402 results match your criteria Uveitis Anterior Granulomatous


Pattern and Outcome of Uveitis in a Tertiary Military Hospital in Thailand.

Ocul Immunol Inflamm 2019 Apr 22:1-9. Epub 2019 Apr 22.

a Ocular inflammation and infection division, Department of Ophthalmology, Phramongkutklao hospital , Phramongkutklao college of Medicine , Bangkok , Thailand.

Background: Causes of uveitis vary upon the epidemiologic, racial, and geographical variations.

Objective: The objective of the study is to analyze pattern and outcome of uveitis in Phramongkutklao Hospital.

Methods: This is a retrospective study. Read More

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http://dx.doi.org/10.1080/09273948.2019.1589527DOI Listing

Iridocorneal angle assessment using Swept-Source OCT in a patient with anterior granulomatous uveitis.

Arch Soc Esp Oftalmol 2019 Apr 17. Epub 2019 Apr 17.

Unidad de Gestión Clínica de Oftalmología, Hospital Universitario Virgen del Rocío, Sevilla, España.

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http://dx.doi.org/10.1016/j.oftal.2019.03.003DOI Listing

Comparison of clinical features and visual outcome between Sympathetic ophthalmia and Vogt-Koyanagi-Harada disease in Chinese Patients.

Ophthalmology 2019 Apr 5. Epub 2019 Apr 5.

Purpose: To characterize the clinical features of Sympathetic ophthalmia (SO) and make a comparison between SO and Vogt-Koyanagi-Harada (VKH) disease in Chinese patients.

Design: Retrospective case series.

Participants: A total of 131 consecutive SO and 500 VKH patients randomly selected out of those referred to our uveitis center from April 2008 to June 2018. Read More

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http://dx.doi.org/10.1016/j.ophtha.2019.03.049DOI Listing

Treatment of presumed trematode-induced granulomatous anterior uveitis among children in rural areas of Egypt.

Eye (Lond) 2019 Apr 3. Epub 2019 Apr 3.

Mansoura Ophthalmic center, Mansoura University, Mansoura, Egypt.

Purpose: The purpose of this study is to evaluate the efficacy of systemic antiparasitic medications alone or in combination with surgical aspiration in management of presumed trematode-induced anterior uveitis in children.

Patients And Methods: Prospective case series. Children who presented with anterior chamber (AC) granuloma were included in the study. Read More

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http://dx.doi.org/10.1038/s41433-019-0428-9DOI Listing
April 2019
5 Reads

Initial misdiagnosis of Vogt-Koyanagi-Harada disease.

Saudi J Ophthalmol 2019 Jan-Mar;33(1):52-55. Epub 2018 Dec 7.

The Eye Center and the Eye Foundation for Research in Ophthalmology, Riyadh, Saudi Arabia.

Purpose: To report the initial misdiagnosis of patients with Vogt-Koyanagi-Harada (VKH) disease.

Methods: The medical records of 76 consecutive patients diagnosed with VKH disease were reviewed retrospectively at The Eye Center, Riyadh, Saudi Arabia. Patients were referred to The Eye Center from Saudi Arabia and other Middle Eastern countries. Read More

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http://dx.doi.org/10.1016/j.sjopt.2018.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424695PMC
December 2018
2 Reads

Evaluation of changes in retinal and choroidal thickness using spectral domain optical coherence tomography in unilateral non granulomatous acute anterior uveitis.

J Fr Ophtalmol 2019 Feb 29;42(2):138-145. Epub 2018 Dec 29.

Clinique universitaire d'ophtalmologie, faculté de médecine, université d'Istanbul Medipol, Istanbul, Turkey.

Purpose: To assess retinal and choroidal thickness changes in eyes with a first episode of unilateral non granulomatous acute anterior uveitis (AU).

Methods: Thirty-one patients with acute unilateral non granulomatous AU who had undergone spectral domain optical coherence tomography (SD-OCT) of both eyes were included in this retrospective study. Retinal thickness (RT) as defined by the Early Treatment Diabetic Retinopathy Study (ETDRS) and subfoveal choroidal thickness (SFCT) obtained by SD-OCT were recorded. Read More

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http://dx.doi.org/10.1016/j.jfo.2018.04.018DOI Listing
February 2019

[Ocular sarcoidosis as a clinical manifestation of multiorgan involvement].

Vestn Oftalmol 2018;134(5):32-38

Saint Petersburg branch of S. Fyodorov Eye Microsurgery Federal State Institution, 21 Yaroslava Gasheka St., Saint Petersburg, Russian Federation, 192283.

Eye lesion in sarcoidosis is often the first and only sign of a disorder, which suggests a possible systemic disease. Currently sarcoidosis is considered a multisystemic granulomatous disease that requires multidisciplinary approach.

Purpose: To study the prevalence and clinical aspects of sarcoidosis eyes based on the representative sample of patients diagnosed with extraocular nonspecific granulomatous disease. Read More

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http://dx.doi.org/10.17116/oftalma201813405132DOI Listing
January 2018
14 Reads

Sympathetic Ophthalmia: Experience from a Tertiary Care Center in Northern India.

J Ophthalmic Vis Res 2018 Oct-Dec;13(4):439-446

Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Purpose: To describe our clinical experience with sympathetic ophthalmia (SO) at a tertiary eye care center in north India.

Methods: In this retrospective case series, analysis of the clinical features and visual outcomes of patients diagnosed with SO between March 2012 and March 2016 were performed.

Results: Ten male and four female patients (median age, 15. Read More

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http://dx.doi.org/10.4103/jovr.jovr_86_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210884PMC
November 2018
1 Read

[Effect of 2% ganciclovir eye drops on cytomegalovirus positive Posner-Schlossman syndrome].

Zhonghua Yan Ke Za Zhi 2018 Nov;54(11):833-838

Department of Ophthalmology, Eye & ENT Hospital of Fudan University, NHC Key Laboratory of Myopia(Fudan University); Laboratory of Myopia, Chinese Academy of Medical Science, Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai 200031, China.

To observe the effect of 2% ganciclovir eye drops on Posner-Schlossman syndrome (PSS) patients with positive cytomegalovirus (CMV) in aqueous humor. Prospective study. The cases clinically diagnosed as PSS with positive CMV were enrolled from August 2017 to January 2018 at Department of Ophthalmology, Eye & ENT Hospital of Fudan University. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0412-4081.2018.11.007DOI Listing
November 2018
18 Reads

Aqueous tap and rapid diagnosis of cytomegalovirus anterior uveitis: the Reggio Emilia experience.

Graefes Arch Clin Exp Ophthalmol 2019 Jan 3;257(1):181-186. Epub 2018 Nov 3.

Ocular Immunology Unit, Azienda USL IRCCS, Reggio Emilia, Italy.

Purpose: The diagnosis of cytomegalovirus (CMV) anterior uveitis in immunocompetent patients requires confirmation by polymerase chain reaction (PCR) analysis and/or intraocular antibody index (AI) assay. In this study, we analyzed the different contributions of PCR and AI to CMV diagnosis by performing one single aqueous tap.

Methods: A retrospective chart review was conducted of HIV-negative patients attending the Ocular Immunology Unit of Azienda Unità Sanitaria Locale - IRCCS, Reggio Emilia, Italy, from March 2015 to April 2018 with a diagnosis of hypertensive anterior granulomatous uveitis compatible with suspected CMV etiology. Read More

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http://link.springer.com/10.1007/s00417-018-4180-9
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http://dx.doi.org/10.1007/s00417-018-4180-9DOI Listing
January 2019
9 Reads

Demystifying viral anterior uveitis: a review.

Clin Exp Ophthalmol 2018 Oct 21. Epub 2018 Oct 21.

Singapore National Eye Centre, Singapore, Singapore.

A viral aetiology should be suspected when anterior uveitis is accompanied by ocular hypertension, diffuse stellate keratic precipitates or the presence of iris atrophy. The most common viruses associated with anterior uveitis include herpes simplex virus, varicella-zoster virus, cytomegalovirus and rubella virus. They may present as the following: Firstly, granulomatous cluster of small and medium-sized keratic precipitates in Arlt's triangle, with or without corneal scars, suggestive of herpes simplex or varicella-zoster virus infection. Read More

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http://doi.wiley.com/10.1111/ceo.13417
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http://dx.doi.org/10.1111/ceo.13417DOI Listing
October 2018
24 Reads

TINU-associated Fanconi syndrome: a case report and review of literature.

BMC Nephrol 2018 Oct 19;19(1):274. Epub 2018 Oct 19.

Department of internal medicine and infectious diseases, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, 10 Av. Hippocrate, 1200, Brussels, Belgium.

Background: Tubulo-interstitial Nephritis and Uveitis (TINU) syndrome is a rare oculo-renal inflammatory disease. Renal tubular defects are usually found, but full proximal tubular abnormalities have rarely been described.

Case Presentation: We report the case of a 55-year old woman, native from Morocco, presenting with bilateral, non-granulomatous, anterior uveitis, mild renal insufficiency, leucocyturia and glycosuria. Read More

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http://dx.doi.org/10.1186/s12882-018-1077-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194638PMC
October 2018
2 Reads

Clinical Characteristics and Treatment of 308 Panuveitis Patients over 10 Years: Results from the KKESH Uveitis Survey Study Group.

Ocul Immunol Inflamm 2018 Oct 10:1-9. Epub 2018 Oct 10.

b Vitreoretinal and Uveitis Division , King Khaled Eye Specialist Hospital , Riyadh , Kingdom of Saudi Arabia.

Purpose: To describe the clinical characteristics and surgical outcomes of panuveitis over a 10-year period.

Methods: Data were collected on panuveitis etiology, treatment, surgery and change in vision.

Results: Overall, 308 patients (594 eyes) were evaluated, 54. Read More

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https://www.tandfonline.com/doi/full/10.1080/09273948.2018.1
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http://dx.doi.org/10.1080/09273948.2018.1523436DOI Listing
October 2018
5 Reads

Optic Neuropathy and Macular Ischemia Associated with Neurosarcoidosis: A Case Report.

Turk J Ophthalmol 2018 Aug 4;48(4):202-205. Epub 2018 Sep 4.

University of Health Sciences, Kartal Dr. Lütfi Kırdar Training and Research Hospital, Ophthalmology Clinic, İstanbul, Turkey.

In this study, we present a case of bilateral optic neuropathy and macular ischemia in the right eye associated with neurosarcoidosis. A 26-year-old woman presented to our clinic with complaints of bilateral blurred vision. Bilateral granulomatous anterior uveitis, vitritis, optic neuropathy, and macular ischemia were detected in the right eye in slit-lamp examination. Read More

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http://dx.doi.org/10.4274/tjo.49799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126102PMC
August 2018
22 Reads

Granulomatous Uveitis and Conjunctivitis Due to Common Variable Immune Deficiency: A Case Report.

Ocul Immunol Inflamm 2018 Aug 24:1-3. Epub 2018 Aug 24.

b Gavin Herbert Eye Institute , Irvine , California , USA.

Purpose: To describe a case of granulomatous anterior uveitis and histologically confirmed chronic granulomatous conjunctivitis in the presence of common variable immune deficiency (CVID).

Methods: Interventional case report.

Results: A 72-year-old female with a history of CVID treated with regular intravenous immunoglobulin (IVIG) infusions developed chronic conjunctivitis and granulomatous anterior uveitis. Read More

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https://www.tandfonline.com/doi/full/10.1080/09273948.2018.1
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http://dx.doi.org/10.1080/09273948.2018.1497666DOI Listing
August 2018
4 Reads

Patterns of uveitis in patients with proven systemic (pulmonary and extrapulmonary) tuberculosis.

Int Ophthalmol 2018 Jul 18. Epub 2018 Jul 18.

Retina and Uvea Services, Dr R P Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.

Purpose: To report patterns of uveitis in patients with systemic tuberculosis.

Methods: Records of patients presenting at uvea clinic of a tertiary eye care centre were evaluated retrospectively, and 47 cases with proven systemic tuberculosis were analyzed for patterns of uveitis. Tuberculosis had been proven with a combination of radio imaging and detection of acid fast bacilli in body fluids. Read More

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http://dx.doi.org/10.1007/s10792-018-0989-9DOI Listing
July 2018
26 Reads

Uveitis and internuclear ophthalmoplegia as ocular manifestations of sarcoidosis.

Saudi J Ophthalmol 2018 Apr-Jun;32(2):167-170. Epub 2018 Jan 4.

Department of Surgery, Ophthalmology Unit, Augusto Murri Hospital, ASUR 4, Fermo, Italy.

Sarcoidosis is a multisystemic granulomatous chronic disease of unknown etiology with a wide range of clinical presentations. Diagnosis of sarcoidosis in patients with ocular manifestations can be challenging. We first describe a case of sarcoidosis presented with pulmonary involvement and both uveitis and internuclear ophthalmoplegia as ocular manifestations. Read More

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http://dx.doi.org/10.1016/j.sjopt.2017.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010614PMC
January 2018
1 Read

Hypertensive acute granulomatous anterior uveitis as a side effect of topical brimonidine.

Arch Soc Esp Oftalmol 2018 Oct 15;93(10):511-514. Epub 2018 Jun 15.

Departamento de Oftalmología, Hospital Clínico Universitario, Valencia, España; Facultad de Medicina, Universidad de Valencia, Valencia, España.

Clinical Case: The case concerns an 81-year-old woman on treatment with a topical fixed combination of timolol and brimonidine who was diagnosed in the Emergency Department with acute anterior granulomatous hypertensive uveitis. The patient responded favourably to the withdrawal of the eye drops without showing any subsequent relapse.

Discussion: Uveitis due to brimonidine is a rare adverse effect, but it must be known. Read More

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http://dx.doi.org/10.1016/j.oftal.2018.05.005DOI Listing
October 2018
2 Reads

Differential Diagnosis of Viral-Induced Anterior Uveitis.

Ocul Immunol Inflamm 2018 5;26(5):726-731. Epub 2018 Jun 5.

a Department of Ophthalmology, CHU St-Pierre and Brugmann , Université Libre de Bruxelles , Bruxelles , Belgium.

Diagnosis of uveitis is often challenging, but can be easy in typical viral-induced anterior uveitis (VIAU). Associated symptoms and signs are an important source of information. Certain classical clinical features such as keratic precipitates (KPs) distribution, iris atrophy, elevated intraocular pressure (IOP), and unilaterality are commonly used to support the diagnosis of VIAU. Read More

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https://www.tandfonline.com/doi/full/10.1080/09273948.2018.1
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http://dx.doi.org/10.1080/09273948.2018.1468470DOI Listing
September 2018
22 Reads

Patterns of Uveitis at a Tertiary Referral Center in Northeastern Iran.

J Ophthalmic Vis Res 2018 Apr-Jun;13(2):138-143

Eye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Purpose: To describe the demographic and clinical patterns of patients with uveitis referred to a tertiary center in northeastern Iran.

Methods: This cross-sectional retrospective study included 235 patients with uveitis who had been referred to the uveitis clinic of Khatam-Al-Anbia eye hospital, affiliated to Mashhad University of Medical Sciences, from February 2013 to March 2014. Data regarding patient age, sex, anatomical location of the disease, and etiologic and clinical features were analyzed. Read More

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http://dx.doi.org/10.4103/jovr.jovr_67_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905306PMC
May 2018
6 Reads

Topical Corticosteroid-Resolved Rubeosis Iridis with Neovascular Glaucoma Caused by Noninfectious Granulomatous Uveitis.

Case Rep Ophthalmol 2018 Jan-Apr;9(1):243-247. Epub 2018 Mar 28.

Department of Ophthalmology, National Defense Medical College, Tokorozawa, Japan.

Purpose: We report a case of topical corticosteroid treatment-resolved rubeosis iridis with neovascular glaucoma (NVG) caused by noninfectious granulomatous uveitis.

Case Report: A 61-year-old woman with left ocular pain and blurred vision was referred to our department. Visual acuity and intraocular pressure (IOP) were 20/60 and 37 mm Hg in the left eye, respectively. Read More

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http://dx.doi.org/10.1159/000488137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903156PMC
March 2018
2 Reads

S100A12 and S100A8/9 proteins are biomarkers of articular disease activity in Blau syndrome.

Rheumatology (Oxford) 2018 Apr 7. Epub 2018 Apr 7.

KU Leuven, Department of Microbiology and Immunology, Pediatric Immunology, University Hospitals Leuven, Pediatric Rheumatology, Leuven, Belgium.

Objective: To identify biomarkers of articular and ocular disease activity in patients with Blau syndrome (BS).

Methods: Multiplex plasma protein arrays were performed in five BS patients and eight normal healthy volunteers (NHVs). Plasma S100A12 and S100A8/9 were subsequently measured by ELISA at baseline and 1-year follow-up in all patients from a prospective multicentre cohort study. Read More

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http://dx.doi.org/10.1093/rheumatology/key090DOI Listing
April 2018
12 Reads
4.470 Impact Factor

[Ocular manifestations in Behçet's disease].

Rev Med Interne 2018 Sep 4;39(9):738-745. Epub 2018 Apr 4.

Sorbonne universités, UPMC université Paris 06, UMR 7211, et DHU i2B-inflammation-immunopathologie-biothérapie, 75005 Paris, France; Inserm, UMR_S 959, 75013 Paris, France; CNRS, FRE3632, 75005 Paris, France; Département de médecine interne et d'immunologie clinique, université Pierre-et-Marie-Curie, groupe hospitalier Pitié-Salpêtrière, AP-HP, 75013 Paris, France; Centre national de référence des maladies auto-immunes systémiques rares, centre national de référence des maladies auto-inflammatoires et de l'amylose, France. Electronic address:

Ocular disease in Behçet's disease is frequent and may be associated with a poor functional prognosis. Uveitis is the most common ocular manifestation in Behçet's disease and represents a diagnostic criterion of the disease. The ocular involvement is inaugural of the disease in 20% of the cases or may develop 2 to 3 years after the beginning of the extraocular signs. Read More

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http://dx.doi.org/10.1016/j.revmed.2018.02.022DOI Listing
September 2018
7 Reads

Uveitis and serous retinal detachment secondary to systemic dabrafenib and trametinib.

Arch Soc Esp Oftalmol 2018 Sep 23;93(9):458-462. Epub 2018 Mar 23.

Servicio de Oftalmología, Hospital Universitario Virgen del Rocío, Sevilla, España.

Case Report: The case is presented of a 39-year-old woman with metastatic melanoma treated with dabrafenib and trametinib. She presented with a severe acute panuveitis with granulomatous anterior uveitis, vitritis, and multiple serous retinal detachments. Dabrafenib and trametinib were suspended, and treatment with a systemic and topical corticosteroid was started. Read More

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http://dx.doi.org/10.1016/j.oftal.2018.01.008DOI Listing
September 2018
1 Read

Role of CT Chest and Cytology in Differentiating Tuberculosis from Presumed Sarcoidosis in Uveitis.

Ocul Immunol Inflamm 2018 Feb 8:1-8. Epub 2018 Feb 8.

b Departments of Pulmonary Medicine , Post Graduate Institute of Medical Education and Research , Chandigarh , India.

Purpose: To report the role of CT chest and cytology in suspected tubercular and sarcoid uveitis.

Methods: This is a retrospective, interventional case series of 376 uveitis patients with suspected ocular tuberculosis (TB)/sarcoidosis seen between January 2010 and April 2015 at the Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh. All underwent CT chest, and had following inclusion criteria: (1) Presence of active granulomatous anterior/intermediate/posterior uveitis or panuveitis; (2) a documented tuberculin skin test/QuantiFERON-TB Gold test; (3) all other causes of infectious/non-infectious uveitis ruled out. Read More

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https://www.tandfonline.com/doi/full/10.1080/09273948.2018.1
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http://dx.doi.org/10.1080/09273948.2018.1425460DOI Listing
February 2018
7 Reads

[Anterior uveitis].

Authors:
J Gueudry M Muraine

J Fr Ophtalmol 2018 Feb 1;41(2):170-182. Epub 2018 Feb 1.

Service d'ophtalmologie, hôpital Charles-Nicolle, CHU de Rouen, 1, rue de Germont, 76031 Rouen Cedex, France.

Anterior uveitis is the most common form of uveitis. There are several known and many possible etiologies for anterior uveitis. After examining the posterior segment and ruling out masquerade syndromes, the main step of etiologic diagnosis is clinical characterization. Read More

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http://dx.doi.org/10.1016/j.jfo.2017.06.012DOI Listing
February 2018
1 Read

Anterior uveitis.

Authors:
J Gueudry M Muraine

J Fr Ophtalmol 2018 Jan 29;41(1):e11-e21. Epub 2017 Dec 29.

Service d'ophtalmologie, hôpital Charles-Nicolle, CHU de Rouen, 1, rue de Germont, 76031 Rouen cedex, France.

Anterior Uveitis is the most common form of uveitis. There are several known and many possible etiologies for anterior uveitis. After examining the posterior segment and ruling out masquerade syndromes, the main step of etiologic diagnosis is clinical characterization. Read More

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http://dx.doi.org/10.1016/j.jfo.2017.11.003DOI Listing
January 2018
2 Reads

Corticotherapy vs. Corticotherapy Plus Immunosuppressive Therapy in Acute Vogt-Koyanagi-Harada Disease.

Arch Soc Esp Oftalmol 2018 May 16;93(5):225-230. Epub 2017 Dec 16.

Asociación Para Evitar la Ceguera en México, Hospital Luis Sánchez Bulnes, Ciudad de México, México.

Introduction: Vogt-Koyanagi-Harada disease is a multisystem disorder characterized by a bilateral granulomatous panuveitis. Multiple therapeutic regimens have been used to control inflammation in acute uveitic stage to prevent irreversible visual loss. The purpose of this paper is to compare the effect, on functional and anatomic outcomes, of early treatment with standard corticotherapy vs. Read More

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http://dx.doi.org/10.1016/j.oftal.2017.09.010DOI Listing
May 2018
6 Reads

Bilateral uveitis and macular edema induced by Nivolumab: a case report.

BMC Ophthalmol 2017 Dec 1;17(1):227. Epub 2017 Dec 1.

Department of Dermatology, Service de dermatologie, ImmuCare, Centre Hospitalier Lyon-Sud, Hospices Civils de Lyon, 165 chemin du grand revoyet, Pierre Bénite Cedex, France.

Background: Nivolumab is a fully human antibody which is routinely used at first therapy for metastatic melanoma. Usually, side effects are immune-related adverse events. We report a case of a man who developed bilateral anterior uveitis and macular serous retinal detachment during nivolumab treatment for metastatic melanoma. Read More

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https://bmcophthalmol.biomedcentral.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12886-017-0611-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709862PMC
December 2017
18 Reads

Clinical Features of CMV-Associated Anterior Uveitis.

Ocul Immunol Inflamm 2018 27;26(1):107-115. Epub 2017 Nov 27.

f DHU ViewRestore , University of Pierre and Marie Curie, Sorbonne Universités , Paris , France.

Cytomegalovirus (CMV) anterior uveitis is the most common ocular manifestation of CMV disease in immunocompetent individuals. It is thought to be due to a local reactivation of latent CMV and is usually unilateral. The acute form presents as Posner-Schlossman Syndrome, a recurrent hypertensive anterior uveitis with few granulomatous keratic precipitates. Read More

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http://dx.doi.org/10.1080/09273948.2017.1394471DOI Listing
August 2018
15 Reads

[Uveitis: Diagnostic work-up. Recommendations from an expert committee].

Rev Med Interne 2018 Sep 6;39(9):676-686. Epub 2017 Nov 6.

Service d'ophtalmologie, hôpital de la Croix-Rousse, hospices civils de Lyon, 103, grande rue de la Croix-Rousse, 69317 Lyon cedex 04, France.

Introduction: Diagnostic work-up of uveitis involves many uncertainties. Search for an etiology should take into account the epidemiology of uveitis and focus on the most severe diseases or those, which can be treated. This work was undertaken to establish recommendations for the diagnosis work-up of uveitis. Read More

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http://dx.doi.org/10.1016/j.revmed.2017.09.015DOI Listing
September 2018
4 Reads

Novel treatment regimen of Vogt-Koyanagi-Harada disease with a reduced dose of corticosteroids combined with immunosuppressive agents.

Curr Eye Res 2018 02 7;43(2):254-261. Epub 2017 Nov 7.

b University Eye Clinic Maastricht , Maastricht , The Netherlands.

Purpose: To investigate the effectiveness, visual outcome, and prognostic factors of Vogt-Koyanagi-Harada (VKH) disease treatment with a reduced dose of corticosteroids combined with immunosuppressive agents.

Methods: The clinical characteristics, auxiliary examinations, treatment result, visual outcome, and prognostic factors in VKH patients were analyzed.

Results: A total of 998 VKH patients were divided into posterior uveitis group (Group1), anterior uveal involvement group (Group 2), and recurrent granulomatous anterior uveitis group (Group 3). Read More

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http://dx.doi.org/10.1080/02713683.2017.1383444DOI Listing
February 2018
19 Reads

Leprosy Presenting with Iridocyclitis: A Diagnostic Dilemma.

J Ophthalmic Vis Res 2017 Oct-Dec;12(4):437-439

Department of Pathology, Uttar Pradesh University of Medical Sciences (U.P.U.M.S.), Saifai, Etawah, India.

Purpose: To report a case of lepromatous iridocyclitis that posed a diagnostic challenge.

Case Report: A 50-yeasr-old male developed profound loss of vision in the right eye, while he was in the hospital with septicemia presenting with fever, dysuria, and abdominal swelling. He also developed erythema nodosum on the legs. Read More

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http://dx.doi.org/10.4103/jovr.jovr_155_15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644414PMC
November 2017
7 Reads

[Current research of sympathetic ophthalmia].

Authors:
Y Di J J Ye

Zhonghua Yan Ke Za Zhi 2017 Oct;53(10):778-782

Department of Ophthalmology, Peking Union Medical Academy of Medical Sciences, Beijing 100730, China.

Sympathetic ophthalmia (SO) is a rare, bilateral, non-necrotizing, granulomatous uveitis that usually occurs after open ocular injury or intraocular surgery. The pathophysiology is not clearly understood, but generally SO is an immediate hypersensitivity mediated by T lymphocytes which are related to ocular tissue antigens. The main histopathological features are granulation tissues composed of lymphocytes, macrophages and multinucleated giant cells. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0412-4081.2017.10.013DOI Listing
October 2017

Uveitis: Diagnostic work-up. A literature review and recommendations from an expert committee.

Autoimmun Rev 2017 Dec 14;16(12):1254-1264. Epub 2017 Oct 14.

Service de Rhumatologie, Hôpital Saint-Antoine, AP-HP, UPMC Univ Paris 06, INSERM UMRS 938, DHU i2B, 75012 Paris, France.

Purpose: Diagnosis of uveitis is difficult. Etiologic investigations should take into account the epidemiology of uveitis and should focus on the most severe forms of the disease and those which can be treated. This study was undertaken to establish recommendations for the diagnosis of uveitis. Read More

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http://dx.doi.org/10.1016/j.autrev.2017.10.010DOI Listing
December 2017
18 Reads

The Choroidal Vascularity Index Decreases and Choroidal Thickness Increases in Vogt-Koyanagi-Harada Disease Patients During a Recurrent Anterior Uveitis Attack.

Ocul Immunol Inflamm 2018 15;26(8):1237-1243. Epub 2017 Sep 15.

a The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology and Chongqing Eye Institute , Chongqing , P.R. China.

Purpose: To measure changes in the choroidal vascularity index (CVI) in chronic Vogt-Koyanagi-Harada (VKH) disease during a recurrent anterior uveitis attack.

Methods: Forty VKH patients and 40 normal controls were included in this study. Choroidal images were recorded before and during a recurrent anterior uveitis attack, as well as after appropriate treatment. Read More

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http://dx.doi.org/10.1080/09273948.2017.1343357DOI Listing
December 2018
24 Reads
1.440 Impact Factor

Patterns of uveitis in children at the apex institute for eye care in India: analysis and review of literature.

Int Ophthalmol 2018 Oct 31;38(5):2061-2068. Epub 2017 Aug 31.

Retina and Uvea Services, Dr R P Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.

Aim: To study patterns of uveitis in Indian children and compare with data sets published earlier in the literature.

Methods: Consecutive patients below 16 years of age presenting to the uvea clinic of a tertiary eye care center were included prospectively through the period of July 2009-August 2013. Children with retinal vasculitis, exogenous endophthalmitis and masquerade syndromes were excluded from analysis. Read More

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http://dx.doi.org/10.1007/s10792-017-0700-6DOI Listing
October 2018
45 Reads

[Bilateral leptospiral anterior granulomatous uveitis: Case report].

J Fr Ophtalmol 2017 Sep 10;40(7):e247-e248. Epub 2017 Aug 10.

Service d'ophtalmologie, CHAR Rosemon, avenue des Flamboyants, 97306 Cayenne-Guyane, France.

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http://dx.doi.org/10.1016/j.jfo.2016.07.023DOI Listing
September 2017
2 Reads

Ocular syphilis: the re-establishment of an old disease.

Eye (Lond) 2018 01 4;32(1):99-103. Epub 2017 Aug 4.

Manchester Royal Eye Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK.

PurposeTo present the patient profiles, clinical presentations and visual outcomes in those diagnosed with ocular syphilis, attending a subspecialist uveitis service in northern England over a 15-year period.Patients and methodsRetrospective observational case series of patients presenting between January 2002 and December 2016.ResultsA total of 50 eyes of 34 patients had intraocular inflammation due to syphilis. Read More

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http://dx.doi.org/10.1038/eye.2017.155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770706PMC
January 2018
1 Read

Presumed tuberculosis-associated uveitis: rising incidence and widening criteria for diagnosis in a non-endemic area.

Eye (Lond) 2018 01 4;32(1):87-92. Epub 2017 Aug 4.

Manchester Royal Eye Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK.

PurposeTo assess the incidence, clinical ocular involvement and effectiveness of anti-tuberculous treatment in patients with chronic uveitis presumed to be associated with tuberculosis in a non-endemic community.Patients and methodsRetrospective case series of patients with uveitis and evidence of tuberculosis, with no other identified cause of uveitis, who underwent a 6-month course of standard anti-tuberculosis treatment between 2008 and 2015. The response to treatment was assessed at 6 and 12 months after initiation of treatment. Read More

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http://dx.doi.org/10.1038/eye.2017.152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770703PMC
January 2018
1 Read

Ocular manifestations as first signs of systemic T cell lymphoma in two cases.

BMC Ophthalmol 2017 Jun 23;17(1):99. Epub 2017 Jun 23.

Department of Ophthalmology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, 100730, China.

Background: Intraocular involvement of systemic T-cell lymphomas are uncommon and have been broadly regarded as markers of poor prognosis. We reported two cases of uveitis patients finally diagnosed as systemic T cell lymphoma.

Case Presentation: Case one is a 19-year-old female presented with fever and liver dysfunction, and was diagnosed as EBV-associated chronic active hepatitis. Read More

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http://dx.doi.org/10.1186/s12886-017-0494-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481994PMC
June 2017
2 Reads

Anticentromere antibody positive Ackerman's Syndrome with Granulomatous Anterior Uveitis.

Acta Reumatol Port 2017 Jul-Sep;42(3):277-278

Instituto Português de Reumatologia.

Ackerman's Syndrome or Intersticial Granulomatous Dermatitis with Arthritis has been an issue of increasing number of reports in the last decade which had focused its heterogeneous cutaneous and rheumatologic expression besides the initial manifestations reported by Ackerman and his group. Granulomatosis anterior uveitis has not been previously described. Some patients are reported to have positive autoantibodies but association with anticentromere antibodies has not been previously described as well, to our knowledge. Read More

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July 2018
18 Reads

Trematodal granulomatous uveitis in paediatric Egyptian patients: a case series.

Br J Ophthalmol 2017 08 9;101(8):999-1002. Epub 2017 Jun 9.

International Eye Clinic, Orouba Square, Souhag, Egypt.

Purpose: To describe the clinical presentations and results of laboratory analysis of waterborne ophthalmic granulomas of the anterior chamber (AC) in Egyptian patients.

Participants: 110 patients with granulomatous anterior uveitis and distinctive AC nodules.

Design: Prospective, non-comparative, case series. Read More

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http://dx.doi.org/10.1136/bjophthalmol-2017-310259DOI Listing
August 2017
4 Reads

Uveitis induced by programmed cell death protein 1 inhibitor therapy with nivolumab in metastatic melanoma patient.

J Infect Chemother 2017 Nov 18;23(11):774-777. Epub 2017 May 18.

Department of Dermatology, Gifu University Graduate School of Medicine, Gifu, Japan.

Nivolumab, a new immune checkpoint inhibitor, binds to programmed cell death-protein 1 receptors on T cell, blockades binding of its ligands, and augments the immunologic reaction against tumor cells. Augmented immune response, however, may lead to immune-related adverse events. Herein we describe a rare case of bilateral anterior uveitis induced by nivolumab treatment for metastatic melanoma. Read More

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http://dx.doi.org/10.1016/j.jiac.2017.04.007DOI Listing
November 2017
47 Reads

[Ocular sarcoidosis].

Z Rheumatol 2017 Jun;76(5):391-397

Augenklinik, Klinikum der Stadt Ludwigshafen am Rhein, Bremserstr. 79, 67063, Ludwigshafen, Deutschland.

Ocular manifestation of sarcoidosis occurs in up to 60% of patients with confirmed systemic sarcoidosis and represents one of the most common forms of noninfectious uveitis. In known pulmonary sarcoidosis, ocular involvement can occur in up to 80% of cases. Sarcoidosis can also present only in the eye, without a systemic manifestation (ocular sarcoidosis). Read More

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http://dx.doi.org/10.1007/s00393-017-0303-7DOI Listing
June 2017
10 Reads

The application of optical coherence tomography angiography in uveitis and inflammatory eye diseases.

Prog Retin Eye Res 2017 07 29;59:178-201. Epub 2017 Apr 29.

Cole Eye Institute, Cleveland Clinic, Cleveland, OH, USA.

Since its introduction in the early 1990s, optical coherence tomography (OCT) has evolved in resolution and technological advances, and in recent years its initial application of assessing the morphology of a tissue has been implemented by the study of its functional blood flow, through optical coherence tomography angiography (OCTA). This novel technique details capillary networks by comparing the amount of light returned from static and moving targets without the need for intravenous dye administration. While this imaging modality has been used for various ocular conditions, the application OCTA to uveitis conditions remains sparse. Read More

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http://dx.doi.org/10.1016/j.preteyeres.2017.04.005DOI Listing
July 2017
10 Reads

[Clinical features, risk factors and progresses on treatment of recurrent Vogt-Koyanagi-Harada disease].

Zhonghua Yan Ke Za Zhi 2017 Apr;53(4):317-320

Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.

Vogt-Koyanagi-Harada disease(VKH) is a bilateral, granulomatous panuveitis associated with central nervous system, auditory, and integumentary manifestations. Clinically, VKH usually responds well to early aggressive glucocorticosteroid treatment and may be cured without any clinically significant sequelae. Some patients, however, may enter the chronic recurrent phase, which may result in marked loss of vision due to complications such as complicated cataract, secondary glaucoma and maculopathy. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0412-4081.2017.04.017DOI Listing
April 2017
28 Reads

Rare Clinical Sign of Hodgkin's Lymphoma: Ocular Involvement.

Turk J Ophthalmol 2017 Apr 1;47(2):110-112. Epub 2017 Apr 1.

Dokuz Eylül University Faculty of Medicine, Department of Ophthalmology, İzmir, Turkey.

Bilateral non-granulomatous anterior uveitis with left vitritis and macular edema were detected in a 19-year-old woman presenting with blurred vision in her left eye. Light microscopic study of the pathologic mediastinal lymph node that was detected via contrast computed tomography imaging during etiologic study revealed nodular sclerosing and mixed cellularity Hodgkin's lymphoma (HL). Ocular findings completely resolved with adriablastin, bleomycin, vinblastine, dacarbazine chemotherapy treatment. Read More

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http://dx.doi.org/10.4274/tjo.92609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384116PMC
April 2017
12 Reads

Management of Uveitis and Scleritis in Necrobiotic Xanthogranuloma.

J Ocul Pharmacol Ther 2017 05 10;33(4):325-333. Epub 2017 Apr 10.

1 F.I. Proctor Foundation, University of California , San Francisco, San Francisco, California.

Necrobiotic xanthogranuloma (NXG) is a chronic, progressive non-Langerhans histiocytic granulomatous disease. While case reports describing periorbital involvement of NXG are frequent, only a few case reports describing ocular involvement, such as scleritis and uveitis, exist. Herein, we present a case presenting initially as bilateral anterior and posterior scleritis, as well as a chronic bilateral granulomatous panuveitis, and discuss the immunosuppressant options that should be considered for this disease with protean manifestations. Read More

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http://dx.doi.org/10.1089/jop.2016.0135DOI Listing
May 2017
4 Reads

Unilateral uveitis associated with IgA nephropathy.

Arch Soc Esp Oftalmol 2017 Dec 23;92(12):598-601. Epub 2017 Mar 23.

Oftalmología, Hospital Universitario Virgen del Rocío, Sevilla, España.

Case Report: The case is presented of a 42 year-old man with episodes of unilateral uveitis in his right eye. Ophthalmic examination showed a granulomatous anterior uveitis with vitritis. Systemic investigations revealed non-nephrotic proteinuria and microhaematuria. Read More

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http://dx.doi.org/10.1016/j.oftal.2017.02.006DOI Listing
December 2017
3 Reads