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BMJ Mil Health 2022 Jun 30. Epub 2022 Jun 30.

Trauma & Orthopaedic Surgery, Cardiff and Vale University Health Board, Cardiff, UK.

Haemorrhage from junctional injuries remains the most common cause of battlefield death. Changes to surgical training have meant acquiring and maintaining trauma surgical skills is becoming more difficult for military surgeons. The multidisciplinary Military Operational Specialist Team Training (MOSTT) course is designed to bridge the gap between civilian practice and the deployed environment, as part of predeployment trauma training. Read More

J Anim Sci 2022 Jul;100(7)

Department of Animal and Dairy Sciences, Mississippi State University, Mississippi State, MS 39762, USA.

The human population is ever increasing while the quality and quantity of natural resources used for livestock production decline. This calls for improved product efficiency and the development of improved and sustainable cattle production methods to produce higher quality products to satisfy the demands of both the modern and transient world. The goal of this review was to summarize the interactions, challenges, and opportunities in cattle production relating to their endocrine system, and how reproductive hormones and others impact economically important traits, animal welfare, and human health. Read More

Magn Reson Imaging 2022 Jun 27. Epub 2022 Jun 27.

Department of Biomedical Engineering, University of Alberta, Edmonton, Canada.

Purpose: To optimize quantitative susceptibility-weighted imaging also known as true susceptibility-weighted imaging (tSWI) for strong susceptibility sources like hemorrhage and compare to standard susceptibility-weighted imaging (SWI) and quantitative susceptibility mapping (QSM).

Methods: Ten patients with known intracerebral hemorrhage were scanned using a 3D SWI sequence. The magnitude and phase images were utilized to compute QSM, tSWI and SWI images. Read More

Sci Total Environ 2022 Jun 27:156978. Epub 2022 Jun 27.

Faculty of Humanities and Social Sciences, University of Nottingham Ningbo, Ningbo 315100, China.

Heavy metal pollution control zoning aiming at the health maintenance of watershed soil ecosystem has become an important means of soil environmental protection and governance. Based on the self-organizing map (SOM), this study classifies the data sets of eight heavy metals such as Co, Cd, Zn, Cr, Cu, Pb, Ni, and Tl in 354 samples, calculates the potential ecological risk value of soil heavy metals in combination with the potential Hakansom Risk index (HRI), and uses the geographic information system (GIS) for visualization. In the research results, SOM has divided five soil ecological risk categories. Read More

Int J Law Psychiatry 2022 Jun 27;83:101804. Epub 2022 Jun 27.

Royal Ottawa Health Care Group, Ottawa, ON, Canada; Carleton University, Department of Psychology, Ottawa, ON, Canada. Electronic address:

Three studies examined the psychometric properties of a new scale, the Forensic Stigma Scale (FSS), designed to measure public stigma of forensic patients. In Study 1, the initial item pool was derived to measure three components of stigma (stereotypes, prejudice, discrimination). An EFA (n = 218) identified a two-factor model with 12 items. Read More

Asia Pac J Ophthalmol (Phila) 2022 May 1;11(3):237-246. Epub 2022 May 1.

Singapore National Eye Centre, Singapore Eye Research Institute, Singapore, Singapore.

Abstract: The outbreak of the coronavirus disease 2019 has further increased the urgent need for digital transformation within the health care settings, with the use of artificial intelligence/deep learning, internet of things, telecommunication network/virtual platform, and blockchain. The recent advent of metaverse, an interconnected online universe, with the synergistic combination of augmented, virtual, and mixed reality described several years ago, presents a new era of immersive and real-time experiences to enhance human-to-human social interaction and connection. In health care and ophthalmology, the creation of virtual environment with three-dimensional (3D) space and avatar, could be particularly useful in patient-fronting platforms (eg, telemedicine platforms), operational uses (eg, meeting organization), digital education (eg, simulated medical and surgical education), diagnostics, and therapeutics. Read More

PLoS One 2022 30;17(6):e0270041. Epub 2022 Jun 30.

Explo, academic spinoff, University d'Annunzio of Chieti and Pescara, Pescara, Italy.

The paper uses text mining and semantic algorithms to tag innovative firms and offer an alternative perspective to classify industrial activities. Instead of referring to firms' standard industrial classification codes, we gather information from companies' websites and corporate purposes, extract keywords and generate tags concerning firms' activities, specializations, and competences. Evidence is interesting because allows us to understand 'what firms do' in a more penetrating and updated way than referring to standard industrial classification codes. Read More

PLoS One 2022 30;17(6):e0270194. Epub 2022 Jun 30.

Center for Complex Decision Analysis, Fudan University, Shanghai, China.

Election forecasting has been traditionally dominated by subjective surveys and polls or methods centered upon them. We have developed a novel platform for forecasting elections based on agent-based modeling (ABM), which is entirely independent from surveys and polls. The platform uses statistical results from objective data along with simulation models to capture how voters have voted in past elections and how they are likely to vote in an upcoming election. Read More

Bioinformatics 2022 Jun 30. Epub 2022 Jun 30.

Department of Electronics and Information Engineering, Jeonbuk National University, Jeonju 54896, South Korea.

Motivation: DNA N6-methyladenine (6mA) has been demonstrated to have an essential function in epigenetic modification in eukaryotic species in recent research. 6mA has been linked to various biological processes. It's critical to create a new algorithm that can rapidly and reliably detect 6mA sites in genomes to investigate their biological roles. Read More

Bioinformatics 2022 Jun 30. Epub 2022 Jun 30.

Department of Environmental Medicine, Tianjin Institute of Environmental and Operational Medicine, Tianjin, 300050, China.

Summary: Characterizing biomarkers based on microbiome profiles has great potential for translational medicine and precision medicine. Here, we present microbiomeMarker, an R/Bioconductor package implementing commonly used normalization and differential analysis methods, and three supervised learning models to identify microbiome markers. microbiomeMarker also allows comparison of different methods of differential analysis and confounder analysis. Read More

Bioinformatics 2022 Jun 30. Epub 2022 Jun 30.

Department of Genetics, Albert Einstein College of Medicine, 1300 Morris Park Ave., Bronx, New York, USA.

Summary: The functional sub-string(s) of a biopolymer sequence defines the specificity of its interaction with other biomolecules and is often referred to as motifs. Computational algorithms and software have been broadly developed for finding such motifs in sequences in which the individual elements are single characters, such as those in DNA and protein sequences. However, there are more complex scenarios where the motifs exist in non-single-letter contexts, for example, preferred patterns of chemical modifications on proteins, DNAs, RNAs, or polysaccharides. Read More

Methods Mol Biol 2022 ;2514:45-51

Chemical and Food Engineering Department, Federal University of Santa Catarina, Florianópolis, SC, Brazil.

Spheroids are 3D spherical cell aggregates, which, cultivated in vitro, behave differently than regular monolayer cellular cultures. Cancer spheroids share many characteristics with in vivo solid tumors, making them a powerful tool in cancer research. The use of cancer spheroids makes it possible to identify the potential of new anticancer pharmacological targets, leading them to be widely used in preclinical oncology research. Read More

Environ Sci Pollut Res Int 2022 Jun 30. Epub 2022 Jun 30.

Water Research Center, King Abdulaziz University, P.O. Box 80200, Jeddah, 21598, Saudi Arabia.

Groundwater quality in Yalamlam basin, Saudi Arabia, was appraised for drinking, irrigation, livestock and poultry applications by international standards, drinking water quality index (DWQI), irrigation water quality (IWQ) parameters, and irrigation water quality index (IWQI) calculations. Potential non-carcinogenic health risks due to high NO and F water were assessed for various age groups using the United States Environmental Protection Agency (USEPA) models. Groundwater samples (n = 40) were analyzed for pH, electrical conductivity (EC), and major and minor constituents. Read More

Environ Sci Pollut Res Int 2022 Jun 30. Epub 2022 Jun 30.

College of Environmental Sciences and Engineering, Yangzhou University, Yangzhou, 225217, China.

Although Taihu watershed is an "acid-insensitive" region, anthropogenic acidification has greatly changed the water chemistry in Taihu Lake. However, how soil carbonates responded to the long-term human-induced acidification received less attention. In this work, we investigated soil carbonate concentrations from different land uses in the upstream of the lake and sediment carbonate profiles in the lake, to explore the linkage of carbonates dissolution in the land and sedimentation in the lake. Read More

Microb Genom 2022 Jun;8(6)

UK Health Security Agency, Forvie Site, Addenbrookes' Campus, Robinson Way, Cambridge CB2 0SR, UK.

There is a need to identify microbial sequences that may form part of transmission chains, or that may represent importations across national boundaries, amidst large numbers of SARS-CoV-2 and other bacterial or viral sequences. Reference-based compression is a sequence analysis technique that allows both a compact storage of sequence data and comparisons between sequences. Published implementations of the approach are being challenged by the large sample collections now being generated. Read More

Int J Stroke 2022 Jun 30:17474930221113430. Epub 2022 Jun 30.

National Institute of Stroke and Applied Neurosciences, Auckland University of Technology 93840.

AbstractRationaleTheoretically, most strokes could be prevented through the management of modifiable risk factors. The Stroke Riskometer™ mobile phone application (hereon 'The App') uses an individual's data to provide personalised information and advice to reduce their risk of stroke.AimsTo determine the effect of The App on a combined cardiovascular risk score (Life's Simple 7®, LS7) of modifiable risk factors at 6 months post-randomisation. Read More

Am Surg 2022 Jun 30:31348221109497. Epub 2022 Jun 30.

Department of Surgery, 22494Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Introduction: There is limited data correlating preoperative mobility limitations with clinical outcomes in bariatric patients. This study uses propensity score matching (PSM) to compare 30-day outcomes between patients with preoperative limited mobility (LM) versus patients without (non-LM).

Methods: Using the 2016-2018 Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) database, patients undergoing primary laparoscopic sleeve gastrectomy or gastric bypass were identified. Read More

J Complement Integr Med 2022 Jul 1. Epub 2022 Jul 1.

Centre for Innovations and Technologies (CIT), ADSO Naturals Private Limited, Bangalore, India.

A poorly water soluble polar and non-polar bioactive complexes encapsulated in a nanocellulose-based polymeric network are the focus of this research. Ascorbic acid, resveratrol, holy basil extract, pomegranate extract, and niacin are all microencapsulated bioactive complexes that make up Zetalife, a nutritional ingredient. It uses an interpenetrating polymeric network (IPN) with more dispersed nanocellulose and phospholipids to increase Zetalife s bioavailability. Read More

Biostatistics 2022 Jun 30. Epub 2022 Jun 30.

Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA, USA and Department of Data Science, Dana-Farber Cancer Institute, Boston, MA, USA.

Single-cell RNA sequencing (scRNA-seq) quantifies gene expression for individual cells in a sample, which allows distinct cell-type populations to be identified and characterized. An important step in many scRNA-seq analysis pipelines is the annotation of cells into known cell types. While this can be achieved using experimental techniques, such as fluorescence-activated cell sorting, these approaches are impractical for large numbers of cells. Read More

J Phys Chem Lett 2022 Jun 30:6208-6214. Epub 2022 Jun 30.

School of Chemistry and Chemical Engineering, Guizhou University, No. 2708, South Section of Huaxi Avenue, Guiyang City 550025, Guizhou Province, P. R. China.

The precise self-assembly of DNA molecules can be used to create nanoprecision supramolecular materials. However, the lack of methods to characterize such supramolecular materials limits their development. Surface-enhanced Raman spectroscopy (SERS) is widely used to detect the secondary structure of simple DNA molecules, but its application in the revealing of complex DNA supramolecular information remains challenging. Read More

Am J Chin Med 2022 Jun 30:1-27. Epub 2022 Jun 30.

School of Pharmaceutical Sciences, Health Science Center, Shenzhen University, Shenzhen, P. R. China.

Type 2 diabetes mellitus (T2DM) has become a universal and chronic global public health concern and causes multiple complex complications. In order to meet the rapidly growing demand for T2DM treatment, increased research has been focused on hypoglycemic drugs. (Batal. Read More

Aliment Pharmacol Ther 2022 Jun 30. Epub 2022 Jun 30.

Institute of Liver Studies, King's College Hospital, London, UK.

Background: Chronic hepatitis B remains a global health problem with an estimated 296 million people affected worldwide. Individuals are at risk of serious complications such as cirrhosis and hepatocellular carcinoma and accurately predicting these clinical endpoints has proven difficult. However, several viral biomarkers have recently been developed, including quantitative HBV surface antigen (qHBsAg), hepatitis B RNA (HBV RNA) and core-related antigen (HBcrAg), and shown promise in a range of clinical settings. Read More

Technol Cancer Res Treat 2022 Jan-Dec;21:15330338221108529

37004JCHO Tokyo Shinjuku Medical Center, Tokyo, Japan.

: Hippocampus-sparing whole-brain radiotherapy using Halcyon, an instrument dedicated to volumetric modulated arc therapy, has not been studied till date; hence, we aimed to examine whether it can meet the RTOG0933 criteria. Based on this, we compared Halcyon to Tomotherapy, which also uses an O-ring-type linear accelerator. This exploratory, experimental, and retrospective study used 5 sets of computed tomography images in the head area to investigate the planning target volume, hippocampal doses, and irradiation time. Read More

Front Microbiol 2022 13;13:907631. Epub 2022 Jun 13.

Grupo Inmunomodulación (GIM), Instituto de Investigaciones Médicas, Facultad de Medicina, Corporación Académica para el Estudio de Patologías Tropicales (CAEPT), Universidad de Antioquia, Medellín, Colombia.

A mouse model of cutaneous leishmaniasis (CL) by that reproduces the characteristics of the human disease remains elusive. Here we report the development of a CL model that uses a mouse-adapted isolate to reproducibly induce a dermal disease with a remarkable similarity to human CL. BALB/c mice infected intradermally in the ear with 10 stationary UA-946 promastigotes develop a progressive cutaneous disease that exhibits the typical ulcerated lesions with indurated borders observed in CL patients. Read More

Front Pharmacol 2022 13;13:914951. Epub 2022 Jun 13.

Key Laboratory of Ecology and Environment in Minority Areas (Minzu University of China), National Ethnic Affairs Commission, Beijing, China.

In southwest China, especially in Nujiang, lacquer oil from the drupes of (Stokes) F. A. Barkley, including black lacquer oil (BLO) and white lacquer oil (WLO), is one of the most important edible oils for the local people. Read More

J Appalach Health 2019 27;1(3):6-16. Epub 2019 Sep 27.

University of Kentucky.

Purpose: To help fill this void in the literature, the current study uses a statewide sample to examine how Appalachian DUI offenders differ from non-Appalachian DUI offenders in a predominantly rural state.

Methods: Assessment records for 11,640 Kentucky DUI offenders who completed an intervention in 2017 were examined. Appalachian DUI offenders were compared to non-Appalachian metro and non-metro DUI offenders. Read More

J Environ Public Health 2022 20;2022:6477495. Epub 2022 Jun 20.

School of Humanities, Binzhou Polytechnic, Binzhou 256603, China.

In order to clarify the spatial pattern and influencing factors on industrial agglomeration in urban agglomerations, based on the data of prefecture-level cities from 2006 to 2018, this paper uses spatial standard deviation ellipse to analyze the spatial pattern evolution of manufacturing, producer services, consumer services, and foreign-invested industries and takes a dynamic spatial Durbin model to empirically test the influencing factors of industrial agglomeration in Pearl River Delta (PRD) urban agglomeration. The main conclusions are as follows: 1) the degree of industrial agglomeration is at a low level and the difference in the industrial agglomeration level between cities is mainly manifested in the service industries; 2) manufacturing and foreign-invested industries have entered the stage of industrial diffusion, and all types of industries show an east (by south)-to-west (by north) pattern, with a trend of expansion to the south and north; 3) the agglomeration level of service industries and foreign-invested industries on the east bank of the Pearl River is higher than that on the west; and 4) from the empirical results, there is a general inertia effect in the industrial agglomeration and a siphon effect in the manufacturing agglomeration. Economic scale, transportation infrastructure, government intervention, opening up, and urban environment can all positively influence the agglomeration in some industries, with the apparent spatial spillover effects of each influencing factor. Read More

J Neurol Surg B Skull Base 2022 Jun 9;83(3):312-316. Epub 2021 Mar 9.

Minimally-Invasive Cranial Base and Pituitary Surgery Program, Rose Ella Burkhardt Brain Tumor & Neuro-oncology Center, Cleveland Clinic, Cleveland, Ohio, United States.

 Radiofrequency ablation is widely utilized in otorhinolaryngology. It is used for ablation, coagulation and resection, and hemostasis. It causes tissue destruction through a chemical interaction of ions. Read More

Cureus 2022 May 28;14(5):e25428. Epub 2022 May 28.

Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.

Arterial spin labeling (ASL) is a functional magnetic resonance imaging (fMRI) technique that uses water in arterial blood as a tracer to map an area of interest where the intravascular and extravascular compartments exchange. Our review article focuses primarily on the role of ASL fMRI in assessing perfusion impairment in renal allografts in order to take appropriate steps to eliminate the cause of perfusion impairment at an early stage, thereby extending graft life. The study also highlights various other fMRI techniques that are used to analyze other parameters that affect kidney transplants both acutely and chronically. Read More

SAGE Open Nurs 2022 Jan-Dec;8:23779608221107589. Epub 2022 Jun 23.

College of Nursing, University of Florida, Gainesville, FL. USA.

Introduction: Various domains of psychosocial stress have been significantly related to blood pressure. However, ambiguity is present in how these relationships are defined in the literature.

Objective: To add to the existing literature and examine the relationship between psychosocial stress (financial strain and job strain) and other cofactors on blood pressure. Read More