23,168 results match your criteria Use of Vital Statistics in Obstetrics


Predictive value of a modified classification of fallopian tube status on prognosis of tubal factor infertility after laparoscopic surgery.

Medicine (Baltimore) 2019 Mar;98(13):e14952

Department of Obstetrics and Gynecology, Fujian Provincial Maternity and Children's Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian.

Built on 2 existing classification systems, this study was to develop a new classification system to better predict the pregnancy prognosis after laparoscopic surgery in patients with tubal factor infertility and accordingly propose a management strategy.We followed up 423 patients suffering from tubal factor infertility who had undergone hysteroscopic-laparoscopic surgery for 2 years without in vitro fertilization and embryo transfer (IVF/ET). Based on the operative reports, a new, modified classification of fallopian tube status (hereafter referred to as the modified classification) was developed with reference to the 2 existing classification systems (the r-AFS classification of pelvic adhesions and the scoring system of distal tubal obstruction). Read More

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http://dx.doi.org/10.1097/MD.0000000000014952DOI Listing
March 2019
4 Reads

Exorcizing Yerushalmy's ghost.

Authors:
K S Joseph

Paediatr Perinat Epidemiol 2019 03;33(2):116-118

Department of Obstetrics and Gynaecology, and the School of Population and Public Health, University of British Columbia and the Children's and Women's Hospital and Health Centre of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1111/ppe.12547DOI Listing
March 2019
1 Read

There are racial and ethnic disparities in infertility, indeed, but we need better data.

Authors:
Courtney D Lynch

Paediatr Perinat Epidemiol 2019 03;33(2):126-128

Department of Obstetrics and Gynecology, The Ohio State University College of Medicine, Columbus, Ohio.

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http://dx.doi.org/10.1111/ppe.12548DOI Listing
March 2019
1 Read

Association Between Year of Birth and 1-Year Survival Among Extremely Preterm Infants in Sweden During 2004-2007 and 2014-2016.

JAMA 2019 03;321(12):1188-1199

Swedish Neonatal Quality Register, Umeå University Hospital, Umeå, Sweden.

Importance: Since 2004-2007, national guidelines and recommendations have been developed for the management of extremely preterm births in Sweden. If and how more uniform management has affected infant survival is unknown.

Objective: To compare survival of extremely preterm infants born during 2004-2007 with survival of infants born during 2014-2016. Read More

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http://dx.doi.org/10.1001/jama.2019.2021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439685PMC
March 2019
2 Reads
35.289 Impact Factor

Effect of Sustained Inflations vs Intermittent Positive Pressure Ventilation on Bronchopulmonary Dysplasia or Death Among Extremely Preterm Infants: The SAIL Randomized Clinical Trial.

JAMA 2019 03;321(12):1165-1175

Department of Pediatrics, Saitama Medical Center, Saitama Medical University, Kawagoe, Saitama, Japan.

Importance: Preterm infants must establish regular respirations at delivery. Sustained inflations may establish lung volume faster than short inflations.

Objective: To determine whether a ventilation strategy including sustained inflations, compared with standard intermittent positive pressure ventilation, reduces bronchopulmonary dysplasia (BPD) or death at 36 weeks' postmenstrual age without harm in extremely preterm infants. Read More

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http://jama.jamanetwork.com/article.aspx?doi=10.1001/jama.20
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http://dx.doi.org/10.1001/jama.2019.1660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439695PMC
March 2019
21 Reads
35.289 Impact Factor

Primary peritoneal carcinosarcoma: A report of two cases.

Taiwan J Obstet Gynecol 2019 Mar;58(2):288-291

Department of Obstetrics and Gynecology, Taipei Medical University Hospital, Taipei, Taiwan. Electronic address:

Objective: Carcinosarcomas also known as malignant mixed mullerian tumors (MMMTs) contain both carcinomatous and sarcomatous elements. Most MMMTs are arising from female genital tract, including ovaries, uterus and fallopian tubes. Extragenital carcinosarcomas are extremely rare, with an estimation less than 40 cases so far. Read More

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http://dx.doi.org/10.1016/j.tjog.2018.12.001DOI Listing
March 2019
1 Read

Performance of preimplantation genetic testing for aneuploidy in IVF cycles for patients with advanced maternal age, repeat implantation failure, and idiopathic recurrent miscarriage.

Taiwan J Obstet Gynecol 2019 Mar;58(2):239-243

Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan; Department of Obstetrics and Gynecology, Chung Shan Medical University Hospital, Taichung, Taiwan; Lee Womens' Hospital, Taichung, Taiwan.

Objective: The primary objective of this study was to investigate whether preimplantation genetic testing for aneuploidy (PGT-A) of blastocysts through array comparative genomic hybridization (aCGH) improves live birth rates (LBR) in IVF cycles for patients with high prevalence of aneuploidy.

Materials And Methods: This study included 1389 blastocysts with aCGH results derived from 296 PGT-A cycles in IVF patients with advanced maternal age (AMA) (n = 87, group A), those with repeated implantation failure (RIF) (n = 82, group B), those with recurrent miscarriage (RM) (n = 82, group C), and oocyte donors (OD) (n = 45, young age, as a control group). Another 61 AMA patients without PGT-A procedures were used as a control group for group A. Read More

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http://dx.doi.org/10.1016/j.tjog.2019.01.013DOI Listing
March 2019
3 Reads

Analysis of 62 placental abruption cases: Risk factors and clinical outcomes.

Taiwan J Obstet Gynecol 2019 Mar;58(2):223-226

Department of Obstetrics and Gynecology, The Second Hospital of Jilin University, Changchun 130041, China. Electronic address:

Objective: This study aimed to explore the clinical characteristics and outcomes of placental abruption.

Materials And Methods: A total of 62 placental abruption cases were collected from the Second Hospital of Jilin University between January 2007 and December 2012. A retrospective study was conducted to explore the risk factors for placental abruption, clinical characteristics, and maternal and fetal outcomes. Read More

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http://dx.doi.org/10.1016/j.tjog.2019.01.010DOI Listing
March 2019
1 Read
1.261 Impact Factor

Predictive factors of severe perioperative morbidity of radical hysterectomy with lymphadenectomy in early-stage cervical cancer: A French prospective multicentric cohort of 248 patients.

Eur J Surg Oncol 2019 04 17;45(4):650-658. Epub 2018 Oct 17.

Gynecologic and Breast Oncologic Surgery Department, Georges Pompidou European, Hospital, Paris, France; Paris Descartes University, Sorbonne Paris Cité, Faculty of Medicine, Paris, France.

Objective: The purpose of this study was to assess the postoperative morbidity after radical hysterectomy (RH) for early-stage cervical cancer and to determine risk factors of severe perioperative morbidity.

Methods: Data of two prospective trials on sentinel node biopsy for cervical cancer (SENTICOL I & II) were analysed. Patients having a radical hysterectomy were included between 2005 and 2012 from 25 French oncologic centers. Read More

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http://dx.doi.org/10.1016/j.ejso.2018.10.057DOI Listing
April 2019
2 Reads

[A single-center study of the incidence of neonatal birth trauma and its risk factors].

Zhongguo Dang Dai Er Ke Za Zhi 2019 Mar;21(3):249-252

Department of Pediatrics, Peking University International Hospital, Beijing 102206, China.

Objective: To investigate the incidence of neonatal birth trauma in the department of obstetrics in a single-center medical institution and the risk factors for neonatal birth trauma.

Methods: The maternal and infant medical records of all full-term singleton neonates delivered in the Department of Obstetrics, Peking University International Hospital, from October 2015 to September 2018 were collected. The neonates with birth trauma were assigned to case group, and those without birth trauma were assigned to control group. Read More

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March 2019
7 Reads

[An epidemiologic study of pelvic organ prolapse in urban Chinese women: a population-based sample in China].

Zhonghua Yi Xue Za Zhi 2019 Mar;99(11):857-861

Department of Gynecology and Obstetrics, Peking Union Medical College Hospital, Peking Union Medical College, Beijing 100730, China.

This study aimed to assess the prevalence and factors associated with pelvic organ prolapse (POP) in a representative sample of Chinese urban women. A total of 29613 Chinese urban women were recruited to this cross-sectional study between February 2014 and March 2016. The prevalence of POP, defined as any stage Ⅱ or higher POP resulting in symptoms, was assessed using questionnaires and physical examinations. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.11.012DOI Listing
March 2019
1 Read

[Analysis of screening strategy of group B streptococcus in the third trimester and its influence on pregnancy outcome].

Zhonghua Fu Chan Ke Za Zhi 2019 Mar;54(3):154-159

Department of Obstetrics and Gynecology, Bao'an Maternal and Child Health Hospital, Jinan University, Shenzhen 518106, China.

To investigate the screening strategy of group B streptococcus (GBS) in the reproductive tract of women in the third trimester and analyze its impact on pregnancy outcome. A total of 85 461 pregnant women in 35-37 weeks of gestation from Bao'an Maternity and Child Health Hospital, Jinan University from January 2011 to June 2018 were enrolled. They were divided into 3 periods according to different GBS screening strategies, the unscreened period included 31 384 cases (36. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-567x.2019.03.003DOI Listing
March 2019
3 Reads

Trend and survival outcome in Taiwan cervical cancer patients: A population-based study.

Medicine (Baltimore) 2019 Mar;98(11):e14848

Department of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.

Cervical cancer is one of the most common cancers in Taiwan. The aim of this study was to estimate the incidence of cervical cancer in Taiwan, the relationship between cervical cancer and previous co-morbidities, and the long-term trend of cervical cancer mortality differences in the rest of the world.This study was based on the data of cervical cancer in the National Health Insurance Research Database from 1997 to 2013, and estimated the annual prevalence and incidence of cervical cancer. Read More

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http://dx.doi.org/10.1097/MD.0000000000014848DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426611PMC
March 2019
1 Read

Neonatal and Maternal Morbidity Among Low-Risk Nulliparous Women at 39-41 Weeks of Gestation.

Obstet Gynecol 2019 Apr;133(4):729-737

Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School, the University of Texas Health Science Center at Houston, Houston, Texas; and the Department of Obstetrics and Gynecology, Northwestern University, Chicago, Illinois.

Objective: To use a large national database to compare composite maternal or neonatal morbidity among low-risk, full-term women.

Methods: This cohort study, using the U.S. Read More

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http://dx.doi.org/10.1097/AOG.0000000000003064DOI Listing
April 2019
3 Reads

Change in Second-Trimester Abortion After Implementation of a Restrictive State Law.

Obstet Gynecol 2019 Apr;133(4):771-779

Department of Health Care Organization and Policy, University of Alabama at Birmingham, Birmingham, Alabama; Ibis Reproductive Health, Oakland, California; Population Research Center, University of Texas at Austin, Austin, Texas; and Advancing New Standards in Reproductive Health (ANSIRH), Bixby Center for Global Reproductive Health, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, California.

Objective: To assess whether indicators of limited access to services explained changes in rates of second-trimester abortion after implementation of a restrictive abortion law in Texas.

Methods: We used cross-sectional vital statistics data on abortions performed in Texas before (November 1, 2011-October 31, 2012) and after (November 1, 2013-October 31, 2014) implementation of Texas' abortion law. We conducted monthly mystery client calls for information about abortion facility closures and appointment wait times to calculate distance from women's county of residence to the nearest open Texas facility, the number of open abortion facilities in women's region of residence (facility network size), and days until the next consultation visit. Read More

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http://dx.doi.org/10.1097/AOG.0000000000003183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435408PMC

Antioxidants for male subfertility.

Cochrane Database Syst Rev 2019 03 14;3:CD007411. Epub 2019 Mar 14.

Department of Gynaecology and Obstetrics, Radboud University Medical Center, Nijmegen, Netherlands.

Background: The inability to have children affects 10% to 15% of couples worldwide. A male factor is estimated to account for up to half of the infertility cases with between 25% to 87% of male subfertility considered to be due to the effect of oxidative stress. Oral supplementation with antioxidants is thought to improve sperm quality by reducing oxidative damage. Read More

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http://doi.wiley.com/10.1002/14651858.CD007411.pub4
Publisher Site
http://dx.doi.org/10.1002/14651858.CD007411.pub4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416049PMC
March 2019
12 Reads

Prospective observational cohort study: Computational models for early prediction of ongoing pregnancy in fresh IVF/ICSI-ET protocols.

Life Sci 2019 Apr 8;222:221-227. Epub 2019 Mar 8.

Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China; Key Laboratory of Assisted Reproduction (Peking University), Ministry of Education, Beijing 100191, China; National Clinical Research Center for Obstetrics and Gynecology, Beijing 100191, China; Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology, Beijing 100191, China.

Purpose: This study sought to identify the significant factors related to ongoing pregnancy (OP) and to discover the most reliable model to distinguish OP from non-OP in early gestational age.

Methods: A total of 1650 cycles were enrolled in this study. Univariate Logistic Regression was used to identify the predictors included in multivariable analysis. Read More

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http://dx.doi.org/10.1016/j.lfs.2019.03.012DOI Listing
April 2019
1 Read

Frequency and risk factors for arm lymphedema after multimodal breast-conserving treatment of nodal positive breast Cancer - a long-term observation.

Radiat Oncol 2019 Mar 7;14(1):39. Epub 2019 Mar 7.

Department of Radiation Oncology, Hannover Medical School (MHH), Carl-Neuberg-Straße 1, 30625, Hannover, Germany.

Background: Arm-lymphedema is a major complication after breast cancer. Recent studies demonstrate the validity of predicting Breast Cancer Related Lymphedema (BCRL) by self-reports. We aimed to investigate the rate of BCRL and its risk factors in the long-term using self-reported symptoms. Read More

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https://ro-journal.biomedcentral.com/articles/10.1186/s13014
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http://dx.doi.org/10.1186/s13014-019-1243-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407279PMC
March 2019
6 Reads

Are interventions in reproductive medicine assessed for plausible and clinically relevant effects? A systematic review of power and precision in trials and meta-analyses.

Hum Reprod 2019 Apr;34(4):659-665

Centre for Biostatistics, Division of Population Health, Health Services Research and Primary Care, University of Manchester, Manchester, UK.

Study Question: How much statistical power do randomised controlled trials (RCTs) and meta-analyses have to investigate the effectiveness of interventions in reproductive medicine?

Summary Answer: The largest trials in reproductive medicine are unlikely to detect plausible improvements in live birth rate (LBR), and meta-analyses do not make up for this shortcoming.

What Is Known Already: Effectiveness of interventions is best evaluated using RCTs. In order to be informative, these trials should be designed to have sufficient power to detect the smallest clinically relevant effect. Read More

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http://dx.doi.org/10.1093/humrep/dez017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443111PMC

Adjuvant gonadotropin-releasing hormone analogues for the prevention of chemotherapy-induced premature ovarian failure in premenopausal women.

Cochrane Database Syst Rev 2019 03 3;3:CD008018. Epub 2019 Mar 3.

Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, No. 17, Section Three, Ren Min Nan Lu Avenue, Chengdu, Sichuan, China, 610041.

Background: This is an update of the original review published in the Cochrane Database of Systematic Reviews 2011, Issue 11, and updated in 2015, Issue 4.Chemotherapy has significantly improved prognosis for women with malignant and some non-malignant conditions. This treatment, however, is associated with ovarian toxicity. Read More

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http://dx.doi.org/10.1002/14651858.CD008018.pub3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397718PMC
March 2019
1 Read

Recurrence risk of preeclampsia in a linked population-based cohort: Effects of first pregnancy maximum diastolic blood pressure and gestational age.

Pregnancy Hypertens 2019 Jan 2;15:32-36. Epub 2018 Nov 2.

Department of Epidemiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, the Netherlands. Electronic address:

Objective: To estimate preeclampsia occurrence and recurrence risk in the 2nd pregnancy and analyze associated risk factors such as 1st pregnancy maximum diastolic blood pressure (maxDBP) and gestational age at delivery (GA).

Study Design: Linked cohort of 1st and 2nd pregnancies of 272,551 women from the Dutch Perinatal Registry collected between 2000 and 2007. We defined preeclampsia as hypertension (maxDBP ≥90 mmHg or documented hypertension) plus proteinuria (≥300 mg/24 h) and analyzed its 2nd pregnancy occurrence with logistic regression. Read More

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http://dx.doi.org/10.1016/j.preghy.2018.10.010DOI Listing
January 2019
2 Reads

Telehealth with remote blood pressure monitoring for postpartum hypertension: A prospective single-cohort feasibility study.

Pregnancy Hypertens 2019 Jan 31;15:171-176. Epub 2018 Dec 31.

Division of Cardiovascular Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, WI, United States.

Objective: Investigate feasibility of telehealth with remote blood pressure monitoring for management of hypertension in postpartum women at risk of severe hypertension after hospital discharge.

Methods: In a single-center, prospective single-cohort feasibility study, women with hypertension in pregnancy participated in a postpartum telehealth intervention for blood pressure management after discharge. The primary feasibility outcome measures were recruitment and retention through 6 weeks postpartum. Read More

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http://dx.doi.org/10.1016/j.preghy.2018.12.007DOI Listing
January 2019
1 Read

Risk of hypertension and abnormal biomarkers in the first year postpartum associated with hypertensive disorders of pregnancy among overweight and obese women.

Pregnancy Hypertens 2019 Jan 2;15:1-6. Epub 2018 Nov 2.

Department of Obstetrics, Gynecology and Reproductive Sciences, Univeristy of Pittsburgh School of Medicine, United States; Magee-Womens Research Institute, University of Pittsburgh, United States; Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, United States.

Objectives: Hypertension and obesity are common cardiometabolic risk factors in reproductive age women. The association of hypertensive disorders of pregnancy with later-life cardiovascular disease is well-established, however, it is unknown how obesity and hypertensive disorders of pregnancy converge to accelerate development of hypertension in the postpartum period. The aim of this study was to characterize rates of sustained hypertension at one year postpartum using the new American Heart Association/American College of Cardiology Guidelines among overweight and obese women with a normotensive pregnancy or hypertensive disorder of pregnancy. Read More

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http://dx.doi.org/10.1016/j.preghy.2018.10.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400304PMC
January 2019
1 Read

Disparate Rates of Cesarean Delivery in Term Nulliparous Women with Hypertensive Disorders of Pregnancy.

Am J Perinatol 2019 Mar 1. Epub 2019 Mar 1.

Department of Obstetrics and Gynecology, University of California, Irvine Medical Center, Orange, California.

Objective:  To evaluate the prevalence of cesarean delivery in women with hypertensive disorders of pregnancy (HDP), and explore whether maternal, sociodemographic, or obstetric comorbidities contribute to cesarean delivery rates.

Study Design:  This is a retrospective cohort study of nulliparous, term, singleton, vertex women using the 2013 U.S. Read More

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http://dx.doi.org/10.1055/s-0039-1681057DOI Listing
March 2019
2 Reads

Maternal death reviews: A retrospective case series of 90 hospital-based maternal deaths in 11 hospitals in Indonesia.

Int J Gynaecol Obstet 2019 Feb;144 Suppl 1:59-64

Pfizer Inc, New York, NY, USA.

Objective: To determine the factors contributing to hospital-based maternal deaths in Indonesia, given most women deliver with skilled birth attendants and in health facilities.

Methods: A retrospective review of case records examined quality of care issues related to maternal mortality in hospital settings. The review abstracted information from blinded medical records of 90 women who died in 11 hospitals from January to June 2014. Read More

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http://dx.doi.org/10.1002/ijgo.12736DOI Listing
February 2019
1 Read

Presence of doctors and obstetrician/gynecologists for patients with maternal complications in hospitals in six provinces of Indonesia.

Int J Gynaecol Obstet 2019 Feb;144 Suppl 1:42-50

Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.

Objective: To describe doctors' and specialist physicians' availability to manage obstetric complications in hospitals in six provinces of Indonesia.

Methods: Data from a nonrandomized, quasi-experimental pre-post evaluation study were used to describe the distribution of providers by each cadre of worker and assess the availability of doctors and obstetrician/gynecologists (ob/gyns) for consultations for women experiencing postpartum hemorrhage or pre-eclampsia/eclampsia, disaggregated by hospital type, province, referral status, and by time of day of provider consultation.

Results: Among hospitals that should have comprehensive emergency obstetric and newborn care (CEmONC) services available 24 hours a day, 7 days a week, many did not have a doctor available to manage obstetric complications as they presented, despite there being an average of seven ob/gyns and four doctors registered for service across all facilities. Read More

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http://dx.doi.org/10.1002/ijgo.12734DOI Listing
February 2019
2 Reads

A Randomized Trial of Lymphadenectomy in Patients with Advanced Ovarian Neoplasms.

N Engl J Med 2019 02;380(9):822-832

From the Department of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte, Essen (P. Harter, A. du Bois), Department of Gynecology, Charité-Universitätsmedizin Berlin, Berlin (J.S.), the Coordinating Center for Clinical Trials, Philipps University Marburg (A.R., C.S.-B.), and the Department of Gynecology and Obstetrics, University Hospital Giessen and Marburg (U.W.), Marburg, the Department of Gynecology and Obstetrics, Kaiserswerther Diakonie (B.L.), and the Department of Obstetrics and Gynecology, Heinrich-Heine-University Düsseldorf (W.M.), Düsseldorf, the Department of Gynecology and Obstetrics, University Medicine Greifswald, Greifswald (A.M.), the Department of Gynecology, University Medical Center Hamburg-Eppendorf (S.M.), and the Department of Gynecology and Obstetrics, Albertinen Krankenhaus (I.L.), Hamburg, University Women's Hospital, Department of Gynecology and Reproductive Medicine and Center for Gynecologic Oncology, Jena University Hospital, Jena (I.B.R.), the Department of Obstetrics and Gynecology, University Munich rechts der Isar (B.S.), and the Department of Obstetrics and Gynecology, University Hospital, Ludwig-Maximilians-Universität München (A. Burges), Munich, West German Cancer Center, Department of Gynecology and Obstetrics, University of Duisburg-Essen, Duisburg (R.K.), the Department of Gynecology and Obstetrics, University Hospital Kiel, Kiel (F.H.), University Medical Center Freiburg, Freiburg (A.H.), University Medical Center Mainz, Department of Gynecology and Obstetrics, Mainz (A.H.), and the Department of Gynecology and Obstetrics, Hannover Medical School, Hannover (P. Hillemanns) - all in Germany; the Gynecologic Oncology Unit, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Istituto Nazionale Tumori (D.L., F.R.), and the Department of Gynecologic Oncology, European Institute of Oncology, University of Milan (G.A.), Milan, the Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome (G.S.), Gynecologic Oncology, Istituto Nazionale per lo Studio e la Cura dei Tumori di Napoli, IRCCS Fondazione G. Pascale, Naples (S.G.), and the Cancer Reference Center, Centro di Riferimento Oncologico, Aviano (G.G.) - all in Italy; the Department of Gynecological Oncology, University Hospitals Leuven, Leuven Cancer Institute, Leuven, Belgium (I.V.); the Department of Obstetrics and Gynecology, Medical University Innsbruck, Innsbruck, Austria (C.M.); the Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, South Korea (J.-W.K.); and the Gynecologic Oncology Center, Department of Obstetrics and Gynecology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic (D.C.).

Background: Systematic pelvic and paraaortic lymphadenectomy has been widely used in the surgical treatment of patients with advanced ovarian cancer, although supporting evidence from randomized clinical trials has been limited.

Methods: We intraoperatively randomly assigned patients with newly diagnosed advanced ovarian cancer (International Federation of Gynecology and Obstetrics stage IIB through IV) who had undergone macroscopically complete resection and had normal lymph nodes both before and during surgery to either undergo or not undergo lymphadenectomy. All centers had to qualify with regard to surgical skills before participation in the trial. Read More

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http://dx.doi.org/10.1056/NEJMoa1808424DOI Listing
February 2019
5 Reads

Opposing or complementary perspectives? Perinatal outcomes, causality, and time zero.

Paediatr Perinat Epidemiol 2019 03 27;33(2):113-115. Epub 2019 Feb 27.

School of Public Health, Oregon Health & Science University, Portland State University, Portland, Oregon.

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http://dx.doi.org/10.1111/ppe.12542DOI Listing

Correlation between Ovarian Reserve and Incidence of Ectopic Pregnancy after Fertilization and Embryo Transfer.

Yonsei Med J 2019 Mar;60(3):285-290

Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.

Purpose: To elucidate the correlation between ovarian reserve and the incidence of ectopic pregnancy (EP) following in vitro fertilization and embryo transfer (IVF/ET) cycles.

Materials And Methods: In this observational study, 430 fresh IVF/ET cycles were examined from patient data of two university hospital infertility clinics. All included patients were positive for β-human chorionic gonadotropin (hCG) at 2 weeks after oocyte retrieval via controlled ovarian stimulation. Read More

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http://dx.doi.org/10.3349/ymj.2019.60.3.285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391525PMC
March 2019
2 Reads
1.263 Impact Factor

Induction of labour at 41 weeks versus expectant management until 42 weeks (INDEX): multicentre, randomised non-inferiority trial.

BMJ 2019 02 20;364:l344. Epub 2019 Feb 20.

Department of Obstetrics and Gynaecology, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, Netherlands

Objective: To compare induction of labour at 41 weeks with expectant management until 42 weeks in low risk women.

Design: Open label, randomised controlled non-inferiority trial.

Setting: 123 primary care midwifery practices and 45 hospitals (secondary care) in the Netherlands, 2012-16. Read More

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http://www.bmj.com/lookup/doi/10.1136/bmj.l344
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http://dx.doi.org/10.1136/bmj.l344DOI Listing
February 2019
11 Reads

Effects of CytoReductive surgery plus hyperthermic IntraPEritoneal chemotherapy (HIPEC) versus CytoReductive surgery for ovarian cancer patients: A systematic review and meta-analysis.

Eur J Surg Oncol 2019 03 24;45(3):301-309. Epub 2018 Oct 24.

Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang 110004, People's Republic of China. Electronic address:

Background: The effects of Hyperthermic IntraPEritoneal Chemotherapy (HIPEC) and CytoReductive Surgery (CRS) for ovarian cancer patients remain controversial.

Methods: A systematic review and meta-analysis was conducted using PubMed, Embase and Web of Science databases to investigate Overall Survival (OS), Disease Free Survival (DFS) and adverse effects between HIPEC and CRS group.

Results: In our overall analysis (13 studies), patients in the HIPEC group exhibited a significantly improved OS (HR = 0. Read More

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http://dx.doi.org/10.1016/j.ejso.2018.10.528DOI Listing
March 2019
2 Reads

Risk of miscarriage in women with endometriosis undergoing IVF fresh cycles: a retrospective cohort study.

Reprod Biol Endocrinol 2019 Feb 12;17(1):21. Epub 2019 Feb 12.

Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Haidian district, North garden road, No 49, Beijing, People's Republic of China.

Background: Endometriosis is thought to affect the effectiveness of ART by an increased risk of miscarriage. We aimed to investigate the impact of endometriosis in women achieving singleton pregnancies through IVF fresh cycles and risk of miscarriage.

Methods: This retrospective cohort study included all women undergoing a first IVF cycle and achieving singleton pregnancies after fresh embryo transfer in a tertiary university hospital reproductive medical center between January 2008 and June 2016. Read More

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http://dx.doi.org/10.1186/s12958-019-0463-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371538PMC
February 2019
1 Read

The role of recombinant LH in women with hypo-response to controlled ovarian stimulation: a systematic review and meta-analysis.

Reprod Biol Endocrinol 2019 Feb 6;17(1):18. Epub 2019 Feb 6.

Department of Neuroscience, Reproductive Science and Odontostomatology, University of Naples Federico II, Naples, Italy.

Objective: To study the role of recombinant human LH supplementation in women with hypo-response to ovarian stimulation.

Methods: We performed a systematic review and meta-analysis of prospective clinical trials in which recombinant FSH monotherapy protocols were compared with LH-supplemented protocols in hypo-responders. A search was conducted of the Scopus, MEDLINE databases without time or language restrictions. Read More

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http://dx.doi.org/10.1186/s12958-019-0460-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366097PMC
February 2019
1 Read

Incidence, patterns and prognosis of first distant recurrence after surgically treated early stage endometrial cancer: Results from the multicentre FRANCOGYN study group.

Eur J Surg Oncol 2019 04 19;45(4):672-678. Epub 2019 Jan 19.

Department of Gynecology and Obstetrics, Tenon University Hospital, Assistance Publique des Hôpitaux de Paris (AP-HP), Sorbonne University, Paris, France; INSERM UMR S 938, Université Pierre et Marie Curie, Paris, France.

Patterns of distant metastatic failure of endometrial cancer (EC) by specific anatomic site are not well described in the literature. In this manuscript, we evaluated the metastatic patterns of EC cancer and analysed the potential distribution of metastatic disease in this malignancy.

Methods: A total of 1444 women with EC were identified. Read More

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http://dx.doi.org/10.1016/j.ejso.2019.01.011DOI Listing
April 2019
5 Reads

A Study of Pap Smears in HIV-Positive and HIV-Negative Women from a Tertiary Care Center in South India.

Acta Cytol 2019 5;63(1):50-55. Epub 2019 Feb 5.

Department of Pathology, Kasturba Medical College, Manipal Academy of Higher Education, Mangalore, India.

Objectives: The aim of this work was to study the spectrum of epithelial abnormalities on Pap smears of HIV-positive women categorized as per the Bethesda System of Reporting Cervical Cytology, to correlate them with CD4 lymphocyte counts, and to compare them with the spectrum of abnormalities seen in a HIV-negative control group. Study Design and Methodology: The present study was a 6-year retrospective study conducted in the Department of Pathology at Kasturba Medical College, Mangalore, which included 150 Pap smears from HIV-positive and HIV-negative women, respectively. The Pap-stained slides of the cases were retrieved and studied. Read More

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http://dx.doi.org/10.1159/000496211DOI Listing
March 2019
14 Reads

Association between premature ovarian insufficiency, early menopause, socioeconomic status in a nationally representative sample from Korea.

Maturitas 2019 Mar 5;121:22-27. Epub 2018 Dec 5.

Department of Occupational and Environmental Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea. Electronic address:

Objective: We investigated whether, in the Korean population, the risk of premature ovarian insufficiency (POI) and early menopause varies with a woman's socioeconomic status, evaluated in relation to income, education, and occupation.

Methods: This cross-sectional, population-based study involved 31,508 women aged >19 years registered in the Korea National Health and Nutrition Examination Survey (KNHANES) (2007-2016). Menopausal status and socioeconomic status were obtained from self-reported KNHANES data. Read More

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http://dx.doi.org/10.1016/j.maturitas.2018.12.004DOI Listing
March 2019
4 Reads

The effect of mastitis management input and implementation of mastitis management on udder health, milk quality, and antimicrobial consumption in dairy herds.

J Dairy Sci 2019 Mar 26;102(3):2401-2415. Epub 2019 Jan 26.

M-team and Mastitis and Milk Quality Research Unit, Department of Reproduction, Obstetrics and Herd Health, Faculty of Veterinary Medicine, Ghent University, 9820 Merelbeke, Belgium. Electronic address:

The main objective of this study was to evaluate evolutions in herd-level antimicrobial consumption (AMC) and in udder health and milk quality parameters between herds that received mastitis management input on a regular basis (actively advised by the first author; referred to as intervention herds) and herds that did not (referred to as control herds). Strikingly, herds in the intervention group had a significantly higher prevalence of new intramammary infections compared with those in the control group. No significant differences were observed in the percentage of chronically infected cows, the bulk milk somatic cell count, and the bacterial and coliform count between the intervention and control herds, nor did the herd-level AMC differ between them. Read More

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http://dx.doi.org/10.3168/jds.2018-15237DOI Listing

Patterns of recurrence and prognosis in locally advanced FIGO stage IB2 to IIB cervical cancer: Retrospective multicentre study from the FRANCOGYN group.

Eur J Surg Oncol 2019 04 30;45(4):659-665. Epub 2018 Dec 30.

Department of Gynaecology and Obstetrics, Tenon University Hospital, Assistance Publique des Hôpitaux de Paris (AP-HP), University Pierre and Marie Curie, Paris 6, Institut Universitaire de Cancérologie (IUC), 4 rue de la Chine, 75020, Paris, France; INSERM UMR_S_938, University Pierre et Marie Curie, Paris 6, 27 rue de Chaligny, 75012, Paris, France.

Introduction: Evidence-based data describing patterns of recurrence and prognosis in women with FIGO stage IB2 to IIB locally advanced cervical cancer (LACC) are scarce. The purpose of this study was to analyse patterns of recurrence in LACC and their correlation with prognosis, depending on FIGO stage, lymph node (LN) status and treatment modalities. The endpoints of this study were the type of recurrence (locoregional or distant, and time to recurrence), the recurrence free survival, the overall survival and the cumulative incidence for both locoregional and distant recurrence. Read More

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http://dx.doi.org/10.1016/j.ejso.2018.11.014DOI Listing
April 2019
7 Reads

Low dose human chorionic gonadotropin administration at the time of gonadotropin releasing-hormone agonist trigger versus 35 h later in women at high risk of developing ovarian hyperstimulation syndrome - a prospective randomized double-blind clinical trial.

J Ovarian Res 2019 Jan 26;12(1). Epub 2019 Jan 26.

Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Center for Advanced Reproductive Services, University of Connecticut School of Medicine, Farmington, CT, 06030, USA.

Background: Ovarian hyperstimulation syndrome remains a serious complication during in vitro fertilization cycles if high dose human chorionic gonadotropin (hCG) is used to trigger ovulation in high responder patients. Though much of this risk is mitigated with trigger using gonadotropin releasing-hormone (GnRH) agonist alone, it may result in lower birth rates. GnRH-agonist trigger and adjuvant low dose hCG has been proposed to improve birth rates, but timing of this hCG support to corpus luteum function has never been fully described. Read More

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http://dx.doi.org/10.1186/s13048-019-0483-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347742PMC
January 2019
1 Read

Chemotherapy, Biologic, and Immunotherapy Breakthroughs in Cancer Care.

Obstet Gynecol Clin North Am 2019 Mar;46(1):137-154

Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, 9618 Alta Vista Terrace, Bethesda, MD 20814, USA. Electronic address:

As the understanding of cancer biology expands, a wider array of treatment options has become available in the field of gynecologic cancer. Therapies that target specific molecular pathways are now being used. Drugs that target cancer angiogenesis, signal transduction, DNA repair, and immune evasion mechanisms are currently being used, in addition to or in lieu of traditional chemotherapy, to achieve more personalized treatment of each patient and their unique disease. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08898545183009
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http://dx.doi.org/10.1016/j.ogc.2018.09.009DOI Listing
March 2019
12 Reads

Capecitabine plus bevacizumab versus capecitabine in maintenance treatment for untreated characterised KRAS exon 2 wild-type metastatic colorectal cancer: a retrospective analysis in Chinese postmenopausal women.

BMC Gastroenterol 2019 Jan 25;19(1):17. Epub 2019 Jan 25.

Emergency Department, The First Affiliated Hospital, Sun Yat-sen University, Huangpu East Road No. 183, Huangpu District, Guangzhou, 510700, China.

Background: Capecitabine plus bevacizumab (CAP-B) maintenance treatment after 6 cycles of capecitabine, oxaliplatin, and bevacizumab (CAPOXB) has demonstrated clinical activity and failure to compromise quality of life in patients with metastatic colorectal cancer (MCC) in a previous phase 3 CAIRO3 study. The objective of this study is to evaluate the efficacy and safety of CAP-B versus CAP in maintenance treatment after 6-cycle CAPOXB induction therapy in Chinese postmenopausal women with untreated characterised KRAS exon 2 wild-type MCC.

Methods: During 2012-2016, prospectively maintained databases were reviewed to evaluate cohorts with untreated characterised KRAS exon 2 wild-type MCC and stable disease or better after 6-cycle CAPOXB induction treatment. Read More

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http://dx.doi.org/10.1186/s12876-018-0916-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346504PMC
January 2019
14 Reads
2.365 Impact Factor

The association between endometrial thickness and pregnancy outcome in gonadotropin-stimulated intrauterine insemination cycles.

Reprod Biol Endocrinol 2019 Jan 23;17(1):14. Epub 2019 Jan 23.

Department of Obstetrics and Gynaecology, University of Toronto, 123 Edward St. Suite 1200, Toronto, ON, M5G 1E2, Canada.

Background: Intrauterine insemination (IUI) is the first-line treatment for non-tubal infertility. Injectable gonadotropins are often chosen as adjunctive stimulation to promote the growth of ovarian follicles in IUI cycles. The growing follicles produce estrogen, which induces endometrial proliferation and increased endometrial stripe thickness (EST). Read More

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http://dx.doi.org/10.1186/s12958-019-0455-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345006PMC
January 2019
2 Reads
2.409 Impact Factor

Abnormal hysteroscopy findings among a cross section of infertile Nigerian women.

Niger J Clin Pract 2019 Jan;22(1):9-15

Department of Obstetrics and Gynaecology, University of Portharcout Teaching Hospital, Port Harcourt, Nigeria.

Background: Intrauterine lesions are important causes of infertility. This study aims to evaluate the abnormal findings at hysteroscopy among infertile women seen in 2 new Fertility/Gynaecological Endoscopy units in Nigeria.

Methods: A prospective study of 159 infertile women who had diagnostic hysteroscopy in Nnamdi Azikiwe University Teaching hospital Nnewi and Holy Rosary Specialist Hospital, Onitsha to evaluate the intrauterine lesions seen. Read More

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http://dx.doi.org/10.4103/njcp.njcp_404_17DOI Listing
January 2019
8 Reads

Effect of Anterior Compartment Endometriosis Excision on Infertility.

JSLS 2018 Oct-Dec;22(4)

Department of Gynecology, University of Strasbourg, Strasbourg, France and Latifa Hospital, Dubai, United Arab Emirates.

Background And Objectives: Laparoscopic surgical excision of bladder nodules has been demonstrated to be effective in relieving associated painful symptoms; the data are lacking concerning the impact of anterior compartment endometriosis on infertility. We conducted this study to evaluate whether or not the surgical excision of deep endometriosis affecting the anterior compartment plays a role in restoring fertility.

Methods: This multicentre, retrospective study included a group of 55 patients presenting with otherwise-unexplained infertility who had undergone laparoscopic excision of anterior compartment endometriosis with histological confirmation. Read More

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http://dx.doi.org/10.4293/JSLS.2018.00067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328363PMC
March 2019
4 Reads

Maternal near-miss morbidity: is this evidence of maternal health quality in sub-Saharan Africa?

Authors:
F Okonofua

BJOG 2019 05 20;126(6):762. Epub 2019 Feb 20.

Obstetrics and Gynaecology, College of Medical Sciences, Women's Health and Action Research Centre, University of Benin, Benin City, Edo State, Nigeria.

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http://dx.doi.org/10.1111/1471-0528.15619DOI Listing

Donation After Cardiac Death in Liver Transplantation: An Additional Source of Organs With Similar Results to Donation After Brain Death.

Transplant Proc 2019 Jan - Feb;51(1):4-8. Epub 2018 Jun 28.

Department of Surgery, Obstetrics and Ginecology, Faculty of Medicine, Universidad de Málaga, Málaga, Spain; Hepatobiliopancreatic Surgery and Transplant Unit, General and Digestive Surgery Service, Hospital Regional Universitario de Málaga, Málaga, Spain.

Background: As new sources of organs are needed, liver transplantation using donors after cardiac death (DCD) is progressively increasing, but outcomes with this method are still questioned. This study was accomplished to verify that DCD outcomes are comparable to those seen in donation after brain death (DBD).

Methods: This was a prospective cohort study including 100 liver transplantation performed between 2014 and 2017, divided according to donor type in 75 DBD and 25 DCD. Read More

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http://dx.doi.org/10.1016/j.transproceed.2018.02.208DOI Listing
March 2019
4 Reads

Risk Factors for Mortality in Children with Congenital Heart Disease Delivered at a Brazilian Tertiary Center.

Braz J Cardiovasc Surg 2018 Nov-Dec;33(6):603-607

Discipline of Fetal Medicine, Department of Obstetrics, Escola Paulista de Medicina da Universidade Federal de São Paulo (EPM-UNIFESP), São Paulo, SP, Brazil.

Objective: This study aims to investigate the incidence of postnatal diagnosis of congenital heart disease (CHD) and the predictive factors for hospital mortality.

Methods: This retrospective cohort study was conducted at a Brazilian tertiary center, and data were collected from medical records with inclusion criteria defined as any newborn with CHD diagnosed in the postnatal period delivered between 2015 and 2017. Univariate and multivariate analyses were performed to determine the potential risk factors for mortality. Read More

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http://dx.doi.org/10.21470/1678-9741-2018-0174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326451PMC
March 2019
1 Read

Large cell neuroendocrine carcinoma of the uterine cervix.

BMJ Case Rep 2019 Jan 14;12(1). Epub 2019 Jan 14.

Department of Obstetrics and Gynaecology, Medway Maritime Hospital, Gillingham, UK.

We report a case of large cell neuroendocrine carcinoma of the uterine cervix. A 33-year-old woman presented with a 4-month history of irregular vaginal bleeding and suspicious cervix. Transvaginal ultrasound showed a 3×3. Read More

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http://dx.doi.org/10.1136/bcr-2018-225880DOI Listing
January 2019
3 Reads

Cervical cancer.

Lancet 2019 01;393(10167):169-182

Department Obstetrics and Gynaecology, University of Cape Town, Cape Town, South Africa; South African Medical Research Council, Gynaecological Cancer Research Centre, Tygerberg, South Africa.

Each year, more than half a million women are diagnosed with cervical cancer and the disease results in over 300 000 deaths worldwide. High-risk subtypes of the human papilloma virus (HPV) are the cause of the disease in most cases. The disease is largely preventable. Read More

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http://dx.doi.org/10.1016/S0140-6736(18)32470-XDOI Listing
January 2019
2 Reads

A rare case of partial trisomy 8q24.12-q24.3 and partial monosomy of 8q24.3: Prenatal diagnosis and clinical findings.

Taiwan J Obstet Gynecol 2019 Jan;58(1):36-39

Regional Center of Medical Genetics Timis, Clinical Emergency Hospital for Children "Louis Turcanu" Timisoara, Timisoara, Romania. Electronic address:

Objective: We describe a rare case of "pure" 8q duplication diagnosed prenatally by conventional karyotyping, that was further characterized by array comparative genomic hybridization (aCGH).

Case Report: A 39-year-old, primigravida woman underwent amniocentesis at 23 weeks of gestation because of an abnormal second trimester maternal serum screening for Down syndrome. Conventional cytogenetic analysis demonstrated a karyotype of 46,XX,der(8) (q24. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10284559183027
Publisher Site
http://dx.doi.org/10.1016/j.tjog.2018.11.005DOI Listing
January 2019
6 Reads