cytomegalovirus (CMV) infection and Posner-Schlossman syndrome using PCR. To evaluate the clinical effect of valganciclovir treatment.

Patients And Methods: Patients with anterior uveitis associated with suspected Posner-Schlossman syndrome had their aqueous humor prospectively analyzed for viral deoxyribonucleic acid by HXFL4 gene detection using quantitative real-time PCR. Read More

Ocul Immunol Inflamm 2010 Dec 1;18(6):485-7. Epub 2010 Oct 1.

The Francis I. Proctor Foundation and Department of Ophthalmology, University of California-San Francisco, San Francisco, California 4143-0730, USA.

Purpose: To report a case of anterior uveitis associated with high-dose cytosine arabinoside (Ara-C) treatment.

Design: Observational case report.

Methods: A 14-year-old girl was seen for pain, redness, and photophobia shortly after finishing a cycle of high-dose Ara-C. Read More

Cornea 2010 Jun;29(6):650-4

Ophthalmic Research Center of Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Purpose: To specify confocal scan features of keratic precipitates (KPs) in uveitic eyes of various etiologies.

Methods: Confocal scan was performed on 129 eyes of 93 patients with different types of uveitis to characterize the morphologic features of KPs. The study included Fuchs heterochromic iridocyclitis (FHIC) in 50 eyes, idiopathic granulomatous uveitis in 27, herpetic anterior uveitis in 10, pars planitis associated with endotheliitis in 9, Vogt-Koyanagi-Harada syndrome in 8, multiple sclerosis-related uveitis in 7, sarcoidosis in 3, acute anterior uveitis not associated with HLA B27 in 3, acute retinal necrosis in 2, psoriatic uveitis in 2, chronic endophthalmitis in 2, sclerouveitis in 2, HLA B27-associated anterior uveitis in 2, sympathetic ophthalmia in 1, and toxoplasmosis in 1. Read More

Middle East Afr J Ophthalmol 2009 Oct;16(4):219-24

Department of Ophthalmology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey.

Behçet's disease is a multisystem inflammatory disorder that is most common in countries along the ancient "Silk Road". The eye is the most commonly involved vital organ in Behçet's patients and the typical form of involvement is a relapsing remitting panuveitis and retinal vasculitis. Uveitis is the initial manifestation of the disease in 10-15% of the patients. Read More

Ocul Immunol Inflamm 2010 Apr;18(2):116-20

Massachusetts Eye Research and Surgery Institution, Cambridge, Massachusetts 02142, USA.

Objective: To investigate oral nonsteroidal anti-inflammatory drug (NSAID) therapy in the prevention of recurrences of uveitis in patients with recurrent nongranulomatous, idiopathic, or HLA-B27-associated acute anterior uveitis (AAU).

Methods: Retrospective case series of 59 patients with recurrent AAU treated with celecoxib or diflunisal.

Results: The average duration of NSAID therapy was 21. Read More

J Pediatr Ophthalmol Strabismus 2009 Oct 2. Epub 2009 Oct 2.

A 10-year-old boy with biopsy-proven systemic mastocytosis presented with bilateral nongranulomatous anterior uveitis associated with high intraocular pressure. Anterior chamber paracentesis was performed for cytological evaluation, which demonstrated monocytes and macrophages but no evidence of mast cells. His uveitis was partially controlled with frequent topical steroid drops and weekly oral methotrexate therapy. Read More

Ocul Immunol Inflamm 2009 Jan-Feb;17(1):11-6

The Eye Center, Riyadh, Saudi Arabia.

Purpose: The main purpose of this study was to determine the causes of uveitis at the Eye Center in Saudi Arabia.

Methods: A retrospective review. The causes of uveitis were analyzed according to various patient characteristics. Read More

Can J Ophthalmol 2008 Dec;43(6):652-7

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ont.

Background: To evaluate the cost-effectiveness of anterior uveitis investigation by Canadian ophthalmologists and to assess the role of implementing national clinical guidelines for such investigation.

Methods: Based on data extracted from the Canadian National Uveitis Survey (CNUS, 2007 version), the cost of investigating a patient with anterior uveitis, according to current practice patterns of Canadian ophthalmologists, was determined and grouped across 4 clinical scenarios: (i) nongranulomatous anterior uveitis in an adult, (ii) granulomatous anterior uveitis in an adult, (iii) granulomatous anterior uveitis with suspected sarcoidosis in an adult or a child, and (iv) nongranulomatous anterior uveitis in a child. Similarly, the cost of investigating a patient with anterior uveitis as per published evidence-based guidelines was determined and compared with the current practice pattern using a cost-minimization model, sensitivity analyses, and Monte Carlo simulations. Read More

J AAPOS 2008 Dec 30;12(6):608-10. Epub 2008 Aug 30.

Department of Ophthalmology, Nelson R. Mandela School of Medicine University of KwaZulu-Natal, Durban, South Africa.

Purpose: To describe the ocular inflammatory manifestations and clinical characteristics of children with Human Immunodeficiency Virus (HIV)-associated arthritis.

Methods: A retrospective review of the charts of children with chronic uveitis and HIV-associated arthritis seen between June 2004 and September 2006 at Inkosi Albert Luthuli Central Hospital, Durban, South Africa. The following data were analyzed: age at presentation, gender, race/ethnicity, rheumatologic problems, uveitic diagnosis, laboratory findings, and ocular complications. Read More

Ocul Immunol Inflamm 2008 May-Jun;16(3):107-8

Department of Ophthalmology, California Pacific Medical Center, San Francisco, California, USA.

Purpose: To describe a patient with HLA-B27-associated anterior uveitis who developed hypotony maculopathy.

Methods: Visual acuity, biomicroscopic slit-lamp examination, and fluorescein angiogram.

Results: Following an episode of acute anterior nongranulomatous HLA-B27-associated uveitis, the patient developed decreased vision, choroidal folds, optic disc edema, and a serous exudative detachment characteristic of hypotony maculopathy. Read More

Ophthalmology 2008 Oct 21;115(10):1833-6. Epub 2008 May 21.

Department of Ophthalmology, Keck School of Medicine of the University of Southern California, A Ray Irvine Ocular Pathology Laboratory, the Doheny Eye Institute, Los Angeles, California 90033, USA.

Purpose: To provide a detailed immunohistochemical analysis of juvenile idiopathic arthritis (JIA)-associated anterior uveitis.

Design: Interventional case report.

Participant: One patient. Read More

Ophthalmology 2008 Feb 10;115(2):312-318.e4. Epub 2007 Aug 10.

Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.

Purpose: To characterize the clinical features of Behçet's disease in Chinese patients.

Design: Retrospective noncomparative case series.

Participants: Seven hundred seventy-five eyes of 437 patients with Behçet's disease initially examined from August, 1995, through June, 2006. Read More

Am J Ophthalmol 2007 Oct 9;144(4):552-6. Epub 2007 Aug 9.

Department of Ocular Microbiology, Aravind Eye Hospital, Madurai, India.

Purpose: To study the range of ocular symptoms in a cohort of patients with chikungunya infection.

Design: Retrospective, observational case series.

Methods: Patients attending a tertiary eye care hospital in South India were included in the study. Read More

Ophthalmology 2007 Mar 21;114(3):606-14. Epub 2006 Nov 21.

Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.

Purpose: To characterize the clinical features of Vogt-Koyanagi-Harada syndrome (VKH) in Chinese patients.

Design: Retrospective noncomparative case series.

Participants: A total of 410 consecutive VKH patients examined from August 1995 to April 2005. Read More

Am J Ophthalmol 2006 Mar;141(3):498-507

Uveitis Service, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Aravind Medical Research Foundation, 1 Anna Nagar, Madurai, Tamil Nadu 625-020, India.

Purpose: Clinical and histopathologic documentation of sympathetic ophthalmia (SO) development in eyes with postoperative bacterial endophthalmitis.

Design: Observational case series; retrospective clinicopathologic study.

Methods: All patients who presented with a clinical diagnosis of SO during 2002 to 2004 were included in the study. Read More

Acta Clin Belg 2005 Sep-Oct;60(5):270-5

Afdeling Oogheelkunde, Universitair Ziekenhuis, Gent.

The purpose of this article is to outline the interaction between ophthalmologists and internists in the management of uveitis. Two issues will be addressed: 1) which strategies should the internist follow when asked to investigate a case of uveitis; and 2) in which systemic diseases should the internist order an ocular examination to rule out intraocular inflammation. The modern approach to the diagnosis of uveitis is based on the naming-meshing system popularized by Smith and Nozik. Read More

Ophthalmology 2005 Jul;112(7):1287-92

Ocular Immunology and Uveitis Foundation, Boston, Massachusetts, USA.

Objective: To analyze demographics, anatomic data, diagnoses, systemic associations, and visual outcomes of pediatric patients in a large tertiary eye center.

Design: Retrospective cohort study.

Methods: The records of 1242 patients with uveitis referred to the Ocular Immunology and Uveitis Service of the Massachusetts Eye and Ear Infirmary (MEEI) from 1985 to 2003 were reviewed retrospectively. Read More

Ophthalmology 2005 Feb;112(2):313-8

Department of Ophthalmology, King Fahad Central Hospital, Jizan, Saudi Arabia.

Objective: To report ocular complications of Rift Valley fever (RVF) during its first reported outbreak in southwest Saudi Arabia in autumn 2000.

Design: Cross-sectional study of patients in a referral hospital.

Participants: One hundred forty-three consecutive patients with confirmed RVF serologic test results and ocular lesions were enrolled in the study. Read More

Ocul Immunol Inflamm 2004 Dec;12(4):297-310

Ocular Inflammatory and Uveitis Service, Ophthalmology Department and Ophthalmic Research Center, Labbafinejad Medical Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran.

Purpose: To identify the distribution and characteristics of new uveitis referrals to a tertiary eye care center in Tehran.

Methods: A three-year prospective study was carried out to obtain information on 544 new patients referred with uveitis. A complete ophthalmologic examination was performed in all cases; a routine set of tests and an additional battery of directed workup were conducted when indicated. Read More

Am J Ophthalmol 2004 Nov;138(5):878-9

Department of Ophthalmology, University of California, San Francisco, California, USA.

Purpose: To report a case of Propionibacterium acnes endophthalmitis following uncomplicated cataract extraction with bacterial sequestration in a preexisting Molteno's drainage implant.

Design: Interventional case report.

Methods: A 7-year-old girl with congenital glaucoma and a preexisting Molteno's drainage implant developed anterior nongranulomatous uveitis 4 months following cataract surgery. Read More

Optom Vis Sci 2004 Aug;81(8):578-85

NOVA Southeastern University, College of Optometry, 1750 NE 167th Street, North Miami Beach, FL 33162, USA.

Purpose: Two cases of poststreptococcal uveitis are presented. One patient developed nongranulomatous anterior uveitis (case 1). A second patient developed nongranulomatous anterior uveitis followed by granulomatous uveitis with concurrent choroiditis, retinal pigment epithelial detachment, and cystoid macular edema (case 2). Read More

J Cataract Refract Surg 2003 Nov;29(11):2242-3

Casey Eye Institute, Department of Ophthalmology, Oregon Health and Science University, Portland, OR 97401, USA.

A 72-year-old man with long-standing bilateral glaucoma became refractory to levobunolol ophthalmic solution therapy after many years. Brimonidine was prescribed, but the patient developed a hypersensitivity several months later that was treated with loteprednol ophthalmic suspension. Bimatoprost was initiated 2 weeks later. Read More