981 results match your criteria Uterus Mullerian Duct Abnormalities


Retinoic acid signaling determines the fate of the uterus from the mouse Müllerian duct.

Reprod Toxicol 2019 Mar 30;86:56-61. Epub 2019 Mar 30.

Graduate School of Nanobioscience, Yokohama City University, Yokohama 236-0027, Japan. Electronic address:

In female mice, the Müllerian duct develops into the oviduct, uterus and vagina. The fate of epithelia is determined by factors secreted from the mesenchyme. Retinoic acid (RA) and its receptors are present in the mesenchyme of cranial Müllerian duct. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.reprotox.2019.03.006DOI Listing
March 2019
4 Reads

Abnormal hysteroscopy findings among a cross section of infertile Nigerian women.

Niger J Clin Pract 2019 Jan;22(1):9-15

Department of Obstetrics and Gynaecology, University of Portharcout Teaching Hospital, Port Harcourt, Nigeria.

Background: Intrauterine lesions are important causes of infertility. This study aims to evaluate the abnormal findings at hysteroscopy among infertile women seen in 2 new Fertility/Gynaecological Endoscopy units in Nigeria.

Methods: A prospective study of 159 infertile women who had diagnostic hysteroscopy in Nnamdi Azikiwe University Teaching hospital Nnewi and Holy Rosary Specialist Hospital, Onitsha to evaluate the intrauterine lesions seen. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/njcp.njcp_404_17DOI Listing
January 2019
8 Reads

Double Cervix with Normal Uterus and Vagina - An Unclassified Müllerian Anomaly.

Int J Fertil Steril 2019 Apr 6;13(1):83-85. Epub 2019 Jan 6.

Gynaecology and Obstetrics Senior Consultant, Hospital Garcia de Orta, Almada, Portugal.

Müllerian anomalies are very common, and a frequent cause of infertility. The most used classification system until now, proposed by the American Society for Reproductive Medicine in 1988, categorizes comprehensively uterine anomalies but fails to classify defects of the cervix or vagina. This is based on a developmental theory that postulates that müllerian duct fusion is unidirectional, beginning caudally and extending cranially, which does not account for isolated cervical or vaginal defects. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.22074/ijfs.2019.5524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334021PMC
April 2019
5 Reads

Successful preterm pregnancy in a rare variation of Herlyn-Werner-Wunderlich syndrome: a case report.

BMC Pregnancy Childbirth 2018 Dec 17;18(1):498. Epub 2018 Dec 17.

Department of Woman's and Child's Health, Obstetrics and Gynecological Unit, San Camillo-Forlanini Hospital, Circonvallazione Gianicolense 87, 00152, Rome, Italy.

Background: Herlyn-Werner-Wunderlich syndrome (HWWS) is an uncommon congenital anomaly of the female urogenital tract, characterised by uterus didelphys, obstructed hemivagina, and ipsilateral renal agenesis. We reported the difficult pregnancy course complicated by an extremely rare and unique case of this syndrome associated with ectrodactyly, a clinical combination never described in literature.

Case Presentation: A 28- year-old nulliparous woman previously diagnosed for HWWS associated with ectrodactyly of the right foot and with a history of abdominal left hemi-hysterectomy, ipsilateral salpingectomy, vaginal reconstruction when she was an adolescent. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12884-018-2133-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296152PMC
December 2018
7 Reads

Transverse testicular ectopia associated with persistent Müllerian duct syndrome treated by transseptal orchiopexy: A case report.

Medicine (Baltimore) 2018 Nov;97(48):e13305

Departments of Urology.

Rationale: Persistent Müllerian duct syndrome (PMDS) is rare form of male pseudohermaphroditism characterized by the presence of uterus and fallopian tubes with normal external genitalia and secondary sexual characteristics. Transverse testicular ectopia (TTE) is also a rare form of testicular ectopia that may be associated with PMDS.

Patient Concerns: We present a 2-year-old boy who presented with bilateral non-palpable testes with left inguinal mass. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000013305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283222PMC
November 2018
4 Reads

Müllerian Aplasia with Severe Hematometra: A Case Report of Diagnosis and Management in a Low Resource Setting.

J Pediatr Adolesc Gynecol 2019 Apr 22;32(2):189-192. Epub 2018 Nov 22.

Department of Obstetrics and Gynecology, University of Iowa, Carver College of Medicine, Iowa City, Iowa.

Background: Müllerian aplasia or Mayer-Rokitansky-Küster-Hauser syndrome is described as congenital absence of the proximal vagina with or without absence of the cervix and uterus, most often recognized after the onset of primary amenorrhea.

Case: An 18-year-old woman presented to a free medical clinic in Arcahaie, Haiti with primary amenorrhea, abdominal distention, and cyclic monthly abdominal pain. Physical exam was significant for uterus palpable superior to the umbilicus, absence of vagina, and rectal exam without palpable vagina or cervix. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10833188183035
Publisher Site
http://dx.doi.org/10.1016/j.jpag.2018.11.006DOI Listing
April 2019
11 Reads

Congenital anal atresia with rectovestibular fistula, scoliosis, unilateral renal agenesis, and finger defect (VACTERL association) in a patient with partial bicornuate uterus and distal vaginal atresia: A case report.

Medicine (Baltimore) 2018 Nov;97(45):e12822

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, P. R. of China.

Rationale: Vertebral defect, anal atresia, cardiac defect, tracheoesophageal fistula/esophageal atresia, renal defect, and limb defect (VACTERL) association and Müllerian duct anomalies are rare conditions. We present a rare condition with the co-occurrence of the VACTERL association and Müllerian duct hypoplasia to characterize patients' clinical presentations, outcomes, and treatment.

Patient Concerns: An 11-year-old girl presented to our hospital with severe lower abdominal pain, lower vaginal atresia with enlargement of the upper vagina and a bicornuate uterus with a Y-shaped uterine cavity filled with hematometra on pelvic magnetic resonance imaging. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000012822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250493PMC
November 2018
12 Reads

An Atypical Presentation of Ectopic Pregnancy With Unicornuate Uterus and Undescended Fallopian Tube.

J Obstet Gynaecol Can 2019 Feb 30;41(2):214-216. Epub 2018 Oct 30.

Department of Obstetrics and Gynecology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB.

Background: Müllerian duct abnormalities are common and may be related to pregnancy complications. Few cases of ectopic pregnancy within an undescended Fallopian tube have been reported, and they present a diagnostic challenge.

Case: A 32-year-old pregnant woman had three presentations to the emergency department for increasing left upper abdominal pain, chest pain, shortness of breath, and eventual hemodynamic instability in the setting of right unicornuate uterus and undiagnosed undescended left adnexa. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jogc.2018.08.013DOI Listing
February 2019
4 Reads

Severe incomplete fusion of the Müllerian ducts influences reproduction in Holstein cattle.

Theriogenology 2019 Jan 28;123:209-215. Epub 2018 Sep 28.

Laboratory of Theriogenology, Department of Veterinary Medical Sciences, Graduate School of Agriculture and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.

Fusion failure of the Müllerian ducts is thought to occur congenitally in cattle. We aimed to elucidate the contribution of incomplete fusion of the Müllerian ducts to reproductive difficulties in dairy cattle. We observed the vaginas of Holstein cattle to classify the anomalies into mild and severe types, based on severity of incomplete fusion, and recorded information about the cattle at the time of artificial insemination (AI) or embryo transfer. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S0093691X183087
Publisher Site
http://dx.doi.org/10.1016/j.theriogenology.2018.09.035DOI Listing
January 2019
6 Reads

Three-dimensional scan of the uterine cavity of infertile women before assisted reproductive technology use.

Medicine (Baltimore) 2018 Oct;97(41):e12764

Department of Medical and Surgical Specialties, Faculty of Medicine, "Transilvania" University of Brasov, Brasov.

The primary objective was to assess the utility of routine 3-dimensional (3D) ultrasound in the evaluation of infertile women and to estimate the prevalence of uterine anomalies before the use of assisted reproductive technology (ART), using the European Society of Human Reproduction and Embryology and the European Society for Gynaecological Endoscopy classification system. A second objective was to assess the effect of uterine anomalies on the pregnancy rate in patients who underwent assisted reproductive techniques.We retrospectively studied 668 patients treated in the Department Obstetrics Gynecology and Neonatology "Sf Ioan" Clinical Emergency Hospital and in the Department of Medical and Surgical Specialties, Faculty of Medicine "'Transilvania" University of Brasov between July 2016 and February 2017 for subfertility. Read More

View Article

Download full-text PDF

Source
http://Insights.ovid.com/crossref?an=00005792-201810120-0006
Publisher Site
http://dx.doi.org/10.1097/MD.0000000000012764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203555PMC
October 2018
5 Reads

Case 29-2018: A 31-Year-Old Woman with Infertility.

N Engl J Med 2018 Sep;379(12):1162-1172

From the Department of Obstetrics and Gynecology, Hospital of the University of Pennsylvania, and the Department of Obstetrics and Gynecology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia (C.C.); and the Departments of Radiology (A.K.), Urology (A.S.F.), Obstetrics and Gynecology (M.E.S.), and Pathology (E.O.), Massachusetts General Hospital, and the Departments of Radiology (A.K.), Surgery (A.S.F.), Obstetrics and Gynecology (M.E.S.), and Pathology (E.O.), Harvard Medical School - both in Boston.

View Article

Download full-text PDF

Source
http://www.nejm.org/doi/10.1056/NEJMcpc1807497
Publisher Site
http://dx.doi.org/10.1056/NEJMcpc1807497DOI Listing
September 2018
16 Reads

Primary cervico-uterine anastomosis in a patient with agenesis of the uterine isthmus: A case report and review.

J Obstet Gynaecol Res 2018 Dec 9;44(12):2199-2203. Epub 2018 Sep 9.

Department of Obstetrics and Gynecology, Texas Tech University Health Sciences Center, Lubbock, Texas, USA.

Arrested caudal extension of the fused Müllerian ducts, either complete or segmental, causes obstruction of the outflow tract. We describe a case of agenesis of the uterine isthmus and the procedure to establish the continuity of the outflow tract. A 15-year-old girl with cyclic pelvic pain and amenorrhea was found to have a 3-cm gap between the uterine body and the cervix. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jog.13779DOI Listing
December 2018
11 Reads

Advanced Imaging for the Diagnosis and Treatment of Coexistent Renal and Müllerian Abnormalities.

Curr Urol Rep 2018 Sep 6;19(11):89. Epub 2018 Sep 6.

Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL, USA.

Purpose Of Review: Abnormal development of the uterus, cervix, and proximal 2/3 of the vagina results in Müllerian duct anomalies. Because of the close embryologic relationship between the developing female genital and urinary tracts, abnormalities of the urinary tract often accompany Müllerian duct anomalies. Magnetic resonance imaging (MRI) is the current gold standard-imaging modality in the evaluation of the anomalies of the female reproductive tract. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11934-018-0840-xDOI Listing
September 2018
12 Reads

[Value of MRI in the pre-operative diagnosis and classification of oblique vaginal septum syndrome].

Zhonghua Fu Chan Ke Za Zhi 2018 Aug;53(8):534-539

Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.

To explore the role of MRI in the pre-operative diagnosis and classification of oblique vaginal septum syndrome (OVSS) . A retrospective analysis of the clinical records and pre-operative MRI images of 19 patients with surgery proved OVSS was carried out. Two experienced radiologists reviewed the pre-operative pelvic MRI of the 19 patients in consensus blind to the surgery results. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3760/cma.j.issn.0529-567x.2018.08.005DOI Listing
August 2018
13 Reads

Use of infragluteal folds as a full-thickness skin graft donor site for construction of the neovagina in cases of Mullerian agenesis.

J Obstet Gynaecol Res 2018 Oct 16;44(10):1985-1994. Epub 2018 Aug 16.

Department of Plastic, Reconstructive, and Aesthetic Surgery, Erciyes University, School of Medicine, Kayseri, Turkey.

Aim: The aims of this study were to present the results of using infragluteal folds as a skin graft donor site in cases of Mullerian agenesis undergoing full-thickness skin graft vaginoplasty and to evaluate the outcomes of the surgical technique.

Methods: Demographics and clinical parameters of 24 consecutive Mullerian agenesis patients refusing any dilatational procedure and undergoing neovaginal construction using infragluteal folds skin grafts from May 2004 to July 2015 were analyzed.

Results: The mean age of the patients was 21. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jog.13752DOI Listing
October 2018
19 Reads

Search for altered imprinting marks in Mayer-Rokitansky-Küster-Hauser patients.

Mol Genet Genomic Med 2018 11 11;6(6):1225-1228. Epub 2018 Aug 11.

Institute of Human Genetics, University of Münster, Münster, Germany.

Background: Mayer-Rokitansky-Küster-Hauser syndrome (MRKH) is the second most common cause of primary amenorrhea and characterized by absence of the uterus and the upper part of the vagina. The etiology of MRKH is mainly unknown but a contribution of genomic alterations is probable. A molecular disturbance so far neglected in MRKH research is aberrant methylation at imprinted loci. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/mgg3.426
Publisher Site
http://dx.doi.org/10.1002/mgg3.426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305658PMC
November 2018
9 Reads

Using 3D MRI can potentially enhance the ability of trained surgeons to more precisely diagnose Mullerian duct anomalies compared to MR alone.

Eur J Obstet Gynecol Reprod Biol 2018 Sep 9;228:313-318. Epub 2018 Jul 9.

Department of Obstetrics and Gynecology, Nan Fang Hospital of Southern Medical University, Guangzhou, Guangdong 510515, PR China. Electronic address:

Objective: The aim of this study was to examine if the advanced tool of 3D MRI model provides more precise information on the anatomy of pelvic organs than MRI alone, and compare to clinical and operative finding of patients with vagina in Müllerian duct anomalies.

Study Design: One hundred and ten patients with clinically and operatively proven Müllerian duct anomalies were included. The consistency of diagnosis of Mullerian tract anomalies by MRI and 3D MRI compared to clinically and surgically proven anomalies defined according to ASRM classification. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejogrb.2018.07.007DOI Listing
September 2018
23 Reads

Successful Pregnancy Outcome after Open Strassman Metroplasty for Bicornuate Uterus.

Case Rep Obstet Gynecol 2018 31;2018:4579736. Epub 2018 May 31.

Aga Khan University Hospital, Nairobi, Kenya.

Introduction: Müllerian duct anomalies represent a group of congenital malformations that result from failure to complete bilateral paramesonephric duct elongation, fusion, canalization, or septal resorption. These anomalies are rare in the general population with a bicornuate or didelphys uterus being among the common ones. Bicornuate uterine malformations are of clinical significance due to their adverse reproductive outcomes. Read More

View Article

Download full-text PDF

Source
https://www.hindawi.com/journals/criog/2018/4579736/
Publisher Site
http://dx.doi.org/10.1155/2018/4579736DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029456PMC
May 2018
6 Reads

Reproductive outcomes in women with unicornuate uterus undergoing in vitro fertilization: a nested case-control retrospective study.

Reprod Biol Endocrinol 2018 Jul 6;16(1):64. Epub 2018 Jul 6.

Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, 100191, China.

Background: Unicornuate uterus, a congenital uterine malformation resulting from unilateral maldevelopment of Mullerian duct, is more prevalent in women with infertility. Owing to relative rarity of the condition, the evidence on the associated reproductive outcomes is derived from small heterogeneous studies that report different clinical endpoints and often do not account for the anatomical variations of unicornuate uterus. The aim of this study was to evaluate the embryological and clinical outcomes following IVF-ICSI treatment in women with unicornuate uterus without rudimentary functional cavity (ESHRE-ESGE class IVb). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12958-018-0382-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034283PMC
July 2018
7 Reads
2.410 Impact Factor

An unusual case of Herlyn-Werner-Wunderlich syndrome with a complete septate uterus and complicated urinary tract with rare ectopic ureteral opening.

Int J Gynaecol Obstet 2018 11 14;143(2):248-250. Epub 2018 Jul 14.

Department of Gynecology, Third Xiangya Hospital of Central South University, Changsha City, Hunan Province, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ijgo.12578DOI Listing
November 2018
4 Reads

The Interest of Women with Mayer-Rokitansky-Küster-Hauser Syndrome and Laparoscopic Vecchietti Neovagina in Uterus Transplantation.

J Pediatr Adolesc Gynecol 2018 Oct 8;31(5):480-484. Epub 2018 May 8.

Transplant Surgery Department, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.

Study Objective: The goal of this study was to assess a group of women with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome with surgically created neovaginas in the interest of uterus transplantation (UTx) and to recruit the first group of applicants for a UTx trial.

Design And Setting: This was an original prospective study using semistructured interviews.

Participants: A study group of 50 women with MRKH syndrome with Vecchietti neovaginas was recruited via letter of invitation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpag.2018.04.007DOI Listing
October 2018
15 Reads

Pelvic dystopia of right rudimentary multicystic dysplastic kidney as a rare cause of bedwetting in a patient with a single pelvic ectopic left kidney, and agenesis of the uterus and vagina (Mayer-Rokitansky-Küster-Hauser syndrome): a case report.

J Med Case Rep 2018 May 7;12(1):121. Epub 2018 May 7.

AkhmetYassawi International Kazakh-Turkish University, Clinical Diagnostic Center, Turkestan, Kazakhstan.

Background: Pelvic dystopia of rudimentary multicystic dysplastic kidney as a rare cause of bedwetting in children.

Case Presentation: We report the case of a 14-year-old Kazakh girl who presented with difficulty in starting the stream of urine and intermittent interruption of the urinary stream while voiding as well as bedwetting, caused by a rare congenital disease (pelvic dystopia of rudimentary multicystic dysplastic kidney). The diagnostic workup, differential diagnosis, and management, and a review of the literature are presented. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13256-018-1644-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937041PMC
May 2018
5 Reads

Uterus Septus Subtotalis Bicollis: A Rare Mullerian Duct Abnormality.

Ann Clin Lab Sci 2018 Jan;48(1):116-119

Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX

Mullerian duct anomalies (MDAs) are congenital defects of the female genital system that arise from abnormal embryological development of the Mullerian ducts. Septate uterus is the most common, resulting from incomplete resorption of the medial septum after fusion of the Mullerian ducts. Two main types of septate uterus exist, including septa that extend completely or partially from the uterine fundus to the cervical os. Read More

View Article

Download full-text PDF

Source
January 2018
9 Reads

Laparoscopic en bloc resection of a para-cervical cancer with OHVIRA syndrome.

Taiwan J Obstet Gynecol 2018 Feb;57(1):141-143

Department of Obstetrics and Gynecology, University of Perpetual Help Las Pinas and De La Salle University Medical Center, Cavite, Philippines. Electronic address:

Objective: There are some reports of cervical cancer with uterus didelphys but a case of clear cell carcinoma (CCCC) with Obstructed Hemivagina and Ipsilateral Renal Anomaly (OHVIRA) syndrome is extremely rare. The aim of this paper was to report a case of CCCC with OHVIRA syndrome and the difficulty in making a preoperative diagnosis.

Case Report: A 65 years old woman presented with postmenopausal bleeding and pelvic examination showed right paracervical mass. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tjog.2017.12.024DOI Listing
February 2018
3 Reads

[Unicornuate uterus with cavitary non-communicating rudimentary horn: magnetic resonance characterization].

Rev Med Inst Mex Seguro Soc 2018 Jan-Feb;56(1):92-97

Curso de Alta Especialidad en Resonancia Magnética de Cuerpo Completo, Hospital Ángeles del Pedregal, Ciudad de México, México.

Mullerian duct or paramesonephric anomalies are a group of congenital malformations of the female genital tract that result from the alteration in one or more stages of embryonic development. The prevalence has increased, probably due to the progress of diagnostic imaging methods and the relevance that it has acquired in young women with infertility problems. Magnetic resonance imaging (MRI) is currently the method of choice for characterizing the different types of Mullerian anomalies, its complications and associated pathology. Read More

View Article

Download full-text PDF

Source
August 2018
8 Reads

ACOG Committee Opinion No. 728: Müllerian Agenesis: Diagnosis, Management, And Treatment.

Authors:

Obstet Gynecol 2018 01;131(1):e35-e42

Müllerian agenesis, also referred to as müllerian aplasia, Mayer-Rokitansky-Küster-Hauser syndrome, or vaginal agenesis, has an incidence of 1 per 4,500-5,000 females. Müllerian agenesis is caused by embryologic underdevelopment of the müllerian duct, with resultant agenesis or atresia of the vagina, uterus, or both. Patients with müllerian agenesis usually are identified when they are evaluated for primary amenorrhea with otherwise typical growth and pubertal development. Read More

View Article

Download full-text PDF

Source
http://Insights.ovid.com/crossref?an=00006250-201801000-0004
Publisher Site
http://dx.doi.org/10.1097/AOG.0000000000002458DOI Listing
January 2018
11 Reads

ACOG Committee Opinion No. 728 Summary: Müllerian Agenesis: Diagnosis, Management, And Treatment.

Authors:

Obstet Gynecol 2018 01;131(1):196-197

Müllerian agenesis, also referred to as müllerian aplasia, Mayer-Rokitansky-Küster-Hauser syndrome, or vaginal agenesis, has an incidence of 1 per 4,500-5,000 females. Müllerian agenesis is cau0073ed by embryologic underdevelopment of the müllerian duct, with resultant agenesis or atresia of the vagina, uterus, or both. Patients with müllerian agenesis usually are identified when they are evaluated for primary amenorrhea with otherwise typical growth and pubertal development. Read More

View Article

Download full-text PDF

Source
http://Insights.ovid.com/crossref?an=00006250-201801000-0003
Publisher Site
http://dx.doi.org/10.1097/AOG.0000000000002452DOI Listing
January 2018
16 Reads

A novel mutation of HOXA11 in a patient with septate uterus.

Orphanet J Rare Dis 2017 12 11;12(1):178. Epub 2017 Dec 11.

National Research Institute for Family Planning, Beijing, 100081, People's Republic of China.

Background: The etiology of Müllerian duct anomalies (MDAs) is poorly understood at present. The HOXA11 gene is crucial for the development of the Müllerian duct. The objective of this study is to report a unique case of MDAs with a novel mutation in HOXA11. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13023-017-0727-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725892PMC
December 2017
9 Reads

Hyperandrogenemia and ovarian reserve in patients with Mayer-Rokitansky-Küster-Hauser syndrome type 1 and 2: potential influences on ovarian stimulation.

Arch Gynecol Obstet 2018 02 24;297(2):513-520. Epub 2017 Nov 24.

Department of Women's Health, Center for Rare Female Genital Malformations, Women's University Hospital, Tuebingen University Hospital, Calwerstr. 7, 72076, Tuebingen, Germany.

Purpose: This study aimed to analyze the hormone profiles, to detect the rate of hyperandrogenemia and to investigate the potential effect of Mayer-Rokitansky-Küster-Hauser syndrome (MRKHS) on ovarian reserve, as reflected by the serum Anti-Mullerian hormone (AMH) levels. Clinical implications were analyzed by including our own experiences with three patients after ovarian stimulation in preparation for uterus transplantation.

Methods: Serum samples of 100 patients with MRKHS (50 patients with MRKHS type 1 and 50 with type 2) were analyzed and compared to 50 individually age-matched healthy controls. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00404-017-4596-1DOI Listing
February 2018
12 Reads

Prostatic adenocarcinoma in the setting of persistent müllerian duct syndrome: a case report.

Hum Pathol 2018 05 12;75:125-131. Epub 2017 Nov 12.

Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Weill Medical College of Cornell University, Houston, 77030, TX. Electronic address:

Persistent müllerian duct syndrome (PMDS) is a form of disordered sex development in which rudimentary müllerian structures are identified in phenotypically and genotypically normal males. It is caused by defects in the anti-müllerian hormone (AMH) system. Since patients with PMDS present with undescended testes, testosterone production by Leydig cells later in life is often decreased. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00468177173041
Publisher Site
http://dx.doi.org/10.1016/j.humpath.2017.10.033DOI Listing
May 2018
5 Reads

Starting a uterus transplantation service: notes from a small island.

BJOG 2018 Mar 17;125(4):404-406. Epub 2017 Nov 17.

Department of Obstetrics and Gynecology, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/1471-0528.14968DOI Listing
March 2018
1 Read

Obstructive Müllerian Anomalies in Menstruating Adolescent Girls: A Report of 22 Cases.

J Pediatr Adolesc Gynecol 2018 Jun 10;31(3):252-257. Epub 2017 Oct 10.

Division of Gynecology, Department of Perinatology and Gynecology, Poznań University of Medical Sciences, Poznań, Poland.

Study Objective: To assess the clinical course of obstructive Müllerian anomalies found in girls after menarche.

Design: A retrospective case series of adolescents who, between 2009 and 2016, were treated for vaginal or uterine obstructive malformations diagnosed after menarche.

Setting: Division of Gynecology, Poznań University of Medical Sciences, Poznań, Poland. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpag.2017.09.013DOI Listing
June 2018
30 Reads

Congenital Uterine Malformation by Experts (CUME): better criteria for distinguishing between normal/arcuate and septate uterus?

Ultrasound Obstet Gynecol 2018 01;51(1):101-109

University College London Hospital, London, UK.

Objectives: To assess the level of agreement between experts in distinguishing between septate and normal/arcuate uterus using their subjective judgment when reviewing the coronal view of the uterus from three-dimensional ultrasound. Another aim was to determine the interobserver reliability and diagnostic test accuracy of three measurements suggested by recent guidelines, using as reference standard the decision made most often by experts (Congenital Uterine Malformation by Experts (CUME)).

Methods: Images of the coronal plane of the uterus from 100 women with suspected fundal internal indentation were anonymized and provided to 15 experts (five clinicians, five surgeons and five sonologists). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/uog.18923DOI Listing
January 2018
29 Reads

Transverse Vaginal Septum: Report of Two Patients with MRI Findings.

J Coll Physicians Surg Pak 2017 Sep;27(9):S74-S76

Department of Obstetrics and Gynecology, The Aga Khan University Hospital, Karachi.

The transverse vaginal septum is a rare form of Mullerian duct anomaly, and is a disorder of vertical fusion of Mullerian system with the sinovaginal bulb. Magnetic resonance imaging (MRI)is very useful in the detection, classification and management planning of this rare anomaly. We present two cases of transverse vaginal septum in two patients of different age groups and with different clinical presentations. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/263DOI Listing
September 2017
9 Reads

An overview of the results of hysterosonography prior to in vitro fertilization.

JBRA Assist Reprod 2017 12 1;21(4):302-305. Epub 2017 Dec 1.

CENAFERT - Salvador, BA, Brazil.

Objective: This study aimed to analyze the results of hysterosonography performed prior to in vitro fertilization (IVF) and to correlate anomalous findings with hysteroscopy.

Methods: Findings from 197 hysterosonograms of patients examined in an assisted reproduction clinic between January 2012 and August 2014 were included. Enrollment criteria: patients in preparation for IVF not recently submitted to uterine examination through hysterosalpingography or hysteroscopy referred to hysterosonography. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5935/1518-0557.20170051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714596PMC
December 2017
51 Reads

Young Girl With Abdominal Pain.

Ann Emerg Med 2017 Oct;70(4):e39-e40

Department of Emergency Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan; Department of Emergency Medicine, Chung Shan Medical University, Taichung, Taiwan; Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.annemergmed.2017.04.025DOI Listing
October 2017
50 Reads

Successful Vaginal Delivery of Naturally Conceived Dicavitary Twin in Didelphys Uterus: A Rare Reported Case.

Case Rep Obstet Gynecol 2017 27;2017:7279548. Epub 2017 Aug 27.

Department of Obstetrics and Gynaecology, Ibri Regional Hospital, Ministry of Health, Ibri, Oman.

Didelphys uterus, or double uterus, is an embryological developmental malformation of the müllerian ducts with the incidence of approximately 8.3% of all müllerian duct abnormalities (MDAs). Didelphys uterus accompanying dicavitary twin gestation is encountered as a very rare entity with overall incidence of about 1 in 1,000,000. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2017/7279548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591991PMC
August 2017
34 Reads

Mayer-Rokitansky-Küster-Hauser Syndrome With Bilateral Ovarian Sertoli Cell Tumors: Review of the Literature and Report of a Rare Case.

Female Pelvic Med Reconstr Surg 2018 Sep/Oct;24(5):e32-e34

Private Obstetrics and Gynecology Practice, Irvington, NJ.

Background: Patients with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome are infertile secondary to hypoplasia or complete agenesis of the uterus, yet they remain at risk of primary neoplasms of the ovaries because embryologically the uterus and ovaries develop via separate mechanisms.

Case: A 72-year-old nulliparous woman with a history of primary amenorrhea underwent an exploratory laparotomy for a suspected uterine fibroid. In addition to the pelvic mass, the patient was found to have findings consistent with MRKH syndrome. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/SPV.0000000000000483DOI Listing
April 2019
5 Reads

The spectrum of imaging appearances of müllerian duct anomalies: focus on MR imaging.

Jpn J Radiol 2017 Dec 18;35(12):697-706. Epub 2017 Sep 18.

Division of Radiology, Department of Pathophysiological and Therapeutic Science, Faculty of Medicine, Tottori University, 36-1 Nishi-cho, Yonago, Tottori, 683-8504, Japan.

Müllerian duct anomalies (MDAs) are the result of incomplete development, vertical or lateral fusion, or absorption of the müllerian ducts. The range of anomalies includes uterovaginal agenesis or hypoplasia, unicornuate uterus, uterus didelphys, bicornuate uterus, septate uterus, and arcuate uterus. Correct diagnosis and classification of these anomalies are essential because pregnancy outcomes and treatment options vary between the types of anomaly. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s11604-017-0681-4
Publisher Site
http://dx.doi.org/10.1007/s11604-017-0681-4DOI Listing
December 2017
15 Reads

Müllerian Agenesis in Cat Eye Syndrome and 22q11 Chromosome Abnormalities: A Case Report and Literature Review.

J Pediatr Adolesc Gynecol 2018 Apr 14;31(2):158-161. Epub 2017 Sep 14.

Hamilton Regional Laboratory Medicine Program, Hamilton Health Sciences, Hamilton, Ontario, Canada; Department Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.

Background: Although Müllerian agenesis is the second most common cause of primary amenorrhea the underlying etiology in most cases is unknown. Müllerian agenesis has been reported as a rare finding associated with chromosomal aberrations of the 22q11 chromosomal region including at least 1 individual with cat eye syndrome (CES) and 10 individuals with deletions or duplications of the 22q11.2 region. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10833188173045
Publisher Site
http://dx.doi.org/10.1016/j.jpag.2017.09.004DOI Listing
April 2018
30 Reads

Importance of Serum Testicular Protein Hormone Measurement in the Assessment of Disorders of Sex Development.

Sex Dev 2018 30;12(1-3):30-40. Epub 2017 Aug 30.

Centro de Investigaciones Endocrinológicas 'Dr. César Bergadá' (CEDIE), CONICET - FEI - División de Endocrinología, Hospital de Niños Ricardo Gutiérrez, Buenos Aires, Argentina.

Commonly known for testosterone secretion, the testes also produce the protein hormones anti-müllerian hormone (AMH), inhibin B, and insulin-like factor 3 (INSL3). AMH and inhibin B are secreted by Sertoli cells, whereas INSL3 is a Leydig cell product. AMH is involved in fetal sex differentiation and induces the regression of the anlagen of the uterus and fallopian tubes. Read More

View Article

Download full-text PDF

Source
https://www.karger.com/Article/FullText/479572
Publisher Site
http://dx.doi.org/10.1159/000479572DOI Listing
November 2018
4 Reads

Pregnancy outcomes of women with a congenital unicornuate uterus after IVF-embryo transfer.

Reprod Biomed Online 2017 Nov 3;35(5):583-591. Epub 2017 Aug 3.

Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha City, Hunan 410078, China; Institute of Reproductive and Stem Cell Engineering, Central South University, Changsha City, Hunan 410078, China. Electronic address:

Unicornuate uteri are caused by non-development of one Müllerian duct. The objective of this study was to investigate pregnancy outcomes of singleton and/or twin pregnancies in women with unicornuate uterus after IVF-embryo transfer (IVF-ET). The study group comprised 238 patients with a unicornuate uterus and the control group 818 patients with normal uterus. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.rbmo.2017.07.015DOI Listing
November 2017
9 Reads

Secondary dysmenorrhea due to a rudimentary, non-communicating functional uterine horn.

Ginekol Pol 2017 ;88(7):404-405

3rd Department of Gynecology, ul.Jaczewskiego 8, 20-954, Lublin, Poland.

Unicornuate uterus with a rudimentary horn is a rare congenital Müllerian anomaly, which may lead to many obstetrical and gynaecological complications. This pathology occurs in approximately 1/100 000 women. A rudimentary horn forms due to insufficient development of the Müllerian duct. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5603/GP.a2017.0075DOI Listing
July 2018
3 Reads

Sequence variants in ESR1 and OXTR are associated with Mayer-Rokitansky-Küster-Hauser syndrome.

Acta Obstet Gynecol Scand 2017 Nov 21;96(11):1338-1346. Epub 2017 Sep 21.

Department of Women's Health, Center for Rare Female Genital Malformations, Women's University Hospital, Tübingen University Hospital, Tübingen, Germany.

Introduction: Mayer-Rokitansky-Küster-Hauser syndrome (MRKHS) is characterized by congenital absence of the uterus and the upper two-thirds of the vagina in otherwise phenotypically normal females. It is found isolated or associated with renal, skeletal and other malformations. Despite ongoing research, the etiology is mainly unknown. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/aogs.13202DOI Listing
November 2017
31 Reads

Müllerian anomaly in a woman with Hirschsprung's disease.

BMJ Case Rep 2017 Aug 7;2017. Epub 2017 Aug 7.

Department of Obstetrics and Gynecology, Texas Tech University Health Science Center School of Medicine, Amarillo, Texas, USA.

Müllerian anomalies are usually isolated or found in association with abnormalities of the renal tract. Rarely, they are encountered with coexisting Ggastrointestinal anomalies. Similarly, Hirschsprung's disease may coexist with additional somatic abnormalities, yet only a single case report has reported a müllerian anomaly coexisting with Hirschsprung's. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2017-220246DOI Listing
August 2017
12 Reads

Modified human uterus transplantation using ovarian veins for venous drainage: the first report of surgically successful robotic-assisted uterus procurement and follow-up for 12 months.

Fertil Steril 2017 08;108(2):346-356.e1

Department of Obstetrics and Gynecology, Xijing Hospital, The Fourth Military Medical University, Xi'an, People's Republic of China. Electronic address:

Objective: To report the 12-month results of the first human uterus transplantation case using robot-assisted uterine retrieval. This type of transplantation may become a treatment for permanent uterine factor infertility.

Design: Case study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.fertnstert.2017.05.039DOI Listing
August 2017
56 Reads

Persistent Müllerian duct syndrome: A novel mutation in the Αnti-Müllerian Ηormone gene.

Hormones (Athens) 2017 Apr;16(2):205-208

Medical Genetics Department, Ege University Faculty of Medicine, İzmir, Turkey.

Background And Objective: Persistent Müllerian duct syndrome (PMDS) is a relatively rare form of 46,XY disorder of sex development caused by the failure of formation, release or action of anti-Müllerian hormone (AMH) in intrauterine life. In this report we describe a case diagnosed with PMDS with a novel homozygous mutation in the AMH gene.

Case Report: A 4-month-old male presented with bilateral cryptorchidism and normal external genitalia. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14310/horm.2002.1735DOI Listing
April 2017
43 Reads

Evaluation of Mayer-Rokitansky-Küster-Hauser syndrome with magnetic resonance imaging: Three patterns of uterine remnants and related anatomical features and clinical settings.

Eur Radiol 2017 Dec 3;27(12):5215-5224. Epub 2017 Jul 3.

Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Shuaifuyuan No.1, Wangfujing Street, Dongcheng District, Beijing, 100730, People's Republic of China.

Objective: To characterize the anatomical features and clinical settings of Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome and correlate them with patterns of uterine involvement.

Methods: Pelvic magnetic resonance images and medical records of 92 MRKH patients were retrospectively reviewed. Patients were subgrouped by uterine morphology: uterine agenesis, unilateral rudimentary uterus and bilateral rudimentary uteri. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00330-017-4919-4DOI Listing
December 2017
39 Reads

MR Imaging of Müllerian Fusion Anomalies.

Magn Reson Imaging Clin N Am 2017 Aug 27;25(3):563-575. Epub 2017 May 27.

Department of Radiology and Imaging Sciences, University of Utah, 30 North 1900 East, #1A071, Salt Lake City, UT 84132-2140, USA. Electronic address:

Müllerian duct anomalies, also called congenital uterine anomalies, are developmental structural disorders of the female genital tract. These anomalies are clinically relevant in patients with a history of infertility and pregnancy-related complications. The American Society for Reproductive Medicine classification system is the most well known, although newer systems, such as from the European Society of Human Reproduction and Embryology/European Society for Gynaecological Endoscopy, are becoming more widely accepted. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mric.2017.03.008DOI Listing
August 2017
4 Reads

Quadro-Cornuate Uterus.

J Coll Physicians Surg Pak 2016 Nov;26(11):S97-S99

Department of Gynaecology and Obstetrics, Abbasi Shaheed Hospital and Karachi Medical and Dental College, Karachi.

Congenital malformations of the female genital tract are a group of miscellaneous deviations from normal anatomy with diverse spectrum. Mullerian anomalies are thought to be present in 0.5% of female population. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/212DOI Listing
November 2016
29 Reads