428 results match your criteria Uveitis Anterior Granulomatous


Bilateral uveitis associated with nivolumab therapy for metastatic non-small cell lung cancer.

Am J Ophthalmol Case Rep 2020 Jun 7;18:100691. Epub 2020 Apr 7.

Bascom Palmer Eye Institute And, University of Miami Miller School of Medicine 900 NW 17th Street, Miami, FL, 33136, USA.

Purpose: To report a case of bilateral uveitis secondary to intravenous nivolumab therapy in a patient with stage IV non-small cell lung cancer.

Observations: A 53-year-old male with stage IV non-small cell lung cancer presented with gradual onset of blurry vision in the left eye for nine days after completion of the first cycle of intravenous nivolumab chemotherapy. At initial presentation, best-corrected visual acuity was 20/25 in the right eye and 20/30 in the left eye. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168346PMC

A case of adult-onset tubulointerstitial nephritis and uveitis syndrome presenting with granulomatous panuveitis.

Taiwan J Ophthalmol 2020 Jan-Mar;10(1):66-70. Epub 2020 Mar 4.

Department of Pathology, Hacettepe University, Ankara, Turkey.

The tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare disorder that is probably underdiagnosed in clinical practice. Ocular involvement in TINU syndrome not only presents with the nongranulomatous anterior uveitis in 80% of patients but also manifests as intermediate, posterior, or panuveitis. This case report mentions an adult male patient who presented with granulomatous iridocyclitis with panuveitis and mild renal insufficiency. Read More

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http://dx.doi.org/10.4103/tjo.tjo_33_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158930PMC

[Anterior Uveitis: Clinic, Diagnostic Procedure and Treatment Options].

Klin Monbl Augenheilkd 2020 Apr 17. Epub 2020 Apr 17.

Anterior uveitis involves inflammation of the iris and/or ciliary body and is the most common intraocular inflammation in ophthalmological practice. It can be attributed to an infectious or immune-mediated genesis or be associated with systemic diseases. Anamnesis and (guiding) findings during the slit lamp examination often already provide important information on pathogenesis and thus on further diagnostic clarification and therapy. Read More

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http://dx.doi.org/10.1055/a-1148-2875DOI Listing
April 2020
0.665 Impact Factor

Clinical Profile in Genetically Proven Blau Syndrome: A Case Series from South India.

Ocul Immunol Inflamm 2020 Apr 15:1-7. Epub 2020 Apr 15.

Department of Pediatric Rheumatology, Manipal Hospitals; Indira Gandhi Institute of Child Health Sciences, Bengaluru, India.

: To report the clinical profile of genetically proven Blau syndrome in seven cases from a single center in South India.: Retrospective case series: There were four females and three males. All cases had a history of skin and joint involvement of varying severity. Read More

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http://dx.doi.org/10.1080/09273948.2020.1746353DOI Listing

An Algorithm for the Diagnosis of Behçet Disease Uveitis in Adults.

Ocul Immunol Inflamm 2020 Apr 14:1-10. Epub 2020 Apr 14.

Division of Rheumatology, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.

: To develop an algorithm for the diagnosis of Behçet's disease (BD) uveitis based on ocular findings.: Following an initial survey among uveitis experts, we collected multi-center retrospective data on 211 patients with BD uveitis and 207 patients with other uveitides, and identified ocular findings with a high diagnostic odds ratio (DOR). Subsequently, we collected multi-center prospective data on 127 patients with BD uveitis and 322 controls and developed a diagnostic algorithm using Classification and Regression Tree (CART) analysis and expert opinion. Read More

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http://dx.doi.org/10.1080/09273948.2020.1736310DOI Listing
April 2020
1.440 Impact Factor

Viral Kerato-Uveitis with Choroidal Vitiligo.

Ocul Immunol Inflamm 2020 Apr 7:1-4. Epub 2020 Apr 7.

Department of Cornea and Refractive Surgery, Narayana Nethralaya, Bangalore, India.

: To describe unusual fundus findings in typical varicella zoster (VZV) kerato-uveitis.: Observational, retrospective case study of five patients diagnosed with VZV kerato-uveitis.: Four out of five cases had a history of typical herpes zoster ophthalmicus skin rash over the forehead. Read More

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http://dx.doi.org/10.1080/09273948.2020.1741649DOI Listing
April 2020
1.440 Impact Factor

Patterns of Uveitis in Egypt.

Ocul Immunol Inflamm 2020 Feb 18:1-10. Epub 2020 Feb 18.

Department of Ophthalmology at Faculty of Medicine, Cairo University, Giza, Egypt.

: To investigate the clinical patterns of uveitis patients presenting to the uveitis clinic at Cairo University hospitals.: A retrospective study was conducted on 313 cases of uveitis from May 2015 to May 2017. Patients had detailed ocular and medical examinations. Read More

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http://dx.doi.org/10.1080/09273948.2020.1714060DOI Listing
February 2020

Anterior chamber granuloma: conservative treatment versus surgical intervention.

Acta Ophthalmol 2020 Jan 23. Epub 2020 Jan 23.

Department of Ophthalmology, Faculty of Medicine, Cairo University, Cairo, Egypt.

Purpose: A distinct pattern of granulomatous anterior uveitis, with white anterior chamber (AC) granuloma, has been reported in certain endemic areas. The aim of this work was to compare the outcome of conservative treatment to surgical intervention for the treatment of large AC granulomas presenting with moderate-severe anterior uveitis. The secondary outcome is ultrasound biomicroscopy (UBM) characterization of AC granulomas. Read More

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http://dx.doi.org/10.1111/aos.14355DOI Listing
January 2020

Diagnostic dilemma: Unilateral panuveitis mimicking endophthalmitis in very severe HLA B27-associated uveitis.

Am J Ophthalmol Case Rep 2020 Mar 7;17:100589. Epub 2020 Jan 7.

National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore.

Purpose: To report a case of a 28-years-old male who presented with a worsening unilateral panuveitis after intensive topical steroid therapy which resulted in a diagnostic and treatment dilemma as to whether the patient should be treated as for infective endophthalmitis despite no immediate known infective risk factors.

Observations: A patient presented initially with unilateral non-granulomatous acute anterior uveitis which worsened after being started on intensive steroid therapy, developing fibrinous panuveitis. The rapid worsening of inflammation and vision deterioration despite being on intensive steroid therapy resulted in the patient subsequently being treated as for infective endophthalmitis. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965704PMC

Presumed Intraocular Tuberculosis Manifesting as Unilateral Iris Granuloma.

Ocul Immunol Inflamm 2020 Jan 16:1-4. Epub 2020 Jan 16.

Smt Kannuri Santhamma Vitreoretinal Services, KallamAnji Reddy Campus, L.V. Prasad Eye Institute, Hyderabad, India.

Ocular tuberculosis can manifest in a wide variety of clinical presentations. The prevalence is higher in endemic areas as a cause of granulomatous uveitis. While posterior segment manifestations are well known, anterior segment granulomas alone are relatively rare. Read More

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http://dx.doi.org/10.1080/09273948.2019.1699578DOI Listing
January 2020

[Uveitis: Diagnosis and work-up].

Authors:
C Bonnet A Brézin

J Fr Ophtalmol 2020 Feb 5;43(2):145-151. Epub 2019 Dec 5.

Pôle de Paris, service d'ophtalmologie, hôpital Cochin, université Paris Descartes, 27, rue du Faubourg St Jacques, 75014 Paris, France.

Uveitis is an inflammation of the uveal tissue: iris, ciliary body and choroid. The annual incidence of uveitis in France is low (17/100,000), but visual and therapeutic consequences may be severe. Etiologic investigation is thus a fundamental step in the management of any uveitis. Read More

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http://dx.doi.org/10.1016/j.jfo.2019.03.038DOI Listing
February 2020

Severe Hypotony Maculopathy in Anterior Uveitis Associated with Hodgkin Lymphoma.

Ocul Immunol Inflamm 2019 Oct 24:1-5. Epub 2019 Oct 24.

Department of Ophthalmology, IRCCS Ospedale San Raffaele, University Vita-Salute San Raffaele , Milan , Italy.

: To describe the clinical course and management of anterior uveitis complicated by ocular hypotony associated with Hodgkin lymphoma. : Case report. : Chart and multimodal imaging review, including ultrasound biomicroscopy, widefield fundus pictures, fundus autofluorescence, fluorescein angiography, and indocyanine green angiography. Read More

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http://dx.doi.org/10.1080/09273948.2019.1668952DOI Listing
October 2019

A sarcoidosis-lymphoma syndrome revealed by hypopituitarism.

Endocrinol Diabetes Metab Case Rep 2019 Sep 27;2019. Epub 2019 Sep 27.

Departments of Endocrinology and Nutrition, Université catholique de Louvain, Cliniques Universitaires Saint-Luc, Brussels, Belgium.

Summary: A 26-year-old woman presented with persistent headache and tiredness. Biological investigations disclosed a moderate inflammatory syndrome, low PTH-hypercalcemia and complete anterior hypopituitarism. A magnetic resonance imaging (MRI) of the pituitary gland was performed and revealed a symmetric enlargement with a heterogeneous signal. Read More

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http://dx.doi.org/10.1530/EDM-19-0091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765315PMC
September 2019
3 Reads

Case Report: Bilateral Granulomatous Anterior Uveitis in HIV-patient with Disseminated (penicilliosis) Infection.

Ocul Immunol Inflamm 2019 Oct 2:1-3. Epub 2019 Oct 2.

Department of Ophthalmology, Faculty of Medicine, Chiang Mai University , Chiang Mai , Thailand.

We report on a 22-years-old Thai male patient with congenital HIV infection. Due to his non-adherence to antiretroviral treatment he developed disseminated infection and was treated with intravenous amphotericin B. Despite this treatment, he presented with bilateral granulomatous anterior uveitis. Read More

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http://dx.doi.org/10.1080/09273948.2019.1657468DOI Listing
October 2019

Tocilizumab in refractory juvenile idiopathic arthritis with associated uveitis: a case report.

Acta Reumatol Port 2019 Apr-Jun;44(2):151-154

Centro Hospitalar Vila Nova de Gaia/Espinho.

Introduction: We report a 9-year follow-up of a child with refractory juvenile idiopathic arthritis (JIA) with associated uveitis in which tocilizumab proved to be effective in achieving disease control.

Case Report: A 16-month child was diagnosed with JIA and at the age of 3 developed bilateral non-granulomatous anterior uveitis. Throughout the follow-up, the patient presented frequent joint and ocular flares. Read More

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February 2020
4 Reads
0.831 Impact Factor

Bilateral granulomatous uveitis in an elderly female.

Indian J Ophthalmol 2019 09;67(9):1391

Department of Uveitis and Ocular Inflammation, Vittala International Institute of Ophthalmology and Prabha Eye Clinic and Research Centre, Bengaluru, Karnataka, India.

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http://dx.doi.org/10.4103/ijo.IJO_1427_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727697PMC
September 2019

Extranodal Rosai-Dorfman of the Pancreas Presents with Bilateral Granulomatous Anterior Uveitis.

Ocul Oncol Pathol 2019 Jun 25;5(4):229-233. Epub 2018 Oct 25.

Emory University School of Medicine, Assistant Professor of Ophthalmology, Section of Vitreoretinal Surgery and Diseases, Section of Uveitis and Vasculitis, Atlanta, Georgia, USA.

Background/aims: To report a case of a 65-year-old female who presented with bilateral anterior granulomatous uveitis, which led to the diagnosis of Rosai-Dorfman Disease (RDD) and the discovery of an associated pancreatic mass.

Methods: This is a retrospective case report of a single patient.

Results: A 65-year-old African American Female received a full workup for bilateral anterior granulomatous uveitis and was found to have a pancreatic mass on imaging. Read More

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http://dx.doi.org/10.1159/000493639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615342PMC
June 2019
3 Reads

Lyme-associated uveitis: Clinical spectrum and review of literature.

Eur J Ophthalmol 2019 Jun 26:1120672119856943. Epub 2019 Jun 26.

1 Department of Ophthalmology, Croix-Rousse University Hospital, Hospices Civils de Lyon, University of Lyon I, Lyon, France.

Background: Clinical presentation of Lyme-associated uveitis is poorly described. We reported here a case series of seven patients with uveitis related to Lyme disease and a review of the literature.

Methods: A retrospective study in our university hospital between 1 May 2003 and 31 July 2016 on 1006 uveitis patients and review of Pubmed library. Read More

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http://dx.doi.org/10.1177/1120672119856943DOI Listing
June 2019
14 Reads

Œdème papillaire isolé révélant une sarcoïdose oculaire: Isolated papillary edema revealing ocular sarcoidosis.

Pan Afr Med J 2019 20;32:132. Epub 2019 Mar 20.

Service d'Ophtalmologie, Hôpital Militaire d'Instruction Mohammed V, Faculté de Médecine et de Pharmacie Université Mohammed V, Rabat, Maroc.

Sarcoidosis is a multisystem granulomatous disorders of unknown cause, characterised by the presence of epithelioid granulomas and giant-cell granulomas without caseous necrosis. Ocular sarcoidosis mainly manifests as bilateral anterior granulomatous uveitis. The involvement of the posterior segment in patients with ocular sarcoidosis is rare and manifests as periphlebitis or choroidal invasion. Read More

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http://dx.doi.org/10.11604/pamj.2019.32.132.18253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560945PMC
July 2019
7 Reads

Granuloma-like formation in deeper retinal plexus in ocular sarcoidosis.

Clin Ophthalmol 2019 27;13:895-896. Epub 2019 May 27.

Department of Ophthalmology, Tokyo Medical University, Tokyo 160-0023, Japan.

Sarcoidosis is a multi-system disease characterized by the presence of non-caseating epithelioid granulomas in affected tissues and the most frequent cause of noninfectious uveitis in Japan. Ocular manifestations of sarcoid uveitis vary enormously and commonly characterized by granulomatous anterior uveitis, intermediate uveitis, and posterior uveitis such as retinal periphlebitis, choroiditis, optic nerve granuloma and papillitis. However, case reports of multiple granuloma formation related to sarcoid uveitis is uncommon. Read More

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http://dx.doi.org/10.2147/OPTH.S200519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549785PMC
May 2019
6 Reads

Feline Ocular Mycobacteriosis: Clinical Presentation, Histopathological Features, and Outcome.

Vet Pathol 2019 09 27;56(5):749-760. Epub 2019 May 27.

2 The Royal (Dick) School of Veterinary Studies and The Roslin Institute, University of Edinburgh, Midlothian, UK.

This study describes clinical and histopathological features, treatment, and outcome of cats diagnosed with ocular mycobacteriosis. Cases diagnosed from 2012 to 2017 were reviewed for (a) histopathological evidence of ocular (pyo)granulomatous inflammation containing acid-fast bacilli with mycobacterial morphology, (b) positive mycobacterial culture and/or mycobacterial DNA identified by polymerase chain reaction of ocular tissue, or (c) presumed mycobacteriosis based on ophthalmic examination and positive interferon-gamma release assay. Twenty-five cats (31 eyes) were included; 14 cats (17/31 eyes, 55%) were blind at presentation (unilateral: = 12 cats; bilateral: = 2 cats); one unilaterally affected cat later became bilaterally blind. Read More

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http://journals.sagepub.com/doi/10.1177/0300985819844819
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http://dx.doi.org/10.1177/0300985819844819DOI Listing
September 2019
38 Reads

Vogt-Koyanagi-Harada Disease-Like Uveitis during Nivolumab (Anti-PD-1 Antibody) Treatment for Metastatic Cutaneous Malignant Melanoma.

Case Rep Ophthalmol 2019 Jan-Apr;10(1):67-74. Epub 2019 Feb 8.

Department of Ophthalmology, Shiga University of Medical Science, Otsu, Japan.

Nivolumab is an anti-programmed cell death protein 1 monoclonal antibody that is used to treat metastatic cutaneous malignant melanoma. Although bilateral uveitis has been reported as a side effect of nivolumab administration, there are few reports of Vogt-Koyanagi-Harada disease (VKH)-like uveitis. We report such a case. Read More

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http://dx.doi.org/10.1159/000496682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489058PMC
February 2019
8 Reads

Sympathetic Ophthalmia after Vitreoretinal Surgeries: Incidence, Clinical Presentations and Outcomes of a Rare Disease.

Semin Ophthalmol 2019 5;34(3):157-162. Epub 2019 May 5.

e Uveitis and Ocular Immunology Services , Tej Kohli Cornea Institute, L. V. Prasad Eye Institute , Hyderabad , India.

To evaluate clinical presentation, course and outcomes in patients without a history of penetrating ocular trauma who developed Sympathetic Ophthalmia (SO) following vitreoretinal surgeries Retrospective review of clinical records of all patients diagnosed and treated as S.O was done . All cases without a previous history of trauma were included and were analyzed with respect to clinical presentations, anatomic and visual outcomes. Read More

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http://dx.doi.org/10.1080/08820538.2019.1610464DOI Listing
July 2019
9 Reads
1.196 Impact Factor

Pattern and Outcome of Uveitis in a Tertiary Military Hospital in Thailand.

Ocul Immunol Inflamm 2020 Apr 22;28(3):424-432. Epub 2019 Apr 22.

Ocular inflammation and infection division, Department of Ophthalmology, Phramongkutklao hospital, Phramongkutklao college of Medicine, Bangkok, Thailand.

Background: Causes of uveitis vary upon the epidemiologic, racial, and geographical variations.

Objective: The objective of the study is to analyze pattern and outcome of uveitis in Phramongkutklao Hospital.

Methods: This is a retrospective study. Read More

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http://dx.doi.org/10.1080/09273948.2019.1589527DOI Listing
April 2020
8 Reads

Iridocorneal angle assessment using Swept-Source OCT in a patient with anterior granulomatous uveitis.

Arch Soc Esp Oftalmol 2019 Aug 17;94(8):e57-e58. Epub 2019 Apr 17.

Unidad de Gestión Clínica de Oftalmología, Hospital Universitario Virgen del Rocío, Sevilla, España.

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http://dx.doi.org/10.1016/j.oftal.2019.03.003DOI Listing
August 2019
4 Reads

Comparison of Clinical Features and Visual Outcome between Sympathetic Ophthalmia and Vogt-Koyanagi-Harada Disease in Chinese Patients.

Ophthalmology 2019 09 6;126(9):1297-1305. Epub 2019 Apr 6.

University Eye Clinic, Maastricht University, Maastricht, The Netherlands.

Purpose: To characterize the clinical features of sympathetic ophthalmia (SO) and compare SO and Vogt-Koyanagi-Harada (VKH) disease in Chinese patients.

Design: Retrospective case series.

Participants: A total of 131 consecutive SO and 500 VKH disease patients randomly selected from among those referred to our uveitis center from April 2008 through June 2018. Read More

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http://dx.doi.org/10.1016/j.ophtha.2019.03.049DOI Listing
September 2019
4 Reads

Treatment of presumed trematode-induced granulomatous anterior uveitis among children in rural areas of Egypt.

Eye (Lond) 2019 10 3;33(10):1525-1533. Epub 2019 Apr 3.

Mansoura Ophthalmic center, Mansoura University, Mansoura, Egypt.

Purpose: The purpose of this study is to evaluate the efficacy of systemic antiparasitic medications alone or in combination with surgical aspiration in management of presumed trematode-induced anterior uveitis in children.

Patients And Methods: Prospective case series. Children who presented with anterior chamber (AC) granuloma were included in the study. Read More

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http://dx.doi.org/10.1038/s41433-019-0428-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002623PMC
October 2019
33 Reads

Initial misdiagnosis of Vogt-Koyanagi-Harada disease.

Saudi J Ophthalmol 2019 Jan-Mar;33(1):52-55. Epub 2018 Dec 7.

The Eye Center and the Eye Foundation for Research in Ophthalmology, Riyadh, Saudi Arabia.

Purpose: To report the initial misdiagnosis of patients with Vogt-Koyanagi-Harada (VKH) disease.

Methods: The medical records of 76 consecutive patients diagnosed with VKH disease were reviewed retrospectively at The Eye Center, Riyadh, Saudi Arabia. Patients were referred to The Eye Center from Saudi Arabia and other Middle Eastern countries. Read More

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http://dx.doi.org/10.1016/j.sjopt.2018.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424695PMC
December 2018
6 Reads

Evaluation of changes in retinal and choroidal thickness using spectral domain optical coherence tomography in unilateral non granulomatous acute anterior uveitis.

J Fr Ophtalmol 2019 Feb 29;42(2):138-145. Epub 2018 Dec 29.

Clinique universitaire d'ophtalmologie, faculté de médecine, université d'Istanbul Medipol, Istanbul, Turkey.

Purpose: To assess retinal and choroidal thickness changes in eyes with a first episode of unilateral non granulomatous acute anterior uveitis (AU).

Methods: Thirty-one patients with acute unilateral non granulomatous AU who had undergone spectral domain optical coherence tomography (SD-OCT) of both eyes were included in this retrospective study. Retinal thickness (RT) as defined by the Early Treatment Diabetic Retinopathy Study (ETDRS) and subfoveal choroidal thickness (SFCT) obtained by SD-OCT were recorded. Read More

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http://dx.doi.org/10.1016/j.jfo.2018.04.018DOI Listing
February 2019
2 Reads

[Ocular sarcoidosis as a clinical manifestation of multiorgan involvement].

Vestn Oftalmol 2018;134(5):32-38

Saint Petersburg branch of S. Fyodorov Eye Microsurgery Federal State Institution, 21 Yaroslava Gasheka St., Saint Petersburg, Russian Federation, 192283.

Eye lesion in sarcoidosis is often the first and only sign of a disorder, which suggests a possible systemic disease. Currently sarcoidosis is considered a multisystemic granulomatous disease that requires multidisciplinary approach.

Purpose: To study the prevalence and clinical aspects of sarcoidosis eyes based on the representative sample of patients diagnosed with extraocular nonspecific granulomatous disease. Read More

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http://dx.doi.org/10.17116/oftalma201813405132DOI Listing
August 2019
29 Reads

Sympathetic Ophthalmia: Experience from a Tertiary Care Center in Northern India.

J Ophthalmic Vis Res 2018 Oct-Dec;13(4):439-446

Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Purpose: To describe our clinical experience with sympathetic ophthalmia (SO) at a tertiary eye care center in north India.

Methods: In this retrospective case series, analysis of the clinical features and visual outcomes of patients diagnosed with SO between March 2012 and March 2016 were performed.

Results: Ten male and four female patients (median age, 15. Read More

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http://dx.doi.org/10.4103/jovr.jovr_86_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210884PMC
November 2018
6 Reads

[Effect of 2% ganciclovir eye drops on cytomegalovirus positive Posner-Schlossman syndrome].

Zhonghua Yan Ke Za Zhi 2018 Nov;54(11):833-838

Department of Ophthalmology, Eye & ENT Hospital of Fudan University, NHC Key Laboratory of Myopia(Fudan University); Laboratory of Myopia, Chinese Academy of Medical Science, Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai 200031, China.

To observe the effect of 2% ganciclovir eye drops on Posner-Schlossman syndrome (PSS) patients with positive cytomegalovirus (CMV) in aqueous humor. Prospective study. The cases clinically diagnosed as PSS with positive CMV were enrolled from August 2017 to January 2018 at Department of Ophthalmology, Eye & ENT Hospital of Fudan University. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0412-4081.2018.11.007DOI Listing
November 2018
22 Reads

Aqueous tap and rapid diagnosis of cytomegalovirus anterior uveitis: the Reggio Emilia experience.

Graefes Arch Clin Exp Ophthalmol 2019 Jan 3;257(1):181-186. Epub 2018 Nov 3.

Ocular Immunology Unit, Azienda USL IRCCS, Reggio Emilia, Italy.

Purpose: The diagnosis of cytomegalovirus (CMV) anterior uveitis in immunocompetent patients requires confirmation by polymerase chain reaction (PCR) analysis and/or intraocular antibody index (AI) assay. In this study, we analyzed the different contributions of PCR and AI to CMV diagnosis by performing one single aqueous tap.

Methods: A retrospective chart review was conducted of HIV-negative patients attending the Ocular Immunology Unit of Azienda Unità Sanitaria Locale - IRCCS, Reggio Emilia, Italy, from March 2015 to April 2018 with a diagnosis of hypertensive anterior granulomatous uveitis compatible with suspected CMV etiology. Read More

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http://link.springer.com/10.1007/s00417-018-4180-9
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http://dx.doi.org/10.1007/s00417-018-4180-9DOI Listing
January 2019
19 Reads

Demystifying viral anterior uveitis: A review.

Clin Exp Ophthalmol 2019 04 13;47(3):320-333. Epub 2018 Nov 13.

Singapore National Eye Centre, Singapore, Singapore.

A viral aetiology should be suspected when anterior uveitis is accompanied by ocular hypertension, diffuse stellate keratic precipitates or the presence of iris atrophy. The most common viruses associated with anterior uveitis include herpes simplex virus, varicella-zoster virus, cytomegalovirus and rubella virus. They may present as the following: Firstly, granulomatous cluster of small and medium-sized keratic precipitates in Arlt's triangle, with or without corneal scars, suggestive of herpes simplex or varicella-zoster virus infection. Read More

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http://doi.wiley.com/10.1111/ceo.13417
Publisher Site
http://dx.doi.org/10.1111/ceo.13417DOI Listing
April 2019
51 Reads

TINU-associated Fanconi syndrome: a case report and review of literature.

BMC Nephrol 2018 10 19;19(1):274. Epub 2018 Oct 19.

Department of internal medicine and infectious diseases, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, 10 Av. Hippocrate, 1200, Brussels, Belgium.

Background: Tubulo-interstitial Nephritis and Uveitis (TINU) syndrome is a rare oculo-renal inflammatory disease. Renal tubular defects are usually found, but full proximal tubular abnormalities have rarely been described.

Case Presentation: We report the case of a 55-year old woman, native from Morocco, presenting with bilateral, non-granulomatous, anterior uveitis, mild renal insufficiency, leucocyturia and glycosuria. Read More

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http://dx.doi.org/10.1186/s12882-018-1077-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194638PMC
October 2018
5 Reads

Clinical Characteristics and Treatment of 308 Panuveitis Patients over 10 Years: Results from the KKESH Uveitis Survey Study Group.

Ocul Immunol Inflamm 2019 10;27(8):1296-1304. Epub 2018 Oct 10.

Vitreoretinal and Uveitis Division, King Khaled Eye Specialist Hospital, Riyadh, Kingdom of Saudi Arabia.

: To describe the clinical characteristics and surgical outcomes of panuveitis over a 10-year period.: Data were collected on panuveitis etiology, treatment, surgery and change in vision.: Overall, 308 patients (594 eyes) were evaluated, 54. Read More

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https://www.tandfonline.com/doi/full/10.1080/09273948.2018.1
Publisher Site
http://dx.doi.org/10.1080/09273948.2018.1523436DOI Listing
May 2020
19 Reads

Optic Neuropathy and Macular Ischemia Associated with Neurosarcoidosis: A Case Report.

Turk J Ophthalmol 2018 Aug 4;48(4):202-205. Epub 2018 Sep 4.

University of Health Sciences, Kartal Dr. Lütfi Kırdar Training and Research Hospital, Ophthalmology Clinic, İstanbul, Turkey.

In this study, we present a case of bilateral optic neuropathy and macular ischemia in the right eye associated with neurosarcoidosis. A 26-year-old woman presented to our clinic with complaints of bilateral blurred vision. Bilateral granulomatous anterior uveitis, vitritis, optic neuropathy, and macular ischemia were detected in the right eye in slit-lamp examination. Read More

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http://dx.doi.org/10.4274/tjo.49799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126102PMC
August 2018
37 Reads

Granulomatous Uveitis and Conjunctivitis Due to Common Variable Immune Deficiency: A Case Report.

Ocul Immunol Inflamm 2019 24;27(7):1124-1126. Epub 2018 Aug 24.

Gavin Herbert Eye Institute , Irvine , California , USA.

: To describe a case of granulomatous anterior uveitis and histologically confirmed chronic granulomatous conjunctivitis in the presence of common variable immune deficiency (CVID). : Interventional case report. : A 72-year-old female with a history of CVID treated with regular intravenous immunoglobulin (IVIG) infusions developed chronic conjunctivitis and granulomatous anterior uveitis. Read More

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https://www.tandfonline.com/doi/full/10.1080/09273948.2018.1
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http://dx.doi.org/10.1080/09273948.2018.1497666DOI Listing
April 2020
7 Reads

Patterns of uveitis in patients with proven systemic (pulmonary and extrapulmonary) tuberculosis.

Int Ophthalmol 2019 Aug 18;39(8):1665-1667. Epub 2018 Jul 18.

Retina and Uvea Services, Dr R P Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.

Purpose: To report patterns of uveitis in patients with systemic tuberculosis.

Methods: Records of patients presenting at uvea clinic of a tertiary eye care centre were evaluated retrospectively, and 47 cases with proven systemic tuberculosis were analyzed for patterns of uveitis. Tuberculosis had been proven with a combination of radio imaging and detection of acid fast bacilli in body fluids. Read More

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http://dx.doi.org/10.1007/s10792-018-0989-9DOI Listing
August 2019
52 Reads

Uveitis and internuclear ophthalmoplegia as ocular manifestations of sarcoidosis.

Saudi J Ophthalmol 2018 Apr-Jun;32(2):167-170. Epub 2018 Jan 4.

Department of Surgery, Ophthalmology Unit, Augusto Murri Hospital, ASUR 4, Fermo, Italy.

Sarcoidosis is a multisystemic granulomatous chronic disease of unknown etiology with a wide range of clinical presentations. Diagnosis of sarcoidosis in patients with ocular manifestations can be challenging. We first describe a case of sarcoidosis presented with pulmonary involvement and both uveitis and internuclear ophthalmoplegia as ocular manifestations. Read More

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http://dx.doi.org/10.1016/j.sjopt.2017.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010614PMC
January 2018
6 Reads

Hypertensive acute granulomatous anterior uveitis as a side effect of topical brimonidine.

Arch Soc Esp Oftalmol 2018 Oct 15;93(10):511-514. Epub 2018 Jun 15.

Departamento de Oftalmología, Hospital Clínico Universitario, Valencia, España; Facultad de Medicina, Universidad de Valencia, Valencia, España.

Clinical Case: The case concerns an 81-year-old woman on treatment with a topical fixed combination of timolol and brimonidine who was diagnosed in the Emergency Department with acute anterior granulomatous hypertensive uveitis. The patient responded favourably to the withdrawal of the eye drops without showing any subsequent relapse.

Discussion: Uveitis due to brimonidine is a rare adverse effect, but it must be known. Read More

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http://dx.doi.org/10.1016/j.oftal.2018.05.005DOI Listing
October 2018
5 Reads

Differential Diagnosis of Viral-Induced Anterior Uveitis.

Ocul Immunol Inflamm 2018 5;26(5):726-731. Epub 2018 Jun 5.

a Department of Ophthalmology, CHU St-Pierre and Brugmann , Université Libre de Bruxelles , Bruxelles , Belgium.

Diagnosis of uveitis is often challenging, but can be easy in typical viral-induced anterior uveitis (VIAU). Associated symptoms and signs are an important source of information. Certain classical clinical features such as keratic precipitates (KPs) distribution, iris atrophy, elevated intraocular pressure (IOP), and unilaterality are commonly used to support the diagnosis of VIAU. Read More

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https://www.tandfonline.com/doi/full/10.1080/09273948.2018.1
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http://dx.doi.org/10.1080/09273948.2018.1468470DOI Listing
September 2018
31 Reads

Patterns of Uveitis at a Tertiary Referral Center in Northeastern Iran.

J Ophthalmic Vis Res 2018 Apr-Jun;13(2):138-143

Eye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Purpose: To describe the demographic and clinical patterns of patients with uveitis referred to a tertiary center in northeastern Iran.

Methods: This cross-sectional retrospective study included 235 patients with uveitis who had been referred to the uveitis clinic of Khatam-Al-Anbia eye hospital, affiliated to Mashhad University of Medical Sciences, from February 2013 to March 2014. Data regarding patient age, sex, anatomical location of the disease, and etiologic and clinical features were analyzed. Read More

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http://dx.doi.org/10.4103/jovr.jovr_67_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905306PMC
May 2018
27 Reads

Topical Corticosteroid-Resolved Rubeosis Iridis with Neovascular Glaucoma Caused by Noninfectious Granulomatous Uveitis.

Case Rep Ophthalmol 2018 Jan-Apr;9(1):243-247. Epub 2018 Mar 28.

Department of Ophthalmology, National Defense Medical College, Tokorozawa, Japan.

Purpose: We report a case of topical corticosteroid treatment-resolved rubeosis iridis with neovascular glaucoma (NVG) caused by noninfectious granulomatous uveitis.

Case Report: A 61-year-old woman with left ocular pain and blurred vision was referred to our department. Visual acuity and intraocular pressure (IOP) were 20/60 and 37 mm Hg in the left eye, respectively. Read More

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http://dx.doi.org/10.1159/000488137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903156PMC
March 2018
6 Reads

S100A12 and S100A8/9 proteins are biomarkers of articular disease activity in Blau syndrome.

Rheumatology (Oxford) 2018 Jul;57(7):1299-1304

KU Leuven, Department of Microbiology and Immunology, Pediatric Immunology, University Hospitals Leuven, Pediatric Rheumatology, Leuven, Belgium.

Objective: To identify biomarkers of articular and ocular disease activity in patients with Blau syndrome (BS).

Methods: Multiplex plasma protein arrays were performed in five BS patients and eight normal healthy volunteers (NHVs). Plasma S100A12 and S100A8/9 were subsequently measured by ELISA at baseline and 1-year follow-up in all patients from a prospective multicentre cohort study. Read More

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http://dx.doi.org/10.1093/rheumatology/key090DOI Listing
July 2018
34 Reads
4.470 Impact Factor

[Ocular manifestations in Behçet's disease].

Rev Med Interne 2018 Sep 4;39(9):738-745. Epub 2018 Apr 4.

Sorbonne universités, UPMC université Paris 06, UMR 7211, et DHU i2B-inflammation-immunopathologie-biothérapie, 75005 Paris, France; Inserm, UMR_S 959, 75013 Paris, France; CNRS, FRE3632, 75005 Paris, France; Département de médecine interne et d'immunologie clinique, université Pierre-et-Marie-Curie, groupe hospitalier Pitié-Salpêtrière, AP-HP, 75013 Paris, France; Centre national de référence des maladies auto-immunes systémiques rares, centre national de référence des maladies auto-inflammatoires et de l'amylose, France. Electronic address:

Ocular disease in Behçet's disease is frequent and may be associated with a poor functional prognosis. Uveitis is the most common ocular manifestation in Behçet's disease and represents a diagnostic criterion of the disease. The ocular involvement is inaugural of the disease in 20% of the cases or may develop 2 to 3 years after the beginning of the extraocular signs. Read More

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http://dx.doi.org/10.1016/j.revmed.2018.02.022DOI Listing
September 2018
13 Reads

Use of recombinant tissue plasminogen activator for treatment of recalcitrant anterior uveitis: A case series.

J Taibah Univ Med Sci 2018 Oct 6;13(5):483-487. Epub 2018 Apr 6.

Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia Health Campus, Kota Bharu, Malaysia.

Management of inflammation after surgery for recalcitrant anterior uveitis is challenging. Herein, we report successful treatment using intracameral injection of recombinant tissue plasminogen activator (rtPA) in two patients with recalcitrant anterior uveitis, due to infective uveitis and Vogt-Koyanagi-Harada disease, respectively. A 40-year-old woman presented with bilateral redness and vision reduction that had persisted 2 weeks. Read More

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http://dx.doi.org/10.1016/j.jtumed.2018.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694932PMC
October 2018
1 Read

Uveitis and serous retinal detachment secondary to systemic dabrafenib and trametinib.

Arch Soc Esp Oftalmol 2018 Sep 23;93(9):458-462. Epub 2018 Mar 23.

Servicio de Oftalmología, Hospital Universitario Virgen del Rocío, Sevilla, España.

Case Report: The case is presented of a 39-year-old woman with metastatic melanoma treated with dabrafenib and trametinib. She presented with a severe acute panuveitis with granulomatous anterior uveitis, vitritis, and multiple serous retinal detachments. Dabrafenib and trametinib were suspended, and treatment with a systemic and topical corticosteroid was started. Read More

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http://dx.doi.org/10.1016/j.oftal.2018.01.008DOI Listing
September 2018
4 Reads

Role of CT Chest and Cytology in Differentiating Tuberculosis from Presumed Sarcoidosis in Uveitis.

Ocul Immunol Inflamm 2019 8;27(7):1041-1048. Epub 2018 Feb 8.

Departments of Pulmonary Medicine, Post Graduate Institute of Medical Education and Research , Chandigarh , India.

: To report the role of CT chest and cytology in suspected tubercular and sarcoid uveitis. : This is a retrospective, interventional case series of 376 uveitis patients with suspected ocular tuberculosis (TB)/sarcoidosis seen between January 2010 and April 2015 at the Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh. All underwent CT chest, and had following inclusion criteria: (1) Presence of active granulomatous anterior/intermediate/posterior uveitis or panuveitis; (2) a documented tuberculin skin test/QuantiFERON-TB Gold test; (3) all other causes of infectious/non-infectious uveitis ruled out. Read More

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https://www.tandfonline.com/doi/full/10.1080/09273948.2018.1
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http://dx.doi.org/10.1080/09273948.2018.1425460DOI Listing
April 2020
16 Reads