25,570 results match your criteria Use of Vital Statistics in Obstetrics


Perinatal risk factors for congenital hypothyroidism: A retrospective cohort study performed at a tertiary hospital in China.

Medicine (Baltimore) 2020 Jun;99(26):e20838

Center of Neonatal Screening.

Congenital hypothyroidism (CH) is one of the most common neonatal endocrine diseases. This retrospective cohort study aimed to identify the potential perinatal risk factors for CH and to differentiate between transient and permanent CH (TCH and PCH, respectively) as well as determine their prevalence in a southeastern Chinese population.This study was based on an 18-year surveillance of a neonatal CH screening program in a large tertiary hospital. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000020838DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328952PMC

Atypical polypoid adenomyoma follow-up and management: Systematic review of case reports and series and meta-analysis.

Medicine (Baltimore) 2020 Jun;99(26):e20491

Clinic of Obstetrics and Gynecology, DINOGMI, IRCCS San Martino Hospital, University of Genova, Genova (GE), Italy.

Background: Atypical polypoid adenomyoma (APA) is a rare uterine tumor typically found in fertile age and associated with infertility. Among young nullipara women, conservative treatment is proposed despite the high recurrence rate and the association with endometrial cancer.Our aim was to assess the risk of recurrence with different conservative treatments in fertile ages and the prevalence of malignant or pre-malignant associated lesions to better address an adequate patient counselling when treatment modalities are discussed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000020491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328951PMC

Racial and Ethnic Disparities in Maternal and Neonatal Adverse Outcomes in College-Educated Women.

Obstet Gynecol 2020 Jul;136(1):146-153

Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School, the University of Texas Health Science Center at Houston, Houston, Texas.

Objective: To compare composite maternal and neonatal adverse outcomes among women with at least a bachelor's degree by racial and ethnic groups.

Methods: This was a retrospective cohort study using the U.S. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/AOG.0000000000003887DOI Listing

Maternal Obesity and the Risk of Early-Onset and Late-Onset Hypertensive Disorders of Pregnancy.

Obstet Gynecol 2020 Jul;136(1):118-127

Department of Obstetrics, Gynecology and Reproductive Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas.

Objective: To evaluate the relationship between maternal body mass index (BMI) at delivery and rates of early-onset and late-onset hypertensive disorders of pregnancy.

Methods: We performed a population-based, retrospective cohort study using U.S. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/AOG.0000000000003901DOI Listing

Cytoplasmic versus nuclear THR alpha expression determines survival of ovarian cancer patients.

J Cancer Res Clin Oncol 2020 Aug 12;146(8):1923-1932. Epub 2020 Jun 12.

Department of Pathology, LMU Munich, Thalkirchner Str. 36, 80337, Munich, Germany.

Purpose: Thyroid hormone receptors (THR) have manifold functions and are involved in the carcinogenesis of several tumor types. Within this study, we aimed to investigate the expression pattern (nuclear versus cytoplasmic) of the THR alpha and its impact on patients survival in ovarian cancer (OvCa).

Methods: The presence of the thyroid hormone receptors THRα, THRα1 and - 2 was investigated in 156 ovarian cancer samples using immunohistochemistry (IHC) using semi-quantitative immunoreactivity (IR) scores and correlated with clinical, pathological data, subtype of ovarian cancer, clinical data, staining of 20 already described OvCa marker proteins and overall survival (OS). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00432-020-03241-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324415PMC

The International Network of Obstetric Survey System.

Ceska Gynekol 2020 ;85(2):139-143

Objective: To informed about international surveillance network severe maternal morbidity and mortality - INOSS.

Design: Literature review.

Settings: 1st Department of Gynaecology and Obstetrics Faculty of Medicine, Comenius University and University Hospital, Bratislava, Slovak Republic. Read More

View Article

Download full-text PDF

Source

Association of Cerclage with Composite Adverse Outcomes among Women Delivered at 36 Weeks or Later.

Am J Perinatol 2020 Jun 10. Epub 2020 Jun 10.

Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.

Objective:  This study aimed to compare the maternal and neonatal adverse outcomes among singletons delivered at 36 weeks or later with cerclage during index pregnancy versus those without cerclage.

Study Design:  This retrospective cohort study utilized the U.S. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0040-1712962DOI Listing

Comparisons on perinatal depression between the first-child women and the second-child women in West China under the universal 2-child policy: A STROBE compliant prospective cohort study.

Medicine (Baltimore) 2020 Jun;99(23):e20641

Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University.

Background: Universal 2-child policy was proposed in 2015 in China, but it was still uncertain whether having a second child would have any impacts on maternal health, especially mental health. So, the aim of this study was to compare the incidence of perinatal depression between the first-child women and the second-child women and to describe the patterns of perinatal depression from the first and third trimesters to 6 weeks postpartum.

Methods: A prospective cohort study was conducted in a university hospital, 969 first-child women and 492 second-child women registered in this hospital from Dec 2017 to Mar 2018 were involved in the study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000020641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306296PMC

Role of basic fibroblast growth factor in human immunodeficiency virus associated pre-eclampsia.

J Obstet Gynaecol Res 2020 Jun 5. Epub 2020 Jun 5.

Optics and Imaging Centre, Doris Duke Medical Research Institute, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.

Aim: Cell signaling is vital to ensure successful trophoblast invasion. This study assessed the level of serum basic fibroblast growth factor (FGF-2) in human immunodeficiency virus (HIV) associated pre-eclampsia (PE).

Methods: Using a Bio-plex Multiplex Immunoassay, FGF-2 (pg/mL) was analyzed in blood sera collected from 80 pregnant women attending a large regional hospital in Durban, South Africa. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jog.14335DOI Listing

An experimental and algorithm-based study of the spectral features of breast cancer patients by a photodiagnosis approach.

Photodiagnosis Photodyn Ther 2020 Jun 1:101851. Epub 2020 Jun 1.

Department of Electrical Computer Engineering, COMSATS University Islambad, Islamabad Campus, Park Road, Chak Shahzad, Islamabad, 45550, Pakistan.

In the present study, the spectral diagnosis of blood plasma samples of breast cancer patients and an equal number of normal controls was investigated. A set of ratio parameters was acquired by employing SXS and FES. The samples were also analyzed statistically by employing Welch two-sample t-tests, and the effects of three ratio parameters, R, R, and R, were also studied by plotting them against the subject numbers. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2020.101851DOI Listing

COVID-19 pandemic impact on gynaecological cancers: a perspective.

Authors:
C Uwins G Bhandoria

Br J Surg 2020 Jul 3;107(8):e265. Epub 2020 Jun 3.

Obstetrics and Gynecologic Oncology, Command Hospital, Pune, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/bjs.11728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300774PMC

Surgical Conservative Treatment for Endometrial Cancer in Women of Reproductive Age: Incidence of Urinary Tract Symptoms.

Anticancer Res 2020 Jun;40(6):3065-3069

First Department of Surgery, Laiko General Hospital, National and Kapodistrian University of Athens, Athens, Greece

Endometrial cancer is the most common gynecologic malignancy. The mainstay of treatment for endometrial cancer is total hysterectomy with bilateral salpingo-oophorectomy. Radiation and chemotherapy accompanied with progestins can also play a significant role in treatment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21873/anticanres.14287DOI Listing

Tracheobronchial foreign body aspiration in children: A retrospective single-center cross-sectional study.

Medicine (Baltimore) 2020 May;99(22):e20480

Department of Respiratory Medicine, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai, China.

Foreign body (FB) aspiration is a common and serious problem in childhood as it requires early recognition and treatment to avoid potentially lethal consequences. This study aimed to characterize the clinical and epidemiological features of airway FBs in a pediatric Chinese population.A retrospective review of medical records of children aged 0 to 14 years who attended with a diagnosis of FB aspiration the Shanghai Children's Hospital between January 2013 and December 2017 was carried out. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000020480DOI Listing

Analysis of factors related to fertility after endometriosis combined with infertility laparoscopic surgery.

Medicine (Baltimore) 2020 May;99(21):e20132

Department of Obstetrics and Gynecology, The Affiliated Wuxi Matemity and Child Health Care Hospital of Nanjing Medical University, Wuxi, Jiangsu.

To investigate the influence factors of laparoscopic postoperative pregnancy of patients with endometriosis and infertility, further validate the application of EFI scoring system in endometriosis, and to improve the pregnancy rate.A total of 258 patients with endometriosis and infertility who underwent laparoscopic surgery and follow-up treatment at Wuxi Maternal and Child Health Hospital from January 2015 to December 2016 were selected and divided into pregnant and non-pregnant groups according to whether they were pregnant. All patients were divided into 4 groups according to EFI score: group with EFI score ≥9, 7-8, 4-6, and <4, and divided into I, II, III, and IV groups according to AFS stages. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000020132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249873PMC

Expression of H3K4me3 and H3K9ac in breast cancer.

J Cancer Res Clin Oncol 2020 Aug 28;146(8):2017-2027. Epub 2020 May 28.

Department of Obstetrics and Gynecology, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.

Purpose: Breast cancer is the leading cause of cancer death in females. Histone modifications have been shown to have an influence on the gene expression. This study focusses on the histone modifications H3K9ac and H3K4me3 in breast cancer and their impact on survival METHODS: H3K4me3 and H3K9ac expression was immunohistochemically examined in 235 tissue samples. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00432-020-03265-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324433PMC

Estimation of the time-varying reproduction number of COVID-19 outbreak in China.

Int J Hyg Environ Health 2020 07 11;228:113555. Epub 2020 May 11.

Beijing International Center for Mathematical Research, Peking University, China; Department of Biostatistics, School of Public Health, Peking University, China. Electronic address:

Background: The 2019 novel coronavirus (COVID-19) outbreak in Wuhan, China has attracted world-wide attention. As of March 31, 2020, a total of 82,631 cases of COVID-19 in China were confirmed by the National Health Commission (NHC) of China.

Methods: Three approaches, namely Poisson likelihood-based method (ML), exponential growth rate-based method (EGR) and stochastic Susceptible-Infected-Removed dynamic model-based method (SIR), were implemented to estimate the basic and controlled reproduction numbers. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijheh.2020.113555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211652PMC
July 2020
3.829 Impact Factor

Neonatal Seizures Among Low-Risk Pregnancies at Term: Risk Factors and Adverse Outcomes.

Obstet Gynecol 2020 Jun;135(6):1417-1425

Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School, the University of Texas Health Science Center at Houston, Houston, Texas.

Objective: To examine risk factors and adverse outcomes for neonatal-maternal dyads among low-risk pregnancies at term with subsequent neonatal seizures.

Methods: United States vital statistics data sets were used for this retrospective study. Inclusion criteria were low-risk women (without hypertensive disease or diabetes) with nonanomalous singleton pregnancies, who delivered after labor at 37-41 weeks of gestation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/AOG.0000000000003866DOI Listing

Factors Associated With Maternal and Neonatal Interventions at the Threshold of Viability.

Obstet Gynecol 2020 Jun;135(6):1398-1408

Department of Obstetrics and Gynecology, University of Cincinnati College of Medicine, and the Center for Prevention of Preterm Birth, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

Objective: To quantify the influence of maternal sociodemographic, medical, and pregnancy characteristics on decisions to offer or receive antepartum and neonatal interventions with deliveries occurring at 22-23 weeks of gestation.

Methods: This is a case-control study of U.S. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/AOG.0000000000003875DOI Listing

Maternal prepregnancy BMI and size at birth: race/ethnicity-stratified, within-family associations in over 500,000 siblings.

Ann Epidemiol 2020 Jun 7;46:49-56.e5. Epub 2020 May 7.

Oregon Health & Science University, School of Public Health, Portland, OR; Oregon Health & Science University, Department of Obstetrics and Gynecology, Portland, OR.

Purpose: To estimate racial/ethnic-stratified effects of maternal prepregnancy BMI on size for gestational age at birth, by comparing siblings within families.

Methods: This study examined linked vital statistics and patient discharge data from 580,960 infants born to 278,770 women in the State of California (2007-2012). To control for family-level confounding, we used fixed effects multinomial regression, modeling size for gestational age (small [SGA], appropriate, large [LGA]) as a function of maternal BMI (underweight, normal weight, overweight, obesity class I, II, III) and time-varying covariates. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.annepidem.2020.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315911PMC

Randomized Trial of Lactin-V to Prevent Recurrence of Bacterial Vaginosis.

N Engl J Med 2020 05;382(20):1906-1915

From the Departments of Obstetrics, Gynecology, and Reproductive Sciences (C.R.C., S.N., A.H.) and Laboratory Medicine (L.G., S. Miller), University of California, San Francisco, San Francisco, the Department of Family Medicine, University of California, San Diego, San Diego (S. Morris), and Osel, Mountain View (T.P.) - all in California; Emmes, Rockville, MD (M.R.W., J.P.); the Department of Medicine, Ruth M. Rothstein CORE Center and Stroger Hospital of Cook County Health, Rush University Medical Center, Chicago (A.L.F.); and the Division of Infectious Diseases, Department of Medicine, Washington University, St. Louis (H.R.).

Background: Bacterial vaginosis affects 15 to 50% of women of reproductive age, and recurrence is common after treatment with an antibiotic agent. The high incidence of recurrence suggests the need for new treatments to prevent recurrent bacterial vaginosis.

Methods: We conducted a randomized, double-blind, placebo-controlled, phase 2b trial to evaluate the ability of CTV-05 (Lactin-V) to prevent the recurrence of bacterial vaginosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa1915254DOI Listing

Molecular identification and antifungal susceptibility profile of yeast from vulvovaginal candidiasis.

BMC Infect Dis 2020 Apr 19;20(1):287. Epub 2020 Apr 19.

Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen, 518036, China.

Background: Accurate identification Candida is important for successful therapy and epidemiology study. The aim of research is to study API 20C yeast identification system identification rate by using molecular identification as gold standard and tested the antifungal susceptibility of Candida from patients with vulvovaginal candidiasis (VVC).

Methods: In total, 3574 yeast isolates were obtained from patients with VVC. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12879-020-04985-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216708PMC

Severe maternal morbidity and mortality associated with COVID-19: The risk should not be downplayed.

Acta Obstet Gynecol Scand 2020 07 13;99(7):815-816. Epub 2020 Jun 13.

Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/aogs.13900DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273078PMC

[Observational study of the implementation of medical emergency team in hospital].

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2020 Mar;32(3):362-366

Department of Intensive Care Unit, Fuxing Hospital, Capital Medical University, Beijing 100038, China. Corresponding author: Xi Xiuming, Email:

Objective: To analyze the implementation of medical emergency team (MET) in Fuxing Hospital of Capital Medical University, and to investigate the characteristics such as the time, department, disease, cause of the MET calls, in order to provide a basis for the improvement of MET's implementation.

Methods: A retrospective study was conducted. MET calls that received between January 1st, 2015 and December 31st, 2018 at Fuxing Hospital were collected. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3760/cma.j.cn121430-20200116-00055DOI Listing

A Postpartum Death Due to Coronavirus Disease 2019 (COVID-19) in the United States.

Obstet Gynecol 2020 07;136(1):52-55

Department of Obstetrics and Gynecology, Urban Health Plan, Inc., Bronx, and the Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Weill Cornell Medicine, New York, New York.

Background: Limited U.S. reports of pregnant women with coronavirus disease 2019 (COVID-19) infection describe a few critical cases and no maternal mortality. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/AOG.0000000000003950DOI Listing

Risk Factors for Mortality in 244 Older Adults With COVID-19 in Wuhan, China: A Retrospective Study.

J Am Geriatr Soc 2020 Jun 12;68(6):E19-E23. Epub 2020 May 12.

Department of Infectious Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Background/objectives: Previous studies have reported that older patients may experience worse outcome(s) after infection with severe acute respiratory syndrome coronavirus-2 than younger individuals. This study aimed to identify potential risk factors for mortality in older patients with coronavirus disease 2019 (COVID-19) on admission, which may help identify those with poor prognosis at an early stage.

Design: Retrospective case-control. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jgs.16533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267277PMC

[Effect of exogenous gonadotropin dosage on embryo aneuploidy rate and pregnancy outcome in patients of preimplantation genetic test].

Zhonghua Fu Chan Ke Za Zhi 2020 Apr;55(4):253-258

Department of Obstetrics and Gynecology, The First Medical Center of the PLA General Hospital, Beijing 100853, China.

To investigate the effect of gonadotropin (Gn) on embryo aneuploidy rate and pregnancy outcome during preimplanptation genetic testing for aneuploidy (PGT-A) cycles. The clinical data of patients undergoing PGT-A cycle at the First Medical Center of the PLA General Hospital from January 1, 2013 to May 31, 2019 were retrospectively analyzed. Patients were divided into younger patient group (<35 years old) and elder patient group (≥35 years old) by maternal age, then divided into two groups in line with Gn dosage (≤2 250 U, >2 250 U), and into four groups by number of oocytes retrieved (1-5, 6-10, 11-15 and ≥16 oocytes). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3760/cma.j.cn112141-20200309-00198DOI Listing

Pulmonary embolism in a young pregnant woman with COVID-19.

Thromb Res 2020 07 20;191:36-37. Epub 2020 Apr 20.

Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, A. Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy; Department of Pathophysiology and Transplantation for Health, University of Milan, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.thromres.2020.04.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169886PMC

Exploring the dynamics and interplay of human papillomavirus and cervical tumorigenesis by integrating biological data into a mathematical model.

BMC Bioinformatics 2020 May 5;21(Suppl 7):152. Epub 2020 May 5.

College of Computer Science, Sichuan University, Chengdu, 610065, China.

Background: Cervical cancer is the fourth most common tumor in women worldwide, mostly resulting from high-risk human papillomavirus (HR-HPV) with persistent infection.

Results: The present discoveries are comprised of the following: (i) A total of 16.64% of the individuals were positive for HR-HPV infection, with 13. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12859-020-3454-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199323PMC

Maternal death due to COVID-19.

Am J Obstet Gynecol 2020 07 28;223(1):109.e1-109.e16. Epub 2020 Apr 28.

Division of Maternal-Fetal Medicine, Departments of Obstetrics & Gynecology, Baylor College of Medicine and Texas Children's Hospital, Houston, TX; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX; Department of Molecular and Cell Biology, Baylor College of Medicine, Houston, TX; And the National School of Tropical Medicine, Baylor College of Medicine and Texas Children's Hospital, Houston, TX, Department of Dentistry, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

Background: Despite 2.5 million infections and 169,000 deaths worldwide (as of April 20, 2020), no maternal deaths and only a few pregnant women afflicted with severe respiratory morbidity have been reported to be related to COVID-19 disease. Given the disproportionate burden of severe and fatal respiratory disease previously documented among pregnant women following other coronavirus-related outbreaks (SARS-CoV in 2003 and MERS-CoV in 2012) and influenza pandemics over the last century, the absence of reported maternal morbidity and mortality with COVID-19 disease is unexpected. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajog.2020.04.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187838PMC
July 2020
4.704 Impact Factor

Adverse Outcomes among Low-Risk Pregnancies at 39 to 41 Weeks: Stratified by Birth Weight Percentile.

Am J Perinatol 2020 Apr 27. Epub 2020 Apr 27.

Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.

Objective:  This study aimed to assess the risk of adverse outcomes among low-risk pregnancies at 39 to 41 weeks, stratified by birth weight percentile.

Study Design:  This retrospective cohort study utilized the U.S. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0040-1709673DOI Listing
April 2020
1.597 Impact Factor

Prevalence, antimicrobial susceptibility patterns, serotypes and risk factors for group B streptococcus rectovaginal isolates among pregnant women at Kenyatta National Hospital, Kenya; a cross-sectional study.

BMC Infect Dis 2020 Apr 22;20(1):302. Epub 2020 Apr 22.

Department of Medical Microbiology, University of Nairobi, Nairobi, Kenya.

Background: Estimates of Group B Streptococcus (GBS) disease burden, antimicrobial susceptibility, and serotypes in pregnant women are limited for many resource-limited countries including Kenya. These data are required to inform recommendations for prophylaxis and treatment of infections due to GBS.

Methods: We evaluated the prevalence, antimicrobial susceptibility patterns, serotypes, and risk factors associated with rectovaginal GBS colonization among pregnant women receiving antenatal care at Kenyatta National Hospital (KNH) between August and November 2017. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12879-020-05035-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178604PMC

Burden of HPV related anogenital diseases in young women in Germany - an analysis of German statutory health insurance claims data from 2012 to 2017.

BMC Infect Dis 2020 Apr 22;20(1):297. Epub 2020 Apr 22.

Department of Obstetrics and Gynecology, University Hospital of Duesseldorf, Duesseldorf, Germany.

Background: Most individuals are infected with human papillomavirus (HPV) at least once in their lifetime. Infections with low-risk types can cause genital warts, whereas high-risk types can cause malignant tumors. The aim of this study was to determine the burden of anogenital diseases potentially related to HPV in young women based on German statutory health insurance claims data. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12879-020-05002-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178589PMC

Maternal Mortality in Georgia: Incidence, Causes and Level of Underreporting: A National Reproductive Age Mortality Study 2014.

Int J Womens Health 2020 9;12:277-286. Epub 2020 Apr 9.

Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.

Introduction: Accurate data on maternal mortality are essential for assessing progress towards Sustainable Development Goals (SDG).The aim of the study was to determine the incidence and causes of maternal deaths in Georgia, then explore the potential for improvement of quality of maternal health care. The study's secondary aims were to identify the level of underreporting of maternal deaths in Georgian vital statistics over 1 year (2012) and to compare these results with previous data from 2006. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/IJWH.S227349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154943PMC

High prevalence of spondyloarthritis-like MRI lesions in postpartum women: a prospective analysis in relation to maternal, child and birth characteristics.

Ann Rheum Dis 2020 07 16;79(7):929-934. Epub 2020 Apr 16.

Department of Internal Medicine and Pediatrics, Ghent University Hospital, Ghent, Belgium.

Objectives: Bone marrow oedema (BMO) on MRI of sacroiliac joints (SIJs) represents a hallmark of axial spondyloarthritis (SpA), yet such lesions may also occur under augmented mechanical stress in healthy subjects. We therefore sought to delineate the relationship between pregnancy/delivery and pelvic stress through a prospective study with repeated MRI. Results were matched with maternal, child and birth characteristics. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/annrheumdis-2020-217095DOI Listing

Association between apgar score at 5 minutes and adverse outcomes among Low-Risk pregnancies.

J Matern Fetal Neonatal Med 2020 Apr 16:1-8. Epub 2020 Apr 16.

Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.

Among low-risk pregnancies, we aimed to ascertain the association between 5-minute Apgar score and adverse outcomes of newborn-maternal dyad. We conducted a retrospective cohort study using the U.S. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14767058.2020.1754789DOI Listing

The impact of assisted reproductive technology on prenatally diagnosed fetal growth restriction in dichorionic twin pregnancies.

PLoS One 2020 16;15(4):e0231028. Epub 2020 Apr 16.

Department of Health Sciences, University of Florence, Florence, Italy.

Objective: Whether the use of assisted reproductive technologies (ART) affects the outcome of twin pregnancies is still a matter of debate. Previous studies have evaluated the association between birth weight and ART, without a clear distinction between fetal growth restriction (FGR), a condition at higher risk of adverse outcome, and constitutionally small for gestational age (SGA) fetuses. The aim of this study was to determine whether dichorionic (DC) twin pregnancies obtained by ART have a greater risk of developing FGR, defined by accurate ultrasound criteria, than those spontaneously conceived (SC), and to compare the severity of ultrasound features in the growth restricted fetuses. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0231028PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162456PMC

Use of electronic medical records in development and validation of risk prediction models of hospital readmission: systematic review.

BMJ 2020 04 8;369:m958. Epub 2020 Apr 8.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.

Objective: To provide focused evaluation of predictive modeling of electronic medical record (EMR) data to predict 30 day hospital readmission.

Design: Systematic review.

Data Source: Ovid Medline, Ovid Embase, CINAHL, Web of Science, and Scopus from January 2015 to January 2019. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmj.m958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249246PMC

Clinical Characteristics of COVID-19 After Gynecologic Oncology Surgery in Three Women: A Retrospective Review of Medical Records.

Oncologist 2020 06 7;25(6):e982-e985. Epub 2020 Apr 7.

Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People's Republic of China.

From a large medical center in Wuhan, the epicenter of the 2019 novel coronavirus disease (COVID-19), we report clinical features and prognosis for three women diagnosed with COVID-19 after gynecologic oncology surgery and hospitalized in January 2020. The incidence of COVID-19 was 0.77% (3 of 389) of total hospitalizations and 1. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1634/theoncologist.2020-0157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262154PMC
June 2020
4.865 Impact Factor

Maternal and perinatal outcomes with COVID-19: A systematic review of 108 pregnancies.

Acta Obstet Gynecol Scand 2020 07 20;99(7):823-829. Epub 2020 Apr 20.

Department of Clinical Sciences Lund, Pediatrics/Neonatology, Lund University, Malmö/Lund, Sweden.

Introduction: The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has exposed vulnerable populations to an unprecedented global health crisis. The knowledge gained from previous human coronavirus outbreaks suggests that pregnant women and their fetuses are particularly susceptible to poor outcomes. The objective of this study was to summarize the clinical manifestations and maternal and perinatal outcomes of COVID-19 during pregnancy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/aogs.13867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262097PMC

Challenges to improve antenatal and intrapartum care in South Africa.

S Afr Med J 2019 Dec 5;109(11b):15-19. Epub 2019 Dec 5.

Department of Obstetrics and Gynaecology, School of Medicine, Faculty of Health Sciences, and Research Centre for Maternal, Fetal, Newborn and Child Health Care Strategies, University of Pretoria, and Maternal and Infant Health Care Strategies Research Unit, South African Medical Research Council, Pretoria, South Africa.

The major causes of maternal and perinatal deaths have been well described in South Africa. These causes are related to HIV infection, placental insufficiency and intrapartum asphyxia. The health system failures that most commonly lead to preventable mortality are related to managing hypertensive disorders in pregnancy (HDP), detecting fetal growth restriction antenatally and managing labour effectively by providing caesarean delivery to those who need it and avoiding it in those who do not. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7196/SAMJ.2019.v109i11b.14248DOI Listing
December 2019

Prognostic significance of lymphocyte monocyte ratio in patients with ovarian cancer.

Medicine (Baltimore) 2020 Apr;99(14):e19638

Department of Gynecology and Obstetrics, Key Laboratory of Obstetrics & Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, West China Second Hospital, Sichuan University.

Background: This study aimed to systematically assess the prognostic value of lymphocyte monocyte ratio (LMR) in patients with ovarian cancer through performing a meta-analysis.

Methods: Web of Science, PubMed, EMBASE, Cochrane Library, and China National Knowledge Infrastructure databases were searched for potentially eligible studies. The baseline characteristics and relevant data were extracted. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000019638DOI Listing

Motivation to access laparoscopic skills training: Results of a Canadian survey of obstetrics and gynecology residents.

PLoS One 2020 2;15(4):e0230931. Epub 2020 Apr 2.

Division of Gynecologic-Oncology, Dalhousie University, Halifax, Nova Scotia, Canada.

Objective: Competency based medical education (CBME) requires novel approaches to surgical education. Significant investment has been made in laparoscopic simulation, which has been shown to foster skill development prior to patient encounters. However, research suggests variable voluntary use of these resources by residents, and little is known about the motivational factors that influence their utilization. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0230931PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117757PMC

Prevalence and knowledge of heavy menstrual bleeding among gynecology outpatients by scanning a WeChat QR Code.

PLoS One 2020 2;15(4):e0229123. Epub 2020 Apr 2.

Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijing, China.

The aim of this study was to assess menstrual blood loss (MBL) and knowledge of heavy menstrual bleeding (HMB) among the gynecology outpatients at Peking University People's Hospital, by scanning a WeChat (a social media application software developed by Tencent) QR Code using a mobile phone or tablet. This survey was conducted among outpatients who were treated at the Gynecology Department of Peking University People's Hospital between September 2016 and November 2016. All participants filled up the questionnaires and scales through WeChat: general information questionnaire, Pictorial Blood Loss Assessment Chart (PBAC), Menorrhagia Multi-Attribute Quality-of-Life Scale (MMAS), and HMB knowledge questionnaire. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0229123PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117654PMC
July 2020
3.234 Impact Factor

Vertical Transmission of Coronavirus Disease 19 (COVID-19) from Infected Pregnant Mothers to Neonates: A Review.

Fetal Pediatr Pathol 2020 Jun 2;39(3):246-250. Epub 2020 Apr 2.

Neonatal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Since early December 2019, the Coronavirus Disease 19 (COVID-19) infection has been prevalent in China and eventually spread to other countries. There are a few published cases of COVID-19 occurring during pregnancy and due the possibility of mother-fetal vertical transmission, there is a concern that the fetuses may be at risk of congenital COVID-19. We reviewed the risk of vertical transmission of COVID-19 to the fetus of infected mothers by using data of published articles or official websites up to March 4, 2020. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15513815.2020.1747120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157948PMC
June 2020
0.398 Impact Factor

Assessment of Serological Markers of Genital Chlamydia trachomatis Infection Among the Gynaecology Patients attending Babcock University Teaching Hospital, Ilishan-Remo, Ogun State, Nigeria.

Afr J Reprod Health 2019 Dec;23(4):54-62

Department of Medical Microbiology, Babcock University Teaching Hospital, Ilishan-Remo, Ogun State, Nigeria.

Genital Chlamydia trachomatis infection causes significant morbidity and mortality in women. A number of epidemiologic studies have suggested that Polymerase Chain Reaction (PCR) is more accurate as a diagnostic tool for Chlamydia trachomatis. However, the use of serological markers may be cost effective and practical in diagnosing and estimating the burden of the disease in resource limited countries. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.29063/ajrh2019/v23i4.7DOI Listing
December 2019

Pregnancy, time to pregnancy and obstetric outcomes among female childhood cancer survivors: results of the DCOG LATER-VEVO study.

J Cancer Res Clin Oncol 2020 Jun 27;146(6):1451-1462. Epub 2020 Mar 27.

Department of Paediatric Oncology, Emma Children's Hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands.

Purpose: To evaluate pregnancy rates, time to pregnancy (TTP) and obstetric outcomes in female childhood cancer survivors (CCSs) and to identify specific diagnosis- and treatment-related factors associated with these outcomes.

Methods: The study is part of the DCOG LATER-VEVO study, a nationwide multicenter cohort study evaluating fertility among long-term Dutch female CCSs. Data were collected by questionnaire. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00432-020-03193-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230041PMC

Endovascular coiling versus surgical clipping for the treatment of unruptured cerebral aneurysms: Direct comparison of procedure-related complications.

Medicine (Baltimore) 2020 Mar;99(13):e19654

Department of Neurosurgery, Liaocheng People's Hospital, Liaocheng, Shandong.

Background: Endovascular coiling and surgical clipping are routinely used to treat unruptured cerebral aneurysms (UCAs). However, the evidence to support the efficacy of these approaches is limited. We aimed to analyze the efficacy of endovascular coiling compared with surgical clipping in patients with UCAs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000019654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220217PMC

Incidence, Origin, and Predictive Model for the Detection and Clinical Management of Segmental Aneuploidies in Human Embryos.

Am J Hum Genet 2020 04 26;106(4):525-534. Epub 2020 Mar 26.

Igenomix Italy, 36063, Marostica, Italy; DAHFMO, Unit of Histology and Medical Embryology, Sapienza, University of Rome, 00161, Roma, Italy; Igenomix Foundation, 46980, Valencia, Spain. Electronic address:

Despite next-generation sequencing, which now allows for the accurate detection of segmental aneuploidies from in vitro fertilization embryo biopsies, the origin and characteristics of these aneuploidies are still relatively unknown. Using a multifocal biopsy approach (four trophectoderms [TEs] and one inner cell mass [ICM] analyzed per blastocyst; n = 390), we determine the origin of the aneuploidy and the diagnostic predictive value of segmental aneuploidy detection in TE biopsies toward the ICM's chromosomal constitution. Contrary to the prevalent meiotic origin of whole-chromosome aneuploidies, we show that sub-chromosomal abnormalities in human blastocysts arise from mitotic errors in around 70% of cases. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajhg.2020.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118577PMC
April 2020
10.931 Impact Factor

Endometriosis.

N Engl J Med 2020 03;382(13):1244-1256

From the Endometriosis Care and Research (CaRe) Centre, Nuffield Department of Women's and Reproductive Health (K.T.Z., C.M.B.), and Wellcome Centre for Human Genetics (K.T.Z.), University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom; the Division of Adolescent and Young Adult Medicine, Department of Medicine, Boston Children's Hospital and Harvard Medical School, Boston Center for Endometriosis, Boston Children's Hospital and Brigham and Women's Hospital, and the Department of Epidemiology, Harvard T.H. Chan School of Public Health - all in Boston (S.A.M.); and the Department of Obstetrics, Gynecology, and Reproductive Biology, College of Human Medicine, Michigan State University, Grand Rapids (S.A.M.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMra1810764DOI Listing